Thromboelastometer

Abstract

The present invention discloses a thromboelastometry instrument, which includes a support, a cup body, a cup cover, a detection body, a first magnetic ball, and a second magnetic ball. The detection body is swingably connected to the support hanging column around a horizontal axis. The bottom of the detection body loaded with the cup cover is rod-shaped and its bottom is inserted into the cup body. The detection body and the cup body wall and the bottom of the cup body are spaced apart. After the blood to be tested in the cup body coagulates, the coagulated blood driven by the movement of the cup body will drive the detection body to swing, and the physical properties of the blood can be judged by detecting the amplitude and angle of the swing. In order to allow the detection body to swing with the coagulated blood, the present invention swingably connects the detection body and the support hanging column through two magnetic balls. The two magnetic balls include a first magnetic ball and a second magnetic ball. The first magnetic ball is fixedly connected to the support hanging column, and the top of the second magnetic ball is connected to the first magnetic ball by magnetic attraction, and the bottom of the second magnetic ball is fixedly connected to the detection body. During the rotation of the detection body, the second magnetic ball is driven to deflect.

Description

Technical Field

[0001] The present invention relates to the technical field of medical detection equipment, and in particular to a thrombus elastometer. Background Art

[0002] After human blood is extracted from the human body, the coagulation factors in the blood will produce a series of changes in state, such as coagulation and fibrinolysis. Through clinical monitoring, there are significant differences in the state of normal blood and pathological blood during the coagulation process. This difference is mainly reflected in the rate of coagulation and fibrinolysis and the strength of coagulation. This difference in rate and strength can provide objective guidance for the clinical diagnosis of cardiovascular and cerebrovascular diseases. The detection principle of the thromboelastometry is to detect and analyze the physical properties (rate, strength) of human blood. Different from other coagulation detection and analysis equipment that only detects the time segment of the coagulation process, the thromboelastometry can reflect the whole picture of human coagulation, that is, the entire coagulation and fibrinolysis process.

[0003] The principle of the thromboelastometry in the prior art is as follows: blood is placed in a cup, the bottom of the cup cover has a column, and the column cover is provided with an elastic member, which provides a micro-resistance to the cup cover to offset the thrust of the column in the blood, the column is inserted into the blood in the cup, and then the cup is rotated. During the blood coagulation and thrombolysis process, the column is driven by the blood and deflected, and the physical properties of the blood can be judged by the deflection angle and the blood coagulation time. In addition, a coil is provided on the cup, and the coil generates a magnetic field during the movement of the column. The prior art uses a Hall sensor to detect the angle of column deflection.

[0004] The thromboelastometry in the prior art has the following problems: 1. The elastic wire will fatigue and wear during long-term use, thus affecting the accuracy of the test. 2. The thromboelastometry in the prior art is susceptible to interference from external electromagnetic fields. In order to shield external interference, the detection mechanism needs to be placed in a shielding device, which increases the complexity. 3. The thromboelastometry in the prior art will vibrate during the swinging of the cup body, thereby affecting the swing amplitude of the column, and the cup body will also be affected by environmental vibrations during the swinging process, and the prior art does not have any anti-vibration measures. Summary of the invention

[0005] The purpose of the present invention is to provide a thrombus elastometer to solve the problems existing in the above-mentioned prior art. In order to solve the above-mentioned problems, according to one aspect of the present invention, a thrombus elastometer is provided.

[0006] include:

[0007] Bracket,

[0008] A cup body, the cup body is swingably connected to the bracket around a vertical axis; the cup body is used to contain a test liquid sample;

[0009] A detection body, located above the cup body and spaced apart from the cup body;

[0010] A cup cover, the cup cover is detachably connected to the bottom of the detection body, the bottom of the cup cover is provided with a detection column, the detection column is located in the cup body and is spaced apart from the inner wall of the cup body;

[0011] A first magnetic ball, the first magnetic ball is fixedly connected to the bottom of the bracket; and

[0012] A second magnetic ball, the top of which is connected to the first magnetic ball by magnetic attraction and the bottom of which is fixedly connected to the top of the detection body;

[0013] The micro resistance generated by the first magnetic ball when the second magnetic ball is driven away from the axis during the swinging of the detection body can suppress the resistance generated by the second magnetic ball during the movement of the second magnetic ball in the liquid.

