Biological detection cartridges and medical detection systems

By designing a simplified structure of biological detection card boxes, using a sliding chip and connecting pipe to achieve a flow channel connection, solving the problem of complexity and cost of traditional card box structures, and achieved higher qualification rates and lower costs.

CN115389751BActive Publication Date: 2025-01-28GUANGZHOU WONDFO BIOTECH
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Patent Information

Application Number
CN202110566079.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-05-24
Publication Date
2025-01-28
Estimated Expiration
2041-05-24

AI Technical Summary

Technical Problem

The traditional biological detection card box has a complex structure and high processing accuracy requirements, resulting in high defect rate and high cost.

Method used

Design a biological detection card box that includes a branch, card box, chip and connecting tube. The chip can be pulled out and pushed back. The connection of the runner through the first and second connecting pipes can be simplified and the processing accuracy requirements are reduced. Essence

Benefits of technology

Simplified product structure, reduced the requirements for processing accuracy, improved the product qualification rate, and reduced costs.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to a biological detection cartridge and a medical detection system. The biological detection cartridge comprises a support, a cartridge body, a chip, a first connecting tube and a second connecting tube. The support is provided with a first through hole. The cartridge body is provided with a second through hole corresponding to the position of the first through hole. The cartridge body is mounted on the top surface of the support. The cartridge body is also provided with a pretreatment chamber and a first flow channel connected to the pretreatment chamber. The chip is slidably arranged on the bottom surface of the support. The chip is provided with an analysis and processing chamber and a second flow channel connected to the analysis and processing chamber. In the process of the driving device pulling the chip outward or pushing the chip back to the support, the second connecting tube can bend and deform freely and adaptively, so that it can not only satisfy the chip to slide outward and push it back to the support, but also ensure the unobstructed second connecting tube, so that the liquid in the first flow channel can smoothly enter the second flow channel and the analysis and processing chamber through the first connecting tube and the second connecting tube.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a biological detection cartridge and a medical detection system. Background Art

[0002] Traditionally, some disposable biological detection cartridges with a relatively high degree of integration usually require segmented processing and analysis of liquid samples or gaseous samples. For example, before the biological sample is detected and analyzed, the sample needs to be pre-treated in the pre-treatment chamber by heating, incubation, mixing, purification, adding components and filtering. After the pre-treatment, the mixed sample is subjected to optical analysis or other analysis and processing. In general, optical analysis or other analysis and processing have special requirements for the sample placement chamber, or because of the size limit of the cartridge, the sample in the fluid state needs to be transferred from the pre-treatment chamber to another suitable analysis and processing chamber. Among them, the pre-treatment chamber and the analysis and processing chamber are respectively arranged in two different components. In order to realize the transfer of the sample in the fluid state between the chambers of the two different components, the pressure contact between two structural parts (such as a flexible part and a hard part) is usually used to realize the sealing of the docking channel between the different components. In this way, the structure is complex, the processing or molding accuracy of the relevant seals is extremely high, the defective rate of the biological detection cartridge is very high, and the cost is high. Summary of the invention

[0003] Based on this, it is necessary to overcome the defects of the prior art and provide a biological detection card box and a medical detection system, which can simplify the product structure, reduce the requirements for product processing accuracy, improve the product qualification rate, and have a lower cost.

[0004] The technical scheme is as follows: a biological detection cartridge, the biological detection cartridge comprising: a support, a cartridge body, the support being provided with a first through hole, the cartridge body being provided with a second through hole corresponding to the position of the first through hole, the cartridge body being mounted on the top surface of the support, the cartridge body being further provided with a pretreatment chamber and a first flow channel communicating with the pretreatment chamber; a chip, a first connecting tube and a second connecting tube, the chip being slidably arranged on the bottom surface of the support, the chip being provided with an analysis and processing chamber and a second flow channel communicating with the analysis and processing chamber, the first connecting tube being penetrated through the first through hole and the second through hole, one end of the first connecting tube being connected to the first flow channel, the other end of the first connecting tube being connected to one end of the second connecting tube, the second connecting tube being a flexible tube movably and curvedly arranged between the chip and the support, the other end of the second connecting tube being connected to the second flow channel.

