Electrophoresis device

Abstract

The present invention belongs to the technical field of electrophoresis tanks for biological protein gels, and provides an electrophoresis device, which includes an electrophoresis tank body, a first cavity, a detachable electrode holder, which is arranged in the first cavity of the electrophoresis tank body, and the electrode holder is provided with a positive electrode wire and a negative electrode wire for forming a uniform electric field; a prefabricated glue plate is provided, and the glue plate is detachably arranged on one side of the first experimental port of the electrode holder, and the glue plate can seal the first experimental port of the electrode holder; a connecting frame is arranged on one side of the electrophoresis tank body, and is used for connecting two adjacent electrophoresis tank bodies, and the electrode holder is provided with a plurality of first terminals, and the first terminals are respectively electrically connected to the positive electrode wire and the negative electrode wire, so as to realize the series connection and parallel connection of the circuits of the two adjacent electrophoresis tank bodies. The present application realizes the simultaneous gel running experiment of multiple glue plates by setting a connecting frame to splice multiple electrophoresis tank bodies, and sets the electrode holder into a detachable structure, which is convenient for the replacement of parts and reduces the experimental cost.

Description

Technical Field

[0001] The invention belongs to the technical field of electrophoresis tanks for biological protein gels, in particular to an electrophoresis device. Background Art

[0002] In molecular biology experiments, the use of gel electrophoresis to detect experimental results is an indispensable experimental method, and in the experiment, the electrophoresis device is an indispensable experimental tool.

[0003] In the prior art, gel separation experiments can usually only be performed in a single electrophoresis tank. When a multi-sheet prefabricated gel separation experiment is required, a single electrophoresis tank in the prior art cannot meet the experimental requirements. When the number of prefabricated films increases, the sealing requirements for the separation of the electrophoresis tanks are high, and there may be leakage, resulting in inaccurate experimental results. At the same time, if a simple single electrophoresis tank is superimposed, the electrophoresis tank is prone to distribution disorder. Based on the prior art, multiple power cords need to be connected, or multiple power supplies need to be provided, resulting in an increase in equipment or complex line connections, which is very inconvenient for experimenters to operate. In the prior art, the electrode bracket is all set as a whole, and a wiring groove is opened on the electrode bracket, and then the positive and negative electrode wires are wound. When the positive and negative electrode wires or the support frame are damaged, it is often necessary to replace the entire electrode bracket or rewind the positive and negative electrode wires. The positive and negative electrode wires are generally platinum wires that are easy to break and difficult to wind. If the entire bracket is replaced, the cost is relatively high. Summary of the invention

[0004] The present invention provides an electrophoresis device to solve the problems in the above-mentioned background technology that a single electrophoresis tank cannot meet the experimental requirements of multiple precast gels, multiple precast gels are set in a single electrophoresis tank and leakage may occur; when the electrode bracket is damaged, the positive and negative electrode wires are not easy to be entangled or the cost of replacing the entire electrode bracket is high.

[0005] In order to achieve the above object, the present invention adopts the following technical solution:

[0006] An electrophoresis device, comprising:

[0007] The electrophoresis tank body has a first cavity, and the electrophoresis tank body is provided with a first opening connecting the first cavity with the outside;

[0008] An electrode holder is disposed in the first cavity of the electrophoresis tank body, the electrode holder has a second cavity, a second opening communicating with the second cavity, and a first experimental port communicating with the second cavity, the electrode holder is provided with a positive electrode wire and a negative electrode wire, the positive electrode wire and the negative electrode wire can form a uniform electric field, the positive electrode wire portion is located outside the second cavity, and the negative electrode wire portion is located inside the second cavity;

[0009] A glue plate, on which prefabricated glue is provided, the glue plate is detachably arranged on the electrode bracket, and the glue plate can seal the first experimental port of the electrode bracket so that the first cavity and the second cavity are relatively independent;

[0010] A connecting frame is arranged on one side of the electrophoresis tank body, and is used to connect two adjacent electrophoresis tank bodies. The connecting frame is provided with a plurality of first terminals, and the first terminals are respectively electrically connected to the corresponding positive electrode wire and the negative electrode wire. The plurality of first terminals on two adjacent connecting frames are electrically connected correspondingly, so that the circuits between the two adjacent electrophoresis tank bodies are connected in series or in parallel.

[0011] In some embodiments, the electrode bracket includes a support frame body, a positive electrode assembly and a negative electrode assembly, wherein the support frame body is provided with a first mounting groove adapted to the positive electrode bracket and a second mounting groove adapted to the negative electrode bracket, the positive electrode assembly can be removably arranged on the first mounting groove of the support frame body, and the negative electrode assembly can be removably arranged on the second mounting groove of the support frame body.

[0012] In some embodiments, the positive electrode assembly includes a positive electrode support and a positive electrode terminal disposed on the positive electrode support, the negative electrode assembly includes a negative electrode support and a negative electrode terminal disposed on the negative electrode support, the positive electrode wire is disposed on the positive electrode support and is electrically connected to the positive electrode terminal, and the negative electrode wire is disposed on the negative electrode support and is electrically connected to the negative electrode terminal.

[0013] In some embodiments, the positive electrode support is provided with a first wiring groove, the positive electrode wire includes a first insulating section and a first exposed section, the first insulating section of the positive electrode wire is located in the first wiring groove, and the first exposed section of the positive electrode wire is fixed to the positive electrode support.