[0014] In one embodiment, a cup holder is further included, wherein the cup holder has a receiving cavity, wherein a top opening of the receiving cavity is used for detachably receiving the cup body, and the cup holder is swingably connected to the bracket.

[0015] In one embodiment, it further comprises a rotating arm, the top of which is swingably connected to the bracket, and a sensor is provided on the rotating arm, and the sensor is used to sense the swing angle of the rotating arm;

[0016] The cup holder is detachably connected to the bottom of the rotating arm.

[0017] In one embodiment, the cup holder is detachably connected to the rotating arm by magnetic attraction.

[0018] In one embodiment, the cup body has a rectangular cross section along the horizontal direction, and includes a first portion and a second portion along the vertical direction. The second portion has a semicircular cross section along the vertical direction, and the first portion extends upward from the top of the second portion.

[0019] In one embodiment, a cavity is provided at the bottom of the cup holder, and the cavity is connected to the accommodating cavity;

[0020] The thromboelastometry instrument further includes a temperature control module, which is located below the cup seat and includes:

[0021] A heating component, the heating component is configured to be operably moved into the cavity and spaced apart from the cup body;

[0022] A temperature control device is connected to the heating component by a signal and is used to sense and control the heating component.

[0023] In one embodiment, the detection body is a column, the top of the cup cover has a concave cavity, the concave cavity extends in a vertical direction, and the bottom of the detection body can be inserted into the concave cavity.

[0024] In one embodiment, the detection body is further provided with a marking symbol, and the marking symbol extends along its circumference;

[0025] The thrombus elastometer also includes a camera, which is connected to the bracket and arranged opposite to the marking symbol and is configured to capture the movement trajectory of the marking symbol, and the shooting angle of the camera is a horizontal viewing angle.

[0026] In one embodiment, a hanging column is provided on the top of the first magnetic ball, and the hanging column is movably connected to the bracket.

[0027] In one embodiment, the diameter of the first magnetic ball ranges from 2.5 mm to 4 mm, and the diameter of the second magnetic ball ranges from 7 mm to 9 mm.

[0028] In one embodiment, the radius of the second portion ranges from 8 mm to 10 mm, and the height of the first portion along the vertical direction ranges from 3 mm to 5 mm.

[0029] In one embodiment, a limit baffle is also included, which is connected to the bracket and extends in the horizontal direction. The limit baffle can move in the vertical direction. The limit baffle is also provided with a through hole, and the through hole can allow the bracket hanging column, the first magnetic ball and the second magnetic ball to pass through, and can block the detection object from passing through.

[0030] In one embodiment, the first magnetic ball and the second magnetic ball are both permanent magnetic Bucky magnetic balls.

[0031] The present invention realizes micro-resistance to the detection object in the direction of gravity at 360 degrees through two magnetic balls. The micro-resistance increases with the increase of the swing angle, which can not only resist external interference factors, but also improve the life of the thromboelastometry instrument by the spring-free permanent magnetic ball adsorption design. In addition, the rotating arm of the present invention is provided with a sensor for sensing the swing amplitude of the rotating arm, and the rotating arm can be controlled to reset after the test. In addition, the heating component of the present invention does not contact the cup body, and can evenly heat the cup body to simulate the human body environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 FIG. 1 is a schematic diagram of a thrombus elastometer according to an embodiment of the present invention.

[0033] Figure 2 yes Figure 1 Top view of the cup holder of the illustrated embodiment.

[0034] Figure 3 yes Figure 1Right side view of the cup holder of the illustrated embodiment.

[0035] Figure 4 yes Figure 1 Left side view of the cup body of the illustrated embodiment.

[0036] Figure 5 yes Figure 1 Top view of the cup body of the illustrated embodiment.

[0037] Figure 6 yes Figure 1 Schematic diagram of a test body according to the illustrated embodiment.

[0038] Figure 7 yes Figure 1 Schematic diagram of the cup cover of the illustrated embodiment.

[0039] Figure 8-Figure 10 It is a schematic diagram of a camera and a detection object according to an embodiment of the present invention.

[0040] Fig.11 and Fig.12 It is a schematic diagram of magnetic suspension of a thrombus elasticity meter detection body according to an embodiment of the present invention.

[0041] Fig.13 and Fig.14 It is a schematic diagram of the first magnetic ball and the second magnetic ball of the present invention.

