An expandable mobile biosafety laboratory

Abstract

The present invention provides an expandable mobile biosafety laboratory, including a front, a chassis and a carriage, wherein an amplification analysis area, a sample preparation area and a reagent preparation area are sequentially arranged in the carriage from the front to the rear; the amplification analysis area, the sample preparation area and the reagent preparation area are separated by a sealing partition; a first side drawer, a second side drawer and a third side drawer are sequentially arranged on one side of the carriage from the front to the rear; the first side drawer is located in the amplification analysis area, the second side drawer is located in the sample preparation area, and the third side drawer is located in the reagent preparation area; the first side drawer, the second side drawer and the third side drawer are all arranged to slide and pull with the carriage. Each area is separated separately and will not affect each other. By adding the first side drawer, the second side drawer and the third side drawer, the space of each area can be increased. When in use, each side drawer can be opened, and the retraction of each side drawer during the driving process of the vehicle will not affect the passability of the vehicle.

Description

Technical Field

[0001] The present invention and the technical field of biosafety testing equipment specifically relate to an expandable mobile biosafety laboratory. Background Art

[0002] The existing mobile biological laboratories are container-type, which requires a separate tractor to transport the containers, and they cannot be used at will. Due to the particularity of infectious diseases, high requirements are placed on each functional area. If a conventional carriage is directly divided into multiple areas, the space in each area is limited and sufficient equipment cannot be installed. Therefore, multiple vehicles are required to complete an experiment, which will make independent work difficult. Summary of the invention

[0003] The present invention provides an expandable mobile biosafety laboratory to solve the problem that currently container-type laboratories cannot be stopped and used at will or that multiple vehicles are used to meet experimental needs, resulting in low independent workability.

[0004] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0005] An expandable mobile biosafety laboratory comprises a front part, a chassis and a carriage, wherein the chassis is located at the rear of the front part, and the carriage is installed on the chassis, wherein an amplification analysis area, a sample preparation area and a reagent preparation area are sequentially arranged in the carriage from the front part to the rear; the amplification analysis area, the sample preparation area and the reagent preparation area are separated by a sealed partition; a first side pull-out box, a second side pull-out box and a third side pull-out box are sequentially arranged on one side of the carriage from the front part to the rear; the first side pull-out box is located in the amplification analysis area, the second side pull-out box is located in the sample preparation area, and the third side pull-out box is located in the reagent preparation area; the first side pull-out box, the second side pull-out box and the third side pull-out box are all arranged to slide and be pulled with the carriage.

[0006] Preferably, a fourth side pull-out box is provided on the side of the sample preparation area opposite to the second side pull-out box, and a side pull-out platform is provided on the side of the reagent preparation area opposite to the third side pull-out box; the amplification analysis area, the sample preparation area and the reagent preparation area are respectively provided with a first door, a second door and a third door; a biosafety cabinet is installed in the middle of the sample preparation area. The first door is installed on the side opposite to the first side pull-out box, and the second door and the third door are both entered from the side pull-out platform, so that the three areas are independent of each other. The side pull-out platform is pulled out when in use in the laboratory and can be retracted when not in use. The second side pull-out box and the fourth side pull-out box are respectively provided on both sides of the sample preparation area, so that the space of the sample preparation area can be increased, and the biosafety cabinet can be installed in the middle.

[0007] Preferably, a first boarding ladder is provided on a side of the amplification analysis area opposite to the first side-pull compartment; a second boarding ladder is provided on the side-pull platform, and the second boarding ladder is slidably connected to the side-pull platform.

[0008] Preferably, the amplification analysis area, sample preparation area and reagent preparation area are respectively provided with an amplification buffer area, a sample buffer area and a reagent buffer area. When a person first enters a corresponding area, he or she must first pass through the corresponding buffer area, where he or she can change clothes and disinfect, so that the person is sterile when entering the corresponding area.

[0009] Preferably, a sterilization zone is provided on one side of the amplification analysis zone near the sample preparation zone, and the sterilization zone is connected to the amplification buffer zone. By adding the sterilization zone, medical waste can be sterilized before being transported away.

