A processing technology for drinking water rich in active hydrogen

Abstract

The present invention discloses a processing technology for active hydrogen-rich drinking water, belonging to the technical field of drinking water. It comprises a long cylindrical vertically placed tube body for processing the active hydrogen-rich drinking water, the top of the tube body is provided with a water inlet, the bottom of the tube body is provided with a water outlet, and porous ceramic sheets and filter membrane layers are sequentially arranged along the direction from the water inlet to the water outlet; the processing technology for preparing active hydrogen-rich drinking water using the tube body comprises the following steps: introducing drinking water from the water inlet, passing through the porous ceramic sheets and filter membrane layers in sequence, flowing out through the water outlet, encapsulating, sterilizing, and obtaining the active hydrogen-rich drinking water; so that the prepared drinking water is rich in active hydrogen, and the refreshing, anti-oxidation and anti-fatigue effects are improved.

Description

Technical Field

[0001] The invention belongs to the technical field of drinking water, and in particular relates to a processing technology for drinking water rich in active hydrogen. Background Art

[0002] The concept of active hydrogen-rich drinking water involves a special drinking water characterized by the incorporation of active hydrogen molecules into the water. Active hydrogen is a highly reducing form of hydrogen gas that exists in water as hydrogen ions, a state in which hydrogen has more active chemical properties than ordinary water molecules. This water is believed to provide a range of health benefits, including but not limited to helping with antioxidants, promoting cell health, and possibly having a positive effect on improving certain physiological functions. Specifically, due to their tiny molecular weight and high reducing properties, active hydrogen molecules are able to neutralize free radicals in the body, a type of molecule that is often associated with oxidative stress. Free radicals can cause damage to cells and may lead to a variety of health problems. By neutralizing these free radicals, active hydrogen drinking water may help slow down the oxidation process, thereby helping to protect the body from oxidative damage, which is often associated with aging and the development of related diseases. In addition, studies have pointed out that active hydrogen water may have potential positive effects on improving blood circulation, reducing the level of harmful cholesterol in the blood, enhancing the function of the immune system, and promoting metabolism. The existing active hydrogen drinking water has a problem in the preparation process, which causes the active hydrogen molecules to escape or react with other substances due to the instability of the active hydrogen molecules during the preparation process, thereby reducing their content in the drinking water. Summary of the invention

[0003] The purpose of the present invention is to provide a processing technology for drinking water rich in active hydrogen, which is used to increase the active hydrogen content in drinking water.

[0004] The purpose of the present invention can be achieved through the following technical solutions:

[0005] A processing technology for active hydrogen-rich drinking water, comprising a long cylindrical vertically placed tube body for processing the active hydrogen-rich drinking water, a water inlet being opened at the top of the tube body, a water outlet being opened at the bottom of the tube body, and porous ceramic sheet layers and filter membrane layers being sequentially arranged along the direction from the water inlet to the water outlet;

[0006] The process for preparing drinking water rich in active hydrogen by using the tube body comprises the following steps:

[0007] Drinking water is introduced from the water inlet, flows through the porous ceramic sheet layer and the filter membrane layer in sequence, flows out through the water outlet, is packaged and sterilized, and thus the active hydrogen-rich drinking water is obtained.

[0008] As a preferred technical solution of the present invention, the method for preparing the filter membrane layer comprises the following steps:

[0009] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 20-30 min, stir at 50°C for 5-6 h, cool in an ice-water bath, filter, wash and dry the solid phase to obtain material A;

[0010] S2, take the material A and dimethyl sulfoxide, mix, stir for 20-30 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 2-3 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 2-3 hours, wash with water, filter, take the solid phase and dry it to obtain material B;

[0011] S3, taking 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol, mixing, refluxing and stirring at 70-75°C for 20-30h, cooling in an ice water bath, filtering, washing and vacuum drying the solid phase to obtain material C;

[0012] S4. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6-8h, then heat to 160°C and continue stirring for 8-10h, immerse in deionized water, crush, and vacuum dry to obtain material D;

[0013] S5, zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, and polycaprolactone were mixed, stirred at 60° C. for 1-2 hours, the material D was added, ultrasonically stirred for 3-4 hours, N-methylpyrrolidone was added, and stirred for 3-4 hours to obtain material E; the concentration of the ammonia water was 5 mol / L;

[0014] S6. Mix the material B and N-methylpyrrolidone, stir for 3-4 hours, add the material E, stir for 2-3 hours, filter, let the liquid stand for degassing, then pour and spread on a glass plate, dry at 75-85°C and vacuum degree -50kPa for 20-30 hours to obtain the filter membrane layer.