[0042] Fig.15 FIG. 4 is a hardware schematic diagram of a single-channel system according to an embodiment of the present invention.

[0043] Figure numerals: 100, thrombus elastic meter; 1, bracket; 11, hanging column; 2, cup body; 21, first part; 22, second part; 23, card strip; 3, detection body; 31, marking symbol; 32, cup cover; 33, detection column; 4, first magnetic ball; 5, second magnetic ball; 6, cup holder; 61, accommodating cavity; 62, card slot; 63, connecting end; 7, rotating arm; 8, limit baffle; 9 camera; 91, fill light. DETAILED DESCRIPTION

[0044] The preferred embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings so that the purpose, features and advantages of the present invention can be more clearly understood. It should be understood that the embodiments shown in the accompanying drawings are not intended to limit the scope of the present invention, but are only intended to illustrate the essential spirit of the technical solution of the present invention.

[0045] In the following description, certain specific details are set forth for the purpose of illustrating the various disclosed embodiments to provide a thorough understanding of the various disclosed embodiments. However, those skilled in the relevant art will recognize that the embodiments may be practiced without one or more of these specific details. In other cases, well-known devices, structures, and techniques associated with the present application may not be shown or described in detail to avoid unnecessarily obscuring the description of the embodiments.

[0046] References throughout the specification to "one embodiment" or "an embodiment" indicate that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of "in one embodiment" or "in an embodiment" in various places throughout the specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any manner in one or more embodiments.

[0047] In the following description, in order to clearly show the structure and working mode of the present invention, many directional words will be used for description, but the words "front", "back", "left", "right", "outside", "inside", "outward", "inward", "up", "down", etc. should be understood as convenient terms and should not be understood as restrictive terms.

[0048] The present invention relates to a thrombus elastometer 100, such as Figure 1As shown, the thromboelastometry instrument 100 includes a bracket 1, a cup body 2, a cup cover 32, a detection body 3, a first magnetic ball 4 and a second magnetic ball 5, wherein the bracket 1 is used to support the detection body 3 and the cup body 2, the cup body 2 is used to place the liquid sample to be detected, and the cup body 2 is swingably connected to the bracket 1 around a vertical axis. The first magnetic ball 4 and the second magnetic ball 5 facilitate the swingable connection of the detection body 3 to the bracket 1. Specifically, the detection body 3 is located above the cup body 2 and is spaced apart from the cup body 2, the cup cover 32 is detachably connected to the bottom of the detection body 3, and a detection column 32 is provided at the bottom of the cup cover 32, and the detection column is located in the cup body 2 and is spaced apart from the inner wall of the cup body. In practice, after the blood to be detected in the cup body 2 coagulates, the coagulated blood will drive the detection column 32 to swing with the cup body 2, and the detection column 32 drives the detection body 3 to swing, and the physical properties of the blood can be judged by detecting the swing amplitude and the swing angle of the detection body 3. In order to make the detection body 3 swing with the coagulated blood, the present invention connects the detection body 3 and the bracket 1 swingably through two magnetic balls. The two magnetic balls include a first magnetic ball 4 and a second magnetic ball 5. The first magnetic ball 4 is connected to the bracket 1, and the top of the second magnetic ball 5 is connected to the first magnetic ball 4 by magnetic attraction, and the bottom of the second magnetic ball 5 is connected to the detection body 3. During the rotation of the detection body 3, the second magnetic ball 5 can be driven to deflect. Moreover, the micro-resistance generated by the first magnetic ball 4 when the second magnetic ball 5 is driven to deviate from the axis during the swinging process of the detection body 3 can suppress the resistance generated by the second magnetic ball 5 during the movement of the liquid. As the blood gradually coagulates, the detection body 3 is driven by the gradually coagulated blood to gradually deviate from the axis of the first magnetic ball 4 in the vertical direction. The physical properties of the blood to be tested can be judged by the amplitude and time of the deviation of the detection body 3 from the axis of the first magnetic ball 4 in the vertical direction. When the blood is not coagulated, the blood in the cup body 2 will flow during the rotation of the cup body 2, and the flowing blood will also exert a certain impact force on the detection body 3. The suction force between the first magnetic ball 4 and the second magnetic ball 5 can suppress the impact force, that is, when the blood is not coagulated, the detection body 3 is inserted into the cup body 2 in the vertical direction. During the swinging of the cup body 2, the blood flowing in the cup body 2 will not drive the detection body 3 to swing. Only during the coagulation of the blood will the coagulated blood drive the detection plate to deviate from the axis of the first magnetic ball 4 in the vertical direction. The present invention allows the detection body 3 to swing along the bracket 1 through the cooperation of the first magnetic ball 4 and the second magnetic ball 5, and the suction force between the first magnetic ball 4 and the second magnetic ball 5 can suppress the impact force of the liquid on the detection body 3, so that the detection body 3 maintains a vertical direction in the uncoagulated blood, and the state of the test can be observed conveniently. Moreover, the suction force of the first magnetic ball 4 and the second magnetic ball 5 will not have the phenomenon of spring being worn and aged or losing elasticity in the prior art, so as to ensure the accuracy of the thrombus elasticity test. In addition, if the second magnetic ball 5 is deflected in a non-test direction due to external interference vibration, the micro resistance between the first magnetic ball 4 and the second magnetic ball 5 will inhibit the deflection of the second magnetic ball 5 .

