A high-efficiency cryoablation needle and an intelligent control low-temperature biopsy device

Abstract

This application relates to a high-efficiency cryoablation needle and an intelligent control cryogenic biopsy device. By replacing the attached probe with a coiled cryoablation needle, the refrigerant can directly pass through the coil inside the needle tube and freeze the cryocapsule at the end of the coil. The immediately frozen cryocapsule can continuously freeze the needle tip, allowing the needle tip to immediately form a cryogenic environment for cryogenic ablation without the need for pre-cooling. The refrigerant passes through the bulbous structure at the end of the coil, freezing the cryocapsule. The surface of the bulbous structure cools rapidly; essentially, the refrigerant enters from the refrigerant inlet pipe and exits from the refrigerant outlet pipe, cooling immediately within 0.05 seconds. In use, the refrigerant of the intelligent control cryogenic biopsy device enters the coil after passing through its valve assembly and is cooled by the elliptical bulbous structure of the coil, allowing for immediate ablation without waiting.

Description

Technical Field

[0001] This application relates to the field of intelligent medical device technology, and in particular to a high-efficiency cryoablation needle and an intelligent control low-temperature biopsy device. Background Technology

[0002] Low-temperature biopsy needles can be used as cryoablation needles in ablation procedures because the surgical stages involved in both low-temperature biopsy and cryoablation are roughly the same, requiring the use of low-temperature probes to freeze target cells before processing.

[0003] Among existing biopsy techniques, the use of cryoablation needles to sample lesions is a relatively common method. For example, in application number 2022100415555, the applicant provides an intelligent controlled cryoablation device. This device integrates the sampling needle as a separate consumable, with the cut biopsy instrument mounted on the outer shell via a mounting cavity. This allows for easy replacement of the biopsy needle, and when multiple lesions need to be biopsied, there is no need to repeatedly disassemble and reassemble the shell, probe, and cutting cannula, saving time and simplifying operation for medical personnel.

[0004] As can be seen from the accompanying drawings in the aforementioned patent, the cutting cannula and the high-efficiency cryoablation needle of the biopsy instrument under this technology need to be re-frozen before they can be extracted from the biopsy instrument for biopsy work. In other words, the high-efficiency cryoablation needle needs to be pre-cooled at low temperature in the biopsy instrument for a period of time before it can be used. The valve group is activated to push the high-efficiency cryoablation needle out of the biopsy instrument part and insert it into the subcutaneous tissue for biopsy.

[0005] Cryoablation, on the other hand, does not require a long pre-cooling period. With the appropriate choice of cooling medium, the gas path can be opened directly without waiting for pre-cooling, allowing for puncture and ablation procedures. Therefore, using this intelligent controlled low-temperature biopsy device for cryoablation would affect the ablation speed. Summary of the Invention

[0006] In view of this, this application proposes a high-efficiency cryoablation needle and an intelligent control low-temperature biopsy device. By designing a fast-response low-temperature ablation needle, the device directly circulates refrigerant to cool the needle and can be used immediately for ablation surgery, thereby improving the ablation speed.

[0007] This application proposes a high-efficiency cryoablation needle, comprising:

[0008] syringe;

[0009] A coil is disposed inside the needle tube;

[0010] A cryocapsule is provided at the end of the coil, and the cryocapsule is close to the needle of the needle tube;

[0011] The coil includes a refrigerant inlet pipe and a refrigerant outlet pipe. The refrigerant enters through the refrigerant inlet pipe, passes through the freezing chamber, and is discharged through the refrigerant outlet pipe. The needle of the needle tube is frozen through the freezing chamber and can then enter for cryoablation.

[0012] This application also proposes an intelligent control cryogenic biopsy device, including a housing, a valve assembly, a canister, and a compressed gas canister. The compressed gas canister is fitted inside the canister. The canister and the valve assembly are both fixed to the housing and connected to each other via an airflow channel. The valve assembly includes a main valve, a forward valve, and a retraction valve. The device also includes:

[0013] The mounting cavity is provided on the outer shell;

[0014] The biopsy instrument is fixed in the mounting cavity and is equipped with a matching cutting sleeve and a high-efficiency cryoablation needle.