[0015] As a preferred technical solution of the present invention, in step S1, the dosage ratio of the polyetheretherketone and concentrated sulfuric acid is 18-22 g: 350-400 mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%.

[0016] As a preferred technical solution of the present invention, in step S2, the dosage ratio of material A, dimethyl sulfoxide, N,N'-carbonyldiimidazole and N-(3-aminopropyl)imidazole is 7-8g:80-90mL:1-1.5g:0.7-0.75g.

[0017] As a preferred technical solution of the present invention, in step S3, the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol is 70-80 g: 250 mL: 1 L.

[0018] As a preferred technical solution of the present invention, in step S4, the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9-10g: 7-8g: 4-5g: 45-50g: 10-12mL: 500mL.

[0019] As a preferred technical solution of the present invention, in step S5, the dosage ratio of the zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.6-0.8 g: 50 mL: 50 mL: 20 mL: 0.1-0.15 g: 1.2-1.4 g: 5-6 mL.

[0020] As a preferred technical solution of the present invention, in step S6, the dosage ratio of material B, N-methylpyrrolidone and material E is 1.2-1.4 g: 5-6 mL: 1.2-1.4 g.

[0021] As a preferred technical solution of the present invention, the porous ceramic sheet is a porous ceramic sheet made of magnesium tourmaline.

[0022] As a preferred technical solution of the present invention, the dosage ratio of the drinking water, the porous ceramic sheet layer, and the filter membrane layer is 500L: 8-10g: 4-6g.

[0023] Beneficial effects of the present invention:

[0024] (1) The present invention discloses a process for producing drinking water rich in active hydrogen. In the process of preparing the filter membrane layer, a specific chemical reaction and material selection are performed to make the filter membrane layer have excellent active hydrogen adsorption and transport capabilities. At the same time, the ratio of drinking water to the porous ceramic sheet layer and the filter membrane layer is also precisely controlled to ensure the uniform distribution and stable existence of active hydrogen molecules in the drinking water, so that the prepared drinking water is rich in active hydrogen, thereby improving the refreshing, anti-oxidation and anti-fatigue effects. DETAILED DESCRIPTION

[0025] In order to further illustrate the technical means and effects adopted by the present invention to achieve the predetermined invention purpose, the specific implementation methods, structures, features and effects of the present invention are described in detail below in combination with the embodiments.

[0026] Example 1

[0027] A processing technology for active hydrogen-rich drinking water, comprising a long cylindrical vertically placed tube body for processing the active hydrogen-rich drinking water, a water inlet being provided at the top of the tube body, a water outlet being provided at the bottom of the tube body, and a porous ceramic sheet layer and a filter membrane layer made of magnesium tourmaline being sequentially provided along the direction from the water inlet to the water outlet;

[0028] The process for preparing drinking water rich in active hydrogen by using the tube body comprises the following steps:

[0029] Drinking water is introduced from the water inlet, flows through the porous ceramic sheet layer and the filter membrane layer in sequence, flows out through the water outlet, is packaged and sterilized, and thus the active hydrogen-rich drinking water is obtained; the dosage ratio of the drinking water, the porous ceramic sheet layer, and the filter membrane layer is 500L:8g:4g;

[0030] The preparation method of the filter membrane layer comprises the following steps:

[0031] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 20 minutes, stir at 50°C for 5 hours, cool in an ice-water bath, filter, wash the solid phase, and dry to obtain material A; the dosage ratio of polyetheretherketone and concentrated sulfuric acid is 18g:350mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%;

[0032] S2, take the material A and dimethyl sulfoxide, mix, stir for 20 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 2 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 2 hours, wash with water, filter, take the solid phase and dry to obtain material B; the amount ratio of material A, dimethyl sulfoxide, N, N'-carbonyldiimidazole, and N-(3-aminopropyl) imidazole is 7g:80mL:1g:0.7g;

[0033] S3, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol were mixed, refluxed and stirred at 70°C for 20h, cooled in an ice-water bath, filtered, the solid phase was washed and vacuum dried to obtain material C; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol was 70g:250mL:1L;

