Quality control method and quality control equipment for traditional Chinese medicine ointment

Abstract

The present invention discloses a quality control method and quality control equipment for Chinese medicine ointment, which belongs to the technical field of Chinese medicine, including the preparation of Chinese medicine ointment, the processing of special medicinal materials and auxiliary materials, and the determination of relevant quality indicators of Chinese medicine ointment. The method includes the following steps: soaking, decoction, precipitation, filtration, concentration, ointment collection and drying. The present invention aims at the problems existing in the quality control of existing Chinese medicine ointments, treats different medicinal materials and auxiliary materials in different ways, avoids the quality problems of Chinese medicine ointment during the treatment process, and effectively improves its quality level; detects the Chinese medicine ointment, measures the relative density, water content, dynamic viscosity and other related indicators of the prepared Chinese medicine ointment, establishes the quality control standard of Chinese medicine ointment, thereby helping to effectively control the quality of finished products in production; provides a method for solving the problem of easy to sticky bottom during decoction, avoids the quality problems of Chinese medicine ointment during the treatment process, and improves the qualified rate of finished products in production.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and in particular to a quality control method and quality control equipment for traditional Chinese medicine ointments. Background Art

[0002] Paste, also known as paste prescription, is a type of Chinese medicine dosage form. As a Chinese medicine, paste has the advantages of being delicious and tasty. It is also easy to take and is popular among patients, so it is widely used.

[0003] The existing Chinese publication number CN104111295A is a quality control method for a Chinese medicine preparation. The invention provides a quality control method for a Jinchai preparation, which includes content determination, or also includes an identification method, which requires that the product contains no less than 4.00 mg of honeysuckle in terms of chlorogenic acid (C16H18O9) per grain, and no less than 16.00 mg of scutellaria in terms of baicalin (C23H28O11) per grain. The method has the characteristics of stability and good reproducibility, can effectively supervise production, control the quality of the variety, and ensure the stability of product quality.

[0004] The prior art provides a method for detecting finished drugs and monitors the finished drugs, but does not perform quality control during the manufacturing process, and is unable to improve the yield of the product. The preparation of Chinese herbal ointments involves a variety of medicinal materials and auxiliary materials, and different medicinal materials and auxiliary materials require different processing methods, otherwise the quality of the finished product of the Chinese herbal ointment will be affected, affecting the quality rate of the finished product of the Chinese herbal ointment. In the quality inspection of the Chinese herbal ointment, it is necessary to detect relevant indicators of a variety of Chinese herbal ointments to help effectively control the quality of the finished product in production. The soaking time and soaking effect play a vital role in supporting the drug, which can effectively improve the yield of the product and save medicinal material resources. Moreover, in the process of preparing the Chinese herbal ointment, the concentration link needs to remove the surface foam, and the existing defoaming method is to scrape the foam from the surface of the medicine liquid with a container, and in the defoaming process, part of the medicine liquid will be moved out of the concentration cylinder together with the foam, resulting in a waste of medicine liquid. Summary of the invention

[0005] The embodiment of the present invention provides a quality control method and quality control equipment for a traditional Chinese medicine ointment to solve the above technical problems.

[0006] The embodiment of the present invention adopts the following technical scheme: a quality control device for Chinese medicine ointment, comprising a soaking box, a decoction mechanism, a sedimentation tank, a stainless steel filter screen, a concentration cylinder, a foam removal mechanism and an ointment collection mechanism, wherein the decoction mechanism is installed on the side of the soaking box, the sedimentation tank is installed on the side of the decoction mechanism, the stainless steel filter screen is installed in the sedimentation tank, the concentrating cylinder is installed on the side of the stainless steel filter screen and is connected to the stainless steel filter screen, a curved panel is provided in the concentrating cylinder, the foam removal mechanism is installed in the concentrating cylinder, and the ointment collection mechanism is installed on the side of the concentrating cylinder and is connected to the concentrating cylinder.

[0007] Furthermore, the defoaming mechanism includes a screw slide, a connecting frame, a driving mechanism, a defoaming arc frame, a defoaming filter and a handle, the screw slide is installed on the concentrating cylinder, the connecting frame is installed on the slide of the screw slide, the driving mechanism is rotatably installed on the connecting frame, the defoaming arc frame is installed on the driving mechanism, the defoaming arc frame is both slidingly and rotatably matched with the concentrating cylinder, one end of the defoaming filter is hinged on the defoaming arc frame, the handle is installed on the other end of the defoaming filter, and the defoaming arc frame is provided with a drain port.

[0008] Furthermore, the driving mechanism includes a driving motor, a driving rotating rod, a driving slot plate and a driving rotating block, the driving motor is installed on a connecting frame, one end of the driving rotating rod is installed on the main shaft of the driving motor, the driving slot plate is rotatably installed on the connecting frame, one end of the driving rotating block is rotatably installed on the connecting frame and one end of the driving rotating block is connected to the defoaming arc frame, the other end of the driving rotating rod is slidably clamped on the driving slot plate, and the other end of the driving rotating block is slidably clamped on the driving slot plate.

[0009] Furthermore, a foam collecting box is provided on the side wall of the concentrating cylinder, the foam collecting box is communicated with the concentrating cylinder, and a reflux filter is provided between the foam collecting box and the concentrating cylinder.

[0010] Furthermore, a method for quality control of a Chinese medicine ointment includes the preparation of the Chinese medicine ointment, the processing of special medicinal materials, the processing of auxiliary materials, and the determination of the quality of the Chinese medicine ointment. The preparation of the Chinese medicine ointment includes the following steps:

[0011] Soaking: Add water 3-5cm above the medicinal surface, about 12 times the volume of the original medicinal material, and soak for more than 8 hours. During the soaking step, the quality of the medicinal material is controlled;

[0012] Decoction: Heat to boiling over high heat, then change to low heat, keep boiling, decoct for 2 hours, sieve out the filtrate with a 60-80 mesh sieve after decoction, continue to add 8 times the volume of the original medicinal material for a second decoction, decoct for 90 minutes, sieve out the filtrate with a 60-80 mesh sieve after decoction, continue to add 6 times the volume of the original medicinal material for a third decoction, decoct for 1 hour, combine the decoctions after decoction, and let them stand for precipitation;

[0013] Sedimentation: The decoction is filtered through an 80-mesh screen, combined, and allowed to settle for 8 to 12 hours, so that the fine particles of drug residue and impurities in the drug solution can be fully removed, making the paste taste delicate;

