A fully automatic slide-slide staining machine capable of continuous sampling and used for blood smear preparation
By designing a fully automatic sheet-pushing dyeing machine containing multiple automation devices, the problem of single function of existing blood smear preparation instruments is solved, and a fully automatic blood smear preparation process is realized, which improves efficiency and quality.
Patent Information
- Application Number
- CN202010128140.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-02-28
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2040-02-28
AI Technical Summary
The existing blood smear preparation instrument has relatively single functions and cannot be fully automatic pushing and dyeing, resulting in low efficiency in blood smear preparation.
A fully automatic push-and-tear dyeing machine that can be continuously injected and used for blood smear preparation is designed, including body frame, sample slide, slide loading and flipping device, sampling and liquid support device, pushing and drying device, Dyeing and liquid support device, sample output connection bridge device, control circuit, information processing device and display device to realize fully automatic sampling, dropping, pushing, dyeing and liquid cleaning.
Through a fully automated process, the efficiency of blood smear preparation is significantly improved, the time and error of manual operation is reduced, and the consistency and safety of blood membrane quality is ensured.
Smart Images

Figure CN111238909B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of medical devices, and in particular to a full-automatic slide-pushing and staining machine capable of continuous sampling and used for blood smear preparation. Background Art
[0002] At present, for a long time, the microscopic examination of peripheral blood cell morphology has been the last link in clinical examinations and is known as the "gold standard of clinical examinations". The preparation of blood smears is an indispensable part of the microscopic examination of blood cell morphology. At present, most of the blood smears produced in domestic hospitals every day are made manually. Since the preparation of blood smears mainly includes sampling, dripping, pushing, staining, drying and other steps, this relatively numerous process, if made manually, will lead to extremely low efficiency in blood smear preparation, long labor time, and the quality of blood film is more affected by the subjective influence of medical staff, lacking a unified standard. On the other hand, manual preparation of blood smears requires direct contact with blood samples, which poses certain biological hazards. Therefore, blood smear preparation equipment has appeared on the market and has been used in some hospitals. However, the functions of these blood smear preparation instruments are relatively single, and they can only push or stain, and cannot push and stain fully automatically, making the blood smear preparation efficiency low. Summary of the invention
[0003] The object of the present invention is to provide a fully automatic slide pushing and staining machine that can continuously feed samples and is used for blood smear preparation, aiming to solve the technical problem that the blood smear preparation instruments in the prior art have relatively single functions, can only push the slide or can only stain, cannot push the slide and stain fully automatically, and have low blood smear preparation efficiency.
[0004] To achieve the above-mentioned purpose, the present invention adopts a fully automatic slide-pushing and staining machine that can continuously inject samples and is used for preparing blood smears, including a body frame, a sample glass slide, a glass slide loading and turning device, a sampling and liquid circuit support device, a slide-pushing and drying device, a staining and liquid circuit support device, a sample output connection bridge device, a control circuit and an information processing device, and a display device; the sample glass slide is slidably connected to the glass slide loading and turning device and is located on the surface of the glass slide loading and turning device, the glass slide loading and turning device is fixedly connected to the body frame and is connected to the sample glass slide through a bracket, and the sampling and liquid circuit support device The device is fixedly connected to the body frame, cooperates with the slide loading and flipping device, and is close to the sample slide. The slide pushing and drying device is fixedly connected to the body frame, and cooperates with the sampling and liquid circuit supporting device. The staining and liquid circuit supporting device is fixedly connected to the body frame, and cooperates with the slide pushing and drying device, and faces the direction of the sample slide. The sample output connection bridge device is fixedly connected to the body frame, and cooperates with the staining and liquid circuit supporting device. The sample slide is placed in a slide box and is slidably connected to the sample output connection bridge device through the slide box. The control circuit The control circuit and information processing device are fixedly connected to the body frame, receive detection signals, and send operation signals; the display device is fixedly connected to the body frame, and operates the control circuit and information processing device; the slide loading and flipping device includes a slide loading slide, a slide lever, a slide flipping platform and a driving component, the slide loading slide is fixedly connected to the body frame, and the sample slide is driven to slide by the driving component, the slide lever is rotatably connected to the slide loading slide through the bracket, abuts against the sample slide, and drives the sample slide to slide, the slide flipping platform The table cooperates with the slide loading slide, and transports the sample slide through the driving component, and flips over under the drive of the driving component; the sampling and liquid circuit support device includes a sampling motor, a sample dripping motor and a liquid circuit cleaner, the sampling motor is fixedly connected to the body frame, and controls the sampling needle to approach the serum sample, the sample dripping motor is fixedly connected to the body frame, and controls the up and down movement of the sample dripping needle, and toward the direction of the sample slide, the liquid circuit cleaner is fixedly connected to the body frame, cooperates with the sampling motor and the sample dripping motor to complete the sampling and sample dripping actions, and cleans the sampling and sample dripping pipelines.
[0005] Wherein, the driving assembly includes a first motor, a second motor, a third motor and a fourth motor, the first motor is fixedly connected to the body frame through a bracket, and is retracted toward the direction of the glass slide loading slide; the second motor is connected to the glass slide lever through a conveyor belt, and drives the glass slide lever to push out the sample glass slide; the third motor is connected to the glass slide flipping platform through a coupling, and drives the glass slide flipping platform to flip through an output shaft; the fourth motor is fixedly connected to the body frame through a bracket, and drives the third motor and the glass slide flipping platform to move toward the direction of the slide pushing and drying device.
[0006] Among them, the slide pushing and drying device includes a transverse translation unit, a longitudinal translation unit, and a push knife rotating unit. The transverse translation unit is slidably connected to the body frame through a bracket, and drives the longitudinal translation unit to slide transversely through a guide rail; the longitudinal translation unit is slidably connected to the body frame through a bracket, and drives the push knife rotating unit to slide longitudinally through a guide rail; the push knife rotating unit abuts against the sample glass slide and slides on the surface of the sample glass slide.
[0007] Among them, the transverse translation unit includes a transverse screw motor and a transverse guide rail slider. The transverse screw motor is fixedly connected to the body frame through a bracket, and is connected to the transverse guide rail slider, and drives the transverse guide rail slider to slide; the transverse guide rail slider is rotationally connected to the transverse screw motor and is connected to the longitudinal translation unit to complete the left and right movement of the longitudinal translation unit, thereby realizing the left and right movement of the push knife rotation unit and completing the sheet pushing action.