[0015] A valve is provided on the housing, through which cryogenic compressed gas is guided into the valve assembly;

[0016] An intelligent robot is positioned on one side of the outer shell and holds the shell with a robotic arm. Under the control of a computer control system, it enables automated biopsy sampling.

[0017] As an optional implementation of this application, it may also include:

[0018] The air inlet is located at the right end of the outer shell and is connected to the piston cylinder of the biopsy instrument through a pipeline, providing air power to drive the movement of the cutting sleeve;

[0019] An air inlet is provided on the biopsy instrument, through which the coolant supplied by the coolant supply pipeline system is guided into the high-efficiency cryoablation needle;

[0020] The first air intake pipe is connected between the valve and the air intake port;

[0021] A second air intake pipe is connected between the valve and the air intake end.

[0022] As an optional implementation of this application, it may also include:

[0023] An airflow chamber is located within the valve assembly and communicates with the tank cylinder;

[0024] A gas tube connects the outlet of the airflow chamber to the valve, and when the outlet of the airflow chamber is opened, it guides cooling gas to the valve;

[0025] The pneumatic system, located within the valve group, supplies gas through valves and guides the low-temperature compressed gas to the main valve, forward valve, retraction valve, and the high-efficiency cryoablation needle, respectively.

[0026] As an optional implementation of this application, it may also include a valve opening and closing mechanism, comprising:

[0027] A spring is fitted inside the airflow cavity;

[0028] A threaded pair fits into the valve assembly on one side of the airflow chamber;

[0029] The valve screw is confined within the airflow chamber by the spring;

[0030] The motor drive system is fixed to the housing, and the valve screw is driven by the motor drive system.

[0031] As an optional embodiment of this application, the valve screw may optionally include:

[0032] The valve block, constrained by the spring at its right end inside the airflow chamber, seals off the outlet of the airflow chamber.

[0033] The transmission screw is horizontally fixed on the valve block, and its right end passes through the threaded pair and extends out of the valve group to connect with the output end of the motor drive system.

[0034] The motor drive system drives the transmission screw to move, pushing the valve block to open or close the outlet of the airflow chamber.

[0035] As an optional implementation of this application, it may also include:

[0036] The tank head fits into the top of the tank cylinder and elastically restricts the compressed gas tank;

[0037] A piercing pin connector is disposed within the airflow channel, and the gas outlet of the compressed gas tank is fitted onto the piercing pin connector;

[0038] When the compressed gas canister is fitted inside the cylinder, the compressed gas is released into the airflow chamber of the valve assembly through the airflow channel by piercing the gas outlet of the compressed gas canister through the piercing pin connector.

[0039] As an optional implementation of this application, it may also include:

[0040] An air vent is provided on the biopsy instrument, and the airflow from the piston cylinder of the biopsy instrument is sent to the gas circulation system for circulation through a pipeline.

[0041] As an optional implementation of this application, it may also include:

[0042] Tissue markers are placed at the location of the lesion to mark its location;

[0043] A delivery needle is used to deliver the tissue marker to the lesion site and remove the tissue marker after the biopsy is completed.

[0044] As an optional implementation of this application, it may also include:

[0045] An imaging system, located on one side of the intelligent robot, is used to perform imaging on the marked lesion tissue, acquire images of the lesion location in real time, and send them to the computer control system.

[0046] A display, located on one side of the intelligent robot, is used to receive and display imaging images;

[0047] The imaging system and the monitor are electrically connected to the computer control system.

[0048] As an optional implementation of this application, it may also include:

[0049] A cutting head, located at the end of the cutting sleeve, is used for rotary cutting sampling; the cutting head contains at least three rotary cutting blades.

[0050] Technical effects of this application:

[0051] This solution replaces the attached probe with a coiled cryoablation needle in the provided intelligent controlled cryobiopsy device. The refrigerant flows directly through the coil inside the needle, freezing the cryocapsule at the end of the coil. The rapidly frozen cryocapsule continuously freezes the needle, creating an immediate cryogenic environment for cryoablation without the need for pre-cooling. The refrigerant passes through the balloon structure at the end of the coil, rapidly cooling the cryocapsule. Essentially, the refrigerant enters through the refrigerant inlet and exits through the refrigerant outlet, cooling almost instantly, within 0.05 seconds. The elliptical balloon structure has a larger surface area, increasing the cryogenic freezing area, and most importantly, the elliptical shape facilitates needle insertion. In use, the refrigerant from the intelligent controlled cryobiopsy device enters the coil after passing through its valve assembly and is cooled by the elliptical balloon structure, allowing for immediate ablation surgery without waiting. Attached Figure Description

[0052] The accompanying drawings, which are included in and form part of this specification, illustrate exemplary embodiments, features, and aspects of this application together with the specification and serve to explain the principles of this application.