[0010] Preferably, an equipment door is provided on the second side drawer. Since a biological safety cabinet is installed in the sample preparation area and it is impossible to enter or exit from the second door, an equipment door is provided on the second side drawer to facilitate the replacement of large equipment such as the biological safety cabinet.

[0011] Preferably, the reagent preparation area is provided with an air conditioner outside unit and a purification air conditioner main unit on the side away from the sample preparation area; a main air duct is provided on the top of the laboratory, and the main air duct is connected to the purification air conditioner main unit; the amplification analysis area, the sample preparation area, the reagent preparation area, the amplification buffer area, the sample buffer area, the reagent buffer area and the sterilization and disinfection area are all provided with purification air supply outlets, and each of the purification air supply outlets is connected to the main air duct through a branch air duct; each of the branch air ducts is connected to an air supply power module; an exhaust module is installed in the amplification buffer area, the sample buffer area and the reagent buffer area. The air intake in each area is independent, and the reagent preparation area requires a cleaner environment relative to the sample preparation area and the amplification analysis area. Therefore, the reagent preparation area is placed close to the purification air conditioner main unit, and each area is supplied with air through the air supply power module, and each buffer area is exhausted through the exhaust module.

[0012] Preferably, the amplification analysis area, sample preparation area and reagent preparation area are all provided with a water pool, and the sample buffer area and reagent buffer area are both provided with a hand washer. The hand washer is configured in the buffer area to disinfect hands, and the water pool is equipped in each functional area for convenient hand washing.

[0013] Preferably, there are transfer windows between the reagent preparation area and the sample preparation area, between the sample preparation area and the amplification analysis area, between the amplification analysis area and the sterilization area, and between the sterilization area and the sample preparation area, and there is also a transfer window on the wall of the fourth side drawer. The transfer window facilitates the transfer of reagent samples, etc., and also facilitates the transfer of waste to the sterilization area.

[0014] Preferably, support legs are provided under the chassis, and the support legs can provide support to the vehicle compartment when the vehicle is stopped.

[0015] Compared with the prior art, the present invention has the following beneficial effects: the present application divides the compartment into an amplification analysis area, a sample preparation area and a reagent preparation area, and each area is separated and will not affect each other, and by setting a first side pull-out compartment in the amplification analysis area, a second side pull-out compartment in the sample preparation area, and a third side pull-out compartment in the reagent preparation area, the space of each area can be increased, and the side pull-out compartments can be opened when in use, and the side pull-out compartments can be retracted during the driving of the vehicle without affecting the vehicle's passability. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 The interior layout of the expandable mobile biosafety laboratory provided for this application Figure 1 ;

[0017] Figure 2 The interior layout of the expandable mobile biosafety laboratory provided for this application Figure 2 ;

[0018] Figure 3 Left side view of the expanded mobile biosafety laboratory provided for this application;

[0019] Figure 4 Right side view of the expanded mobile biosafety laboratory provided for this application;

[0020] Figure 5 Rear view of the expanded mobile biosafety laboratory provided for this application;

[0021] Figure 6 for Figure 1 Sectional view of AA in the middle;

[0022] Figure 7 for Figure 1 Cross-sectional view of the middle BB;

[0023] Figure 8 for Figure 1 Sectional view of C1-C1;

[0024] Fig. 9 for Figure 1 a cross-sectional view of C2-C2;

[0025] Fig.10 Schematic diagram of the airflow of the expandable mobile biosafety laboratory.

