3D printed integrated acetabular reconstruction prosthesis system and preparation method thereof

Abstract

The present invention discloses a 3D printed integrated acetabular reconstruction prosthesis system and a preparation method thereof. It relates to the field of 3D printing technology, including: reconstructing a three-dimensional model of bilateral hip joints, trimming the edge of the affected acetabulum, and using mirror operation to create a supplementary model of the acetabulum defect on the affected side; merging the supplementary model with the acetabular cup model into an integrated acetabular prosthesis; designing an intraoperative positioning guide plate, reserved fixing screw holes on the inner wall of the acetabular cup, and a locking device for the acetabular cup and liner according to the integrated acetabular prosthesis and acetabular anatomy; structurally optimizing the integrated acetabular prosthesis model and imitating the porous treatment of the trabecular structure; and preparing an integrated acetabular prosthesis system based on 3D printing technology. The present invention provides an integrated acetabular reconstruction prosthesis system that restores the rotation center of the acetabulum to the anatomical position, establishes a normal joint activity mechanism, restores the structural integrity of the acetabulum, and simultaneously solves a large range of bone defects, and has good mechanical support and initial stability.

Description

Technical Field

[0001] The present invention relates to the technical field of 3D printing, and in particular to a 3D printed integrated acetabular reconstruction prosthesis system for hip replacement or hip revision surgery for large-scale acetabular defects and a preparation method thereof. Background Art

[0002] Artificial hip replacement is a safe and effective means of treating hip joint diseases. However, some patients need hip revision surgery due to various reasons such as prosthesis loosening, joint instability and joint infection. Conventional acetabular prostheses cannot solve the large-scale, irregular anatomical bone defects of the acetabulum caused by osteolysis, infection, etc. after hip replacement, and the reconstruction effect of the acetabular structure is directly related to the success or failure of the operation.

[0003] In the past, the only way to reconstruct acetabular wall defects was through oversized acetabular cups, metal spacers, and bone transplants. However, if the acetabulum is a large bone defect, and the anterior and posterior walls, acetabular roof, or inner wall of the acetabulum are damaged, the traditional method is to use metal spacers, bone blocks, and acetabular cups to reconstruct the joint. However, multi-component fixation cannot provide good initial stability, and there is the possibility of micro-motion and loosening between components, which cannot guarantee the long-term stability of the prosthesis after reconstruction. Therefore, repairing the acetabulum with severe bone defects, restoring its normal anatomical shape, and meeting the mechanical support strength are all very complex issues.

[0004] The size and shape of each person's acetabular bone defect are different. 3D printing technology can be customized according to the patient's own anatomical structure, and a personalized patch can be prepared according to the size and shape of the acetabular bone defect. However, the personalized acetabular defect patch designed using 3D printing technology also needs to be fixed to the acetabular cup, and a liner needs to be placed in the acetabular cup, that is, multiple components need to be fixed and connected. However, multi-component fixation will cause looseness and micro-movement between the fixings, and the support and stability are not very good. Moreover, since a grinding drill is needed to clean the necrotic bone and sclerotic bone in the acetabular defect during the actual operation, the cleaned acetabulum cannot match the personalized acetabular patch designed before the operation, and the surgical operation is complicated.

[0005] Therefore, designing an acetabular reconstruction prosthesis system that can repair various types of acetabular defects is a technical problem that needs to be solved urgently. Summary of the invention

[0006] In view of this, the present invention provides a 3D printed integrated acetabular reconstruction prosthesis system and a preparation method thereof, which can restore the rotation center of the acetabulum to the anatomical position, establish a normal joint movement mechanism, restore the structural integrity of the acetabulum, and simultaneously solve large-scale bone defects without the need for bone grafting or only a small amount of bone grafting. It has good mechanical support and initial stability and has important clinical application value.

