Biosignal processing system, biosignal processing method and electronic device

Abstract

The present application proposes a biological signal processing system, a biological signal processing method and an electronic device. The system includes: an in-vivo module, including a signal acquisition unit, an amplitude modulation unit, and a first communication unit, wherein the amplitude modulation unit includes a local oscillator signal generating unit and a modulation unit; an in-vivo module, including a second communication unit, a signal demodulation unit and a signal processing unit. The present application modulates the original biological signal and transmits it to the outside of the body, demodulates the signal by a signal demodulation unit in the body, and then injects the signal output by the signal demodulation unit into the signal processing unit for processing, and then determines the biological body information. The present application places large-volume, high-power-consumption and heat-prone devices such as signal processing units outside the body, and the in-vivo module only retains the signal acquisition unit, the amplitude modulation unit and the first communication unit for collecting the original biological signal, which can reduce the volume of the in-vivo device, improve the user's comfort, and reduce the burden on the power supply of the in-vivo device.

Description

Technical Field

[0001] The present application relates to the technical field of original biological signal processing, and in particular to a biological signal processing system, a biological signal processing method and an electronic device. Background Art

[0002] With the development of medical technology, implantable biosignal acquisition devices are becoming more and more widely used because they can provide continuous, real-time and accurate physiological information and provide accurate data support for the management and diagnosis of various diseases.

[0003] Existing implantable biosignal acquisition devices often directly implant high-precision analog-to-digital converters and corresponding digital signal processors into the body to process biosignals directly in the body, which makes the body device larger in size. At the same time, the high-precision analog-to-digital converters and digital signal processors will generate heat during operation, which makes the user's comfort poor after the device is implanted in the user's body. At the same time, in order to reduce the size of the device, implantable biosignal acquisition devices often cannot be equipped with large-capacity batteries, and the high-precision analog-to-digital converters and digital signal processors have high energy consumption, which puts a heavy power burden on the implantable device. Summary of the Invention

[0004] The main purpose of the embodiments of the present application is to propose a biosignal processing system, a biosignal processing method and an electronic device, which can reduce the volume of the device implanted in the body, reduce the power consumption of the device implanted in the body, reduce the power supply burden, and improve the comfort of the user.

[0005] A first aspect of an embodiment of the present application provides a biological signal processing system, comprising:

[0006] An in-vivo module, comprising a signal acquisition unit, an amplitude modulation unit, and a first communication unit, wherein the signal acquisition unit is used to acquire original biological signals, the amplitude modulation unit includes a local oscillator signal generation unit and a modulation unit, the local oscillator signal generation unit is used to generate a local oscillator signal, and the local oscillator signal is used to modulate the original biological signals, the input end of the modulation unit is respectively connected to the signal acquisition unit and the local oscillator signal generation unit, and the output end of the modulation unit is connected to the first communication unit;

[0007] The in vitro module includes a second communication unit, a signal demodulation unit and a signal processing unit, wherein the second communication unit is communicatively connected to the first communication unit, the second communication unit is also connected to the input end of the signal demodulation unit, the output end of the signal demodulation unit is connected to the signal processing unit, and the signal processing unit is used to extract the original biological signal from the signal output by the signal demodulation unit and determine the biological body information based on the original biological signal.

[0008] In some embodiments, a verification signal unit is further connected between the signal acquisition unit and the modulation unit, and the verification signal unit includes a verification signal generation unit and an adder. The verification signal generation unit is used to generate a first verification signal, and the input end of the adder is respectively connected to the signal acquisition unit and the verification signal generation unit, and the output end of the adder is connected to the input end of the modulation unit.

[0009] In some embodiments, the first verification signal is a single-tone signal or a multi-tone signal with a preset frequency and a preset amplitude.

[0010] In some embodiments, the first communication unit and the second communication unit are both coils, and the first communication unit and the second communication unit communicate with each other through coil coupling.

[0011] In some embodiments, the signal acquisition unit includes at least one signal acquisition subunit, each of the signal acquisition subunits is connected to the input end of the adder, and the signal acquisition subunit is an electrode or a sensor.

[0012] In some embodiments, a multiplexer is provided between the signal acquisition subunit and the input end of the modulation unit.

[0013] A second aspect of the present application further provides a biological signal processing method, which is applied to the biological information processing system as described in any one of the embodiments of the first aspect, the method comprising:

[0014] Collecting original biological signals;

[0015] modulating the original biological signal to obtain a first biological signal;

[0016] transmitting the first biological signal to the second communication unit through the first communication unit;

[0017] demodulating the first biosignal to obtain a second biosignal;

[0018] Biological information is determined based on the second biological signal.

