A sunscreen composition, an oil-in-water sunscreen lotion preparation, and a preparation method and application thereof

Abstract

The present invention relates to the technical field of A61K8 / 00, and specifically to a sunscreen composition, an oil-in-water sunscreen lotion preparation, and a preparation method and application thereof. A sunscreen composition, in parts by weight, is prepared from raw materials consisting of 0.1-0.5 parts of a thickener, 0.5-1.5 parts of a film former, 0.1-1 parts of an emulsifier, and 0.02-2 parts of a plant extract, wherein the plant extract includes asiaticoside. The sunscreen composition provided by the present invention and the sunscreen composition containing the sunscreen composition are suitable for use in an oil-in-water sunscreen lotion preparation, and have the characteristics of being refreshing and non-greasy, non-mud-rubbing, non-suffocating, light burden, waterproof and non-allergenic, and are suitable for use by people with oily skin and sensitive skin for sunscreen needs.

Description

Technical Field

[0001] The present invention relates to the technical field of A61K8 / 00, and in particular to a sunscreen composition, an oil-in-water sunscreen lotion preparation, and a preparation method and application thereof. Background Art

[0002] As global pollution becomes more and more serious, it has caused serious damage to the atmosphere. We can now feel that the intensity of daily ultraviolet rays is getting higher and higher, and the damage to the skin is becoming more and more serious. More and more people feel that they have sensitive skin and have higher and higher requirements for sunscreen products. However, at present, most sunscreen cosmetics such as sunscreen lotion, sunscreen cream or sunscreen spray are oil-in-water sunscreen products. Oil-in-water sunscreen products are highly greasy. In order to reduce the greasy skin feel of sunscreen products, it is generally necessary to add a higher content of alcohol or alcohol substitutes. These sunscreen products are safe for healthy skin, but sunscreen products containing more alcohol may bring irritation to sensitive skin or skin with damaged barrier, or further increase the risk of barrier damage.

[0003] In order to improve the irritation of sunscreen products on sensitive skin or skin with damaged barrier, alcohol is removed from sunscreen products. However, after the alcohol is removed, the sunscreen products generally feel heavy when used, have poor stability, and are severely rubbed white, which seriously affects their normal usage and reduces the sunscreen effect. Although pure physical sunscreen is safe, it is limited by stability, poor user experience and other issues. In order to improve its stability, most physical sunscreen products on the market use oil-in-water formulations. However, oil-in-water physical sunscreens have the disadvantages of being rubbed white, easy oil-water separation, not easy to clean, and prone to causing acne and mud for sensitive skin. In recent years, physical sunscreens and chemical sunscreens have been used in oil-in-water sunscreen products. In order to improve the stability of physical sunscreens and chemical sunscreens in oil-in-water sunscreen products, it is generally necessary to increase the amount of traditional emulsifiers and co-emulsifiers to improve the emulsification ability and consistency, thereby improving stability. However, increasing the amount of emulsifiers and co-emulsifiers and increasing the consistency of the oil-in-water system will reduce the water resistance of the oil-in-water sunscreen product, and when encountering sweat or water, it will destroy the sunscreen effect of the oil-in-water sunscreen product; and for sensitive skin, the high content of emulsifiers in the sunscreen products used is prone to bring problems such as heavy burden or irritation to the skin. The Chinese patent with patent application number CN202210409643.6 discloses an emulsifier composition, an oil-in-water composition, and its preparation method and application, which solves the technical problem that the traditional mint cream contains more methyl salicylate, menthol and camphor, which is more irritating to the skin and allergenic to the skin.

[0004] Therefore, providing a sunscreen composition for sensitive skin, especially oily skin and sensitive skin and an oil-in-water sunscreen lotion preparation containing the sunscreen composition is a major technical problem that needs to be solved at present. Summary of the invention

[0005] In order to solve the above problems, the first aspect of the present invention provides a sunscreen composition, which is prepared by raw materials consisting of 0.1-0.5 parts of a thickener, 0.5-1.5 parts of a film-former, 0.1-1 parts of an emulsifier, and 0.02-2 parts of a plant extract, wherein the plant extract includes Centella asiatica.

[0006] Furthermore, the sunscreen composition, in parts by weight, comprises raw materials including 0.4 parts of a thickener, 0.8 parts of a film former, 0.2 parts of an emulsifier, and 0.05 parts of a plant extract, wherein the plant extract includes asiaticaside.

[0007] Furthermore, the plant extract also includes madecassoside.

[0008] Preferably, the thickener includes one or more of acrylic acid (esters) / C10-30 alkyl acrylate cross-polymer, carbomer, xanthan gum, and hydroxyethyl cellulose.

[0009] Preferably, the thickener comprises acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer and xanthan gum, and the weight ratio of acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer and xanthan gum is (1-4):1.

[0010] Furthermore, the thickener is preferably acrylic acid (esters) / C10-30 alkyl alcohol acrylate cross-linked polymer and xanthan gum, and the weight ratio of acrylic acid (esters) / C10-30 alkyl alcohol acrylate cross-linked polymer and xanthan gum is 2:1.