[0034] S4. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6 hours, then heat to 160°C and continue stirring for 8 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9g:7g:4g:45g:10mL:500mL;

[0035] S5. Mix zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, and polycaprolactone, stir at 60°C for 1 hour, add the material D, ultrasonically stir for 3 hours, add N-methylpyrrolidone, and stir for 3 hours to obtain material E; the concentration of the ammonia water is 5 mol / L; the dosage ratio of the zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.6g:50mL:50mL:20mL:0.1g:1.2g:5mL;

[0036] S6. Take the material B and N-methylpyrrolidone, mix them, stir for 3 hours, add the material E, stir for 2 hours, filter, take the liquid phase and let it stand for degassing, then pour it and spread it on a glass plate, dry it at 75°C and vacuum degree of -50 kPa for 20 hours to obtain the filter membrane layer; the dosage ratio of the material B, N-methylpyrrolidone and material E is 1.2g:5mL:1.2g.

[0037] Example 2

[0038] A processing technology for active hydrogen-rich drinking water, comprising a long cylindrical vertically placed tube body for processing the active hydrogen-rich drinking water, a water inlet being provided at the top of the tube body, a water outlet being provided at the bottom of the tube body, and a porous ceramic sheet layer and a filter membrane layer made of magnesium tourmaline being sequentially provided along the direction from the water inlet to the water outlet;

[0039] The process for preparing drinking water rich in active hydrogen by using the tube body comprises the following steps:

[0040] Drinking water is introduced from the water inlet, flows through the porous ceramic sheet layer and the filter membrane layer in sequence, flows out through the water outlet, is packaged and sterilized, and thus the active hydrogen-rich drinking water is obtained; the dosage ratio of the drinking water, the porous ceramic sheet layer, and the filter membrane layer is 500L:9g:5g;

[0041] The preparation method of the filter membrane layer comprises the following steps:

[0042] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 25 minutes, stir at 50°C for 5.5 hours, cool in an ice-water bath, filter, wash the solid phase, and dry to obtain material A; the dosage ratio of polyetheretherketone and concentrated sulfuric acid is 20g:380mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%;

[0043] S2, take the material A and dimethyl sulfoxide, mix, stir for 25 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 2.5 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 2.5 hours, wash with water, filter, take the solid phase and dry to obtain material B; the amount ratio of material A, dimethyl sulfoxide, N, N'-carbonyldiimidazole, and N-(3-aminopropyl) imidazole is 7.5g:85mL:1.2g:0.72g;

[0044] S3, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol were mixed, refluxed and stirred at 72°C for 25h, cooled in an ice-water bath, filtered, the solid phase was washed and vacuum dried to obtain material C; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol was 75g:250mL:1L;

[0045] S4. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 7 hours, then heat to 160°C and continue stirring for 9 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9.5g:7.5g:4.5g:48g:11mL:500mL;

[0046] S5. Mix zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, and polycaprolactone, stir at 60°C for 1.5h, add the material D, ultrasonically stir for 3.5h, add N-methylpyrrolidone, and stir for 3.5h to obtain material E; the concentration of the ammonia water is 5 mol / L; the dosage ratio of the zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.7g:50mL:50mL:20mL:0.13g:1.3g:5.5mL;

[0047] S6. Mix the material B and N-methylpyrrolidone, stir for 3.5 hours, add the material E, stir for 2.5 hours, filter, let the liquid stand for degassing, then pour and spread on a glass plate, dry at 80°C and vacuum degree -50 kPa for 25 hours to obtain the filter membrane layer; the dosage ratio of the material B, N-methylpyrrolidone and material E is 1.3g:5.5mL:1.3g.