[0053] Figure 1This diagram shows a cross-sectional view of the biopsy device installed as a separate consumable in this application.

[0054] Figure 2 This diagram shows a cross-sectional view of the biopsy device without its separate consumable component.

[0055] Figure 3 This application is shown Figure 2 A three-dimensional structural diagram;

[0056] Figure 4 This diagram shows a front view of the biopsy device as a separate consumable according to this application.

[0057] Figure 5 This diagram shows the system composition of the intelligent control low-temperature biopsy device of this application;

[0058] Figure 6 A schematic diagram showing the organization mark of this application;

[0059] Figure 7 This diagram illustrates the structure of the high-efficiency cryoablation needle of this application.

[0060] Figure 8 This diagram shows a cross-sectional view of the cryocapsule of this application. Detailed Implementation

[0061] Various exemplary embodiments, features, and aspects of this application will now be described in detail with reference to the accompanying drawings. The same reference numerals in the drawings denote elements that have the same or similar functions. Although various aspects of the embodiments are shown in the drawings, they are not necessarily drawn to scale unless specifically indicated otherwise.

[0062] It should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the present invention or simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the present invention.

[0063] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0064] The term “exemplary” as used herein means “serving as an example, embodiment, or illustration.” Any embodiment illustrated herein as “exemplary” is not necessarily to be construed as superior to or better than other embodiments.

[0065] Furthermore, to better illustrate this application, numerous specific details are provided in the following detailed embodiments. Those skilled in the art should understand that this application can be implemented without certain specific details. In some instances, methods, means, components, and circuits well-known to those skilled in the art have not been described in detail in order to highlight the main points of this application.

[0066] like Figure 7 As shown, a high-efficiency cryoablation needle includes:

[0067] 100 syringes;

[0068] A coil 200 is disposed within the needle tube 100;

[0069] A cryocapsule is provided at the end of the coil 200, and the cryocapsule is close to the needle of the needle tube 100;

[0070] The coil 200 includes a refrigerant inlet pipe 300 and a refrigerant outlet pipe 400. The refrigerant enters through the refrigerant inlet pipe 300, passes through the cryo-bag, and is discharged through the refrigerant outlet pipe 400. The needle of the needle tube 100 is frozen by the cryo-bag and can then enter for cryoablation.

[0071] In the intelligent control low-temperature biopsy device provided in application number 2022100415555, this application uses the coil cryoablation needle of this design to replace its attached probe. The refrigerant can pass directly through the coil 200 inside the needle tube 100 and freeze the cryocapsule at the end of the coil 200. The cryocapsule, which is frozen in time, can continuously freeze the needle, so that the needle can immediately form a low-temperature environment for low-temperature ablation, without the need for pre-cooling.

[0072] The coil 200 is a miniature stainless steel low-temperature resistant tube. Part of the tubing is coiled, which improves cooling efficiency and allows the refrigerant to circulate within the syringe 100 for an extended period. Figure 7 As shown, a freezing bladder is provided at the end of the coil 200. The freezing bladder can increase the freezing area. The end of the coil 200 can be integrally formed or have a freezing bladder structure installed separately.

[0073] Note that the cryocapsule here is not an open structure, but a hollow spherical structure. Figure 8As shown, this embodiment uses an elliptical spherical structure with internal gaps. The refrigerant inlet pipe 300 and the refrigerant outlet pipe 400 are divided into an air inlet and an air outlet connecting the elliptical spherical structure.

[0074] During installation, simply insert the elliptical balloon structure into the tail of the needle tube 100.

[0075] The refrigerant passes through the bulbous structure at the end of coil 200 and freezes the cryo-bag at low temperature. The surface of the bulbous structure cools down rapidly. Basically, the refrigerant enters from refrigerant inlet pipe 300 and exits from refrigerant outlet pipe 400, cooling immediately, in less than 0.05 seconds.