[0007] In order to solve the above technical problems, the technical solution adopted by the present invention is:

[0008] In one aspect, the present invention provides a method for preparing a 3D printed integrated acetabular reconstruction prosthesis system, the method comprising:

[0009] Step 1: collecting thin-slice CT image data of the patient's hip joint and creating a bilateral hip joint three-dimensional model based on the thin-slice CT image data;

[0010] Step 2: using the bilateral hip joint three-dimensional model, performing anatomical measurement and analysis on the acetabulum of the healthy side and the affected side, trimming the defective acetabulum edge, and simulating the use of an acetabular rasp to remove necrotic bone and sclerotic bone around the acetabulum, so that the trimmed defect shape is hemispherical;

[0011] Step 3: Based on the anatomical features of the acetabulum on the healthy side, a mirror image operation is performed with the mid-sagittal position of the pelvis as a reference to obtain a three-dimensional model of the acetabulum defect on the affected side;

[0012] Step 4, measuring the diameter of the femoral head on the affected side, and determining the size of the acetabular cup according to the diameter of the femoral head on the affected side; determining the type of product to be used during the operation according to the patient's bone morphology and quality, and drawing a three-dimensional model of the acetabular cup according to the selected product type and the size of the acetabular cup;

[0013] Step 5, determining the position of the acetabulum center point according to the supplementary three-dimensional model of the acetabulum defect on the affected side; placing the acetabulum cup three-dimensional model in a standard position so that the center point of the acetabulum cup three-dimensional model coincides with the acetabulum center point, and determining the anteversion angle, abduction angle and acetabular rotation center of the acetabulum cup three-dimensional model;

[0014] Step 6: According to the position of the acetabulum center point, the affected-side acetabulum defect supplement three-dimensional model and the acetabular cup three-dimensional model are combined into an integrated acetabular prosthesis three-dimensional model by using Boolean operation;

[0015] Step 7, according to the patient's bone mass, screw holes are reserved at places where the bone mass of the ilium, ischium, and pubic ramus is greater than the preset value, the contact surface between the integrated prosthesis and the soft tissue, the contact surface with the liner kit, and the reserved screw holes are respectively treated with thick solid, and the remaining parts are treated with trabecular porous structure, and the manufacturability of the surface smoothness and structural support treatment of the three-dimensional model of the integrated acetabular prosthesis is optimized based on computer-aided technology;

[0016] Step 8: Prepare an optimized three-dimensional model of the integrated acetabular prosthesis based on 3D printing technology to obtain a 3D printed integrated acetabular reconstruction prosthesis system.

[0017] Furthermore, after obtaining the three-dimensional model of the acetabulum defect supplement on the affected side, the method further includes:

[0018] Design the acetabular positioning guide plate used during the operation, extract the bone surface from the edge of the defect supplement module to the anterior superior iliac spine on the affected side, and evenly expand the thickness by 2mm outward to generate a solid guide plate; assist in determining the grinding and filing range during the operation to ensure that the grinding and filing range is consistent with the preoperative trimming design;

[0019] The acetabulum positioning guide is prepared based on 3D printing technology.

[0020] Furthermore, the acetabulum positioning guide plate is fixed to the defective acetabulum edge with the anterior inferior iliac spine as a reference point, the guide plate is closely fitted to the ilium surface, and the guide plate is reserved with a Kirschner wire fixation hole for fixation to the acetabulum edge.

[0021] Furthermore, after drawing the 3D model of the acetabular cup, the method further includes:

[0022] The corresponding acetabular cup locking structure is designed according to the type of liner to be used to ensure that the inner wall or edge structure of the acetabular cup can be completely locked with the liner kit to be used during the operation.

[0023] Furthermore, the diameter of the screw hole is 6 mm.

[0024] Furthermore, the contact surface between the integrated prosthesis and the soft tissue, the contact surface with the liner kit, and the preset range of the reserved screw holes are respectively processed with thick solids, including:

[0025] The contact surface between the integrated prosthesis and the soft tissue and lining kit is processed with 2mm thick solid;

[0026] The reserved screw holes are within the range of 0.5mm-3mm and are solid with a thickness of 1.5mm.

[0027] Furthermore, the treatment of the porous structure of trabeculae includes:

[0028] The pre-generated porous trabecular bone structure model is intercepted to obtain a regular hexahedral porous trabecular bone model; based on the hexahedral porous trabecular bone model, a plurality of porous structures are generated inside the integrated acetabular prosthesis model.

[0029] Furthermore, before preparing the optimized integrated acetabular prosthesis three-dimensional model based on 3D printing technology, it also includes:

[0030] Finite element analysis was performed on the 3D pelvic model and the 3D model of the integrated acetabular prosthesis to obtain the stress distribution analysis results of the load-bearing position in two simulated states: before and after acetabular repair.