[0049] In addition, the thrombus elastometer 100 further includes a cup seat 6, and the cup seat 6 can be swingably connected to the bracket 1. Figure 2 and Figure 3 As shown, the cup holder 6 has a receiving cavity 61, and the top of the receiving cavity 61 is open for detachably receiving the cup body 2. The cup body 2 and the cup cover 32 are generally disposable consumables, and the cup body 2 can be installed in the receiving cavity 61 of the cup holder 6 and driven by the cup holder 6. Figure 2 and Figure 4 In the embodiment shown, the side wall of the accommodating cavity 61 is provided with a card slot 62, and the card slot 62 extends from the top of the accommodating cavity 61 to the bottom of the accommodating cavity 61, and the side wall of the cup body 2 is also provided with a card strip 23 that matches the card slot 62, and the card strip 23 extends from the top of the side wall of the cup body 2 to the bottom, and the cup body 2 is installed in the accommodating cavity 61 from top to bottom, and the card strip 23 can be inserted into the card slot 62, so that the cup body 2 is fixed in the accommodating cavity 61. It should be understood that the card-detachable connection method of the cup body 2 and the cup holder 6 is not limited to the above-mentioned embodiment, and those skilled in the art can also use other detachable methods as needed.

[0050] Optionally, the thromboelastometry instrument 100 further includes a rotating arm 7 and a motor rotating shaft, and further reference is made to Figure 1 The motor shaft is connected to the bracket, and the top of the rotating arm 7 is swingably connected to the motor shaft. In addition, a sensor is provided on the rotating arm 7, and the sensor is used to sense the swing angle of the rotating arm 7. After the test is completed, the rotating arm can also be controlled to rotate to a vertical state, so that the cup holder 6 can be taken and placed conveniently.

[0051] Furthermore, the cup holder 6 is detachably connected to the rotating arm 7 by magnetic attraction. Preferably, a permanent magnet can be provided on the cup holder 6, and a coil can be provided on the rotating arm 7. By energizing or de-energizing the coil, the cup holder 6 and the rotating arm 7 can be detachably connected. Moreover, when the cup holder 6 needs to be taken out of the rotating arm 7, the coil can be directly de-energized, and the attraction between the cup holder 6 and the rotating arm 7 can disappear immediately, thereby avoiding the phenomenon of friction and shaking of the cup holder 6 during the separation from the rotating arm 7. Furthermore, in Figure 2 and Figure 3 In the embodiment, the cup holder 6 is provided with a connecting end 63 on a side away from the accommodating cavity 61, and a accommodating groove is provided at the bottom of the rotating arm 7, which can accommodate the connecting end 63, and the magnetic iron sheet is fixed on the connecting end 63, and the electromagnet or electromagnetic coil can be set in the accommodating groove of the rotating arm 7, and the cup holder 6 is connected to the rotating arm 7 by magnetic attraction, which is convenient for installation, and will not cause the cup holder 6 and the rotating arm 7 to wear during the long-term disassembly process, and can increase the service life of the cup holder 6 and the rotating arm 7. Of course, those skilled in the art can also connect the cup holder 6 and the rotating arm 7 by magnetic attraction in other ways. In addition, the rotating arm 7 can be connected to the rotating shaft of the motor through an adapter, and the rotating arm 7 and the cup holder 6 are driven to swing by the motor.