[0014] In some embodiments, the negative electrode support is provided with a second wiring groove, the negative electrode wire includes a second insulating section and a second exposed section, the second insulating section of the negative electrode wire is located in the second wiring groove, and the second exposed section of the negative electrode wire is fixed on the negative electrode support, wherein the second exposed section of the negative electrode wire corresponds to the first exposed section of the positive electrode wire and is relatively parallel.

[0015] In some embodiments, the positive electrode support is provided with a first fixing structure, and the first exposed section of the positive electrode wire is fixed to the positive electrode support through the first fixing structure; the negative electrode support is provided with a second fixing structure, and the second exposed section of the negative electrode wire is fixed to the negative electrode support through the second fixing structure.

[0016] In some embodiments, the distance between the second exposed section of the negative electrode wire and the bottom wall of the electrode support is half the depth of the second cavity of the electrode support.

[0017] In some embodiments, the positive electrode wire and the positive electrode support are integrally arranged, and the negative electrode wire and the negative electrode support are integrally arranged.

[0018] In some embodiments, the connecting frame is integrally provided with the electrophoresis tank body.

[0019] In some embodiments, the connecting frame is detachably connected to the electrophoresis tank body.

[0020] In some embodiments, the connecting frame includes a snap-in boss and a snap-in groove adapted thereto. When two adjacent electrophoresis tank bodies are connected, the snap-in boss of the connecting frame of the first electrophoresis tank body is snap-into the snap-in groove of the connecting frame of the second electrophoresis tank body, or the snap-in groove of the connecting frame of the first electrophoresis tank body is snap-into the snap-in boss of the connecting frame of the second electrophoresis tank body.

[0021] In some embodiments, the electrophoresis tank body is tilted so that there is a misalignment between two adjacent electrophoresis tank bodies.

[0022] In some embodiments, a connecting plate is provided between the connecting frame and the electrophoresis tank body, and a preset angle is provided between the connecting plate and the electrophoresis tank body so that the electrophoresis tank body is tilted relative to the connecting frame.

[0023] In some embodiments, the snap-in groove is provided with a first boss, and the snap-in boss is provided with a matching first notch. When two adjacent electrophoresis tank bodies are connected, the first boss of the first electrophoresis tank body is snap-fitted to the first notch of the second electrophoresis tank body.

[0024] In some embodiments, the first notch is arranged along the side of the connecting frame, and when the first boss of the connecting frame of the first electrophoresis tank body is snapped onto the first notch of the connecting frame of the second electrophoresis tank body, the snap-on boss of the connecting frame of the second electrophoresis tank body abuts against the side wall of the connecting frame of the first electrophoresis tank body.

[0025] In some embodiments, the connecting frame is provided with a first mounting plate on one side of the snap-in boss, and the first mounting plate is provided with a plurality of second terminals electrically connected to the plurality of first terminals and a first clearance groove corresponding to the position of the first notch. When two adjacent electrophoresis tank bodies are connected, the first mounting plate on the connecting frame of the second electrophoresis tank body abuts against the connecting frame of the first electrophoresis tank body.

[0026] In some embodiments, the connecting frame is provided with a first support plate located on one side of the snap-in groove, and the first support plate is provided with a plurality of first through holes adapted to the plurality of second terminal posts. When two adjacent electrophoresis tank bodies are connected, one end of the plurality of second terminal posts located on the first mounting plate of the second electrophoresis tank body passes through the plurality of first through holes located on the first support plate of the first electrophoresis tank body, and the first support plate abuts against the adjacent side wall of the connecting frame.

[0027] In some embodiments, a first slot cover is further included, which can be removably arranged at the first opening of the electrophoresis tank body, and a plurality of wiring caps are arranged on the first slot cover, and a pre-connection circuit is arranged between the plurality of wiring caps. The plurality of wiring caps are respectively plugged into the first terminal, the positive terminal and the negative terminal in a one-to-one correspondence to realize the series or parallel connection of the circuit between two adjacent electrophoresis tank bodies.

[0028] In some embodiments, the first slot cover is provided in two different colors, and the first slot covers of the two different colors are respectively provided with different pre-connection circuits.

[0029] In some embodiments, the electrophoresis tank body is a single gel tank structure, the first experimental port of the electrode bracket is set on one side, a preset distance is set between the electrode bracket and the electrophoresis tank body, and the gel plate can be removably set within the preset distance.

[0030] In some embodiments, a first sealing groove is provided on one side of the first experimental port of the electrode bracket, a first sealing strip is provided in the first sealing groove, and the first sealing strip partially protrudes out of the first sealing groove. When the rubber plate is set within the preset spacing, the first sealing strip is in an extruded state.

[0031] In some embodiments, the first sealing strip is detachably disposed on the first sealing groove, and a clamping step is disposed on a side of the first sealing strip away from the bottom wall of the electrophoresis tank body.

[0032] In some embodiments, a first snap-in groove is provided on the electrophoresis tank body, and a first snap-in boss is provided on the electrode bracket. When the first snap-in boss of the electrode bracket is snapped onto the first snap-in groove of the electrophoresis tank body, the side wall of the electrode bracket abuts against the side wall of the electrophoresis tank body.

[0033] In some embodiments, a pressing plate is provided between the gel plate and the inner wall of the electrophoresis tank, one side of the pressing plate abuts against the gel plate, and the other side of the pressing plate abuts against the inner wall of the electrophoresis tank.