[0031] Compare the two load-bearing stress distribution analysis results. If the load-bearing stress distribution analysis results corresponding to the acetabulum repair meet the set stress distribution uniformity conditions and meet the biomechanical requirements of the corresponding materials, prepare the optimized integrated acetabular prosthesis three-dimensional model based on 3D printing technology; otherwise, return to step 3 to recreate the acetabulum supplementary material three-dimensional model.

[0032] Furthermore, after step 8, the following steps are further included:

[0033] The acetabulum entity, the integrated acetabulum prosthesis entity, and the acetabulum positioning guide that have been repaired and optimized are prepared based on 3D printing technology to perform simulated surgery to verify the matching degree between the entities and ensure that the integrated acetabulum prosthesis and the repaired acetabulum defect achieve structural press-fit stability.

[0034] On the other hand, the present invention further provides an integrated acetabular reconstruction prosthesis system based on 3D printing technology, and the integrated acetabular reconstruction prosthesis system is prepared according to the preparation method of the 3D printing integrated acetabular reconstruction prosthesis system.

[0035] Compared with the prior art, the present invention adopts the above technical solution and has the following beneficial effects:

[0036] 1) The current existing technology uses 3D printing technology to design acetabular defect patches and acetabular cups for fixation, but multi-component fixation will cause looseness and micro-motion between the fixing parts. The present invention innovatively proposes to use 3D printing technology to integrate the acetabular defect patch and the acetabular cup prosthesis into an integrated prosthesis system, which can not only restore the structural integrity of the acetabulum, but also reduce micro-motion and looseness between multi-component fixations.

[0037] 2) The construction method of the 3D printed integrated acetabular reconstruction prosthesis system of the present invention can restore the rotation center of the hip joint to the normal anatomical position, and is verified by finite element analysis to better meet normal biomechanical requirements; based on preoperative CT images, the acetabular edge is trimmed, excess necrotic bone and sclerotic bone are removed, and the defect patch is made into a more regular hemispherical shape, which can better achieve the press-fit stability between the prosthesis and the host bone during the operation and reduce the risk of prosthesis loosening after surgery.

[0038] 3) The method for constructing the 3D printed integrated acetabular reconstruction prosthesis system of the present invention can realize the matching planning between the prosthesis and the host bone in the software before the operation, so as to make the operation precise, personalized and simplified, reduce the complexity of the operation, improve the accuracy of the operation, and at the same time reduce the operation time and shorten the postoperative recovery time.

[0039] 4) The 3D printed integrated acetabular reconstruction prosthesis system of the present invention adopts a porous trabecular bone structure, which is conducive to bone ingrowth at the implant-bone interface, allowing fusion between the prosthesis and the host bone to ensure the long-term stability of the implant.

[0040] 5) The present invention provides a method for designing an intraoperative guide plate, which is designed based on a three-dimensional model of the patient's ilium and has good adhesion to the ilium. It can help to more quickly determine the intraoperative acetabular grinding range, shorten the operation time, and place the prosthesis more accurately, which is beneficial to postoperative functional recovery.

[0041] 6) The locking device is designed on the edge of the acetabular cup prosthesis in the present invention, and the locking device can be personalized according to the liner product model selected before surgery, so that the liner and the acetabular cup are fixed more firmly.

[0042] 7) The position of the prosthesis fixing screws in the present invention is personalized. According to the patient's bone mass, screw holes can be reserved in the ilium, ischium, and pubic ramus where the bone mass is abundant, so that the prosthesis fixing position is more accurate and the effect is more solid. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0044] Figure 1 A flow chart of the preparation of a 3D printed integrated acetabular reconstruction prosthesis system in an embodiment of the present invention;

[0045] Figure 2 A schematic diagram of a 3D printed integrated acetabular reconstruction prosthesis system in an embodiment of the present invention;

[0046] Figure 3 A schematic diagram of another 3D printed integrated acetabular reconstruction prosthesis system according to an embodiment of the present invention;

[0047] Figure 4 A schematic diagram of an intraoperative positioning guide at a certain angle in an embodiment of the present invention;

[0048] Figure 5 This is a schematic diagram of an intraoperative positioning guide at another angle in an embodiment of the present invention;

