An easy-to-use detection spotter

By designing mobile mechanisms and electric push rods in the chip spectrometer, the rapid installation and replacement of the spectrometer is achieved, and the cumbersome replacement process in the existing technology is solved, and the efficiency of use is improved.

CN119125598BActive Publication Date: 2025-02-14HUNAN AIBIKANG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411599801.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-11-11
Publication Date
2025-02-14
Estimated Expiration
2044-11-11

AI Technical Summary

Technical Problem

When replacing the needle of the existing chip specifier, the installation process is cumbersome and the efficiency is low, which affects the convenience of the instrument.

Method used

A convenient detection spotter was designed, and the rapid installation and replacement of the spot needle was achieved through technical means such as moving mechanisms and electric push rods. Specifically, it includes: driving the plug rod through the moving block, the rack and gear drive connection block are separated and defined, the slider is moved in the slide groove and the fixed plate is removed, so as to realize the simultaneous replacement of multiple spot needles; using servo motors and telescopic rods, it is possible to realize Quick conversion of the pointing needle position.

Benefits of technology

It realizes quick replacement and installation of sample needles, improves replacement efficiency, facilitates the use of sample needles, and reduces operational complexity.

✦ Generated by Eureka AI based on patent content.

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    Figure CN119125598B_ABST
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Abstract

The present invention belongs to the technical field of spotting instruments, and discloses a detection spotting instrument that is easy to use, including a detection operation box, a detection equipment box is arranged at the bottom of the detection operation box, a detection operation platform is arranged inside the detection operation box, a detection solution absorbing plate is arranged at the top of the detection operation platform, a detection spotting area is fixedly installed at the rear side of the detection solution absorbing plate and at the top of the detection operation platform, a cleaning and air-drying structure is arranged on one side of the detection spotting area, a first moving mechanism is arranged on both sides of the detection operation platform, a second moving mechanism is arranged at the top of one end of the first moving mechanism and at the inner wall of the detection operation box, a connecting plate is arranged at one end of the second moving mechanism, and a mounting block is arranged at the bottom of the connecting plate. By removing multiple spotting needles on the fixed plate at the same time, it is convenient to replace the spotting needles, to quickly install the spotting needles, to improve the efficiency of replacement, and to facilitate the use of the spotting instrument.
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Description

Technical Field

[0001] The invention belongs to the technical field of sample spotting instruments, and in particular relates to a detection sample spotting instrument that is easy to use. Background Art

[0002] The chip spotter is a commonly used micro-droplet dispensing pad instrument that can optimize various dispensing technologies such as piezoelectric inkjet. The chip spotter uses high-precision liquid control technology and unique software algorithms to accurately control the size and distribution of droplets at the micron level.

[0003] In the prior art, after the spotting needles have been used for a long time, multiple spotting needles need to be removed one by one for replacement and installation, which is cumbersome to install, making it difficult to improve the efficiency of rapid installation of the spotting needles and inconvenient to use the spotting instrument. Summary of the invention

[0004] The present invention aims at the problems in the prior art and proposes the following technical solutions: a detection spotting instrument that is easy to use, comprising a detection operation box, a detection equipment box is arranged at the bottom of the detection operation box, a detection operation platform is arranged inside the detection operation box, a detection solution absorbing plate is arranged at the top of the detection operation platform, a detection spotting area is fixedly installed at the rear side of the detection solution absorbing plate and at the top of the detection operation platform, a cleaning and air-drying structure is arranged on one side of the detection spotting area, a first moving mechanism is arranged on both sides of the detection operation platform, a second moving mechanism is arranged at the top of one end of the first moving mechanism and at the inner wall of the detection operation box, a connecting plate is arranged at one end of the second moving mechanism, a mounting block is arranged at the bottom of the connecting plate, a rotating block is rotatably connected to the bottom of the mounting block, a first electric push rod is fixedly installed on the top of one side of the mounting block, and a second moving mechanism is arranged at the top of one end of the first moving mechanism and at the inner wall of the detection operation box. A fixed block is provided at the bottom of an electric push rod, a mounting plate is provided on one side of the fixed block, a support plate is fixedly installed at the bottom of the mounting plate, a mounting frame is fixedly installed on one side of the mounting plate, a fixed plate is provided at the bottom of the mounting frame, a plurality of injection pumps are provided in the middle of the mounting frame, a spotting needle is provided in the middle of the fixed plate, a sliding groove is provided on the side of the mounting plate close to the fixed plate, a slider is slidably connected inside the sliding groove, a limiting groove is provided on one side of the slider, one side of the slider is fixedly installed with the fixed plate, a movable groove is provided on the top of the support plate, a limiting plate is provided inside the movable groove, one end of the limiting plate is plugged into the limiting groove, a first magnetic block is fixedly connected to the top of the other end of the limiting plate, a first connecting block is provided at the bottom of the injection pump, a second connecting block is provided at the top of the spotting needle, and a fixing structure is provided on both sides of the first connecting block and the second connecting block and inside the fixed plate;

[0005] The movable plate is located inside the movable opening, a movable opening is opened in the middle of the movable plate, the movable opening is located on the top of the fixed plate, both sides of the movable plate are movably connected to the inner wall of the movable opening, a second magnetic block is fixedly installed at the bottom of the movable plate, and the first magnetic block is magnetically connected to the second magnetic block.