[0014] Filtration: The precipitated liquid is filtered using a 200-mesh stainless steel filter screen;

[0015] Concentration: put the liquid medicine filtered through a 200-mesh stainless steel filter into a copper pot and heat it, removing the floating foam at any time, until the liquid medicine becomes thick and sticky, and use bamboo strips to pick up the liquid medicine into a line and let it flow down, and the "clear paste" is obtained. The density of the clear paste is 1.25-1.27;

[0016] Collecting the paste: Heat the clear paste with a slow fire, stirring constantly, add the pre-treated glue, sugar and other auxiliary materials into the clear paste, and finally add the fine precious medicine juice. When heated, it will form a honeycomb-like "overturning bucket cloud". At this time, the paste (test sample) is about to be completed. It should be stirred frequently. Lift the stirring rod to see that the paste (test sample) is at a right angle of 90°. The paste (test sample) drips downward into a triangle or the paste (test sample) is clamped between the index finger and the thumb, and a filament of about 2 cm can be pulled out. Or take a drop of the paste (test sample) and drop it into cold water. Check the state of beads with the naked eye. At this time, the paste (test sample) is completed. Put it into a container and cool it;

[0017] Drying the paste: The indoor environment for drying the paste needs to be disinfected with ultraviolet light for 1 hour, the temperature should be controlled below 20°C, and the relative humidity should be controlled at 45% to 75%. The container containing the paste (test sample) needs to be wiped and disinfected with 75% alcohol and kept dry. After the paste is completely cooled, the lid containing the paste (test sample) should be closed.

[0018] The special medicinal materials include fresh dendrobium officinale, yam, lotus seeds, walnut meat, black sesame, ginseng and saffron, etc. The special medicinal materials processing method is as follows:

[0019] Fresh Dendrobium candidum: squeeze the juice, add the concentrated juice to the paste, and decoct the residue with other medicines;

[0020] Chinese yam and lotus seeds: stir-fry over low heat until the surface of the medicine turns slightly brown, turn off the heat, take out and put it at room temperature of 25℃, let it cool down and crush or mash it into a paste, add it to the paste liquid and cook together;

[0021] Walnut meat: Remove the skin and stir-fry over low heat until fragrant, or bake in an oven until the surface turns light brown and has an aroma. Sieve and let cool, then grind into coarse powder and pass through a 20-mesh sieve. When collecting the paste, add it to the paste liquid and cook for about 0.5h;

[0022] Black sesame: remove impurities from the herbs, stir-fry over low heat until there is a popping sound and the aroma escapes, take out and let cool, grind into coarse powder, add to the paste liquid and cook for 0.5h;

[0023] Ginseng and saffron: These are precious herbs and should be decocted separately. The resulting juice should be added to other creams in the concentration step for concentration. If necessary, add the original powder of the herbs. Dry the herbs in an oven at 60°C for 60 minutes, crush them, and sieve them through a 200-mesh stainless steel sieve. Add them to the cream in the cream collection step.

[0024] The processing method of the auxiliary materials is as follows:

[0025] Honey: After the honey is heated to boiling, filter it through an 80-mesh stainless steel sieve while it is hot, and then heat it until light yellow, shiny, and evenly bubbling bubbles appear. It is sticky when you rub it with your hands, and no white threads appear when you separate two fingers. At this time, the water content of the honey is 14%-16%, and the relative density is about 1.37;

[0026] Rock sugar and granulated sugar: add 1 times the amount of water to dissolve them, heat and refine until the sugar liquid is golden and shiny;

[0027] Brown sugar: Brown sugar contains more impurities, so generally add twice the amount of water as that of brown sugar, heat it to a boil, let it stand, remove the precipitate and set aside;

[0028] Maltose: After heating to boiling, the sugar liquid is golden yellow with evenly bubbling fine bubbles and has the unique caramel aroma of maltose;

[0029] Other flavoring agents: such as xylitol, chaste sugar, sodium cyclamate, etc., can be dissolved in water or precipitated liquid medicine at a ratio of 1:1, and then added to concentrate;

[0030] Glue: such as donkey-hide gelatin, deer antler glue, tortoise shell glue, etc., crush them and pass through a 20-mesh stainless steel sieve, add yellow wine in equal proportion to the volume of the glue, and soak for about 4 hours. Add it into the liquid medicine during the concentration stage, keep the liquid medicine boiling over low heat until the colloid is completely dissolved;

[0031] Furthermore, the steps of determining the quality of the Chinese medicine ointment are: detecting the relative density of the Chinese medicine ointment, detecting the water content of the Chinese medicine ointment, and detecting the dynamic viscosity of the Chinese medicine ointment;

[0032] The relative density detection method of the Chinese medicine ointment is as follows:

[0033] S1: Take an appropriate amount of the test sample, weigh it accurately, add water twice the volume of the test sample, weigh it accurately, mix well, and use it as the test sample solution;

[0034] S2: Determine using the pycnometer method. Take a clean, dry and accurately weighed pycnometer, fill it with the test sample (the temperature should be below 20°C), install a thermometer (there should be no bubbles in the bottle), place it in a 20°C water bath for several minutes to make the temperature of the contents reach 20°C, remove the liquid overflowing the side tube with filter paper, immediately cover it, then take the pycnometer out of the water bath, wipe the outside of the pycnometer with filter paper, accurately weigh it, subtract the weight of the pycnometer, and after obtaining the weight of the test sample, pour out the test sample, wash the pycnometer, fill it with freshly boiled cold water, and then measure the weight of water at the same temperature according to the above method, and calculate according to the following formula;

[0035]

[0036] Where W1 is the weight of the test solution in the pycnometer, in g; W2 is the weight of the water in the pycnometer, in g.

[0037] The water content detection method of the traditional Chinese medicine ointment is to use the moisture determination method-drying method to determine: take 2-5g of the test sample, spread it flat in a flat weighing bottle that has been dried to constant weight, with a thickness of no more than 5mm, accurately weigh it, open the bottle cap and dry it at 100-105°C for 5 hours, cover the bottle cap, move it to a dryer, let it cool for 30 minutes, accurately weigh it, and then dry it at the above temperature for 1 hour, let it cool, and weigh it until the difference between two consecutive weighings does not exceed 5mg. According to the lost weight, calculate the water content (%) in the test sample;

[0038] The dynamic viscosity detection method of the Chinese medicine ointment is as follows:

[0039] Step 1: Take samples first, and test the paste (test product) when it is about to come out of the pot (95℃);

[0040] Step 2: Use a rotational viscometer to measure the dynamic viscosity. Select a suitable rotor (rotor No. 2) and immerse it in the test solution. Make the rotor rotate at a certain speed (12 r / min -1 ) rotates and the dynamic viscosity is read directly in a rotational viscometer.

