Traditional Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar and preparation method thereof
By developing a traditional Chinese medicine composition containing a variety of Chinese herbal medicines, using enzymatic decomposition and water extraction processes, the side effects and long-term use of existing hyperglycemia drugs have been solved, and the effects of activating the pancreas, stabilizing blood sugar and reducing complications have been achieved.
Patent Information
- Application Number
- CN202310470043.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-04-27
- Publication Date
- 2025-02-21
- Estimated Expiration
- 2043-04-27
AI Technical Summary
There are many drugs used to prevent and treat hyperglycemia, and long-term use will cause harm to the body. There is a lack of effective drugs that have no side effects and can be consumed for a long time.
Develop a traditional Chinese medicine composition, including Astragalus, ginseng, yam, Polygonatum, Rehmannia glutinosa, Ligustrum, Cuscuta, wolfberry, Atractylodes, Atractylodes and Pueraria root, and prepare a control of glycemic and turbidity through enzymatic decomposition and water extraction. Traditional Chinese medicine composition for blood sugar.
This traditional Chinese medicine composition can activate the pancreas, restore self-healing ability, accelerate microcirculation and metabolism, excrete toxins, and has the effect of nourishing and repairing cells, stabilize blood sugar, reduce the occurrence of complications, and promote the body to recover health.
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Abstract
Description
Technical Field
[0001] The invention relates to a Chinese medicine composition and a preparation method thereof, in particular to a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar and a preparation method thereof. Background Art
[0002] At present, there are many people with a high incidence of diabetes, and the complications of late diabetes seriously threaten people's life safety. Under normal circumstances, the normal value of fasting blood sugar is 4.0-6.1mmol / L. If the fasting blood sugar (no sugar and any sugary food intake within 8 hours) is higher than the normal range, it is considered a symptom of hyperglycemia. When the blood sugar is higher than the normal range of 7.8mmol / L two hours after a meal, it can also be considered hyperglycemia. Hyperglycemia is not a diagnosis of a disease, but only a determination of the results of blood sugar monitoring. Blood sugar monitoring is a temporary result. Hyperglycemia is not completely equal to diabetes, but hyperglycemia is likely to be an early symptom of diabetes. At present, the population of diabetic patients is getting younger and younger, and even children with diabetes have appeared. Therefore, early treatment is required when hyperglycemia is detected. At present, there are more and more drugs used in clinical practice to prevent and treat hyperglycemia, but most of them have certain side effects. If taken for a long time, it will cause varying degrees of damage to the body. For people with high blood sugar, three-point treatment and seven-point care are the basic principles. Therefore, it is necessary to develop a drug that can play a better preventive and therapeutic role, has no side effects, and can be taken for a long time. Summary of the invention
[0003] In view of the above problems, the present invention provides a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar and a preparation method thereof.
[0004] To achieve the above purpose, the technical solution adopted by the present invention is:
[0005] A Chinese medicine composition for reducing blood sugar and clearing turbidity to control blood sugar, wherein the raw materials for making the Chinese medicine composition for reducing blood sugar and clearing turbidity to control blood sugar include, by weight:
[0006] 25-35 parts of Astragalus, 10-15 parts of Ginseng, 20-25 parts of Dioscorea, 18-20 parts of Polygonatum, 20-25 parts of Rehmannia, 12-15 parts of Ligustrum lucidum, 12-15 parts of Cuscuta, 15-20 parts of Lycium barbarum, 10-12 parts of Atractylodes, 12-15 parts of Cyperus and 10-15 parts of Pueraria.
[0007] A method for preparing the above-mentioned Chinese medicine composition for lowering blood sugar, removing turbidity and controlling blood sugar. The preparation method is to take astragalus, ginseng, yam, polygonatum, raw rehmannia, Ligustrum lucidum, dodder seed, wolfberry, atractylodes, cyperus and kudzu root, add water and boil them, and then concentrate and dry them to obtain the Chinese medicine composition for lowering blood sugar, removing turbidity and controlling blood sugar.