[0006] As a preferred embodiment of the above technical solution, one end of the fixing plate is located at the top of the supporting plate, a mounting hole is provided on the fixing plate, the first connecting block is located at the top of the mounting hole, the top of the spotting needle and the second connecting block are located inside the mounting hole, the bottom of the first connecting block is in contact with the top of the second connecting block, slots are provided on both sides of the first connecting block and the second connecting block, the number of the fixing structure is the same as that of the injection pump and the spotting needle, the fixing structure is located on one side of the first connecting block and the second connecting block and is distributed in a linear array, and the mounting plate, the supporting plate, the fixing plate, the mounting frame, the first connecting block, the second connecting block, the injection pump and the spotting needle are symmetrically arranged around the center of the fixing block.

[0007] As a preferred embodiment of the above technical solution, the mounting plate is located at the bottom of one end of the mounting block and is fixedly installed with the rotating block away from the fixed block. Fixed grooves are provided at the bottom of the mounting block and the top of the rotating block, and a rotating structure is provided inside the fixed groove. A mounting groove is provided on the side of the rotating block close to the mounting plate, and a limiting hole is provided on one side of the fixed block. A second electric push rod is fixedly installed inside the mounting groove, and a limiting rod is fixedly installed at one end of the second electric push rod, and one end of the limiting rod passes through the mounting groove and is plugged into the mounting plate and the limiting hole.

[0008] As a preferred embodiment of the above technical solution, a movable opening is opened at one end of the fixed plate near the mounting plate, a slide groove runs through one end of the mounting plate, the slide groove is connected with the movable groove, the bottom of the limiting plate is slidably connected with the inner wall of the bottom of the movable groove, the shape of the limiting plate is U-shaped, one end of the limiting plate passes through the movable extension to the inside of the slide groove, the other end of the limiting plate is located at the bottom of the movable opening, and the top of the first magnetic block is flush with the bottom of the fixed plate.

[0009] As a preferred embodiment of the above technical solution, the fixed structure includes a first plug rod, a second plug rod is arranged at the bottom of the first plug rod, the first plug rod is plugged into the slots on both sides of the first connecting block, the second plug rod is plugged into the slots on both sides of the second connecting block, the first connecting block and the right side of the second connecting block are fixedly installed with a moving block at one end of the first plug rod and the second plug rod, the first connecting block and the left side of the second connecting block are fixedly installed with a moving plate at one end of the first plug rod and the second plug rod, the right side of the second plug rod on the right side of the second connecting block is fixedly connected with a fixed rod, one end of the fixed rod is fixedly installed with a first rack, a gear is meshed with the first rack on one side, and a second rack is meshed with the gear on one side, one end of the second rack is fixedly connected with a connecting rod, and one end of the connecting rod is fixedly connected to the second plug rod on the left side of the second connecting block.

[0010] As a preferred embodiment of the above technical solution, the moving blocks are connected by a movable rod, the first plug rod is located at the top of the fixed plate, the second plug rod is located inside the fixed plate, the moving block is located on the side of the fixed plate away from the mounting frame, the first rack and the second rack are both slidingly connected to the inner wall of the fixed plate, and a rotating rod is fixedly installed in the middle of the gear, and the upper and lower ends of the rotating rod are rotatably connected to the inner wall of the fixed plate.

[0011] As a preferred embodiment of the above technical solution, the rotating structure includes a servo motor, the output end of the servo motor is transmission-connected with a telescopic rod, two fixing holes are provided at the bottom of the fixed block, a limiting block is rotatably connected inside the fixing hole, a limiting opening is provided at the bottom of the limiting block, limiting rods are provided on both sides of the bottom end of the telescopic rod, and one end of the limiting rod passes through the fixing groove and is plugged into the limiting opening.

[0012] As a preferred embodiment of the above technical solution, the top of the servo motor is fixedly installed inside the fixed groove opened at the bottom of the fixed block, one end of the telescopic rod extends to the inner wall of the fixed groove opened at the top of the rotating block, and its bottom is rotatably connected to the inner wall of the fixed groove opened at the top of the rotating block, limiting the bottom of the rod to be fixedly installed with the inner wall of the fixed groove opened at the top of the rotating block.

[0013] The beneficial effects of the present invention are:

[0014] (1) The present invention drives the first plug rod and the second plug rod to move by moving the moving block. Under the action of the first rack, the gear and the second rack, the first connecting block and the second connecting block are no longer restricted. At the same time, the first plug rod and the second plug rod drive the moving plate to move. Under the action of the first magnetic block and the second magnetic block, the slider is no longer restricted, so that it is convenient to move the slider to drive the fixed plate to be removed from one side of the mounting plate, so that it is convenient to remove multiple spotting needles on the fixed plate at the same time, so that it is convenient to replace the spotting needles, and it is convenient to quickly install the spotting needles, improve the replacement efficiency, and facilitate the use of the spotting instrument;

[0015] (2) The present invention can drive the telescopic rod and the rotating block to rotate through a servo motor, and switch the positions of the used spotting needles on the front side of the rotating block and the unused spotting needles on the rear side, thereby reducing the number of times the spotting needles are replaced, allowing the spotting needles to quickly perform sampling and testing, and further improving the use efficiency of the spotting needles. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 What is shown is a schematic diagram of the overall structure of the embodiment;

[0017] Figure 2 What is shown is the internal structure diagram of the embodiment box;

[0018] Figure 3 Shown is a side view of the mounting block, the rotating block, the first electric push rod, the mounting plate and the mounting frame of the embodiment;

[0019] Figure 4 Shown is a cross-sectional structural diagram of the mounting block, rotating block, mounting plate, supporting plate and fixing plate of the embodiment;

[0020] Figure 5 What is shown is a structural diagram of the mounting plate, mounting frame and fixing plate of the embodiment;

[0021] Figure 6The structure diagram of the mounting plate, the fixing plate, the injection pump and the spotting needle of the embodiment is shown;

[0022] Figure 7 The embodiment shown is Figure 4 A magnified image of point A;

[0023] Figure 8 What is shown is a structural diagram of a fixing plate and a limiting plate of an embodiment;

[0024] Fig. 9 Shown is a diagram of the internal structure of a fixing plate according to an embodiment.