[0011] In order to solve the problem that physical sunscreen agents are prone to flocculation in oil-in-water emulsion systems, causing oil-water separation in oil-in-water emulsion systems, the inventors creatively discovered during the experiment that by limiting the type and ratio of thickeners used in the sunscreen composition, the thickener is preferably acrylates / C10-30 alkyl acrylate cross-linked polymer and xanthan gum, and the weight ratio of the acrylates / C10-30 alkyl acrylate cross-linked polymer to the xanthan gum is (1-4):1, especially when the weight ratio of the acrylates / C10-30 alkyl acrylate cross-linked polymer to the xanthan gum is 2:1, the use of physical sunscreen agents and chemical sunscreen agents in combination can solve the problem that physical sunscreen agents are prone to flocculation in oil-in-water emulsion systems, avoid the problem that oil-water separation occurs in oil-in-water sunscreen lotion preparations after the use of physical sunscreen agents, and further avoid the problem that oil-water separation occurs in the final product; when the amount of xanthan gum used exceeds the amount of acrylates / C10-30 When cross-linking polymers with alkyl acrylates, the stability of the sunscreen in the system will be reduced, resulting in flocculation or slight oil-water separation problems.

[0012] Preferably, the film former includes one or more of VP / hexadecene copolymer, VP / eicosene copolymer, octyl pyrrolidone, and trimethylsiloxysilicate.

[0013] Furthermore, the film-forming agent is preferably VP / eicosene copolymer.

[0014] Preferably, the emulsifier includes one or more of ceteareth-30, beheneth-25, sorbitan olivate, laureth-23, and glyceryl stearate.

[0015] Furthermore, the emulsifier is preferably beheneth-25.

[0016] In order to reduce the amount of emulsifier used in the water-in-oil emulsion system and improve the safety and stability of the product, especially for people with sensitive skin, the inventors creatively discovered in experiments that by using thickeners, film formers, emulsifiers, and plant extracts in combination, especially when using 0.1-0.5 parts of thickeners, 0.5-1.5 parts of film formers, 0.1-1 parts of emulsifiers, and 0.02-2 parts of plant extracts, the thickener is preferably acrylic acid (ester) / C10-30 The invention relates to a cross-linked polymer of alkyl acrylate and xanthan gum, wherein the film-forming agent is preferably VP / eicosene copolymer, and the plant extracts include asiaticoside and hydroxy-madecassoside. When used in combination, it can not only improve the stability of physical sunscreens and chemical sunscreens in an oil-in-water emulsion system, but also avoid the problem of system flocculation caused by the physical sunscreen in the oil-in-water emulsion system. In particular, the plant extracts have a synergistic and obvious synergistic effect with the thickener, film-forming agent and emulsifier. In particular, compared with the traditional sunscreen emulsion system, a small amount of emulsifier is used in the present application to obtain an oil-in-water emulsion system with excellent stability. The possible reason is that by limiting the types and proportions of the thickener, film-forming agent, emulsifier and plant extract, in particular, by using acrylic acid (ester) / C10-30 After the cross-linked polymer of alkyl acrylate, xanthan gum, and VP / eicosene copolymer are combined, a stable spatial network structure can be formed, and a stable water-in-oil emulsion system can be obtained by using a small amount of emulsifier and plant extract; and the raw materials of the sunscreen composition used in the present application are safe and non-irritating, and have good application prospects.

[0017] A second aspect of the present invention provides an oil-in-water sunscreen lotion preparation, comprising a sunscreen composition.

[0018] Furthermore, the oil-in-water sunscreen lotion preparation includes a sunscreen composition, a sunscreen agent, an emollient, a moisturizer, a preservative, a chelating agent, a pH regulator, a skin protectant, and water.

[0019] Preferably, the preparation raw materials include, by mass percentage, 0.75-8.7% of sunscreen composition, 10.0-20.0% of sunscreen agent, 5.0-15.0% of emollient, 3.0-8.0% of moisturizer, 0.1-3.2% of preservative, 0.05-0.2% of chelating agent, 0.01-0.2% of pH adjuster, 1.0-8.0% of skin protectant, and the remainder of water; the sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the moisturizer includes moisturizer a and moisturizer b.

[0020] Preferably, the moisturizing agent is selected from one or both of butylene glycol and 1,2-pentanediol.

[0021] Preferably, the moisturizing agent a is preferably butylene glycol, and the moisturizing agent b is preferably 1,2-pentanediol.

[0022] Preferably, the skin protectant includes skin protectant a and skin protectant b.

[0023] Preferably, the weight ratio of the skin protectant a to the skin protectant b is (4-20):1.

[0024] Preferably, the skin protectant is selected from one or more of aluminum starch octenylsuccinate, carnosine, bisabolol, MAGNOLIA BIONDII flower extract, frankincense resin extract, and LOTUS CORNICULATUS seed extract.

[0025] Preferably, the skin protective agent a is aluminum starch octenylsuccinate.

[0026] Furthermore, the skin protectant b comprises one or both of MAGNOLIA BIONDII flower extract and LOTUS CORNICULATUS seed extract.

[0027] Furthermore, the skin protectant b comprises one or both of a composition consisting of a MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination and a composition consisting of a LOTUS CORNICULATUS seed extract / 1,3-propylene glycol / water combination.

[0028] Preferably, the weight ratio of the composition of Magnolia biondii flower extract / 1,3-propylene glycol and the composition of Lotus corniculatus seed extract / 1,3-propylene glycol / water is 1:1.

[0029] Preferably, the water is purified water.

[0030] Preferably, the pH adjuster includes one or both of sodium citrate and arginine.

[0031] Furthermore, the pH regulator is preferably sodium citrate combined with arginine, and the weight ratio of the sodium citrate to arginine is 1:(1-3).

[0032] Furthermore, the weight ratio of the sodium citrate to arginine is 1:2.