[0008] Among them, the longitudinal translation unit includes a longitudinal screw motor and a longitudinal guide rail slider. The longitudinal screw motor is fixedly connected to the body frame through a bracket, and is connected to the longitudinal guide rail slider, and drives the longitudinal guide rail slider to slide; the longitudinal guide rail slider is connected to the longitudinal screw motor and to the push-blade rotation unit to complete the up and down movement of the push-blade rotation unit.
[0009] Among them, the staining and liquid path support device includes a glass slide clamping assembly and a staining tank. The glass slide clamping assembly is slidably connected to the body frame through a bracket, and is fixedly connected to the sample glass slide, and drives the sample glass slide into the staining tank; the staining tank is fixedly connected to the body frame, and is connected to the liquid path cleaner through a conduit.
[0010] Among them, the glass slide clamping assembly includes a clamping drive component, a mechanical claw motor and a mechanical claw. The clamping drive component is slidably connected to the body frame through a bracket, and drives the mechanical claw motor and the mechanical claw to move; the mechanical claw motor is slidably connected to the body frame through the clamping drive component, and drives the mechanical claw to move; the mechanical claw is fixedly connected to the mechanical claw motor, and clamps the sample glass slide.
[0011] Among them, the clamping driving component includes a transverse translation motor and a longitudinal translation motor. The transverse translation motor is slidably connected to the body frame through a bracket, and drives the longitudinal translation motor to slide through a synchronous belt; the longitudinal translation motor is slidably connected to the transverse translation motor through a guide rail, and is connected to the mechanical claw motor through a synchronous belt, and drives the mechanical claw motor to slide.
[0012] Wherein, the sample output connection bridge device includes a sample input and output tray, a fifth motor, a bottom dial component, a sixth motor, a horizontal sample input lever and a sample output assembly, wherein the sample input and output tray is fixedly connected to the body frame and is slidably connected to the sample glass slide; the fifth motor is fixedly connected to the body frame through a bracket, and drives the bottom dial component to move through a synchronous belt, and drives the slide box containing the sample glass slide to slide; the bottom dial component is connected to the fifth motor, and is fixedly connected to the slide box containing the sample glass slide, and drives the slide box to move; the sixth motor is fixedly connected to the body frame through a bracket, and drives the horizontal sample input lever to move through a synchronous belt; the horizontal sample input lever is rotationally connected to the sixth motor, and is fixedly connected to the sample glass slide, and drives the sample glass slide to move horizontally; the sample output assembly cooperates with the sample input and output tray, and drives the sample glass slide to move.
[0013] Wherein, the sample output assembly includes a seventh motor, a horizontal sample output lever and an eighth motor, the seventh motor is fixedly connected to the body frame through a bracket, and is rotatably connected to the bottom output component through a synchronous belt, and drives the bottom output component and the sample slide to move; the horizontal sample output lever is rotatably connected to the body frame through a bracket, and is connected to the sample slide through the eighth motor; the eighth motor is fixedly connected to the body frame through a bracket, and is connected to the horizontal sample output lever through a synchronous belt, and drives the horizontal sample output lever and the sample slide to move.
[0014] The present invention provides a fully automatic slide pushing and staining machine that can continuously feed samples and is used for blood smear preparation. After the detector detects the sample slide information, the control circuit board controls the second motor to rotate forward, and drives the slide lever to move through the belt, guide rail and slider method. The slide lever pushes out the bottom slide in the loaded slide box, thereby realizing the loading of the sample slide. After the radio frequency circuit board detects the slide information on the sample slide, the signal is transmitted to the control circuit and the information processing device, and a signal is promptly sent to the second motor to push the sample slide to the blood dripping position, and a signal is simultaneously sent to the liquid circuit cleaner to complete the sample sampling and sample dripping actions. After the sample is dripped onto the sample slide, the sampling needle and the sample dripping needle and their pipelines are cleaned in time, which can realize fully automatic sampling, sample dripping, slide pushing, staining and liquid circuit cleaning actions, making the blood smear preparation more efficient. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0016] Figure 1 This is the general assembly diagram of the fully automatic slide-pushing and staining machine of the present invention which can continuously inject samples and is used for preparing blood smears.
[0017] Figure 2 The present invention is a three-dimensional structural schematic diagram of a fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation.
[0018] Figure 3 The present invention is a schematic diagram of the internal structure of a fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation.
[0019] Figure 4 The present invention is a schematic plan view of a fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for preparing blood smears.
[0020] Figure 5 It is a schematic diagram of the three-dimensional structure of the slide loading and flipping device of the present invention.
[0021] Figure 6 It is a schematic diagram of the three-dimensional structure of the sampling and liquid path support device of the present invention.
[0022] Figure 7 It is a three-dimensional structural schematic diagram of the sheet pushing and drying device of the present invention.
[0023] Figure 8 It is a schematic diagram of the partial three-dimensional structure of the dyeing and liquid path supporting device of the present invention.
[0024] Fig. 9 The invention discloses a schematic diagram of a sample feeding structure of a fully automatic slide-pushing dyeing machine.
[0025] Fig.10 It is a three-dimensional structural schematic diagram of the sample connecting bridge device of the present invention.
[0026] In the figure: 1-slide loading and turning device, 2-sampling and liquid circuit support device, 3-slide pushing and drying device, 4-staining and liquid circuit support device, 5-sample connection bridge device, 6-control circuit and information processing device, 7-display device, 8-body frame, 9-driving assembly, 10-slide loading slide, 11-lateral translation unit, 12-longitudinal translation unit, 13-clamping driving member, 14-sample discharging assembly, 30-push knife rotation unit, 41-slide clamping assembly, 42-staining and liquid circuit support unit, 100-full-automatic slide pushing and staining machine capable of continuous sampling and used for blood smear preparation, 101-L-type loading module mounting base plate, 102- A motor, 103-slide loading module left slide, 104-slide loading module left support plate, 105-first detector, 106-slide lever, 107-slide loading module right support plate, 108-sample slide, 109-loading slide box, 110-RF circuit board, 111-slide loading module right slide, 112-second motor, 113-camera, 114-slide flip platform, 115-flexible coupling, 116-third motor, 117-fourth motor, 201-sampling component, 202-drip sample component, 301-fixed foot block, 302-slide push main support plate, 303-transverse guide slider, 304-transverse screw rod Motor, 305-push piece reinforcement fixing plate, 306-longitudinal motor support plate, 307-longitudinal screw motor, 308-longitudinal guide rail slider, 309-direct push motor, 310-push knife, 311-push knife cleaning tank, 312-push knife drying and wiping device, 401-clamping module base, 402-lateral translation motor, 403-lateral translation guide rail, 404-longitudinal translation support, 405-longitudinal translation motor, 406-longitudinal translation guide rail, 407-mechanical claw motor, 408-mechanical claw, 409-staining tank, 501-L-type connecting bottom plate, 502-bottom dial component, 503-in and out sample tray, 504-U-type motor support plate, 5 05-fifth motor, 506-infrared counter-radiation sensor, 507-sixth motor, 508-lateral sample injection support plate, 509-first sensor, 510-lateral sample injection lever, 511-second sensor, 512-seventh motor, 513-sample output control assembly, 514-third sensor, 515-eighth motor, 516-lateral sample output support plate, 517-lateral sample output lever, 518-slide box, 519-channel separator, 801-bottom plate frame, 802-front panel support plate, 803-top frame, 804-syringe support plate, 805-control circuit support plate, 2011-sampling motor, 2021-drip motor. DETAILED DESCRIPTION
[0027] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.