[0005] In the above-mentioned biological detection cartridge, the chip can be slid outward from the support under the push-pull driving action of the external driving device on the chip. After the chip is pulled out, a series of analysis and processing operations can be carried out on the liquid in the analysis and processing chamber of the chip through the external detection device; after the analysis and processing operations are completed, the chip can also be slidably pushed back to the support to avoid the chip from being exposed and damaged. Among them, since the second flow channel of the chip and the first flow channel of the cartridge body are connected through the first connecting tube and the second connecting tube, and the second connecting tube is a flexible tube that is movably and curvedly arranged between the chip and the support, in the process of the driving device pulling the chip outward or pushing the chip back to the support, the second connecting tube can be freely bent and deformed accordingly, which not only satisfies the chip to slide outward and push it back to the support, but also ensures the smoothness of the second connecting tube, so that the liquid in the first flow channel can smoothly enter the second flow channel and the analysis and processing chamber through the first connecting tube and the second connecting tube.

[0006] In one embodiment, a first recess is provided on the bottom surface of the support, and the shape of the first recess is adapted to the shape of the chip; a first movable opening is provided on the side wall of the first recess for the chip to slide outward; and a docking portion is provided on the chip, and the docking portion extends out of the first recess through the first movable opening.

[0007] In one embodiment, a first bump is provided on the bottom surface of the support, and a second bump is provided on the chip, and the first bump and / or the second bump are elastic bumps; when the chip is located at the starting position, the first bump and the second bump are in abutment with each other to limit the movement of the chip in the direction of being pulled out.

[0008] In one embodiment, there are two first bumps, and there are two second bumps. The two second bumps are located on two sides of the chip, and the two second bumps are arranged in one-to-one correspondence with the two first bumps.

[0009] In one embodiment, the biological detection card box further includes a pressure cover, which is disposed on the chip and cooperates with the bottom surface of the support to form a slot, and the chip is slidably disposed in the slot.

[0010] In one embodiment, a second recess is provided on the bottom surface of the support, and the second connecting pipe is movably and curvedly disposed in the second recess.

[0011] In one embodiment, a boss is provided on the bottom wall of the second recess; the boss is located on the side of the bottom surface of the support where the chip slides outward; when the chip slides outward to the end position, the boss contacts the second connecting tube.

[0012] In one embodiment, the biological detection cartridge further comprises a first hard tube disposed between the first connecting tube and the first flow channel, the first connecting tube being connected to the first flow channel through the first hard tube; a first mounting hole is disposed on the cartridge body, and the first hard tube is fixedly mounted in the first mounting hole;

[0013] The biological detection cartridge further includes a second hard tube disposed between the second connecting tube and the second flow channel, the second connecting tube being connected to the second flow channel through the second hard tube; a second mounting hole is disposed on the chip, and the second hard tube is mounted in the second mounting hole.

[0014] In one embodiment, the biological detection card box further includes an upper cover, and the upper cover is disposed on the card box body.

[0015] A medical detection system comprises the biological detection cartridge.

[0016] In the above-mentioned medical detection system, under the push-pull driving action of the external driving device on the chip, the chip can be slid outward from the support, and after the chip is pulled out, a series of analysis and processing operations can be carried out on the liquid in the analysis and processing chamber of the chip through the external detection device; after the analysis and processing operations are completed, the chip can also be slidably pushed back to the support, which can prevent the chip from being exposed and damaged. Among them, since the second flow channel of the chip and the first flow channel of the cartridge body are connected through the first connecting tube and the second connecting tube, and the second connecting tube is a flexible tube that is movably and curvedly arranged between the chip and the support, in the process of the driving device pulling the chip outward or pushing the chip back to the support, the second connecting tube can be freely bent and deformed accordingly, which not only satisfies the chip to slide outward and push it back to the support, but also ensures the smoothness of the second connecting tube, so that the liquid in the first flow channel can smoothly enter the second flow channel and the analysis and processing chamber through the first connecting tube and the second connecting tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The drawings constituting a part of this application are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute improper limitations on the present invention.

