Method for preparing micro-nano fiber film by electrostatic spinning method

A micro-nano fiber, electrospinning technology, applied in spinning solution preparation, fiber processing, textiles and papermaking, etc., can solve the problem that it is difficult to use conventional surgical dressing and treatment methods, wound peripheral protection does not play a good role, and Unable to effectively control wound infection and other problems, to achieve the effect of convenient dressing change, convenient observation of wound condition, and good biocompatibility

CN102965838AInactive Publication Date: 2013-03-13QINGDAO UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2013-03-13
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

The invention belongs to the technical field of electrostatic spinning and relates to a method for preparing a micro-nano fiber film by an electrostatic spinning method. The method comprises the steps as follows: firstly, mixing polyvinylpyrrolidone powder with absolute ethanol, adding epidermal growth factor, magnetically stirring at room temperature for fully dispersing, and standing to obtain a precursor electrostatic spinning solution for electrostatic spinning; secondly, extracting the prepared electrostatic spinning solution by using a disinfected injection needle tube, and placing a mounted electrostatic spinning device at the periphery of a wound; thirdly, turning on a switch of the electrostatic spinning device for electrostatic spinning, forming a layer of uniform micro-nano fiber film at the wound, taking down the original micro-nano fiber film prepared by electrostatic spinning in 24 hours, and repeating the steps and carrying out electrostatic spinning once by facing to the wound; and deducing the rest by analogy for auxiliary treatment of the wound. According to the method, the process steps are simple, the preparation operation is flexible, the preparation cost is low, the film is good in air permeability, favorable for treating and healing the wound, and environment-friendly.
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Description

Technical field:

[0001] The invention belongs to the technical field of electrospinning, and relates to the application of a novel portable hand-held electrospinning device, a new process for preparing a fiber film capable of covering injured skin wounds by using electrospinning technology, in particular to an electrospinning process A method for preparing micro-nano fiber film by silk method. Background technique:

[0002] At present, burns or skin injuries are common accidental traumas that seriously endanger human health. People are threatened by fires and traffic accidents from nature and humans all the time. Especially with the development of science, People's daily life and production are surrounded by combustible materials. The fire hazard is very serious. Burn patients are often scarred and unrecognizable. In severe cases, they will cause permanent disabilities or even life-threatening; Necrosis, vascular embolism, and poor local blood supply cannot effectively cont...

Examples

Embodiment

[0012] This embodiment includes three process steps of spinning solution preparation, spinning device installation and electrospinning micro-nano fiber film:

[0013] Spinning solution preparation: The prepared spinning solution is an ethanol solution of polyvinylpyrrolidone (PVP, molecular weight 1.3 million) mixed with epidermal growth factor (epidermal growth factor, EGF) with a mass fraction of 13 wt%. Mix 1.3 grams of polyvinylpyrrolidone (PVP) powder with 8.7 grams of absolute ethanol, then add 0.02 grams of epidermal growth factor (EGF), and stir magnetically at room temperature for 2 hours to fully disperse the EGF and then let it stand for 0.5 hours to obtain a uniform A precursor electrospinning solution for transparent electrospinning;

[0014] Spinning device installation: extract the prepared electrospinning solution with a sterilized injection needle in a sterile room, then install the needle on the syringe as a spinning nozzle, and then install the syringe on a ...