[0041] Furthermore, the bottom of the soup may become scorched during the cooking process. To address this problem, the following measures can be taken:

[0042] (1) When preparing paste prescriptions, put the drugs with particularly high viscosity or high sugar content, such as Rehmannia glutinosa, Polygonatum sibiricum, Cistanche deserticola, and Asparagus cochinchinensis, separately and add them to the top layer of the decoction container last during soaking to prevent them from sticking to the bottom of the pot and producing a burnt smell.

[0043] (2) Stir frequently during the decoction process to speed up heat circulation, closely observe the changes in the decoction liquid and the smell of the liquid, and control the heat appropriately. Especially when the liquid is slightly boiling, stir it immediately to the bottom of the pot. At this time, stir faster, otherwise the liquid will easily overflow from the pot when it boils;

[0044] Treatment of late-added medicines in the prescription: Considering that traditional decoction and concentration time is too long, the Chinese medicinal materials that need to be added later in the prescription, such as cinnamon, amomum villosum, white cardamom, mint and other aromatic and volatile medicines, are put into disposable non-woven decoction bags and added to the concentrated solution 15 minutes before the end of the concentration process. After decoction, take out the bags to preserve the effective ingredients of the Chinese medicinal materials to the greatest extent.

[0045] Furthermore, in the soaking step, the soaking quality control method of the medicinal material comprises the following steps:

[0046] S3: Take 1kg of medicinal materials, crush them, put them into the extraction tank, add 3-6 times the amount of water as the medicinal materials and start extraction;

[0047] S4: stirring for 10-20 minutes at extraction times of 8 hours, 10 hours, 12 hours, 14 hours, 16 hours, 18 hours, 20 hours, 22 hours, and 24 hours, respectively;

[0048] S5: taking each sterol compound of the medicinal material as the detection index, taking the end point content value of each medicinal material extraction as the target value B;

[0049] S6: using a near infrared chromatograph to take samples for testing after each stirring to detect the content of each sterol compound in the extract;

[0050] S7: repeat S3, S4, and S6 multiple times, and collect near-infrared spectra;

[0051] S8: When the contents of the sterol compounds detected in S6 all reach the extraction endpoint target value, it is determined that the soaking endpoint is reached.

[0052] Furthermore, in step S6, the method for detecting the content of each sterol compound in the extract is as follows:

[0053] Step 1: Set the index data detected in step S6 for 16 hours as A, in mg / ml; assume that the detection data of each steroid compound for 16 hours are A1, A2, A3, A4, A5..., and take one steroid compound as an example, the data of multiple batches of detection are assumed to be A1a, A1b, A1c, A1d, A1e, A1f...;

[0054] Step 2: Then, according to the difference between A and B detected, the stirring time is determined to be 16 hours, and the dissolution of the index component is promoted so that the extraction end point is reached at 18 hours;

[0055] Step 3: Calculate the C value of the index, C = (BA) / B × 100%, and select the effective component with the largest C value; if BA ≤ 0, there is no need to increase the stirring time, and the increased stirring time T = e^(a·lnC+b)+c, where T is in minutes, and a, b, c are constants;

[0056] Step 4: Repeat the experiment 5 times, compare the values ​​in step S6 with the index components at the extraction endpoint, obtain the C1 and C2 values ​​before and after control for each batch, and then compare C1 and C2.

[0057] At least one of the above technical solutions adopted in the embodiments of the present invention can achieve the following beneficial effects:

[0058] First, the present invention only provides monitoring of the prepared medicines for the prior art, and does not perform quality control in the manufacturing process, and cannot improve the yield of the product. The present invention processes different medicinal materials and auxiliary materials in different ways to avoid quality problems in the quality of Chinese medicine ointments during the processing, effectively control the quality of finished products in production and improve their quality level; secondly, the relative density, water content and dynamic viscosity of the Chinese medicine ointment are detected, and the above three related indicators of the prepared Chinese medicine ointment are accurately measured, and the quality control standard of the Chinese medicine ointment is established accordingly, so as to help effectively control the quality of the finished products in production, ensure the controllable production process, ensure the safety of clinical use, and provide reliable guarantee for the stable and accurate efficacy of the product; provide a method for solving the problem of easy to paste the bottom of the decoction, avoid quality problems in the quality of the Chinese medicine ointment during the processing, and improve the quality rate of the finished products in production; at the same time, provide a quality control method in the process of soaking medicinal materials, improve the yield of Chinese medicine ointments, and save medicinal material resources.

[0059] Secondly, the defoaming mechanism is first driven by the driving mechanism to drive the defoaming arc frame and the defoaming filter to be vertically located on one side of the concentrating cylinder, and then the screw slide starts to operate, driving the driving mechanism, the defoaming arc frame and the defoaming filter to move to the inside of the concentrating cylinder. When the defoaming arc frame moves to the middle position of the concentrating cylinder, the driving mechanism will drive the defoaming arc frame and the processing filter to rotate, and the floating foam on the surface of the concentrating cylinder will be blocked by the defoaming filter, and the liquid medicine picked up with the floating foam will move to the defoaming arc frame through the defoaming filter, and then be discharged back into the concentrating cylinder through the discharge port of the defoaming arc frame, so as to promote the effective liquid medicine to return to the concentrating cylinder and avoid the waste of liquid medicine. The remaining floating foam can be cleaned up by rotating the defoaming filter to the side of the concentrating cylinder through the handle.

[0060] Thirdly, when the defoaming filter is rotated to one side of the concentrator by the handle and the defoaming is moved to the foam collecting box, some liquid medicine will be produced after the floating foam is eliminated. The liquid medicine can flow back to the concentrator through the reflux filter, thereby improving the utilization of medicinal resources and reducing the waste of resources. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] The drawings described herein are used to provide a further understanding of the present invention and constitute a part of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the drawings:

[0062] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0063] Figure 2 It is a schematic diagram of the three-dimensional structure of the concentrator cylinder of the present invention;

[0064] Figure 3 It is a three-dimensional structural schematic diagram of the defoaming mechanism of the present invention;

[0065] Figure 4 It is a three-dimensional structural schematic diagram of the driving mechanism of the present invention;

[0066] Figure 5 It is a working flow chart of the defoaming mechanism of the present invention when it is in the initial position;

[0067] Figure 6 This is a working flow diagram when the defoaming mechanism of the present invention is located in the middle of the concentration cylinder;

[0068] Figure 7 It is a working flow chart of the defoaming mechanism of the present invention when defoaming.