[0025] In the figure: 1. Detection operation box; 2. Detection equipment box; 3. Detection operation platform; 4. Detection solution extraction plate; 5. Detection spotting area; 6. Cleaning and air-drying structure; 7. First moving mechanism; 8. Second moving mechanism; 9. Connecting plate; 10. Mounting block; 11. Rotating block; 12. First electric push rod; 13. Fixed block; 14. Mounting plate; 15. Support plate; 16. Mounting frame; 17. Fixed plate; 18. Syringe pump; 19. Spotting needle; 20. Slider; 21, limiting plate; 22, first magnetic block; 23, first connecting block; 24, second connecting block; 25, second electric push rod; 26, limiting rod; 27, first plug rod; 28, second plug rod; 29, moving block; 30, moving plate; 31, fixing rod; 32, first rack; 33, gear; 34, second rack; 35, connecting rod; 36, second magnetic block; 37, servo motor; 38, telescopic rod; 39, limiting block; 40, limiting rod. DETAILED DESCRIPTION

[0026] In order to make the purpose, technical solution and advantages of the embodiments of the present invention more clear, the technical solution of the present invention will be clearly and completely described below in conjunction with the embodiments.

[0027] The present invention provides a detection sample spotting instrument which is easy to use, such as Figures 1 to 7As shown, it includes a detection operation box 1, a detection equipment box 2 is arranged at the bottom of the detection operation box 1, a detection operation platform 3 is arranged inside the detection operation box 1, a detection solution absorption plate 4 is arranged on the top of the detection operation platform 3, a detection sampling area 5 is fixedly installed on the rear side of the detection solution absorption plate 4 and located on the top of the detection operation platform 3, a cleaning and air-drying structure 6 is arranged on one side of the detection sampling area 5, first moving mechanisms 7 are arranged on both sides of the detection operation platform 3, a second moving mechanism 8 is arranged on the top of one end of the first moving mechanism 7 and located on the inner wall of the detection operation box 1, a connecting plate 9 is arranged at one end of the second moving mechanism 8, a mounting block 10 is arranged at the bottom of the connecting plate 9, a rotating block 11 is rotatably connected to the bottom of the mounting block 10, a first electric push rod 12 is fixedly installed on the top of one side of the mounting block 10, a fixing block 13 is arranged at the bottom of the first electric push rod 12, and a mounting plate 14 is arranged on one side of the fixing block 13. A support plate 15 is fixedly installed at the bottom of the mounting plate 14, a mounting frame 16 is fixedly installed on one side of the mounting plate 14, a fixing plate 17 is arranged at the bottom of the mounting frame 16, a plurality of injection pumps 18 are arranged in the middle of the mounting frame 16, a spotting needle 19 is arranged in the middle of the fixing plate 17, a sliding groove is provided on the side of the mounting plate 14 close to the fixing plate 17, a slider 20 is slidably connected inside the sliding groove, a limiting groove is provided on one side of the slider 20, and one side of the slider 20 is fixedly installed with the fixing plate 17, a movable groove is provided on the top of the support plate 15, a limiting plate 21 is arranged inside the movable groove, one end of the limiting plate 21 is plugged into the limiting groove, and a first magnetic block 22 is fixedly connected to the top of the other end of the limiting plate 21, a first connecting block 23 is arranged at the bottom of the injection pump 18, a second connecting block 24 is arranged at the top of the spotting needle 19, and a fixed structure is arranged on both sides of the first connecting block 23 and the second connecting block 24 and inside the fixing plate 17;

[0028] The movable plate 30 is located inside the movable opening. A movable opening is opened in the middle of the movable plate 30. The movable opening is located at the top of the fixed plate 17. Both sides of the movable plate 30 are movably connected to the inner wall of the movable opening. A second magnetic block 36 is fixedly installed at the bottom of the movable plate 30, and the first magnetic block 22 is magnetically connected to the second magnetic block 36.

[0029] When the first plug rod 27 and the second plug rod 28 on the left side of the first connecting block 23 and the second connecting block 24 move away from the slot, the first plug rod 27 and the second plug rod 28 on the left side of the first connecting block 23 and the second connecting block 24 drive the movable plate 30 to move inside the movable opening, and the first magnetic block 22 and the second magnetic block 36 at the bottom of the movable plate 30 drive the limiting plate 21 to move inside the movable groove, so that the limiting plate 21 moves away from the end of the first magnetic block 22 to the side away from the slider 20, so that the first connecting block 23 and the second connecting block 24 are no longer connected, and the slider 20 is no longer limited, so that it is convenient to remove the fixed plate 17 and multiple spotting needles 19 from the mounting plate 14 at the same time, reducing the steps of installation and replacement and improving usage efficiency.