[0052] Preferably, if Figure 4 and Figure 5 As shown, the cup body 2 has a rectangular cross section along the horizontal direction, and includes a first portion 21 and a second portion 22 along the vertical direction. The second portion has a semicircular cross section along the vertical direction, and the first portion extends upward from the top of the second portion. Figure 4 and Figure 5 As shown, pouring a small amount of blood into the second portion 22 of the semicircular cross-section can provide a sufficient height, thereby reducing the amount of sample collected.

[0053] Optionally, since the blood test needs to simulate the human body environment, a temperature control module can also be provided for the cup holder 6. The temperature control module is located below the cup holder 6, and a cavity is also provided below the cup holder 6. The cavity is connected to the accommodating cavity 61. The temperature control module can heat the cup body 2 through the cavity and control the temperature of the cup body 2. The temperature control module includes a heating component, a lifting device and a temperature control device, wherein the heating component is connected to the upgrading device. When testing is required, the heating component is driven by the upgrading device to be lifted into the cavity of the cup holder 6, and the heating component and the cup body 2 are arranged at intervals, that is, the cup body 2 is heated in a non-contact manner. During the test, the cup holder 6 will not contact the heating component when rotating, realizing non-contact heating in motion mode. The temperature control device is signal-connected or electrically connected to the heating component for sensing and controlling the heating component. Preferably, the heating component is a ceramic heating plate, and the ceramic heating plate is vertically mounted on the upgrading device and is located below the cup holder 6. Before the test, the lifting device lifts the ceramic heating plate and places it in the cavity. The cavity is preferably spaced and relatively arranged with the two semicircular side walls in the second part of the cup body 2. After the ceramic heating plate is lifted into the cavity, it will heat the side of the cup body 2, which can increase the heating area. Preferably, the temperature control device adopts an infrared temperature measurement module, and uses the bottom of the cup body 2 as the detection target to achieve contactless temperature control. It should be understood that the cavity can also be set at other positions of the cup holder, as long as the heating component and the temperature control device can function.

[0054] Optionally, the detection body 3 is a cylinder, and the detection body 3 includes a first section and a second section, wherein the first section is connected to the top of the second section, and the diameter of the first section is larger than that of the second section, and the second magnetic ball 5 is located at the top of the first section. A concave cavity is provided at the top of the cup cover 32, and the concave cavity can accommodate the second section of the detection body 3, so that the cup cover 32 can be detachably connected to the bottom of the detection body 3. It should be understood that the cup cover 32 can also be detachably connected to the detection body 3 in other ways, and the connection method of the cup cover 32 and the detection body is not limited.

[0055] Furthermore, a marking symbol 31 is also provided on the first section. The marking symbol 31 is located on the first section and extends along the circumference of the first section. The marking symbol 31 is used to determine the deflection angle of the detection body 3. In addition, a camera module can be configured on the bracket 1. The camera module includes a camera, which can enable the camera and the marking symbol 31 to be arranged relative to each other, and can capture the movement trajectory of the marking symbol 31. It should be understood that the marking symbol 31 is a uniform annular line, so when the detection body 3 is suspended to the first magnetic ball 5 on the bracket 1 through the first magnetic ball 4, no specific alignment is required, thereby achieving the convenience of free alignment. In addition, the shooting angle of the camera 9 is a horizontal angle of view. The normal shooting angle of the camera 9 is a vertical angle of view, that is, the captured image is consistent with the real object, and Figure 8 , Fig. 9 and Fig.10 In the shown embodiment, the camera 9 is adjusted to a horizontal viewing angle, that is, the camera 9 is rotated 90° for shooting. The camera 9 is located on one side of the swinging direction of the test object 3. During the shooting process, the marking symbol 31 opposite to the camera 9 swings along with the test object 3. The camera 9 is adjusted to a horizontal viewing angle, and the motion trajectory of the marking symbol 31 captured can be a trace. The real-time position detection of the trace can be used to identify the swinging angle of the test object 3 and the physical properties of the blood. The trace position is captured by a horizontal viewing angle on a line of data output by the line-by-line output camera, which is conducive to rapid acquisition and processing of data.