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 A schematic diagram of the structure of a biological detection cartridge according to an embodiment of the present invention;

[0020] Figure 2 for Figure 1 A schematic diagram of the structure when the chip in the chip is pulled out;

[0021] Figure 3 This is a schematic structural diagram of a biological detection cartridge according to an embodiment of the present invention, in which a chip is located on a support and a cover is separated;

[0022] Figure 4 This is a schematic diagram of the structure of the biological detection card box with the cover and chip separated according to one embodiment of the present invention;

[0023] Figure 5 It is a schematic diagram of the structure of a biological detection cartridge according to an embodiment of the present invention when the chip is pulled outward and the pressure cover is separated;

[0024] Figure 6 This is a schematic diagram of the exploded structure of a biological detection cartridge according to an embodiment of the present invention;

[0025] Figure 7 It is a structural schematic diagram of a card box body and a chip of a biological detection card box according to an embodiment of the present invention;

[0026] Figure 8 for Figure 7 Another perspective structure diagram.

[0027] 10. Support; 11. First through hole; 12. Bottom surface; 13. Top surface; 14. First recess; 15. First movable opening; 16. First convex point; 17. Avoidance groove; 18. Second recess; 181. Boss; 182. First interval; 183. Second interval; 191. First clamping piece; 192. Second clamping hole; 20. Cartridge body; 21. Second through hole; 22. Pretreatment chamber; 23. First flow channel; 24. First clamping hole; 30. Chip; 31. Analysis and processing chamber; 32. Second flow channel; 33. Docking part; 34. Second convex point; 40. First connecting tube; 50. Second connecting tube; 60. Pressure cover; 61. Socket; 62. Second clamping piece; 71. First hard tube; 72. Second hard tube; 80. Upper cover. DETAILED DESCRIPTION

[0028] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0029] See also Figure 1 , Figure 2 , Figure 6 and Figure 7 , Figure 1 FIG. 1 is a schematic diagram showing the structure of a biological detection cartridge according to an embodiment of the present invention. Figure 2 Shows Figure 1 A schematic diagram of the structure when the chip 30 is pulled outward, Figure 6 FIG. 1 is a schematic diagram showing the exploded structure of a biological detection cartridge according to an embodiment of the present invention. Figure 7 The schematic diagram of the structure of the cartridge body 20 and the chip 30 of the biological detection cartridge according to an embodiment of the present invention is shown. A biological detection cartridge provided by an embodiment of the present invention comprises a support 10, a cartridge body 20, a chip 30, a first connecting tube 40 and a second connecting tube 50.

[0030] The support 10 is provided with a first through hole 11. The cartridge body 20 is provided with a second through hole 21 corresponding to the position of the first through hole 11. The cartridge body 20 is mounted on the top surface 13 of the support 10. The cartridge body 20 is also provided with a pre-treatment chamber 22 and a first flow channel 23 (such as Figure 7 As shown). The chip 30 is slidably disposed on the bottom surface 12 of the support 10, and an analysis and processing chamber 31 and a second flow channel 32 communicating with the analysis and processing chamber 31 are provided on the chip 30. The first connecting tube 40 is disposed through the first through hole 11 and the second through hole 21, one end of the first connecting tube 40 is connected to the first flow channel 23, and the other end of the first connecting tube 40 is connected to one end of the second connecting tube 50. The second connecting tube 50 is a flexible tube movably and curvedly disposed between the chip 30 and the support 10, and the other end of the second connecting tube 50 is connected to the second flow channel 32.

[0031] In the above-mentioned biological detection card box, under the push-pull driving action of the external driving device on the chip 30, the chip 30 can be slid outward from the support 10, and after the chip 30 is pulled out, a series of analysis and processing operations can be carried out on the liquid in the analysis and processing chamber 31 of the chip 30 through the external detection device; after the analysis and processing operations are completed, the chip 30 can also be slidably pushed back to the support 10 to prevent the chip 30 from being exposed and damaged. Among them, since the second flow channel 32 of the chip 30 and the first flow channel 23 of the card box body 20 are connected through the first connecting tube 40 and the second connecting tube 50, and the second connecting tube 50 is a flexible tube that is movably and curvedly arranged between the chip 30 and the support 10, the second connecting tube 50 can bend and deform freely and adaptively during the process of the driving device pulling the chip 30 outward or pushing the chip 30 back to the support 10. This not only satisfies the chip 30 sliding outward and pushing it back to the support 10, but also ensures the smoothness of the second connecting tube 50, so that the liquid in the first flow channel 23 can smoothly enter the second flow channel 32 and the analysis and processing chamber 31 through the first connecting tube 40 and the second connecting tube 50.

