A whitening essence suitable for sensitive skin and preparation method thereof

By using natural plant extract whitening compositions and low-energy emulsification method to prepare nano-level whitening essence, the allergic and oxidative failure problems of existing whitening products are solved, and effective whitening for sensitive skin and reduced production energy consumption is achieved.

CN119074601BActive Publication Date: 2025-02-07N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411410811.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-10-10
Publication Date
2025-02-07
Estimated Expiration
2044-10-10

AI Technical Summary

Technical Problem

Existing whitening products are prone to skin allergies and oxidation failure during use, and the preparation of nanoemulsions is highly energy-consuming and difficult to meet the market's demand for safety and stability.

Method used

Natural plant extracts are used as whitening compositions to prepare nano-level whitening essence by low-energy emulsification method to ensure that the particle size is stable at the nano-level and improve the stability and absorption of active ingredients.

Benefits of technology

It achieves gentle care for sensitive skin, significantly improves the whitening effect, and reduces production energy consumption, ensuring the safety and stability of the product.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a whitening essence suitable for sensitive skin and a preparation method thereof, and belongs to the technical field of cosmetics. The whitening essence contains a whitening composition, which includes the following components: Poria cocos sclerotium extract, white water lily root extract, yacon extract, ginkgo seed extract, schisandra chinensis extract, and mullein extract. Through the synergistic effect between the six components, the whitening essence has a good whitening effect, and the whitening essence obtained by the preparation method of the present invention has a stable particle size controlled at the nanometer level, which is easier to be absorbed by the skin.
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Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to a whitening essence suitable for sensitive skin and a preparation method thereof. Background Art

[0002] Skin whitening has always been one of the hot topics of concern for Asian women. With the continuous development of society and the Internet, consumers' awareness of skin care has gradually increased, and consumers pay more attention to the safety and efficacy of cosmetics. Consumers expect skin care products to be more gentle and safe while being highly effective. Based on market demand, developers adjust the whitening ingredients of products or change the preparation method to meet market demand.

[0003] First, whitening ingredients usually achieve whitening effects by inhibiting the activity of enzymes such as tyrosinase in the melanin production pathway, reducing synthesized melanin or inhibiting DOPA self-oxidation, inhibiting the transfer of melanosomes, scavenging free radicals, accelerating skin metabolism and stratum corneum shedding. Common whitening agents include nicotinamide, vitamin C and its derivatives, phenylethylresorcinol, resveratrol, arbutin and its derivatives. However, the above whitening agents all have different degrees of irritation. Improper use can easily cause allergic phenomena such as skin redness, swelling and pain, and there is skin intolerance. For example, CN117797040B discloses a whitening nanoemulsion containing 4-butylresorcinol and a preparation method thereof. 4-butylresorcinol and nonapeptide-1, decarboxylated carnosine hydrochloride, 3-o-ethyl ascorbic acid, and tocopherol acetate are applied to the system, focusing on inhibiting the tyrosinase activity pathway to achieve whitening effects, but 4-butylresorcinol is insoluble in water, easily oxidized, and has a certain irritation.

[0004] Secondly, most whitening products on the market are applied directly to the skin by smearing. This method may cause the whitening ingredients contained in the product to be fully exposed to the air, causing them to oxidize and become ineffective. Therefore, some products may choose to use O / W or W / O packaging mode to wrap the whitening ingredients to avoid their oxidative ineffectiveness, but the particle size of the inclusions will affect the absorption of the whitening ingredients. Therefore, in order to better absorb, the particle size of the inclusions will be reduced to the nanoscale as much as possible. The nanoemulsion system can improve the solubility, stability and bioavailability of active ingredients, thereby enhancing their efficacy in cosmetics. At the same time, the nanosystem encapsulates active ingredients and can gently deliver the active ingredients into the cell to exert their effects. Given its unique properties and advantages, nanoemulsions have shown great potential in the cosmetics industry in recent years, and major raw material manufacturers and brand owners are also launching their own new nano products or new nano technologies.