[0056] Optionally, a suspension column 11 is provided on the top of the first magnetic ball 4, and the suspension column 11 is movably connected to the bracket 1, and the suspension column can drive the first magnetic ball 4 to move up and down. Figure 1 , Fig.11 and Fig.12 In the illustrated embodiment, a wire handle is provided on the top of the hanging column 11, and the wire handle and the hanging column 11 can be driven by a motor to move in the vertical direction, and the second magnetic ball 5 and the detection body 3 will move with the first magnetic ball 4. Before the test, the first magnetic ball 4 is first moved upward, and after the cup cover 32 is connected, the second magnetic ball 5 is adsorbed to the first magnetic ball 4, and then the hanging column 11 is moved, and the first magnetic ball 4, the second magnetic ball 5 and the detection body 3 are moved accordingly, and then the detection column at the bottom of the cup cover 32 is inserted into the blood in the cup body 2. After the test, the first magnetic ball 4 is first moved upward for a certain distance, so that the detection body 3 is separated from the first magnetic ball 4, and then the cup seat 6 is removed from the rotating arm 7. Then the cup cover 32 is separated from the detection body 3 and the cup body 2 is separated from the cup seat 6, and the consumable cup cover 32 and the cup body 2 can be discarded as required.

[0057] Optionally, the diameter of the first magnetic ball 4 ranges from 2.5mm to 4mm, and the diameter of the second magnetic ball 5 ranges from 7mm to 9mm. The suction force and micro-resistance between the first magnetic ball 4 and the second magnetic ball 5 are controlled by the sizes of the first magnetic ball 4 and the second magnetic ball 5, so that the suction force of the first magnetic ball 4 and the second magnetic ball 5 can drive the second magnetic ball 5, the detection body 3 and the cup cover 32 to move up and down, and in the process of the second magnetic ball 5 swinging with the detection body 3, the micro-resistance between the first magnetic ball 4 and the second magnetic ball 5 that increases with the deflection angle can also make the deviation angle of the second magnetic ball 5 not exceed the detection angle range. In addition, when there are interference factors in the environment, causing the second magnetic ball 5 to deviate from the vertical axis of the first magnetic ball 4, the micro-resistance between the two also suppresses interference jitter. Preferably, as Fig.13 and Fig.14 As shown, the diameter of the first magnetic ball 4 is 3 mm, and the diameter of the second magnetic ball 5 is 8 mm.

[0058] Optionally, the radius of the second portion 22 ranges from 8mm to 10mm, and the height of the first portion 21 along the vertical direction ranges from 3mm to 5mm, that is, the depth of the entire cup body 2 ranges from 11mm to 15mm. Figure 4 In the embodiment shown, the radius of the second portion 22 is 9 mm, the height of the first portion 21 in the vertical direction is 3 mm, and the depth of the entire cup body 2 is 13 mm. In addition, in the embodiment of the figure, the inner diameter of the first portion 21 in the horizontal direction is 16 mm, which can ensure that the cup body 2 will not touch the detection body 3 during the swinging process.

[0059] Optionally, the bracket 1 is further provided with a limit baffle 8 which can move in the vertical direction, and further reference is made to Fig.11 and Fig.12 The limit baffle 8 is placed horizontally and is provided with a through hole, which allows the first magnetic ball 4, the hanging column 11 and the second magnetic ball 5 to pass through, but blocks the detection body 3 from passing through, that is, the size of the through hole is smaller than the size of the detection body, which can help remove the detection body 3 from the first magnetic ball 4. Specifically, after the test, the first magnetic ball 4 and the second magnetic ball 5 are driven to move upward through the through hole of the limit baffle 8, while the detection body 3 is blocked by the limit baffle 8, so that the detection body 3 and the second magnetic ball 5 can be separated from the first magnetic ball 4. After separation, the detection body 3 falls on the cup body 2, and then the cup seat 6 is removed from the rotating arm 7, and then the cup cover 32 is detached from the detection body 3 and the cup body 2 is detached from the cup seat 6. The consumable cup cover 32 and the cup body 2 can be discarded as required, and finally the limit baffle 8 is reset upward for a distance to prepare for the next test. The limit baffle 8 can be driven by a lead screw motor to move in the vertical direction, and is located above the second magnetic ball 5 during testing to avoid limiting the swing of the detection body 3 .