[0032] It should be noted that the number of pre-treatment chambers 22 provided on the cartridge body 20 may be more than one, and the number of first flow channels 23 may be more than one. Their specific numbers are set according to actual needs and are not limited here. In addition, the number of analysis and processing chambers 31 provided on the chip 30 may be more than one, and the number of second flow channels 32 may be more than one. Their specific numbers can be set according to actual needs and are not limited here.

[0033] It should be noted that the "first connecting tube 40" can be "a part of the second connecting tube 50", that is, the "first connecting tube 40" and "the other part of the second connecting tube 50" are integrally formed; or it can be an independent component that can be separated from the "other part of the second connecting tube 50", that is, the "first connecting tube 40" can be manufactured independently and then combined with the "other part of the second connecting tube 50" into a whole. Figure 6 As shown, in one embodiment, the “first connecting pipe 40 ” is a part of the “second connecting pipe 50 ” that is integrally formed.

[0034] See also Figure 3 and Figure 4 , Figure 3 The schematic diagram shows a structure in which the chip 30 of the biological detection cartridge according to an embodiment of the present invention is located on the support 10 and the pressure cover 60 is separated. Figure 4The schematic diagram of the structure of the bioassay cartridge of one embodiment of the present invention is shown in which the pressure cover 60 and the chip 30 are separated. In one embodiment, a first recess 14 is provided on the bottom surface 12 of the support 10, and the shape of the first recess 14 is adapted to the shape of the chip 30. The side wall of the first recess 14 is provided with a first movable opening 15 for the chip 30 to slide out. Further, the chip 30 is provided with a docking portion 33, and the docking portion 33 extends out of the first recess 14 through the first movable opening 15. Thus, on the one hand, since the chip 30 is adapted to the shape of the first recess 14, under the push-pull action of the external driving device on the chip 30, it is easy to slide the chip 30 outward along the first recess 14 through the first movable opening 15, and it is also easy to push the chip 30 back to the first recess 14 along the first recess 14, so that the operation stability of the chip 30 is better; on the other hand, when the chip 30 is located in the first recess 14, since the docking portion 33 of the chip 30 extends out of the first recess 14 through the first movable opening 15, it is convenient for the external driving device to act on the docking portion 33 of the chip 30 and pull the chip 30 outward along the first recess 14, which is more convenient. Among them, in order to facilitate docking with the driving end of the external driving device, the docking portion 33 is provided with a docking hole or a docking protrusion, etc.

[0035] See also Figures 4 to 6 , Figure 5 The schematic diagram of the structure of the bioassay cartridge according to one embodiment of the present invention when the chip 30 is pulled out and the pressure cover 60 is separated is shown. In one embodiment, the bottom surface 12 of the support 10 is provided with a first bump 16, and the chip 30 is provided with a second bump 34, and the first bump 16 and / or the second bump 34 are elastic bumps. When the chip 30 is at the starting position, the first bump 16 and the second bump 34 are in contact with each other to limit the movement of the chip 30 in the direction of being pulled out.

[0036] It should be noted that the chip 30 has a starting position (such as Figure 3 corresponding position) and the end position (such as Figure 5 Corresponding position), when the chip 30 is not pulled out from the support 10, or the chip 30 is pushed back to the support 10 under the push-pull action of the driving device, the chip 30 is located at the starting position; when the chip 30 is pulled out from the support 10 under the push-pull action of the driving device, the chip 30 is correspondingly located at the end position.

[0037] See also Figures 4 to 6When the chip 30 is located at the starting position, the first convex point 16 and the second convex point 34 are in contact with each other to limit the movement of the chip 30 in the direction of being pulled out. In general, the chip 30 will not slide out from the support 10 easily, that is, it plays a good positioning role for the chip 30, and can avoid the chip 30 from being damaged after being moved out, such as causing the second flow channel 32 or the analysis and processing chamber 31 to leak. Of course, under the push-pull action of the driving device, the chip 30 is subjected to a sufficiently large pulling force, and the elastic convex point will be deformed accordingly when subjected to the force, that is, the chip 30 can be smoothly pulled out from the support 10, and the chip 30 can also be reset to the starting position.

[0038] As an optional solution, one of the first protrusion 16 and the second protrusion 34 can be replaced by a positioning hole, and the other of the first protrusion 16 and the second protrusion 34 is correspondingly configured as an elastic protrusion that can be inserted into the positioning hole.

