A shock wave guide system

Abstract

The present invention relates to a shock wave catheter system, comprising a catheter assembly, a balloon, and an electrode pair. The catheter assembly comprises an outer catheter, an intermediate catheter, and an inner catheter. The intermediate catheter is arranged in the outer catheter, and the distal end thereof extends out of the distal end of the outer catheter. The intermediate catheter is provided with a plurality of holes, and the plurality of holes are distributed along the length direction thereof. The inner catheter is arranged in the intermediate catheter, and can be moved in the length direction of the intermediate catheter. The balloon is connected between the distal end of the outer catheter and the distal end of the intermediate catheter. Only one pair of electrodes is provided, which are arranged on the inner catheter. When the inner catheter is moved, the electrode pair can be exposed from the hole of the intermediate catheter. The system of the present invention only needs one electrode pair, and can realize shock wave treatment of long lesions in combination with a long balloon. The number of wires is small, the outer diameter of the entire catheter is small, and the smooth arrival of the catheter is not affected for smaller lesion sites. The structure of the entire system is simple, the processing is convenient, and the operation and use are very flexible.

Description

Technical Field

[0001] The invention belongs to the technical field of medical devices, and in particular relates to a shock wave catheter system. Background Art

[0002] The shock wave catheter system is a medical device used to treat vascular calcification. The working principle of the shock wave catheter system is that the electrodes in the balloon filled with a conductive medium discharge to form cavitation bubbles and then generate shock waves, which impact the calcified area and break up the calcified lesions.

[0003] For long lesions occurring in peripheral blood vessels, the maximum length of existing shock wave balloon specifications cannot meet the clinical needs of long lesions. Simply increasing the balloon length and adding electrode pairs will lead to an increase in the number of wires inside the catheter. Too many wires will cause the outer diameter of the catheter to be too large. When used in certain lesions in smaller blood vessels, the catheter needs to enter the blood vessels, and a catheter with an outer diameter that is too large cannot reach the lesion site smoothly.

[0004] Referring to the patent publication number CN220001861U, a shock wave balloon catheter for stenotic lesions is disclosed, which is provided with not only two balloons but also multiple sets of first electrode pairs and second electrode pairs. The more electrode pairs there are, the more the number of internal wires will inevitably increase, resulting in an excessively large outer diameter of the catheter and a more complicated catheter structure.

[0005] In addition, see patent publication number CN114886503A for a shock wave balloon catheter based on tip discharge, patent publication number CN215899865U for a shock wave balloon catheter system with controllable discharge, and patent publication number CN113349882A for a shock wave generating system. Although multiple electrode pairs are provided to meet the treatment of long lesions, they all have the problems of large outer diameter of the catheter and complex structure. Summary of the invention

[0006] The purpose of the present invention is to provide a shock wave catheter system suitable for the treatment of cardiovascular stenosis.

[0007] In order to achieve the above object, the technical solution adopted by the present invention is:

[0008] A shock wave guide system, comprising:

[0009] Catheter assembly: The catheter assembly comprises an outer catheter, an intermediate catheter and an inner catheter. The intermediate catheter is inserted into the outer catheter, and the distal end of the intermediate catheter extends out of the distal end of the outer catheter. The intermediate catheter is provided with a plurality of holes, and the plurality of holes are distributed along the length direction of the intermediate catheter. The inner catheter is inserted into the intermediate catheter, and the inner catheter can move in the length direction of the intermediate catheter.

[0010] Balloon: the proximal end of the balloon is connected to the distal end of the outer catheter, and the distal end of the balloon is connected to the distal end of the intermediate catheter;

[0011] Electrode pair: The electrode pair is only one pair, and the electrode pair is arranged on the inner catheter. By moving the inner catheter, the electrode pair can be exposed from the hole of the middle catheter.

[0012] Preferably, in the above technical solution, a medium channel is formed between the outer catheter and the middle catheter, and a conductive medium is injected into the balloon through the medium channel; when the balloon is filled with the conductive medium, conductive breakdown occurs between the electrode pairs exposed from the holes to form a shock wave.

