Intelligent biological specimen safe collection and processing system and control method

Abstract

The present invention discloses an intelligent biological specimen safety collection and processing system. The system is provided with a constant temperature box, and at least one group of sampling mechanisms is arranged in the constant temperature box. The advantage of the present invention is that it has a high degree of automation, and medical personnel can complete sample acquisition without contacting patients. The samples will be processed in the system and the viruses will be inactivated, so that subsequent laboratory testing work will not cause external pollution or infection.

Description

Technical Field

[0001] The invention relates to the field of medical testing equipment. Background Art

[0002] At present, clinical analysis and examination of sputum and other body fluid specimens is an indispensable medical activity for clarifying the cause of disease and monitoring the condition. The collection and processing of specimens by clinicians and doctors in medical technology departments are related to the test results of specimens.

[0003] Currently, most sample collection requires on-site collection by medical staff. If the sample collected is contagious, even if the medical staff wear protective clothing, there is still a risk of infection, and it will also increase the consumption of protective supplies in the hospital. Summary of the invention

[0004] The technical problem to be solved by the present invention is to realize a system capable of automatically completing the collection of biological specimens.

[0005] In order to achieve the above-mentioned object, the technical solution adopted by the present invention is: an intelligent biological specimen safety collection and processing system, the system is provided with a constant temperature box, and at least one set of sampling mechanisms is provided in the constant temperature box;

[0006] The sampling mechanism includes an electric cylinder fixed on the top of the thermostatic box, a bracket located inside the thermostatic box and connected to the telescopic rod of the electric cylinder, a clip fixed on the bracket, a collector, a fixing clip fixed on the inner wall of the thermostatic box for clamping the collector shell, a sampling three-way valve connected to the sample inlet of the collector through a hose, and a sample outlet three-way valve connected to the sample outlet of the collector through a hose, one interface of the sampling three-way valve is connected to the cleaning pipe row through a hose, and the other interface is connected to the hose extending to the outside of the thermostatic box for sampling, one interface of the sample outlet three-way valve is connected to the cleaning pipe row through a hose, and the other interface is connected to the hose extending to the outside of the thermostatic box for sampling, and the water inlet of the cleaning pipe row is connected to the cleaning pump through a pipeline;

[0007] The shell of the collector is a cylindrical hollow structure, one end of the shell is provided with an end cover, and the other end is sealed by a back cover. A piston is provided in the shell, and the rear end of the piston is connected to one end of the push rod. A guide hole is provided in the center of the back cover, and the other end of the push rod extends out of the shell through the guide hole and is connected to the push handle. A waste liquid outlet is provided on the end cover, and the waste liquid outlet is sealed by a sealing cover. A partition is provided near the front end of the shell, and the partition is a grid-shaped plate. A first filter membrane is fixed on the partition, and protruding sample ports are provided on the shells on both sides of the partition. A sponge layer is fixed on the piston, and the clamp on the bracket clamps the push rod, and the axis of the shell is parallel to the axis of the telescopic rod of the electric cylinder.

[0008] A specimen chamber and sampling chambers having the same number as the sampling mechanisms are provided at the bottom of the constant temperature box. Each of the sampling hoses extends into one of the sampling chambers, and each of the sample outlet hoses extends into the specimen chamber. A waste liquid collection tank is provided below the waste liquid outlet of the collector and is placed at the bottom of the constant temperature box.

[0009] A temperature sensor and a temperature control mechanism for heating or cooling are arranged in the constant temperature box. The temperature sensor outputs a signal to a controller of the system, and the controller outputs a control signal to the temperature control mechanism.

[0010] The controller is connected to the cleaning pump via a signal line, and the controller is connected to the electric cylinder, sampling three-way valve, and sample outlet three-way valve of the group sampling mechanism via a signal line. The outer surface of the constant temperature box is provided with a touch screen, a camera, and a speaker, and the touch screen, camera, and speaker are all connected to the controller via signal lines.