[0033] Preferably, the preservative is selected from one or more of p-hydroxyacetophenone, caprylhydroxamic acid, and glyceryl caprylate.

[0034] Furthermore, the preservative is preferably p-hydroxyacetophenone.

[0035] Preferably, the chelating agent is disodium EDTA.

[0036] Preferably, the emollient is selected from one or more of dibutyl adipate, propylheptyl octanoate, and isotridecanol isononanoate.

[0037] Preferably, the sunscreen includes chemical sunscreen and physical sunscreen.

[0038] Furthermore, the physical sunscreen is preferably titanium dioxide.

[0039] Furthermore, the physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0040] Furthermore, the chemical sunscreen is selected from one or more of ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and methylene bis-benzotriazolyl tetramethylbutylphenol.

[0041] Furthermore, the chemical sunscreen includes ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0042] In order to improve the stability of oil-in-water sunscreen lotion preparations, the inventors creatively discovered in experiments that by adding physical and chemical sunscreens and chemical sunscreens for combined use on the basis of defining the raw materials and amounts of thickeners, film formers, emulsifiers and plant extracts, and also adding emollients, moisturizers, preservatives, chelating agents, pH regulators and skin protectants for combined use, the problem of instability and oil-water separation in oil-in-water sunscreen products after the combination of physical sunscreens and chemical sunscreens in the industry can be solved, and the problem of improving the stability of oil-in-water sunscreen lotion preparations by increasing the thickener content to increase the product consistency can also be solved; by adopting the sunscreen composition, sunscreen, emollient, moisturizer, preservative, chelating agent, pH regulator, skin protectant and water as defined in the present application, the fluidity of the oil-in-water sunscreen lotion preparation can be improved, and the preparation has the effects of being easy to apply, light in burden and good in stability, and is especially suitable for use by people with sensitive skin, and particularly suitable for daily sun protection use by people with oily sensitive skin.

[0043] Furthermore, the manufacturers and models of the preferred raw materials are shown in Table 1.

[0044] Table 1

[0045]

[0046] The third aspect of the present invention provides a method for preparing an oil-in-water sunscreen lotion preparation, comprising the following steps:

[0047] S1: pre-moistening the thickener in the sunscreen composition with moisturizer a until uniform, then adding it into water and stirring for 5-10 minutes until uniformly dispersed; and turning on the heating, adding the chelating agent and the preservative, heating to 75-85° C., and stirring for 5-15 minutes to obtain a mixture a;

[0048] S2: adding the emollient and chemical sunscreen into an oil pan, heating and stirring to dissolve, heating to 70-80° C. until completely dissolved, then adding the film former and emulsifier in the sunscreen composition, maintaining the temperature at 70-80° C. and stirring to completely dissolve to obtain a mixture b;

[0049] S3: preheat the emulsifier to 60°C, pump mixture a into the emulsifier, cool mixture b to 60°C and add it into the emulsifier, start homogenization, the homogenization speed is 3000-3500rpm, the homogenization time is 5-10min, and after mixing evenly, start stirring and cooling;

[0050] S4: Cool down to 40-45°C, add physical sunscreen first, homogenize at a speed of 1000-1500 rpm, homogenize for 3-8 minutes until mixed evenly, then add moisturizer b, plant extract in the sunscreen composition, skin protectant a, skin protectant b, pH adjuster, stir for 5-10 minutes until mixed evenly to obtain an oil-in-water sunscreen lotion preparation.

[0051] Furthermore, after adding a pH adjuster, the pH of the oil-in-water sunscreen lotion preparation is adjusted to within the range of 5.5-6.5 to be a qualified product.

[0052] A fourth aspect of the present invention provides a sunscreen composition for use in the field of cosmetic technology.

[0053] A fourth aspect of the present invention provides a sunscreen composition for use in the technical field of cosmetics such as emulsions and creams.

[0054] Beneficial Effects

[0055] 1. The sunscreen composition and the sunscreen composition provided by the present invention are suitable for use in water-in-oil sunscreen lotion preparations, have the characteristics of being refreshing and non-greasy, non-mud-causing, non-acne-causing, light burden, waterproof and non-allergenic, and are suitable for use by people with oily skin and sensitive skin who need sun protection.

[0056] 2. The sunscreen composition provided by the present invention and the sunscreen composition containing the sunscreen composition are suitable for water-in-oil sunscreen lotion preparations, which have a mild, clear and light experience, and also have good stability and waterproof performance.

[0057] 3. The present invention greatly reduces the amount of emulsifier used by limiting the types and ratios of raw materials used for thickeners, film formers, emulsifiers and plant extracts, improves the safety and stability of sunscreen products, and provides more advantages for the oil-in-water sunscreen lotion preparation provided by the present invention in applications on sensitive skin.

[0058] 4. The present invention limits the type and ratio of the thickener, thereby solving the problem of flocculation of physical sunscreen in an oil-in-water emulsion system, which causes the oil-water separation in the oil-in-water emulsion system.

[0059] 5. By adopting the sunscreen composition, sunscreen, emollient, moisturizer, preservative, chelating agent, pH adjuster, skin protectant and water as defined in the present invention, the fluidity of the oil-in-water sunscreen lotion preparation can be improved, and the preparation has the effects of easy application, light burden and good stability. It is especially suitable for people with sensitive skin, and is particularly suitable for daily sun protection use by people with oily sensitive skin.