[0028] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, in the description of the present invention, "multiple" means two or more, unless otherwise clearly and specifically defined.
[0029] In the first example of this embodiment:
[0030] See also Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , Figure 7 and Fig. 9The present invention provides a fully automatic slide-pushing and staining machine 100 capable of continuous sample introduction and used for blood smear preparation, comprising a machine frame 8, a sample glass slide 108, a glass slide loading and flipping device 1, a sampling and liquid circuit support device 2, a slide-pushing and drying device 3, a staining and liquid circuit support device 4, a sample connection bridge device 5, a control circuit and information processing device 6 and a display device 7; the sample glass slide 108 is slidably connected to the glass slide loading and flipping device 1 and is located on the surface of the glass slide loading and flipping device 1, the glass slide loading and flipping device 1 is fixedly connected to the machine frame 8 and connected to the sample glass slide 108 through a bracket, and the sampling and liquid circuit support device 2 is fixedly connected to the machine frame 8 , and cooperates with the slide loading and flipping device 1, and is close to the sample slide 108, the slide pushing and drying device 3 is fixedly connected to the body frame 8, and cooperates with the sampling and liquid circuit support device 2, the staining and liquid circuit support device 4 is fixedly connected to the body frame 8, and cooperates with the slide pushing and drying device 3, and faces the direction of the sample slide 108, the sample connection bridge device 5 is fixedly connected to the body frame 8, and cooperates with the staining and liquid circuit support device 4, the sample slide 108 is placed in a slide box, and is slidably connected to the sample connection bridge device 5 through the slide box, the control circuit and information processing device 6 are fixedly connected to the body frame 8, and receives detection signals and sends operation signals; the display device 7 is fixedly connected to the body frame 8 and controls the control circuit and the information processing device 6; the slide loading and flipping device 1 includes a slide loading slide 10, a slide lever 106, a slide flipping platform 114 and a driving component 9, the slide loading slide 10 is fixedly connected to the body frame 8, and drives the sample slide 108 to slide through the driving component 9, the slide lever 106 is rotatably connected to the slide loading slide 10 through a bracket, and abuts against the sample slide 108, and drives the sample slide 108 to slide, the slide flipping platform 114 cooperates with the slide loading slide 10, The sample slide 108 is transported by the driving component 9 and flipped under the drive of the driving component 9; the sampling and liquid circuit support device 2 includes a sampling motor 2011, a sample dripping motor 2021 and a liquid circuit cleaner 203, the sampling motor 2011 is fixedly connected to the body frame 8, and controls the sampling needle to approach the serum sample, the sample dripping motor 2021 is fixedly connected to the body frame 8, and controls the up and down movement of the sample dripping needle, and toward the direction of the sample slide 108, the liquid circuit cleaner 203 is fixedly connected to the body frame 8, cooperates with the sampling motor 2011 and the sample dripping motor 2021 to complete the sampling and sample dripping actions, and cleans the sampling and sample dripping pipelines.
[0031] Furthermore, the driving assembly 9 includes a first motor 102, a second motor 112, a third motor 116 and a fourth motor 117, the first motor 102 is fixedly connected to the body frame 8 through a bracket, and is retracted toward the direction of the glass slide loading slide 10; the second motor 112 is connected to the glass slide lever 106 through a conveyor belt, and drives the glass slide lever 106 to push out the sample glass slide 108; the third motor 116 is connected to the glass slide flipping platform 114 through a coupling, and drives the glass slide flipping platform 114 to flip through an output shaft; the fourth motor 117 is fixedly connected to the body frame 8 through a bracket, and drives the third motor 116 and the glass slide flipping platform 114 to move toward the direction of the slide pushing and drying device 3.