[0011] A sponge layer is also provided on the side of the partition facing the rear cover, and the sponge layer is filled with a solution for pre-treating the collected samples.

[0012] The end cover is a grid-shaped plate, the first filter membrane is fixed on the partition plate facing the rear cover, the sponge layer on the partition plate is fixed on the first filter membrane, and the end cover is provided with a second filter membrane on the side facing the partition plate, and the pores of the first filter membrane are larger than the pores of the second filter membrane.

[0013] Control method based on the intelligent biological specimen safety collection and processing system:

[0014] Sampling control method:

[0015] Step 1: After the sampling start signal is triggered, the speaker emits a prompt sound;

[0016] Step 2: After the sampling signal is triggered, the sampling three-way valve connects the sample inlet with the hose used for sampling;

[0017] Step 3, drive the electric cylinder to pull up the push rod to set the stroke;

[0018] Sample control method:

[0019] Step 1: After the sample signal is triggered, the speaker emits a prompt sound;

[0020] Step 2: After the sample output signal is triggered, the sampling three-way valve makes the sample inlet sealed, and the sample output three-way valve connects the sample outlet with the hose used for sample output;

[0021] Step 4: Drive the electric cylinder to push the push rod downward to set the stroke.

[0022] Also includes hose cleaning control methods:

[0023] Step 1: Pull the hose used for sampling off from the sample inlet, and place the end of the hose into the waste liquid collection tank; pull the hose used for discharging the sample off from the sample outlet, and place the end of the hose into the waste liquid collection tank;

[0024] Step 2: placing a cleaning cup in each sampling chamber and specimen chamber, and placing the end of the hose in the sampling chamber and specimen chamber into the cleaning cup;

[0025] Step 3: Pour cleaning liquid into the cleaning cup and the waste liquid collection tank;

[0026] Step 4: Start the cleaning pump to suck out the cleaning liquid in the cleaning cup and the waste liquid collection tank;

[0027] Step 5: Return to step 3 and repeat the cycle for the set number of times.

[0028] The advantage of the present invention is that it has a high degree of automation. Medical personnel can complete sample acquisition without contact with patients. The samples will be processed in the system and the viruses will be inactivated, so that subsequent laboratory tests will not cause external contamination or infection. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] The following is a brief description of the contents expressed in each figure in the specification of the present invention and the marks in the figure:

[0030] Figure 1 The schematic diagram of the intelligent biological specimen safe collection and processing system;

[0031] Figure 2 A schematic diagram of the structure of a collector used in conjunction with the intelligent biological specimen safety collection and processing system;

[0032] The markings in the above figures are: 1. push handle; 2. push rod; 3. piston; 4. sponge layer; 5. first filter membrane; 6. partition; 7. second filter membrane; 8. end cover; 9. waste liquid cup; 10. waste liquid outlet; 11. sample outlet; 12. sample inlet; 13. outer shell; 14. guide hole; 15. back cover; 16. sealing cover; 17. constant temperature box; 18. waste liquid collection tank; 19. fixing clamp; 20. electric cylinder; 21. sampling chamber; 22. cleaning tube row; 23. cleaning pump; 24. specimen chamber; 25. sampling three-way valve; 26. sample outlet three-way valve. DETAILED DESCRIPTION

[0033] The following is a further detailed description of the specific implementation methods of the present invention, such as the shape, structure, relative position and connection relationship between the various components involved, the function and working principle of each part, the manufacturing process and operation method, etc., through the description of the embodiments with reference to the accompanying drawings, so as to help those skilled in the art to have a more complete, accurate and in-depth understanding of the inventive concept and technical solution of the present invention.

[0034] The intelligent biological specimen safety collection and processing system is provided with a thermostatic box 17, which is a sealed box with a heat preservation layer filled in the box wall. The thermostatic box 17 is provided with a temperature sensor and a temperature control mechanism for heating or cooling, which constitutes a mechanism capable of maintaining the temperature in the box at a set temperature. The temperature sensor outputs a signal to the system controller, and the controller outputs a control signal to the temperature control mechanism. The controller obtains the temperature in the box and controls the temperature control mechanism to heat or cool, so as to provide a constant temperature storage environment for the sample. A box door is provided on one side of the thermostatic box 17, and the box door opening size is relatively large, so that it is convenient for the staff to place the collector.

