Platelet-rich plasma preparation device and preparation method thereof

Abstract

The invention relates to the technical field of platelet-rich plasma preparation, and discloses a platelet-rich plasma preparation device and a preparation method thereof.The platelet-rich plasma preparation device comprises a split type cabin, a red blood cell cabin cover and a PRP cabin cover, and the red blood cell cabin cover and the PRP cabin cover are connected to the two ends of the split type cabin in a threaded mode; compared with a traditional mode that the locking rods are fixedly connected into the cabin, according to the preparation device, the locking rods are movably connected into the cabin, when the cabin needs to be locked, the corresponding driving blocks are pressed, the driving blocks push the locking rods, and the locking rods can be locked through the driving blocks. The locking rod is inserted into the hole of the communicated cabin for blocking and locking, the traditional mode that the length of the cabin is shortened by screwing the cabin and the locking rod is inserted into the hole of the communicated cabin for blocking and locking is changed, screwing is not needed, and the accident that plasma leaks out due to the fact that connection of the cabins falls off due to the fact that the screwing direction is wrong is avoided.

Description

Technical Field

[0001] The invention relates to the technical field of platelet-rich plasma preparation, in particular to a platelet-rich plasma preparation device and a preparation method thereof. Background Art

[0002] Platelet-rich plasma (PRP) is rich in growth factors, cytokines, antimicrobial peptides and other biologically active substances. It has the functions of promoting cell proliferation, differentiation, matrix synthesis, tissue regeneration and repair, and plays an important role in regenerative medicine. A platelet-rich plasma preparation device is needed during its preparation.

[0003] The internal locking device of the existing preparation device is fixedly connected in the cabin, and the length of the cabin is shortened by screwing the cabin, so that the locking rod is inserted into the hole connected to the cabin for sealing and locking. For example, the patent document with the announcement number CN 116651022 A discloses a platelet-rich plasma preparation device, including a first component, a second component and a third component that are detachably connected in sequence, the first component and the third component are respectively provided with a first through hole and a second through hole connected to the second component, and a blocking component is provided in the second component corresponding to the first through hole and the second through hole, and the blocking component is used to seal the first through hole and the second through hole to isolate the first component, the second component and the third component; the first component is arranged in a convergent shape at the first through hole, so that the first components on both sides of the first through hole are funnel-shaped, and the blocking component is provided with a first plug corresponding to the first through hole, and the first plug is arranged in an arc shape corresponding to the first through hole on the side close to the first through hole, and the first plug is pressed against the side of the first through hole close to the second component. The advantages of the above structure are: more complete and faster cleaning; ensuring that the stratified blood will not be squeezed and leaked into the first through hole during the sealing process, thereby improving the concentration of separated blood.

[0004] The above-mentioned preparation device uses the method of screwing the cabin to achieve the locking of the cabin, but when using this method, the preparation device must ensure that the threaded cabin part cannot be locked during production and installation, and a certain amount of space for further screwing must be reserved in advance, which causes inconvenience during production and installation. At the same time, the screwing method may cause the wrong direction of screwing, resulting in the accidental detachment of the cabin connections and plasma leakage. Summary of the invention

[0005] In view of this, the present invention provides a platelet-rich plasma preparation device and a preparation method thereof, which will not cause the accident of plasma leakage due to the wrong screwing direction causing the connection between the compartments to fall off.

[0006] The technical problem solved by the present invention is achieved by adopting the following technical solutions:

[0007] A platelet-rich plasma preparation device comprises: a split cabin (100), a red blood cell cabin cover (200) and a PRP cabin cover (300); the red blood cell cabin cover (200) and the PRP cabin cover (300) are respectively threadedly connected to two ends of the split cabin (100), and the central axes of the three coincide with each other;

[0008] The split cabin body (100) comprises three parts, namely a central cabin tube (110), a lower cabin tube (120) and an upper cabin tube (130); the lower end of the central cabin tube (110) is threadedly locked to the upper end of the lower cabin tube (120); and the lower end of the upper cabin tube (130) is threadedly locked to the upper end of the central cabin tube (110);

[0009] A locking rod (500) is movably inserted and installed in the central chamber tube (110), and a driving block for pushing the locking rod (500) is also inserted and installed on the central chamber tube (110).