[0032] In this embodiment, the slide loading and flipping device 1 mainly includes an L-shaped loading mounting base plate 101 and a slide loading component and a slide flipping component installed on the L-shaped loading mounting base plate. At the same time, the slide loading and flipping device is fixed on the base plate frame 801 through the L-shaped loading mounting base plate 101, wherein the driving component includes a first motor, a second motor, a third motor and a fourth motor. A left slide loading support plate 104 and a right slide loading support plate 107 are fixed on the left and right sides of the L-shaped loading mounting base plate 101 respectively, and a left slide loading slide 103 and a right slide loading slide 111 for slide loading guide are respectively installed on the support plates. The first motor 102 is installed on the vertical surface of the L-shaped loading mounting base plate 101 near one end of the instrument screen, and the motor nut is connected to the loading slide box 109 by using an L-shaped folding plate, and a smooth movement structure of a guide rail plus a slider is adopted to realize the telescopic movement of the loading slide box 109. When the first detector 105 detects that there is no glass slide in the loading glass slide box 109 and sends this signal to the control circuit board, the control circuit board sends a signal to make the first motor 102 extend. After enough glass slides are added, the first motor 102 retracts. At this time, after the first detector 105 detects the information of the sample glass slide 108, the control circuit board controls the second motor 112 to rotate forward, and drives the glass slide lever 106 to move through the belt, guide rail and slider method. The glass slide lever 106 pushes the bottom glass slide in the loading glass slide box 109, thereby realizing the loading of the sample glass slide 108. After the loading of the previous glass slide is completed, the next sample glass slide 108 will fall naturally under the action of gravity, thereby realizing continuous loading and sampling of glass slides; a radio frequency card tag is attached to the sample glass slide 108 for storing sample related information; a radio frequency circuit board 110 is fixed to the right support plate 108 for glass slide loading through a radio frequency circuit board connecting plate, and when the sample glass slide 108 is loaded to a certain position, the sample information on the sample glass slide 108 is read through the radio frequency circuit board 110 for querying and tracking the running sample, while ensuring the reliability of consistent sample information.When the blood dripping on the sample glass slide 108 is completed, the second motor 112 continues to drive the glass slide lever 106 to move forward through the belt, guide rail and slider until the sample glass slide 108 is pushed to the glass slide flipping platform 114. At this time, the glass slide flipping platform 114 is in a horizontal position, and the sample glass slide 108 is fixed by a spring clip, so that the sample completes the blood film pushing action on the glass slide flipping platform 114; the glass slide flipping platform 114 is connected to the third motor 116 through the shaft plus flexible coupling 115, and is fixedly installed on the guide rail of the horizontal surface of the L-shaped loading installation base plate 101 through the slider respectively, and the third motor 116 is used to rotate the glass slide 108. The positive and negative rotation of the slide flipping platform 114 completes the horizontal or vertical flipping action of the slide flipping platform 114; after the sample slide 108 is pushed to the slide flipping platform 114, the fourth motor 117 installed on the vertical surface of the L-shaped loading installation base plate 101 close to the control circuit and the information processing device 6 moves the third motor 116 and the slide flipping platform 114 toward the slide pushing and drying device 3 until the sample slide 108 reaches the specified slide pushing position; the sampling and liquid circuit support device 2 includes the sampling component 201 and the sample dripping component 202, and the sampling component 201 includes the sampling motor 2011, the sample dripping component 202 The sample dropping motor 2021 is included. The sampling motor 2011 is fixed on the front support plate 802. The sampling motor 2011 controls the up and down movement of the sampling needle to realize the extension and retraction of the sampling needle. The sample dropping motor 2021 is fixed on the bottom plate frame 801. The liquid path cleaner 203 mainly consists of 2 syringes, 1 liquid displacement pump, and 8 solenoid valves as control units. The two syringes in the liquid path cleaner 203 respectively use large-displacement and micro-injections. The large-displacement syringe is combined with the micro-injection syringe to realize fast sampling and liquid path cleaning, and the micro-injection syringe realizes micro-sample dropping. The two solenoid valves V5 and V6 respectively use pinch valves to realize fast sampling and sample dropping. The invention can quickly respond and effectively control the liquid flow, and is convenient for cleaning. After the radio frequency circuit board 110 detects the slide information on the sample slide 108, the signal is transmitted to the control circuit and the information processing device 6, and a signal is promptly sent to the second motor 112 to push the sample slide 108 to the blood dripping position, and a signal is simultaneously sent to the liquid circuit cleaner to complete the sample sampling and sample dripping actions. After the sample is dripped onto the sample slide 108, the sampling needle and the sample dripping needle and their pipelines are cleaned in time, and the sample dripping needle is controlled to move up and down by the sample dripping motor 2021 to realize the extension and retraction of the sample dripping needle. In this way, the fully automatic sampling, sample dripping and liquid circuit cleaning actions can be realized, so that the blood smear preparation efficiency is higher.
[0033] In the second embodiment of this embodiment:
[0034] See also Figures 1 to 10The present invention provides a fully automatic slide-pushing and staining machine 100 capable of continuous sample introduction and used for blood smear preparation, comprising a machine frame 8, a sample glass slide 108, a glass slide loading and flipping device 1, a sampling and liquid circuit support device 2, a slide-pushing and drying device 3, a staining and liquid circuit support device 4, a sample connection bridge device 5, a control circuit and information processing device 6 and a display device 7; the sample glass slide 108 is slidably connected to the glass slide loading and flipping device 1 and is located on the surface of the glass slide loading and flipping device 1, the glass slide loading and flipping device 1 is fixedly connected to the machine frame 8 and connected to the sample glass slide 108 through a bracket, and the sampling and liquid circuit support device 2 is fixedly connected to the machine frame 8 The slide loading and flipping device 1 is connected to the machine body frame 8 and cooperates with the slide loading and flipping device 1, and is close to the sample slide 108. The slide pushing and drying device 3 is fixedly connected to the machine body frame 8 and cooperates with the sampling and liquid circuit supporting device 2. The staining and liquid circuit supporting device 4 is fixedly connected to the machine body frame 8 and cooperates with the slide pushing and drying device 3, and faces the direction of the sample slide 108. The sample output connection bridge device 5 is fixedly connected to the machine body frame 8 and cooperates with the staining and liquid circuit supporting device 4. The sample slide 108 is placed in a slide box and is slidably connected to the sample output connection bridge device 5 through the slide box. The control circuit and information processing device 6 is fixedly connected to the machine body frame 8. The display device 7 is fixedly connected to the body frame 8 and controls the control circuit and the information processing device 6; the slide loading and flipping device 1 includes a slide loading slide 10, a slide lever 106, a slide flipping platform 114 and a driving component 9. The slide loading slide 10 is fixedly connected to the body frame 8 and drives the sample slide 108 to slide through the driving component 9. The slide lever 106 is rotatably connected to the slide loading slide 10 through a bracket and abuts against the sample slide 108, driving the sample slide 108 to slide. The slide flipping platform 114 cooperates with the slide loading slide 10 , and the sample slide 108 is transported by the driving component 9, and flipped under the drive of the driving component 9; the sampling and liquid circuit support device 2 includes a sampling motor 2011, a sample dripping motor 2021 and a liquid circuit cleaner 203, the sampling motor 2011 is fixedly connected to the body frame 8, and controls the sampling needle to approach the serum sample, the sample dripping motor 2021 is fixedly connected to the body frame 8, and controls the up and down movement of the sample dripping needle, and toward the direction of the sample slide 108, the liquid circuit cleaner 203 is fixedly connected to the body frame 8, cooperates with the sampling motor 2011 and the sample dripping motor 2021 to complete the sampling and sample dripping actions, and cleans the sampling and sample dripping pipelines.
[0035] Furthermore, the driving assembly 9 includes a first motor 102, a second motor 112, a third motor 116 and a fourth motor 117, the first motor 102 is fixedly connected to the body frame 8 through a bracket, and is retracted toward the direction of the glass slide loading slide 10; the second motor 112 is connected to the glass slide lever 106 through a conveyor belt, and drives the glass slide lever 106 to push out the sample glass slide 108; the third motor 116 is connected to the glass slide flipping platform 114 through a coupling, and drives the glass slide flipping platform 114 to flip through an output shaft; the fourth motor 117 is fixedly connected to the body frame 8 through a bracket, and drives the third motor 116 and the glass slide flipping platform 114 to move toward the direction of the slide pushing and drying device 3.