[0026] Markings in the figure: 1-reagent preparation area, 2-sample preparation area, 3-amplification analysis area, 4-reagent buffer, 5-sample buffer, 6-amplification buffer, 7-sterilization area, 9-air conditioning area, 10-fourth side pull-out compartment, 11-third side pull-out compartment, 12-second side pull-out compartment, 13-first side pull-out compartment, 14-front of the vehicle, 15-side pull-out platform, 16-first door, 17-inner door, 18-transfer window, 19-first boarding ladder, 20-light-transmitting window, 21-workbench, 22-refrigerator, 23-nucleic acid extractor, 24-amplifier, 25-oven, 26- Biological safety cabinet, 27-second door, 28-computer, 29-third door, 30-air conditioner outdoor unit, 31-purification air conditioner main unit, 33-control cabinet, 34-mobile ultraviolet lamp, 35-purification exhaust vent, 36-laboratory bench, 37-sink, 38-second boarding ladder, 40-equipment door, 41-camera, 42-exterior lighting, 46-purification air supply vent, 48-laboratory table, 54-top ladder, 56-air supply power module, 57-locker, 59-hand wash basin, 75-support leg, 76-branch air duct, 77-main air duct, 78-exhaust module. DETAILED DESCRIPTION

[0027] The present invention will be described in detail below in conjunction with the accompanying drawings.

[0028] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0029] In the description of the present invention, it is necessary to understand that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0030] In the description of the present invention, unless otherwise specified and limited, it should be noted that the terms "installed", "connected" and "connected" should be understood in a broad sense. For example, it can be a mechanical connection or an electrical connection, or it can be the internal connection between two components. It can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms can be understood according to the specific circumstances.

[0031] like Figure 1As shown, the present application provides an expandable mobile biosafety laboratory, including a front 14, a chassis and a carriage, wherein the chassis is located at the rear of the front 14, and the carriage is installed on the chassis, and the carriage is provided with an amplification analysis area 3, a sample preparation area 2 and a reagent preparation area 1 in sequence from the front 14 to the rear; the amplification analysis area 3, the sample preparation area 2 and the reagent preparation area 1 are separated by a sealed partition.

[0032] One side of the carriage is provided with a first side drawer 13, a second side drawer 12 and a third side drawer 11 in sequence from the front 14 to the rear; the first side drawer 13 is located in the amplification analysis area 3, the second side drawer 12 is located in the sample preparation area 2, and the third side drawer 11 is located in the reagent preparation area 1. A fourth side drawer 10 is also provided on the side of the sample preparation area 2 opposite to the second side drawer 12, so that the sample preparation area 2 can be expanded by two measurement compartments. The first side drawer 13, the second side drawer 12, the third side drawer 11 and the fourth side drawer 10 are all arranged to slide and pull with the carriage.

[0033] An amplification buffer zone 6 and a sterilization zone 7 are provided on the side of the amplification analysis zone 3 away from the first side drawer 13, and a hand washer 59 is installed in the amplification buffer zone 6. A first door 16 is provided outside the amplification buffer zone 6, and a sliding first boarding ladder 19 is provided at the lower part of the first door 16. An inner door 17 is also provided between the amplification buffer zone 6 and the amplification analysis zone 3, and an inner door 17 is also provided between the sterilization zone 7 and the amplification buffer zone 6. The experimenter enters the amplification buffer zone 6 through the first boarding ladder 19 to change clothes and disinfect, and then enters the sterilization zone 7 or the amplification buffer zone 6 to work. A transfer window 18 is provided between the amplification analysis zone 3 and the sterilization zone 7, and an amplifier 24 and a computer 28 are installed in the first side drawer 13. A water pool 37, a laboratory table 48, a mobile ultraviolet lamp 34 and other equipment are provided in the amplification analysis zone 3. The first door 16 and the inner door 17 of the amplification buffer zone 6 are interlocked.

[0034] The amplification analysis area 3 is used to amplify the product, obtain the test results, and perform analysis. The amplification analysis area 3 is arranged at the rear of the cab. The door of the amplification buffer room is opened to enter the area. The inner door 17 can be opened only after the first door 16 is closed. A nucleic acid extractor equipment mounting bracket is provided in the amplification analysis area 3. The nucleic acid extractor can be pulled forward for use to ensure its heat dissipation. A power socket is provided on the wall for installing a nucleic acid extractor amplification detector. At the same time, 28 computers, air supply and exhaust vents, a transfer window 18 for transferring products and a transfer window 18 for transferring waste are provided, and a laboratory bench 36 is provided.