[0069] Reference numerals

[0070] Soaking box 1, boiling mechanism 6, sedimentation tank 9, stainless steel filter screen 4, concentration cylinder 5, defoaming mechanism 2, paste collecting mechanism 7, curved panel 8, screw slide 21, connecting frame 22, driving mechanism 3, defoaming arc frame 23, defoaming filter 24, handle 25, driving motor 31, driving rotating rod 32, driving slot plate 33, driving rotating block 34, foam collecting box 35, reflux filter 36. DETAILED DESCRIPTION

[0071] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the specific embodiments of the present invention and the corresponding drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0072] The technical solutions provided by various embodiments of the present invention are described in detail below in conjunction with the accompanying drawings.

[0073] Reference Figures 1 to 7 As shown, the embodiment of the present invention provides A quality control device for traditional Chinese medicine ointment, comprising a soaking box 1, a boiling mechanism 6, a sedimentation tank 9, a stainless steel filter screen 4, a concentration cylinder 5, a defoaming mechanism 2 and a paste collecting mechanism 7, wherein the boiling mechanism 6 is installed beside the soaking box 1, the sedimentation tank 9 is installed beside the boiling mechanism 6, the stainless steel filter screen 4 is installed in the sedimentation tank 9, the concentration cylinder 5 is installed beside the stainless steel filter screen 4 and is connected to the stainless steel filter screen 4, a curved plate 8 is provided in the concentration cylinder 5, the defoaming mechanism 2 is installed in the concentration cylinder 5, the paste collecting mechanism 7 is installed beside the concentration cylinder 5 and is connected to the concentration cylinder 5, and the defoaming mechanism 2 is installed in the concentration cylinder 5. The shrinking cylinder 5 is connected; first, the medicinal materials are added to the soaking box 1, and the amount of water added is 3-5cm more than the medicinal surface. The soaking time is more than 8 hours, and then the decoction mechanism 6 is added, and the high heat is heated to boiling, and then the low heat is changed to keep boiling state, and the medicinal materials are decocted. After decoction, they are put into the sedimentation tank 9, and allowed to settle. The stainless steel filter screen 4 filters the medicinal liquid and then adds it into the concentration cylinder 5 for heating. The defoaming mechanism 2 cooperates with the curved plate 8 to remove the floating foam at any time. After concentration, the ointment collecting mechanism 7 is added to collect the ointment, and then the ointment is moved to the drying environment for drying.

[0074] Preferably, the defoaming mechanism 2 includes a screw slide 21, a connecting frame 22, a driving mechanism 3, a defoaming arc frame 23, a defoaming filter 24 and a handle 25, the screw slide 21 is installed on the concentration cylinder 5, the connecting frame 22 is installed on the slide of the screw slide 21, the driving mechanism 3 is rotatably installed on the connecting frame 22, the defoaming arc frame 23 is installed on the driving mechanism 3, the defoaming arc frame 23 and the concentration cylinder 5 are both slidably matched and rotatably matched, one end of the defoaming filter 24 is hinged on the defoaming arc frame 23, the handle 25 is installed on the other end of the defoaming filter 24, and the defoaming arc frame 23 is provided with a drain port; the defoaming mechanism 2 is first driven by the driving mechanism 3 to drive the defoaming arc frame 23 and the defoaming filter 24 vertically The defoaming arc frame 23 is directly located at one side of the concentrating cylinder 5, and then the screw slide 21 starts to operate, driving the driving mechanism 3, the defoaming arc frame 23 and the defoaming filter screen 24 to move toward the inside of the concentrating cylinder 5. When the defoaming arc frame 23 moves to the middle position of the concentrating cylinder 5, the driving mechanism 3 will drive the defoaming arc frame 23 and the processing filter screen to rotate, and the floating foam on the surface of the concentrating cylinder 5 will be picked up. The floating foam is blocked by the defoaming filter screen 24, and the liquid medicine picked up together with the floating foam will move to the defoaming arc frame 23 through the defoaming filter screen 24, and then be discharged back into the concentrating cylinder 5 through the discharge port of the defoaming arc frame 23, so as to promote the effective liquid medicine to return to the concentrating cylinder 5 and avoid the waste of liquid medicine. The remaining floating foam can be turned to the defoaming filter screen 24 to one side of the concentrating cylinder 5 by the handle 25 to remove the foam.

[0075] Preferably, the driving mechanism 3 includes a driving motor 31, a driving rotating rod 32, a driving slot plate 33 and a driving rotating block 34, the driving motor 31 is installed on the connecting frame 22, one end of the driving rotating rod 32 is installed on the main shaft of the driving motor 31, the driving slot plate 33 is rotatably installed on the connecting frame 22, one end of the driving rotating block 34 is rotatably installed on the connecting frame 22 and one end of the driving rotating block 34 is connected to the defoaming arc frame 23, the other end of the driving rotating rod 32 is slidably clamped on the driving slot plate 33, and the other end of the driving rotating block 34 is slidably clamped on the driving slot plate 33; the driving mechanism 3 is driven by the driving motor 31, driving the driving rotating rod 32 to rotate, the driving rotating rod 32 rotation will drive the driving slot plate 33 to rotate on the connecting frame 22, the driving slot plate 33 rotation will drive the driving rotating block 34 to rotate, so that the driving rotating block 34 will drive the defoaming arc frame 23 to rotate, and the floating foam in the concentration cylinder 5 is picked up, and the driving mechanism 3 provides driving force for the defoaming mechanism 2 to improve the defoaming efficiency.

[0076] Preferably, a foam collecting box 35 is provided on the side wall of the concentrating cylinder 5, and the foam collecting box 35 is connected to the concentrating cylinder 5. A reflux filter 36 is provided between the foam collecting box 35 and the concentrating cylinder 5; when the defoaming filter 24 is rotated to one side of the concentrating cylinder 5 by the handle 25 and the defoaming is moved to the foam collecting box 35, some medicinal liquid will be generated after the floating foam is eliminated. The medicinal liquid can flow back to the concentrating cylinder 5 through the reflux filter 36, thereby improving the utilization of medicinal resources and reducing the waste of resources.