[0060] 6. The oil-in-water sunscreen lotion provided by the present invention will not irritate the skin, will not cause redness, burning, or stinging, and is safe to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] Figure 1 Regarding the content of the sun protection factor test method1.

[0062] Figure 2 Content 2 about sun protection factor testing method.

[0063] Figure 3 About the SPF value testing method.

[0064] Figure 4 For the SPF value test results.

[0065] Figure 5 It is a testing method for the SPF value of human body after bathing.

[0066] Figure 6 This is the test result of SPF value on human body after bathing.

[0067] Figure 7 This is the test method for the UV protection index PFA value.

[0068] Figure 8 The test results of UV protection index PFA value. DETAILED DESCRIPTION

[0069] Example 1

[0070] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.4 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0071] The plant extract comprises asiatica glycoside and madecassoside.

[0072] The emulsifier is glyceryl stearate / polyethylene glycol-100 stearate.

[0073] The thickener is a combination of xanthan gum and carbomer.

[0074] The film former is VP / eicosene copolymer.

[0075] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.43% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH adjuster, 3.5% skin protectant, and the balance water; the sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b. The moisturizer includes moisturizer a and moisturizer b;

[0076] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0077] The skin protective agent a is aluminum starch octenylsuccinate.

[0078] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0079] The water is purified water.

[0080] The pH regulator is a combination of sodium citrate and arginine, and the weight ratio of the sodium citrate to arginine is 1:2.

[0081] The preservative is p-hydroxyacetophenone.

[0082] The chelating agent is disodium EDTA.

[0083] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0084] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0085] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0086] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0087] A third aspect of the present embodiment provides a method for preparing an oil-in-water sunscreen lotion preparation, comprising the following steps:

[0088] S1: pre-moistening the thickener in the sunscreen composition with moisturizer a until uniform, then adding it into water and stirring for 8 minutes until uniformly dispersed; and then turning on the heating, adding the chelating agent and the preservative, heating to 80° C., and stirring for 10 minutes to obtain a mixture a;

[0089] S2: adding the emollient and chemical sunscreen into an oil pan, heating and stirring to dissolve, heating to 75° C. until completely dissolved, then adding the film former and emulsifier in the sunscreen composition, maintaining the temperature at 75° C. and stirring to completely dissolve to obtain a mixture b;

[0090] S3: preheat the emulsifier to 60°C, pump mixture a into the emulsifier, cool mixture b to 60°C and add it to the emulsifier, start homogenization, the homogenization speed is 3300rpm, the homogenization time is 8min, and after mixing evenly, start stirring and cooling;

[0091] S4: Cool down to 45°C, add physical sunscreen first, homogenize at 1500 rpm, homogenize for 5 minutes until mixed evenly, then add moisturizer b, plant extract in the sunscreen composition, skin protectant a, skin protectant b, pH adjuster, stir for 8 minutes until mixed evenly to obtain an oil-in-water sunscreen lotion preparation.

[0092] After adding the pH adjuster, the pH of the water-in-oil sunscreen preparation is adjusted to 5.5-6.5, which is a qualified product.

[0093] A fourth aspect of this embodiment provides an application of a sunscreen composition in the field of cosmetic technology.

[0094] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0095] Example 2

[0096] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0097] The plant extract comprises asiatica glycoside and madecassoside.

[0098] The thickener is a composition of xanthan gum and acrylic acid (esters) / C10-30 alkyl acrylate cross-linked polymer.

[0099] The emulsifier is glyceryl stearate / polyethylene glycol-100 stearate.

[0100] The film former is VP / eicosene copolymer.

[0101] The second aspect of the present embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.33% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH regulator, 3.5% skin protectant, and the balance water; the sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0102] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0103] The skin protective agent a is aluminum starch octenylsuccinate.

[0104] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0105] The water is purified water.

[0106] The pH regulator is a combination of sodium citrate and arginine, and the weight ratio of the sodium citrate to arginine is 1:2.

[0107] The preservative is p-hydroxyacetophenone.

[0108] The chelating agent is disodium EDTA.

[0109] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0110] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0111] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0112] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0113] The preparation method and application are the same as in Example 1.

[0114] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0115] Example 3

[0116] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.4 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0117] The plant extract comprises asiatica glycoside and madecassoside.

[0118] The thickener is a composition of sodium polyacrylate and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer.

[0119] The emulsifier is beheneth-25.

[0120] The film former is VP / eicosene copolymer.

[0121] The second aspect of the present embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.43% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.05% pH adjuster, 3.5% skin protectant, and the balance water; the sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0122] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0123] The skin protective agent a is aluminum starch octenylsuccinate.

[0124] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0125] The water is purified water.

[0126] The pH adjuster is sodium citrate.

[0127] The preservative is p-hydroxyacetophenone.

[0128] The chelating agent is disodium EDTA.

[0129] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0130] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0131] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0132] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0133] The preparation method and application are the same as in Example 1.

[0134] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0135] Example 4

[0136] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.4 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0137] The plant extract comprises asiatica glycoside and madecassoside.

[0138] The thickener is a composition of sodium polyacrylate and xanthan gum.

[0139] The emulsifier is beheneth-25.

[0140] The film former is VP / eicosene copolymer.

[0141] The second aspect of the present embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.43% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.05% pH adjuster, 3.5% skin protectant, and the balance water; the sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0142] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0143] The skin protective agent a is aluminum starch octenylsuccinate.

[0144] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0145] The water is purified water.

[0146] The pH adjuster is sodium citrate.

[0147] The preservative is p-hydroxyacetophenone.