[0030] The detection device box 2 controls the first moving mechanism 7 to drive the second moving mechanism 8 to move to the top of the detection solution drawing plate 4, so that the second moving mechanism 8 drives the connecting plate 9, the mounting block 10 and the rotating block 11 to move, so that the injection pump 18 and the sample spotting needle 19 move to the top of the detection solution drawing plate 4, and the first electric push rod 12 is started to drive the fixed block 13 to move downward, and the rotating structure is extended to make the rotating block 11 and the mounting plate 14 drive the injection pump 18 and the sample spotting needle 19 to move downward, and the injection pump 18 is started to absorb the solution inside the detection solution drawing plate 4 into the inside of the sample spotting needle 19, and then the first moving mechanism 7 and the second moving mechanism 8 are used to move the sample spotting needle 19 to the detection sample spotting area 5, and then the sample spotting needle 19 is moved to the detection sample spotting area 5. The first electric push rod 12 moves downward to move the sample spotting needle 19 to a suitable distance from the detection sample spotting area 5, and the movement of the first electric push rod 12 is stopped to fix the position of the sample spotting needle 19. Then, the first moving mechanism 7 and the second moving mechanism 8 are moved to spot the solution absorbed by the sample spotting needle 19. After the spotting is completed, the sample spotting needle 19 is moved to the cleaning and air-drying structure 6 by the first moving mechanism 7 and the second moving mechanism 8. The first electric push rod 12 is used to move the sample spotting needle 19 to the inside of the cleaning and air-drying structure 6 to clean the sample spotting needle 19, so as to continue to absorb different solutions for spotting. When the sample spotting needle 19 needs to be replaced, the sample spotting needle 19 is moved by the first moving mechanism 7. 9 is moved to the opening of the detection operation box 1, and the first connecting block 23 and the second connecting block 24 are no longer connected by moving the fixing structure, and the limiting plate 21 is no longer plugged into the limiting groove on one side of the slider 20, and the fixing plate 17 is moved to make the slider 20 move inside the slide groove, and the fixing plate 17 drives multiple sample needles 19 to move. When the slider 20 moves out of the slide groove, the fixing plate 17 drives the sample needles 19 to be removed from the mounting plate 14 and the support plate 15, and then the fixing plate 17 with new sample needles 19 is installed on the mounting plate 14, and the slider 20 on one side of the new fixing plate 17 is placed in the slide groove, and the fixing plate 17 drives the new sample needle 19 to move along the slide groove by moving the slider 20. When the slider 20 moves When it fits with the inner wall of one end of the slide groove, the fixed plate 17 drives the sample spotting needle 19 and the second connecting block 24 to move to the bottom of the second connecting block 24, and supports the fixed plate 17 through the support plate 15, and then moves the fixed structure to connect the first connecting block 23 with the second connecting block 24, so that the injection pump 18 is connected to the sample spotting needle 19. At the same time, the movement of the fixed structure, through the action of the first magnetic block 22, makes the limiting plate 21 inserted into the limiting groove, so that the slider 20 and the fixed plate 17 are fixed on one side of the mounting plate 14, so that the new sample spotting needle 19 is installed at the bottom of the injection pump 18, so that multiple sample spotting needles 19 can be replaced at one time, which is convenient for improving the replacement efficiency and facilitating rapid sample spotting.

[0031] like Figures 3 to 7As shown, one end of the fixing plate 17 is located at the top of the supporting plate 15, a mounting hole is provided on the fixing plate 17, the first connecting block 23 is located at the top of the mounting hole, the top of the spotting needle 19 and the second connecting block 24 are located inside the mounting hole, the bottom of the first connecting block 23 is in contact with the top of the second connecting block 24, slots are provided on both sides of the first connecting block 23 and the second connecting block 24, the number of the fixing structure is the same as that of the injection pump 18 and the spotting needle 19, the fixing structure is located on one side of the first connecting block 23 and the second connecting block 24 and is distributed in a linear array, the mounting plate 14, the supporting plate 15, the fixing plate 17, the mounting frame 16, the first connecting block 23, the second connecting block 24, the injection pump 18 and the spotting needle 19 are symmetrically arranged with the center of the fixing block 13.

[0032] The support plate 15 is used to support the fixing plate 17, so as to improve the stability of the fixing plate 17 and the sample spotting needle 19 when they are installed. The mounting hole is used to install the sample spotting needle 19 on the fixing plate 17. The slot is used to connect the first connecting block 23 and the second connecting block 24 with the fixing structure, so as to connect the first connecting block 23 and the second connecting block 24, so that the sample spotting needle 19 is connected to the injection pump 18. The mounting plate 14, the support plate 15, the fixing plate 17, the mounting frame 16, the first connecting block 23, the second connecting block 24, the injection pump 18 and the sample spotting needle 19 are symmetrically arranged around the center of the fixing block 13, so as to facilitate the rotation of the rotating structure, so that the sample spotting needle 19 on the front side and the sample spotting needle 19 on the rear side can be switched, so that the sample spotting needle 19 on one side can be used continuously after the sample spotting needle 19 on the other side is used, so as to reduce the number of replacements and improve the sample spotting effect.