[0010] Furthermore, a base plate (111) is arranged in the middle of the central compartment tube (110), a plug (112) for plugging the locking rod (500) is arranged in the middle of the base plate (111), a leakage opening (113) is opened on the base plate (111), a partition plate (114) perpendicular to the base plate (111) is fixedly arranged in the middle of the plug (112), and the partition plate (114) separates the plug (112) into two groups of semi-cylindrical plug holes;

[0011] The upper end surface of the base plate (111) is provided with a first slot block (101), and the lower end surface of the base plate (111) is provided with a second slot block (102); the grooves of the first slot block (101) and the second slot block (102) are respectively connected to two groups of semi-cylindrical sockets; and the drive blocks are respectively plugged and installed in the first slot block (101) and the second slot block (102).

[0012] Furthermore, the locking rod (500) comprises a PRP locking rod (510) movably plugged and installed at the upper end of the cannula (112) and a red blood cell locking rod (520) movably plugged and installed at the lower end of the cannula (112); the plug-in ends of the PRP locking rod (510) and the red blood cell locking rod (520) are both semi-cylindrical and are both provided with an oblique opening I;

[0013] The blocking column ends of the PRP locking rod (510) and the red blood cell locking rod (520) are respectively connected to a first spring (511) and a second spring (521).

[0014] Furthermore, the driving block comprises a first driving block (530) plugged into the first slot block (101) and a second driving block (540) plugged into the second slot block (102), and the inner ends of the first driving block (530) and the second driving block (540) are both provided with an oblique opening II, and the oblique opening I and the oblique opening II correspond to each other and cooperate with each other.

[0015] Furthermore, the lower chamber tube (120) is an hourglass-shaped structure, a first through tube (121) is provided between the two bucket-shaped structures of the lower chamber tube (120), a first retaining ring (122) is provided on the inner wall of the first through tube (121), and a second spring (521) provided on the blocking column end of the red blood cell locking rod (520) is connected to the first retaining ring (122).

[0016] Furthermore, the upper chamber pipe (130) is provided with openings (131), the two groups of openings are respectively a vent and a plasma injection port, and the upper chamber pipe (130) is covered with a rubber cap (400) for sealing the openings (131);

[0017] The upper end of the upper chamber tube (130) is provided with an inverted bucket-shaped partition structure, a second through pipe (132) is provided on the inverted bucket-shaped partition structure, a second retaining ring (133) is provided on the inner wall of the second through pipe (132), and a first spring (511) provided on the blocking column end of the PRP locking rod (510) is connected to the second retaining ring (133);

[0018] The inverted bucket-shaped partition structure is provided with a recessed area (134).

[0019] Furthermore, the PRP chamber cover (300) comprises a screw cap (310) and a silicone cover (320) connected inside the screw cap (310), the inner ring of the screw cap (310) is provided with a snap joint (311), the silicone cover (320) is provided with a snap groove (321), and the snap joint (311) is snapped into the snap groove (321).

[0020] Furthermore, a red blood cell storage chamber (600) is formed between the red blood cell chamber cover (200) and the bucket-shaped structure at the lower end of the lower chamber tube (120), a PPP storage chamber (700) is formed between the bucket-shaped structure at the upper end of the lower chamber tube (120) and the inverted bucket-shaped partition structure of the upper chamber tube (130), and a PRP storage chamber (800) is formed between the PRP chamber cover (300) and the inverted bucket-shaped partition structure of the upper chamber tube (130).

[0021] A method for preparing platelet-rich plasma, prepared by the above-mentioned platelet-rich plasma preparation device, is characterized in that it specifically comprises the following steps:

[0022] S01: Open the rubber cap (400) at the vent, and pierce the rubber cap (400) at the plasma injection port with an injection needle to inject blood;

[0023] S02: preparing a counterweight using another platelet-rich plasma preparation device;

[0024] S03: placing the platelet-rich plasma preparation device containing blood and the platelet-rich plasma preparation device for counterweight symmetrically into a medical centrifuge, and starting the first centrifugation;