[0148] The chelating agent is disodium EDTA.

[0149] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0150] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0151] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0152] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0153] The preparation method and application are the same as in Example 1.

[0154] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0155] Example 5

[0156] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.4 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0157] The plant extract comprises asiatica glycoside and madecassoside.

[0158] The emulsifier is glyceryl stearate / polyethylene glycol-100 stearate.

[0159] The thickener is a combination of xanthan gum and carbomer.

[0160] The film former is VP / eicosene copolymer.

[0161] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.43% sunscreen composition, 15% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH regulator, 3.5% skin protectant, and the balance water. The skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0162] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0163] The skin protective agent a is aluminum starch octenylsuccinate.

[0164] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0165] The water is purified water.

[0166] The pH regulator is a combination of sodium citrate and arginine, and the weight ratio of the sodium citrate to arginine is 1:2.

[0167] The preservative is p-hydroxyacetophenone.

[0168] The chelating agent is disodium EDTA.

[0169] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0170] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0171] The sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0172] A third aspect of the present embodiment provides a method for preparing an oil-in-water sunscreen lotion preparation, comprising the following steps:

[0173] S1: pre-moistening the thickener in the sunscreen composition with moisturizer a until uniform, then adding it into water and stirring for 8 minutes until uniformly dispersed; and then turning on the heating, adding the chelating agent and the preservative, heating to 80° C., and stirring for 10 minutes to obtain a mixture a;

[0174] S2: adding the emollient and chemical sunscreen into an oil pan, heating and stirring to dissolve, heating to 75° C. until completely dissolved, then adding the film former and emulsifier in the sunscreen composition, maintaining the temperature at 75° C. and stirring to completely dissolve to obtain a mixture b;

[0175] S3: preheat the emulsifier to 60°C, pump mixture a into the emulsifier, cool mixture b to 60°C and add it to the emulsifier, start homogenization, the homogenization speed is 3300rpm, the homogenization time is 8min, and after mixing evenly, start stirring and cooling;

[0176] S4: Cooling to 45° C., adding moisturizer b, plant extract in the sunscreen composition, skin protectant a, skin protectant b, and pH adjuster, stirring for 8 minutes until the mixture is evenly mixed to obtain an oil-in-water sunscreen lotion preparation.

[0177] After adding the pH adjuster, the pH of the water-in-oil sunscreen preparation is adjusted to 5.5-6.5, which is a qualified product.

[0178] A fourth aspect of this embodiment provides an application of a sunscreen composition in the field of cosmetic technology.

[0179] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0180] Example 6

[0181] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.4 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0182] The plant extract comprises asiatica glycoside and madecassoside.

[0183] The emulsifier is beheneth-25.

[0184] The thickener is a composition of xanthan gum and sodium polyacrylate.

[0185] The film former is VP / eicosene copolymer.

[0186] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.43% sunscreen composition, 15% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH regulator, 3.5% skin protectant, and the balance water. The skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0187] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0188] The skin protective agent a is aluminum starch octenylsuccinate.

[0189] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0190] The water is purified water.

[0191] The pH adjuster is sodium citrate.

[0192] The preservative is p-hydroxyacetophenone.

[0193] The chelating agent is disodium EDTA.

[0194] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0195] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0196] The sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0197] The preparation method and application are the same as those in Example 5.

[0198] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0199] Example 7

[0200] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 1 part of a film former, 3 parts of an emulsifier, and 0.02 parts of a plant extract, in parts by weight.

[0201] The plant extract comprises asiatica glycoside and madecassoside.

[0202] The emulsifier is beheneth-25.

[0203] The thickener is a composition of xanthan gum and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, and the weight ratio of acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer to xanthan gum is 1:2.

[0204] The film former is VP / eicosene copolymer.

[0205] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 4.32% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.05% pH adjuster, 3.5% skin protectant, and the balance water. The sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0206] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0207] The skin protective agent a is aluminum starch octenylsuccinate.

[0208] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0209] The water is purified water.

[0210] The pH adjuster is sodium citrate.

[0211] The preservative is p-hydroxyacetophenone.

[0212] The chelating agent is disodium EDTA.

[0213] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0214] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0215] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0216] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0217] The preparation method and application are the same as in Example 1.

[0218] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0219] Example 8

[0220] The first aspect of the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 1 part of a film former, 0.2 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0221] The plant extract comprises asiatica glycoside and madecassoside.

[0222] The emulsifier is beheneth-25.

[0223] The thickener is a composition of xanthan gum and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, and the weight ratio of the acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer to the xanthan gum is 2:1.

[0224] The film former is VP / eicosene copolymer.

[0225] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 1.53% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH adjuster, 4.2% skin protectant, and the balance water. The sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0226] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0227] The skin protective agent a is aluminum starch octenylsuccinate.

[0228] The skin protectant b is a composition of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol combination.

[0229] The water is purified water.

[0230] The pH regulator is a combination of sodium citrate and arginine.

[0231] The preservative is p-hydroxyacetophenone.

[0232] The chelating agent is disodium EDTA.

[0233] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0234] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0235] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0236] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0237] The preparation method and application are the same as in Example 1.

[0238] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0239] Example 9

[0240] In a first aspect, the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 0.8 parts of a film former, 0.2 parts of an emulsifier, and 0.03 parts of a plant extract, in parts by weight.

[0241] The plant extract comprises asiatica glycoside and madecassoside.

[0242] The emulsifier is beheneth-25.