[0005] Furthermore, the preparation of nanoemulsion can generally be divided into high-energy emulsification method and low-energy emulsification method. High-energy emulsification is to apply high pressure, ultrasound, micro-jet and other large fluid stresses to the two-phase liquid in order to achieve the effect of reducing the dispersed phase droplet size; for example, CN118236307A discloses an antioxidant composite nanoemulsion and its preparation method and application in cosmetics, and ascorbyl palmitate, antibacterial lipophilic modified sulfonated lignin amine, and mixed plant extracts are made into antioxidant composite nanoemulsion by high-pressure homogenization. Its homogenization process uses high pressure, which belongs to high-energy emulsification, and will cause higher energy consumption when applied to actual production. The low-energy emulsification method has less energy consumption, and the mild reaction conditions are more conducive to industrial production.

[0006] Therefore, based on the above problems, there is an urgent need to provide a whitening product that is safe to use, has good whitening effect and strong stability for market selection. Summary of the invention

[0007] The purpose of the present invention is to provide a whitening essence suitable for sensitive skin and a preparation method thereof. The active substance of the product adopts natural plant extracts and has high safety. The whitening essence prepared by the preparation method of the present invention is easier to be absorbed by the skin because its particle size is stably controlled at the nanometer level, so the whitening effect is better.

[0008] In order to achieve the above object, the present invention adopts the following technical solutions:

[0009] In a first aspect, the present invention provides a whitening composition comprising the following components: Poria cocos sclerotium extract, white water lily root extract, yacon extract, ginkgo seed extract, Schisandra chinensis extract, and verbabas extract.

[0010] Preferably, the composition with whitening effect comprises the following components in parts by weight:

[0011] 9-11 parts of Poria cocos sclerotium extract;

[0012] 9-11 parts of white water lily root extract;

[0013] 8-10 parts of yacon extract;

[0014] 8-10 parts of edamame seed extract;

[0015] 7-9 parts of Schisandra chinensis extract;

[0016] 3-6 parts of mullein extract;

[0017] The white water lily root extract is a white water lily root ethyl acetate extract and a white water lily root ethanol extract, wherein the mass ratio of the white water lily root ethyl acetate extract to the white water lily root ethanol extract is 1:0.4-0.8;

[0018] The Schisandra chinensis extract is Schisandra chinensis ethyl acetate extract.

[0019] In a second aspect, the present invention provides a whitening essence, wherein the nanoscale whitening essence comprises the following ingredients: 5-8wt% whitening composition, 0.1-0.24wt% palm oil glycerol mixed ester, 0.01-0.03wt% capryloyl glycine, 0.1-0.23wt% lauroyl wheat amino acid potassium, 0.1-0.8wt% erythritol, 0.1-1wt% polyethylene glycol-8, 0.1-1.5wt% dipropylene glycol, 0.1-0.2wt% solubilizer, 0.1-0.2wt% chelating agent, 0.1-0.7wt% preservative, 0.1-0.15wt% pH regulator, and the balance is deionized water.

[0020] Preferably, the solubilizing agent is PEG-40 hydrogenated castor oil;

[0021] Preferably, the chelating agent is disodium EDTA;

[0022] Preferably, the preservative is octanoylhydroxyvaleric acid and 1,2-hexanediol; the mass ratio of octanoylhydroxyvaleric acid to 1,2-hexanediol is 1:3-5;

[0023] Preferably, the pH adjuster is arginine.

[0024] In a third aspect, the present invention provides a method for preparing a whitening essence, the specific steps of which are as follows:

[0025] S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1;

[0026] S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2;

[0027] S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3;

[0028] S4. At room temperature, put palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, phase A1 and the remaining deionized water into an emulsifier in order, mix, stir for 45-50 minutes, and rotate at 70-90 pm; then heat to 73-75°C; add erythritol, polyethylene glycol-8 and dipropylene glycol and stir for 2-4 hours; then heat to 80-85°C; add phase A2, mix well, keep warm and stir for 15-20 minutes; then cool to 30-35°C; add phase A3 and homogenize, cool to room temperature, discharge and obtain whitening essence.