[0077] Preferably, a method for quality control of a Chinese medicine ointment comprises the preparation of the Chinese medicine ointment, the processing of special medicinal materials, the processing of auxiliary materials and the determination of the quality of the Chinese medicine ointment, wherein the preparation of the Chinese medicine ointment comprises the following steps:

[0078] Soaking: add the medicine into the soaking box 1 for soaking, add water to exceed the medicine surface by 3-5cm, which is about 12 times the amount of water of the original medicine, and soak for more than 8 hours. During the soaking step, the quality of the soaking of the medicine is controlled;

[0079] Decoction: add decoction mechanism 6, heat to boiling over high heat, then change to low heat, keep boiling, decoct for 2 hours, sieve out the filtrate with a 60-80 mesh sieve after decoction, continue to add 8 times the volume of the original medicinal material for second decoction, decoct for 90 minutes, sieve out the filtrate with a 60-80 mesh sieve after decoction, continue to add 6 times the volume of the original medicinal material for third decoction, the third decoction is 1 hour, combine the decoction after decoction, and let it stand for precipitation;

[0080] Sedimentation: The decoction is filtered through a 60-80 mesh screen and added to a sedimentation tank 9 for static sedimentation. The sedimentation time is 8-12 hours, so that the fine particles of drug residue and impurities in the drug solution can be fully removed, so that the paste has a delicate taste;

[0081] Filtration: The precipitated liquid is filtered using a 200-mesh stainless steel filter screen 4;

[0082] Concentration: put the liquid medicine filtered through the 200-mesh stainless steel filter screen 4 into the concentration cylinder 5 for heating, and remove the floating foam by the defoaming mechanism 2 at any time, until the liquid medicine turns into a thick state, and use bamboo strips to pick up the line and let it flow down, so as to obtain the "clear paste", the density of which is 1.25-1.27;

[0083] Collecting the paste: Heat the clear paste with a slow fire, stirring constantly, add the pre-treated glue, sugar and other auxiliary materials into the clear paste of the paste collecting mechanism 7, and finally add the fine precious medicine juice. When heated, it will form a honeycomb-shaped "overturning bucket cloud". At this time, the paste (test sample) is about to be completed. It should be stirred frequently. Lift the stirring rod to see that the paste (test sample) is at a right angle of 90°. The paste (test sample) drips downward into a triangle or the paste (test sample) is clamped between the index finger and the thumb. A filament of about 2 cm can be pulled out, or a drop of the paste (test sample) is dropped into cold water. The state of beads is checked with the naked eye. At this time, the paste (test sample) is completed, and it is put into a container and cooled;

[0084] Drying the paste: The indoor environment for drying the paste needs to be disinfected with ultraviolet light for 1 hour, the temperature should be controlled below 20°C, and the relative humidity should be controlled at 45% to 75%. The container containing the paste (test sample) needs to be wiped and disinfected with 75% alcohol and kept dry. After the paste (test sample) is completely cooled, the lid containing the paste (test sample) should be closed;

[0085] The special medicinal materials include fresh dendrobium officinale, yam, lotus seeds, walnut meat, black sesame, ginseng and saffron, etc. The special medicinal materials processing method is as follows:

[0086] Fresh Dendrobium candidum: squeeze the juice, add the concentrated juice to the paste, and decoct the residue with other medicines;

[0087] Chinese yam and lotus seeds: stir-fry over low heat until the surface of the medicine turns slightly brown, turn off the heat, take out and put it at room temperature of 25℃, let it cool down and crush or mash it into a paste, add it to the paste liquid and cook together;

[0088] Walnut meat: Remove the skin and stir-fry over low heat until fragrant, or bake in an oven until the surface turns light brown and has an aroma. Sieve and let cool, then grind into coarse powder and pass through a 20-mesh sieve. When collecting the paste, add it to the paste liquid and cook for about 0.5h;

[0089] Black sesame: remove impurities from the herbs, stir-fry over low heat until there is a popping sound and the aroma escapes, take out and let cool, grind into coarse powder, add to the paste liquid and cook for 0.5h;

[0090] Ginseng and saffron: These are precious herbs and should be decocted separately. The resulting juice should be added to other creams in the concentration step for concentration. If necessary, add the original powder of the herbs. Dry the herbs in an oven at 60°C for 60 minutes, crush them, and sieve them through a 200-mesh stainless steel sieve. Add them to the cream in the cream collection step.

[0091] The processing method of the auxiliary materials is as follows:

[0092] Honey: After the honey is heated to boiling, filter it through an 80-mesh stainless steel sieve while it is hot, and then heat it until light yellow, shiny, and evenly bubbling bubbles appear. It is sticky when you rub it with your hands, and no white threads appear when you separate two fingers. At this time, the water content of the honey is 14%-16%, and the relative density is about 1.37;

[0093] Rock sugar and granulated sugar: add 1 times the amount of water to dissolve them, heat and refine until the sugar liquid is golden and shiny;

[0094] Brown sugar: Brown sugar contains more impurities, so generally add twice the amount of water as that of brown sugar, heat it to a boil, let it stand, remove the precipitate and set aside;

[0095] Maltose: After heating to boiling, the sugar liquid is golden yellow with evenly bubbling fine bubbles and has the unique caramel aroma of maltose;

[0096] Other flavoring agents: such as xylitol, chaste sugar, sodium cyclamate, etc., can be dissolved in water or precipitated liquid medicine at a ratio of 1:1, and then added to concentrate;

[0097] Glues: such as donkey-hide gelatin, deer antler glue, tortoise shell glue, etc., grind them into powder and pass through a 20-mesh stainless steel sieve, add rice wine in equal proportion to the volume of the glue, soak for about 4 hours, add them into the medicinal solution during the concentration stage, keep the medicinal solution boiling over low heat until the colloid is completely dissolved.