[0243] The thickener is a composition of xanthan gum and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, and the weight ratio of the acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer to the xanthan gum is 2:1.

[0244] The film former is VP / eicosene copolymer.

[0245] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 1.33% sunscreen composition, 17% sunscreen agent, 5% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH adjuster, 4.4% skin protectant, and the balance water. The sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0246] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0247] The skin protective agent a is aluminum starch octenylsuccinate.

[0248] The skin protectant b is composed of a combination of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol and a combination of LOTUS CORNICULATUS seed extract / 1,3-propylene glycol / water.

[0249] The water is purified water.

[0250] The pH regulator is a combination of sodium citrate and arginine.

[0251] The preservative is p-hydroxyacetophenone.

[0252] The chelating agent is disodium EDTA.

[0253] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0254] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0255] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0256] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0257] The preparation method and application are the same as in Example 1.

[0258] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0259] Example 10

[0260] In a first aspect, the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 1 part of a film former, 0.3 parts of an emulsifier, and 0.2 parts of a plant extract, in parts by weight.

[0261] The plant extract comprises asiatica glycoside and madecassoside.

[0262] The emulsifier is beheneth-25.

[0263] The thickener is a composition of xanthan gum and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, and the weight ratio of the acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer to the xanthan gum is 2:1.

[0264] The film former is VP / eicosene copolymer.

[0265] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 1.8% sunscreen composition, 15.8% sunscreen agent, 4% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.15% pH adjuster, 4.7% skin protectant, and the balance is water. The sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0266] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0267] The skin protective agent a is aluminum starch octenylsuccinate.

[0268] The skin protectant b is composed of a combination of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol and a combination of LOTUS CORNICULATUS seed extract / 1,3-propylene glycol / water.

[0269] The water is purified water.

[0270] The pH regulator is a combination of sodium citrate and arginine.

[0271] The preservative is p-hydroxyacetophenone.

[0272] The chelating agent is disodium EDTA.

[0273] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0274] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0275] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0276] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0277] The preparation method and application are the same as in Example 1.

[0278] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0279] Embodiment 11

[0280] In a first aspect, the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 1 part of a film former, 1 part of an emulsifier, and 0.2 parts of a plant extract, in parts by weight.

[0281] The plant extract comprises asiatica glycoside and madecassoside.

[0282] The emulsifier is beheneth-25.

[0283] The thickener is a composition of xanthan gum and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, and the weight ratio of acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer to xanthan gum is 1:2.

[0284] The film former is VP / eicosene copolymer.

[0285] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 2.5% sunscreen composition, 15.8% sunscreen agent, 4% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.05% pH adjuster, 5% skin protectant, and the balance water. The sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0286] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0287] The skin protective agent a is aluminum starch octenylsuccinate.

[0288] The skin protectant b is composed of a combination of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol and a combination of LOTUS CORNICULATUS seed extract / 1,3-propylene glycol / water.

[0289] The water is purified water.

[0290] The pH adjuster is sodium citrate.

[0291] The preservative is p-hydroxyacetophenone.

[0292] The chelating agent is disodium EDTA.

[0293] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0294] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0295] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0296] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0297] The preparation method and application are the same as in Example 1.

[0298] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0299] Example 12

[0300] In a first aspect, the present embodiment provides a sunscreen composition, wherein the raw materials for preparing the sunscreen composition consist of 0.3 parts of a thickener, 1 part of a film former, 1 part of an emulsifier, and 0.5 parts of a plant extract, in parts by weight.

[0301] The plant extract comprises asiatica glycoside and madecassoside.

[0302] The emulsifier is beheneth-25.

[0303] The thickener is a composition of xanthan gum and acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer, and the weight ratio of acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer to xanthan gum is 1:2.

[0304] The film former is VP / eicosene copolymer.

[0305] The second aspect of this embodiment provides an oil-in-water sunscreen lotion preparation, wherein the raw materials for its preparation include, by mass percentage, 2.8% sunscreen composition, 15.8% sunscreen agent, 4% emollient, 4% moisturizer, 0.2% preservative, 0.1% chelating agent, 0.05% pH adjuster, 5% skin protectant, and the balance is water. The sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the skin protectant includes skin protectant a and skin protectant b; the moisturizer includes moisturizer a and moisturizer b;

[0306] The moisturizing agent a is butylene glycol, and the moisturizing agent b is 1,2-pentanediol.

[0307] The skin protective agent a is aluminum starch octenylsuccinate.

[0308] The skin protectant b is composed of a combination of MAGNOLIA BIONDII flower extract / 1,3-propylene glycol and a combination of LOTUS CORNICULATUS seed extract / 1,3-propylene glycol / water.

[0309] The water is purified water.

[0310] The pH adjuster is sodium citrate.

[0311] The preservative is p-hydroxyacetophenone.

[0312] The chelating agent is disodium EDTA.

[0313] The moisturizing agent is a composition of butylene glycol and 1,2-pentanediol.

[0314] The emollient is a combination of dibutyl adipate and propylheptyl octanoate.

[0315] The physical sunscreen is a composition consisting of titanium dioxide / caprylic acid / capric acid triglyceride / silica / jojoba esters / polyhydroxystearic acid.

[0316] The chemical sunscreen is ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone, diethylaminohydroxybenzoyl hexyl benzoate, and a composition consisting of methylene bis-benzotriazolyl tetramethylbutylphenol / water / decyl glucoside / propylene glycol / xanthan gum.

[0317] The preparation method and application are the same as in Example 1.