[0048] Example 3

[0049] A processing technology for active hydrogen-rich drinking water, comprising a long cylindrical vertically placed tube body for processing the active hydrogen-rich drinking water, a water inlet being provided at the top of the tube body, a water outlet being provided at the bottom of the tube body, and a porous ceramic sheet layer and a filter membrane layer made of magnesium tourmaline being sequentially provided along the direction from the water inlet to the water outlet;

[0050] The process for preparing drinking water rich in active hydrogen by using the tube body comprises the following steps:

[0051] Drinking water is introduced from the water inlet, flows through the porous ceramic sheet layer and the filter membrane layer in sequence, flows out through the water outlet, is packaged and sterilized, and thus the active hydrogen-rich drinking water is obtained; the dosage ratio of the drinking water, the porous ceramic sheet layer, and the filter membrane layer is 500L:10g:6g;

[0052] The preparation method of the filter membrane layer comprises the following steps:

[0053] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 30 minutes, stir at 50°C for 6 hours, cool in an ice-water bath, filter, wash the solid phase, and dry to obtain material A; the dosage ratio of polyetheretherketone and concentrated sulfuric acid is 22g:400mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%;

[0054] S2, take the material A and dimethyl sulfoxide, mix, stir for 30 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 3 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 3 hours, wash with water, filter, take the solid phase and dry to obtain material B; the amount ratio of material A, dimethyl sulfoxide, N, N'-carbonyldiimidazole, and N-(3-aminopropyl) imidazole is 8g:90mL:1.5g:0.75g;

[0055] S3, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol were mixed, refluxed and stirred at 75°C for 30h, cooled in an ice-water bath, filtered, the solid phase was washed and vacuum dried to obtain material C; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol was 80g:250mL:1L;

[0056] S4. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 8 hours, then heat to 160°C and continue stirring for 10 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 10g:8g:5g:50g:12mL:500mL;

[0057] S5. Mix zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, and polycaprolactone, stir at 60°C for 2h, add material D, ultrasonically stir for 4h, add N-methylpyrrolidone, and stir for 4h to obtain material E; the concentration of ammonia water is 5 mol / L; the dosage ratio of zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.8g:50mL:50mL:20mL:0.15g:1.4g:6mL;

[0058] S6. Mix the material B and N-methylpyrrolidone, stir for 4 hours, add the material E, stir for 3 hours, filter, let the liquid stand for degassing, then pour and spread on a glass plate, dry at 85°C and vacuum degree -50 kPa for 30 hours to obtain the filter membrane layer; the dosage ratio of the material B, N-methylpyrrolidone and material E is 1.4g:6mL:1.4g.

[0059] Comparative Example 1

[0060] The difference from Example 1 is that the method for preparing the filter membrane layer comprises the following steps:

[0061] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 20 minutes, stir at 50°C for 5 hours, cool in an ice-water bath, filter, wash the solid phase, and dry to obtain material A; the dosage ratio of polyetheretherketone and concentrated sulfuric acid is 18g:350mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%;

[0062] S2, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol were mixed, refluxed and stirred at 70°C for 20h, cooled in an ice-water bath, filtered, the solid phase was washed and vacuum dried to obtain material C; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol was 70g:250mL:1L;

[0063] S3. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6 hours, then heat to 160°C and continue stirring for 8 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9g:7g:4g:45g:10mL:500mL;

[0064] S4, take zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, mix, stir at 60 ° C for 1 hour, add the material D, ultrasonically stir for 3 hours, add N-methylpyrrolidone, stir for 3 hours, and obtain material E; the concentration of the ammonia water is 5 mol / L; the dosage ratio of the zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.6g:50mL:50mL:20mL:0.1g:1.2g:5mL;

[0065] S5. Mix the material A and N-methylpyrrolidone, stir for 3 h, add the material E, stir for 2 h, filter, let the liquid stand for degassing, then pour and spread on a glass plate, dry at 75 ° C and vacuum degree -50 kPa for 20 h to obtain the filter membrane layer; the dosage ratio of the material A, N-methylpyrrolidone and material E is 1.2 g: 5 mL: 1.2 g.

[0066] Comparative Example 2

[0067] The difference from Example 1 is that the method for preparing the filter membrane layer comprises the following steps:

[0068] S1. Mix 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol, reflux and stir at 70°C for 20h, cool in an ice-water bath, filter, wash and vacuum dry the solid phase to obtain material C; the ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol is 70g:250mL:1L;

[0069] S2. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6 hours, then heat to 160°C and continue stirring for 8 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9g:7g:4g:45g:10mL:500mL;

[0070] S3, zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone were mixed, stirred at 60°C for 1h, material D was added, ultrasonic stirring was performed for 3h, N-methylpyrrolidone was added, and the mixture was stirred for 3h to obtain material E; the concentration of ammonia water was 5 mol / L; the dosage ratio of zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone was 0.6g:50mL:50mL:20mL:0.1g:1.2g:5mL;

[0071] S4. Mix the N-methylpyrrolidone and material E, stir for 2 hours, filter, let the liquid stand for degassing, then pour and spread on a glass plate, and dry at 75°C and vacuum degree of -50 kPa for 20 hours to obtain the filter membrane layer; the dosage ratio of N-methylpyrrolidone and material E is 5 mL:1.2 g.