[0008] A method for preparing the above-mentioned Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar, the preparation method comprising the following steps:
[0009] 1) Take eight medicinal materials, including astragalus, ginseng, polygonatum, glossy privet, dodder, wolfberry, atractylodes and kudzu root, add them to citric acid buffer, add complex enzyme composed of cellulase, pectinase and papain, perform enzymolysis, boil and inactivate enzymes, filter and obtain eight medicinal liquids;
[0010] Take three herbs, namely, Radix Rehmanniae, Rhizoma Dioscoreae and Rhizoma Cyperi, add water to boil and extract, filter and obtain three herbs liquid;
[0011] 2) After the eight medicinal liquids are mixed with the three medicinal liquids, they are concentrated and dried to obtain the Chinese medicine composition for lowering blood sugar, removing turbidity and controlling blood sugar.
[0012] Furthermore, in step 1), the complex enzyme is composed of cellulase, pectinase and papain in a weight ratio of 1:0.9-1.1:0.9-1.1.
[0013] Furthermore, in step 1), the dosage of the complex enzyme is 1.8-2.0 wt % of the total weight of the eight medicinal materials.
[0014] Furthermore, in step 1), the pH value of the citric acid buffer is 5 to 5.6.
[0015] Furthermore, in step 1), the amount of the citric acid buffer is 8 to 10 times the total weight of the eight medicinal materials;
[0016] The amount of water used is 8 to 10 times the total weight of the three medicinal materials.
[0017] Furthermore, in step 1), the temperature of enzymolysis is 40-45° C. and the time is 0.5-1 h.
[0018] Furthermore, in step 2), after the eight medicinal liquids are mixed with the three medicinal liquids, dextrin needs to be added and mixed before the obtained medicinal liquid is concentrated.
[0019] Furthermore, the added amount of the dextrin is 5 to 8 parts by weight.
[0020] The beneficial effects of the Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar and the preparation method thereof of the present invention are:
[0021] The Chinese medicine composition for reducing blood sugar and removing turbidity and controlling blood sugar of the present invention can activate the pancreas, restore the self-healing ability of the pancreas, accelerate the metabolism of human microcirculation and various functions, and discharge toxins and garbage in the body; the Chinese medicinal materials with specific dosages of medicine and food are used to cooperate with each other to achieve the purpose of nourishing and repairing cells, and has the effects of removing turbidity and detoxification, regulating the spleen and kidney, unblocking meridians, removing stasis, activating qi and blood, and regulating the spleen, thereby awakening and restoring the body's self-healing function, freeing diabetic patients from the pain of long-term medication, reducing the occurrence of complications, and restoring the body to health;
[0022] The present invention selects Chinese medicinal materials such as ginseng, astragalus, yam, polygonatum, raw rehmannia, glossy privet, dodder seed, wolfberry, atractylodes, cyperus, kudzu root and the like as raw materials. These Chinese medicinal materials have the functions of invigorating qi and nourishing yin, promoting blood circulation and removing blood stasis, removing turbidity and detoxifying, strengthening the body and nourishing the essence, and warming and unblocking the meridians. Through a specific preparation process, the efficacy of the original medicine is fully retained, the volume of the stem and leaf Chinese herbal medicine is reduced, and it is convenient to carry and store, so as to achieve the clinical effects of raising the clear and lowering the turbid, regulating qi and blood, nourishing the internal organs, activating the pancreatic function, stabilizing blood sugar, maintaining and repairing damaged cells, regulating the functions of the internal organs and meridians, and promoting the detoxification function of the internal organs;
[0023] The present invention processes the medicinal materials by classification, effectively extracts and retains the effective ingredients in the Chinese medicinal materials, and improves the efficacy of the products;
[0024] The present invention adopts an enzyme treatment method, selects specific process parameters and complex enzymes, and performs co-enzymatic hydrolysis on eight medicinal materials, thereby effectively releasing the effective components in the Chinese medicinal materials; and for the three medicinal materials of Radix Rehmanniae, Rhizoma Dioscoreae and Rhizoma Cyperi, especially Rhizoma Cyperi with certain toxicity, water extraction is adopted to extract the three medicinal materials, while ensuring the extraction of effective components, toxic substances are prevented from mixing into the three medicinal liquids;
[0025] The present invention can fully ensure the enzymatic hydrolysis effect and effectively release the active ingredients in the Chinese medicinal materials by selecting a citric acid buffer with a specific pH as the enzymatic hydrolysis solvent, and selecting a specific temperature and enzymatic hydrolysis time;
[0026] The invention can encapsulate the volatile oil in the medicinal liquid by adding dextrin into the medicinal liquid obtained after mixing, thereby reducing the volatilization of the volatile oil in the medicinal liquid during the concentration process. DETAILED DESCRIPTION
[0027] The technical solutions in the embodiments of the present invention are described clearly and completely below. In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention can also be implemented in other ways different from those described herein, and those skilled in the art can make similar generalizations without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.