[0034] In some embodiments, the outer shape structure of the pressing plate is the same as the structure of the first sealing groove, and the pressing plate can cover the first sealing groove.

[0035] In some embodiments, the pressing plate is provided with a guide column, and the electrode bracket is provided with a matching guide hole, or the pressing plate is provided with a guide hole, and the electrode bracket is provided with a guide column, and the guide column is inserted into the guide hole.

[0036] Compared with the prior art, the present invention has the following beneficial effects:

[0037] By setting up a connecting frame, two adjacent electrophoresis tank bodies are connected, and at the same time, the first terminal and the second terminal, the positive terminal and the negative terminal set on the connecting frame are combined, and the first slot cover with the circuit pre-set is snapped together to realize the series or parallel connection of the circuit between the two adjacent electrophoresis tank bodies, provide a constant voltage or constant current mode, and realize the running experiment of multiple gel plates to meet the experimental needs. At the same time, by splitting the electrode bracket into a support frame, a positive electrode assembly, and a negative electrode assembly, when a component of the electrode bracket is damaged, a single component can be replaced without the need for overall replacement, and the replacement method is simple, saving costs.

[0038] Additional aspects and advantages of the present application will be partially given in the following description, which will become apparent from the following description, or will be understood through the practice of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 is a first stereoscopic view of a single structure of the electrophoresis device of the present invention;

[0040] Figure 2 is a second stereoscopic view of a single structure of the electrophoresis device of the present invention;

[0041] Figure 3 is a three-dimensional diagram of a connecting frame of an electrophoresis device of the present invention;

[0042] Figure 4 It is a schematic diagram of a first three-dimensional structure of an electrode support of an electrophoresis device of the present invention;

[0043] Figure 5 A first stereoscopic view of the support frame body of the electrode support of the present invention;

[0044] Figure 6 A second stereoscopic view of the support frame body of the electrode support of the present invention;

[0045] Figure 7 It is a schematic diagram of the three-dimensional structure of the positive electrode support of the electrode support of the present invention;

[0046] Figure 8A top view of a positive electrode support of an electrode support of the present invention;

[0047] Fig. 9 It is a schematic diagram of the three-dimensional structure of the negative electrode support of the electrode support of the present invention;

[0048] Fig.10 A top view of a negative electrode support of an electrode support of the present invention;

[0049] Fig.11 It is a schematic diagram of the three-dimensional structure of the electrophoresis tank body of the present invention;

[0050] Fig.12 It is a schematic diagram of the assembly of the rubber plate and the electrode support of the present invention;

[0051] Fig.13 An exploded view of the rubber plate and the electrode support of the present invention;

[0052] Fig.14 is a top view of the electrophoresis device of the present invention;

[0053] Fig.15 A top view of another variant embodiment of the electrophoresis device of the present invention;

[0054] Fig.16 It is a schematic diagram of the three-dimensional structure of the first sealing strip of the electrode support of the present invention;

[0055] Fig.17 A schematic diagram of a three-dimensional structure of a plurality of electrophoresis devices of the present invention being assembled and spliced;

[0056] Fig.18 A top view of a plurality of electrophoresis devices of the present invention being assembled and spliced;

[0057] Fig.19 It is a schematic diagram of the series and parallel connection of the circuits of multiple electrophoresis devices of the present invention. DETAILED DESCRIPTION

[0058] The present application is further described in detail below in conjunction with specific drawings. In the description of this embodiment, unless otherwise specified, the terms "left", "right", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, which are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the present application must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as limiting the present application.

[0059] like Figure 1 and Figure 2 As shown, an electrophoresis device provided by the present invention mainly includes an electrophoresis tank body 100, an electrode bracket 300, a gel plate 500 and a connecting frame 200.

[0060] The electrophoresis tank body 100 has a first cavity 102 and a first opening connecting the first cavity 102 with the outside. Figure 2 The electrode holder 300 is detachably disposed in the first cavity 102 of the electrophoresis tank body 100, and the electrode holder 300 has a second cavity 3016, a second opening connecting the second cavity 3016 with the outside, and a first experimental port connected to the second cavity, wherein the second opening is as shown in FIG. Figure 4 The direction shown is upward, and the first experimental port is as follows Figure 4 As shown, it is arranged on the side of the electrode holder 300;

[0061] The electrode holder 300 is a detachable structure, and a positive electrode wire and a negative electrode wire are provided on the electrode holder 300. The positive electrode wire and the negative electrode wire are respectively connected to the positive and negative electrodes of the power supply so that a uniform electric field can be formed between the positive electrode wire and the negative electrode wire. The positive electrode wire is located outside the second cavity 3016, and the negative electrode wire is partially located inside the second cavity 3016. In this embodiment, the positive electrode wire and the negative electrode wire are both platinum wires. Optionally, the positive electrode wire and the negative electrode wire can also be other conductive metals, such as silver or copper;

[0062] Prefabricated glue is arranged on the glue plate 500, and the glue plate 500 can be detachably arranged on the electrode holder 300, and the glue plate 500 can seal the first experimental port. When performing the gel running experiment, the first cavity 102 and the second cavity 3016 are filled with buffer solution, and the glue plate 500 seals the first experimental port, thereby insulating the positive electrode wire in the first cavity 102 and the negative electrode wire inside the second cavity 3016, so as to form the electric field required for the experiment;

[0063] The connecting frame 200 is arranged on one side of the electrophoresis tank body 100. The connecting frame 200 is mainly used for splicing two adjacent electrophoresis tank bodies 100, wherein a first terminal 201 is provided on the connecting frame 200. In this embodiment, the number of the first terminal 201 is 3, and the first terminal 201 is electrically connected to the corresponding positive electrode wire and the negative electrode wire respectively, so as to realize the series or parallel connection of the circuit between the two adjacent spliced ​​electrophoresis tank bodies 100, and provide the constant current or constant voltage experimental mode required for the experiment.