[0035] At least one set of sampling mechanisms is provided in the thermostatic box 17. The sampling mechanisms are used to independently collect a set of samples. Each set of sampling mechanisms has the same structure and is fixed side by side in the thermostatic box 17. The number of sampling mechanisms can be designed according to the size of the thermostatic box 17. Figure 1 As shown, the sampling mechanism is provided with an electric cylinder 20 fixed on the top of the constant temperature box 17, the body of the electric cylinder 20 is fixed outside the constant temperature box 17, the telescopic rod vertically extends to the inside of the constant temperature box 17, a bracket is fixed on the telescopic rod, and a clamp for clamping the collector push rod 2 is provided on the bracket. The axis of the collector housing 13 is parallel to the axis of the telescopic rod of the electric cylinder 20. In this way, when the clamp clamps the push rod 2, the push rod 2 can be driven up and down by the electric cylinder 20 to realize sampling and sample output.

[0036] A fixing clamp 19 is also provided on the inner wall of the thermostat 17. The fixing clamp 19 is used to clamp the housing 13 of the sampler. Each sampling structure is provided with a sample outlet three-way valve 26 and a sampling three-way valve 25. Both valves are solenoid valves, and the conduction state of the solenoid valve can be driven by the controller. The three interfaces of the sampling three-way valve 25 are connected to the sample inlet 12 of the collector through a hose, connected to the cleaning pipe row 22 through a hose, and connected to the hose extending to the outside of the thermostat 17 for sampling. The three interfaces of the sample outlet three-way valve 26 are connected to the sample outlet 11 of the collector through a hose, connected to the cleaning pipe row 22 through a hose, and connected to the hose extending to the outside of the thermostat 17 for sample outlet. The cleaning pipe row 22 is a pipeline with multiple interfaces. The water inlet of the cleaning pipe row 22 is connected to the cleaning pump through a pipeline. The cleaning pump pumps water, and the cleaning agent can pass through the hose and the solenoid valve to clean the inner wall of the hose and the solenoid valve, so as to avoid interference with the next use and prevent virus spread.

[0037] The bottom of the thermostat 17 is provided with a specimen chamber 24 and sampling chambers 21 having the same number as the sampling mechanism. Each hose for sampling extends into one of the sampling chambers 21, and each hose for discharging samples extends into the specimen chamber 24. A waste liquid collection tank 18 placed at the bottom of the thermostat 17 is provided below the waste liquid outlet 10 of the collector. The waste liquid outlet 10 is sealed by a sealing cover 16. When it is necessary to discharge the waste liquid in the sampler, it is only necessary to remove the sealing cover 16 and drive the electric cylinder 20 to push down, so that the remaining waste liquid in the sampler can be discharged to the waste liquid collection tank 18. The door of each sampling chamber 21 can be numbered or distinguished by different colors, so that the patient can open the corresponding door according to the prompt and extract the sample using the hose on the inner wall without the need for medical staff to operate. The specimen chamber 24 has a large number of hoses, and a mark can be attached to each hose with a number, so that the medical staff or the patient can discharge the sample in the corresponding hose into the prepared container.

[0038] The entire system can be connected to the cleaning pump through the controller via a signal line. The controller is connected to the electric cylinder 20, the sampling three-way valve 25, and the sample output three-way valve 26 of the group sampling mechanism through the signal line, so as to control the operation of the entire system. The outer surface of the constant temperature box 17 is provided with a touch screen, a camera and a speaker. The touch screen, the camera and the speaker are all connected to the controller via signal lines. The touch screen can be used to operate the trigger-related signals, the camera can be used for remote observation, and the speaker can emit a prompt sound.