[0029] Compared with the prior art, the present invention has the following beneficial effects: the present invention prepares a nano-scale whitening essence by a specific method, which reduces energy consumption while effectively improving the stability of active ingredients; through the synergistic effect of Poria cocos sclerotium extract, white water lily root ethanol extract, white water lily root ethyl acetate extract, yacon extract, ginkgo seed extract, schisandra chinensis ethyl acetate extract, and mullein extract, the whitening effect is enhanced, and the invention has excellent production and application value. DETAILED DESCRIPTION

[0030] In order to better understand the present invention, the present invention is further described below in conjunction with specific examples, wherein the terms used in the examples are for describing specific embodiments and do not constitute limitations on the scope of protection of the present invention.

[0031] The experimental methods without specific conditions in the following tests are usually carried out under conventional conditions or the conditions recommended by the manufacturer. Unless otherwise specified, percentages and parts are calculated by weight.

[0032] Some raw materials and their sources are as follows:

[0033] Poria cocos sclerotium extract: purchased from Wuhan Kemik Biopharmaceutical Technology Co., Ltd.;

[0034] White water lily root ethyl acetate extract: purchased from Xi'an Xinhe Biotechnology Co., Ltd.;

[0035] White water lily root ethanol extract: purchased from Xi'an Xinhe Biotechnology Co., Ltd.;

[0036] Yacon extract: purchased from Shanyang Lianfeng Biotechnology Co., Ltd.;

[0037] Glycine max seed extract: purchased from Hangzhou Oushi Technology Co., Ltd.;

[0038] Schisandra chinensis ethyl acetate extract: purchased from Shanyang Lianfeng Biotechnology Co., Ltd.;

[0039] Schisandra chinensis ethanol extract: purchased from Shanyang Lianfeng Biotechnology Co., Ltd.;

[0040] Mullein extract: purchased from Xi'an Qingshuo Import and Export Trading Co., Ltd.

[0041] The weight fractions of the components in the whitening compositions of the embodiments of the present invention and the comparative examples are shown in Table 1 below:

[0042] Table 1 The weight fractions of each component in the whitening composition

[0043]

[0044]

[0045] Note: "-" means no addition, and the missing mass parts are replaced by deionized water. A whitening essence, the mass percentages of its components are shown in Table 2 below.

[0046] Table 2 Whitening essence mass percentage

[0047]

[0048]

[0049]

[0050]

[0051] The preparation methods of the above-mentioned essences 1, 4, 5 and essences ①-⑨ are as follows:

[0052] S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1;

[0053] S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2;

[0054] S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3;

[0055] S4. At room temperature, put palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, phase A1 and the remaining deionized water into an emulsifier in order, mix, stir for 45 minutes, and rotate at 70 rpm; then heat to 73°C; add erythritol, polyethylene glycol-8 and dipropylene glycol and stir for 3 hours; then heat to 85°C; add phase A2, mix well, keep warm and stir for 15 minutes; then cool to 30°C; add phase A3 and homogenize, cool to room temperature, discharge, and obtain whitening essence.

[0056] The preparation method of Essence 2 is as follows:

[0057] S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1;

[0058] S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2;

[0059] S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3;

[0060] S4. At room temperature, put palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, phase A1 and the remaining deionized water into an emulsifier in order, mix, stir for 48 minutes, and rotate at 80 rpm; then heat to 74°C; add erythritol, polyethylene glycol-8 and dipropylene glycol and stir for 2 hours; then heat to 80°C; add phase A2, mix well, keep warm and stir for 17 minutes; then cool to 33°C; add phase A3 and homogenize, cool to room temperature, discharge, and obtain whitening essence.