[0033] like Figures 4 to 6 As shown, the mounting plate 14 is located at the bottom of one end of the mounting block 10, and is fixedly installed with the rotating block 11 away from the side of the fixed block 13. A fixing groove is provided at the bottom of the mounting block 10 and the top of the rotating block 11, and a rotating structure is arranged inside the fixing groove. A mounting groove is provided on the side of the rotating block 11 close to the mounting plate 14, and a limiting hole is provided on one side of the fixed block 13. A second electric push rod 25 is fixedly installed inside the mounting groove, and a limiting rod 26 is fixedly installed at one end of the second electric push rod 25, and one end of the limiting rod 26 passes through the mounting groove and is plugged into the mounting plate 14 and the limiting hole.

[0034] The rotating block 11 and the mounting plate 14 are driven to rotate by the rotating structure, so that the injection pump 18 and the sample spotting needle 19 on one side of the mounting plate 14 are switched positions, which is convenient for the sample spotting needle 19 on the rear side of the rotating block 11 to draw solution for sample spotting, thereby facilitating improving the efficiency of sample spotting. The limiting rod 26 is connected to the fixed block 13, so that when the second electric push rod 25 pushes the fixed block 13 to move downward, the rotating block 11 can be driven to move downward, so that the injection pump 18 and the sample spotting needle 19 on one side of the mounting plate 14 are moved downward, which is convenient for drawing solution and sample spotting. When the rotating block 11 rotates, the second electric push rod 25 drives the insertion rod to move into the mounting groove, so that the limiting rod 26 no longer limits the fixed block 13, preventing the fixed block 13 and the limiting rod 26 from limiting the rotation of the rotating block 11 when the rotating block 11 rotates, which is not convenient for the rotating block 11 to rotate, causing the sample spotting needle 19 to be switched, affecting the efficiency of sample spotting.

[0035] like Figures 7 to 9 As shown, a movable opening is opened at one end of the fixed plate 17 near the mounting plate 14, a slide groove passes through one end of the mounting plate 14, the slide groove is connected with the movable groove, the bottom of the limiting plate 21 is slidably connected with the inner wall of the bottom of the movable groove, the shape of the limiting plate 21 is U-shaped, one end of the limiting plate 21 passes through the movable extension to the inside of the slide groove, the other end of the limiting plate 21 is located at the bottom of the movable opening, and the top of the first magnetic block 22 is flush with the bottom of the fixed plate 17.

[0036] The U-shaped limiting plate 21 is used to facilitate the plugging of one end of the limiting plate 21 with the slider 20. The movable opening facilitates the movement of the fixed structure, and the top of the first magnetic block 22 is flush with the bottom of the fixed plate 17, so that the first magnetic block 22 at the other end of the limiting plate 21 is connected to the fixed structure. When the fixed structure moves, the limiting plate 21 moves along the inner wall of the movable groove, so that the limiting plate 21 can be plugged into and separated from the limiting groove on one side of the slider 20, which is convenient for the installation and replacement of the spotting needle 19 on the fixed plate 17 and is easy to use.

[0037] like Figures 8 to 9As shown, the fixed structure includes a first plug rod 27, a second plug rod 28 is arranged at the bottom of the first plug rod 27, the first plug rod 27 is plugged into the slots on both sides of the first connecting block 23, and the second plug rod 28 is plugged into the slots on both sides of the second connecting block 24. A moving block 29 is fixedly installed at one end of the first plug rod 27 and the second plug rod 28 on the right side of the first connecting block 23 and the second connecting block 24, a moving plate 30 is fixedly installed at one end of the first plug rod 27 and the second plug rod 28 on the left side of the first connecting block 23 and the second connecting block 24, a fixing rod 31 is fixedly connected to the right side of the second plug rod 28 on the right side of the second connecting block 24, and a first rack 32 is fixedly installed at one end of the fixing rod 31 A gear 33 is meshed inside one side of the first rack 32, and a second rack 34 is meshed on one side of the gear 33. A connecting rod 35 is fixedly connected to one end of the second rack 34, and one end of the connecting rod 35 is fixedly connected to the second plug rod 28 on the left side of the second connecting block 24. The moving blocks 29 are connected by a movable rod. The first plug rod 27 is located at the top of the fixed plate 17, the second plug rod 28 is located inside the fixed plate 17, and the moving block 29 is located on the side of the fixed plate 17 away from the mounting frame 16. The first rack 32 and the second rack 34 are both slidably connected to the inner wall of the fixed plate 17, and a rotating rod is fixedly installed in the middle of the gear 33. The upper and lower ends of the rotating rod are rotatably connected to the inner wall of the fixed plate 17.

[0038] By moving the moving block 29, the first plug rod 27 and the second plug rod 28 on the right side of the first connecting block 23 and the second connecting block 24 are driven to move in a direction away from the slot. Since the second plug rod 28 is located inside the fixed plate 17, when the second plug rod 28 moves, it can drive the fixed rod 31 and the first rack 32 to move, and the first rack 32 moves in a direction away from the slot on the right side of the first connecting block 23 and the second connecting block 24, so that the gear 33 drives the rotating rod to rotate, so that the second rack 34 drives the connecting rod 35 to move in the opposite direction of the first rack 32, and the connecting rod 35 is connected. The movement of the rod 35 drives the first plug rod 27 and the second plug rod 28 on the left side of the first connecting block 23 and the second connecting block 24 to move toward the second rack 34, so that the first plug rod 27 and the second plug rod 28 are no longer plugged into the slots on both sides of the first connecting block 23 and the second connecting block 24, so that the first connecting block 23 and the second connecting block 24 are no longer connected. The movable rod is connected to the moving block 29, which is convenient for simultaneously separating multiple first plug rods 27 and the second plug rod 28 from multiple first connecting blocks 23 and second connecting blocks, so that multiple spotting needles 19 can be replaced at the same time.