[0039] like Figure 2 As shown, the collector has a cylindrical shell 13 with an end cover 8 at one end and a rear cover 15 sealed at the other end. A piston 3 is arranged in the shell 13, and the rear end of the piston 3 is connected to one end of a push rod 2. A guide hole 14 is arranged in the center of the rear cover 15. The other end of the push rod 2 extends out of the shell 13 through the guide hole 14 and is connected to the push handle 1. A waste liquid outlet 10 is arranged on the end cover 8, forming a structure similar to that of a syringe.

[0040] The waste liquid outlet 10 includes a connecting cover and a liquid outlet. One side of the connecting cover is an open side, and the other side is connected to the liquid outlet. The edge of the open side of the connecting cover is fixed on the shell 13. The waste liquid outlet 10 has a circle of snap-fit ​​structure outside, and a waste liquid cup 9 is mounted on the snap-fit ​​structure.

[0041] A partition 6 is provided near the front end of the outer shell 13, and a first filter membrane 5 is fixed on the partition 6. The pores of the first filter membrane 5 cannot allow large molecular viruses to pass through, but can allow decomposed small molecules to pass through. Protruding sample ports are provided on the outer shell 13 on both sides of the partition 6. The sample port on the outer shell 13 between the partition 6 and the end plate is a sample outlet 11 for discharging liquid, and the other sample port is a sample inlet 12 for inhaling liquid. A sealing cover 16 is provided on the waste liquid outlet 10, the sample outlet 11 and the sample inlet 12. The sample outlet 11 and the sample inlet 12 are equipped with a rubber hose that is connected when the sealing cover 16 is removed. The sealing cover 16 is preferably a threaded cover structure, which can avoid detachment when the push rod 2 is pressed down, and can also ensure air tightness.

[0042] A sponge layer 4 is fixed on the piston 3, and a sponge layer 4 is also provided on the side of the partition 6 facing the back cover 15. The thickness of the sponge layer 4 on the partition 6 is less than that of the sponge layer 4 on the piston 3. The sponge layer 4 on the piston 3 is filled with a pretreatment solution for pretreatment of the collected sample, and the pretreatment solution depends on the type of sample. The partition 6 and the end cover 8 are grid-shaped plates. The first filter membrane 5 is fixed on the partition 6 facing the back cover 15, and the end cover 8 is provided with a second filter membrane 7 on the side facing the partition 6, so that the partition 6 and the end cover 8 can support the filter membrane and prevent the filter membrane from falling off. The pores of the first filter membrane 5 are larger than the pores of the second filter membrane 7. The second filter membrane 7 can only allow water molecules to pass through, and the decomposed viruses cannot pass through, and remain in the processor, waiting for the unified treatment of medical waste in the future.

[0043] A card slot is provided on the push rod 2, in which a plug-in that can be selectively inserted or removed is embedded. When the plug-in is inserted into the card slot, it serves as a limit mechanism for pushing the push rod 2 into the shell 13. When the plug-in contacts the back cover 15, there is a gap between the two sponge layers 4 to avoid operation, pushing the push rod 2 to squeeze out the pretreatment solution in the sponge layer 4.

[0044] When installing the collector into the thermostat 17, remove the sealing cover, insert the corresponding hose into the sample outlet 11 and the sample inlet 12, use the fixing clamp 19 to clamp the housing 13, clamp the push rod 2 with the clamp, and remove the insert. In this operation mode, the first filter membrane cannot allow large molecular viruses to pass through, and can only pass through after the virus is inactivated and decomposed into small molecules, thus avoiding contamination; when coming out of the sampling area, the output liquid will not carry the acquired virus, and the second filter membrane can only filter out water molecules, and other toxic and harmful impurities will remain in the collector.