[0039] See also Figures 4 to 6 In one embodiment, there are two first bumps 16 and two second bumps 34, and the two second bumps 34 are located on both sides of the chip 30, and the two second bumps 34 are arranged one by one with the two first bumps 16. In this way, when the chip 30 is located at the starting position, the support 10 can play a better positioning role for the chip 30 through the two first bumps 16 respectively contacting and cooperating with the two second bumps 34 on the chip 30. Specifically, when the second bumps 34 are located on the bottom surface 12 of the support 10 and the chip 30 faces the support 10, in order to avoid the second bumps 34 and ensure that the chip 30 can be smoothly slid outward or pushed back onto the support 10 on the bottom surface 12 of the support 10, an avoidance groove 17 is provided on the bottom surface 12 of the support 10, and the second bumps 34 are arranged in the avoidance groove 17 and can move along the avoidance groove 17. Since the avoidance groove 17 only needs to avoid the second bump 34 so that the second bump 34 can move along the avoidance groove 17, the avoidance groove 17 is designed to be narrow in width and in the shape of a linear groove, so that the second bump 34 moves along the avoidance groove 17, and the avoidance groove 17 can also play a certain guiding role for the chip 30.

[0040] See also Figures 2 to 4 In one embodiment, the biological detection cartridge further includes a pressure cover 60. The pressure cover 60 is disposed on the chip 30 and cooperates with the bottom surface 12 of the support 10 to form a slot 61, and the chip 30 is slidably disposed in the slot 61. In this way, the pressure cover 60 can prevent the chip 30 from falling downward, and at the same time, protect the chip 30 when the chip 30 is located in the movable slot 61.

[0041] See also Figures 3 to 5In one embodiment, a second recess 18 is provided on the bottom surface 12 of the support 10, and the second connecting tube 50 is movably and curvedly disposed in the second recess 18. In this way, when the chip 30 moves along the bottom surface 12 of the support 10, the second connecting tube 50 can smoothly move and self-deform in the second recess 18, which not only satisfies the chip 30 to slide outward and push it back to the support 10, but also ensures the unobstructed second connecting tube 50, so that the liquid in the first flow channel 23 can smoothly enter the second flow channel 32 and the analysis and processing chamber 31 through the first connecting tube 40 and the second connecting tube 50.

[0042] See also Figures 3 to 5 In one embodiment, a boss 181 is provided on the bottom wall of the second recess 18. The boss 181 is located on the side of the bottom surface 12 of the support 10 where the chip 30 slides outward; when the chip 30 slides outward to the terminal position, the boss 181 conflicts with the second connecting tube 50. In this way, when the chip 30 slides outward to the terminal position, the boss 181 conflicts with the second connecting tube 50, thereby preventing the chip 30 from continuing to slide outward. Specifically, one side of the boss 181 also cooperates with one side of the inner wall of the recess to form a first gap 182, and the other side of the boss 181 also cooperates with the other side of the inner wall of the recess to form a second gap 183. The first gap 182 is used to adapt to one end of the second connecting tube 50. One end of the second connecting tube 50 is movably disposed in the first compartment 182 . The second compartment 183 is used to adapt to the other end of the second connecting tube 50 . The other end of the second connecting tube 50 is movably disposed in the second compartment 183 .

[0043] See also Figure 4 and Figure 5 It should be noted that when both the first recess 14 and the second recess 18 are provided on the bottom surface 12 of the support 10, the second recess 18 is provided on the bottom wall of the first recess 14, that is, it is formed by extending inwardly from a certain area of ​​the bottom wall of the first recess 14.

[0044] See also Figure 6 In one embodiment, the biological detection cartridge further includes a first hard tube 71 disposed between the first connecting tube 40 and the first flow channel 23, and the first connecting tube 40 is connected to the first flow channel 23 through the first hard tube 71. A first mounting hole is disposed on the cartridge body 20, and the first hard tube 71 is fixedly mounted in the first mounting hole.

[0045] In addition, the biological detection cartridge further includes a second hard tube 72 disposed between the second connecting tube 50 and the second flow channel 32, and the second connecting tube 50 is connected to the second flow channel 32 through the second hard tube 72. A second mounting hole is disposed on the chip 30, and the second hard tube 72 is mounted in the second mounting hole.