[0049] Figure 6 A schematic diagram of the placement position of a 3D printed integrated acetabular reconstruction prosthesis system in the acetabulum at one angle in an embodiment of the present invention;

[0050] Figure 7FIG. 1 is a schematic diagram of the placement position of a 3D printed integrated acetabular reconstruction prosthesis system in the acetabulum at another angle in an embodiment of the present invention. DETAILED DESCRIPTION

[0051] In order to enable those skilled in the art to better understand the scheme of the present invention, the technical scheme in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0052] It should be noted that the terms "first", "second", etc. in the specification and claims of the present invention and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged where appropriate, so that the embodiments of the present invention described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0053] like Figure 1 As shown, a method for preparing a 3D printed integrated acetabular reconstruction prosthesis system provided in an embodiment of the present invention comprises the following specific steps:

[0054] Step 1: Collect thin-layer CT image data of the patient's hip joint and create a three-dimensional model of bilateral hip joints based on the thin-layer CT image data.

[0055] Step 2: Using the three-dimensional model, perform anatomical measurement and analysis on the healthy and affected acetabulum, trim the defective acetabulum margin, and simulate the use of an acetabular rasp to remove necrotic bone and sclerotic bone around the acetabulum, so that the trimmed defect shape is similar to a more regular hemispherical shape.

[0056] Step 3: According to the anatomical features of the acetabulum on the healthy side, a mirror operation is performed with the mid-sagittal plane of the pelvis as a reference to obtain a three-dimensional model of the acetabulum defect supplementation on the affected side; if the patient does not have a healthy acetabulum, the acetabulum model of other healthy patients is used to create a three-dimensional model of the acetabulum defect supplementation.

[0057] Step 4. Based on the 3D model of acetabular defect supplementation, design the acetabular positioning guide for use during the operation. Extract the bone surface from the edge of the defect supplementation module to the anterior superior iliac spine on the affected side, and evenly expand the thickness outward by 2mm to generate a solid guide. Assist in determining the intraoperative grinding and filing range to ensure that the grinding and filing range is consistent with the preoperative trimming design.

[0058] Step 5: Measure the diameter of the femoral head, and determine the inner diameter of the acetabular cup by the femoral head diameter + 2mm, and the outer diameter of the acetabular cup by the inner diameter + 8mm. Select the type of liner and femoral head prosthesis product to be used according to the shape and quality of the patient's affected hip, and draw a three-dimensional model of the acetabular cup based on the selected product type and the acetabular cup size determined above.

[0059] Step 6: Design the acetabular cup and liner locking device. The corresponding acetabular cup locking structure can be designed according to the type of liner to be used to ensure that the inner wall or edge structure of the acetabular cup and the liner kit to be used during the operation can be completely locked. The structure of the locking device, such as a 1mm wide annular groove structure, a semicircular or rectangular groove structure, etc., all locking structures matching the liner are within the scope of protection of the present invention and are not specifically limited here.

[0060] Step 7: Supplement the three-dimensional model according to the acetabulum defect and determine the position of the acetabulum center point. Place the acetabulum cup prosthesis model in a standard position so that the center point of the acetabulum cup model coincides with the center point of the affected acetabulum, and determine its anteversion angle, abduction angle and acetabulum rotation center.

[0061] Step 8: Use Boolean operations to integrate and merge the modified personalized acetabular defect supplement model and the acetabular cup prosthesis model into a personalized integrated acetabular prosthesis.

[0062] Step 9. According to the patient's bone mass, 6mm diameter screw holes are reserved in the ilium, ischium, and pubic ramus where the bone mass is abundant (the bone mass is greater than 15mm), and 1.5mm thick solid treatment is adopted around the reserved screw holes (within the range of 0.5mm-3mm). The contact surface between the integrated prosthesis and the soft tissue and the liner kit is treated with a 2mm thick solid. The remaining part is treated with a porous structure of trabeculae, and the average porosity is 50-70%. The manufacturability optimization of the integrated acetabular prosthesis three-dimensional model is performed based on computer-aided technology. Manufacturability optimization includes at least: surface smoothing and structural support processing. In addition, the optimization also includes: model repair such as model refinement, bone surface defect repair, rapid smoothing, and precise surface function.

[0063] Step 10: Perform finite element analysis on the pelvic three-dimensional model and the integrated acetabular prosthesis three-dimensional model.