[0061] The preparation method of Essence 3 is as follows:

[0062] S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1;

[0063] S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2;

[0064] S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3;

[0065] S4. At room temperature, put palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, phase A1 and the remaining deionized water into an emulsifier in order, mix, stir for 50 minutes, and rotate at 90 rpm; then heat to 75°C; add erythritol, polyethylene glycol-8 and dipropylene glycol and stir for 4 hours; then heat to 83°C; add phase A2, mix well, keep warm and stir for 20 minutes; then cool to 35°C; add phase A3 and homogenize, cool to room temperature, discharge and obtain whitening essence.

[0066] Essence ⑩:

[0067] The formula of essence ⑩ is the same as that of essence 1. The difference from essence 1 is that its preparation method is as follows:

[0068] S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1;

[0069] S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2;

[0070] S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3;

[0071] S4. At 73°C, put palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, phase A1, remaining deionized water, erythritol, polyethylene glycol-8, and dipropylene glycol into an emulsifier in order, mix and stir for 3.75 hours at a speed of 70 rpm; add phase A2, mix evenly, and keep warm and stir for 15 minutes; then cool to 30°C, add phase A3 and homogenize, discharge, and obtain whitening essence ⑨.

[0072] Essence

[0073] Essence The formula used is the same as that of Essence 1. The difference from Essence 1 is that its preparation method is as follows:

[0074] S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1;

[0075] S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2;

[0076] S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3;

[0077] S4. At room temperature, put palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, remaining deionized water, erythritol, polyethylene glycol-8, dipropylene glycol, phase A2, phase A1 and phase A3 into an emulsifier, mix and stir for 4 hours at a speed of 70 rpm, then homogenize and discharge to obtain whitening essence ⑩.

[0078] Test 1: Stability evaluation test

[0079] Since only the preparation method affects its stability, only Essence 1, Essence ⑩, and Essence Conduct stability tests.

[0080] Test samples: Essence 1, Essence ⑩, Essence

[0081] Test method: 100g of essence sample was placed in a transparent PET bottle and placed at -15℃, 5℃, 25℃ and 40℃ respectively. After 0 days, 7 days and 30 days, the sample was taken out and restored to room temperature. The particle size was measured by nanoparticle size and ZETA potential analyzer (Zatasizer Nano ZS90, Malvern). At the same time, the sample was subjected to a high and low temperature cycle test of -15℃→5℃→25℃→40℃. The sample in the transparent PET bottle containing 100g of essence sample was placed in a hot and cold cycle box, and each temperature was alternated for 24 hours. After completing 6 cycles, the sample was taken out and placed back to 25℃ and then its particle size was tested, so as to evaluate the stability of the sample. The evaluation results are shown in Table 3.

[0082] Table 3 Essence particle size and stability evaluation

[0083]

[0084] As can be seen from Table 3, the particle size of Essence 1 is less than 1000nm, which belongs to the category of nano-emulsion. And after simulating storage conditions of different temperatures and high and low temperature alternation tests, the particle size is relatively stable. It also passed the stability test, but its particle size reached the micrometer level (≥1000nm). This shows that the essence prepared by the preparation method defined in the present invention has a lower particle size, is more conducive to the absorption of the active ingredients by the skin, and has excellent storage stability and high and low temperature cycle stability. In view of this result, the essence ⑩, Do not participate in the following experiments.

[0085] Experiment 2: Human safety test

[0086] 2-1. Human skin patch test

[0087] Test substances: Essence 1-5 and Essence ①-⑨.

[0088] Subject selection: Select healthy volunteers aged 21-57 years old, who voluntarily participate and sign the informed consent form and can complete the test as required during the test period. Each group has 30 subjects.

[0089] Experimental method: Select qualified patch equipment and closed patch test method, absorb 0.020mL-0.025mL (liquid) of the test substance and place it in the patch tester, apply it to the subject's back or flexor side of the forearm with low-allergenic tape, remove the test substance after 24 hours, observe and record the skin reaction 0.5, 24, and 48 hours after removal.