[0019] In some embodiments, before modulating the original biosignal to obtain the first biosignal, the method further includes:

[0020] Generate a first verification signal according to a preset frequency and a preset amplitude, wherein the first verification signal is a single-tone signal or a multi-tone signal;

[0021] The first verification signal is superimposed on the original biological signal to update the original biological signal.

[0022] In some embodiments, determining the biological information based on the second biological signal includes:

[0023] separating a second verification signal and a third biosignal from the second biosignal;

[0024] determining a distortion coefficient according to the first verification signal and the second verification signal;

[0025] restoring the third biosignal to the original biosignal according to the distortion coefficient;

[0026] The biological information is determined according to the original biological signal.

[0027] In some embodiments, determining the distortion coefficient according to the first verification signal and the second verification signal includes:

[0028] Performing a Fourier transform on the second verification signal to obtain a frequency and an amplitude of the second verification signal;

[0029] determining a frequency distortion coefficient according to the preset frequency and the frequency of the second verification signal;

[0030] An amplitude distortion coefficient is determined according to the preset amplitude and the amplitude of the second verification signal.

[0031] In some embodiments, restoring the third biosignal to the original biosignal according to the distortion coefficient includes:

[0032] Performing Fourier transform on the third biosignal to obtain the frequency and amplitude of the third biosignal;

[0033] determining the frequency of the original biosignal according to the frequency of the third biosignal and the frequency distortion coefficient;

[0034] The amplitude of the original biosignal is determined according to the amplitude of the third biosignal and the amplitude distortion coefficient.

[0035] A third aspect of the embodiments of the present application provides an electronic device, comprising a biological signal processing system as described in any one of the embodiments of the first aspect.

[0036] The embodiments of the present application provide a biological signal processing system, a biological signal processing method, and an electronic device. The biological signal processing system includes: an in-vivo module, including a signal acquisition unit, an amplitude modulation unit, and a first communication unit, wherein the signal acquisition unit is used to acquire original biological signals, the amplitude modulation unit includes a local oscillator signal generation unit and a modulation unit, the local oscillator signal generation unit is used to generate a local oscillator signal, and the local oscillator signal is used to modulate the original biological signals, the input end of the modulation unit is respectively connected to the signal acquisition unit and the local oscillator signal generation unit, and the output end of the modulation unit is connected to the first communication unit; an in-vivo module, including a second communication unit, a signal demodulation unit, and a signal processing unit, wherein the second communication unit is communicatively connected to the first communication unit, the second communication unit is also connected to the input end of the signal demodulation unit, the output end of the signal demodulation unit is connected to the signal processing unit, and the signal processing unit is used to extract the original biological signals from the signals output by the signal demodulation unit and determine biological body information based on the original biological signals. The in-vivo module in the present application only retains a signal acquisition unit for collecting original biological signals, an amplitude modulation unit for modulating the original biological signals to a carrier frequency band, and a first communication unit for communicating with the in-vivo module, while the signal processing unit, which is larger in size, high in power consumption, and prone to heat, is placed outside the in-vivo module. After receiving the modulated original biological signal, the in-vivo module first demodulates the signal, and then inputs the demodulated original biological signal into the signal processing unit for processing to obtain corresponding biological information. Thus, under the premise of ensuring the fidelity of the original biological signal, the signal processing unit and other large, high-power, and heat-prone devices are placed outside the body, which effectively reduces the size of the device implanted in the body, reduces the power consumption of the device implanted in the body, reduces the power burden, and improves the comfort of the user.

[0037] Other features and advantages of the present application will be described in the following description, and in part will become apparent from the description, or will be understood by practicing the present application. The purposes and other advantages of the present application can be achieved and obtained through the structures particularly pointed out in the description, claims and drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 Schematic diagram of the structure of a biological signal processing system proposed in an embodiment of the present application;

[0039] Figure 2 is a structural diagram of another biological signal processing system proposed in an embodiment of the present application;

[0040] Figure 3 is a structural diagram of another biological signal processing system proposed in an embodiment of the present application;

[0041] Figure 4 is a structural diagram of another biological signal processing system proposed in an embodiment of the present application;

[0042] Figure 5 This is a schematic diagram of the structure of another biological signal processing system proposed in the embodiment of the present application.

[0043] Figure 6 is a flow chart of a biological signal processing method proposed in an embodiment of the present application;

[0044] Figure 7 This is a flowchart of a biological signal processing method proposed in an embodiment of the present application;

[0045] Figure 8 yes Figure 6 Schematic diagram of the sub-process of step S605;

[0046] The accompanying drawings are used to provide a further understanding of the technical solution of the present application and constitute a part of the specification. Together with the embodiments of the present application, they are used to explain the technical solution of the present application and do not constitute a limitation on the technical solution of the present application. DETAILED DESCRIPTION

[0047] In order to make the purpose, technical solutions and advantages of this application more clearly understood, the following further describes this application in detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain this application and are not intended to limit this application.