[0035] A sample buffer 5 is provided at the entrance of the sample preparation area 2, a biosafety cabinet 26 is installed in the middle of the sample preparation area 2, a plurality of nucleic acid extractors 23 are installed in the second side drawer 12, a water tank 37 is provided on the side of the sample preparation area 2 close to the reagent preparation area 1, and a refrigerator 22, an oven 25 and a computer 28 are provided in the fourth side drawer 10. An equipment door 40 is provided on the outer wall of the second side drawer 12, and large equipment such as the biosafety cabinet 26 can enter and exit through the equipment door 40, and a light-transmitting window 20 is provided on the equipment door 40. On the first side drawer 13 and the second side drawer 12, the sample preparation area 2 and the amplification analysis area 3 also transfer items through the transfer window 18, and a locker 57 can be provided at the lower part of the transfer window 18 to place items. A transfer window 18 is also provided on the outer wall of the fourth side drawer 10. A sample buffer 5 is provided at the entrance of the sample preparation area 2, and a hand-washing device 59 and a locker are installed in the sample buffer 5, so that clothes can be changed and disinfected before entering the sample preparation area 2.

[0036] The sample preparation area 2 is an area for processing the tested samples and is a key area for biological experiments. The sample preparation area 2 is located at the rear of the amplification analysis area 3. A widened equipment door 40 is provided on the left side of the vehicle in this area to facilitate the entry and exit of the equipment from this door; a second door 27 is provided on the right side of the vehicle, and the second door 27 of this area is connected to the side pull platform 15 at the rear. An oven 25, a biosafety cabinet 26, a nucleic acid extractor 23, a refrigerator 22, a workbench 21, a sink 37 and air supply and exhaust vents are installed inside the sample preparation area 2. In order to facilitate the transfer of reagents, samples, products and wastes, a reagent, sample, product and waste transfer window 18 is set, equipped with two laboratory benches 36, and a biosafety cabinet 26 is configured for sample processing.

[0037] A reagent buffer 4 is provided at the entrance of the reagent preparation area 1, and a hand-washing device 59 and a locker are provided in the reagent buffer 4. A side pull platform 15 is provided for sliding on the side of the reagent preparation area 1 away from the third side pull box 11, and a second boarding ladder 38 is provided for sliding at the bottom of the side pull platform 15. When the vehicle stops and needs to be used, the side pull platform 15 is pulled out, and then the second boarding ladder 38 is pulled out, and the amplification analysis area 3 and the sample preparation area 2 are entered through the second boarding ladder 38 and the side pull platform 15. A control cabinet 33, a laboratory bench 36 and a sink 37 are installed in the reagent preparation area 1, and a workbench 21 and a refrigerator 22 are installed in the third side pull box 11. On the side of the reagent preparation area 1 close to the third side pull box 11, a transfer window 18 is also provided between the reagent preparation area 1 and the sample preparation area 2, and a locker 57 is provided at the lower part of the transfer window 18.

[0038] An air conditioner outside unit 30 and a purification air conditioner main unit 31 are installed on the side of the reagent preparation area 1 away from the sample preparation area 2, and the purification air conditioner main unit 31 is connected to the air conditioner outside unit 30. A main air duct 77 is provided on the top of the laboratory, and the main air duct 77 is connected to the purification air conditioner main unit 31. Purification air supply ports 46 are provided in the amplification analysis area 3, the sample preparation area 2, the reagent preparation area 1, the amplification buffer area 6, the sample buffer area 5, the reagent buffer area 4 and the sterilization and disinfection area 7, and each of the purification air supply ports 46 is connected to the main air duct 77 through a branch air duct 76; each of the branch air ducts 76 is connected to an air supply power module 56; and exhaust modules 78 are installed in the amplification buffer area 6, the sample buffer area 5 and the reagent buffer area 4.