[0036] Furthermore, the sheet pushing and drying device 3 includes a transverse translation unit 11, a longitudinal translation unit 12, and a push knife rotating unit 30. The transverse translation unit 11 is slidably connected to the body frame 8 through a bracket, and drives the longitudinal translation unit 12 to slide transversely through a guide rail; the longitudinal translation unit 12 is slidably connected to the body frame 8 through a bracket, and drives the push knife rotating unit 30 to slide longitudinally through a guide rail; the push knife rotating unit 30 abuts against the sample glass slide 108 and slides on the surface of the sample glass slide 108.
[0037] Furthermore, the transverse translation unit 11 includes a transverse screw motor 304 and a transverse guide rail slider 303. The transverse screw motor 304 is fixedly connected to the body frame 8 through a bracket, and is connected to the transverse guide rail slider 303, and drives the transverse guide rail slider 303 to slide; the transverse guide rail slider 303 is rotationally connected to the transverse screw motor 304, and is connected to the longitudinal translation unit 12, completing the left and right movement of the longitudinal translation unit 12, thereby realizing the left and right movement of the push knife rotation unit 30 and completing the sheet pushing action.
[0038] Furthermore, the longitudinal translation unit 12 includes a longitudinal screw motor 307 and a longitudinal guide rail slider 308. The longitudinal screw motor 307 is fixedly connected to the body frame 8 through a bracket, and is connected to the longitudinal guide rail slider 308, and drives the longitudinal guide rail slider 308 to slide; the longitudinal guide rail slider 308 is connected to the longitudinal screw motor 307 and to the push-blade rotation unit 30, completing the up and down movement of the push-blade rotation unit 30.
[0039] Furthermore, the staining and liquid path support device 4 includes a glass slide clamping assembly 41 and a staining tank 409. The glass slide clamping assembly 41 is slidably connected to the body frame 8 through a bracket, and is fixedly connected to the sample glass slide 108, and drives the sample glass slide 108 into the staining tank 409; the staining tank 409 is fixedly connected to the body frame 8, and is connected to the liquid path cleaner 203 through a conduit.
[0040] Furthermore, the glass slide clamping assembly 41 includes a clamping drive component 13, a mechanical claw motor 407 and a mechanical claw 408. The clamping drive component 13 is slidably connected to the body frame 8 through a bracket, and drives the mechanical claw motor 407 and the mechanical claw 408 to move; the mechanical claw motor 407 is slidably connected to the body frame 8 through the clamping drive component 13, and drives the mechanical claw 408 to move; the mechanical claw 408 is fixedly connected to the mechanical claw motor 407, and clamps the sample glass slide 108.
[0041] Furthermore, the clamping drive component 13 includes a transverse translation motor 402 and a longitudinal translation motor 405. The transverse translation motor 402 is slidably connected to the body frame 8 through a bracket, and drives the longitudinal translation motor 405 to slide through a synchronous belt; the longitudinal translation motor 405 is slidably connected to the transverse translation motor 402 through a guide rail, and is connected to the mechanical claw motor 407 through a synchronous belt, and drives the mechanical claw motor 407 to slide.
[0042] Furthermore, the sample discharging connection bridge device 5 includes a sample discharging tray 503, a fifth motor 505, a bottom shifting component 502, a sixth motor 507, a horizontal sample discharging lever 510 and a sample discharging assembly 14, wherein the sample discharging tray 503 is fixedly connected to the body frame 8 and is slidably connected to the sample slide 108; the fifth motor 505 is fixedly connected to the body frame 8 through a bracket, and drives the bottom shifting component 502 to move through a synchronous belt, and drives the slide box containing the sample slide 108 to slide; the bottom shifting component 502 is connected to the body frame 8, and ... The fifth motor 505 is connected and fixedly connected to the slide box containing the sample slide 108, and drives the slide box to move; the sixth motor 507 is fixedly connected to the body frame 8 through a bracket, and drives the horizontal injection lever 510 to move through a synchronous belt; the horizontal injection lever 510 is rotationally connected to the sixth motor 507, and is fixedly connected to the sample slide 108, and drives the sample slide 108 to move horizontally; the sample output component 14 cooperates with the sample input and output tray 503, and drives the sample slide 108 to move.
[0043] Further, the sample output assembly 14 includes a seventh motor 512, a lateral sample output lever 517 and an eighth motor 515. The seventh motor 512 is fixedly connected to the body frame 8 through a bracket, and is rotationally connected to the bottom pull component 502 through a synchronous belt, and drives the bottom pull component 502 and the sample slide 108 to move; the lateral sample output lever 517 is rotationally connected to the body frame 8 through a bracket, and is connected to the sample slide 108 through the eighth motor 515; the eighth motor 515 is fixedly connected to the body frame 8 through a bracket, and is connected to the lateral sample output lever 517 through a synchronous belt, and drives the lateral sample output lever 517 and the sample slide 108 to move.