[0013] Preferably, the above technical solution comprises a first electrode and a second electrode, one of the first electrode and the second electrode is used to connect to the positive electrode of a power source, and the other is used to connect to the negative electrode of the power source, and the first electrode and the second electrode are annularly sleeved on the outer circumference of the inner catheter, and the annular first electrode and the second electrode can be exposed from holes at different angles, and the structure is simple and convenient to align with the hole before exposure.

[0014] Further preferably, the hole comprises a first hole and a second hole, the first hole is used to expose the first electrode, and the second hole is used to expose the second electrode, so that the discharge between the first electrode and the second electrode is more controllable.

[0015] Further preferably, the outer surface of the electrode pair does not protrude from the outer surface of the inner conduit, which can reduce the gap between the intermediate conduit and the inner conduit and avoid the conductive medium from flowing from the hole into the space between the intermediate conduit and the inner conduit as much as possible.

[0016] Preferably, in the above technical solution, two adjacent holes are staggered in the circumferential direction of the intermediate catheter, and the staggered angle is 30°-180°, such as 30°, 45°, 60°, 90°, 120°, 150°, 180°, etc., which can meet the discharge treatment at different angles without rotating the catheter assembly.

[0017] Further preferably, all two adjacent holes are staggered at the same angle in the circumferential direction of the intermediate conduit.

[0018] Preferably, in the above technical solution, the hole is located on the middle catheter inside the balloon.

[0019] In the above technical solution, preferably, the gap between the intermediate conduit and the inner conduit does not exceed 0.2 mm, such as 0.15 mm, 0.1 mm, etc., which will not affect the movement of the inner conduit in the intermediate conduit on the one hand, and on the other hand, avoid the conductive medium from flowing from the hole into the space between the intermediate conduit and the inner conduit as much as possible.

[0020] Preferably, in the above technical solution, the system further comprises a handle, wherein the handle is connected to the proximal end of the outer catheter, a mobile driving mechanism is arranged in the handle, and the mobile driving mechanism is connected to the inner catheter for driving the inner catheter to move.

[0021] Further preferably, the mobile driving mechanism includes a power component, a push rod, and a slider. The power component is transmission-connected to the push rod for driving the push rod to rotate around its own axis. The slider is threadedly connected to the push rod, and the slider is restricted to move only along the push rod. The inner catheter is connected to the slider.

[0022] Preferably, in the above technical solution, the system further comprises an energy generator, and the energy generator is connected to the electrode pair.

[0023] Further preferably, the energy generator has a detection mode and a discharge mode. In the detection mode: the energy generator determines whether the electrode pair is exposed from the hole; in the discharge mode: the energy generator provides a discharge voltage / current to the electrode pair. By judging the position of the electrode pair, if the electrode pair is not accurately exposed from the hole, it is impossible to switch to the discharge mode, thereby avoiding affecting the accuracy of the discharge.

[0024] More preferably, when the energy generator determines whether the electrode pair is exposed from the hole, it includes sending an AC signal of a set frequency to detect the impedance of the electrode pair. When the impedance of the electrode pair is less than the set impedance value, it is determined that the electrode pair is exposed from the hole, or is accurately exposed. The set frequency is 1kHz~100kHz, and the set impedance value is less than 1kΩ.

[0025] Still further preferably, the energy generator is provided with a detection circuit, and the detection circuit is used to detect the impedance of the electrode pair and / or to detect the discharge current, and the detection circuit comprises a sampling module, a first-stage amplifier, a second-stage amplifier, and a digital-to-analog conversion module, and the sampling module, the first-stage amplifier, the second-stage amplifier, and the digital-to-analog conversion module are connected in series in sequence.

[0026] Still further preferably, the secondary amplifier comprises a first secondary amplifier and a second secondary amplifier, the first secondary amplifier and the second secondary amplifier are connected in parallel, the first secondary amplifier is used to amplify the impedance signal in the detection mode, and the second secondary amplifier is used to attenuate the current signal in the discharge mode, the amplification factor of the first secondary amplifier is 10 to 20 times, and the amplification factor of the second secondary amplifier is 1 / 10 to 1 / 20 times, which is equivalent to an attenuation factor of 10 to 20 times.