[0039] The reagent preparation area 1 is used for the preparation and storage of reagents. This area is at the rear of the sample preparation area 2. The reagent preparation area 1 is equipped with a side pull platform 15, a third door 29 and a second boarding ladder 38. The side pull platform 15 is also connected to the second door 27 of the sample preparation area to form a boarding passage to meet the needs of personnel entering and exiting. The reagent preparation area 1 is equipped with a workbench 21, a reagent refrigerator 22, a storage cabinet, a clean workbench 21, a purified air supply port 46 and an exhaust port, a transfer window 18 for transferring reagents, and a laboratory bench 36. This area is a non-contaminated area. The control cabinet 33 of the entire laboratory is installed in this area. The control cabinet 33 is equipped with a display control screen to monitor the environment, power and air conditioning of each area. Support legs 75 are provided under the chassis.

[0040] This equipment is a biosafety enhanced level 2 experiment after expansion, and a motor vehicle after folding. The main functional area is set in the middle of the vehicle and is divided according to functional requirements. The experimental areas in the middle of the vehicle from front to back are: amplification and analysis area, sample preparation area 2, reagent preparation area 1 three main working areas, three main areas are independently configured with three buffer zones, plus the disinfection and sterilization area, a total of seven functional areas. The front of the vehicle is the driving area, the air conditioning and power generation area is at the rear of the vehicle, the air conditioning area 9 is above the power generation area, and the lower part of the middle of the vehicle is the skirt cabin area, which is used to install cable trays, distribution boxes, water tanks, water pipes and other ancillary facilities. Reagent preparation area 1 is a clean area, close to the purification air conditioning main unit 31, sample preparation and amplification analysis area 3 is a contaminated area, which must be far away from the purification air conditioning main unit 31, and each functional area, driving area and air conditioning equipment area are completely isolated, and the functional areas have ventilation pressure difference control.

[0041] The upper right side of the vehicle is equipped with a camera 41 and an exterior lighting 42, and the lower part is a skirt door. The skirt is equipped with an additional fuel tank, a support leg 75, a backup battery, a clean water tank and the original vehicle fuel tank. Figure 3A sealed light-transmitting window 20 is installed at a suitable position on the left side of the vehicle. A camera 41 and an exterior lighting 42 are also installed on the upper left side of the vehicle. The lower part is a skirt door. The skirt is equipped with supporting legs 75, original vehicle batteries, power distribution control cabinet 33, power cable drum, supporting legs 75 and sewage tanks. Figure 4 shown.

[0042] The top of the vehicle is the control area of ​​the vehicle's purified airflow. A reasonable layout is adopted to ensure the ventilation, purification, one-way airflow and temperature and humidity control of the system. The main air duct 77, branch air duct 76, air supply power module 56, exhaust module 78, purified air supply port 46 and purified air exhaust port 35 are arranged on the roof. Fig.10 shown.

[0043] The front part of the vehicle is composed of the front part 14 and the front part of the vehicle body. In order to improve the overall appearance and driving reliability, a deflector is installed on the top of the front part 14. The front part of the vehicle body is equipped with a clearance lamp according to the regulations on vehicle road driving. The rear part of the vehicle is an air conditioner and generator maintenance door with a louvered window. The rear part of the vehicle is also equipped with a climbing ladder 54, a rear-view camera 41, a site lamp and a rear clearance lamp. Figure 8 shown.

[0044] like Figure 6 As shown, the AA section inside the vehicle is the partition area between the reagent preparation area 1 and the sample preparation area 2. This side is the reagent preparation area 1, the middle is the water tank 37, and the left side is the refrigerator 22 for placing reagents. The partition is equipped with a glass light-transmitting window 20, a transfer window 18 and a storage cabinet 57, and there is a mobile ultraviolet lamp 34 in front of the partition.

[0045] like Figure 7 As shown, the section BB in the vehicle is the partition area between the sample preparation area 2 and the amplification analysis area 3. This side is the sample preparation area 2. The two sides are equipped with a laboratory table 48, an oven 25 and a nucleic acid extractor 23. The middle is equipped with a biological safety cabinet 26. In order to ensure the installation stability of the safety cabinet, a ventilated safety cabinet installation support frame is set. Fig. 9 shown.