[0060] Optionally, the first magnetic ball 4 and the second magnetic ball 5 are both permanent magnetic Bucky magnetic balls. Fig.13 and Fig.14 The first magnetic ball 4 and the second magnetic ball 5 have positive and negative poles on both sides along the vertical direction. The first magnetic ball 4 and the second magnetic ball 5 are attracted to each other on one side. Once the second magnetic ball 5 deviates from the axis of the first magnetic ball 4 along the vertical direction, it will be subject to the repulsive force on the other side of the first magnetic ball 4, that is, the micro-resistance generated by the first magnetic ball 4 on the second magnetic ball 5. In the absence of thrust, the second magnetic ball 5 can be reset.

[0061] In addition, the thrombus detector of the present invention is a single-channel detector, that is, only one cup body 2 is installed on each cup holder 6, while in other embodiments, multiple accommodating cavities 61 can also be provided on the cup holder 6 to accommodate multiple cup bodies 2, thereby forming a multi-channel detection.

[0062] Furthermore, the thromboelastometry instrument 100 of the present invention further comprises a plurality of interface modules, which are used to control the motor motion control of the rotating arm 7, the image capture of the camera 9, the contactless temperature control, the movement of the suspension column 11 and the limit baffle 8, etc., and the plurality of interface modules are also connected to the main control board, and the operation of the plurality of interface modules is controlled by the main control board. Fig.15 In the illustrated embodiment, the main control board is embedded.

[0063] In the hardware system of the present invention, a 220V to 12V AC to DC conversion adapter is used, and the system outputs 12V and 5V to each system through a power distribution board.

[0064] For the loading and unloading coordination of the cup holder 6 and the rotating arm 7, the circuit system is provided with an active buzzer and a button. When the button is pressed, after a preset time, the interface module is turned on, and the coil is powered on or off and a status reminder is given through the buzzer.

[0065] The thromboelastometry instrument 100 also includes a camera detection interface board, multiple fill-in lights 91 and a fill-in light 91 driver board. The fill-in lights 91 are installed near the camera 9. The embedded main control board and the camera detection interface communicate in full duplex, using the RS232 transmission method. The camera detection interface board is connected to the fill-in light driver interface board to control the on and off of the multiple fill-in lights 91, and configures the camera 9 and obtains image data through the I2C interface and DCMI interface of the MCU chip STM32H750VBT6.

[0066] The thromboelastometry instrument 100 also includes a rotating arm control interface board, a contactless temperature control interface board, an environmental vibration detection interface board, etc. The embedded main control board and the rotating arm control interface board, the contactless temperature control interface board, the environmental vibration detection interface board, and the camera detection interface board are all in a master-slave relationship. The embedded main control board can control the operation of the rotating arm control interface board, the contactless temperature control interface board, the environmental vibration detection interface board, and the camera detection interface board. In addition to the camera detection interface board, the present invention uses CAN communication with the main control board, and the camera detection interface board and the main control board use a UART to RS232 serial port mode, and the CAN interface implements a differential line daisy chain mode to simplify the control and connection scheme.

[0067] The rotating arm control interface board communicates with the sensor board through the UART interface of the MCU chip STM32F030C6T6, and can obtain the angle information of the rotating arm 7, and uses the chip ULN2003 as a motor drive component.

[0068] The contactless temperature control interface board controls the current on and off of the ceramic heater through the switch module, and the ceramic heater heats the cup body 2 through close air. The infrared temperature measurement module on the contactless temperature control interface board detects the temperature of the bottom of the cup body 2, and the MCU chip STM32F030F4P6 reads the temperature and controls the heating to achieve temperature control.

[0069] The environmental vibration detection interface board is connected to the sensor module, and the MCU chip STM32F103C8T6 obtains real-time inclination data through two ADC sampling, and then the embedded main control board reads the data and sends it to the human-computer interaction computer.

[0070] The embedded main control board is connected to the LCD display module through the IIC bus to display some simple process information in a fast and intuitive way. The embedded main control board is connected to Bluetooth through the UART bus, and realizes wireless serial port communication with the human-computer interaction computer through Bluetooth, and can receive instructions issued by the human-computer interaction computer or upload data.

[0071] The present invention realizes magnetic suspension and variable micro-resistance of the detection body 3 through two magnetic balls, which can not only resist external interference factors, but also improve the life of the thromboelastometry instrument 100. In addition, the rotating arm 7 of the present invention is provided with a sensor for sensing the swing amplitude of the rotating arm 7. After the test, the rotating arm 7 can be controlled to reset, which is convenient for taking and placing the cup holder 6 and reducing operational jitter. In addition, the heating component and temperature detection module of the present invention do not contact the cup body 2, realize non-contact temperature control, and can evenly heat the cup body 2 to simulate the human body environment.