[0072] Comparative Example 3

[0073] The difference from Example 1 is that the method for preparing the filter membrane layer comprises the following steps:

[0074] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 20 minutes, stir at 50°C for 5 hours, cool in an ice-water bath, filter, wash the solid phase, and dry to obtain material A; the dosage ratio of polyetheretherketone and concentrated sulfuric acid is 18g:350mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%;

[0075] S2, take the material A and dimethyl sulfoxide, mix, stir for 20 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 2 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 2 hours, wash with water, filter, take the solid phase and dry to obtain material B; the amount ratio of material A, dimethyl sulfoxide, N, N'-carbonyldiimidazole, and N-(3-aminopropyl) imidazole is 7g:80mL:1g:0.7g;

[0076] S3, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol were mixed, refluxed and stirred at 70°C for 20h, cooled in an ice-water bath, filtered, the solid phase was washed and vacuum dried to obtain material C; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol was 70g:250mL:1L;

[0077] S4. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6 hours, then heat to 160°C and continue stirring for 8 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9g:7g:4g:45g:10mL:500mL;

[0078] S5. Mix anhydrous ethanol, deionized water, ammonia water and polycaprolactone, stir at 60°C for 1h, add the material D, stir ultrasonically for 3h, add N-methylpyrrolidone, stir for 3h, and obtain material E; the concentration of the ammonia water is 5 mol / L; the dosage ratio of the anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D and N-methylpyrrolidone is 50mL:50mL:20mL:0.1g:1.2g:5mL;

[0079] S6. Take the material B and N-methylpyrrolidone, mix them, stir for 3 hours, add the material E, stir for 2 hours, filter, take the liquid phase and let it stand for degassing, then pour it and spread it on a glass plate, dry it at 75°C and vacuum degree of -50 kPa for 20 hours to obtain the filter membrane layer; the dosage ratio of the material B, N-methylpyrrolidone and material E is 1.2g:5mL:1.2g.

[0080] Comparative Example 4

[0081] The difference from Example 1 is that the method for preparing the filter membrane layer comprises the following steps:

[0082] S1. Mix polyetheretherketone and dimethyl sulfoxide, stir for 20 minutes, add N,N'-carbonyldiimidazole, stir at 60°C for 2 hours, add N-(3-aminopropyl)imidazole, stir at 60°C for 2 hours, wash with water, filter, and dry the solid phase to obtain material B; the dosage ratio of polyetheretherketone, dimethyl sulfoxide, N,N'-carbonyldiimidazole, and N-(3-aminopropyl)imidazole is 7g:80mL:1g:0.7g;

[0083] S2, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol were mixed, refluxed and stirred at 70°C for 20h, cooled in an ice-water bath, filtered, the solid phase was washed and vacuum dried to obtain material C; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol was 70g:250mL:1L;

[0084] S3. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6 hours, then heat to 160°C and continue stirring for 8 hours, immerse in deionized water, crush, and vacuum dry to obtain material D; the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9g:7g:4g:45g:10mL:500mL;

[0085] S4, take zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, mix, stir at 60 ° C for 1 hour, add the material D, ultrasonically stir for 3 hours, add N-methylpyrrolidone, stir for 3 hours, and obtain material E; the concentration of the ammonia water is 5 mol / L; the dosage ratio of the zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.6g:50mL:50mL:20mL:0.1g:1.2g:5mL;

[0086] S5. Mix the material B and N-methylpyrrolidone, stir for 3 hours, add the material E, stir for 2 hours, filter, let the liquid stand for degassing, then pour and spread on a glass plate, dry at 75°C and vacuum degree of -50 kPa for 20 hours to obtain the filter membrane layer; the dosage ratio of the material B, N-methylpyrrolidone and material E is 1.2g:5mL:1.2g.