[0046] like Figure 8 As shown, the C1-C1 section in the vehicle is the partition area between the amplification analysis area 3 and the sample preparation area 2. This side is the amplification analysis area 3 and the sterilization area 7. The left part is the sterilization area 7, which is equipped with a transfer window 18 and a sterilizer. The waste from the sample preparation area 2 is transferred from this transfer window 18 to the sterilization area 7. The right part is the amplification analysis area 3, the right part is the first side pull-out box 13, and the side pull-out box is equipped with a laboratory table 48 and a computer 28. The right middle part is the pool 37, the light-transmitting window 20 and the transfer window 18. The product of the sample preparation area 2 is transferred from this transfer window 18 to the amplification analysis area 3. Fig. 9As shown, the C2-C2 section inside the vehicle is the area where the amplification analysis area 3 faces the vehicle front 14.

[0047] The laboratory provided in this application is designed strictly in accordance with the requirements of enhanced medical BSLG-2 biological laboratories, with highly integrated water, electricity, wind, detection equipment and other systems; the box is equipped with lighting, ultraviolet lamps, biological safety cabinets 26, instruments and equipment, refrigerators 22, etc.; the air supply duct is integrated and has a variable frequency power distribution function, and a separate exhaust fan is set; the drainage device uses a collection device, and the sewage tank needs to reserve a feeding port to pre-treat the sewage before discharge. Transportation to the site only requires a flat site and the necessary water and electricity connection to complete the installation. Each partition room has an independent lighting switch, and the ultraviolet lamp is equipped with a delay switch.

[0048] Glass windows are installed between each area, and glass windows are installed on the buffer door to facilitate communication and mutual observation. "Work Reminder" signs are installed at the entrance of each area to indicate the working or non-working status at that time; each room is equipped with a wash basin and hand washer 59.

[0049] In the interlocking state, the inner and outer doors of each buffer room in the car are interlocked and cannot be opened at the same time. There is an interlocking device to release the interlocking state. There is an intercom system between the external door and the interior, which can be used for intercom with the inside of the car.

[0050] The cab is equipped with vehicle navigation, rear view and driving recorder. The laboratory is a closed environment. An intercom device is used for experiments. In addition to talking to each other, the experimenters can also talk to the cab. The voice communication is carried out using the intercom system.

[0051] High-definition wide-angle cameras 41 are installed around the outside of the vehicle, high-definition cameras 41 are installed in various areas inside the vehicle, and a display is installed in the reagent preparation room. The display can display one or more camera 41 images as needed. The system has a storage function, and the image can be displayed and controlled through the remote display function via a mobile phone APP in a 5G transmission manner. It has an information transmission platform and a vehicle monitoring platform based on a 5G communication system, which can perform remote data transmission and match the corresponding hardware system to meet various emergency medical biological detection services.

[0052] The vehicle is equipped with mains power, power generation, UPS and charging inverter power supply systems, which can ensure the normal operation of various detection, air conditioning, purification, HVAC and auxiliary equipment in the vehicle, and enhance the endurance of the nucleic acid testing vehicle. The power supply system is controlled by the distribution board. The mains power supply uses an external cable reel, which is an electric and manual power cable reel; the power supply connector is waterproof ≥ level 6 standard; power generation, UPS and inverter are on-board self-contained power supply equipment, and the power distribution and power switching of the whole vehicle are realized through the distribution box. At the same time, it provides the whole vehicle with a cold area heating energy support system.

[0053] A purification air conditioner for parking is installed at the rear to ensure its use when connected to the mains and power generation. The cleanliness, temperature, humidity, ventilation frequency, pressure difference with the outdoors, noise, illumination and other parameters of each functional area inside the biosafety laboratory are guaranteed by the air supply and purification air conditioning system, purification supply and exhaust system and enclosed compartment. The requirements for various parameters are shown in the table below.