[0027] Still further preferably, in the discharge mode, when the discharge current reaches a set current value, the energy generator stops providing the discharge current to the electrode pair, and the set current value is 100A~200A, so as to more accurately control the output of shock wave energy.

[0028] Further preferably, the energy generator is provided with an electrode selection circuit, the electrode selection circuit comprises a first switching device, a second switching device, a third switching device and a fourth switching device, the first switching device and the second switching device are connected in series to form a first path, the third switching device and the fourth switching device are connected in series to form a second path, the first path and the second path are connected in parallel to a power supply or a signal source, the first electrode of the electrode pair is connected between the first switching device and the second switching device, the second electrode of the electrode pair is connected between the third switching device and the fourth switching device, and the electrode selection circuit can change the polarity of the first electrode and the second electrode, reduce the loss of the electrode pair caused by discharge, and ensure the discharge accuracy.

[0029] More preferably, the first path and the second path are connected in parallel and switched between the power source or the signal source through a switch device or a relay.

[0030] More preferably, the first switching device, the second switching device, the third switching device and the fourth switching device are selected from any one of IGBT and MOSFET.

[0031] Due to the application of the above technical solution, the present invention has the following advantages compared with the prior art:

[0032] The system of the present invention only requires one electrode pair, which can be used in conjunction with a long balloon to achieve shock wave treatment of long lesions. The number of wires is small, the outer diameter of the entire catheter is small, and the smooth arrival of the catheter is not affected for smaller lesions. The entire system has a simple structure, is easy to process, and is very flexible in operation and use. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Attached Figure 1 is a schematic diagram of a shock wave guide tube system of the present invention;

[0034] Attached Figure 2 is a schematic diagram of the catheter assembly of the present invention when showing the inner catheter and the electrode pair;

[0035] Attached Figure 3 is a schematic diagram of the catheter assembly of the present invention without showing the inner catheter and the electrode pair;

[0036] Attached Figure 4 is a schematic diagram of the inner catheter and the electrode pair in the present invention;

[0037] Attached Figure 5 is a schematic diagram of the mobile driving mechanism in the present invention;

[0038] Attached Figure 6 is a schematic diagram of a detection circuit in the present invention;

[0039] Attached Figure 7 is a schematic diagram of an electrode selection circuit in the present invention;

[0040] Attached Figure 8 This is a schematic diagram of the fusion of the detection circuit and the electrode selection circuit in the present invention.

[0041] In the above attached figure:

[0042] 100, external catheter;

[0043] 101, intermediate conduit; 1010, hole; 1010a, first hole; 1010b, second hole;

[0044] 102. Inner catheter;

[0045] 103, handle; 1030, medium connection port; 1031, guidewire cavity connection port; 1032, connector;

[0046] 104, medium channel;

[0047] 1050, power component; 1051, push rod; 1052, slider;

[0048] 11. Balloon;

[0049] 12. electrode pair; 120. first electrode; 121. second electrode;

[0050] 2. Energy generator;

[0051] 20. Connect cables;

[0052] 210, sampling module; 211, primary amplifier; 2120, first secondary amplifier; 2121, second secondary amplifier; 213, digital-to-analog conversion module;

[0053] 220, a first switching device; 221, a second switching device; 222, a third switching device; 223, a fourth switching device. DETAILED DESCRIPTION

[0054] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0055] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0056] like Figure 1 The shock wave guide tube system shown in the figure comprises a shock wave guide tube and an energy generator 2. Among them:

[0057] like Figure 2 , Figure 3 As shown: the shock wave catheter includes a catheter assembly 10, a balloon 11, and an electrode pair 12, which are described in detail below.