[0048] It should be noted that although the device schematics illustrate functional module divisions and the flowcharts illustrate logical sequences, in certain circumstances, the steps shown or described may be executed in a sequence that differs from the module divisions in the device or the sequence in the flowcharts. The terms "first," "second," and so on, in the specification, claims, and drawings, are used to distinguish similar items and are not necessarily used to describe a specific sequence or precedence.

[0049] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which this application pertains. The terms used herein are for the purpose of describing the embodiments of this application only and are not intended to limit this application.

[0050] In addition, the described features, structures or characteristics may be combined in any suitable manner in one or more embodiments. In the following description, many specific details are provided to provide a full understanding of the embodiments of the present disclosure. However, those skilled in the art will appreciate that the technical solutions of the present disclosure can be practiced without one or more of the specific details, or other methods, components, devices, steps, etc. can be adopted. In other cases, well-known methods, devices, implementations or operations are not shown or described in detail to avoid blurring various aspects of the present disclosure.

[0051] In the description of the embodiments of the present application, unless otherwise clearly defined, terms such as setting, installing, and connecting should be understood in a broad sense. Technical personnel in the relevant technical field can reasonably determine the specific meanings of the above terms in the embodiments of the present application based on the specific content of the technical solution.

[0052] Reference Figure 1 , the embodiment of the present application proposes a biological signal processing system, comprising:

[0053] The in-vivo module includes a signal acquisition unit 101, an amplitude modulation unit 102, and a first communication unit 103. The signal acquisition unit 101 is used to acquire original biological signals. The amplitude modulation unit 102 includes a local oscillator signal generation unit 104 and a modulation unit 105. The local oscillator signal generation unit 104 is used to generate a local oscillator signal, which is used to modulate the original biological signal. The input end of the modulation unit 105 is respectively connected to the signal acquisition unit and the local oscillator signal generation unit 104, and the output end of the modulation unit 105 is connected to the first communication unit 103.

[0054] The in vitro module includes a second communication unit 201, a signal demodulation unit 202 and a signal processing unit 203, wherein the second communication unit 201 is communicatively connected to the first communication unit 103, the second communication unit 201 is also connected to the input end of the signal demodulation unit 202, the output end of the signal demodulation unit 202 is connected to the signal processing unit 203, and the signal processing unit 203 is used to determine the biological information based on the signal output by the signal demodulation unit 202.

[0055] The signal acquisition unit 101 can collect the original biological signals emitted by the organism in an active or passive manner. For example, the signal acquisition unit 101 can read biochemical electrical signals such as neural electrical signals and myoelectric signals through electrodes, or refer to Figure 3 The signal acquisition unit 101 may also be provided with an excitation circuit 204, which may generate a stimulation signal to stimulate the organism, so that the organism generates an original biological signal in response to the stimulation signal, and then collects the original biological signal at this time through electrodes or sensors. It is understood that the signal acquisition unit 101 may also collect the original biological signal through ultrasound, electrothermal, laser radar, etc. It is understandable that since the bioelectric signal is very weak, its amplitude is between microvolts and millivolts, referring to Figure 3 The signal acquisition unit 101 may further include at least one amplifier 109 . After acquiring the original biological signal, the original biological signal needs to be amplified before being injected into the modulation unit 105 .

[0056] The amplitude modulation unit 102 includes a local oscillator signal generation unit 104 and a modulation unit 105. The local oscillator signal generation unit 104 is used to generate a local oscillator signal, which is used to amplitude modulate the original biosignal. The signal is modulated into the radio frequency band of the first communication unit 103, and then transmitted to the external module through the first communication unit 103. The modulation unit 105 can be a mixer or a multiplier, and the local oscillator signal generation unit 104 can be a crystal oscillator, an oscillator, or a phase-locked loop circuit.

[0057] The first communication unit 103 is used to transmit the modulated signal to the extracorporeal module. Specifically, the extracorporeal module includes a second communication unit 201, a signal demodulation unit 202 and a signal processing unit 203, wherein the second communication unit 201 and the first communication unit 103 are communicatively connected, thereby transmitting the biological signal to the outside of the body for processing. In this way, the signal processing unit 203, which is large in size, high in power consumption and prone to heat, can be placed outside the body, thereby reducing the size of the device implanted in the body, reducing the power consumption of the device implanted in the body, improving the user's comfort and reducing the power burden.

