Eyeball-motion-positioning-based proton-heavy ion beam current gate control method for eyeball tumor radiotherapy

An eye movement, heavy ion beam technology, applied in the field of radiological medicine, can solve the problems of affecting placement, affecting the proton heavy ion beam current range, affecting the proton heavy ion radiotherapy accuracy, etc., so as to reduce the impact, improve the treatment efficiency, reduce the The effect of the probability of operating errors

CN112691305AActive Publication Date: 2021-04-23上海市质子重离子医院有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2021-04-23

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Abstract

The invention discloses an eyeball-motion-positioning-based proton-heavy ion beam current gate control method for eyeball tumor radiotherapy. The method comprises the steps: acquiring real-time images of an eyeball by utilizing eyeball motion image acquisition equipment, carrying out pixel graduation by utilizing a diameter of an iris, carrying out analysis so as to obtain a real-time motion displacement curve of the eyeball, setting a position deviation threshold, outputting a gate control signal to a proton-heavy ion treatment system through a communication unit, and then, controlling interruption and recovery of a proton-heavy ion beam current. According to the method, gate control on eyeball motion during proton-heavy ion radiotherapy of a malignant tumor of the eyeball is achieved, and the beam current of a proton-heavy ion device is interrupted when a deviation between an eyeball position and a reference position reaches a certain threshold; and the beam current is recovered when the deviation between the eyeball position and the reference position is smaller than the threshold, so that accurate radiotherapy of intraocular tumors is achieved, and the therapy efficiency is increased.
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Description

technical field

[0001] The invention relates to the field of radiation medicine, in particular to a proton heavy ion beam gating method based on eyeball movement positioning in eyeball tumor radiotherapy. Background technique

[0002] Uveal malignant melanoma is a rare ocular malignancy, including choroidal melanoma, ciliary body melanoma, and iris melanoma. The incidence rate in Europe is 5-7 cases / year per million people, and the incidence rate in Asia is 0.4-0.6 cases / year per million people. The main treatment methods include enucleation, local excision, thermotherapy, photon radiotherapy, particle brachytherapy, and ion radiotherapy. Radiation therapy has become the main treatment for ocular malignant tumors. It has been reported in the literature that proton and heavy ion radiotherapy can provide better results in terms of tumor control, eye protection, vision and the incidence of adverse events.

[0003] During ion radiation therapy for malignant tumors of the eyeb...

Examples

Embodiment Construction

[0035] The present invention will be further described in detail below in conjunction with the accompanying drawings and examples. The following examples are explanations of the present invention and the present invention is not limited to the following examples.

[0036] see Figure 1-Figure 2 , the present embodiment relates to a proton heavy ion beam gating method based on eye movement positioning in eyeball tumor radiotherapy, comprising the following steps:

[0037] (1) Position the patient's head on the treatment bed with a jig. An LED point light source array is arranged above the eyeball. An image acquisition device is set on the top to continuously collect real-time images of eye movement, and the relative position between the image acquisition device and the patient's head remains fixed;

[0038] (2) Light up the LED lamp beads directly above the patient's eyeball for treatment, and the patient stares at the LED light directly above the eyeball, and the light source...