[0076] The elliptical balloon structure has a larger surface area, which can increase the cryogenic freezing area. Most importantly, the elliptical structure makes it easier to insert a needle tube 100.

[0077] When in use, the refrigerant of the intelligent control low-temperature biopsy device enters the coil 200 after passing through its valve group, and is cooled by the elliptical balloon structure of the coil 200, so it can be used immediately for ablation surgery without waiting.

[0078] The following is a description of using the high-efficiency cryoablation needle of this design on the intelligent control low-temperature biopsy device with application number 2022100415555. The disclosed technology will not be repeated in this embodiment.

[0079] like Figure 1 As shown in the figure, this application proposes an intelligent control cryogenic biopsy device, including a housing 1, a valve group 15, a canister 5 and a compressed air canister 18. The compressed air canister 18 is fitted inside the canister 5. The canister and the valve group 15 are both fixed on the housing and are connected to each other through an airflow channel. The valve group 15 includes a main valve, a forward valve and a retraction valve.

[0080] In this embodiment, the housing containing the canister 5 and the valve assembly 15 are an integral structure connected to each other. A piercing pin connector 4 is installed at the bottom of the canister 5. When the compressed gas canister 18 is fitted inside the canister 5, the piercing pin connector 4 pierces the gas outlet of the compressed gas canister, releasing the compressed gas through the airflow channel into the airflow chamber 11 of the valve assembly 15. When the valve screw sealing the outlet of the airflow chamber is opened by the motor drive system, the cryogenic compressed gas flows into the valve and then flows to different control valve bodies. The valve assembly 15 includes a main valve, a forward valve, and a retraction valve. For its specific structure and corresponding pneumatic system, please refer to the embodiment described in patent publication CN100571649C, which will not be repeated here.

[0081] As an optional implementation of this application, it may also include:

[0082] The tank end cap fits onto the top of the tank cylinder and elastically restricts the compressed gas tank; the tank end cap is used to tighten the compressed gas tank 18 inside the tank cylinder 5 when the compressed gas tank 18 is fitted inside the tank cylinder 5, so that the piercing pin connector 4 pierces the gas outlet of the compressed gas tank.

[0083] In this embodiment, the biopsy needle is installed as a separate consumable on the outer shell. Compared with the existing patented technology, this technology no longer requires disassembling the outer shell to assemble and replace the cutting sleeve and the high-efficiency cryoablation needle. Instead, a biopsy instrument is directly screwed onto the outer mounting position, and the gas path can be connected for working sampling.

[0084] like Figure 2 and 3 As shown, it also includes:

[0085] The mounting cavity is provided on the outer shell 1;

[0086] like Figure 2 As shown, the outer casing 1 of the sampling device of this application is a cylinder with an open left end and a tubular structure, and its right end gradually narrows. The valve assembly 15 is fixed on the upper outer surface of the casing and is integrally connected with the canister 5. An installation cavity with an open left end is provided on the outer side, and an external thread 2 is provided on the inner side of its left end for screwing on biopsy instruments.

[0087] The biopsy instrument 16 is fixed within the mounting cavity, and a matching cutting sleeve 17 and a high-efficiency cryoablation needle are disposed therein; Figure 4 The biopsy device shown is an independent consumable. Its body mates with the mounting cavity, and its head is a conical connector with internal threads for mating with the external thread 2 on the outer side of the left end of the mounting cavity. After installation, some cooling gas enters through pipe 3, and then connects to the piston cylinder inside the biopsy device through the air inlet, providing air power to drive the movement of the cutting sleeve. The coolant supplied by the coolant supply pipeline system is guided to the high-efficiency cryoablation needle through the air inlet hole on the biopsy device, and finally the gas is discharged through the exhaust hole on the biopsy device.

[0088] Valve 6 is located on the outer casing and is specifically fixedly installed on the outer side of the top of valve assembly 15. The valve guides the cryogenic compressed gas from the airflow chamber into the valve assembly. First, it enters the main valve, and then, driven by the cam of the motor drive system, it is controlled to enter the forward valve and the retraction valve respectively. After the compressed gas is output from the airflow chamber of valve assembly 15, it is guided to the valve through the pipeline. The valve is used for safety control. Under automatic control, the cryogenic cooling gas is guided to the main valve and then distributed. The cooling compressed gas circulates in the forward valve and the retraction valve according to the gas path setting, as described in the above patent embodiment.