[0058] After the external module receives the biological signal transmitted by the internal module, it first demodulates the biological signal through the signal demodulation module. The demodulation method can be mixing or envelope detection, which is not limited in this embodiment.

[0059] In this embodiment, the in-vivo module only retains the signal acquisition unit 101 for collecting the original biosignal, the amplitude modulation unit 102 for modulating the original biosignal to the carrier frequency band, and the first communication unit 103 for communicating with the in-vivo module. The signal processing unit 203, which is large in size, high in power consumption, and prone to heat generation, is placed externally as an in-vivo module. After receiving the biosignal, the in-vivo module first demodulates the signal to obtain a second biosignal, and then analyzes the second biosignal through the signal processing unit to determine the biological information. Based on this, by placing the large, high-power, and heat-prone components such as the signal processing unit 203 externally, the size of the implanted device is effectively reduced, the power consumption of the implanted device is reduced, the power burden is reduced, and the user's comfort is improved.

[0060] It is understandable that during the movement of an organism, a certain degree of relative displacement will occur between tissues such as muscles and skin, and the transmission distance between the internal module and the external module will change with the movement state of the organism. Since the movement state of the organism is irregular, the change in the transmission distance is also irregular. With the irregular change in the transmission distance, the transmission loss of the signal when it is transmitted from the internal module to the external module will also change irregularly. Due to the Doppler effect, this irregular change in the transmission distance will cause the biological signal to be distorted during the transmission process, resulting in distortion of the frequency and amplitude of the signal. Based on this, refer to Figure 2In some embodiments, a verification signal unit 106 is further connected between the signal acquisition unit 101 and the modulation unit 105, and includes a verification signal generation unit 107 and an adder 108. The verification signal generation unit 107 is used to generate a first verification signal. It is understood that the frequency and amplitude of the first verification signal generated by the verification signal generation unit are known, that is, the first verification signal is a single-tone signal or a multi-tone signal with a preset frequency and preset amplitude. Preferably, the first verification signal can be a single-tone signal generated according to the preset frequency and preset amplitude, such as a sine wave, cosine wave, or square wave signal with a fixed signal frequency. The input ends of the adder 108 are respectively connected to the signal acquisition unit 101 and the verification signal generation unit 107. The first verification signal is superimposed on the original biosignal through the adder 108, and the original biosignal after superimposing the first verification signal is then injected into the modulation unit for modulation. In this embodiment, the first verification signal can be set to a higher frequency so that after the first verification signal and the original biosignal are superimposed, the frequency of the first verification signal can be higher than the frequencies of all frequency components of the original biosignal, thereby distinguishing the first verification signal from the original biosignal. For example, the frequency of the human electromyographic signal is generally between 0 and 500 Hz, and the frequency of the first verification signal can be set to 600 Hz. In this way, the highest frequency component in the distorted first biosignal can be used as the frequency component corresponding to the first verification signal, thereby separating the distorted first biosignal to obtain the distorted first verification signal and the distorted original biosignal. The verification signal generation unit 107 can be a crystal oscillator, an oscillator, or a phase-locked loop circuit. The signal processing unit 203 can separate the distorted first verification signal and the distorted original biosignal from the second biosignal. Specifically, in this embodiment, the first verification signal can be set to a signal with a higher frequency than the original biosignal. The signal processing unit 203 can separate the distorted first verification signal and the distorted original biosignal from the distorted first biosignal by performing high-pass filtering and low-pass filtering on the first biosignal, respectively. Based on this, the frequency and amplitude of the distorted first verification signal are compared with the original frequency and amplitude used to generate the first verification signal, and the frequency distortion coefficient and amplitude distortion coefficient during the signal transmission process can be calculated. The distorted original biological signal is then compensated according to the frequency distortion coefficient and amplitude distortion coefficient. In this way, the distorted original biological signal can be restored, and the biological information of the organism can be analyzed based on the restored original biological signal.

[0061] In this embodiment, a verification signal unit is connected between the signal acquisition unit and the modulation unit, a first verification signal with known frequency and amplitude is generated by the verification signal generation unit, the first verification signal is superimposed on the original biological signal by an adder, and then the original biological signal after superimposing the first verification signal is injected into the modulation unit for modulation. Therefore, after the extracorporeal module receives the first biological signal transmitted from the intracorporeal module, the frequency component corresponding to the first verification signal can be separated therefrom, and the frequency component can be compared with the first verification signal to determine the frequency offset coefficient and amplitude offset coefficient of the signal during the process of transmission from the intracorporeal module to the extracorporeal module, thereby compensating for the original biological signal received by the extracorporeal module and ensuring the fidelity of the original biological signal.