[0046] Specifically, the first hard tube 71 is fixedly disposed in the first mounting hole by, for example, adhesive bonding. In addition, the second hard tube 72 is fixedly disposed in the second mounting hole by, for example, adhesive bonding. In this way, the first hard tube 71 can facilitate the first connecting tube 40 to be connected to the first flow channel 23, and the first hard tube 71 is fixed in position to position the end of the first connecting tube 40. Similarly, the second hard tube 72 can facilitate the second connecting tube 50 to be connected to the second flow channel 32, and the second hard tube 72 is fixed in position to position the end of the second connecting tube 50.

[0047] See also Figures 6 to 8 , Figure 8 Shows Figure 7 Another perspective structural diagram of the first connecting tube 40. Optionally, the first connecting tube 40 can be a hard tube or a flexible tube, which is not limited here. In this embodiment, the first connecting tube 40 is a flexible tube, and is curved, so that the first connecting tube 40 is easy to connect to the first hard tube 71 and the second connecting tube 50 respectively.

[0048] See also Figure 1 and Figure 2 In one embodiment, the biological detection cartridge further includes an upper cover 80. The upper cover 80 is disposed on the cartridge body 20. Thus, after the upper cover 80 is disposed on the cartridge body 20, it protects the cartridge body 20 and can also cooperate with the cartridge body 20 to perform some pretreatment operations on the cartridge body 20. For example, a syringe can be disposed on the upper cover 80, and the external pretreatment device can provide power by driving the syringe to realize the transfer of the liquid in the pretreatment chamber 22.

[0049] See also Figure 6 Furthermore, the card box body 20 is fixed on the top surface 13 of the support 10 by, for example, clamping, and of course, it can also be installed on the support 10 in other ways. In this embodiment, the support 10 is provided with at least one first clamping member 191, and the card box body 20 is provided with at least one first clamping hole 24, and at least one first clamping member 191 is clamped and installed in at least one first clamping hole 24 in a one-to-one correspondence.

[0050] See also Figure 5 Furthermore, the pressure cover 60 is fixed to the bottom surface 12 of the support 10 by, for example, clamping, and can of course be installed on the support 10 in other ways. In this embodiment, the pressure cover 60 is provided with at least one second clamping member 62, and the support 10 is provided with at least one second clamping hole 192, and the at least one second clamping member 62 is clamped and installed in the at least one second clamping hole 192 in a one-to-one correspondence.

[0051] Further, the upper cover 80 is disposed on the card box body 20 by, for example, snapping, and of course, it can also be mounted on the card box body 20 in other ways. In this embodiment, at least one third snap-fitting member is disposed on the upper cover 80, and at least one third snap-fitting hole is disposed on the card box body 20, and at least one third snap-fitting member is snap-fitted and mounted in the at least one third snap-fitting hole in a one-to-one correspondence.

[0052] Please refer to Figure 1 and Figure 6 In one embodiment, a medical detection system includes the biological detection cartridge of any of the above embodiments.

[0053] In the above-mentioned medical detection system, under the push-pull driving action of the external driving device on the chip 30, the chip 30 can be slid outward from the support 10, and after the chip 30 is pulled out, a series of analysis and processing operations can be carried out on the liquid in the analysis and processing chamber 31 of the chip 30 through the external detection device; after the analysis and processing operation is completed, the chip 30 can also be slidably pushed back to the support 10 to prevent the chip 30 from being exposed and damaged. Among them, since the second flow channel 32 of the chip 30 and the first flow channel 23 of the card box body 20 are connected through the first connecting tube 40 and the second connecting tube 50, and the second connecting tube 50 is a flexible tube that is movably and curvedly arranged between the chip 30 and the support 10, the second connecting tube 50 can bend and deform freely and adaptively during the process of the driving device pulling the chip 30 outward or pushing the chip 30 back to the support 10. This not only satisfies the chip 30 sliding outward and pushing it back to the support 10, but also ensures the smoothness of the second connecting tube 50, so that the liquid in the first flow channel 23 can smoothly enter the second flow channel 32 and the analysis and processing chamber 31 through the first connecting tube 40 and the second connecting tube 50.