[0089] like Figure 5 As shown, in addition to the low-temperature biopsy device composed of the above-mentioned components, this embodiment uses an intelligent robot instead of a human hand. The robot's robotic arm holds the outer shell 1 of the low-temperature biopsy device, and the movement of the low-temperature biopsy device can be controlled by the robotic arm to achieve precise movement for puncture biopsy.

[0090] An intelligent robot, positioned on one side of the outer casing, holds the casing with a robotic arm and performs automated biopsy sampling under the control of a computer control system. The model and type of the intelligent robot are not limited here, as long as it can hold or clamp the casing with its robotic arm, and then, through computer control, position and move the held biopsy instrument, allowing the probe to penetrate near the lesion tissue. Specific programming and spatial positioning are calculated comprehensively from the system data of the imaging system and the robot, and will not be further restricted or detailed here.

[0091] To further optimize the system, contrast imaging of the lesion tissue, such as color Doppler ultrasound, can be used to calculate the location of the lesion tissue to be biopsied. After conversion, the specific location coordinates can be obtained. The monitor can display the lesion location in real time during the biopsy process, facilitating direct observation of the procedure.

[0092] As an optional implementation of this application, it may also include:

[0093] The air inlet is located at the right end of the outer shell and is connected to the piston cylinder of the biopsy instrument through a pipeline, providing air power to drive the movement of the cutting sleeve;

[0094] An air inlet is provided on the biopsy instrument, through which the coolant supplied by the coolant supply pipeline system is guided into the high-efficiency cryoablation needle;

[0095] The first air intake pipe is connected between the valve and the air intake port;

[0096] A second air intake pipe is connected between the valve and the air intake end.

[0097] like Figure 1-3 As shown, the air inlet 10 is located at the right end of the outer casing 1 and is connected to the piston cylinder of the biopsy instrument 16 via a pipeline, providing aerodynamic power to drive the movement of the high-efficiency cryoablation needle. The incoming air is converted into the kinetic force of the lead screw through the piston cylinder, causing the gas in the lead screw to enter the piston cylinder 2 through the air inlet 10, thus driving the lead screw to move. The reciprocating motion of the lead screw can be achieved through airflow circulation. Further details are omitted here.

[0098] An air inlet 12 is provided on the biopsy instrument 16, and the coolant supplied by the coolant supply pipeline system is guided to the probe inside the biopsy instrument 16 through the pipeline.

[0099] A valve 6 is mounted on the valve assembly 15, with a first air inlet pipe 3 and a second air inlet pipe 7 connected in parallel thereon. The outlet of the first air inlet pipe 3 is connected to the housing 1 and communicates with the air inlet 12, providing cooling gas to the high-efficiency cryoablation needle 17. The second air inlet pipe 7 is connected to the air inlet 10, providing pneumatic gas to the high-efficiency cryoablation needle 17. The outlet of the valve assembly 15 is opened and closed by a screw driven by a motor. When open, gas passes through the air pipe 8 to the valve 6 and is distributed to the first air inlet pipe 3 and the second air inlet pipe 7. Each pipe has its own gas circulation system for cooling and guidance. The outlet of the first air inlet pipe 3 is connected to the housing 1 and communicates with the air inlet 12, providing cooling gas to the high-efficiency cryoablation needle 17. The second air inlet pipe 7 is connected to the air inlet 10, providing pneumatic gas to the high-efficiency cryoablation needle 17.

[0100] As an optional implementation of this application, it may also include:

[0101] An airflow chamber 11 is located within the valve assembly 15 and is connected to the tank cylinder 5;

[0102] Air pipe 8 is connected between the outlet of the airflow chamber and the valve. When the outlet of the airflow chamber is opened, cooling gas is guided to the valve.

[0103] The pneumatic system, located within the valve group, supplies gas through valves and guides the low-temperature compressed gas to the main valve, forward valve, retraction valve, and the high-efficiency cryoablation needle, respectively.

[0104] like Figure 1 As shown, when the compressed gas tank 18 is fitted inside the cylinder 5, the compressed gas is released into the airflow chamber 11 of the valve assembly 15 by piercing the gas outlet of the compressed gas tank 18 through the piercing pin connector 4.