[0090] Result analysis: The grading of adverse skin reactions is determined according to the grading of adverse skin reactions in human trial tests specified in the "Technical Specifications for Safety of Cosmetics" (2015 edition) issued by the State Food and Drug Administration. The grading standards are shown in Table 4-1 and the results are shown in Table 4-2.

[0091] Table 4-1 Classification criteria for adverse skin reactions

[0092] Grade classification Phenomenon Level 0 No skin reaction Level 1 Light red spots on the skin Level 2 Skin erythema, infiltration, and papules Level 3 Skin erythema, edema, papules, and blisters Level 4 Skin erythema, edema, and bullae

[0093] Table 4-2 Human skin patch test results

[0094]

[0095]

[0096]

[0097] 2-2. Human test on sensitive skin

[0098] Test substances: Essence 1-5 and Essence ①-⑨.

[0099] Subject selection: healthy volunteers aged 21-44 years old, who meet the requirements of lactic acid sting test, voluntarily participate and sign the informed consent, and can complete the test as required during the test period are selected. Each group has 30 subjects.

[0100] Experimental method: Volunteers randomly divided both sides of their faces into test side and control side. After cleansing, the product was evenly applied to the facial skin of the test side according to the product usage instructions, and no product was used on the control side. After 28 days of trial, the volunteers reported local skin reactions. If there were any adverse reactions, dermatologists would evaluate the adverse reactions.

[0101] Result analysis: The grading of adverse skin reactions is determined according to the grading of adverse skin reactions in human trial tests specified in the "Technical Specifications for Safety of Cosmetics" (2015 edition) issued by the State Food and Drug Administration. The grading standards are shown in Table 4-1 and the results are shown in Table 4-3.

[0102] Table 4-3 Results of human trial tests

[0103]

[0104]

[0105] Combined with the results of the human skin patch test and the sensitive skin suitability test, during the test period, no subjects experienced adverse skin reactions to Essence 1-5 and Essence ①-⑨, indicating that Essence 1-5 and Essence ①-⑨ are safe, mild and non-irritating, and suitable for people with sensitive skin.

[0106] Test 3: Whitening efficacy test

[0107] 3.1. Skin color evaluation

[0108] Test substances: Essence 1-5 and Essence ①-⑨.

[0109] Volunteer selection: Select healthy volunteers aged 21-60 years old, voluntarily participate and sign the informed consent form, and can complete the test as required during the test period. Each group has 30 subjects.

[0110] Experimental method: Select 3 areas with an area of ​​no less than 6cm on the back of the volunteer. 2 The test area is used as the test area, negative control area and positive control area. The interval between each test area is not less than 1.0 cm, and the selected area in each test area is not less than 0.5 cm 2The melanin test area was irradiated once a day with a solar simulator (Solar light601-300) at a dose of 0.75 times MED (Minimalerythema dose) for a total of 4 consecutive days. The skin melanin period lasted for 4 days after the irradiation, and no treatment was performed. After the skin melanin period, each test area was subjected to visual skin color evaluation before product use, spectrophotometer (CM-700d) and skin red and melanin tester (Probe Mexameter MX18) tests, and the data were recorded as the initial value. On the same day, the volunteers began to use the samples according to the product usage instructions, twice a day, with an interval of no less than 4 hours each time, and applied continuously for 4 weeks. And at the time points of 1 week (1W), 2 weeks (2W), 3 weeks (3W), and 4 weeks (4W) after using the product, each test area was visually evaluated and instrumentally tested, and the data was recorded to evaluate the skin color.

[0111] Result analysis: (1) Visual skin color assessment: skin color is graded. The smaller the grade, the lighter the skin color. Skin color is evaluated from a sensory perspective.

[0112] (2) Calculate the ITA° value using the L*a*b color space value measured by the spectrophotometer. The calculation formula is as follows:

[0113]

[0114] Among them, the larger the ITA° value, the lighter the skin color, and the smaller the ITA° value, the darker the skin color.

