A whitening and moisturizing skin care composition and preparation method thereof

Abstract

The present invention provides a whitening, moisturizing skin care composition and preparation method thereof, including the following raw materials: plant extract, modified ceramide, nicotinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, dipotassium glycyrrhizinate, arbutin, phenylethyl resorcinol, 4-butyl resorcinol, xanthan gum, hydroxypropyl cyclodextrin, methyl propanediol, and the balance is water; the plant extract includes one or more combinations of licorice root extract, selaginella extract, cactus extract, scutellaria root extract, peony root extract, and Lysimachia extract. The raw materials of the present invention are scientifically and rationally compounded, can effectively promote the whitening and moisturizing effect of active ingredients, reduce dullness, spots and dehydration of skin, can also resist the damage of external environment to skin, can also soften the stratum corneum of the outer layer of skin, clean the outer layer of skin, promote skin metabolism, reduce aging, and maintain the elasticity and vitality of skin.

Description

Technical Field

[0001] The present invention relates to the technical field of skin care products, and in particular to a whitening and moisturizing skin care composition and a preparation method thereof. Background Art

[0002] Skin is an important barrier for the human body to resist damage caused by external physical or chemical stimulation. When the skin is stimulated by external factors and accompanied by the aging of skin cells, the skin will have a decrease in sebum secretion, and the water retention effect will become worse and worse, resulting in dry, rough, dull skin, excessive pigmentation, causing freckles, melasma, age spots, etc. Whitening products, moisturizing and hydrating products have become one of the mainstream products of skin care products. Various whitening skin care products have appeared on the market, and many products often add a lot of chemical substances, which can cause certain damage to the skin and easily cause allergic reactions such as acne and redness. Some existing products also use safer plant extracts to improve the whitening and moisturizing effects, but the combination of plant extracts is unreasonable and the content of ingredients is low, so the whitening and moisturizing effects are weak, so the whitening and moisturizing effects are unstable, and the efficacy is also relatively single. Summary of the invention

[0003] In view of this, the present invention provides a whitening and moisturizing skin care composition and a preparation method thereof. The whitening and moisturizing skin care composition prepared by the present invention has a long-lasting and stable whitening and moisturizing effect, can effectively reduce skin pigmentation and reduce water loss, and can also clean and care for the skin to keep the skin healthy.

[0004] The technical solution of the present invention is achieved in this way:

[0005] A whitening and moisturizing skin care composition comprises the following raw materials in parts by weight:

[0006] 30-40 parts of plant extract, 8-14 parts of modified ceramide, 5-9 parts of niacinamide, 1-3 parts of magnesium ascorbyl phosphate, 1-4 parts of panthenol, 2-3 parts of lactobionic acid, 0.5-3 parts of dipalmitoyl hydroxyproline, 0.5-4 parts of dipotassium glycyrrhizinate, 5-8 parts of arbutin, 0.2-1 parts of phenylethyl resorcinol, 0.1-0.8 parts of 4-butyl resorcinol, 2-5 parts of xanthan gum, 4-9 parts of hydroxypropyl cyclodextrin, 5-8 parts of methylpropanediol, and the balance is water; the plant extract includes a combination of one or more of Glycyrrhiza glabra root extract, Selaginella extract, Opuntia cactus extract, Scutellaria baicalensis root extract, Paeonia lactiflora root extract, and Lysimachia scabra extract.

[0007] Furthermore, the whitening and moisturizing skin care composition comprises the following raw materials in parts by weight: 35 parts of plant extract, 10 parts of modified ceramide, 6 parts of niacinamide, 2 parts of magnesium ascorbyl phosphate, 2 parts of panthenol, 3 parts of lactobionic acid, 1 part of dipalmitoyl hydroxyproline, 4 parts of dipotassium glycyrrhizinate, 6 parts of arbutin, 0.5 parts of phenylethyl resorcinol, 0.4 parts of 4-butyl resorcinol, 3 parts of xanthan gum, 9 parts of hydroxypropyl cyclodextrin, 6 parts of methylpropanediol, and the balance is water.

[0008] Furthermore, the plant extract includes the following raw materials in parts by weight: 16-20 parts of Glycyrrhiza glabra root extract, 10-15 parts of Selaginella extract, 8-14 parts of Opuntia cactus extract, 7-13 parts of Scutellaria baicalensis root extract, 7-12 parts of Paeonia lactiflora root extract, and 6-10 parts of Lysimachia sibiricum extract.