[0062] In some embodiments, the first communication unit 103 and the second communication unit 201 are both coils or antennas, and the first communication unit and the second communication unit can communicate using a customized wireless communication standard. In this way, the communication standard can be adjusted for different application scenarios, thereby optimizing the modulation method, frequency and power of the device and reducing the size and power consumption of the device.

[0063] Reference Figure 4 In some embodiments, the signal acquisition unit 101 includes multiple signal acquisition subunits 301, each of which is connected to the input of the modulation unit. Each signal acquisition subunit 301 can be an electrode or a sensor. It is understood that when multiple signal acquisition subunits are provided, a multiplexer can be connected between each signal acquisition subunit and the modulation unit to select the channel output to the modulation unit. In this embodiment, at least one signal acquisition subunit 301 acquires bioelectrical signals from at least one biological tissue, which are then injected into the multiplexer 302. The multiplexer 302 selects the channel and outputs the raw bioelectrical signal collected by the corresponding signal acquisition subunit 301. For example, the multiplexer 302 can be driven by a built-in clock signal to rotate each channel to output the raw bioelectrical signal for a specific duration. In this case, the raw bioelectrical signal can be amplified before being injected into the multiplexer 302, or amplified after being injected into the multiplexer 302 to enhance the signal strength.

[0064] Reference Figure 5In some embodiments, an analog-to-digital conversion module 401 is connected between the signal demodulation unit 202 and the signal processing unit 203, and a filtering circuit 402 and / or an amplification circuit 403 are connected between the modulation unit 105 and the first communication module. It is understood that the original biosignal collected by the signal acquisition unit 101 is an analog signal, while the signal processing unit 203 is often a digital signal processor. Therefore, analog-to-digital conversion is required to convert the collected biosignal from analog to digital before it is input into the signal processing unit 203. Before transmitting the biosignal to the external module, the biosignal can also be filtered to remove some high-frequency noise. This ensures that the highest frequency component of the biosignal transmitted to the external module corresponds to the first verification signal. Furthermore, an amplification circuit can also be provided between the modulation unit 105 and the first communication unit 103 to amplify the biosignal before transmission, reducing interference caused by noise during signal transmission.

[0065] Reference Figure 6 The embodiment of the present application also discloses a biological signal processing method, which is applied to the above-mentioned biological signal processing system. The method includes but is not limited to the following steps S601 to S605.

[0066] Step S601, collecting original biological signals;

[0067] Step S602: modulating the original biosignal to obtain a first biosignal;

[0068] Step S603, transmitting the first biological signal to the second communication unit through the first communication unit;

[0069] Step S604: demodulating the first biosignal by a signal demodulation unit to obtain a second biosignal;

[0070] Step S605, determining biological information according to the second biological signal;

[0071] In step S601 of some embodiments, the original biological signal can be collected actively or passively, for example, by reading biochemical electrical signals such as neural electrical signals and myoelectric signals emitted by the organism through electrodes, or the signal collection unit can also be provided with an excitation circuit, which can generate a stimulation signal to stimulate the organism, so that the organism generates the original biological signal in response to the stimulation signal, and then collect the original biological signal at this time through electrodes or sensors. In addition, the signal collection unit can also collect the original biological signal through ultrasound, electrothermal, laser radar, etc. It is understandable that because the bioelectric signal is very weak, its amplitude is between microvolts and millivolts. Before the original biological signal is superimposed with the first verification signal to obtain the first biological signal, the original biological signal must be amplified to enhance the signal strength of the original biological signal.

[0072] In some embodiments, in step S602, the original biosignal may be amplitude modulated using a local oscillator signal to modulate the original biosignal to a specific radio frequency band. Specifically, the local oscillator signal may be generated by a crystal oscillator, an oscillator, or a phase-locked loop circuit. The original biosignal and the local oscillator signal are mixed to amplitude modulate the first biosignal to obtain the first biosignal.

[0073] In step S603 of some embodiments, the first communication unit and the second communication unit are communicatively coupled, and the second biosignal modulated into the radio frequency band is transmitted from the in-vivo module to the out-vivo module via the first communication unit. Specifically, the first communication unit and the second communication unit are both antennas or coils, and the first communication unit and the second communication unit can communicate with each other via the antennas or coils using a custom wireless communication standard. This allows the wireless communication standard to be adjusted for different application scenarios, optimizing frequency, power, and modulation methods, and reducing circuit size and power consumption.

[0074] In step S604 of some embodiments, after the extracorporeal module receives the first biological signal through the second communication unit, it can demodulate the first biological signal through the signal demodulation unit. The demodulation method can be mixing or envelope detection. After demodulation, the second biological signal is obtained. The second biological signal obtained by demodulation can be regarded as the original biological signal.