[0115] (3) MI (Melanin index) represents the melanin index and is an important indicator for evaluating the whitening and spot-removing effects of cosmetics. The higher the MI value, the higher the melanin content in the skin and the darker the skin color. The test results are shown in Tables 5-1 and 5-2.

[0116] Table 5-1 Visual skin color assessment results

[0117]

[0118] Table 5-2 Instrument test and calculation results

[0119]

[0120]

[0121] 3.2. Skin color b* value test subjects: Essence 1-5 and Essence ①-⑨.

[0122] Volunteer selection: Select healthy volunteers aged 21-60 years old, with skin color ITA° values ​​of the test area between 20° and 41°, who can accept the tanning test using artificial light in the test area, voluntarily participate and sign the informed consent form, and can complete the test as required during the test period. Each group has 30 subjects.

[0123] Experimental method: Three test areas were selected on the back of volunteers as the test area, negative control area and positive control area, and irradiated once a day with a solar simulator (Solar light 601-300) at a dose of 0.75 times MED (Minimal erythema dose) for a total of 4 consecutive days. The skin melanization period lasted for 4 days after the irradiation, and no treatment was performed. After the skin melanization period, the b* value of the skin color of each test area was measured using a spectrophotometer Chromameter (CM-700D, Konica Minolta, Japan) as the initial value. On the same day, the volunteers began to use the sample according to the product usage method, twice a day, with an interval of no less than 4 hours each time, for 4 consecutive weeks. The skin color b* value was measured on time at 1 week (1W), 2 weeks (2W), 3 weeks (3W), and 4 weeks (4W) after using the product to evaluate the improvement of skin color. According to the International Commission on Illumination (CIE), b* represents the yellow-blue color. The larger the value, the yellower the skin color. The test results are shown in Table 5-3.

[0124] Table 5-3 Skin color b* value test results

[0125]

[0126]

[0127] According to the above test results, after using Essence 1-5 for 1 week, the subjects' visual skin color grade and ITA° value were significantly improved, and the MI value and b* value were significantly decreased, which shows that Essence 1-5 has a good whitening effect. Essences ①-⑨ selectively omit or replace the components of the whitening composition, resulting in poor whitening effect. Among them, the ITA° improvement value of essences ①-② is lower than that of essence 1 after deducting the blank (essence ⑧), and the same is true for essences ③-④ and ⑤-⑥; in essence ⑦, Schisandra chinensis was replaced, and the ethyl acetate extract of Schisandra chinensis was replaced by the ethanol extract of Schisandra chinensis. The results showed that the whitening effect achieved by using the ethanol extract was poor; in essence ⑨, the mass ratio of the ethyl acetate extract of white water lily root and the ethanol extract of white water lily root was changed, and the results showed that the whitening effect of using the ethyl acetate extract of white water lily root and the ethanol extract of white water lily root in a ratio of 1:1 was worse than the whitening effect of the composition provided by the present invention; the above results show that there is a synergistic effect between the Poria sclerotium extract, the ethyl acetate extract of white water lily root, the ethanol extract of white water lily root and the ethyl acetate extract of Schisandra chinensis in the present application and the yacon extract, the ginkgo seed extract, and the mullein extract.

[0128] Experiment 4: Self-assessment by the subjects

[0129] Test substances: Essence 1-5.

[0130] Volunteer selection: Select healthy volunteers aged 21-44 years old, who meet the requirements of lactic acid sting test, voluntarily participate and sign the informed consent form, and can complete the test as required during the test period. Each group has 30 subjects.

[0131] Experimental method: After cleansing in the morning and evening, volunteers apply an appropriate amount of the product on their face and gently pat until absorbed. The test period is 4 weeks. Volunteers observe the condition of their facial skin after cleansing every morning, and evaluate the efficacy of the sample after the test period.