[0009] Furthermore, the plant extract includes the following raw materials in parts by weight: 18 parts of Glycyrrhiza glabra root extract, 12 parts of Selaginella extract, 10 parts of Opuntia cactus extract, 9 parts of Scutellaria baicalensis root extract, 11 parts of Paeonia lactiflora root extract, and 8 parts of Lysimachia scabra extract.

[0010] Furthermore, the modified ceramide comprises the following raw materials in parts by weight: 35-50 parts of ceramide, 9-13 parts of glucosamine, 6-10 parts of glycosyl trehalose, 5-12 parts of sorbitan olivate, 9-12 parts of hydroxyethyl cellulose, and 20-30 parts of water.

[0011] Furthermore, the raw materials of ceramide include: ceramide 6Ⅱ and ceramide 3 in a mass ratio of 1 to 3:1.

[0012] Furthermore, the preparation method of the modified ceramide is: adding sorbitan olivate and hydroxyethyl cellulose into water and stirring and mixing once, then adding ceramide and stirring and mixing for a second time, and finally adding glucosamine and glycosyl trehalose and dispersing at high speed, homogenizing, and vacuum degassing to obtain the modified ceramide.

[0013] Further, the first stirring and mixing speed is 100-200 rpm, the temperature is 30-40°C, and the time is 12-16 min; the second stirring and mixing speed is 300-500 rpm, the temperature is 40-60°C, and the time is 9-11 min; the high-speed dispersion speed is 2000-3000 rpm, the temperature is 40-60°C, and the time is 3-6 min; the homogenization pressure is 120-150 MPa, the speed is 8000-10000 rpm, and the time is 2-5 min;

[0014] The preparation method of the whitening and moisturizing skin care composition comprises the following steps:

[0015] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin and methylpropylene glycol with one part of water, add plant extract and stir and mix to obtain a mixture A;

[0016] S2, after stirring and mixing the xanthan gum and the remaining water, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline and dipotassium glycyrrhizinate are added and stirred and mixed to obtain a mixture B;

[0017] S3. After mixing the mixed material A and the mixed material B obtained above, add the modified ceramide, mix and stir, disperse under high pressure, homogenize, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0018] Furthermore, in step S1, the stirring and mixing speed is 400-600 rpm, the temperature is 40-60°C, and the time is 6-8 min; in step S2, the stirring and mixing speed is 600-800 rpm, the temperature is 40-60°C, and the time is 10-14 min; in step S3, the stirring and mixing speed is 800-1000 rpm, the temperature is 40-60°C, and the time is 7-10 min; the high-speed dispersion speed is 3000-4000 rpm, the temperature is 40-60°C, and the time is 4-6 min; the homogenization pressure is 150-180 MPa, the speed is 10000-12000 rpm, and the time is 2-5 min.

[0019] The plant extracts in the present invention include one or more of Glycyrrhiza glabra root extract, Selaginella thunbergii extract, Opuntia cactus extract, Scutellaria baicalensis root extract, Paeonia lactiflora root extract, and Lysimachia sibiricum extract. Among them:

[0020] Glycyrrhiza glabra root extract: has antibacterial and anti-inflammatory, antioxidant, anti-aging, UV protection, sun protection, skin whitening and brightening, freckle removal and other effects. It can inhibit the activity of tyrosinase, dopachrome interconversion and DHICA oxidase. It is a fast, efficient and green whitening and freckle removal cosmetic additive. It has the ability to scavenge oxygen free radicals similar to SOD (superoxide dismutase) and has the ability to resist oxygen free radicals similar to vitamin E.

[0021] Selaginella (SELAGINELLA TAMARISCINA) extract: can form a protective film on the outer layer of the skin, rebuild the skin barrier, inhibit the damage of free radicals to skin cells, resist oxidation, have strong penetration into the skin, participate in and improve skin cell metabolism, enable the skin to achieve its own balance, add subsequent nutrition, provide nutrition to cells to make the skin delicate, smooth, firm and elastic, delay aging, and can also effectively inhibit the activity of multiple enzymes (such as inhibiting tyrosinase) in the process of melanin production, greatly reduce melanin production, and keep the skin white and tender from the source.