[0087] Comparative Example 5

[0088] The difference from Example 1 is that the method for preparing the filter membrane layer comprises the following steps:

[0089] S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 20 minutes, stir at 50°C for 5 hours, cool in an ice-water bath, filter, wash the solid phase, and dry to obtain material A; the dosage ratio of polyetheretherketone and concentrated sulfuric acid is 18g:350mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%;

[0090] S2, take the material A and dimethyl sulfoxide, mix, stir for 20 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 2 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 2 hours, wash with water, filter, take the solid phase and dry to obtain material B; the amount ratio of material A, dimethyl sulfoxide, N, N'-carbonyldiimidazole, and N-(3-aminopropyl) imidazole is 7g:80mL:1g:0.7g;

[0091] S3. In a nitrogen atmosphere, 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide and toluene were mixed, refluxed at 150°C with stirring for 6 hours, then heated to 160°C and stirred for 8 hours, immersed in deionized water, crushed and vacuum dried to obtain material D; the dosage ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene and deionized water was 9g:7g:4g:45g:10mL:500mL;

[0092] S5. Mix zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, and polycaprolactone, stir at 60°C for 1 hour, add the material D, ultrasonically stir for 3 hours, add N-methylpyrrolidone, and stir for 3 hours to obtain material E; the concentration of the ammonia water is 5 mol / L; the dosage ratio of the zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.6g:50mL:50mL:20mL:0.1g:1.2g:5mL;

[0093] S6. Take the material B and N-methylpyrrolidone, mix them, stir for 3 hours, add the material E, stir for 2 hours, filter, take the liquid phase and let it stand for degassing, then pour it and spread it on a glass plate, dry it at 75°C and vacuum degree of -50 kPa for 20 hours to obtain the filter membrane layer; the dosage ratio of the material B, N-methylpyrrolidone and material E is 1.2g:5mL:1.2g.

[0094] Performance Testing

[0095] Test Example 1

[0096] Safety tests were conducted on the active hydrogen-rich drinking water prepared in Examples 1-3 and Comparative Examples 1-6, and oral acute toxicity tests were conducted using SD rats (refer to GB / T 15193.3-2003), and the rats were observed for abnormal reactions (such as ruffled hair, lethargy, pale or congested ears, exophthalmos, staggering, muscle paralysis, dyspnea, coma, convulsions, incontinence, etc.), death, and the cause of death was analyzed;

[0097] A 180-day feeding test (short-term oral toxicity test, subacute toxicity test, refer to GB / T 23179-2008) was conducted to observe growth status, body weight and food utilization, hematological and blood biochemical indices, and pathological changes in the heart, liver, spleen, lung, kidney, stomach, intestine, etc. were observed by autopsy. The organ system values ​​of the liver, kidney, spleen, testicle (male) and ovary (female) were measured, and the organ system value (organ / body weight×100%) was calculated.

[0098] Test results: All the tested rats grew and developed well, and their behavior, mental state, coat color, eating, and defecation were normal, revealing that GB / T 15193.3-2003 in the embodiments and comparative examples had no adverse effects on the general condition of rats, on the weight gain and growth and development of rats, on the food utilization rate, on the basic hematological indicators, on the main indicators of blood biochemistry, and on the major organs.

[0099] It is shown that the active hydrogen-rich drinking water of the present application has no acute toxic side effects, and long-term drinking has no adverse effects on weight gain, food utilization, hematology, organs and other indicators, and can be drunk for a long time.

[0100] Test Example 2

[0101] Refreshing and anti-fatigue function test

[0102] Test Example 2-1 Open Field Test

[0103] 1. Test subjects

[0104] The method for obtaining active hydrogen-rich drinking water is shown in Examples 1-3 and Comparative Examples 1-5.

[0105] 2. Experimental animals and experimental methods

[0106] The experimental animals were healthy male Wistar rats.

[0107] The pharmacological test method (Xu Shuyun: Pharmacological Test Method, Second Edition, People's Medical Publishing House, 1994) was used, and the process was as follows: the animals were fasted overnight and randomly divided into a water-fed group and a group fed with drinking water rich in active hydrogen. They were suspended in 37°C water for 6 hours (a new swimming method, see Xiao Jinteng et al.: Research on the application of rat suspension swimming in exercise tests. Chinese Journal of Applied Physiology, 1997, 13 (Supplement): 46). They were fed three times, 100 mL per head each time, at 2, 4, and 6 hours after the start of swimming. The control group was fed with distilled water, and the experimental group was fed with drinking water rich in active hydrogen.