[0098] Preferably, the quality control method of a traditional Chinese medicine ointment is characterized in that the steps of determining the quality of the traditional Chinese medicine ointment are: relative density detection of the traditional Chinese medicine ointment, water content detection of the traditional Chinese medicine ointment and dynamic viscosity detection of the traditional Chinese medicine ointment;

[0099] The relative density detection method of the Chinese medicine ointment is as follows:

[0100] S1: Take an appropriate amount of the test sample, weigh it accurately, add twice the volume of water to the test sample, weigh it accurately, mix well, and use it as the test sample solution;

[0101] S2: Determine using the pycnometer method. Take a clean, dry and accurately weighed pycnometer, fill it with the test sample (the temperature should be below 20°C), install a thermometer (there should be no bubbles in the bottle), place it in a 20°C water bath for several minutes to make the temperature of the contents reach 20°C, remove the liquid overflowing the side tube with filter paper, immediately cover it, then take the pycnometer out of the water bath, wipe the outside of the pycnometer with filter paper, accurately weigh it, subtract the weight of the pycnometer, and after obtaining the weight of the test sample, pour out the test sample, wash the pycnometer, fill it with freshly boiled cold water, and then measure the weight of water at the same temperature according to the above method, and calculate according to the following formula;

[0102]

[0103] Where W1 is the weight of the test solution in the pycnometer, in g; W2 is the weight of the water in the pycnometer, in g.

[0104] The water content detection method of the traditional Chinese medicine ointment is to use the moisture determination method-drying method to determine: take 2-5g of the test sample, spread it flat in a flat weighing bottle that has been dried to constant weight, with a thickness of no more than 5mm, accurately weigh it, open the bottle cap and dry it at 100-105°C for 5 hours, cover the bottle cap, move it to a dryer, let it cool for 30 minutes, accurately weigh it, and then dry it at the above temperature for 1 hour, let it cool, and weigh it until the difference between two consecutive weighings does not exceed 5mg. According to the lost weight, calculate the water content (%) in the test sample;

[0105] The dynamic viscosity detection method of the Chinese medicine ointment is as follows:

[0106] Step 1: Take samples first, and test the paste (test product) when it is about to come out of the pot (95℃);

[0107] Step 2: Use a rotational viscometer to measure the dynamic viscosity. Select a suitable rotor (rotor No. 2) and immerse it in the test solution. Make the rotor rotate at a certain speed (12 r / min -1 ) rotates and the dynamic viscosity is read directly in a rotational viscometer.

[0108] Preferably, the bottom of the food may become mushy during the decocting step. To address this problem, the following measures may be taken:

[0109] (1) When preparing paste prescriptions, put the drugs with particularly high viscosity or high sugar content, such as Rehmannia glutinosa, Polygonatum sibiricum, Cistanche deserticola, and Asparagus cochinchinensis, separately and add them to the top layer of the decoction container last during soaking to prevent them from sticking to the bottom of the pot and producing a burnt smell.

[0110] (2) Stir frequently during the decoction process to speed up heat circulation, closely observe the changes in the decoction liquid and the smell of the liquid, and control the heat appropriately. Especially when the liquid is slightly boiling, stir it immediately to the bottom of the pot. At this time, stir faster, otherwise the liquid will easily overflow from the pot when it boils;

[0111] Treatment of late-added medicines in the prescription: Considering that traditional decoction and concentration time is too long, the Chinese medicinal materials that need to be added later in the prescription, such as cinnamon, amomum villosum, white cardamom, mint and other aromatic and volatile medicines, are put into disposable non-woven decoction bags and added to the concentrated solution 15 minutes before the end of the concentration process. After decoction, take out the bags to preserve the effective ingredients of the Chinese medicinal materials to the greatest extent.

[0112] Preferably, due to the differences in origin, planting environment, and harvesting methods of Chinese medicinal materials, the contents of active ingredients in the extracts of different batches may vary greatly. In the soaking step, the quality control method for the extraction process of the medicinal materials comprises the following steps:

[0113] S3: Take 1kg of medicinal materials, crush them, put them into the extraction tank, add 3-6 times the amount of water as the medicinal materials and start extraction;

[0114] S4: stirring for 10-20 minutes at extraction times of 8 hours, 10 hours, 12 hours, 14 hours, 16 hours, 18 hours, 20 hours, 22 hours, and 24 hours, respectively;

[0115] S5: taking each sterol compound of the medicinal material as the detection index, taking the end point content value of each medicinal material extraction as the target value B;

[0116] S6: using a near infrared chromatograph to take samples for testing after each stirring to detect the content of each sterol compound in the extract;

[0117] S7: repeat S3, S4, and S6 multiple times, and collect near-infrared spectra;

[0118] S8: When the contents of the sterol compounds detected in S6 all reach the extraction endpoint target value, it is determined that the soaking endpoint is reached.

[0119] Preferably, in step S6, the method for detecting the content of each sterol compound in the extract is as follows:

[0120] The index data detected in step S6 for 16 hours is set as A, in mg / ml; assuming that the detection data of each sterol compound for 16 hours are A1, A2, A3, A4, A5, etc., and taking one sterol compound as an example, the data of multiple batches of detection are assumed to be A1a, A1b, A1c, A1d, A1e, A1f, etc., and then according to the difference between the detected A and B, the stirring time of 16 hours is determined, and the dissolution of the index component is promoted so that the extraction end point is reached at 18 hours;

[0121] Calculate the C value of the index, C = (BA) / B × 100%, and select the effective component with the largest C value; if BA ≤ 0, there is no need to increase the stirring time, and the increased stirring time T = e^(a·lnC+b)+c, where T is in minutes, and a, b, c are constants;

[0122] Repeat the experiment 5 times, compare the values ​​in step S6 with the index components at the extraction endpoint, obtain the C1 and C2 values ​​before and after control for each batch, and then compare C1 and C2;

[0123]

[0124]

[0125]

[0126] It can be seen that, compared with the traditional method, after adopting the control method of the present invention, the difference between batches is significantly reduced, and the quality of the extract batches is significantly improved.

[0127] The present invention only provides monitoring of the finished medicines for the prior art, and does not perform quality control in the manufacturing process, and cannot improve the yield rate of the products. The present invention processes different medicinal materials and auxiliary materials in different ways, avoids quality problems of the quality of Chinese medicine ointment during the processing, effectively controls the quality of the finished products in production and improves its quality level; secondly, the relative density, water content and dynamic viscosity of the Chinese medicine ointment are detected, and the above three related indicators of the prepared Chinese medicine ointment are accurately measured, and the quality control standard of the Chinese medicine ointment is established accordingly, so as to help effectively control the quality of the finished products in production, ensure the controllable production process, ensure the safety of clinical use, and provide reliable guarantee for the stable and accurate efficacy of the product; provide a method for solving the problem of easy to paste the bottom of decoction, avoid quality problems of the quality of Chinese medicine ointment during the processing, and improve the quality rate of the finished products in production; at the same time, provide a quality control method in the process of medicinal material soaking, improve the yield rate of Chinese medicine ointment, and save medicinal material resources.