[0318] The specific amounts of raw materials are shown in Table 2, and the manufacturers and models of raw materials are shown in Table 1.

[0319] Table 2

[0320]

[0321] Table 2

[0322]

[0323] Performance Testing

[0324] 1. Centrifugal stability test

[0325] The oil-in-water sunscreen lotion preparations prepared in Examples 1-12 were subjected to a centrifugal acceleration test to test whether the oil-in-water sunscreen lotion system had flocculation and oil-water separation. Flocculation refers to the incompatibility of physical sunscreen agents with chemical sunscreen agents or other substances, and local precipitation of particles. Oil-water stratification refers to the instability of the oil-in-water system, and the separation of oil or sunscreen agents. The test results are shown in Table 4.

[0326] 2. High and low temperature stability test

[0327] The oil-in-water sunscreen lotion preparations prepared in Examples 1-12 were subjected to centrifugal acceleration tests. Based on the test results, the oil-in-water sunscreen lotion preparations prepared in Examples 6-11 were subjected to high and low temperature damage tests (under -15°C and 42°C conditions, tested for 30 days, 60 days and 90 days, respectively). The test results are shown in Table 5.

[0328] 3. Security Testing

[0329] Description: Zebrafish is one of the surrogate species currently used in human health and ecological hazard assessments. The toxicity response of zebrafish can predict the toxicity response of mammals. Skin exposed to toxic and hazardous substances in the living environment may cause a certain degree of skin inflammation, such as skin redness, swelling, and itching. Sodium dodecyl sulfate (SLS) is a common positive control in human skin irritant model patch tests. SLS can induce epidermal inflammatory cell infiltration after stimulation. The irritant enters the body of zebrafish and induces an inflammatory response. Under the stimulation of SLS, the median lethal concentration (LC50) of the sample is determined by the mortality rate of zebrafish. The larger the LC50 value, the higher the safety of the sample.

[0330] Test method steps:

[0331] 1. Randomly select zebrafish and place them in 6-well plates, with 30 zebrafish in each well.

[0332] 2. A zebrafish skin inflammation model was established by administering sodium dodecyl sulfate (SLS) in a water-soluble manner, wherein the mass concentration of SLS in water was 0.006%.

[0333] 3. Water-soluble The oil-in-water sunscreen lotion preparations prepared in Examples 6-11 were respectively added, and the capacity of each well was 3 mL.

[0334] 4. Incubate at 28°C in the dark for 18 h.

[0335] 5. After the experiment, the mortality rate of zebrafish in each group was counted, and the median lethal concentration (LC50) of the oil-in-water sunscreen lotion prepared in Examples 6-11 in water for zebrafish was analyzed and calculated using SPSS 26.0 software. The test results are shown in Table 6.

[0336] 4. Skin irritation test

[0337] In order to further verify the safety of the oil-in-water sunscreen lotion prepared in the examples of the present application, combined with the centrifugal stability test results, high and low temperature stability test results and safety test results obtained in the examples of the present application, with reference to the "Technical Specification for Safety of Cosmetics" (2015 edition), the oil-in-water sunscreen lotion prepared in Example 9 was selected to conduct multiple skin irritation tests on New Zealand rabbits, and the results were scored. The results are shown in Table 7.

[0338] 5. Sun protection index test

[0339] In order to verify the sun protection index of the sunscreen composition and the oil-in-water sunscreen lotion preparation, combined with the stability test data of different embodiments tested in this application and the zebrafish LC50 data, the oil-in-water sunscreen lotion preparations prepared in Examples 8, 9 and 10 are preferably subjected to in vitro SPF / PA value testing.

[0340] Test method content see Figure 1 and Figure 2 ; The test results are shown in Table 8.

[0341] Sunscreen and waterproof test

[0342] The oil-in-water sunscreen lotion prepared in Example 9 was selected to test the in vitro SPF value, the SPF value after human bathing, and the ultraviolet protection index PFA value; the SPF value test method is described in Figure 3 , test results see Figure 4 ; The content of the SPF value test method for human body after bathing is shown in Figure 5 , test results see Figure 6 ; The UV protection index PFA value test method content see Figure 7 , test results see Figure 8 .

[0343] pass Figure 4 It can be seen that the SPF value obtained after human body testing is 51, which meets the application requirements of SPF50+. Figure 6 It can be seen that the SPF value of the human body after bathing for 40 minutes is 30, which shows that after bathing for 40 minutes, the water-in-oil sunscreen lotion prepared in Example 9 still has a certain performance of resisting ultraviolet rays, and the SPF value retention rate is greater than 50%, which shows that the water-in-oil sunscreen lotion prepared in this application has excellent waterproof performance. Figure 8 It can be seen that the PFA value obtained by testing after ultraviolet irradiation is 8, and the oil-in-water sunscreen lotion prepared in Example 9 has excellent resistance to ultraviolet radiation.

[0344] Table 4

[0345]

[0346] It can be seen from the test results of Examples 1, 2, 3, 4, and 12 in Table 4 that the oil-in-water sunscreen lotion preparation prepared from the raw material system containing physical sunscreen agents will easily cause system flocculation and oil-water separation during centrifugation after high-speed centrifugation due to the physical sunscreen agents in the oil-in-water emulsion system; it can be seen from the test results of Examples 5 and 6 that the sunscreen lotion preparation using chemical sunscreen agents alone does not have the problem of flocculation during high-speed centrifugation; by comparing the test results of Examples 7, 8, 9, 10, 11, and 12 with those of Examples 1, 2, 3, and 4, it can be seen that the problem of flocculation and oil-water separation of physical sunscreen agents in the oil-in-water emulsion system can be solved by using specific physical sunscreen agents and chemical sunscreen agents in combination; it can be seen from the test results of Examples 7 and 11 that increasing the use content of the emulsifier can also improve the stability of the physical sunscreen agent compounded with the chemical sunscreen agent in the oil-in-water emulsion system.