[0058] The catheter assembly includes an outer catheter 100, an intermediate catheter 101, an inner catheter 102 and a handle 103. The outer catheter 100 is located at the outermost part of the catheter assembly, the intermediate catheter 101 is located in the middle of the catheter assembly, the inner catheter 102 is located at the innermost part of the catheter assembly, and the handle 103 is connected to the proximal end of the outer catheter 100. The material of the outer catheter 100, the intermediate catheter 101 and the inner catheter 102 can be selected from Pebax, FEP, nylon, polyimide or PTFE. Specifically:

[0059] The intermediate catheter 101 is inserted into the outer catheter 100, and the distal end of the intermediate catheter 101 extends out of the distal end of the outer catheter 100, the proximal end of the balloon 11 is connected to the distal end of the outer catheter 100, and the distal end of the balloon 11 is connected to the distal end of the intermediate catheter 101, so that a medium channel 104 can be formed between the outer catheter 100 and the intermediate catheter 101, and the conductive medium is injected into the balloon 11 through the medium channel 104. In this embodiment: a plurality of holes 1010 are provided on the intermediate conduit 101, and more specifically: the holes 1010 are located on the intermediate conduit 101 inside the balloon 11, and the plurality of holes 1010 are distributed along the length direction of the intermediate conduit 101. Preferably, two adjacent holes 1010 are staggered in the circumferential direction of the intermediate conduit 101, and the staggered angle is 30°-180°, such as 30°, 45°, 60°, 90°, 120°, 150°, 180°, etc. Preferably, all two adjacent holes 1010 are staggered in the circumferential direction of the intermediate conduit 101 by the same angle, such as 90°. It can also be said that the holes 1010 are spirally distributed in the length direction of the intermediate conduit 101. The shape of the hole 1010 can be a circular hole, an elliptical hole, a square hole, an annular hole, etc.

[0060] The inner catheter 102 is inserted into the middle catheter 101, and the inner catheter 102 can move in the length direction of the middle catheter 101. The gap between the middle catheter 101 and the inner catheter 102 does not exceed 0.2mm, such as 0.15mm, 0.1mm, etc., or the gap between the two is matched, which will not affect the movement of the inner catheter 102 in the middle catheter 101 on the one hand, and avoid the conductive medium from flowing from the hole 1010 to between the middle catheter 101 and the inner catheter 102 as much as possible on the other hand, but it cannot be too tight to make it unable to move. It is worth noting that the influx of a small amount of conductive medium will not affect the normal use of the catheter assembly. The interior of the inner catheter 102 includes a lumen, such as a guidewire lumen, a guide wire lumen, etc.

[0061] The handle 103 is used to operate the catheter assembly on one hand, and is used to connect the energy generator 2 on the other hand. The handle 103 is provided with a medium connection port 1030 communicating with the medium channel 104, a guidewire cavity connection port 1031 communicating with the guidewire cavity on the inner catheter 102, and a connector 1032 communicating with the wire cavity on the inner catheter 102, through which the energy generator 2 can be connected. A mobile drive mechanism is provided in the handle 103, and the mobile drive mechanism is connected to the inner catheter 102, and is used to drive the inner catheter 102 to move in the intermediate catheter 101.

[0062] In one implementation of this embodiment: Figure 5As shown: the mobile driving mechanism includes a power component 1050, a push rod 1051, and a slider 1052. Among them, the power component 1050 can be an electric motor, etc., and the power component 1050 is connected to the push rod 1051 in a transmission manner, and is used to drive the push rod 1051 to rotate around its own axis. The slider 1052 is threadedly connected to the push rod 1051, that is: an external thread is set on the outer peripheral surface of the push rod 1051, a hole is opened on the slider 1052, and an internal thread is set on the inner surface of the hole, and the two are connected by threads. Further, the push rod 1051 can be a screw, and the slider 1052 can be a nut, and the slider 1052 is limited to move only along the length direction of the push rod 1051, such as by limiting, guiding, etc., the inner catheter 102 is connected to the slider 1052, and further, the proximal end of the inner catheter 102 can extend from the proximal end of the outer catheter 100 to the handle 103 and be connected to the slider 1052, or the push rod 1051 extends into the intermediate catheter 101 and is connected to the proximal end of the inner catheter 102. In this way, the power component 1050 drives the push rod 1051 to reciprocate (forward or reverse), driving the slider 1052 to move forward and backward on the push rod 1051, pushing the inner conduit 102 forward or backward in the intermediate conduit 101. Of course, the control button of the mobile driving mechanism can also be set on the handle 103 for easy operation.