[0022] Cactus (OPUNTIA DILLENII) extract: rich in polysaccharides and water-soluble ingredients, it can increase the skin's moisturizing ability, maintain the skin's moisture balance, reduce skin dryness and roughness, and at the same time neutralize free radicals, reduce oxidative stress damage to the skin, anti-aging, improve skin's elasticity and radiance, and can also play an antibacterial and anti-inflammatory role, lighten spots, and soothe the skin.

[0023] Scutellaria baicalensis root extract: can inhibit elastase, interfere with secretion, eliminate free radicals, thereby increasing skin metabolism, increasing skin elasticity and wrinkle resistance, and anti-aging; promotes brain amide, and improves sebum to make the skin soft and smooth; can inhibit dermatitis, enhance skin resistance, and has anti-inflammatory properties; can neutralize released histamine and has the ability to prevent allergies.

[0024] Peony (PAEONIA ALBIFLORA) root extract: The active ingredient paeoniflorin has an inhibitory effect on certain pathogenic bacteria and fungi; peony extract can inhibit elastase, eliminate free radicals, inhibit the formation of nitrogen oxides, and promote the activity of tissue proteases, etc. It has the function of revitalizing the skin and anti-aging, and has relatively good moisturizing ability.

[0025] Lysimachia CHRISTINAE extract: The nutrients in Lysimachia CHRISTINAE can promote the growth of skin cells, making the skin smoother and more delicate. At the same time, Lysimachia CHRISTINAE can effectively reduce melanin, prevent sunburn, and reduce fine lines.

[0026] Compared with the prior art, the present invention has the following beneficial effects:

[0027] (1) The present invention scientifically and rationally compounds plant extracts with raw materials such as ceramide, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, dipotassium glycyrrhizinate, arbutin, phenylethyl resorcinol, 4-butyl resorcinol, etc., which can effectively promote the whitening and moisturizing effects of the active ingredients, reduce dullness, spots and water loss of the skin, and also resist damage to the skin caused by the external environment (for example: ultraviolet radiation, light, microbial pathogens, etc.), soften the stratum corneum of the outer layer of the skin, clean the outer layer of the skin, promote skin metabolism, keep the skin in a good oil balance, reduce aging, maintain the elasticity and vitality of the skin, and also have good antibacterial and anti-inflammatory effects.

[0028] (2) The present invention modifies ceramide and, through a specific process, enables ceramide with poor water solubility to be fully mixed and dispersed with other water-soluble substances and maintain the stability of their performance, which can effectively promote the penetration of ceramide into the skin, thereby enhancing the barrier function of the skin, reducing skin redness and swelling, water loss and the impact of the external environment on the skin, and effectively helping damaged skin to relieve dryness, thereby achieving a good hydrating and moisturizing effect.

[0029] (3) The present invention, under the synergistic effect of plant extracts, niacinamide, magnesium ascorbyl phosphate and panthenol, can effectively reduce the deposition of melanin, reduce facial dullness, and improve the whitening effect. At the same time, it can also effectively increase the moisture content in the skin and play a good moisturizing role.

[0030] (4) The synergistic effect of lactobionic acid, dipalmitoyl hydroxyproline and dipotassium glycyrrhizinate in the present invention can accelerate cell metabolism, speed up the shedding of melanin keratinocytes, etc., and at the same time of whitening and moisturizing, can soften the stratum corneum of the outer layer of the skin, clean the outer layer of the skin, promote the repair of skin tissue, make the skin soft, effectively prevent skin roughness, and improve the glossiness of the skin.

[0031] (5) The present invention can effectively retain the active ingredients in the plant extract through a specific preparation process, effectively improve the synergistic effect of the plant extract and other components in the raw materials, and promote the rapid absorption of the skin while improving the stability, thereby more efficiently playing the role of whitening and moisturizing. DETAILED DESCRIPTION

[0032] In order to better understand the technical content of the present invention, specific embodiments are provided below to further illustrate the present invention.

[0033] Unless otherwise specified, the experimental methods used in the embodiments of the present invention are all conventional methods.

[0034] Unless otherwise specified, the materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial sources.