[0347] Table 5

[0348]

[0349] It can be seen from the test results in Table 5 that in the process of preparing the oil-in-water sunscreen lotion preparation, Examples 6, 8, 9, and 10 of the present application use specific physical sunscreens and chemical sunscreens for combined use, which can improve the storage stability of the oil-in-water sunscreen lotion preparation at high and low temperatures. It can be seen from Examples 7 and 11 that when the amount and ratio of raw materials such as emulsifiers, thickeners, and plant extracts in the sunscreen composition are not within the range specified in the present application, it will affect the storage stability of the oil-in-water sunscreen lotion preparation at high and low temperatures, and ultimately affect the life cycle of the product.

[0350] Table 6

[0351]

[0352] As can be seen from Table 6, under the experimental conditions, the LC50 of the oil-in-water sunscreen lotion preparations prepared in Examples 6, 7, 8, 9, 10, and 11 under SLS irritation were 1.19%, 1.86%, 4.07%, 4.27%, 3.73%, and 3.05%, respectively; Examples 9 and 8 had the highest LC50 values. It is speculated that when the emulsifier content is low and the acrylic acid (ester) / C10-30 alkyl acrylate crosslinked polymer: xanthan gum is preferably 0.2% and 0.1%, the safety of the oil-in-water sunscreen lotion preparation of the present invention can be improved and the probability of adverse reactions can be reduced.

[0353] Table 7

[0354]

[0355] The test results in Table 7 show that the oil-in-water sunscreen lotion prepared in Example 9 of the present application has the following multiple skin irritations to rabbits: no irritation; mild and non-irritating, does not cause redness, burning, or stinging, is safe to use, and can meet marketing requirements.

[0356] Table 8

[0357]

[0358] It can be seen from the test results in Table 8 that the test results of Examples 9 and 10 have little difference, and the SPF value is better than that of Example 8. It can be seen that the sunscreen composition uses a specific ratio of emulsifier in combination with physical sunscreen and chemical sunscreen, which has a positive effect on the sun protection index. Combined with the zebrafish safety test conducted on Examples 8, 9 and 10, it can be seen that the sunscreen composition and water-in-oil sunscreen lotion preparation corresponding to Example 9 better meet the requirements for listing, can solve the technical problems of this industry, and provide consumers with a safe, mild, stable and clear water-in-oil sunscreen lotion product.

Claims

1. A sunscreen composition, characterized in that: The raw materials for its preparation include 0.1-0.5 parts of thickener, 0.5-1.5 parts of film former, 0.1-1 parts of emulsifier and 0.02-2 parts of plant extract by weight; The thickener is acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer and xanthan gum, and the weight ratio of acrylic acid (ester) / C10-30 alkyl acrylate cross-linked polymer and xanthan gum is 2:1; The film former is VP / eicosene copolymer; The emulsifier is beheneth-25; The plant extract comprises asiatica glycoside and madecassoside.

2. An oil-in-water sunscreen lotion preparation, characterized in that: The invention comprises the sunscreen composition according to claim 1.

3. The oil-in-water sunscreen lotion preparation according to claim 2, characterized in that: The raw materials for its preparation include, by mass percentage, 0.75-8.7% of sunscreen composition, 10.0-20.0% of sunscreen agent, 5.0-15.0% of emollient, 3.0-8.0% of moisturizer, 0.1-3.2% of preservative, 0.05-0.2% of chelating agent, 0.01-0.2% of pH adjuster, 1.0-8.0% of skin protectant, and the remainder of water; the sunscreen agent includes chemical sunscreen agent and physical sunscreen agent; the moisturizer includes moisturizer a and moisturizer b; the skin protectant includes skin protectant a and skin protectant b.

4. A method for preparing the oil-in-water sunscreen lotion preparation according to claim 3, characterized in that: The following steps are involved: S1: pre-moistening the thickener in the sunscreen composition with moisturizer a until uniform, then adding it into water and stirring for 5-10 minutes until uniformly dispersed; and turning on the heating, adding the chelating agent and the preservative, heating to 75-85° C., and stirring for 5-15 minutes to obtain a mixture a; S2: adding the emollient and chemical sunscreen into an oil pan, heating and stirring to dissolve, heating to 70-80° C. until completely dissolved, then adding the film former and emulsifier in the sunscreen composition, maintaining the temperature at 70-80° C. and stirring to completely dissolve to obtain a mixture b; S3: preheat the emulsifier to 60°C, pump mixture a into the emulsifier, cool mixture b to 60°C and add it into the emulsifier, start homogenization, the homogenization speed is 3000-3500rpm, the homogenization time is 5-10min, and after mixing evenly, start stirring and cooling; S4: Cool down to 40-45°C, add physical sunscreen first, homogenize at a speed of 1000-1500 rpm, homogenize for 3-8 minutes until mixed evenly, then add moisturizer b, plant extract in the sunscreen composition, skin protectant a, skin protectant b, pH adjuster, stir for 5-10 minutes until mixed evenly to obtain an oil-in-water sunscreen lotion preparation.

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