[0064] The present application sets the electrode holder 300 to a detachable structure. When a part of the electrode holder 300 is damaged, compared with the traditional electrode holder 300 with an integrated structure, the electrode holder 300 of the present application can partially replace the damaged parts without replacing the entire part, saving costs. At the same time, the operation is simple and does not require a complicated operation process. On the other hand, by setting a connecting frame 200, it is possible to splice multiple electrophoresis tank bodies 100. At the same time, a first terminal 201 is set on the connecting frame 200 to respectively make corresponding electrical connections with the positive wire and the negative wire, and select a constant current series circuit or a constant voltage parallel circuit according to experimental requirements, such as Fig.19 As shown, the experimental requirements are met and the running experiments of multiple rubber plates 500 can be satisfied, thus saving experimental time and improving experimental efficiency.

[0065] In one embodiment, Figure 4-10 As shown, the electrode support 300 can be disassembled into a support frame body 301, a positive electrode assembly 302 and a negative electrode assembly 303, wherein the positive electrode assembly 302 and the negative electrode assembly 303 are both detachably arranged on the support frame body 301. Specifically, as Figure 5 As shown, a first mounting groove 3011 and a second mounting groove 3012 are provided on the support frame body 301, the first mounting groove 3011 is adapted to the positive electrode bracket 3022, and the second mounting groove 3012 is adapted to the negative electrode bracket 3032, the positive electrode bracket 3022 is detachably mounted on the first mounting groove 3011, and the negative electrode bracket 3032 is detachably mounted on the second mounting groove 3012. It should be particularly noted that when the positive electrode bracket 3022 and the negative electrode bracket 3032 are correspondingly mounted on the first mounting groove 3011 and the second mounting groove 3012, the positive electrode bracket 3022 will not protrude from the side of the support frame body 301, and the negative electrode bracket 3032 will not protrude from the side of the support frame body 301, that is, Figure 8 and Fig.10As shown, the thickness A of the positive electrode support 3022 is less than or equal to the groove depth of the first installation groove 3011, and the thickness B of the negative electrode support 3032 is less than or equal to the groove depth of the second installation groove 3012. Further, the positive electrode assembly 302 includes a positive electrode support 3022 and a positive electrode terminal 3021, and the positive electrode terminal 3021 is arranged on the positive electrode support 3022, and the negative electrode assembly 303 includes a negative electrode support 3032 and a negative electrode terminal 3031, and the negative electrode terminal 3031 is arranged on the negative electrode support 3032, wherein the positive electrode wire is arranged on the positive electrode support 3022, and one end of the positive electrode wire is electrically connected to the positive electrode terminal 3021, and the negative electrode wire is arranged on the negative electrode support 3032, and one end of the negative electrode wire is electrically connected to the negative electrode terminal 3031. Specifically, a first threaded hole 3013 is set on the support frame body 100, and a second through hole 30222 is set on the positive electrode bracket 3022. The positive electrode bracket 3022 is fixed by a first screw passing through the second through hole 30222 and inserted into the first threaded hole 3013. Similarly, a second threaded hole 3014 is set on the support frame body 301, and a third through hole 30322 is set on the negative electrode bracket 3032. The negative electrode bracket 3032 is fixed by a second screw passing through the third through hole 30322 and inserted into the second threaded hole 3014.

[0066] In one embodiment, a first wiring groove 30221 is provided on the positive electrode support 3022, and the positive electrode wire includes a first insulating section and a first exposed section, the first insulating section of the positive electrode wire is provided in the first wiring groove 30221, and the first exposed section of the positive electrode wire is exposed outside the positive electrode support 3022 and located outside the second cavity 3016. Further, similarly, a second wiring groove 30321 is provided on the negative electrode support 3032, and the negative electrode wire includes a second insulating section and a second exposed section, wherein the second insulating section of the negative electrode wire is located in the second wiring groove 30321, and the second exposed section of the negative electrode wire is exposed outside the negative electrode support 3032 and located inside the second cavity 3016. It should be pointed out that in order to facilitate the formation of a uniform electric field, the second exposed section of the negative electrode wire and the first exposed section of the positive electrode wire are arranged in corresponding positions and are arranged relatively parallel. Furthermore, the positive electrode wire and the positive electrode bracket 3022 can also be set as an integrated structure, that is, the first insulating section of the positive electrode wire is integrated with the positive electrode bracket 3022, and the first exposed section of the positive electrode wire is located outside the positive electrode bracket 3022; similarly, the negative electrode bracket 3032 and the negative electrode wire are integrated, that is, the second insulating section of the negative electrode wire is integrated with the negative electrode bracket 3032, and the second exposed section of the negative electrode wire is located outside the negative electrode bracket 3032. Furthermore, since platinum wire is relatively expensive, the first insulating section of the positive electrode wire and the second insulating section of the negative electrode wire can also be set as copper or silver metal wires, and the first exposed section of the positive electrode wire and the second exposed section of the negative electrode wire can be set as platinum wire, and the same experimental effect can be achieved.