[0044] In this embodiment, the sheet pusher and drying device 3 includes two L-shaped fixed foot blocks 301 on the sheet pusher support unit, the horizontal surface of the L-shaped fixed foot blocks 301 is fixed on the bottom plate frame 801, and the vertical surface is connected to the sheet pusher main support plate 302. Two sheet pusher reinforcement fixing plates 305 are installed on the side of the sheet pusher main support plate 302 different from the fixed foot blocks 301 and close to the upper surface, and the other end of the sheet pusher reinforcement fixing plate 305 is fixed on the control circuit support plate 805. The sheet pusher unit is fixed on the side of the sheet pusher main support plate 302 different from the sheet pusher reinforcement fixing plate 305. The sheet pusher unit includes the transverse screw motor 304 connected to the sheet pusher main support plate 302 through the transverse motor support plate, and the longitudinal translation unit connected to the transverse guide rail slider 303. The transverse screw motor uses the guide rail plus slider to realize the transverse movement of the pusher. The longitudinal translation unit mainly includes a longitudinal motor support plate 306 and a longitudinal screw motor 307 installed on the longitudinal motor support plate 306, and a push knife rotating unit 30 connected to the longitudinal guide rail slider 308. The longitudinal screw motor realizes the longitudinal movement of the push knife 310 by means of a guide rail plus a slider. The push knife rotating unit 30 includes a direct push motor 309 and the push knife 310. The direct push motor realizes the rapid adjustment of the push knife angle by pushing the push knife adjustment plate. The transverse screw motor 304 uses a large lead motor to obtain a higher lateral movement speed, and is combined with the transverse guide rail slider 303 and its slider parallel to the screw rod to fully ensure the stability of the lateral movement, thereby ensuring the verticality of the push knife, thereby ensuring high-quality blood film. The longitudinal screw motor 307 uses a small lead and high current motor, which can meet the motor movement speed requirements while ensuring that the distance between the push knife 310 and the sample glass slide 108 is subdivided, thereby ensuring the continuity and efficiency of the push slice. At the same time, the push knife obtains better and smoother transmission performance by adopting the transmission method of the screw motor plus the high-precision guide rail, thereby ensuring high-quality blood film. The direct push motor 309 uses a large thrust motor, and is combined with a tension spring structure to achieve flexible floating adjustment. At the same time, the material of the push knife 310 is preferably a sapphire material with high strength, good wear resistance, and convenient for blood film diffusion. When the sample on the sample slide 108 is contacted and diffused by the push knife 310, the camera 113 installed on the L-shaped loading mounting base plate 101 is used to record the sample diffusion time, and the program algorithm is used to record the sample diffusion time, so as to achieve the purpose of detecting the sample concentration, and then the sample concentration information or the HCT value obtained by the five-classification instrument is fed back to the control system, and a signal is sent to control the parameters such as the push knife speed, so as to realize the function of adaptively adjusting the blood film parameters of different samples.The sample slide 108 stops at the slide pushing position as the slide flipping platform 114, and the control circuit and the information processing device 6 send a signal to make the direct push motor 309 push the push knife 310 to rotate to a suitable angle, and then the horizontal screw motor 304 drives the push unit to move left to just above the sample, and then controls the longitudinal screw motor 307 to move down until the push knife 310 contacts and diffuses the sample on the sample slide 108, and then controls the horizontal screw motor 304 to continue to move left to complete the blood film pushing action. After the blood film is pushed, the blood film is pushed by the injection device installed on the injection device. The blood film drying fan on the device support plate 804 dries the blood film, and at the same time, the push knife 310 is moved to the push knife cleaning tank 311 installed on the bottom plate frame 801 for cleaning. The push knife cleaning tank 311 includes a cleaning port and a drying port respectively distributed on its left and right sides. The cleaning port is located below the drying port. After the push knife is cleaned, a high-pressure air pump is used to let the dry air flow enter from the drying port and discharge from the discharge port, and the push knife is dried through the push knife drying and wiping device 312, which is convenient for the next sample pusher. While ensuring cleanliness and preventing sample cross contamination, the push knife can be reused. The staining and liquid circuit support device 4 includes the glass slide clamping assembly 41 and the staining and liquid circuit support unit 42; the glass slide clamping assembly 41 mainly includes a clamping base 401 installed on the front support plate 802, and a horizontal translation motor 402 is fixed on the left side of the clamping base 401. The horizontal translation motor 402 uses a synchronous belt to make the longitudinal translation components and mechanical claws fixed on the horizontal translation guide rail and the slider 403 move back and forth left and right. The longitudinal translation component includes a longitudinal translation support 404 installed on the transverse translation guide rail and the slider 403, and a longitudinal translation motor 405 is fixed above the longitudinal translation support 404. The longitudinal translation motor 405 uses a synchronous belt to make the mechanical claw motor 407 fixed on the longitudinal translation guide rail and the slider 406 move up and down. The mechanical claws 408 are respectively installed on the left and right sides of the clamping end of the mechanical claw motor 407 to achieve the clamping action of the sample glass slide 108. The dyeing and its liquid circuit support unit mainly include the dyeing tank 409 fixed on the bottom plate frame 801 and the syringe, solenoid valve, pump and other components installed on the syringe support plate. The dyeing liquid and the cleaning liquid are pumped into the dyeing tank through the liquid circuit support component, so as to achieve the dyeing of the sample glass slide 108 and form a more complete blood smear. After the blood film on the sample slide 108 is dried, the fourth motor 117 transfers the sample slide 108 on the slide flipping platform to directly below the slide clamping assembly 41. The slide clamping assembly 41 then transfers the sample slide 108 to six staining channels for staining.The mechanical claw 408 mounted on the mechanical claw motor 407 is fixed with a photosensitive sensor, or a closed-loop feedback structure is formed inside the mechanical claw motor 407, so as to determine whether the sample glass slide 108 has been clamped, and the clamping force can be controlled to prevent the sample glass slide 108 from being broken due to excessive clamping or the sample glass slide 108 from being unable to be clamped due to insufficient clamping. Six or more staining channels are arranged on the staining and its liquid path support unit, so as to facilitate the fast and effective processing of the staining of the sample glass slide 108, thereby improving the preparation speed of the blood smear. The sample output connection bridge device 5 includes an L-shaped connecting bottom plate 501 for connecting the bottom plate frame 801 and the sample inlet and outlet channels, and a U-shaped motor support plate 504 is fixed on the L-shaped connecting bottom plate 501. The sample inlet and outlet tray 503 and the channel partition block 519 fixed on the U-shaped motor support plate 504 form four sample inlet and outlet channels for the slide box and the sample glass slide 108. The fifth motor 505 is fixed on the left vertical surface of the U-shaped motor support plate 504. When the infrared radiation sensor 506 respectively installed on the sample inlet and outlet tray 503 and the horizontal sample inlet support plate 508 detects the existence of an empty glass slide box 518 in the longitudinal sample inlet channel, the sample outlet control component 513 installed on the vertical surface of the L-shaped connecting bottom plate 501 sends a signal, so that the fifth motor 505 drives the bottom shifting component 502 to move back and forth through the synchronous belt, guide rail and slider, thereby realizing the longitudinal sample inlet action of the empty glass slide box 518. A lateral injection support plate 508 is fixed on the rear side of the L-shaped connecting base plate 501, and the sixth motor 507 is fixed on the left side of the lateral injection support plate 508. When the first sensor 509 installed on the lateral injection support plate 508 detects that the empty glass slide box 518 enters the lateral injection channel, the sample output control component 513 sends a signal, so that the sixth motor 507 drives the lateral injection lever 510 to move to the left through the synchronous belt, guide rail and slider, thereby realizing the lateral injection action of the empty glass slide box 518. The seventh motor 512 is fixed on the right vertical surface of the U-shaped motor support plate 504. When the second sensor 511 installed on the U-shaped motor support plate 504 detects that the empty slide box 518 enters the longitudinal sample output channel, the sample output control component 513 sends a signal, so that the seventh motor 512 drives the bottom shifting component 502 to move forward through the synchronous belt plus guide rail and its slider, thereby driving the slide box 518 to move forward to the working area, waiting for the blood smear to be placed in the slide box 518. After the slide box is full of slides, the seventh motor 512 continues to drive the slide box and the slides to move forward to the horizontal sample output channel.A transverse sample discharging support plate 516 is installed on the front side of the L-shaped connecting bottom plate, and the eighth motor 515 is connected and installed on the bottom plate frame 801. When the slide box with slides moves to the transverse sample discharging channel, under the control of the sample discharging control component 513, the eighth motor 515 drives the transverse sample discharging lever 517 to move leftward through the synchronous belt plus guide rail and slider, thereby completing the sample discharging action of the slide box and the sample slide 108; the user can place an empty slide box 518 at any position on the longitudinal sample feeding channel, and the longitudinal sample feeding channel has 9 empty slide box positions reserved, and the number of the reserved empty slide box positions can be increased as the length of the sample feeding and discharging tray 503 increases. A third sensor 514 is fixed on the right side of the U-shaped motor support plate 504 near the working area, which is used to detect whether the empty slide box 518 has reached the working area, and can also ensure the movement position accuracy of the slide box 518 to a certain extent, so as to wait for the smooth reception of the sample slide 108. A drying fan is fixed obliquely above the working area of the longitudinal sample discharge channel to facilitate drying of the sample blood smear after staining. After the blood smear preparation is completed, the sample discharge connection bridge device can be used to complete the online action with the automatic film reader, further improving the linkage of the fully automatic slide staining machine, thereby achieving a higher inspection speed and making the blood smear preparation more efficient.