[0039] like Figures 4 to 6As shown, the rotating structure includes a servo motor 37, and the output end of the servo motor 37 is transmission-connected with a telescopic rod 38. Two fixing holes are provided at the bottom of the fixed block 13, and a limiting block 39 is rotatably connected inside the fixing hole. A limiting opening is provided at the bottom of the limiting block 39, and limiting rods 40 are provided on both sides of the bottom end of the telescopic rod 38. One end of the limiting rod 40 passes through the fixing groove and is plugged into the limiting opening. The top of the servo motor 37 is fixedly installed inside the fixing groove opened at the bottom of the fixed block 13, one end of the telescopic rod 38 extends to the inner wall of the fixing groove opened at the top of the rotating block 11, and its bottom is rotatably connected to the inner wall of the fixing groove opened at the top of the rotating block 11, and the bottom of the limiting rod 40 is fixedly installed to the inner wall of the fixing groove opened at the top of the rotating block 11.

[0040] When it is necessary to switch the positions of the spotting needles 19 on the front and rear sides of the rotating block 11, when the limiting rod 26 no longer limits the fixed block 13, the servo motor 37 is started to drive the telescopic rod 38 to rotate, so that the rotating block 11 rotates 180 degrees, and at the same time, the limiting rod 40 rotates inside the limiting opening inside the limiting block 39, so that the spotting needle 19 on the front side of the rotating block 11 and the spotting needle 19 on the rear side switch positions. After the conversion is completed, the second electric push rod 25 and the limiting rod 26 are connected to the fixed block 13, and the fixed block 13 and the rotating block 11 are pushed downward by the first electric push rod 12. When the rotating block 11 moves, the telescopic rod 38 The limiting rod 40 moves downward and separates from the limiting block 39, so that the mounting plate 14 drives the injection pump 18 and the sample spotting needle 19 on one side thereof to move downward to draw the solution or to spot the sample. When the solution is drawn or the sample is spotted, the second electric push rod 25 moves upward, so that the rotating block 11 drives the mounting plate 14, the injection pump 18 and the sample spotting needle 19 back to their original positions. At the same time, the telescopic rod 38 contracts, so that the limiting rod moves upward and is inserted into the limiting opening inside the limiting block 39 again, so that the rotating block 11 is fixed, so that the position of the injection pump 18 and the sample spotting needle 19 on one side of the mounting plate 14 is fixed, so as to improve the stability.

[0041] Working principle: When in use, the detection device box 2 controls the first moving mechanism 7 to drive the second moving mechanism 8 to move to the top of the detection solution drawing plate 4, so that the second moving mechanism 8 drives the connecting plate 9, the mounting block 10 and the rotating block 11 to move, so that the injection pump 18 and the spotting needle 19 move to the top of the detection solution drawing plate 4, and the first electric push rod 12 is started to drive the fixed block 13 to move downward, and the rotating block 11 and the mounting block 10 are connected to the connecting plate 9, the mounting block 10 and the rotating block 11 are connected to the connecting plate 9, the mounting block 10 and the rotating block 11 are connected to the connecting plate 9, the mounting block 10 and the rotating block 11 are connected to the connecting plate 9, the mounting block 10 and the rotating block 11 are connected to the connecting plate 9, the mounting block 10 and the rotating block 11 are connected to the connecting plate 9, the mounting block 10 and the rotating block 11 are connected to the connecting plate 9, the connecting plate 9 and the rotating block 11 are connected to the connecting plate 9, the connecting plate 9 and the rotating block 11 are connected to the connecting plate 1 ... connecting plate 11 The internal telescopic rod 38 is extended, so that the rotating block 11 and the mounting plate 14 drive the injection pump 18 and the sample spotting needle 19 to move downward, and the injection pump 18 is started to absorb the solution inside the detection solution absorption plate 4 into the inside of the sample spotting needle 19, and then the sample spotting needle 19 is moved to the detection sample spotting area 5 by the first moving mechanism 7 and the second moving mechanism 8, and the sample spotting needle 19 is moved to a suitable distance from the detection sample spotting area 5 by the first electric push rod 12. The movement of the first electric push rod 12 is stopped, so that the position of the sample spotting needle 19 is fixed, and then the solution absorbed by the sample spotting needle 19 is used for the detection sample spotting area 5 by the movement of the first moving mechanism 7 and the second moving mechanism 8. After the spotting is completed, the spotting needle 19 is moved to the cleaning and air-drying structure 6 by the first moving mechanism 7 and the second moving mechanism 8, and the spotting needle 19 is moved to the inside of the cleaning and air-drying structure 6 by the first electric push rod 12 to clean the spotting needle 19, so as to continue to draw different solutions for spotting. When the spotting needle 19 needs to be replaced, the first plugging rod 27 and the second plugging rod 28 on the right side of the first connecting block 23 and the second connecting block 24 are driven by the moving block 29 to move away from the slot. Since the second plugging rod 28 is located inside the fixed plate 17, when the second plugging rod 28 moves, it can drive the fixed rod 31 and the first rack 32 moves, the first rack 32 moves in the direction away from the slot on the right side of the first connecting block 23 and the second connecting block 24, so that the gear 33 drives the rotating rod to rotate along the inner wall of the fixing plate 17, so that the second rack 34 drives the connecting rod 35 to move in the opposite direction of the first rack 32, and the connecting rod 35 moves to drive the first plug rod 27 and the second plug rod 28 on the left side of the first connecting block 23 and the second connecting block 24 to move in the direction of the second rack 34, so that the first plug rod 27 and the second plug rod 28 are no longer plugged into the slots on both sides of the first connecting block 23 and the second connecting block 24, so that the first connecting block 23 and the second connecting block 24 are no longer connected. When the first connecting block 23 and the first plug rod 27 and the second plug rod 28 on the left side of the second connecting block 24 move away from the slot, the first connecting block 23 and the first plug rod 27 and the second plug rod 28 on the left side of the second connecting block 24 drive the movable plate 30 to move inside the movable opening, and the first magnetic block 22 and the second magnetic block 36 at the bottom of the movable plate 30 drive the limiting plate 21 to move inside the movable groove, so that the limiting plate 21 moves away from one end of the first magnetic block 22 to the side away from the slider 20, so that the limiting plate 21 is no longer plugged into the limiting groove on one side of the slider 20, and the slider 20 is no longer limited. When the first connecting block 23 and the second connecting block 24 are no longer connected,When the slider 20 is no longer restricted in the chute, the first magnetic block 22 is separated from the second magnetic block 36 by moving the fixed plate 17. When the slider 20 moves out of the chute, the fixed plate 17 drives the multiple sample needles 19 to be removed from the mounting plate 14. Then, a new fixed plate 17 and the sample needles 19 are installed on the mounting plate 14, so that the injection pump 18 is connected to the sample needles 19.