[0054]

[0055] The air conditioning, purification unit, air supply unit and other systems are operated with one button and have a high degree of intelligence. The automatic control system display screen and LCD touch control screen are installed inside, which can monitor the indoor temperature, humidity and pressure difference of the laboratory in real time. The temperature and humidity are displayed on the screen. If overpressure or underpressure occurs, it will automatically alarm. The control and system are integrated, and the full frequency conversion control is used to ensure that each cabin reaches the corresponding ventilation times and pressure gradient.

[0056] The experimental table top is a physical and chemical table top or a stainless steel plate, which is smooth, impermeable, erosion-resistant, heat-resistant and easy to clean. The experimental cabinet is made of high-quality impermeable steel plate, which is corrosion-resistant and tough. The cabinet door is double-layered with stainless steel, and the interior can be filled with sound insulation materials. The hinge adopts brand damping hinge anti-corrosion alloy material. The drawer adopts a buffer rail and can stay in any position at will.

[0057] All the vertical panels and ceilings of the laboratory are made of aluminum plates at the base layer, and the outer layer is made of acid- and alkali-resistant plates at the outer surface. The internal and external corners are made of oxidized aluminum alloy and sealed with acid- and corrosion-resistant sealants. The interior surface is sprayed with special nano-antibacterial coatings. The floor is Armstrong's special laboratory floor, which has anti-static, antibacterial and easy-to-clean properties.

[0058] The smart interconnection system uses network communication technology, automatic control technology and other intelligent technologies to effectively integrate various sensor devices and vehicle chassis information in special vehicles, realize centralized viewing and intelligent control of the status of all electrical and electronic equipment in the vehicle, and grasp the operating status of vehicle-installed equipment, environmental monitoring, power supply voltage and current, vehicle real-time positioning and other information at any time. It allows users to achieve real-time and comprehensive control of front-end vehicles at the remote end, effectively improving vehicle management efficiency and user experience.

[0059] The extended body of the present application is a side-pull compartment, which is distributed on both sides of the compartment and nested in the compartment. In combination with the functional requirements, the reagent preparation area 1 and the amplification analysis area 3 are each provided with a single-sided side-pull compartment on the left side of the vehicle, and the sample preparation area adopts a double-side pull form. The equipment and the work bench 48 are arranged in the side-pull compartment. After the side-pull compartment is unfolded, the working space is increased, which is convenient for personnel operation and activities. In the sample preparation room, the biological installation cabinet is placed in the middle solid cabin, which ensures its good ventilation and meets the requirements of the space height.

[0060] The present invention mainly solves the expansion and sealing problems of biological laboratories under mobile conditions, that is, when in driving state, the equipment can be folded to meet the requirements of vehicle road driving, and when in working state, the equipment can be unfolded to provide sufficient experimental area. At the same time, after expansion, the sealing requirements are met, thereby meeting the requirements of biosafety laboratories.

[0061] The laboratory was reasonably arranged under vehicle-mounted conditions to meet the requirements of purification, airflow and pressure difference, that is, the front of the purification air conditioner is the reagent preparation room, the sample preparation room and the amplification analysis room, which are arranged in sequence from the clean area, the polluted area to the highly polluted area. At the same time, the air conditioner, the air duct, the air pipe, the power supply and exhaust module 78 and the purification supply and exhaust outlet are reasonably arranged. The air supply is primary, medium and high-efficiency purification. The primary and medium-efficiency purification filters are installed in the front of the air conditioner, and the high-efficiency purification filter is at the end of the air duct after the air conditioner supplies air; the exhaust outlet is high-efficiency purification, and the wind pressure is automatically controlled to ensure the pressure difference ladder, one-way airflow and purification, such as Fig.10 shown.

[0062] According to the requirements of the biological laboratory, the layout fully considers the safety of personnel flow and item delivery to avoid cross contamination. In view of the limitation of vehicle space, personnel adopt an independent working mode, that is, personnel in each area enter their own room and work in an independent space without affecting each other. Information transmission is completed through intercom, and item delivery is completed through the delivery window. The setting of the item delivery path ensures one-way delivery, meets the principle of no return and no cross, and controls vehicle flow and logistics.