[0067] In one embodiment, in order to facilitate the fixing of the first exposed section of the positive wire and the second exposed section of the negative wire, a first fixing structure 30223 is provided on the positive bracket 3022 to fix the first exposed section of the positive wire, and a second fixing structure 30323 is provided on the negative bracket 3032 to fix the second exposed section of the negative wire. In this embodiment, the first fixing structure 30223 and the second fixing structure 30323 are both fixing holes. Optionally, the first fixing structure 30223 and the second fixing structure 30323 can also be fixed column structures.

[0068] In one embodiment, Figure 4 As shown, in order to achieve better experimental results, since heat is generated during the experiment, the heat is transferred upward from the bottom of the electrode holder 300. When the first exposed section of the negative electrode wire is located at the bottom of the electrode holder 300, during the experiment, the temperature is normal at the beginning, and the gel running experiment is normal. The longer the time, the greater the heat in the lower part. As the heat transfer increases, due to the temperature difference, the gel running effect will appear in a trapezoidal structure, resulting in poor gel running effect. When the second exposed section of the negative electrode wire is located at the lofting notch, due to the proximity to the lofting source, the buffer solution is less, resulting in poor gel running experiment results. After multiple experiments and comparisons, it is found that when the distance between the second exposed section of the negative electrode wire and the bottom wall of the electrode holder 300 is set to half the depth of the second cavity 3016 of the electrode holder 300, the best gel running experiment effect is achieved.

[0069] In one embodiment, the connection frame 200 is integrally provided with the electrophoresis tank body 100. Optionally, the connection frame 200 and the electrophoresis tank body 100 can also be a detachable connection structure.

[0070] Furthermore, if Figure 3 As shown, the connecting frame 200 includes a snap-in boss 202 and a snap-in groove 2032 adapted thereto. When two adjacent electrophoresis tank bodies 100 are connected, the snap-in boss 202 of the connecting frame 200 of the first electrophoresis tank body 100 is snap-into the snap-in groove 2032 of the connecting frame 200 of the second electrophoresis tank body 100, or the snap-in groove 2032 of the connecting frame 200 of the first electrophoresis tank body 100 is snap-into the snap-in boss 202 of the connecting frame 200 of the second electrophoresis tank body 100.

[0071] In one embodiment, Figure 17-18 As shown, in order to facilitate real-time observation of the experimental process, the electrophoresis tank body 100 is tilted so that two adjacent electrophoresis tank bodies 100 are offset, as shown in FIG. Fig.18As shown, a third visible distance 104 is formed between the first electrophoresis tank body 100 and the second electrophoresis tank body 100, so that the gel running experiment process of the gel plate 500 located on the electrode bracket 300 can be observed in real time. Furthermore, in order to reduce the volume of the electrophoresis tank body 100, since it is necessary to stagger the two adjacent electrophoresis tank bodies 100, a connecting plate 101 is set between the electrophoresis tank body 100 and the connecting frame 200, and a preset angle is set between the connecting plate 101 and the electrophoresis tank body 100 so that the electrophoresis tank body 100 is tilted relative to the connecting frame 200. Fig.18 As shown, a first spacing 106 is set between two adjacent connecting frames 200, and a second spacing 105 is formed between two adjacent electrophoresis tank bodies 100 according to the size of the first spacing 106, so as to avoid mutual shielding or heat generation and mutual influence, and facilitate the assembly of two adjacent electrophoresis tank bodies 100. Optionally, the second spacing 105 can also be zero, and the size of the first spacing 106 depends on the size of the first mounting plate.

[0072] In one embodiment, in order to prevent the connection between two adjacent electrophoresis tank bodies 100 from becoming detached, a first boss 2031 is provided on the two side panels forming the snap-fit ​​groove 2032, and a first notch 2021 adapted thereto is provided on the snap-fit ​​boss 202. When two adjacent electrophoresis tank bodies 100 are spliced ​​together, the first boss 2031 of the first electrophoresis tank body 100 is snap-fitted to the first notch 2021 of the second electrophoresis tank body 100, thereby further reinforcing the entire device.

[0073] Furthermore, in order to make the splicing structure of two adjacent electrophoresis tank bodies 100 more compact, the first notch 2021 is arranged along the side of the connecting frame 200. When the first boss 2031 of the connecting frame 200 of the first electrophoresis tank body 100 is snapped onto the first notch 2021 of the connecting frame 200 of the second electrophoresis tank body 100, the snap-on boss 202 of the connecting frame 200 of the second electrophoresis tank body 100 abuts against the side wall of the connecting frame 200 of the first electrophoresis tank body 100. Thus, a structure as shown in FIG. Fig.18 A first spacing 106 is shown.