[0042] When the sample spotting needle 19 on the front side needs to be replaced after use, the second electric push rod 25 is started to drive the limit rod 26 to move, so that the limit rod 26 is away from the limit hole and no longer limits the fixed block 13. The fixed block 13 is driven by the first electric telescopic rod 38 to move upward away from the mounting plate 14. The servo motor 37 is started to drive the telescopic rod 38 to rotate, so that the rotating block 11 rotates 180 degrees. At the same time, the limiting rod 40 rotates inside the limiting opening inside the limiting block 39, so that the sample spotting needle 19 on the front side of the rotating block 11 and the sample spotting needle 19 on the rear side switch positions. After the conversion is completed, the fixed block 13 is connected by plugging the second electric push rod 25 and the limit rod 26 with the limit hole. The first electric push rod 12 pushes the fixed block 13 and the rotating block 11 to move downward. When the rotating block 11 moves, the telescopic rod 38 is extended, and the limiting rod 40 moves downward and separates from the limiting block 39, so that the mounting plate 14 drives the injection pump 18 and the sample spotting needle 19 on one side thereof to move downward to draw solution or spot.

[0043] The above embodiments are only used to illustrate the technical solutions of the present invention, but not to limit them.

Claims

1. A convenient detection sample spotting instrument, comprising a detection operation box (1), characterized in that: A detection equipment box (2) is arranged at the bottom of the detection operation box (1), a detection operation platform (3) is arranged inside the detection operation box (1), a detection solution absorbing plate (4) is arranged on the top of the detection operation platform (3), a detection sample spotting area (5) is fixedly installed on the rear side of the detection solution absorbing plate (4) and located on the top of the detection operation platform (3), a cleaning and air-drying structure (6) is arranged on one side of the detection sample spotting area (5), and first moving mechanisms (7) are arranged on both sides of the detection operation platform (3), and the first moving mechanism (7) is arranged on one side of the detection operation platform (3). A second moving mechanism (8) is arranged at the top of the end and located on the inner wall of the detection operation box (1); a connecting plate (9) is arranged at one end of the second moving mechanism (8); a mounting block (10) is arranged at the bottom of the connecting plate (9); a rotating block (11) is rotatably connected to the bottom of the mounting block (10); a first electric push rod (12) is fixedly installed at the top of one side of the mounting block (10); a fixing block (13) is arranged at the bottom of the first electric push rod (12); a mounting plate (14) is arranged at one side of the fixing block (13); and the mounting plate (14) A support plate (15) is fixedly mounted on the bottom, a mounting frame (16) is fixedly mounted on one side of the mounting plate (14), a fixing plate (17) is arranged at the bottom of the mounting frame (16), a plurality of injection pumps (18) are arranged in the middle of the mounting frame (16), a spot sample needle (19) is arranged in the middle of the fixing plate (17), a sliding groove is provided on one side of the mounting plate (14) close to the fixing plate (17), a slider (20) is slidably connected inside the sliding groove, a limiting groove is provided on one side of the slider (20), and one side of the slider (20) is connected to the fixing plate (17) fixed installation, the support plate (15) is provided with a movable groove at the top, a limiting plate (21) is arranged inside the movable groove, one end of the limiting plate (21) is plugged into the limiting groove, the other end of the limiting plate (21) is fixedly connected to the top with a first magnetic block (22), the bottom of the injection pump (18) is provided with a first connecting block (23), the top of the sample spotting needle (19) is provided with a second connecting block (24), and a fixing structure is arranged on both sides of the first connecting block (23) and the second connecting block (24) and inside the fixed plate (17); The movable plate (30) is located inside the movable opening, the movable opening is opened in the middle of the movable plate (30), the movable opening is located on the top of the fixed plate (17), both sides of the movable plate (30) are movably connected to the inner wall of the movable opening, a second magnetic block (36) is fixedly installed at the bottom of the movable plate (30), and the first magnetic block (22) is magnetically connected to the second magnetic block (36); The fixing structure comprises a first plug rod (27), a second plug rod (28) being arranged at the bottom of the first plug rod (27), the first plug rod (27) being plugged into slots on both sides of the first connecting block (23), the second plug rod (28) being plugged into slots on both sides of the second connecting block (24), a moving block (29) being fixedly mounted on one end of the first plug rod (27) and the second plug rod (28) on the right side of the first connecting block (23) and the second connecting block (24), and a moving block (29) being fixedly mounted on one end of the first plug rod (27) and the second plug rod (28) on the left side of the first connecting block (23) and the second connecting block (24). A movable plate (30) is fixedly mounted on one end of the rod (28); a fixed rod (31) is fixedly connected to the right side of the second insertion rod (28) on the right side of the second connection block (24); a first rack (32) is fixedly mounted on one end of the fixed rod (31); a gear (33) is meshed inside one side of the first rack (32); a second rack (34) is meshed on one side of the gear (33); a connecting rod (35) is fixedly connected to one end of the second rack (34); and one end of the connecting rod (35) is fixedly connected to the second insertion rod (28) on the left side of the second connection block (24).