[0128] The above description is only an embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent substitution, improvement, etc. made within the spirit and principle of the present invention should be included in the scope of the claims of the present invention.

Claims

1. A quality control device for Chinese medicine ointment, characterized in that: The invention comprises a soaking box (1), a decoction mechanism (6), a sedimentation tank (9), a stainless steel filter screen (4), a concentration cylinder (5), a foam removal mechanism (2) and a paste collection mechanism (7), wherein the decoction mechanism (6) is installed on the side of the soaking box (1), the sedimentation tank (9) is installed on the side of the decoction mechanism (6), the stainless steel filter screen (4) is installed in the sedimentation tank (9), the concentration cylinder (5) is installed on the side of the stainless steel filter screen (4) and is connected to the stainless steel filter screen (4), and a curved plate (8) is provided in the concentration cylinder (5). The defoaming mechanism (2) is installed in the concentrating cylinder (5), the cream collecting mechanism (7) is installed beside the concentrating cylinder (5) and is connected to the concentrating cylinder (5), the defoaming mechanism (2) comprises a screw slide (21), a connecting frame (22), a driving mechanism (3), a defoaming arc frame (23), a defoaming filter (24) and a handle (25), the screw slide (21) is installed on the concentrating cylinder (5), the connecting frame (22) is installed on the slide of the screw slide (21), and the driving mechanism (3) is rotatably installed on the connecting frame (2 2), the defoaming arc frame (23) is installed on the driving mechanism (3), the defoaming arc frame (23) and the concentration cylinder (5) are both slidably matched and rotationally matched, one end of the defoaming filter (24) is hinged on the defoaming arc frame (23), the handle (25) is installed on the other end of the defoaming filter (24), the defoaming arc frame (23) is provided with a liquid discharge port, the driving mechanism (3) comprises a driving motor (31), a driving rotating rod (32), a driving slot plate (33) and a driving rotating block (34), the driving motor (31 ) is mounted on the connecting frame (22), one end of the driving rotating rod (32) is mounted on the main shaft of the driving motor (31), the driving slot plate (33) is rotatably mounted on the connecting frame (22), one end of the driving rotating block (34) is rotatably mounted on the connecting frame (22) and one end of the driving rotating block (34) is connected to the defoaming arc frame (23), the other end of the driving rotating rod (32) is slidably clamped on the driving slot plate (33), and the other end of the driving rotating block (34) is slidably clamped on the driving slot plate (33).

2. The quality control device for a Chinese medicine ointment according to claim 1, characterized in that: A foam collecting box (35) is provided on the side wall of the concentrating cylinder (5), the foam collecting box (35) is connected to the concentrating cylinder (5), and a reflux filter (36) is provided between the foam collecting box (35) and the concentrating cylinder (5).