[0074] In one embodiment, in order to realize the rapid connection of the circuit between two adjacent electrophoresis tank bodies 100, the connecting frame 200 is provided with a first mounting plate 203 on one side of the clamping boss 202, and the first mounting plate 203 is provided with a second terminal 2031 electrically connected to the first terminal 201 and a first clearance groove 2033 corresponding to the position of the first notch 2021. When two adjacent electrophoresis tank bodies 100 are connected, the first mounting plate 203 on the connecting frame 200 of the second electrophoresis tank body 100 abuts against the connecting frame 200 of the first electrophoresis tank body 100. In this embodiment, there are two second terminals 2031, which are respectively connected to the positive and negative poles of the power supply. Furthermore, the connecting frame 200 is provided with a first support plate 204 on one side of the snap-in groove 2032, and the first support plate 204 is provided with a first through hole 2041 adapted to the second terminal 2031. When two adjacent electrophoresis tank bodies 100 are connected, one end of the second terminal 2031 on the first mounting plate 203 of the second electrophoresis tank body 100 passes through the first through hole 2041 on the first support plate 204 of the first electrophoresis tank body 100, and the first support plate 204 is in contact with the side wall of the adjacent connecting frame 200, further supporting and positioning the two adjacent connecting frames 200, so that the splicing connection between the two is more stable. Furthermore, in order to reinforce the structure of the first mounting plate 203 and the first support plate 204, a first reinforcing rib 2032 is provided on the first mounting plate 203, and a second reinforcing rib 2042 is provided on the first support plate 204. Furthermore, in order to reduce the overall mass of the connecting frame 200 , a plurality of hollow structures 205 are provided on the connecting frame 200 .

[0075] In one embodiment, the electrophoresis device further comprises a first tank cover 400, which can be detachably arranged at the first opening of the electrophoresis tank body 100, and a plurality of wiring caps 401 are arranged on the first tank cover 400, and a pre-connected circuit is arranged between the plurality of wiring caps 401, and the plurality of wiring caps 401 are respectively plugged with the first terminal 201, the positive terminal 3021 and the negative terminal 3031 in a one-to-one correspondence, so as to realize the series connection or parallel connection of the circuit between two adjacent electrophoresis tank bodies 100, thereby realizing the rapid connection of the circuit between two adjacent electrophoresis tank bodies 100. Further, the first tank cover 400 is set to two different colors, and the first tank covers 400 of the two different colors are respectively pre-set for different circuits, for example, the black one is set to the series circuit, and the red one is set to the parallel circuit, and the operator distinguishes by the color, so that there is no need to confirm the specific connection mode of the circuit of the first tank cover 400, or the first tank cover 400 can be quickly identified as being installed correctly or incorrectly and the series circuit or parallel circuit used in the batch experiment.

[0076] In one embodiment, in order to reduce the difficulty of sealing the electrode holder 300, the electrophoresis tank body 100 is set to a single glue tank structure. Specifically, the first experimental port of the electrode holder 300 is set on one side, and there is only one, and a preset distance is set between the electrode holder 300 and the electrophoresis tank body 100, so that the glue plate 500 can be detachably set within the preset distance. As another variation of this embodiment, Fig.15 As shown, a cooling chamber 103 may also be provided to cool the entire device to prevent the electrophoresis experiment from being affected by excessive temperature.

[0077] Furthermore, if Fig.12 , Fig.13 as well as Fig.16 As shown, a first sealing groove 3015 is provided on one side of the first experimental opening of the electrode holder 300, and a first sealing strip 30151 is provided in the first sealing groove 3015. The first sealing strip 30151 partially protrudes out of the first sealing groove 3015. When the rubber plate 500 is arranged within a preset spacing, the first sealing strip 30151 is in an extruded state, thereby forming a seal of the first experimental opening, so that the first cavity 102 and the second cavity 3016 are insulated.

[0078] Furthermore, the first sealing strip 30151 can be detachably arranged on the first sealing groove 3015, and a clamping step 301511 is arranged on one side of the first sealing strip 30151 away from the bottom wall of the electrophoresis tank body 100. Since the commonly used rubber plates 500 on the market can be configured with hand-cast glue and prefabricated glue of different sizes, and the sizes of prefabricated glue and hand-cast glue include 80mm*100mm and 100mm*100mm, when the rubber plate 500 is configured with prefabricated glue or hand-cast glue of different sizes, the height of the lofting notch is inconsistent, that is, boss structures of different heights will be formed on the rubber plate 500. In order to enable the electrophoresis device to meet the needs of experiments with rubber plates 500 equipped with two different sizes of prefabricated glue or hand-cast glue, the first sealing strip 30151 is detachably arranged on the first sealing groove 3015, and ... 51 can be disassembled and set on the first sealing groove 3015, and the step structure 301511 of the first sealing strip 30151 is pre-set. When conducting experiments on the glue plate 500 equipped with prefabricated glue or hand-filled glue of different sizes, it is only necessary to replace the corresponding first sealing strip 30151. The first sealing strip 30151 is provided with two step structures 301511 of different lengths to accurately seal the glue plate 500 equipped with prefabricated glue or hand-filled glue of different sizes, thereby improving the adaptability of the electrophoresis device.

[0079] In one embodiment, in order to stably fix the electrode bracket 300 in the first cavity 102 of the electrophoresis tank body 100, as shown in FIG. Fig.11As shown, the electrophoresis tank body 100 is provided with a first clamping groove 103, and the electrode bracket 300 is provided with a first clamping boss. When the first clamping boss of the electrode bracket 300 is clamped on the first clamping groove 103 of the electrophoresis tank body 100, the side wall of the electrode bracket 300 abuts against the side wall of the electrophoresis tank body 100. Specifically, the side wall of the electrode bracket 300 where the rubber plate 500 is not installed abuts against the inner wall of the electrophoresis tank body 100, so that the electrode bracket 300 is stably installed in the electrophoresis tank body 100.