2. A convenient detection spotting instrument according to claim 1, characterized in that: One end of the fixing plate (17) is located at the top of the supporting plate (15); a mounting hole is provided on the fixing plate (17); the first connecting block (23) is located at the top of the mounting hole; the top of the sample spotting needle (19) and the second connecting block (24) are located inside the mounting hole; the bottom of the first connecting block (23) is in contact with the top of the second connecting block (24); slots are provided on both sides of the first connecting block (23) and the second connecting block (24); the number of the fixing structures is the same as that of the injection pump (18) and the sample spotting needle (19); the fixing structures are located on both sides of the first connecting block (23) and the second connecting block (24) and are distributed in a linear array; the mounting plate (14), the supporting plate (15), the fixing plate (17), the mounting frame (16), the first connecting block (23), the second connecting block (24), the injection pump (18) and the sample spotting needle (19) are symmetrically arranged around the center of the fixing block (13).

3. The easy-to-use detection sample spotting instrument according to claim 1, characterized in that: The mounting plate (14) is located at the bottom of one end of the mounting block (10) and is fixedly mounted on the rotating block (11) at a side away from the fixed block (13). The bottom of the mounting block (10) and the top of the rotating block (11) are both provided with a fixing groove, a rotating structure is arranged inside the fixing groove, a mounting groove is arranged on a side of the rotating block (11) close to the mounting plate (14), a limiting hole is arranged on one side of the fixed block (13), a second electric push rod (25) is fixedly mounted inside the mounting groove, a limiting rod (26) is fixedly mounted on one end of the second electric push rod (25), and one end of the limiting rod (26) passes through the mounting groove and is plugged into the mounting plate (14) and the limiting hole.

4. The easy-to-use detection sample spotting instrument according to claim 1, characterized in that: The fixed plate (17) is provided with a movable opening at one end close to the mounting plate (14); the slide groove passes through one end of the mounting plate (14); the slide groove is connected to the movable groove; the bottom of the limiting plate (21) is slidably connected to the inner wall of the bottom of the movable groove; the limiting plate (21) is U-shaped; one end of the limiting plate (21) passes through the movable opening and extends into the inside of the slide groove; the other end of the limiting plate (21) is located at the bottom of the movable opening; the top of the first magnetic block (22) is flush with the bottom of the fixed plate (17).

5. The easy-to-use detection spotting instrument according to claim 1, characterized in that: The moving blocks (29) are connected via a movable rod, the first insertion rod (27) is located at the top of the fixed plate (17), the second insertion rod (28) is located inside the fixed plate (17), the moving block (29) is located on the side of the fixed plate (17) away from the mounting frame (16), the first rack (32) and the second rack (34) are both slidably connected to the inner wall of the fixed plate (17), a rotating rod is fixedly installed in the middle of the gear (33), and the upper and lower ends of the rotating rod are rotatably connected to the inner wall of the fixed plate (17).

6. The easy-to-use detection spotting instrument according to claim 3, characterized in that: The rotating structure comprises a servo motor (37), the output end of the servo motor (37) is drivingly connected to a telescopic rod (38), the bottom of the fixed block (13) is provided with two fixing holes, a limiting block (39) is rotatably connected inside the fixing holes, a limiting opening is provided at the bottom of the limiting block (39), limiting rods (40) are provided on both sides of the bottom end of the telescopic rod (38), one end of the limiting rod (40) passes through the fixing slot and is plugged into the limiting opening.

7. The easy-to-use detection sample spotting instrument according to claim 6, characterized in that: The top of the servo motor (37) is fixedly mounted inside a fixed groove opened at the bottom of the fixed block (13); one end of the telescopic rod (38) extends to the inner wall of the fixed groove opened at the top of the rotating block (11), and the bottom of the telescopic rod (38) is rotatably connected to the inner wall of the fixed groove opened at the top of the rotating block (11); the bottom of the limiting rod (40) is fixedly mounted to the inner wall of the fixed groove opened at the top of the rotating block (11).

Citation Information

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