[0063] The system uses 5G communication technology to upload monitoring data to the cloud, cope with the challenges of massive storage, backup and computing power requirements of vehicle data, and solve a large number of engineering problems. It enables users to remotely view vehicle equipment operating status, vehicle real-time positioning, vehicle real-time power supply voltage, video monitoring, electronic fences and other information anytime and anywhere through the cloud platform and APP, achieving effective real-time dynamic monitoring and management of vehicles.

[0064] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An expandable mobile biosafety laboratory, comprising a vehicle head (14), a chassis and a carriage, wherein the chassis is located at the rear of the vehicle head (14), and the carriage is mounted on the chassis, characterized in that: The carriage is provided with an amplification analysis area (3), a sample preparation area (2) and a reagent preparation area (1) in sequence from the front (14) to the rear; the amplification analysis area (3), the sample preparation area (2) and the reagent preparation area (1) are separated by a sealed partition; one side of the carriage is provided with a first side drawer (13), a second side drawer (12) and a third side drawer (11) in sequence from the front (14) to the rear; the first side drawer (13) is located in the amplification analysis area (3), the second side drawer (12) is located in the sample preparation area (2), and the third side drawer (11) is located in the reagent preparation area (1); the first side drawer (13), the second side drawer (12) and the third side drawer (11) are all arranged to slide and be pulled with the carriage; The sample preparation area (2) is provided with a fourth side drawer (10) on a side opposite to the second side drawer (12), and the reagent preparation area (1) is provided with a side drawer platform (15) on a side opposite to the third side drawer (11); the amplification analysis area (3), the sample preparation area (2) and the reagent preparation area (1) are respectively provided with a first door (16), a second door (27) and a third door (29); a biological safety cabinet (26) is installed in the middle of the sample preparation area (2); A first boarding ladder (19) is provided on the side of the amplification analysis area (3) opposite to the first side pull compartment (13); a second boarding ladder (38) is provided on the side pull platform (15), and the second boarding ladder (38) is slidably connected to the side pull platform (15); The amplification analysis area (3), the sample preparation area (2) and the reagent preparation area (1) are respectively provided with an amplification buffer area (6), a sample buffer area (5) and a reagent buffer area (4); A sterilization zone (7) is provided on one side of the amplification analysis zone (3) close to the sample preparation zone (2), and the sterilization zone (7) is in communication with the amplification buffer zone (6); The second side pull box (12) is provided with an equipment door (40); The amplification analysis area (3), the sample preparation area (2) and the reagent preparation area (1) are all provided with a water pool (37), and the sample buffer area (5) and the reagent buffer area (4) are both provided with a hand washer (59); Transfer windows (18) are provided between the reagent preparation area (1) and the sample preparation area (2), between the sample preparation area (2) and the amplification analysis area (3), between the amplification analysis area (3) and the sterilization area (7), and between the sterilization area (7) and the sample preparation area (2). A transfer window (18) is also provided on the wall of the fourth side drawer (10).

2. The expandable mobile biosafety laboratory according to claim 1, characterized in that: An air conditioner outdoor unit (30) and a purification air conditioner main unit (31) are provided on the side of the reagent preparation area (1) away from the sample preparation area (2); a main air duct (77) is provided on the top of the laboratory, and the main air duct (77) is connected to the purification air conditioner main unit (31); the amplification analysis area (3), the sample preparation area (2), the reagent preparation area (1), the amplification buffer area (6), the sample buffer area (5), the reagent buffer area (4) and the sterilization and disinfection area (7) are all provided with purification air supply outlets (46), and each of the purification air supply outlets (46) is connected to the main air duct (77) through a branch air duct (76); each of the branch air ducts (76) is connected to an air supply power module (56); and exhaust modules (78) are installed in the amplification buffer area (6), the sample buffer area (5) and the reagent buffer area (4).

3. The expandable mobile biosafety laboratory according to claim 1, characterized in that: Support legs (75) are provided under the chassis.

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