[0035] Example 1

[0036] The proportions of the various raw materials in this embodiment are as follows:

[0037]

[0038]

[0039]

[0040] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 2:1;

[0041] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 15 minutes at a speed of 200 rpm and a temperature of 40° C., ceramide is added and stirred and mixed for a second time at a speed of 500 rpm and a temperature of 50° C. for 11 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 2500 rpm and a temperature of 50° C. for 5 minutes, homogenized at a pressure of 150 MPa and a speed of 9000 rpm for 3 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0042] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0043] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropanediol and one part of water at a speed of 400 rpm and a temperature of 60° C. for 7 minutes, add plant extract and stir and mix at a speed of 400 rpm and a temperature of 60° C. for 6 minutes to obtain a mixture A;

[0044] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 10 min, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 8 min to obtain a mixture B;

[0045] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 1000 rpm and a temperature of 50°C for 9 minutes, add the modified ceramide and stir and mix at a rotation speed of 1000 rpm and a temperature of 50°C for 8 minutes, then disperse under high pressure at a rotation speed of 3000 rpm and a temperature of 50°C for 5 minutes, homogenize at 170 MPa and a rotation speed of 12000 rpm for 4 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0046] Example 2

[0047] The proportions of the various raw materials in this embodiment are as follows:

[0048]

[0049]

[0050]

[0051]

[0052] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 2:1;

[0053] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 12 minutes at a speed of 100 rpm and a temperature of 30° C., ceramide is added and stirred and mixed for a second time at a speed of 400 rpm and a temperature of 40° C. for 10 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 3000 rpm and a temperature of 40° C. for 4 minutes, homogenized at a pressure of 120 MPa and a speed of 8000 rpm for 2 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0054] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0055] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropanediol and one part of water at a speed of 600 rpm and a temperature of 50° C. for 6 minutes, add plant extract and stir and mix at a speed of 600 rpm and a temperature of 50° C. for 8 minutes to obtain a mixture A;

[0056] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 600 rpm and a temperature of 50° C. for 14 minutes, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 600 rpm and a temperature of 50° C. for 8 minutes to obtain a mixture B;

[0057] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 800 rpm and a temperature of 40°C for 8 minutes, add modified ceramide and stir and mix at a rotation speed of 800 rpm and a temperature of 40°C for 10 minutes, then disperse under high pressure at a rotation speed of 4000 rpm and a temperature of 40°C for 4 minutes, homogenize at 160 MPa and a rotation speed of 10000 rpm for 3 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0058] Example 3

[0059] The proportions of the various raw materials in this embodiment are as follows:

[0060]

[0061]

[0062]

[0063] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 1:1;

[0064] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 16 minutes at a speed of 150 rpm and a temperature of 35° C., ceramide is added and stirred and mixed for a second time at a speed of 350 rpm and a temperature of 60° C. for 9 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 2000 rpm and a temperature of 60° C. for 3 minutes, homogenized at a pressure of 130 MPa and a speed of 10000 rpm for 5 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0065] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0066] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropanediol and one part of water at a speed of 500 rpm and a temperature of 40° C. for 7 minutes, add plant extract and stir and mix at a speed of 500 rpm and a temperature of 40° C. for 8 minutes to obtain a mixture A;

[0067] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 800 rpm and a temperature of 40° C. for 12 minutes, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 800 rpm and a temperature of 40° C. for 7 minutes to obtain a mixture B;

[0068] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 900 rpm and a temperature of 60°C for 7 minutes, add the modified ceramide and stir and mix at a rotation speed of 900 rpm and a temperature of 60°C for 9 minutes, then disperse under high pressure at a rotation speed of 3500 rpm and a temperature of 60°C for 5 minutes, homogenize at 150 MPa and a rotation speed of 11000 rpm for 5 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0069] Example 4

[0070] The proportions of the various raw materials in this embodiment are as follows:

[0071]

[0072]

[0073]

[0074]

[0075] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 3:1;

[0076] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 13 minutes at a speed of 180 rpm and a temperature of 35° C., ceramide is added and stirred and mixed for a second time at a speed of 300 rpm and a temperature of 45° C. for 10 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 2000 rpm and a temperature of 45° C. for 6 minutes, homogenized at a pressure of 140 MPa and a speed of 10000 rpm for 4 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0077] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0078] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropanediol and one part of water at a speed of 550 rpm and a temperature of 50° C. for 6 minutes, add plant extract and stir and mix at a speed of 550 rpm and a temperature of 40° C. for 8 minutes to obtain a mixture A;