[0075] In some embodiments, in step S605, after the second biosignal is demodulated and obtained in the in vitro module, the second biosignal can be analyzed by the signal processing unit to obtain corresponding biological information. Specifically, the method for obtaining biological information by analyzing the original biosignal can refer to existing biological information processing equipment and is not limited in this embodiment.

[0076] The embodiment of the present application collects original biological signals in the body, modulates the collected original biological signals to a specific radio frequency band to form a first biological signal, and then transmits the first biological signal from the internal module to the external module through the first communication unit and the second communication unit. After receiving the first biological signal in the body, it is demodulated to obtain a second biological signal, and the second biological signal is analyzed in the body by the signal processing unit to obtain corresponding biological information. Based on this, the embodiment places the signal processing unit and other large, high-power, and heat-prone components outside the external module, and only retains the components with low power consumption, low volume sensitivity, and low heat generation in the body, effectively reducing the volume of the device implanted in the body, reducing the power consumption of the device implanted in the body, reducing the power burden, and improving the comfort of the user.

[0077] Reference Figure 7It is understandable that during the movement of an organism, a certain degree of relative displacement will occur between tissues such as muscles and skin. The transmission distance d between the first communication unit and the second communication unit will change as the movement state of the organism changes. The transmission distance can be recorded as d±Δd(t). Since the movement state of the organism is irregular, that is, Δd(t) is uncertain, which makes the change in the transmission distance irregular. With the irregular change in the transmission distance, the transmission loss of the signal when it is transmitted from the internal module to the external module will also change irregularly. Due to the Doppler effect, this irregular change in the transmission distance will cause the biological signal to be distorted during the transmission process, resulting in frequency offset and amplitude offset of the signal, causing signal distortion. Based on this, in this embodiment, before step S602, it can also include: generating a first verification signal; superimposing the first verification signal with the original biological signal to update the original biological signal. It can be understood that the frequency and amplitude of the first verification signal generated by the verification signal generating unit are known. Therefore, a first verification signal with known frequency and amplitude is superimposed on the original biological signal, so as to subsequently determine the coefficients of frequency offset and amplitude offset caused by distortion during signal transmission based on the first verification signal and the second verification signal formed by the distortion of the first verification signal.

[0078] In some preferred embodiments, the first verification signal can be a single-tone signal generated according to a preset frequency and amplitude. For example, the first verification signal can be a sine wave, cosine wave, or square wave with a fixed frequency and amplitude. This allows for easier calculation of the frequency offset and amplitude during signal transmission based on the first verification signal and a second verification signal formed by distorting the first verification signal. It is understood that the first verification signal can also be a multi-tone signal having a preset frequency and amplitude.

[0079] Reference Figure 8 In some embodiments, step S605 further includes but is not limited to the following steps S801 to S804:

[0080] Step S801, separating a second verification signal and a third biosignal from the second biosignal;

[0081] Step S802, determining a distortion coefficient according to the first calibration signal and the second calibration signal;

[0082] Step S803, restoring the third biosignal to the original biosignal according to the distortion coefficient;

[0083] Step S804: Determine biological information based on the original biological signal.

[0084] In step S801 of some embodiments, the second biosignal is composed of a distorted original biosignal and a distorted first verification signal. A corresponding second verification signal and third biosignal can be separated from the second biosignal, wherein the second verification signal is the distorted first verification signal, and the third biosignal is the distorted original biosignal. It will be appreciated that in this embodiment, the set frequency of the first verification signal is higher than the frequencies of all frequency components of the original biosignal. Therefore, by setting an appropriate critical value based on the set frequency of the first verification signal and then performing high-pass and low-pass filtering on the second biosignal based on the critical value, the second verification signal and the third biosignal can be separated from the second biosignal.

[0085] In step S802 of some embodiments, since the first verification signal is generated based on a preset frequency and preset amplitude, that is, the frequency and amplitude of the first verification signal are known, the preset frequency and preset amplitude are compared with the frequency and amplitude of the second verification signal to determine the distortion coefficient of the frequency and amplitude when the signal is transmitted from the in vivo module to the extracorporeal module. The frequency and amplitude of the second verification signal are obtained by performing a Fourier transform on the second verification signal. Specifically, the frequency domain expression of the second verification signal can be organized as follows:

[0086]