[0108] After swimming, open field behavior was measured in an open field box to reflect the effect of drinking water rich in active hydrogen on brain function.

[0109] 3. Test results

[0110] After the animals had been suspended swimming in 37°C water for 6 hours, open field behavior was measured. From the results of the two indicators of the number of stays in the center grid and the number of grids traveled, it can be seen that the brain function state of the animals in the water-fed group was significantly worse than that of the animals in the group fed with active hydrogen-rich drinking water, indicating that the active hydrogen-rich drinking water had a significant refreshing effect, see Table 1 below.

[0111] Table 1 Effects of drinking water rich in active hydrogen on open field behavior of animals after swimming

[0112]

[0113] Statistical analysis: *P < 0.05, data on the center grid stay were analyzed using t-test, and data on the number of grids traveled were analyzed using rank sum test.

[0114] Test Example 2-2 Swimming Exhaustion Test

[0115] 1. Test subjects

[0116] The method for obtaining drinking water rich in active hydrogen is as shown in Example 2.

[0117] 2. Experimental animals and experimental methods

[0118] The experimental animals were healthy male Wistar rats.

[0119] Test method:

[0120] Before the formal experiment, the animals were trained in swimming at least twice, each time for 30 min;

[0121] In the formal experiment, the animals were suspended and swam in 37°C water after fasting overnight. During the swimming period, they were fed every 2 hours, 100 mL per animal each time. The control group drank distilled water, and the experimental group was fed drinking water rich in active hydrogen.

[0122] When the animal becomes tired of swimming, its head will be submerged in water. If this happens three times, each time for more than 5 seconds, it is considered swimming exhaustion.

[0123] 3. Test results

[0124] Using t-test analysis (**P<0.01), the average exhaustion time of the animals in the group fed with active hydrogen-rich drinking water was 15.3h, which was significantly longer than that of the animals in the group fed with distilled water (12.4h), indicating that the active hydrogen-rich drinking water had a significant anti-fatigue effect.

[0125] Test Example 2-3 Swimming Metabolic Test

[0126] 1. Test subjects

[0127] The method for obtaining active hydrogen-rich drinking water is as shown in Example 3.

[0128] 2. Experimental animals and experimental methods

[0129] The experimental animals were healthy male Wistar rats.

[0130] The swimming metabolism test is used to reflect the effect of active hydrogen-rich drinking water on the exercise metabolism of animals, that is, the biochemical mechanism of the refreshing and anti-fatigue effect of active hydrogen-rich drinking water. Six hours before and after swimming, orbital blood, muscle and liver samples were collected, and blood glucose, lactic acid, triglyceride, blood free fatty acids (free fatty acid), albumin, urea nitrogen (BUN), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSHPx), lactate dehydrogenase (LDH), creatine kinase (CK), aspartate aminotransferase (GOT), alanine aminotransferase (GPT), muscle glycogen and liver glycogen were measured by automatic biochemical analyzer (Cobas Mira 31-0052) and Nanjing Jiancheng Bioengineering Research Institute kits. The control group drank distilled water, and the experimental group was fed with active hydrogen-rich drinking water.

[0131] 3. Test results

[0132] Before swimming, all indicators of the two groups of animals (including heart, liver, and kidney function indicators) were within normal range;

[0133] After swimming, the blood glucose, albumin and triglyceride concentrations of the animals in the distilled water group decreased significantly, and the levels of lactic acid, BUN, MDA, CK, GOT, GPT and LDH increased, indicating that the animals' exercise metabolism accelerated; however, the triglyceride and fatty acid concentrations of the animals in the active hydrogen-rich drinking water group were significantly higher than those of the animals in the distilled water group, while the MDA level was significantly lower than that of the animals in the distilled water group; in addition, the SOD activity of the animals in the active hydrogen-rich drinking water group after swimming was significantly increased compared with that before swimming, indicating that active hydrogen-rich drinking water has the effect of promoting and improving energy metabolism, promoting fat mobilization in the body, and enhancing antioxidant function; active hydrogen-rich drinking water has no significant effect on the levels of muscle glycogen and liver glycogen in swimming animals.