[0079] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 650 rpm and a temperature of 45° C. for 13 minutes, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 650 rpm and a temperature of 45° C. for 8 minutes to obtain a mixture B;

[0080] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 900 rpm and a temperature of 50°C for 10 minutes, add the modified ceramide and stir and mix at a rotation speed of 900 rpm and a temperature of 60°C for 7 minutes, then disperse under high pressure at a rotation speed of 4000 rpm and a temperature of 60°C for 6 minutes, homogenize at 180 MPa and a rotation speed of 12000 rpm for 2 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0081] Comparative Example 1

[0082] The difference between this comparative example and Example 1 is that the raw material ratios of the whitening and moisturizing skin care composition in this comparative example are different; the raw materials in this comparative example are as follows:

[0083]

[0084]

[0085]

[0086] Comparative Example 2

[0087] The difference between this comparative example and Example 1 is that this comparative example does not contain plant extracts; the raw materials of this comparative example are as follows:

[0088]

[0089]

[0090] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 2:1;

[0091] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 15 minutes at a speed of 200 rpm and a temperature of 40° C., ceramide is added and stirred and mixed for a second time at a speed of 500 rpm and a temperature of 50° C. for 11 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 2500 rpm and a temperature of 50° C. for 5 minutes, homogenized at a pressure of 150 MPa and a speed of 9000 rpm for 3 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0092] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0093] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropylene glycol and one part of water at a speed of 400 rpm and a temperature of 60° C. for 7 minutes to obtain a mixture A;

[0094] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 10 min, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 8 min to obtain a mixture B;

[0095] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 1000 rpm and a temperature of 50°C for 9 minutes, add the modified ceramide and stir and mix at a rotation speed of 1000 rpm and a temperature of 50°C for 8 minutes, then disperse under high pressure at a rotation speed of 3000 rpm and a temperature of 50°C for 5 minutes, homogenize at 170 MPa and a rotation speed of 12000 rpm for 4 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0096] Comparative Example 3

[0097] The difference between this comparative example and Example 1 is that this comparative example does not contain niacinamide, magnesium ascorbyl phosphate, and panthenol; the raw materials of this comparative example are as follows:

[0098]

[0099]

[0100]

[0101] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 2:1;

[0102] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 15 minutes at a speed of 200 rpm and a temperature of 40° C., ceramide is added and stirred and mixed for a second time at a speed of 500 rpm and a temperature of 50° C. for 11 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 2500 rpm and a temperature of 50° C. for 5 minutes, homogenized at a pressure of 150 MPa and a speed of 9000 rpm for 3 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0103] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0104] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropylene glycol and one part of water at a speed of 400 rpm and a temperature of 60° C. for 7 minutes to obtain a mixture A;

[0105] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 10 min, lactobionic acid, dipalmitoyl hydroxyproline and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 8 min to obtain a mixture B;

[0106] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 1000 rpm and a temperature of 50°C for 9 minutes, add the modified ceramide and stir and mix at a rotation speed of 1000 rpm and a temperature of 50°C for 8 minutes, then disperse under high pressure at a rotation speed of 3000 rpm and a temperature of 50°C for 5 minutes, homogenize at 170 MPa and a rotation speed of 12000 rpm for 4 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0107] Comparative Example 4

[0108] The difference between this comparative example and Example 1 is that this comparative example does not contain lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate; the raw materials of this comparative example are as follows:

[0109]

[0110]

[0111]

[0112] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 2:1;

[0113] The preparation method of the modified ceramide of this embodiment is as follows: sorbitan olivate and hydroxyethyl cellulose are added to water and stirred and mixed for 15 minutes at a speed of 200 rpm and a temperature of 40° C., ceramide is added and stirred and mixed for a second time at a speed of 500 rpm and a temperature of 50° C. for 11 minutes, and finally glucosamine and glycosyl trehalose are added and dispersed at a speed of 2500 rpm and a temperature of 50° C. for 5 minutes, homogenized at a pressure of 150 MPa and a speed of 9000 rpm for 3 minutes, and vacuum degassing is performed to obtain the modified ceramide;

[0114] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0115] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropanediol and one part of water at a speed of 400 rpm and a temperature of 60° C. for 7 minutes, add plant extract and stir and mix at a speed of 400 rpm and a temperature of 60° C. for 6 minutes to obtain a mixture A;