[0063] The balloon 11 is a long expandable balloon, which is used to receive a conductive medium, which includes physiological saline, an X-ray contrast agent, or a mixed solution, etc., and is specifically introduced through a medium channel 104 between the outer catheter 100 and the middle catheter 101. The balloon 11 can be made of non-compliant material, semi-compliant material, or compliant material.

[0064] like Figure 4 As shown: only one pair of electrode pairs 12 is provided, and the electrode pairs 12 are provided on the inner catheter 102. When the inner catheter 102 is moved, the electrode pairs 12 can be exposed from the hole 1010 of the intermediate catheter 101. In this way, when the balloon 11 is filled with a conductive medium, a conductive breakdown is formed between the electrode pairs 12 exposed from the hole 1010 to generate an arc, and the arc generates cavitation bubbles in the conductive medium, thereby generating a mechanical shock wave. In this embodiment: the outer surface of the electrode pair 12 does not protrude from the outer surface of the inner catheter 102, so that the gap between the intermediate catheter 101 and the inner catheter 102 can be reduced, and the conductive medium can be avoided from flowing from the hole 1010 to between the intermediate catheter 101 and the inner catheter 102 as much as possible. For example, a groove can be provided on the outer surface of the inner catheter 102, and the electrode pair 12 is embedded in the groove. The material of the electrode pair 12 is metal, which can be selected from stainless steel, tungsten alloy, platinum-iridium alloy, platinum, gold, etc.

[0065] The electrode pair 12 includes a first electrode 120 and a second electrode 121. One of the first electrode 120 and the second electrode 121 is used to connect to the positive electrode of the power supply, and the other is used to connect to the negative electrode of the power supply. The wire can be connected to the first electrode 120 and the second electrode 121 through the wire cavity of the inner catheter 102. The energy generator 2 is connected to the connector 1032 of the handle 103 through the connecting cable 20, thereby connecting to the first electrode 120 and the second electrode 121 to provide a discharge voltage / current for the first electrode 120 and the second electrode 121. In this embodiment: the first electrode 120 and the second electrode 121 are annularly sleeved on the outer periphery of the inner catheter 102. The annular first electrode 120 and the second electrode 121 can be exposed from the hole 1010 at different angles without rotating the inner catheter 102. The structure is simple and it is also convenient to align with the hole 1010 and then expose, meeting the discharge treatment at different angles.

[0066] In one implementation of this embodiment: the first electrode 120 and the second electrode 121 are exposed from one hole 1010 at the same time.

[0067] In another preferred implementation manner of the present embodiment: the hole 1010 includes a first hole 1010a and a second hole 1010b, the first hole 1010a is used to expose the first electrode 120, and the second hole 1010b is used to expose the second electrode 121, so that the discharge between the first electrode 120 and the second electrode 121 is more controllable, that is, when the first electrode 120 is exposed from the second hole 1010b, or the second electrode 121 is exposed from the first hole 1010a, no shock wave can be generated, and a shock wave can only be generated when the first electrode 120 is exposed from the first hole 1010a and the second electrode 121 is exposed from the second hole 1010b. How to judge whether the first electrode 120 and the second electrode 121 are accurately exposed will be further explained below.

[0068] The energy generator 2 has a detection mode and a discharge mode. In the detection mode, the energy generator 2 determines whether the electrode pair 12 is exposed from the hole 1010. In the discharge mode, the energy generator 2 provides a discharge voltage / current to the electrode pair 12. By determining the position of the electrode pair 12, if the electrode pair 12 is not accurately exposed from the hole 1010, the energy generator 2 cannot switch to the discharge mode to avoid affecting the accuracy of the discharge. In this embodiment, determining whether the electrode pair 12 is accurately exposed from the hole 1010 is to determine whether the first electrode 120 is exposed from the first hole 1010a, and whether the second electrode 121 is exposed from the second hole 1010b.