[0105] After the valve opening and closing mechanism is opened, the cryogenic compressed gas flows from the airflow chamber 11 to the valve 6 through the air pipe 8, and then through the pneumatic system, the cryogenic compressed gas is guided to the main valve, the forward valve, the retraction valve, and the high-efficiency cryoablation needle. For details of the pneumatic system, please refer to the technical principles described in the embodiments of the prior art.

[0106] As an optional implementation of this application, it may also include a valve opening and closing mechanism, comprising:

[0107] A spring is fitted inside the airflow cavity;

[0108] Threaded pair 21 fits into the valve assembly on one side of the airflow chamber;

[0109] The valve screw is confined within the airflow chamber by the spring;

[0110] The motor drive system is fixed to the housing, and the valve screw is driven by the motor drive system.

[0111] In this application, a valve opening and closing mechanism is provided between the airflow chamber 11 and the valve assembly 15, and the valve is opened and closed by a screw system driven by an electric motor. Figure 1 and 2 As shown, a valve screw is installed inside the airflow chamber to open and close the air outlet at the right end of the airflow chamber. The valve screw is connected by a valve block 14 and a transmission screw 13, as detailed below.

[0112] To ensure the valve screw tightly seals the outlet, a spring fitted within the airflow chamber presses against the left end face of the valve screw, thus pressing the valve block 14 against the outlet. To disengage the valve block 14 and open the outlet, a servo-driven pneumatic system-operated transmission screw 13 pushes the valve block 14 out. The right end of the valve screw is a horizontally positioned transmission screw 13, connected to the output end 9 of the pneumatic system. Here, a nut pair converts the rotation of the output end 9 into linear motion. Within the valve assembly 15 on the right side of the outlet, a mounting cavity corresponding to the left and right airflow chambers is provided. A block-shaped threaded joint 21 is fixed within this cavity. The transmission screw 13 passes through the threaded joint 21 and extends out of the valve assembly 15, connecting to the output end 9 of the pneumatic system. After power-on, the pneumatic system starts, causing the output end 9 to drive the transmission screw 13. After conversion by the threaded pair 21, the transmission screw 13 drives the valve block 14 to move, thereby enabling the valve block 14 to open and close the airflow chamber to release cooling gas or liquid. The gas is then transported to the valve 6 for diversion through the air pipe 8.

[0113] As an optional embodiment of this application, the pneumatic system is optionally a servo drive system, including a computer control system, a battery, a motor and a gearbox. The battery is electrically connected to the computer control system and the motor respectively, the motor is connected to the gearbox, and the output end 9 is located on the gearbox and maintains uniform rotation.

[0114] As an optional embodiment of this application, the valve screw may optionally include:

[0115] The valve block, constrained by the spring at its right end inside the airflow chamber, seals off the outlet of the airflow chamber.

[0116] The transmission screw is horizontally fixed on the valve block, and its right end passes through the threaded pair and extends out of the valve group to connect with the output end of the motor drive system.

[0117] The motor drive system drives the transmission screw to move, pushing the valve block to open or close the outlet of the airflow chamber.

[0118] like Figure 3 As shown, the valve block 14 is a flexible cylindrical structure that can be sealed at the air outlet by a spring, and can be opened by the drive screw 13. The drive screw 13 passes through the threaded pair 21, and its left and right ends can be connected to the corresponding valve block 14 and the output end 9 of the motor drive system respectively by screwing, welding or integral molding. The motor drive system drives the drive screw to move, pushing open the valve block to open or close the outlet of the airflow chamber.

[0119] As an optional implementation of this application, it may also include:

[0120] An air outlet 12 is provided on the biopsy instrument, and airflow from the piston cylinder of the biopsy instrument is sent to the gas circulation system for circulation through a pipeline. When the rocket device 16 is installed in the mounting cavity, it is connected to the outlet end of the first air inlet pipe 3 through the air outlet 12, or through a pipeline, to provide cooling gas for the high-efficiency cryoablation needle 17.

[0121] In this application, in order to facilitate the localization and marking of lesion tissue and to provide target location data for intelligent robots, a tissue marker is input into the lesion tissue through a delivery needle in the imaging environment to spatially mark the location of the lesion tissue.