[0028] Example 1 Preparation method of a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar
[0029] This embodiment is a method for preparing a Chinese medicine composition for reducing blood sugar and clearing turbidity to control blood sugar, and the specific preparation process includes the following steps:
[0030] Take 35kg of Astragalus, 12kg of Ginseng, 25kg of Chinese Yam, 20kg of Polygonatum, 25kg of Rehmannia, 15kg of Ligustrum lucidum, 15kg of Cuscuta australis, 20kg of Lycium barbarum, 12kg of Atractylodes, 12kg of Cyperus rotundus, and 12kg of Pueraria, add 10 times the weight of water and boil twice (i.e., boil twice with 20-30kg of water), each time for 1 hour, combine the decoctions, add 6kg of dextrin, stir and mix, concentrate, spray dry, and dry granulate to obtain 25.7kg of a Chinese medicine composition for lowering blood sugar, removing turbidity and controlling blood sugar, with a total extraction rate of 9.70%, marked as J1.
[0031] Wherein, the extraction rate (%) = (the weight of the Chinese medicine composition for reducing blood sugar and removing turbidity to control blood sugar - the amount of dextrin added) ÷ the total weight of the medicinal materials × 100%.
[0032] The Chinese medicine composition J1 for lowering blood sugar, removing turbidity and controlling blood sugar contains 0.250 g / kg of astragaloside IV, 4.971 g / kg of total ginsenosides of Panax notoginseng, 0.046 g / kg of hyperoside, 0.201 g / kg of oleanolic acid and 0.280 g / kg of atractylodesin.
[0033] Astragaloside IV was determined according to the method described in "Comparative Study on the Content of Active Ingredients of Astragalus from Different Producing Areas in Gansu" (Wang Ting et al., Journal of Traditional Chinese Veterinary Medicine, Vol. 40, No. 5, 2021).
[0034] Ginsenosides were determined according to the method described in “Colorimetric Determination of Ginsenosides in Ginseng” (Gui Shuangying et al., Journal of Anhui University of Traditional Chinese Medicine, Vol. 22, No. 4, August 2003).
[0035] Hyperoside was determined according to the method described in "Study on the Extraction Method and Content Determination of Hyperoside in Traditional Chinese Medicine Cuscuta Semen" (Gao Haiyan, Anti-Infective Pharmacology).
[0036] Oleanolic acid was determined according to the method described in "HPLC-ELSD method for determining the contents of oleanolic acid and ursolic acid in Ligustrum lucidum fruits from different origins" (Li Tao, Hao Wuchang, etc.).
[0037] Atractylodesin was determined according to the method described in “RP-HPLC method for simultaneous determination of atractylodesin and atractylodes lactone II in Atractylodes lancea” (Nanyang et al., Journal of Pharmaceutical Analysis, 2010).
[0038] The Chinese medicine composition J1 for controlling blood sugar by reducing sugar and clearing turbidity is prepared into tablets, capsules and other pharmaceutically acceptable dosage forms according to relevant pharmaceutical preparation methods in combination with appropriate auxiliary materials.
[0039] Embodiments 2 to 5 Preparation method of a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar
[0040] Examples 2 to 5 are respectively methods for preparing a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar. The steps are basically the same as those in Example 1, and the only difference is the amount of raw materials and process parameters. See Table 1 for details:
[0041] Table 1 List of process parameters in Examples 2 to 5
[0042]
[0043]
[0044] The other parts of Examples 2 to 5 are the same as those of Example 1 and will not be described again.