[0116] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 10 min, niacinamide, magnesium ascorbyl phosphate and panthenol are added and stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 8 min to obtain a mixture B;

[0117] S3. After stirring and mixing the above-obtained mixed material A and the above-obtained mixed material B at a rotation speed of 1000 rpm and a temperature of 50°C for 9 minutes, add the modified ceramide and stir and mix at a rotation speed of 1000 rpm and a temperature of 50°C for 8 minutes, then disperse under high pressure at a rotation speed of 3000 rpm and a temperature of 50°C for 5 minutes, homogenize at 170 MPa and a rotation speed of 12000 rpm for 4 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0118] Comparative Example 5

[0119] The difference between this comparative example and Example 1 is that the modified ceramide is replaced by ceramide in this comparative example; the raw materials of this comparative example are as follows:

[0120]

[0121]

[0122] Ceramide is composed of ceramide 6Ⅱ and ceramide 3 in a mass ratio of 2:1;

[0123] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0124] S1. Divide water into two parts, stir and mix hydroxypropyl cyclodextrin, methylpropanediol and one part of water at a speed of 400 rpm and a temperature of 60° C. for 7 minutes, add plant extract and stir and mix at a speed of 400 rpm and a temperature of 60° C. for 6 minutes to obtain a mixture A;

[0125] S2, after the xanthan gum and the remaining water are stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 10 min, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate are added and stirred and mixed at a speed of 700 rpm and a temperature of 60° C. for 8 min to obtain a mixture B;

[0126] S3. Stir and mix the mixed material A and the mixed material B obtained above at a rotation speed of 1000 rpm and a temperature of 50°C for 9 minutes, then add ceramide and stir and mix at a rotation speed of 1000 rpm and a temperature of 50°C for 8 minutes, then disperse under high pressure at a rotation speed of 3000 rpm and a temperature of 50°C for 5 minutes, homogenize at 170 MPa and a rotation speed of 12000 rpm for 4 minutes, and perform vacuum degassing to obtain a whitening and moisturizing skin care composition.

[0127] Comparative Example 6

[0128] The difference between this comparative example and Example 1 is that: the preparation method of the modified ceramide in this comparative example is different;

[0129] The preparation method of the modified ceramide in this comparative example is as follows: ceramide, glucosamine, glycosyl trehalose, sorbitan olivate and hydroxyethyl cellulose are added into water, stirred and mixed at a speed of 200 rpm and a temperature of 40° C. for 26 min, then homogenized at a pressure of 150 MPa and a speed of 9000 rpm for 3 min, and vacuum degassed to obtain the modified ceramide.

[0130] Comparative Example 7

[0131] The difference between this comparative example and Example 1 is that: the preparation method of the whitening and moisturizing skin care composition in this comparative example is different;

[0132] The preparation method of the whitening and moisturizing skin care composition of this embodiment comprises the following steps:

[0133] Plant extract, modified ceramide, niacinamide, magnesium ascorbyl phosphate, panthenol, lactobionic acid, dipalmitoyl hydroxyproline, dipotassium glycyrrhizinate, xanthan gum, hydroxypropyl cyclodextrin and methylpropanediol are added to water, stirred and mixed at a speed of 1000 rpm and a temperature of 50°C for 20 minutes, then dispersed under high pressure at a speed of 3000 rpm and a temperature of 50°C for 5 minutes, homogenized at 170 MPa and a speed of 12000 rpm for 4 minutes, and vacuum degassed to obtain a whitening and moisturizing skin care composition.

[0134] Experimental situation

[0135] The whitening and moisturizing skin care compositions prepared in Examples 1-4 and Comparative Examples 1-7 of the present invention were subjected to performance testing experiments, and the experimental results are as follows:

[0136] 1. Stability test

[0137] 1.1 Heat resistance

[0138] 20 g of the whitening and moisturizing skin care compositions prepared in Examples 1 to 4 of the present invention and Comparative Examples 1 to 7 were respectively put into glass bottles, tightly capped and sealed, and then left to stand at 40° C. for 24 hours, returned to room temperature, and observed whether impurities or stratification appeared.

[0139] 1.2 Cold resistance

[0140] 20 g of the whitening and moisturizing skin care compositions prepared in Examples 1 to 4 of the present invention and Comparative Examples 1 to 7 were respectively put into glass bottles, tightly capped and sealed, and then left to stand at -15°C for 24 hours, returned to room temperature, and observed whether impurities and stratification appeared.