[0080] In one embodiment, Figure 14-15 As shown, in order to further support the rubber plate 500, a pressure plate 600 is arranged between the electrophoresis tank body 100 and the rubber plate 500. One side of the pressure plate 600 abuts against the rubber plate 500, and the other side of the pressure plate 600 abuts against the inner wall of the electrophoresis tank body 100. The pressure plate 600 can support the rubber plate 500. During installation, the pressure plate 600 can drive the rubber plate 500 to translate as a whole. Compared with the traditional hinged rotation to drive the pressure plate 600 to perform extrusion sealing, the overall translation makes the sealing effect of the rubber plate 500 on the first experimental port better.

[0081] Furthermore, in order to reduce the volume of the pressing plate 500, the outer structure of the pressing plate 500 is the same as the structure of the first sealing groove 3015, and the pressing plate 600 can cover the first sealing groove 3015. Specifically, the first sealing groove 3015 is a U-shaped structure, so the pressing plate 600 is set to a U-shaped structure, and only the edge of the pressing plate 600 needs to cover the edge of the first sealing strip 30151, while ensuring the sealing effect, the volume of the pressing plate 600 is reduced, and it is more convenient for operators to squeeze and seal the rubber plate 500.

[0082] Furthermore, in order to avoid the position of the pressure plate 600 from being offset, a guide column 601 is provided on the pressure plate 600, and an adaptive guide hole 3017 is provided on the electrode bracket 300, or a guide hole 3017 is provided on the pressure plate 600, and a guide column 601 is provided on the electrode bracket 300. The guide column 601 is inserted into the guide hole 3017, and the guide column 601 can move axially along the guide hole 3017, while driving the rubber plate 500 to translate and seal as a whole, it can also ensure that the position of the pressure plate 600 will not be offset.

[0083] In one embodiment, Fig.18 As shown, a plurality of electrophoresis tank bodies 100 are arranged linearly, and the actual number of the electrophoresis tank bodies 100 is preset according to experimental requirements and is not limited by the present invention, and can be 3, 4 or 5.

[0084] The above is only a preferred embodiment of the present invention. It should be noted that a person skilled in the art can make several improvements and modifications without departing from the principle of the present invention. These improvements and modifications should also be considered as the protection scope of the present invention.

Claims

1. An electrophoresis device, characterized in that include: The electrophoresis tank body has a first cavity, the electrophoresis tank body is provided with a first opening for connecting the first cavity with the outside, and the electrophoresis tank body is tilted so that there is a misalignment between two adjacent electrophoresis tank bodies; An electrode holder is disposed in the first cavity of the electrophoresis tank body, the electrode holder has a second cavity, a second opening communicating with the second cavity, and a first experimental port communicating with the second cavity, the electrode holder is provided with a positive electrode wire and a negative electrode wire, the positive electrode wire and the negative electrode wire can form a uniform electric field, the positive electrode wire portion is located outside the second cavity, and the negative electrode wire portion is located inside the second cavity; The electrode support comprises a support frame body, a positive electrode assembly and a negative electrode assembly, wherein the positive electrode assembly comprises a positive electrode support, and the negative electrode assembly comprises a negative electrode support, wherein the support frame body is provided with a first mounting groove adapted to the positive electrode support and a second mounting groove adapted to the negative electrode support, the positive electrode assembly is detachably arranged on the first mounting groove of the support frame body, and the negative electrode assembly is detachably arranged on the second mounting groove of the support frame body; A glue plate, on which prefabricated glue is provided, the glue plate is detachably arranged on the electrode bracket, and the glue plate can seal the first experimental port of the electrode bracket so that the first cavity and the second cavity are relatively independent; A connecting frame is arranged on one side of the electrophoresis tank body, and is used to connect two adjacent electrophoresis tank bodies. The connecting frame is provided with a plurality of first binding posts, and the plurality of first binding posts are respectively electrically connected to the corresponding positive electrode wires and the negative electrode wires, so that the circuits between the two adjacent electrophoresis tank bodies are connected in series or in parallel; A connecting plate is arranged between the connecting frame and the electrophoresis tank body, and a preset angle is arranged between the connecting plate and the electrophoresis tank body so that the electrophoresis tank body is inclined relative to the connecting frame.

2. The electrophoresis device according to claim 1, characterized in that: The positive electrode assembly also includes a positive electrode terminal disposed on the positive electrode bracket, and the negative electrode assembly also includes a negative electrode terminal disposed on the negative electrode bracket. The positive electrode wire is disposed on the positive electrode bracket and is electrically connected to the positive electrode terminal, and the negative electrode wire is disposed on the negative electrode bracket and is electrically connected to the negative electrode terminal.

3. The electrophoresis device according to claim 2, characterized in that: The positive electrode support is provided with a first wiring groove, the positive electrode wire includes a first insulating section and a first exposed section, the first insulating section of the positive electrode wire is located in the first wiring groove, and the first exposed section of the positive electrode wire is fixed to the positive electrode support.

4. The electrophoresis device according to claim 3, characterized in that: The negative electrode bracket is provided with a second wiring groove, the negative electrode wire includes a second insulating section and a second exposed section, the second insulating section of the negative electrode wire is located in the second wiring groove, and the second exposed section of the negative electrode wire is fixed on the negative electrode bracket, wherein the second exposed section of the negative electrode wire corresponds to the first exposed section of the positive electrode wire and is relatively parallel.

5. The electrophoresis device according to claim 4, characterized in that: The positive electrode support is provided with a first fixing structure, and the first exposed section of the positive electrode wire is fixed to the positive electrode support through the first fixing structure. The negative electrode support is provided with a second fixing structure, and the second exposed section of the negative electrode wire is fixed to the negative electrode support through the second fixing structure.