[0045] Control method based on the above intelligent biological specimen safety collection and processing system:

[0046] Sampling control method:

[0047] Step 1: Press a button displayed on the touch screen to trigger a sampling start signal, and the speaker emits a prompt sound, for example, the prompt sound is to open the second sampling chamber 21, put in a small cup, and put the hose into the small cup;

[0048] Step 2: After the user has placed the device, he presses a button displayed on the touch screen again to trigger a sampling signal. Then, the sampling three-way valve 25 connects the sample inlet 12 with the hose used for sampling.

[0049] Step 3, drive the electric cylinder 20 to pull up the push rod 2 to set the stroke, and use the sampler to absorb the quantitative sample;

[0050] After that, the user can be prompted to take away the small cup, put the small cup with the cleaning agent into the sampling chamber 21, and put the hose into the small cup;

[0051] Sample control method:

[0052] Step 1: Press a button displayed on the touch screen to trigger the sample output signal, and the speaker will emit a prompt sound. For example, the prompt sound indicates that the sample output hose is hose No. 2;

[0053] Step 2: Press a button displayed on the touch screen to trigger the sample output signal. The sampling three-way valve 25 seals the sample inlet 12, and the sample output three-way valve 26 connects the sample outlet 11 with the hose for outputting the sample. The staff needs to put the No. 2 hose in the sampling chamber 21 into the preset small cup.

[0054] Step 4: Drive the electric cylinder 20 to push the push rod 2 downward to set the stroke.

[0055] The above-mentioned sampling control method and sample output control method complete the automatic control process of sampling and sample output of one sampling mechanism, and other sampling mechanisms are controlled according to this method.

[0056] To avoid contamination, the system also has a hose cleaning control method:

[0057] Step 1, pull out the hose for sampling from the sample inlet 12, and place the end of the hose in the waste liquid collection tank 18, pull out the hose for discharging the sample from the sample outlet 11, and place the end of the hose in the waste liquid collection tank 18;

[0058] Step 2: Place a cleaning cup in each sampling chamber 21 and specimen chamber 24, and place the end of the hose in the sampling chamber 21 and specimen chamber 24 into the cleaning cup;

[0059] Step 3, pouring cleaning liquid into the cleaning cup and the waste liquid collecting tank 18;

[0060] Step 4, start the cleaning pump 23 to suck out the cleaning liquid in the cleaning cup and the waste liquid collection tank 18;

[0061] Step 5: Return to step 3 and repeat the cycle for the set number of times.

[0062] Flushing multiple times can ensure the cleanliness of the inside of the hose and minimize the impact on the next collection.

[0063] The present invention is described above by way of example in conjunction with the accompanying drawings. It is obvious that the specific implementation of the present invention is not limited to the above-mentioned method. As long as various non-substantial improvements are made using the method concept and technical solution of the present invention, or the concept and technical solution of the present invention are directly applied to other occasions without improvement, they are all within the protection scope of the present invention.

Claims

1. An intelligent biological specimen safe collection and processing system, characterized by: The system is provided with a constant temperature box, and at least one set of sampling mechanisms is provided in the constant temperature box; The sampling mechanism includes an electric cylinder fixed on the top of the thermostatic box, a bracket located inside the thermostatic box and connected to the telescopic rod of the electric cylinder, a clip fixed on the bracket, a collector, a fixing clip fixed on the inner wall of the thermostatic box for clamping the collector shell, a sampling three-way valve connected to the sample inlet of the collector through a hose, and a sample outlet three-way valve connected to the sample outlet of the collector through a hose, one interface of the sampling three-way valve is connected to the cleaning pipe row through a hose, and the other interface is connected to the hose extending to the outside of the thermostatic box for sampling, one interface of the sample outlet three-way valve is connected to the cleaning pipe row through a hose, and the other interface is connected to the hose extending to the outside of the thermostatic box for sampling, and the water inlet of the cleaning pipe row is connected to the cleaning pump through a pipeline; The shell of the collector is a cylindrical hollow structure, one end of the shell is provided with an end cover, and the other end is sealed by a back cover. A piston is provided in the shell, and the rear end of the piston is connected to one end of a push rod. A guide hole is provided in the center of the back cover, and the other end of the push rod extends out of the shell through the guide hole and is connected to a push handle. A waste liquid outlet is provided on the end cover, and the waste liquid outlet is sealed by a sealing cover. A partition is provided near the front end of the shell, and the partition is a grid-shaped plate. A first filter membrane is fixed on the partition. The shells on both sides of the partition are provided with protruding sample ports. A sponge layer is fixed on the piston, and the clamp on the bracket clamps the push rod. The axis of the shell is parallel to the axis of the telescopic rod of the electric cylinder. When sampling, the sampling three-way valve connects the sample inlet with the hose used for sampling; When discharging a sample, the sampling three-way valve makes the sample inlet into a sealed state, and the sample outlet three-way valve makes the sample outlet communicate with the hose used for discharging a sample.