[0134] Table 2 Regulatory effects of the tested active hydrogen-rich drinking water on animal exercise metabolism

[0135]

[0136]

[0137] Statistical analysis: *P<0.05, **P<0.01, compared with the distilled water group and the active hydrogen-rich drinking water group; ×P<0.05, ××P<0.01, compared with before and after swimming; t-test was used for analysis.

[0138] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A processing technology for drinking water rich in active hydrogen, It is characterized in that It comprises a long cylindrical vertically placed tube body for processing the active hydrogen-rich drinking water, the top of the tube body is provided with a water inlet, the bottom of the tube body is provided with a water outlet, and porous ceramic sheets and filter membrane layers are sequentially arranged along the direction from the water inlet to the water outlet; The processing technology for preparing drinking water rich in active hydrogen by using the tube body comprises the following steps: Drinking water is introduced from the water inlet, flows through the porous ceramic sheet layer and the filter membrane layer in sequence, flows out through the water outlet, is packaged and sterilized, and thus the active hydrogen-rich drinking water is obtained; The preparation method of the filter membrane layer comprises the following steps: S1. Mix polyetheretherketone and concentrated sulfuric acid, stir for 20-30 min, stir at 50°C for 5-6 h, cool in an ice-water bath, filter, wash and dry the solid phase to obtain material A; S2, take the material A and dimethyl sulfoxide, mix, stir for 20-30 minutes, add N, N'-carbonyldiimidazole, stir at 60 ° C for 2-3 hours, add N-(3-aminopropyl) imidazole, stir at 60 ° C for 2-3 hours, wash with water, filter, take the solid phase and dry it to obtain material B; S3, taking 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol, mixing, refluxing and stirring at 70-75°C for 20-30h, cooling in an ice water bath, filtering, washing and vacuum drying the solid phase to obtain material C; S4. In a nitrogen atmosphere, take the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, and toluene, mix them, reflux and stir at 150°C for 6-8h, then heat to 160°C and continue stirring for 8-10h, immerse in deionized water, crush, and vacuum dry to obtain material D; S5, zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, and polycaprolactone were mixed, stirred at 60° C. for 1-2 hours, the material D was added, ultrasonically stirred for 3-4 hours, N-methylpyrrolidone was added, and stirred for 3-4 hours to obtain material E; the concentration of the ammonia water was 5 mol / L; S6, take the material B and N-methylpyrrolidone, mix, stir for 3-4h, add the material E, stir for 2-3h, filter, take the liquid phase and let it stand for degassing, then pour it onto a glass plate, dry it at 75-85°C and vacuum degree -50kPa for 20-30h, and obtain the filter membrane layer; In step S1, the dosage ratio of the polyetheretherketone and concentrated sulfuric acid is 18-22 g: 350-400 mL; the mass fraction of sulfuric acid in the concentrated sulfuric acid is 98%; In step S2, the dosage ratio of material A, dimethyl sulfoxide, N,N'-carbonyldiimidazole, and N-(3-aminopropyl)imidazole is 7-8 g: 80-90 mL: 1-1.5 g: 0.7-0.75 g; In step S3, the ratio of 3,3-bis(4-hydroxyphenyl)-3H-isobenzofuranone, 3-dimethylaminopropylamine and anhydrous ethanol is 70-80 g: 250 mL: 1 L; In step S4, the dosage ratio of the material C, 4,4'-dichlorodiphenyl sulfone, potassium carbonate, dimethylacetamide, toluene, and deionized water is 9-10 g: 7-8 g: 4-5 g: 45-50 g: 10-12 mL: 500 mL; In step S5, the dosage ratio of zirconium phosphate, anhydrous ethanol, deionized water, ammonia water, polycaprolactone, material D, and N-methylpyrrolidone is 0.6-0.8 g: 50 mL: 50 mL: 20 mL: 0.1-0.15 g: 1.2-1.4 g: 5-6 mL; In step S6, the dosage ratio of material B, N-methylpyrrolidone and material E is 1.2-1.4 g: 5-6 mL: 1.2-1.4 g.

2. A processing technology for drinking water rich in active hydrogen according to claim 1, It is characterized in that The porous ceramic sheet is a porous ceramic sheet made of magnesium tourmaline.

3. A processing technology for drinking water rich in active hydrogen according to claim 1, It is characterized in that The dosage ratio of the drinking water, the porous ceramic sheet layer and the filter membrane layer is 500L: 8-10g: 4-6g.

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