[0087] Among them, A rc (t) is the second verification signal, A′ c is the amplitude of the first calibration signal, ω c is the frequency of the first calibration signal, A′ c -ΔA′ c (t) is the amplitude of the second calibration signal, j[ω c -Δω c (t)]t is the phase of the second verification signal at time t, ω c -Δω c (t) is the frequency of the second calibration signal, ΔA′ c (t) is the amplitude distortion coefficient of the signal when it is transmitted between the first communication unit and the second communication unit, Δω c (t) is the frequency distortion coefficient of the signal when it is transmitted between the first communication unit and the second communication unit, e is a natural constant, and j is an imaginary unit. Since the preset frequency and preset amplitude of the first verification signal are both known, that is, A′ c and ω c It is known that the amplitude and frequency of the second verification signal can be determined by performing a fast Fourier transform on the second verification signal, that is, A′ c -ΔA′ c The value of (t) and ω c -Δω cThe value of (t) is also known. Based on this, the frequency distortion coefficient ΔA′ can be determined according to the frequency of the first calibration signal and the frequency of the second calibration signal. c (t), determine the amplitude distortion coefficient Δω according to the amplitude of the second verification signal and the amplitude of the second verification signal x (t). .

[0088] In step S803 of some embodiments, after determining the distortion coefficient during signal transmission by using the first verification signal and the second verification signal, the third biosignal can be restored to the original biosignal based on the distortion coefficient. It can be understood that the first verification signal is superimposed on the original biosignal and then modulated and transmitted, and the distortion of the signal during transmission is mainly due to the frequency offset and amplitude offset caused by the Doppler effect. The frequency offset and amplitude offset of the first verification signal are synchronized with the frequency offset and amplitude offset of the original biosignal. The third biosignal can be restored to the original biosignal by compensating for the distortion coefficient during transmission of the first verification signal. Specifically, the third biosignal is subjected to a fast Fourier transform to obtain the frequency and amplitude of the third biosignal. Specifically, the third biosignal after the Fourier transform can be expressed by the following formula:

[0089]

[0090] Among them, A rs (t) is the third biosignal, [A′ m -ΔA′ c (t)] is the amplitude of the mth frequency component of the third biosignal, A′ m is the amplitude of the mth frequency component of the original biological signal, ΔA′ c (t) is the amplitude distortion coefficient, j[ω m -Δω c (t)]t is the phase of the mth frequency component of the third biological signal at time t, where ω m -Δω c (t) is the frequency of the mth frequency component of the third biosignal, ω m is the frequency of the mth frequency component of the original biological signal, Δω c (t) is the frequency distortion coefficient, n represents the number of frequency components of the third biological signal, m is a positive integer ranging from 1 to n, e is a natural constant, and j is an imaginary unit. c (t) and frequency distortion coefficient Δω c (t) Based on the first verification signal and the second verification signal, the amplitudes of the frequency components of the third biological signal [A′] can also be determined after Fourier transforming the third biological signal. m -ΔA′ c(t)] and frequency [ω m -Δω c (t)], and the frequency distortion coefficient ΔA′ c (t) and Δω c (t) The frequency A′ of the original biosignal is determined based on the frequency and frequency distortion coefficient of the third biosignal, having been determined by the first verification signal and the second verification signal. m ; Determine the amplitude ω of the original biosignal according to the amplitude and amplitude distortion coefficient of the third biosignal m Based on this, the third biological signal can be restored to the original biological signal. The frequency domain expression of the original biological signal is as follows:

[0091]

[0092] Among them, A s (t) is the original biological signal, A′ m is the amplitude of the mth frequency component of the original biological signal, jω m t is the phase of the mth frequency component of the original biological signal at time t, ω m is the frequency of the mth frequency component of the original biological signal, n represents the number of frequency components of the original biological signal, and the value range of m is a positive integer from 1 to n.

[0093] An embodiment of the present application further provides an electronic device comprising the biosignal processing system as described above.

[0094] The flowcharts shown in the accompanying drawings are for illustrative purposes only and do not necessarily include all contents and operations / steps, nor do they necessarily need to be executed in the order described. For example, some operations / steps may be decomposed, while others may be combined or partially combined. Therefore, the actual execution order may vary depending on the actual situation.

[0095] Those skilled in the art will appreciate that all or some of the steps in the methods, systems, and functional modules / units in the devices disclosed above may be implemented as software, firmware, hardware, or appropriate combinations thereof.

[0096] The terms "including" and "having" and any variations thereof in the specification of this application and the above-mentioned drawings are intended to cover non-exclusive inclusions. For example, a process, method, system, product or apparatus that includes a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units that are not explicitly listed or are inherent to these processes, methods, products or apparatuses.

[0097] It should be understood that in this application, "at least one (item)" means one or more, and "plurality" means two or more. "And / or" is used to describe the association relationship of associated objects, indicating that three relationships may exist. For example, "A and / or B" can mean: only A exists, only B exists, and A and B exist at the same time, where A and B can be singular or plural. The character " / " generally indicates that the previous and next associated objects are in an "or" relationship. "At least one of the following items" or similar expressions refers to any combination of these items, including any combination of single items or plural items. For example, at least one of a, b or c can mean: a, b, c, "a and b", "a and c", "b and c", or "a and b and c", where a, b, c can be single or multiple.