[0141] 1.3 Centrifugal stability

[0142] The whitening and moisturizing skin care compositions prepared in Examples 1 to 4 of the present invention and Comparative Examples 1 to 7 were centrifuged at a speed of 2000 r / min for 30 minutes to observe whether impurities and stratification were present.

[0143] Table 1 Stability test results

[0144]

[0145]

[0146] As shown in Table 1, Examples 1 to 4 of the present invention are prepared by scientific and reasonable raw material ratios and preferred processes, so that the prepared whitening and moisturizing skin care compositions have good stability. Comparative Examples 1 to 4 have different raw material ratios, or the lack of some components has little effect on the stability of the product; Comparative Example 5 does not effectively modify ceramide and the modification process of Comparative Example 6 is unreasonable, resulting in ceramide not being able to be evenly dispersed with other ingredients, resulting in stratification; Comparative Example 7 has an unreasonable preparation process for the whitening and moisturizing skin care composition, resulting in the raw material components not being able to be evenly dispersed, the stability is reduced, and stratification occurs.

[0147] 2. Stimulation Experiment

[0148] 55 white guinea pigs were taken and divided into 11 groups, with 5 in each group, corresponding to Examples 1 to 4 and Comparative Examples 1 to 7 respectively; before the experiment, the guinea pigs were adapted for 3 days, and then the hair in the 2.5×2.5 cm area on the left and right sides of the spine of the guinea pig's back was removed as the experimental area, without damaging the epidermis of the guinea pig, and then 0.5 g of the whitening and moisturizing skin care composition prepared in the corresponding group was applied to one side of the guinea pig every day, and the same amount of glycerin was applied to the other side as a control, fixed with gauze and tape, applied once a day, and applied continuously for 14 days to observe whether erythema, eschar, and edema appeared. The hair in the test area was removed before applying every day, and the daily score was statistically calculated according to the following table, and finally the scores of each group for 14 days were accumulated and statistically calculated as the total score.

[0149] Table 2 Scoring criteria for irritation test

[0150] Erythema and eschar score Edema score No erythema 0 No edema 0 Mild erythema 1 Mild edema 1 Obvious erythema 2 Mild edema 2 Moderate or mild erythema 3 Moderate edema 3 Severe erythema to mild eschar formation 4 Moderate edema 4

[0151] Table 3 Irritation test results

[0152]

[0153]

[0154] As can be seen from Table 3, the raw materials used in the present invention are non-irritating to the skin, have a mild and non-irritating effect, and are highly safe.

[0155] 3. Whitening and moisturizing experiment

[0156] 3.1 Tyrosinase inhibition rate

[0157] With reference to the "Cosmetics-Tyrosinase Activity Inhibition Test Method (T / SHRHO15-2018)", the tyrosinase inhibition rate (%) of the whitening and moisturizing skin care compositions prepared in Examples 1 to 4 and Comparative Examples 1 to 7 was determined respectively. The test results are shown in Table 4 below.

[0158] 3.2 Free radical scavenging rate

[0159] Referring to the "Cosmetics-Free Radical (DPPH) Scavenging Test Method (T / SHRH006-2018)", the free radical scavenging rates (%) of the whitening and moisturizing skin care compositions prepared in Examples 1 to 4 and Comparative Examples 1 to 7 were respectively measured, and the test results are shown in Table 4 below.

[0160] 3.3 Moisturizing effect

[0161] The whitening and moisturizing skin care compositions prepared in Examples 1 to 4 and Comparative Examples 1 to 7 were used as experimental samples, and 5.00 g of the sample of each group was weighed, and the weight at this time was recorded as m0. Then, they were placed in an environment with a relative humidity of 40% for 24 hours, and weighed again. The mass at this time was recorded as m1. The weight of each group was counted, and the moisturizing rate (%) was calculated.