6. The electrophoresis device according to claim 4, characterized in that: The distance between the second exposed section of the negative electrode wire and the bottom wall of the electrode support is half the depth of the second cavity of the electrode support.

7. The electrophoresis device according to claim 2, characterized in that: The positive electrode wire and the positive electrode bracket are integrally arranged, and the negative electrode wire and the negative electrode bracket are integrally arranged.

8. The electrophoresis device according to claim 2, characterized in that: The connecting frame is integrally arranged with the electrophoresis tank body.

9. The electrophoresis device according to claim 2, characterized in that: The connecting frame is detachably connected to the electrophoresis tank body.

10. The electrophoresis device according to claim 8 or 9, characterized in that: The connecting frame includes a snap-in boss and a snap-in groove adapted thereto. When two adjacent electrophoresis tank bodies are connected, the snap-in boss of the connecting frame of the first electrophoresis tank body is snap-into the snap-in groove of the connecting frame of the second electrophoresis tank body, or the snap-in groove of the connecting frame of the first electrophoresis tank body is snap-into the snap-in boss of the connecting frame of the second electrophoresis tank body.

11. The electrophoresis device according to claim 10, characterized in that: The clamping groove is provided with a first boss, and the clamping boss is provided with a matching first notch. When two adjacent electrophoresis tank bodies are connected, the first boss of the first electrophoresis tank body is clamped to the first notch of the second electrophoresis tank body.

12. The electrophoresis device according to claim 11, characterized in that: The first notch is arranged along the side of the connecting frame. When the first boss of the connecting frame of the first electrophoresis tank body is clamped on the first notch of the connecting frame of the second electrophoresis tank body, the clamping boss of the connecting frame of the second electrophoresis tank body abuts against the side wall of the connecting frame of the first electrophoresis tank body.

13. The electrophoresis device according to claim 11, characterized in that: The connecting frame is provided with a first mounting plate on one side of the clamping boss, and the first mounting plate is provided with a plurality of second terminals electrically connected to the plurality of first terminals and a first clearance groove corresponding to the position of the first notch. When two adjacent electrophoresis tank bodies are connected, the first mounting plate on the connecting frame of the second electrophoresis tank body abuts against the connecting frame of the first electrophoresis tank body.

14. The electrophoresis device according to claim 13, characterized in that: The connecting frame is provided with a first support plate on one side of the snap-in groove, and the first support plate is provided with a plurality of first through holes adapted to the plurality of second terminal posts. When two adjacent electrophoresis tank bodies are connected, one end of the plurality of second terminal posts on the first mounting plate of the second electrophoresis tank body passes through the plurality of first through holes on the first support plate of the first electrophoresis tank body, and the first support plate abuts against the adjacent side wall of the connecting frame.

15. The electrophoresis device according to claim 13, characterized in that: It also includes a first slot cover, which can be removably arranged at the first opening of the electrophoresis tank body, and the first slot cover is provided with a plurality of wiring caps, and a pre-connection circuit is arranged between the plurality of wiring caps, and the plurality of wiring caps are respectively plugged into the first terminal, the positive terminal and the negative terminal in a one-to-one correspondence to realize the series or parallel connection of the circuit between two adjacent electrophoresis tank bodies.

16. The electrophoresis device according to claim 15, characterized in that: The first slot cover is provided with two different colors, and the first slot covers of the two different colors are respectively provided with different pre-connection circuits.

17. The electrophoresis device according to claim 1, characterized in that: The electrophoresis tank body is a single gel tank structure, the first experimental port of the electrode bracket is set on one side, a preset distance is set between the electrode bracket and the electrophoresis tank body, and the gel plate is detachably set within the preset distance.

18. The electrophoresis device according to claim 17, characterized in that: A first sealing groove is provided on one side of the first experimental port of the electrode bracket, a first sealing strip is provided in the first sealing groove, and the first sealing strip partially protrudes out of the first sealing groove. When the rubber plate is set within the preset interval, the first sealing strip is in an extruded state.

19. The electrophoresis device according to claim 18, characterized in that: The first sealing strip is detachably arranged on the first sealing groove, and a clamping step is arranged on a side of the first sealing strip away from the bottom wall of the electrophoresis tank body.

20. The electrophoresis device according to claim 18, characterized in that: The electrophoresis tank body is provided with a first clamping groove, and the electrode bracket is provided with a first clamping boss. When the first clamping boss of the electrode bracket is clamped on the first clamping groove of the electrophoresis tank body, the side wall of the electrode bracket abuts against the side wall of the electrophoresis tank body.

21. The electrophoresis device according to claim 20, characterized in that: A pressing plate is provided between the rubber plate and the inner wall of the electrophoresis tank. One side of the pressing plate abuts against the rubber plate, and the other side of the pressing plate abuts against the inner wall of the electrophoresis tank.

22. The electrophoresis device according to claim 21, characterized in that: The outer shape structure of the pressing plate is the same as that of the first sealing groove, and the pressing plate can cover the first sealing groove.

23. The electrophoresis device according to claim 21, characterized in that: The pressing plate is provided with a guide column, and the electrode bracket is provided with a matching guide hole, or the pressing plate is provided with a guide hole, and the electrode bracket is provided with a guide column, and the guide column is inserted into the guide hole.

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