[0064] The boundary conditions of the sacroiliac joint and pubic symphysis were set as full freedom constraints in the finite element analysis software. A vertical upward reaction force representing 2.75 times the individual mass was applied to the center of the femoral head and the center of the femoral head prosthesis matched with the acetabular cup to simulate the state of single-leg standing. The stress distribution analysis results of the load-bearing position were obtained in two simulated states before and after acetabular repair.

[0065] Step 11, comparing the two load-bearing stress distribution analysis results, if the load-bearing stress distribution analysis result corresponding to the acetabulum repair meets the set stress distribution uniformity condition and meets the biomechanical requirements of the corresponding material, proceed to the next step; otherwise, return to step 3 to recreate the acetabulum defect supplement three-dimensional model;

[0066] Step 12: Based on 3D printing technology, prepare a three-dimensional model of the integrated acetabular prosthesis and an acetabular positioning guide after repair and optimization;

[0067] Printing materials include but are not limited to tantalum, titanium, titanium alloys, polymer materials, and bioceramics.

[0068] Step 13: Prepare the acetabulum entity, integrated acetabulum prosthesis entity, and acetabulum positioning guide after repair optimization based on 3D printing technology to perform simulated surgery to verify the matching degree between the entities, and ensure that the integrated acetabulum prosthesis and the repaired acetabulum defect achieve structural press-fit stability.

[0069] like Figure 2 and Figure 3 As shown, a 3D printing integrated acetabular reconstruction prosthesis system provided by an embodiment of the present invention includes a personalized customized acetabular defect patch 1 and an acetabular cup 2. The defect patch 1 is hemispherical in shape, which is convenient for press-fitting with the affected acetabulum after grinding and drilling. The defect patch 1 and the acetabular cup 2 are an integrated structure prepared by 3D printing. In addition, the contact surface between the prosthesis system and the soft tissue and the liner kit is treated with a 2mm thick solid, and the remaining part is treated with a trabecular porous structure with an average porosity of 50-70%. The edge of the acetabular cup 2 can be personalized and designed with a locking device 21 corresponding to the liner. 6mm diameter screw holes 3 can be personalized and reserved in the ilium, ischium, and pubic branches according to the patient's bone mass, and a 1.5mm thick solid treatment is adopted around the reserved screw holes. The printing material of the acetabular defect patch 1 and the acetabular cup 2 is tantalum.

[0070] Surgical guides used in conjunction with the 3D printed integrated acetabular reconstruction prosthesis system, such as Figure 4 and Figure 5As shown, it uses the anterior inferior iliac spine of the affected hip as a reference point, 3 is tightly attached to the anterior inferior iliac spine, the guide body 1 can be closely attached to the ilium, and two Kirschner wire catheters are reserved for inserting Kirschner wires to temporarily fix the guide to the ilium. The drill can trim the acetabulum along the lower edge 4 of the guide. The positioning guide can be made of polymer biomaterials, printed based on 3D printing technology and integrally formed.

[0071] During hip replacement surgery, the soft tissue above the acetabulum defect is first stripped away, and the positioning guide is temporarily installed at the predetermined position using a Kirschner wire; the necrotic bone and sclerotic bone in the acetabulum defect are then cleaned with a drill. After the drill edge is flush with the lower edge of the guide, the acetabulum is trimmed, and the 3D printed integrated acetabulum reconstruction prosthesis system is placed in the acetabulum, compacted, pressed, fixed with screws, and the liner is placed. Figure 6 , Figure 7 shown.