[0045] Example 6 Preparation method of a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar
[0046] This embodiment is a method for preparing a Chinese medicine composition for reducing blood sugar and clearing turbidity to control blood sugar, and the specific preparation process includes the following steps:
[0047] 1) Extraction
[0048] 11) Mix 0.1 mol / L citric acid and 0.1 mol / L sodium citrate in a volume ratio of 8.2:11.8 to obtain a citric acid buffer solution with a pH of 5.0.
[0049] Take eight medicinal materials, including 35kg of Astragalus, 12kg of Ginseng, 20kg of Polygonatum, 15kg of Ligustrum lucidum, 15kg of Cuscuta australis, 20kg of Lycium barbarum, 12kg of Atractylodes lancea and 12kg of Pueraria, add 10 times the total weight of citric acid buffer with a pH of 5.0 (i.e., 141kg of citric acid buffer with a pH of 5.0), then add 2.0wt% of the total weight of the eight medicinal materials, consisting of a complex enzyme consisting of cellulase, pectinase and papain in a weight ratio of 1:1:1, perform enzymolysis at 45°C for 1h, boil to inactivate the enzyme, filter, and obtain the eight medicinal liquids.
[0050] 12) Take 25 kg of Radix Rehmanniae, 25 kg of Rhizoma Dioscoreae and 12 kg of Rhizoma Cyperi, add 10 times the total weight of the three herbs in water, decoct twice (i.e., decoct twice with 62 kg of water), each time for 1 hour, filter, and combine the filtrate to obtain the three herbs liquid.
[0051] 2) Preparation
[0052] After the eight medicinal liquids were mixed with the three medicinal liquids, 6 kg of dextrin was added to the obtained medicinal liquid, stirred and mixed, concentrated, spray-dried, and dry granulated to obtain 37.4 kg of a Chinese medicine composition for lowering blood sugar, removing turbidity, and controlling blood sugar, with a total extraction rate of 15.47%, marked as J6.
[0053] The Chinese medicine composition J6 for lowering blood sugar, removing turbidity and controlling blood sugar contains 0.292 g / kg of astragaloside IV, 12.577 g / kg of total ginsenosides of Panax notoginseng, 0.054 g / kg of hyperoside, 0.244 g / kg of oleanolic acid and 0.338 g / kg of atractylodesin.
[0054] The Chinese medicine composition J6 for controlling blood sugar by reducing sugar and clearing turbidity is prepared into tablets, capsules and other pharmaceutically acceptable dosage forms according to relevant pharmaceutical preparation methods in combination with appropriate auxiliary materials.
[0055] It can be seen that the extraction rate and the effective ingredient retention of the Chinese medicine composition J6 for lowering blood sugar and removing turbidity for controlling blood sugar prepared in this example are significantly higher than those of the Chinese medicine composition J1 for lowering blood sugar and removing turbidity for controlling blood sugar prepared in Example 1.
[0056] Embodiments 7 to 10 Preparation method of a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar
[0057] Examples 7 to 10 are respectively methods for preparing a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar. The steps are basically the same as those in Example 1, and the only difference is the amount of raw materials and process parameters. See Table 2 for details:
[0058] Table 2 List of process parameters in Examples 7 to 10
[0059]
[0060]
[0061] The other parts of Examples 7 to 10 are the same as those of Example 1 and will not be described again here.
[0062] It should be noted that the content of effective ingredients such as astragaloside IV contained in the Chinese herbal composition for lowering blood sugar, removing turbidity and controlling blood sugar is affected by the dosage of corresponding Chinese herbal medicines and the total extraction rate.
[0063] Experimental Example 1 Acute toxicity test
[0064] The cooperative unit was commissioned to conduct acute toxicity experiments on mice on the Chinese medicine compositions J1 and J6 for reducing blood sugar and removing turbidity and controlling blood sugar prepared in Examples 1 and 6, as follows:
[0065] Twenty ICR mice weighing 18-22 g were divided into two groups, each with 10 mice, half of which were male and half were female. After fasting for 16 hours, they were gavaged with the Chinese herbal composition J1 for lowering blood sugar and turbidity to control blood sugar or the Chinese herbal composition J6 for lowering blood sugar and turbidity to control blood sugar, respectively, with a gavage dose of 60 mg / (g·BW). They were fed 4 hours after the last gavage, and the poisoning symptoms, number of deaths and time of death of the mice were observed and recorded in detail. The observation period was 14 days, and it was observed that no poisoning symptoms and no deaths occurred in the two groups of mice.