[0069] Further explanation of the detection mode: when the balloon 11 is filled with a conductive medium, when the electrode pair 12 moves to the position of the hole 1010 corresponding to the middle catheter 101, the electrode pair 12 will be fully exposed to the conductive medium, and an obvious impedance change can be detected. Therefore, when the inner catheter 102 moves, the energy generator 2 detects the impedance of the electrode pair 12 in real time. Specifically, the energy generator 2 sends out an AC signal with a set frequency, such as 1kHz~100kHz. When the impedance of the electrode pair 12 is less than the set impedance value, such as less than 1kΩ, it indicates that the electrode pair 12 is exposed from the hole 1010, and the discharge mode can be entered; when the impedance of the electrode pair 12 increases, or is not less than the set impedance value, it indicates that the electrode pair 12 is not accurately exposed from the hole 1010, and the discharge mode will not be entered.

[0070] Further explanation of the discharge mode: In the discharge mode, when the discharge current reaches the set current value, the energy generator 2 stops providing the discharge current to the electrode pair 12. The set current value is 100A~200A, so as to better control the output of shock wave energy.

[0071] In one implementation of this embodiment: Figure 6 As shown: the energy generator 2 is provided with a detection circuit, which is used to detect the impedance of the electrode pair 12 and / or to detect the discharge current. The detection circuit includes a sampling module 210, a primary amplifier 211, a secondary amplifier, and a digital-to-analog conversion module 213 (ADC). The sampling module 210, the primary amplifier 211, the secondary amplifier 212, and the digital-to-analog conversion module 213 are connected in series in sequence. Among them:

[0072] The sampling module 210 may be a sampling resistor, the resistance of which may be 0.1R-10R. The sampling module 210 may also be a Hall current sensor, which converts a current signal into a voltage signal.

[0073] The first-stage amplifier 211 is used to amplify the voltage signal. The first-stage amplifier 211 usually has a gain of 1 to enhance the driving capability.

[0074] The secondary amplifier includes a first secondary amplifier 2120 and a second secondary amplifier 2121. The first secondary amplifier 2120 and the second secondary amplifier 2121 are connected in parallel. The first secondary amplifier 2120 is used to amplify the impedance signal in the detection mode, and the second secondary amplifier 2121 is used to attenuate the current signal in the discharge mode. The amplification factor of the first secondary amplifier 2120 is 10 to 20 times, and 10 times is taken as an example in this embodiment. The amplification factor of the second secondary amplifier 2121 is 1 / 10 to 1 / 20 times, which is equivalent to an attenuation factor of 10 to 20 times, and 1 / 10 times is taken as an example in this embodiment.

[0075] The digital-to-analog conversion module 213 converts the collected analog signal into a digital signal for output judgment.

[0076] In one implementation of this embodiment: Figure 7 As shown: the energy generator 2 is also provided with an electrode selection circuit, which is used to control the alternating output of positive and negative pulses of the first electrode 120 and the second electrode 121 to achieve bipolar discharge and improve the life of the electrode. The electrode selection circuit includes a first switch device 220, a second switch device 221, a third switch device 222, and a fourth switch device 223. The first switch device 220 and the second switch device 221 are connected in series to form a first path, and the third switch device 222 and the fourth switch device 223 are connected in series to form a second path. The first path and the second path are connected in parallel to the power supply, and the first electrode 120 is connected between the first switch device 220 and the second switch device 221, and the second electrode 121 is connected between the third switch device 222 and the fourth switch device 223. In this embodiment: the first switch device 220, the second switch device 221, the third switch device 222, and the fourth switch device 223 are selected from any one of IGBT and MOSFET. The electrode selection circuit can change the polarity of the first electrode 120 and the second electrode 121, reduce the loss of the electrode pair 12 caused by discharge, and ensure the discharge accuracy.