[0072] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A method for preparing a 3D printed integrated acetabular reconstruction prosthesis system, characterized in that: The method comprises: Step 1: collecting thin-slice CT image data of the patient's hip joint and creating a bilateral hip joint three-dimensional model based on the thin-slice CT image data; Step 2: using the bilateral hip joint three-dimensional model, performing anatomical measurement and analysis on the acetabulum of the healthy side and the affected side, trimming the defective acetabulum edge, and simulating the use of an acetabular rasp to remove necrotic bone and sclerotic bone around the acetabulum, so that the trimmed defect shape is hemispherical; Step 3: Based on the anatomical features of the acetabulum on the healthy side, a mirror image operation is performed with the mid-sagittal position of the pelvis as a reference to obtain a three-dimensional model of the acetabulum defect on the affected side; Step 4, designing an acetabular positioning guide plate used in conjunction with the operation, extracting the bone surface from the edge of the defect supplementary module to the anterior superior iliac spine of the affected side, and uniformly expanding the thickness outward by 2 mm to generate a physical guide plate; assisting in determining the grinding and filing range during the operation, so that the grinding and filing range is consistent with the preoperative finishing design; preparing the acetabular positioning guide plate based on 3D printing technology; the acetabular positioning guide plate uses the anterior inferior iliac spine as a reference point and is fixed to the defective acetabulum edge, the guide plate is closely fitted to the ilium surface, and the guide plate is reserved for a Kirschner wire fixation hole fixed to the acetabulum edge; Step 5, measure the diameter of the femoral head on the affected side, determine the inner diameter of the acetabular cup by the femoral head diameter + 2mm, and determine the outer diameter of the acetabular cup by the inner diameter + 8mm; determine the type of product to be used during the operation according to the patient's bone morphology and quality, and draw a three-dimensional model of the acetabular cup according to the selected product type and the size of the acetabular cup; Step 6: Design a corresponding acetabular cup locking structure according to the type of liner to be used, ensuring that the inner wall or edge structure of the acetabular cup can be completely locked with the liner kit to be used during the operation; Step 7, determining the position of the acetabulum center point according to the 3D supplementary model of the acetabulum defect on the affected side; placing the acetabulum cup 3D model in a standard position so that the center point of the acetabulum cup 3D model coincides with the acetabulum center point, and determining the anteversion angle, abduction angle and acetabular rotation center of the acetabulum cup 3D model; Step 8, according to the position of the acetabulum center point, the affected-side acetabulum defect supplement three-dimensional model and the acetabular cup three-dimensional model are combined into an integrated acetabular prosthesis three-dimensional model by using Boolean operation; Step 9, according to the patient's bone mass, screw holes are reserved at the places where the bone mass of the ilium, ischium and pubic ramus is greater than the preset value, and the contact surface between the integrated prosthesis and the soft tissue and the liner kit is treated with a 2mm thick solid; the reserved screw holes are treated with a 1.5mm thick solid in the range of 0.5mm-3mm, and the remaining parts are treated with a trabecular porous structure, and the manufacturability of the surface smoothness and structural support treatment of the three-dimensional model of the integrated acetabular prosthesis is optimized based on computer-aided technology; the diameter of the screw hole is 6mm; the trabecular porous structure treatment includes: intercepting a pre-generated porous trabecular structure model to obtain a regular hexahedral porous trabecular model; based on the hexahedral porous trabecular model, a number of porous structures are generated inside the integrated acetabular prosthesis model; Step 10, perform finite element analysis on the pelvic three-dimensional model and the integrated acetabular prosthesis three-dimensional model, apply a vertical upward reaction force representing 2.75 times the individual mass at the center of the femoral head and the center point of the femoral head prosthesis matched with the acetabular cup, respectively, to simulate the state of a single-leg standing posture, and obtain the load-bearing stress distribution analysis results under two simulated states before and after the acetabular repair; compare the two load-bearing stress distribution analysis results, if the load-bearing stress distribution analysis results corresponding to the acetabular repair meet the set stress distribution uniformity conditions and meet the biomechanical requirements of the corresponding materials, then prepare an optimized integrated acetabular prosthesis three-dimensional model based on 3D printing technology to obtain a 3D printed integrated acetabular reconstruction prosthesis system; the integrated prosthesis system includes an acetabular defect patch and an acetabular cup prosthesis; otherwise, return to step 3 to recreate the acetabular supplementary material three-dimensional model; Step 11, based on 3D printing technology, the acetabulum entity, the integrated acetabulum prosthesis entity, and the acetabulum positioning guide after the repair optimization treatment are prepared to perform simulated surgery to verify the matching degree between the entities, and ensure that the integrated acetabulum prosthesis and the repaired acetabulum defect achieve structural press-fit stability.

2. An integrated acetabular reconstruction prosthesis system based on 3D printing technology, wherein the integrated acetabular reconstruction prosthesis system is prepared according to the preparation method of the 3D printed integrated acetabular reconstruction prosthesis system according to claim 1.

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