[0122] like Figure 6 As shown, as an optional embodiment of this application, it may also include:

[0123] A tissue marker, placed at the lesion site, is used to mark the location of the lesion. The tissue marker can be metallic Ti, which is easily detected by the imaging system, facilitating imaging and thus displaying the specific location of the lesion tissue. By placing the tissue marker, lesion repositioning can be avoided during later treatment. The marked location can be detected by imaging systems such as ultrasound, magnetic resonance imaging (MRI), or X-rays, allowing for targeted biopsy. A columnar tissue marker 101 with hooks on its outer surface is placed within the lesion 103 via a delivery needle 102. In this embodiment, the specific shape of the tissue marker is not limited.

[0124] A delivery needle is used to deliver the tissue marker to the lesion site and to remove the tissue marker after the biopsy. A delivery needle 102 is used, with the assistance of the biopsy data visualization system, to deliver the tissue marker 101 from the biopsy data visualization system to the lesion site 103; and, after the biopsy, with the assistance of the biopsy data visualization system, to remove the tissue marker from the lesion site to the body surface. The specific type of delivery needle 102 is not limited here.

[0125] The material of the delivery needle or the tip of the delivery needle is the material that is imaged under the imaging system of the biopsy data visualization system. Preferably, it is Ti.

[0126] As an optional implementation of this application, it may also include:

[0127] An imaging system, located on one side of the intelligent robot, performs imaging on the marked lesion tissue, acquiring real-time images of the lesion location and sending them to the computer control system. The imaging system is used to image the lesion tissue, acquiring real-time images of the lesion location and biopsy sampling images, and sending them to the computer control system. The imaging system is mainly used to visualize tissue markers in the lesion tissue. After processing by the computer control system, the visualized images are sent to a monitor for real-time display, allowing doctors to easily identify the location of the lesion tissue. Furthermore, the imaging system also visualizes multiple steps in the process, including the placement of the delivery needle on the tissue marker, and the cutting cannula and probe used in the biopsy. Therefore, the tip of the cutting cannula and the puncture segment of the high-efficiency cryoablation needle need to be made of a special material that can be identified by imaging. In this embodiment, titanium is preferred. This allows the imaging system to perform imaging before and after the biopsy, achieving visualized biopsy operation, facilitating doctors to identify the location and perform accurate biopsies.

[0128] A display, located on one side of the intelligent robot, is used to receive and display imaging images;

[0129] The imaging system and the monitor are electrically connected to the computer control system. The monitor receives and displays the images processed by the computer control system, showing the biopsy process in real time.

[0130] As an optional implementation of this application, it may also include:

[0131] A cutting head, located at the end of the cutting sleeve, is used for rotary cutting sampling; the cutting head contains at least three rotary cutting blades.

[0132] As in Figure 4 The enlarged schematic diagram of the end structure of the cutting head shows that the cutting head has multiple rotary cutting blades, which are used for forward and rotary cutting under the drive of the valve body. The rotary cutting blades at the head are used to cut and sample the lesion tissue fixed by the probe, and the sample can be retrieved after sampling. Here, three centrally symmetrical rotary cutting blades are preferred for rotary cutting and sampling.

[0133] This embodiment is an example of sampling lesion tissue, but it can also be applied to sampling other sites or even non-lesion tissues, simply by changing the sampling environment and corresponding parameters.

[0134] The various embodiments of this application have been described above. These descriptions are exemplary and not exhaustive, nor are they limited to the disclosed embodiments. Many modifications and variations will be apparent to those skilled in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen to best explain the principles, practical application, or improvement of the technology in the market, or to enable others skilled in the art to understand the embodiments disclosed herein.

Claims

1. A high-efficiency cryoablation needle, characterized in that, include: syringe; A coil is disposed inside the needle tube; The end of the coil is provided with a cryocapsule, which is close to the needle tip of the needle tube. The cryocapsule is an elliptical hollow spherical structure. The coil includes a refrigerant inlet pipe and a refrigerant outlet pipe. The refrigerant enters through the refrigerant inlet pipe, passes through the freezing chamber, and is discharged through the refrigerant outlet pipe. The needle of the needle tube is frozen through the freezing chamber and can then enter for cryoablation.