[0066] Therefore, the maximum tolerated acute oral dose of mice is greater than 60 g / (kg·BW), and the Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar prepared by the present invention is non-toxic to mice in acute oral toxicity.
[0067] Experimental Example 2 Pharmacodynamics Test
[0068] The cooperative unit was commissioned to conduct a hypoglycemic pharmacodynamic experiment on rats on the Chinese medicine compositions J1 and J6 for reducing blood sugar and clearing turbidity and controlling blood sugar prepared in Example 1 and Example 6, as follows:
[0069] 40 male SD rats weighing 180-200g were randomly divided into 4 groups after adaptive feeding for 2 weeks, namely normal control group, blank control group, experimental group 1 and experimental group 2 for model construction. The model construction method is as follows: the blank control group, experimental group 1 and experimental group 2 were all fed with high-sugar and high-fat feed (lard 10wt%, egg yolk powder 5wt%, sucrose 20wt%, cholesterol 2.0wt%, bile salt 1wt% and conventional feed 62wt%), and experimental group 1 and experimental group 2 were also given 10mg / (g·BW) of the Chinese medicine composition J1 for reducing blood sugar and turbidity and controlling blood sugar (corresponding to experimental group 1) or the Chinese medicine composition J6 for reducing blood sugar and turbidity and controlling blood sugar (corresponding to experimental group 2) daily, the normal control group was fed with conventional feed, and each group had free drinking water for 30 days.
[0070] The body weight, fasting blood glucose and insulin levels of rats were measured before and after the model was established. The specific results are as follows:
[0071] Table 3 List of changes in various parameters of rats (x±s, n=10)
[0072]
[0073]
[0074] It can be seen from the above table that the Chinese medicine composition for lowering blood sugar and removing turbidity for controlling blood sugar prepared by the present invention has an obvious blood sugar lowering effect, among which the Chinese medicine composition for lowering blood sugar and removing turbidity for controlling blood sugar J6 has a more obvious blood sugar lowering effect, which can reduce the blood sugar of rats to a normal level.
[0075] Experimental Example 3 Clinical Case
[0076] The cooperative outpatient clinic was commissioned to conduct follow-up treatment on 86 patients. All of the 86 patients were type 2 diabetes patients admitted to the outpatient clinic from August to September 2020. They were randomly divided into a control group, an observation group 1, and an observation group 2. Among them, there were 28 cases in the control group, including 8 males and 20 females, aged 24 to 60 years old, with a course of 2 to 27 months; there were 29 cases in the observation group 1, including 8 males and 21 females, aged 22 to 62 years old, with a course of 2 to 28 months; there were 29 cases in the observation group 2, including 8 males and 21 females, aged 23 to 61 years old, with a course of 2 to 27 months. There was no statistically significant difference in the general data of the three groups (P>0.05), and they were comparable. During the treatment, the control group took 0.25g of dimethoate tablets orally, 2 tablets each time, 3 times a day; the observation group took oral Chinese medicine composition J1 for lowering blood sugar and clearing turbidity to control blood sugar, 30g per day, 3 times a day; the observation group took oral Chinese medicine composition J2 for lowering blood sugar and clearing turbidity to control blood sugar, 30g per day, 3 times a day. Referring to the "Guidelines for Clinical Research of New Chinese Medicines", the TCM symptoms and blood sugar values of type 2 diabetes before and after treatment were observed and compared. The specific treatment results are as follows:
[0077] Table 4 Treatment results list
[0078]
[0079] It can be seen from Table 4 that the Chinese medicine composition for lowering blood sugar and removing turbidity for controlling blood sugar prepared by the present invention has a good therapeutic effect on diabetic patients, among which the Chinese medicine composition for lowering blood sugar and removing turbidity for controlling blood sugar J6 has a more obvious therapeutic effect, and the effective rate can reach 100%.