[0077] In one implementation of this embodiment: Figure 8 As shown: the detection circuit and the electrode selection circuit are integrated together, specifically: the first switch device 220, the second switch device 221, the third switch device 222, and the fourth switch device 223 are all transistors, the emitter of the first switch device 220 is connected to the collector of the second switch device 221 to form a first path, the emitter of the third switch device 222 is connected to the collector of the fourth switch device 223 to form a second path, after the first path and the second path are connected in parallel, the collectors of the first switch device 220 and the third switch device 222 are switched between the power supply (HV) or the signal source through the switch device or the relay K1, the emitters of the second switch device 221 and the fourth switch device 223 are connected to the sampling module 210 of the detection circuit, and the bases of the first switch device 220, the second switch device 221, the third switch device 222, and the fourth switch device 223 are connected to the driver.

[0078] When working, first enter the detection mode: switch K1 is switched to the signal source, the signal source generates an AC signal with a frequency of 50kHz, the second switch device 221 and the third switch device 222 are turned on, and the current passes through the third switch device 222, the second electrode 121, the first electrode 120, and the second switch device 221. The impedance at both ends of the first electrode 120 and the second electrode 121 is collected in real time through the detection circuit. When the impedance between the first electrode 120 and the second electrode 121 is less than 1kΩ, it means that the first electrode 120 and the second electrode 121 are accurately exposed from the first hole 1010a and the second hole 1010b, and the discharge mode can be entered; when the impedance between the first electrode 120 and the second electrode 121 increases, such as 2kΩ, it means that the first electrode 120 and the second electrode 121 are not accurately exposed from the first hole 1010a and the second hole 1010b. At this time, it is necessary to move the inner catheter 102 to adjust the position of the first electrode 120 and the second electrode 121.

[0079] When entering the discharge mode, the switch K1 switches to the HV high-voltage power supply, and the first electrode 120 and the second electrode 121 can output bipolar high-voltage ns-level pulses through the first switch device 220, the second switch device 221, the third switch device 222, and the fourth switch device 223. When the second switch device 221 and the third switch device 222 are turned on, the first electrode 120 and the second electrode 121 output positive pulses. When the first switch device 220 and the fourth switch device 223 are turned on, the first electrode 120 and the second electrode 121 output negative pulses.

[0080] After the electrode pair 12 discharges at a hole 1010 for a preset number of groups, the moving drive mechanism controls the inner catheter 102 to move to the position of the next hole 1010 in the intermediate catheter 101 to continue the treatment at the next position. The operator can set parameters such as the length of the treatment lesion and the number of treatments at a single hole 1010.

[0081] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with the technology to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the protection scope of the present invention.

Claims

1. A shock wave guide system, characterized in that: include: Catheter assembly: The catheter assembly comprises an outer catheter, an intermediate catheter and an inner catheter. The intermediate catheter is inserted into the outer catheter, and the distal end of the intermediate catheter extends out of the distal end of the outer catheter. The intermediate catheter is provided with a plurality of holes, and the plurality of holes are distributed along the length direction of the intermediate catheter. The inner catheter is inserted into the intermediate catheter, and the inner catheter can move in the length direction of the intermediate catheter. Balloon: the proximal end of the balloon is connected to the distal end of the outer catheter, and the distal end of the balloon is connected to the distal end of the intermediate catheter; Electrode pair: The electrode pair is provided in one pair only, and the electrode pair is provided on the inner conduit. By moving the inner conduit, the electrode pair can be exposed from the hole of the intermediate conduit.

2. The shock wave guide system according to claim 1, characterized in that: A medium channel is formed between the outer catheter and the middle catheter, and the conductive medium is injected into the balloon through the medium channel; When the balloon is filled with a conductive medium, the electrodes exposed from the holes are electrically conductively broken down to form a shock wave.