[0045] What is disclosed above is only a preferred embodiment of the present invention, and it certainly cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiment and equivalent changes made according to the claims of the present invention still fall within the scope of the invention.
Claims
1. A fully automatic slide staining machine capable of continuous sample introduction and used for blood smear preparation, characterized in that: It includes a body frame, a sample slide, a slide loading and flipping device, a sampling and liquid circuit support device, a slide pushing and drying device, a staining and liquid circuit support device, a sample connection bridge device, a control circuit and an information processing device and a display device; The sample glass slide is slidably connected to the glass slide loading and flipping device and is located on the surface of the glass slide loading and flipping device. The glass slide loading and flipping device is fixedly connected to the body frame and connected to the sample glass slide through a bracket. The sampling and liquid circuit support device is fixedly connected to the body frame and cooperates with the glass slide loading and flipping device and is close to the sample glass slide. The slide pushing and drying device is fixedly connected to the body frame and cooperates with the sampling and liquid circuit support device. The staining and liquid circuit support device is fixedly connected to the body frame and cooperates with the slide pushing and drying device and faces the direction of the sample glass slide. The sample output connection bridge device is fixedly connected to the body frame and cooperates with the staining and liquid circuit support device. The sample glass slide is placed in a glass slide box and is slidably connected to the sample output connection bridge device through the glass slide box. The control circuit and information processing device are fixedly connected to the body frame, receive detection signals, and send operation signals. The display device is fixedly connected to the body frame and controls the control circuit and information processing device. The slide loading and flipping device comprises a slide loading slide, a slide lever, a slide flipping platform and a driving assembly. The slide loading slide is fixedly connected to the body frame and drives the sample slide to slide through the driving assembly. The slide lever is rotatably connected to the slide loading slide through a bracket and abuts against the sample slide and drives the sample slide to slide. The slide flipping platform cooperates with the slide loading slide and transports the sample slide through the driving assembly and flips under the drive of the driving assembly. The sampling and liquid circuit support device includes a sampling motor, a sample dropping motor and a liquid circuit cleaner. The sampling motor is fixedly connected to the body frame and controls the sampling needle to approach the serum sample. The sample dropping motor is fixedly connected to the body frame and controls the up and down movement of the sample dropping needle toward the direction of the sample slide. The liquid circuit cleaner is fixedly connected to the body frame and cooperates with the sampling motor and the sample dropping motor to complete the sampling and sample dropping actions and clean the sampling and sample dropping pipelines. The driving assembly includes a first motor, a second motor, a third motor and a fourth motor. The first motor is fixedly connected to the machine frame through a bracket and is extended and retracted toward the direction of the slide loading slide. The second motor is connected to the slide lever through a conveyor belt and drives the slide lever to push out the sample slide. The third motor is connected to the slide flipping platform through a coupling and drives the slide flipping platform to flip through an output shaft. The fourth motor is fixedly connected to the machine frame through a bracket and drives the third motor and the slide flipping platform to move toward the slide pushing and drying device. The slide loading and flipping device mainly comprises an L-shaped loading installation base plate and a slide loading component and a slide flipping component installed on the L-shaped loading installation base plate. The slide loading and flipping device is fixed to the base plate frame through the L-shaped loading installation base plate. A left support plate for slide loading and a right support plate for slide loading are respectively fixed on the left and right sides of the L-shaped loading installation base plate. A left slide loading slide and a right slide loading slide for slide loading guide are respectively installed on the support plates. The first motor is installed on the vertical surface of the L-shaped loading installation base plate near one end of the instrument screen. The motor nut is connected to the loading slide box by using an L-shaped folding plate. A smooth movement structure of a guide rail plus a slider is adopted to realize loading of slides. When the first detector detects that there is no glass slide in the loaded glass slide box and sends this signal to the control circuit board, the control circuit board sends a signal to make the first motor extend, and after enough glass slides are added, the first motor retracts again. At this time, after the first detector detects the sample glass slide information, the control circuit board controls the second motor to rotate forward, and drives the glass slide lever to move through the belt plus guide rail plus slider. The glass slide lever pushes out the bottom glass slide in the loaded glass slide box, thereby realizing the loading of the sample glass slide; after the previous glass slide is loaded, the next sample glass slide will fall naturally under the action of gravity, thereby realizing the glass slide. Continuous loading and sampling; a radio frequency card tag is attached to the sample slide for storing sample related information; a radio frequency circuit board is fixed to the right support plate for slide loading through a radio frequency circuit board connecting plate; when the sample slide is loaded to a certain position, the sample information on the sample slide is read through the radio frequency circuit board for querying and tracking the running sample, while ensuring the reliability of consistent sample information; when the blood dripping on the sample slide is completed, the second motor continues to drive the slide lever forward through the belt, guide rail and slider until the sample slide is pushed to the slide flipping platform, at which time the slide flipping platform is in a horizontal position, and the sample slide is held by a spring clip The slide flipping platform is fixed so that the sample can complete the blood film pushing action on the slide flipping platform; the slide flipping platform is connected to the third motor through a shaft plus a flexible coupling, and is fixedly installed on the guide rails of the horizontal surface of the L-shaped loading installation base plate through sliders, and the horizontal or vertical position flipping action of the slide flipping platform is completed by the forward and reverse rotation of the third motor; after the sample slide is pushed to the slide flipping platform, the fourth motor installed on the vertical surface of the L-shaped loading installation base plate close to the control circuit and one end of the information processing device is used to move the third motor and the slide flipping platform toward the slide pushing and drying device until the sample slide reaches the specified slide pushing position; The sampling and liquid circuit support device includes a sampling component and a sample dropping component. The sampling component includes