3. A control method for a quality control device for a traditional Chinese medicine ointment as claimed in claim 1, characterized in that: The method includes the preparation of Chinese medicine ointment, the processing of special medicinal materials, the processing of auxiliary materials and the determination of the quality of Chinese medicine ointment. The preparation of Chinese medicine ointment includes the following steps: Soaking: adding the medicinal materials to the soaking box (1) for soaking, adding water to a depth of 3-5 cm above the medicinal surface, 12 times the amount of water of the original medicinal materials, and soaking for more than 8 hours. During the soaking step, the quality of the medicinal materials is controlled; Decoction: add the decoction mechanism (6), heat to boiling over high heat, then change to low heat, keep boiling, decoct for 2 hours, filter out the filtrate with a 60-80 mesh sieve after decoction, continue to add 8 times the volume of the original medicinal material for second decoction, decoct for 90 minutes, after decoction is completed, filter out the filtrate with a 60-80 mesh sieve, continue to add 6 times the volume of the original medicinal material for third decoction, the third decoction lasts for 1 hour, combine the decoction after decoction, and let it stand for precipitation; Sedimentation: The decoction is filtered through an 80-mesh screen and added to a sedimentation tank (9) for static sedimentation. The sedimentation time is 8 to 12 hours, so that the fine particles of drug residue and impurities in the drug solution are fully removed, and the paste has a delicate taste; Filtration: The precipitated drug solution is filtered using a 200-mesh stainless steel filter screen (4); Concentration: The liquid medicine filtered through a 200-mesh stainless steel filter screen (4) is placed in a concentration cylinder (5) for heating, and the floating foam is removed at any time using a defoaming mechanism (2) until the liquid medicine becomes thick and is picked up with a bamboo stick to form a line and flow downward to obtain a "clear paste" having a density of 1.25 to 1.27; Collecting the paste: Heat the clear paste with a slow fire, stirring constantly, add the pre-treated auxiliary materials into the clear paste of the paste collecting mechanism (7), and finally add the fine precious medicine juice. When heated, it will form a honeycomb-like "overturning bucket cloud". At this time, the paste is about to be completed. It should be stirred frequently. Lift the stirring rod to see that the paste is at a right angle of 90°. The paste drips downward to form a triangle or the paste is clamped between the index finger and the thumb. A 2cm thin thread can be pulled out or a drop of the paste is dropped into cold water. The state of beads is checked with the naked eye. At this time, the paste is completed. Put it into a container and cool it; Drying the paste: The indoor environment for drying the paste needs to be disinfected with ultraviolet light for 1 hour, the temperature should be controlled below 20°C, and the relative humidity should be controlled at 45% to 75%. The container containing the paste needs to be wiped and disinfected with 75% alcohol and kept dry. After the paste is completely cooled, the lid of the paste should be covered; The special medicinal material processing method is as follows: Fresh Dendrobium candidum: squeeze the juice, add the concentrated juice to the paste, and decoct the residue with other medicines; Chinese yam and lotus seeds: stir-fry over low heat until the surface of the medicine turns slightly brown, turn off the heat, take out and put it at room temperature of 25℃, let it cool down and crush or mash it into a paste, add it to the paste liquid and cook together; Walnut meat: Remove the skin and stir-fry over low heat until fragrant, or bake in an oven until the surface turns light brown and has an aroma. Sieve and let cool, then grind into coarse powder and pass through a 20-mesh sieve. When collecting the paste, add it to the paste liquid and cook for 0.5h; Black sesame: remove impurities from the herbs, stir-fry over low heat until there is a popping sound and the aroma escapes, take out and let cool, grind into coarse powder, add to the paste liquid and cook for 0.5h; Ginseng and saffron: These are precious herbs and should be decocted separately. The resulting juice should be added to other creams in the concentration step for concentration. If necessary, add the original powder of the herbs. Dry the herbs in an oven at 60°C for 60 minutes, crush them, and sieve them through a 200-mesh stainless steel sieve. Add them to the cream in the cream collection step. The processing method of the auxiliary materials is as follows: Honey: After the honey is heated to boiling, filter it through an 80-mesh stainless steel sieve while it is hot, and then heat it until light yellow, shiny, and evenly bubbling bubbles appear. It is sticky when you rub it with your hands, and no white threads appear when you separate two fingers. At this time, the water content of the honey is 14%-16%, and the relative density is 1.37; Rock sugar and granulated sugar: add 1 times the amount of water to dissolve them, heat and refine until the sugar liquid is golden and shiny; Brown sugar: Brown sugar contains more impurities, so generally add twice the amount of water as that of brown sugar, heat it to a boil, let it stand, remove the precipitate and set aside; Maltose: After heating to boiling, the sugar liquid is golden yellow with evenly bubbling fine bubbles and has the unique caramel aroma of maltose; Other flavoring agents can be dissolved in water or precipitated drug solution at a ratio of 1:1 and then added to concentrate; Glue: After crushing, pass through a 20-mesh stainless steel sieve, add yellow wine in equal proportion to the volume of the glue and soak for 4 hours. Put it into the liquid medicine during the concentration stage, keep the liquid medicine boiling over low heat until the colloid is completely dissolved. Test the relative density of the Chinese medicine ointment, the water content of the Chinese medicine ointment, and the dynamic viscosity of the Chinese medicine ointment; The relative density detection method of the Chinese medicine ointment is as follows: S1: Take an appropriate amount of the test sample, weigh it accurately, add twice the volume of water to the test sample, weigh it accurately, mix well, and use it as the test sample solution; S2: Determine using the pycnometer method. Take a clean, dry and accurately weighed pycnometer, fill it with the sample, install a thermometer, and place it in a 20°C water bath for several minutes to make the temperature of the contents reach 20°C. Use filter paper to remove the liquid overflowing the side tube, immediately cover it, and then take the pycnometer out of the water bath, wipe the outside of the pycnometer clean with filter paper, accurately weigh it, subtract the weight of the pycnometer, and after obtaining the weight of the sample, pour out the sample, wash the pycnometer, fill it with freshly boiled cold water, and then measure the weight of water at the same temperature according to the above method. Calculate according to the following formula to get the result; Where W 1 is the weight of the test solution in the pycnometer, in g; W 2 is the weight of the water in the pycnometer, in g. The water content detection method of the traditional Chinese medicine ointment is to use the moisture determination method-drying method to determine: take 2-5g of the test sample, spread it flat in a flat weighing bottle that has been dried to constant weight, with a thickness of no more than 5mm, accurately weigh it, open the bottle cap and dry it at 100-105°C for 5 hours, cover the bottle cap, move it to a dryer, cool it for 30 minutes, accurately weigh it, and then dry it at 100-105°C for 1 hour, cool it, and weigh it until the difference between two consecutive weighings does not exceed 5mg, and calculate the water content in the test sample based on the lost weight; The dynamic viscosity detection method of the Chinese medicine ointment is as follows: Step 1: Take a sample and test the paste when it is about to come out of the pot; Step 2: Use a rotational viscometer to measure the dynamic viscosity. Select a suitable rotor and immerse it in the test solution. Make the rotor rotate at a certain speed and read the dynamic viscosity directly in the rotational viscometer. In the decoction step, the bottom will be sticky. For the bottom sticking phenomenon, take the following measures: When preparing paste prescriptions, put the drugs with particularly high viscosity or high sugar content separately and add them to the upper layer of the decoction container last when soaking to prevent them from sticking to the bottom of the pot and producing a burnt smell. Stir frequently during the decoction process to speed up the heat circulation, closely observe the changes in the decoction liquid and the smell of the liquid, and properly control the fire. When the liquid boils slightly, stir it immediately to the bottom of the pot. At this time, stir faster, otherwise the liquid will easily overflow from the pot when it boils. Treatment of late-added medicines in the prescription: Considering that traditional decoction and concentration take too long, the Chinese medicinal materials that need to be added later in the prescription are put into disposable non-woven decoction bags, added to the concentrated solution 15 minutes before the end of the concentration process, and the bags are taken out after decoction to preserve the effective ingredients of the Chinese medicinal materials to the greatest extent.

4. The control method of a quality control device for a traditional Chinese medicine ointment according to claim 3, characterized in that: In the soaking step, the soaking quality control method of the medicinal material comprises the following steps: S3: taking 1 kg of the medicinal material, crushing it, putting it into an extraction tank, adding 3-6 times of water of the medicinal material to start extraction; S4: stirring for 10-20 minutes at extraction times of 8 hours, 10 hours, 12 hours, 14 hours, 16 hours, 18 hours, 20 hours, 22 hours, and 24 hours, respectively; S5: taking each sterol compound of the medicinal material as the detection index, taking the end point content value of each medicinal material extraction as the target value B; S6: using a near infrared chromatograph to take samples for testing after each stirring to detect the content of each sterol compound in the extract; S7: repeat S3, S4, and S6 multiple times, and collect near-infrared spectra; S8: When the contents of the sterol compounds detected in S6 all reach the extraction endpoint target value, it is determined that the soaking endpoint is reached.

5. The control method of a quality control device for a traditional Chinese medicine ointment according to claim 4, characterized in that: In step S6, the method for detecting the content of each sterol compound in the extract is as follows: Step 1: Set the index data detected in step S6 for 16 hours as A, in mg / ml; assume that the detection data of each steroid compound for 16 hours are A1, A2, A3, A4, A5..., and take one steroid compound as an example, the data of multiple batches of detection are assumed to be A1a, A1b, A1c, A1d, A1e, A1f...; Step 2: Then, according to the difference between A and B detected, the stirring time is determined to be 16 hours, and the dissolution of the index component is promoted so that the extraction end point is reached at 18 hours; Step 3: Calculate the C value of the index, C = (BA) / B × 100%, and select the effective component with the largest C value; if BA ≤ 0, there is no need to increase the stirring time, and the increased stirring time T = e^(a·lnC+b)+c, where T is in minutes, and a, b, c are constants; Step 4: Repeat the experiment 5 times, compare the values ​​in step S6 with the index components at the extraction endpoint, obtain the C1 and C2 values ​​before and after control for each batch, and then compare C1 and C2.

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