3. The shock wave guide system according to claim 1, characterized in that: The electrode pair includes a first electrode and a second electrode, one of which is used to connect to the positive electrode of a power source, and the other is used to connect to the negative electrode of the power source. The first electrode and the second electrode are annularly sleeved on the outer periphery of the inner catheter.

4. The shock wave guide system according to claim 3, characterized in that: The holes include a first hole and a second hole. The first hole is used to expose the first electrode, and the second hole is used to expose the second electrode.

5. The shock wave guide system according to claim 1 or 3, characterized in that: The outer surface of the electrode pair does not protrude from the outer surface of the inner catheter.

6. The shock wave guide system according to claim 1, characterized in that: Two adjacent holes are staggered in the circumferential direction of the intermediate conduit, and the staggered angle is 30°-180°.

7. The shock wave guide system according to claim 1, characterized in that: The hole is located on the middle catheter inside the balloon.

8. The shock wave guide system according to claim 1, characterized in that: The gap between the intermediate conduit and the inner conduit does not exceed 0.2 mm.

9. The shock wave guide system according to claim 1, characterized in that: The catheter assembly also includes a handle, which is connected to the proximal end of the outer catheter. A mobile driving mechanism is arranged in the handle, and the mobile driving mechanism is connected to the inner catheter for driving the inner catheter to move.

10. The shock wave guide system according to claim 9, characterized in that: The mobile driving mechanism includes a power component, a push rod, and a slider. The power component is connected to the push rod in a transmission manner and is used to drive the push rod to rotate around its own axis. The slider is threadedly connected to the push rod, and the slider is restricted to move only along the push rod. The inner catheter is connected to the slider.

11. The shock wave guide system according to claim 1, characterized in that: The system also includes an energy generator, which is connected to the electrode pair.

12. The shock wave guide system according to claim 11, characterized in that: The energy generator has a detection mode and a discharge mode. In the detection mode: the energy generator determines whether the electrode pair is exposed from the hole; in the discharge mode: the energy generator provides a discharge voltage / current to the electrode pair.

13. The shock wave guide system according to claim 12, characterized in that: When the energy generator determines whether the electrode pair is exposed from the hole, it includes sending an AC signal of a set frequency to detect the impedance of the electrode pair. When the impedance of the electrode pair is less than the set impedance value, it is determined that the electrode pair is exposed from the hole.

14. The shock wave guide system according to claim 12 or 13, characterized in that: The energy generator is provided with a detection circuit, which is used to detect the impedance of the electrode pair and / or to detect the discharge current. The detection circuit includes a sampling module, a primary amplifier, a secondary amplifier, and a digital-to-analog conversion module. The sampling module, the primary amplifier, the secondary amplifier, and the digital-to-analog conversion module are connected in series in sequence.

15. The shock wave guide system according to claim 14, characterized in that: The secondary amplifier includes a first secondary amplifier and a second secondary amplifier, the first secondary amplifier and the second secondary amplifier are connected in parallel, the first secondary amplifier is used to amplify the impedance signal in the detection mode, and the second secondary amplifier is used to attenuate the current signal in the discharge mode.

16. The shock wave guide system of claim 12, wherein: In the discharge mode, when the discharge current reaches a set current value, the energy generator stops providing the discharge current to the electrode pair.

17. The shock wave guide system of claim 11, wherein: The energy generator is provided with an electrode selection circuit, which includes a first switching device, a second switching device, a third switching device, and a fourth switching device. The first switching device and the second switching device are connected in series to form a first path, the third switching device and the fourth switching device are connected in series to form a second path, the first path and the second path are connected in parallel to a power supply, the first electrode of the electrode pair is connected between the first switching device and the second switching device, and the second electrode of the electrode pair is connected between the third switching device and the fourth switching device.

18. The shock wave guide system according to claim 17, characterized in that: The first path and the second path are connected in parallel and switched between the power source or the signal source through a switch device or a relay.

19. The shock wave guide system of claim 17, wherein: The first switch device, the second switch device, the third switch device and the fourth switch device are selected from any one of IGBT and MOSFET.

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