[0072] The preferred embodiments of the present invention have been described in detail above, but it should be understood that after reading the above teachings of the present invention, those skilled in the art may make various changes or modifications to the present invention. These equivalent forms also fall within the scope defined by the appended claims of this application.

Claims

1. A thrombus elastometer, characterized in that: include: Bracket, A cup body, the cup body is swingably connected to the bracket around a vertical axis; the cup body is used to contain a test liquid sample; A detection body, located above the cup body and spaced apart from the cup body; A cup cover, the cup cover is detachably connected to the bottom of the detection body, the bottom of the cup cover is provided with a detection column, the detection column is located in the cup body and is spaced apart from the inner wall of the cup body; a first magnetic ball, the first magnetic ball being fixedly connected to the bottom of the bracket; as well as A second magnetic ball, the top of which is connected to the first magnetic ball by magnetic attraction and the bottom of which is fixedly connected to the top of the detection body; The micro resistance generated by the first magnetic ball when the second magnetic ball is driven away from the axis during the swinging of the detection body can suppress the resistance generated by the second magnetic ball during the movement of the second magnetic ball in the liquid.

2. The thrombus elastometer according to claim 1, characterized in that: It also includes a cup holder, which has a receiving cavity. The top opening of the receiving cavity is used to detachably receive the cup body. The cup holder can be swingably connected to the bracket.

3. The thrombus elastometer according to claim 2, characterized in that: It also includes a rotating arm, the top of which is swivellably connected to the bracket, and a sensor is provided on the rotating arm, and the sensor is used to sense the swing angle of the rotating arm; The cup holder is detachably connected to the bottom of the rotating arm.

4. The thrombus elastometer according to claim 3, characterized in that: The cup holder is detachably connected to the rotating arm by magnetic attraction.

5. The thrombus elastometer according to claim 2, characterized in that: The cup body has a rectangular cross section along the horizontal direction, and includes a first portion and a second portion along the vertical direction. The second portion has a semicircular cross section along the vertical direction, and the first portion extends upward from the top of the second portion.

6. The thrombus elastometer according to claim 2, characterized in that: A cavity is provided at the bottom of the cup holder, and the cavity is connected to the accommodating cavity; The thromboelastometry instrument further includes a temperature control module, which is located below the cup seat and includes: A heating component, the heating component is configured to be operably moved into the cavity and spaced apart from the cup body; A temperature control device is signal-connected to the heating component and is used to sense and control the heating component.

7. The thrombus elastometer according to claim 1, characterized in that: The detection body is a column, the top of the cup cover is provided with a concave cavity, the concave cavity extends in a vertical direction, and the bottom of the detection body can be inserted into the concave cavity.

8. The thrombus elastometer according to claim 7, characterized in that: The detection body is also provided with a marking symbol, and the marking symbol extends along its circumference; The thrombus elastometer also includes a camera, which is connected to the bracket and arranged opposite to the marking symbol and is configured to capture the movement trajectory of the marking symbol, and the shooting angle of the camera is a horizontal viewing angle.

9. The thrombus elastometer according to claim 1, characterized in that: A hanging column is provided on the top of the first magnetic ball, and the hanging column is movably connected to the bracket.

10. The thrombus elastometer according to claim 1, characterized in that: The diameter of the first magnetic ball ranges from 2.5 mm to 4 mm, and the diameter of the second magnetic ball ranges from 7 mm to 9 mm.

11. The thrombus elastometer according to claim 5, characterized in that: The radius of the second part ranges from 8mm to 10mm, and the height of the first part along the vertical direction ranges from 3mm to 5mm.

12. The thrombus elastometer according to claim 9, characterized in that: It also includes a limit baffle, which is connected to the bracket and extends in the horizontal direction. The limit baffle can move in the vertical direction. The limit baffle is also provided with a through hole, and the through hole can allow the bracket hanging column, the first magnetic ball and the second magnetic ball to pass through, and can block the detection object from passing through.

13. The thrombus elastometer according to claim 1, characterized in that: The first magnetic ball and the second magnetic ball are both permanent magnetic Bucky magnetic balls.

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