[0132] Result analysis: Through questionnaire survey, we collected the subjects’ feedback on efficacy after using the samples and evaluated the product experience. The results are shown in Table 6.

[0133] Table 6 Results of self-assessment by the subjects

[0134]

[0135]

[0136] Judging from the results of the subjects' self-evaluation, the overall scores of Essences 1-5 were all high. The subjects believed that Essences 1-5 were easy to apply, easy to absorb, non-sticky, breathable and not stuffy on the skin. During the test period, they were also able to effectively improve gloss and dullness, maintain translucency, improve redness, and strengthen and stabilize the skin, indicating that this formula is safe, gentle and effective.

[0137] The embodiments described above are part of the embodiments of the present application, rather than all of the embodiments. The detailed description of the embodiments of the present application is not intended to limit the scope of the present application for protection, but merely represents the selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without making creative work are within the scope of protection of the present application.

Claims

1. A whitening composition, characterized in that: It is composed of the following components by mass: 9-11 parts of Poria cocos sclerotium extract; 9-11 parts of white water lily root extract; 8-10 parts of yacon extract; 8-10 parts of edamame seed extract; 7-9 parts of Schisandra chinensis extract; 3-6 parts of mullein extract; The white water lily root extract is white water lily root ethyl acetate extract and white water lily root ethanol extract, wherein the mass ratio of the white water lily root ethyl acetate extract to the white water lily root ethanol extract is 1:0.4-0.8; The Schisandra chinensis extract is Schisandra chinensis ethyl acetate extract.

2. A whitening essence, characterized in that: The composition comprises 5-8 wt % of the whitening composition according to claim 1.

3. The whitening essence according to claim 2, characterized in that: It also includes 0.1-0.24wt% palm oil glycerol mixed esters, 0.01-0.03wt% capryloyl glycine, 0.1-0.23wt% lauroyl wheat amino acid potassium, 0.1-0.8wt% erythritol, 0.1-1wt% polyethylene glycol-8, 0.1-1.5wt% dipropylene glycol, 0.1-0.2wt% solubilizer, 0.1-0.2wt% chelating agent, 0.1-0.7wt% preservative, 0.1-0.15wt% pH regulator, and the balance is deionized water.

4. The whitening serum according to claim 3, characterized in that: The solubilizing agent is PEG-40 hydrogenated castor oil.

5. The whitening essence according to claim 3, characterized in that: The chelating agent is disodium EDTA.

6. The whitening essence according to claim 3, characterized in that: The preservatives are capryloylhydroxyvaleric acid and 1,2-hexanediol, and the mass ratio of capryloylhydroxyvaleric acid to 1,2-hexanediol is 1:3-5.

7. The whitening essence according to claim 3, characterized in that: The pH regulator is arginine.

8. A method for preparing a whitening essence, characterized in that: The method is used for preparing the whitening essence according to any one of claims 3-7.

9. The method for preparing the whitening essence according to claim 8, characterized in that: The specific preparation steps of the whitening essence are as follows: S1, mixing the whitening composition with 1 / 3 deionized water to obtain phase A1; S2, mixing the solubilizer, preservative, chelating agent and 1 / 3 deionized water to obtain phase A2; S3, mixing the pH regulator and 1 / 6 deionized water to obtain phase A3; S4. At room temperature, palm oil glycerol mixed esters, capryloyl glycine, lauroyl wheat amino acid potassium, phase A1, and the remaining deionized water are placed in an emulsifier in order and mixed, and stirred for 45-50 minutes at a speed of 70-90 pm; Then raise the temperature to 73-75°C; add erythritol, polyethylene glycol-8, and dipropylene glycol and stir for 2-4 hours; then raise the temperature to 80-85°C; add phase A2, mix evenly, keep warm and stir for 15-20 minutes; then cool down to 30-35°C; add phase A3 and homogenize, cool to room temperature, discharge, and obtain whitening essence.

Citation Information

Patent Citations

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