[0080] Typical cases:
[0081] Case 1: Hu XX, male, 32 years old, farmer, the patient had no obvious cause three years ago, and developed polydipsia, polyuria, fatigue, night sweats, accompanied by sexual dysfunction, fat and tender tongue with tooth marks, sunken spleen and stomach area, thin white fur, and deep, slow, stringy and thin pulse. Outpatient examination showed fasting blood sugar of 165mg, urine sugar (++++); Western medicine diagnosed diabetes; non-insulin dependent. After taking the Chinese medicine composition J1 for lowering sugar and turbidity to control blood sugar for half a month, the symptoms basically disappeared, blood sugar dropped to 110mg, and all symptoms basically disappeared. After taking it for more than three months, the blood sugar was maintained between 95 and 110mg, urine sugar (-), and all other indicators were within the normal range. Doctor's advice: Adhere to taking the Chinese medicine composition J1 for lowering sugar and turbidity to control blood sugar for more than half a year, and there was no recurrence in the follow-up for 2 years.
[0082] Case 2: Cai XX, female, 48 years old, worker, the patient had thirst and polydipsia, frequent urination, polyphagia and hunger one year ago, and was thinner than before. The outpatient examination showed fasting blood sugar of 220mg and urine sugar (++++), and was diagnosed as diabetes by Western medicine. After taking Western medicine for half a year in the outpatient clinic, the symptoms of polydipsia, polyphagia, and polyuria were alleviated, but the blood sugar was still unstable and increased after stopping the medication. And fatigue, spontaneous sweating, laziness, palpitations and shortness of breath appeared, tongue with tooth marks and cracks, and pulse was tight and thin. Diagnosed as diabetes by Western medicine. After taking the Chinese medicine composition J6 for lowering blood sugar and turbidity to control blood sugar for one month, the symptoms basically disappeared; continued to take the medicine for one month, all symptoms disappeared, 24h urine sugar quantitative 0~8, urine sugar qualitative (-), blood sugar dropped to 105mg, and all symptoms basically disappeared. Adhere to taking it for more than three months and re-examination: blood sugar is maintained between 90~110mg, urine sugar (-), and other indicators are within the normal range. Doctor's advice: Keep taking the Chinese medicine composition J6 for lowering blood sugar and clearing turbidity to control blood sugar, and consolidate.
[0083] Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
Claims
1. A method for preparing a Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar, characterized in that: The raw materials for preparing the Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar are as follows: 25-35 parts of Astragalus, 10-15 parts of Ginseng, 20-25 parts of Dioscorea opposita, 18-20 parts of Polygonatum, 20-25 parts of Rehmannia root, 12-15 parts of Ligustrum lucidum, 12-15 parts of Cuscuta, 15-20 parts of Lycium barbarum, 10-12 parts of Atractylodes, 12-15 parts of Cyperus rotundus and 10-15 parts of Pueraria root; The preparation method comprises the following steps: 1) Take eight medicinal materials, including astragalus, ginseng, polygonatum, glossy privet, dodder, wolfberry, atractylodes and kudzu root, add them to a citric acid buffer with a pH value of 5-5.6, add a complex enzyme consisting of cellulase, pectinase and papain in a weight ratio of 1:0.9-1.1:0.9-1.1, perform enzymolysis at 40-45℃ for 0.5-1h, boil to inactivate the enzyme, filter and obtain the eight medicinal liquids; The dosage of the citric acid buffer is 8 to 10 times the total weight of the eight medicinal materials; The dosage of the complex enzyme is 1.8-2.0wt% of the total weight of the eight medicinal materials; Take three herbs, namely, Radix Rehmanniae, Rhizoma Dioscoreae and Rhizoma Cyperi, add water to boil and extract, filter and obtain three herbs liquid; The amount of water used is 8 to 10 times the total weight of the three medicinal materials; 2) After the eight medicinal liquids are mixed with the three medicinal liquids, they are concentrated and dried to obtain the Chinese medicine composition for lowering blood sugar, removing turbidity and controlling blood sugar.
2. The method for preparing the Chinese medicine composition for reducing blood sugar and removing turbidity to control blood sugar according to claim 1, characterized in that: In step 2), after the eight medicinal liquids are mixed with the three medicinal liquids, dextrin needs to be added and mixed before the obtained medicinal liquid is concentrated.
3. The method for preparing the Chinese medicine composition for reducing blood sugar, removing turbidity and controlling blood sugar according to claim 2, characterized in that: The added amount of the dextrin is 5 to 8 parts by weight.
Citation Information
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