2. An intelligent control cryogenic biopsy device for cryoablation, comprising a shell, a valve assembly, a canister, and a compressed gas canister, wherein the compressed gas canister is fitted inside the canister, the canister and the valve assembly are both fixed to the shell and connected to each other via an airflow channel, the valve assembly comprising a main valve, a forward valve, and a retraction valve, characterized in that, Also includes: The high-efficiency cryoablation needle as described in claim 1; The mounting cavity is provided on the outer shell; The biopsy instrument is fixed in the mounting cavity and is equipped with a matching cutting sleeve and a high-efficiency cryoablation needle. A valve is provided on the housing, through which cryogenic compressed gas is guided into the valve assembly; An intelligent robot is positioned on one side of the outer shell and holds the outer shell with a robotic arm. Under the control of a computer control system, it realizes automated biopsy sampling. The air inlet is located at the right end of the outer shell and is connected to the piston cylinder of the biopsy instrument through a pipeline, providing air power to drive the movement of the cutting sleeve; An air inlet is provided on the biopsy instrument, through which the coolant supplied by the coolant supply pipeline system is guided into the high-efficiency cryoablation needle; The first air intake pipe is connected between the valve and the air intake port; A second air intake pipe is connected between the valve and the air intake end.

3. The intelligent control low-temperature biopsy device according to claim 2, characterized in that, Also includes: An airflow chamber is located within the valve assembly and communicates with the tank cylinder; A gas tube connects the outlet of the airflow chamber to the valve, and when the outlet of the airflow chamber is opened, it guides cooling gas to the valve; The pneumatic system, located within the valve group, supplies gas through valves and guides the low-temperature compressed gas to the main valve, forward valve, retraction valve, and the high-efficiency cryoablation needle, respectively.

4. The intelligent control low-temperature biopsy device according to claim 3, characterized in that, It also includes the valve opening and closing mechanism, including: A spring is fitted inside the airflow cavity; A threaded pair fits into the valve assembly on one side of the airflow chamber; The valve screw is confined within the airflow chamber by the spring; The motor drive system is fixed to the housing, and the valve screw is driven by the motor drive system.

5. The intelligent control low-temperature biopsy device according to claim 4, characterized in that, The valve screw includes: The valve block, constrained by the spring at its right end inside the airflow chamber, seals off the outlet of the airflow chamber. The transmission screw is horizontally fixed on the valve block, and its right end passes through the threaded pair and extends out of the valve group to connect with the output end of the motor drive system. The motor drive system drives the transmission screw to move, pushing the valve block to open or close the outlet of the airflow chamber.

6. The intelligent control cryogenic biopsy device according to claim 4 or 5, characterized in that, Also includes: The tank head fits into the top of the tank cylinder and elastically restricts the compressed gas tank; A piercing pin connector is disposed within the airflow channel, and the gas outlet of the compressed gas tank is fitted onto the piercing pin connector; When the compressed gas canister is fitted inside the cylinder, the compressed gas is released into the airflow chamber of the valve assembly through the airflow channel by piercing the gas outlet of the compressed gas canister through the piercing pin connector.

7. The intelligent control low-temperature biopsy device according to claim 2, characterized in that, Also includes: An air vent is provided on the biopsy instrument, and the airflow from the piston cylinder of the biopsy instrument is sent to the gas circulation system for circulation through a pipeline.

8. The intelligent control low-temperature biopsy device according to any one of claims 2-7, characterized in that, Also includes: Tissue markers are placed at the location of the lesion to mark its location; A delivery needle is used to deliver the tissue marker to the lesion site and remove the tissue marker after the biopsy is completed.

9. The intelligent control low-temperature biopsy device according to claim 8, characterized in that, Also includes: An imaging system, located on one side of the intelligent robot, is used to perform imaging on the marked lesion tissue, acquire images of the lesion location in real time, and send them to the computer control system. A display, located on one side of the intelligent robot, is used to receive and display imaging images; The imaging system and the monitor are electrically connected to the computer control system.

10. The intelligent control cryogenic biopsy device according to claim 2 or 9, characterized in that, Also includes: A cutting head, located at the end of the cutting sleeve, is used for rotary cutting sampling; the cutting head contains at least three rotary cutting blades.

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