[0162] Moisture retention rate (%) = m1 / m0×100%

[0163] Table 4 Experimental results of whitening and moisturizing effects

[0164]

[0165]

[0166] As can be seen from Table 4, the whitening and moisturizing skin care compositions prepared in Examples 1 to 4 of the present invention have good whitening, anti-oxidation and moisturizing effects. Compared with Example 1, the raw material ratios in Comparative Example 1 are different, Comparative Example 2 does not contain plant extracts, Comparative Example 3 does not contain niacinamide, magnesium ascorbyl phosphate, and panthenol, Comparative Example 4 does not contain lactobionic acid, dipalmitoyl hydroxyproline, and dipotassium glycyrrhizinate, and Comparative Example 5 replaces modified ceramide with ceramide, and the preparation method of the modified ceramide in Comparative Example 6 is different. The preparation method of the whitening and moisturizing skin care composition in Comparative Example 7 is different. Due to unreasonable raw material ratios or different preparation processes, the performance of the prepared whitening and moisturizing skin care compositions is reduced. The present invention is scientifically compounded with plant extracts and raw materials such as ceramide and niacinamide, and is prepared using a specific process, which can synergistically enhance the effect of whitening and moisturizing.

[0167] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A whitening and moisturizing skin care composition, characterized in that: The invention comprises the following raw materials in parts by weight: 30-40 parts of plant extract, 8-14 parts of modified ceramide, 5-9 parts of niacinamide, 1-3 parts of magnesium ascorbyl phosphate, 1-4 parts of panthenol, 2-3 parts of lactobionic acid, 0.5-3 parts of dipalmitoyl hydroxyproline, 0.5-4 parts of dipotassium glycyrrhizinate, 5-8 parts of arbutin, 0.2-1 parts of phenethyl resorcinol, 0.1-0.8 parts of 4-butyl resorcinol, 2-5 parts of xanthan gum, 4-9 parts of hydroxypropyl cyclodextrin, 5-8 parts of methylpropanediol, 150-200 parts of water; The plant extract comprises a combination of one or more of a root extract of Glycyrrhiza glabra, a Selaginella extract, a cactus extract, a root extract of Scutellaria baicalensis, a root extract of Paeonia lactiflora, and a Lysimachia sibiricum extract; the modified ceramide comprises the following raw materials in parts by weight: 35-50 parts of ceramide, 9-13 parts of glucosamine, 6-10 parts of glycosyl trehalose, 5-12 parts of sorbitan olivate, 9-12 parts of hydroxyethyl cellulose, and 20-30 parts of water; the preparation method of the modified ceramide comprises the following steps: adding sorbitan olivate and hydroxyethyl cellulose into water, stirring and mixing once, then adding ceramide, stirring and mixing twice, and finally adding glucosamine and glycosyl trehalose, dispersing at high speed, homogenizing, and vacuum degassing to obtain the modified ceramide.

2. The whitening and moisturizing skin care composition according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 35 parts of plant extract, 10 parts of modified ceramide, 6 parts of niacinamide, 2 parts of magnesium ascorbyl phosphate, 2 parts of panthenol, 3 parts of lactobionic acid, 1 part of dipalmitoyl hydroxyproline, 4 parts of dipotassium glycyrrhizinate, 6 parts of arbutin, 0.5 parts of phenylethyl resorcinol, 0.4 parts of 4-butyl resorcinol, 3 parts of xanthan gum, 9 parts of hydroxypropyl cyclodextrin, 6 parts of methylpropanediol and 150 parts of water.

3. The whitening and moisturizing skin care composition according to claim 1, characterized in that: The plant extract comprises the following raw materials in parts by weight: 16-20 parts of Glycyrrhiza glabra root extract, 10-15 parts of Selaginella extract, 8-14 parts of Opuntia cactus extract, 7-13 parts of Scutellaria baicalensis root extract, 7-12 parts of Paeonia lactiflora root extract, and 6-10 parts of Lysimachia sibiricum extract.

4. The whitening and moisturizing skin care composition according to claim 1, characterized in that: The raw materials of the ceramide include: ceramide 6 II and ceramide 3 in a mass ratio of 1-3:

1.

5. The whitening and moisturizing skin care composition according to claim 1, characterized in that: The first stirring and mixing speed is 100-200 rpm, the temperature is 30-40°C, and the time is 12-16 min; the second stirring and mixing speed is 300-500 rpm, the temperature is 40-60°C, and the time is 9-11 min; the high-speed dispersion speed is 2000-3000 rpm, the temperature is 40-60°C, and the time is 3-6 min; the homogenization pressure is 120-150 MPa, the speed is 8000-10000 rpm, and the time is 2-5 min.

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