2. The intelligent biological specimen safety collection and processing system according to claim 1 is characterized in that: A specimen chamber and sampling chambers having the same number as the sampling mechanisms are provided at the bottom of the constant temperature box. Each of the sampling hoses extends into one of the sampling chambers, and each of the sample outlet hoses extends into the specimen chamber. A waste liquid collection tank is provided below the waste liquid outlet of the collector and is placed at the bottom of the constant temperature box.

3. The intelligent biological specimen safety collection and processing system according to claim 2 is characterized in that: A temperature sensor and a temperature control mechanism for heating or cooling are arranged in the constant temperature box. The temperature sensor outputs a signal to a controller of the system, and the controller outputs a control signal to the temperature control mechanism.

4. The intelligent biological specimen safety collection and processing system according to claim 3 is characterized by: The controller is connected to the cleaning pump via a signal line, and the controller is connected to the electric cylinder, sampling three-way valve, and sample outlet three-way valve of the group sampling mechanism via a signal line. The outer surface of the constant temperature box is provided with a touch screen, a camera, and a speaker, and the touch screen, camera, and speaker are all connected to the controller via signal lines.

5. The intelligent biological specimen safe collection and processing system according to any one of claims 1 to 4, characterized in that: A sponge layer is also provided on the side of the partition facing the rear cover, and the sponge layer is filled with a solution for pre-treating the collected samples.

6. The intelligent biological specimen safety collection and processing system according to claim 5 is characterized in that: The end cover is a grid-shaped plate, the first filter membrane is fixed on the partition plate facing the rear cover, the sponge layer on the partition plate is fixed on the first filter membrane, and the end cover is provided with a second filter membrane on the side facing the partition plate, and the pores of the first filter membrane are larger than the pores of the second filter membrane.

7. A control method for the intelligent biological specimen safety collection and processing system according to any one of claims 1 to 6, characterized in that: Sampling control method: Step 1: After the sampling start signal is triggered, the speaker emits a prompt sound; Step 2: After the sampling signal is triggered, the sampling three-way valve connects the sample inlet with the hose used for sampling; Step 3, drive the electric cylinder to pull up the push rod to set the stroke; Sample control method: Step 1: After the sample signal is triggered, the speaker emits a prompt sound; Step 2: After the sample output signal is triggered, the sampling three-way valve makes the sample inlet sealed, and the sample output three-way valve connects the sample outlet with the hose used for sample output; Step 4: Drive the electric cylinder to push the push rod downward to set the stroke.

8. The control method according to claim 7, characterized in that: Also includes hose cleaning control methods: Step 1: Pull the hose used for sampling off from the sample inlet, and place the end of the hose into the waste liquid collection tank; pull the hose used for discharging the sample off from the sample outlet, and place the end of the hose into the waste liquid collection tank; Step 2: placing a cleaning cup in each sampling chamber and specimen chamber, and placing the end of the hose in the sampling chamber and specimen chamber into the cleaning cup; Step 3: Pour cleaning liquid into the cleaning cup and the waste liquid collection tank; Step 4: Start the cleaning pump to suck out the cleaning liquid in the cleaning cup and the waste liquid collection tank; Step 5: Return to step 3 and repeat the cycle for the set number of times.

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