[0054] It should be noted that the "first protrusion 16" can be "a part of the support 10", that is, the "first protrusion 16" and the "other parts of the support 10" are manufactured as one piece; it can also be an independent component that can be separated from the "other parts of the support 10", that is, the "first protrusion 16" can be manufactured independently and then combined with the "other parts of the support 10" into a whole.

[0055] It should be noted that the "second bump 34" can be "a part of the chip 30", that is, the "second bump 34" and the "other parts of the chip 30" are manufactured as one piece; it can also be an independent component separable from the "other parts of the chip 30", that is, the "second bump 34" can be manufactured independently and then combined with the "other parts of the chip 30" into a whole.

[0056] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0057] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

[0058] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0059] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0060] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0061] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0062] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are for illustrative purposes only and are not intended to be the only implementation method.

Claims

1. A biological detection cartridge, characterized in that: The biological detection cartridge comprises: A support and a cartridge body, wherein the support is provided with a first through hole, the cartridge body is provided with a second through hole corresponding to the position of the first through hole, the cartridge body is mounted on the top surface of the support, and the cartridge body is further provided with a pretreatment chamber and a first flow channel communicating with the pretreatment chamber; A chip, a first connecting tube and a second connecting tube, wherein the chip is slidably disposed on the bottom surface of the support, an analysis and processing chamber and a second flow channel connected to the analysis and processing chamber are provided on the chip, the first connecting tube is penetrated through the first through hole and the second through hole, one end of the first connecting tube is connected to the first flow channel, the other end of the first connecting tube is connected to one end of the second connecting tube, the second connecting tube is a flexible tube movably and curvedly disposed between the chip and the support, the other end of the second connecting tube is connected to the second flow channel; The chip can be slid outward and pulled out and pushed back into the support, while ensuring the unobstructed state of the second connecting pipe, so that the liquid in the first flow channel can smoothly enter the second flow channel and the analysis and processing chamber through the first connecting pipe and the second connecting pipe.

2. The biological detection cartridge according to claim 1, characterized in that: A first recess is provided on the bottom surface of the support, and the shape of the first recess is adapted to the shape of the chip; a first movable opening is provided on the side wall of the first recess for the chip to slide out; and a docking portion is provided on the chip, and the docking portion extends out of the first recess through the first movable opening.

3. The biological detection cartridge according to claim 1, characterized in that: A first bump is provided on the bottom surface of the support, and a second bump is provided on the chip, and the first bump and / or the second bump are elastic bumps; when the chip is at the starting position, the first bump and the second bump are in contact with each other to limit the movement of the chip in the direction of being pulled out.

4. The biological detection cartridge according to claim 3, characterized in that: There are two first bumps and two second bumps, the two second bumps are located at two sides of the chip, and the two second bumps are arranged in one-to-one correspondence with the two first bumps.

5. The biological detection cartridge according to claim 1, characterized in that: The biological detection card box also includes a pressure cover, which is arranged on the chip and cooperates with the bottom surface of the support to form a slot, and the chip is slidably arranged in the slot.

6. The biological detection cartridge according to claim 1, characterized in that: A second recess is provided on the bottom surface of the support, and the second connecting pipe is movably and curvedly arranged in the second recess.

7. The biological detection cartridge according to claim 6, characterized in that: The bottom wall of the second recess is provided with a boss; the boss is located on the side of the bottom surface of the support where the chip slides outward; when the chip slides outward to the end position, the boss contacts the second connecting tube.

8. The biological detection cartridge according to claim 1, characterized in that: The biological detection cartridge further comprises a first hard tube disposed between the first connecting tube and the first flow channel, wherein the first connecting tube is connected to the first flow channel through the first hard tube; a first mounting hole is disposed on the cartridge body, and the first hard tube is fixedly mounted in the first mounting hole; The biological detection cartridge further includes a second hard tube disposed between the second connecting tube and the second flow channel, the second connecting tube being connected to the second flow channel through the second hard tube; a second mounting hole is disposed on the chip, and the second hard tube is mounted in the second mounting hole.

9. The biological detection cartridge according to any one of claims 1 to 8, characterized in that: The biological detection card box also includes an upper cover, and the upper cover is arranged on the card box body.

10. A medical detection system, characterized in that: The medical detection system comprises the biological detection cartridge as described in any one of claims 1 to 9.

Citation Information

Patent Citations

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