[0098] The units described as separate components may or may not be physically separate, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed across multiple network units. Some or all of these units may be selected to achieve the purpose of this embodiment according to actual needs.

[0099] The preferred embodiments of the present invention are described above with reference to the accompanying drawings, but are not intended to limit the scope of the present invention. Any modifications, equivalent substitutions, and improvements made by those skilled in the art without departing from the scope and essence of the present invention should be within the scope of the present invention.

Claims

1. A biological signal processing system, characterized in that: include: An in-vivo module, comprising a signal acquisition unit, an amplitude modulation unit, and a first communication unit, wherein the signal acquisition unit is used to acquire original biological signals, the amplitude modulation unit comprises a local oscillator signal generating unit and a modulation unit, the local oscillator signal generating unit is used to generate a local oscillator signal, the local oscillator signal is used to modulate the original biological signals, the input end of the modulation unit is respectively connected to the signal acquisition unit and the local oscillator signal generating unit, the output end of the modulation unit is connected to the first communication unit, a verification signal unit is further connected between the signal acquisition unit and the modulation unit, the verification signal unit comprises a verification signal generating unit and an adder, the verification signal generating unit is used to generate a first verification signal, the input end of the adder is respectively connected to the signal acquisition unit and the verification signal generating unit, and the output end of the adder is connected to the input end of the modulation unit; An in vitro module, comprising a second communication unit, a signal demodulation unit and a signal processing unit, wherein the second communication unit is communicatively connected to the first communication unit, the second communication unit is also connected to the input end of the signal demodulation unit, the output end of the signal demodulation unit is connected to the signal processing unit, and the signal processing unit is used to extract the original biological signal from the signal output by the signal demodulation unit and determine the biological body information according to the original biological signal; The extracting the original biological signal from the signal output by the signal demodulation unit and determining the biological body information according to the original biological signal comprises: A second verification signal and a third biological signal are separated from the signal output from the signal demodulation unit, a distortion coefficient is determined based on the first verification signal and the second verification signal, and the third biological signal is restored to the original biological signal based on the distortion coefficient.

2. The biological signal processing system according to claim 1, characterized in that: The first verification signal is a single-tone signal or a multi-tone signal with a preset amplitude and a preset frequency.

3. The biological signal processing system according to claim 1, characterized in that: The signal acquisition unit includes at least one signal acquisition subunit, each of which is connected to the input end of the modulation unit, and the signal acquisition subunit is an electrode or a sensor.

4. The biological signal processing system according to claim 3, characterized in that: A multiplexer is arranged between the signal acquisition subunit and the input end of the modulation unit.

5. A biological signal processing method, applied to the biological signal processing system according to any one of claims 1 to 4, characterized in that: The method comprises: Collecting original biological signals; superimposing the first verification signal with the original biological signal to update the original biological signal; Modulating the original biological signal to obtain a first biological signal; transmitting the first biological signal to the second communication unit through the first communication unit; Demodulating the first biological signal by the signal demodulation unit to obtain a second biological signal; separating a second verification signal and a third biological signal from the second biological signal; determining a distortion coefficient according to the first verification signal and the second verification signal; Restoring the third biological signal to the original biological signal according to the distortion coefficient; The biological body information is determined according to the original biological signal.

6. The biological signal processing method according to claim 5, characterized in that: Before modulating the original biological signal to obtain the first biological signal, the method further includes: A first verification signal is generated according to a preset frequency and a preset amplitude, wherein the first verification signal is a single-tone signal or a multi-tone signal.

7. The biological signal processing method according to claim 5, characterized in that: The determining the distortion coefficient according to the first verification signal and the second verification signal comprises: Performing Fourier transform on the second verification signal to obtain the frequency and amplitude of the second verification signal; Determining a frequency distortion coefficient according to a preset frequency and a frequency of the second verification signal; An amplitude distortion coefficient is determined according to a preset amplitude and the amplitude of the second verification signal.

8. The biological signal processing method according to claim 7, characterized in that: The restoring the third biological signal to the original biological signal according to the distortion coefficient includes: Performing Fourier transform on the third biological signal to obtain the frequency and amplitude of the third biological signal; determining the frequency of the original biosignal according to the frequency of the third biosignal and the frequency distortion coefficient; The amplitude of the original biosignal is determined according to the amplitude of the third biosignal and the amplitude distortion coefficient.

9. An electronic device, characterized in that: The biological signal processing system comprises the biological signal processing system as claimed in any one of claims 1 to 4.

Images