the sampling motor, and the sample dropping component includes the sample dropping motor. The sampling motor is fixed on the front support plate. The sampling motor controls the up and down movement of the sampling needle to realize the extension and retraction of the sampling needle. The sample dropping motor is fixed on the bottom plate frame. The liquid circuit cleaner mainly consists of 2 syringes, 1 liquid displacement pump, and 8 solenoid valves as control units. The two syringes in the liquid circuit cleaner respectively use large-displacement and micro-injections. The large-displacement syringe is combined with the micro-injection syringe to realize rapid sampling and liquid circuit cleaning actions, and the micro-injection syringe realizes micro-sample dropping actions; V5, V The two solenoid valves are respectively clamp valves to achieve rapid response of sampling and dripping and effective control of liquid flow, and are convenient for cleaning. After the radio frequency circuit board detects the slide information on the sample slide, the signal is transmitted to the control circuit and the information processing device, and a signal is promptly sent to the second motor to push the sample slide to the blood dripping position, and a signal is simultaneously sent to the liquid circuit cleaner to complete the sample sampling and dripping actions. After the sample is dripped onto the sample slide, the sampling needle and the dripping needle and their pipelines are cleaned in time, and the dripping needle is controlled by the dripping motor to move up and down to realize the extension and retraction of the dripping needle, so that fully automatic sampling, dripping and liquid circuit cleaning actions can be realized.
2. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation according to claim 1, characterized in that: The slide pushing and drying device comprises a transverse translation unit, a longitudinal translation unit and a push knife rotating unit. The transverse translation unit is slidably connected to the machine frame via a bracket, and drives the longitudinal translation unit to slide transversely via a guide rail; the longitudinal translation unit is slidably connected to the machine frame via a bracket, and drives the push knife rotating unit to slide longitudinally via a guide rail; the push knife rotating unit abuts against the sample glass slide and slides on the surface of the sample glass slide.
3. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation as claimed in claim 2, characterized in that: The transverse translation unit includes a transverse screw motor and a transverse guide rail slider. The transverse screw motor is fixedly connected to the body frame through a bracket, and is connected to the transverse guide rail slider, and drives the transverse guide rail slider to slide; the transverse guide rail slider is rotationally connected to the transverse screw motor and is connected to the longitudinal translation unit to complete the left and right movement of the longitudinal translation unit, thereby realizing the left and right movement of the push knife rotating unit and completing the sheet pushing action.
4. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation as claimed in claim 3, characterized in that: The longitudinal translation unit includes a longitudinal screw motor and a longitudinal guide rail slider. The longitudinal screw motor is fixedly connected to the body frame through a bracket, and is connected to the longitudinal guide rail slider, and drives the longitudinal guide rail slider to slide; the longitudinal guide rail slider is connected to the longitudinal screw motor and to the push knife rotating unit to complete the up and down movement of the push knife rotating unit.
5. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation as claimed in claim 4, characterized in that: The staining and liquid path support device includes a glass slide clamping assembly and a staining tank. The glass slide clamping assembly is slidably connected to the body frame through a bracket, and is fixedly connected to the sample glass slide, and drives the sample glass slide into the staining tank; the staining tank is fixedly connected to the body frame, and is connected to the liquid path cleaner through a conduit.
6. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation as claimed in claim 5, characterized in that: The glass slide clamping assembly includes a clamping drive component, a mechanical claw motor and a mechanical claw. The clamping drive component is slidably connected to the body frame through a bracket, and drives the mechanical claw motor and the mechanical claw to move; the mechanical claw motor is slidably connected to the body frame through the clamping drive component, and drives the mechanical claw to move; the mechanical claw is fixedly connected to the mechanical claw motor, and clamps the sample glass slide.
7. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation according to claim 6, characterized in that: The clamping drive component includes a transverse translation motor and a longitudinal translation motor. The transverse translation motor is slidably connected to the body frame through a bracket, and drives the longitudinal translation motor to slide through a synchronous belt; the longitudinal translation motor is slidably connected to the transverse translation motor through a guide rail, and is connected to the mechanical claw motor through a synchronous belt, and drives the mechanical claw motor to slide.
8. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation according to claim 7, characterized in that: The sample output connection bridge device includes a sample input and output tray, a fifth motor, a bottom dial component, a sixth motor, a horizontal sample input lever and a sample output assembly, wherein the sample input and output tray is fixedly connected to the body frame and is slidably connected to the sample slide; the fifth motor is fixedly connected to the body frame through a bracket, and drives the bottom dial component to move through a synchronous belt, and drives the slide box containing the sample slide to slide; the bottom dial component is connected to the fifth motor, and is fixedly connected to the slide box containing the sample slide, and drives the slide box to move; the sixth motor is fixedly connected to the body frame through a bracket, and drives the horizontal sample input lever to move through a synchronous belt; the horizontal sample input lever is rotationally connected to the sixth motor, and is fixedly connected to the sample slide, and drives the sample slide to move horizontally; the sample output assembly cooperates with the sample input and output tray, and drives the sample slide to move.
9. The fully automatic slide-pushing and staining machine capable of continuous sample introduction and used for blood smear preparation according to claim 8, characterized in that: The sample output assembly includes a seventh motor, a transverse sample output lever and an eighth motor. The seventh motor is fixedly connected to the body frame through a bracket, and is rotatably connected to the bottom output component through a synchronous belt, and drives the bottom output component and the sample slide to move; the transverse sample output lever is rotatably connected to the body frame through a bracket, and is connected to the sample slide through the eighth motor; the eighth motor is fixedly connected to the body frame through a bracket, and is connected to the transverse sample output lever through a synchronous belt, and drives the transverse sample output lever and the sample slide to move.
Citation Information
Patent Citations
Full-automatic slide pushing dyeing machine capable of continuously feeding samples and used for blood smear preparation
CN212321232U