[0025] S04: After the first centrifugation is completed, take out the platelet-rich plasma preparation device containing blood while maintaining the vertical state, open the rubber cap (400) at the vent, rotate the red blood cell compartment cover (200) counterclockwise, and push the PRP upward into the PPP storage chamber (700);

[0026] S05: Pressing the first driving block (530) causes the oblique opening of the first driving block (530) to push the red blood cell locking rod (520) downward, and the blocking column end of the red blood cell locking rod (520) blocks and locks the first through tube (121), and the rubber cap (400) at the vent is tightly covered;

[0027] S06: gently shake the white film layer and the clear liquid, turn the preparation device upside down, screw the PRP chamber cover (300), set the PRP preparation volume, turn the preparation device upside down and put it into the medical centrifuge, and start the second centrifugation;

[0028] S07: After the second centrifugation is completed, the preparation device is taken out and maintained in a vertical state, and the second driving block (540) is pressed so that the oblique opening of the second driving block (540) pushes the PRP locking rod (510) downward, and the blocking column end of the PRP locking rod (510) blocks and locks the second through tube (132);

[0029] S08: Shake gently, tear open the aluminum foil sealing layer on the PRP chamber cover (300), and insert a needle into the silicone cover (320) to extract the PRP in the PRP storage chamber (800).

[0030] The present invention has the following beneficial effects:

[0031] 1. A locking rod is movably installed in the central cabin tube, and a driving block for pushing the locking rod is also installed on the central cabin tube. Compared with the traditional method in which the locking rod is fixedly connected in the cabin, the preparation device connects the locking rod movably in the cabin. During the preparation of PRP, when the cabin needs to be locked, the corresponding driving block is pressed, and the driving block pushes the locking rod, so that the locking rod is inserted into the hole connecting the cabins for blocking and locking. This changes the traditional method of shortening the cabin length by screwing the cabin and inserting the locking rod into the hole connecting the cabins for blocking and locking. There is no need to screw, and there will be no accidental loss of plasma due to wrong screwing direction.

[0032] 2. Unlike the traditional preparation device, the lower end of the center compartment tube of the preparation device is threadedly locked to the upper end of the lower compartment tube, and the lower end of the upper compartment tube is threadedly locked to the upper end of the center compartment tube. There is no need to reserve the amount for further screwing in advance during production and installation, making installation more convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0034] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0035] Figure 2 It is a schematic diagram of the overall split structure of the present invention.

[0036] Figure 3 It is a schematic diagram of the overall internal structure of the present invention.

[0037] Figure 4 It is a schematic diagram of the structure of the PRP cabin cover and the upper end of the upper cabin pipe of the present invention.

[0038] Figure 5 It is a schematic diagram of the locking rod and the central compartment tube structure of the present invention.

[0039] Figure 6 It is a schematic diagram of the structure of the lower chamber tube and the red blood cell chamber cover of the present invention.

[0040] Figure 7 It is a schematic diagram of the overall cross-sectional structure of the present invention.

[0041] Figure 8 for Figure 7 Enlarged view of point A in the middle.

[0042] Fig. 9 This is a structural schematic diagram of the present invention when the first driving block is pressed to seal and lock the red blood cell storage chamber.

[0043] Fig.10 This is a structural schematic diagram of the present invention when the second driving block is pressed to seal and lock the PRP storage chamber.

[0044] Fig.11 Flow chart for the preparation of platelet-rich plasma.

[0045] In the figure: 100, split cabin; 110, central cabin tube; 111, base plate; 101, first slot block; 102, second slot block; 112, cannula; 113, leak; 114, partition plate; 120, lower cabin tube; 121, first through-tube; 122, first retaining ring; 130, upper cabin tube; 131, orifice; 132, second through-tube; 133, second retaining ring; 134, recessed area; 200, red blood cell cabin cover; 300, PRP compartment cover; 310, screw cap; 311, snap joint; 320, silicone cover; 321, snap groove; 400, rubber cap; 500, locking rod; 510, PRP locking rod; 511, first spring; 520, red blood cell locking rod; 521, second spring; 530, first drive block; 540, second drive block; 600, red blood cell storage chamber; 700, PPP storage chamber; 800, PRP storage chamber. DETAILED DESCRIPTION

[0046] In order to make the purpose, technical solutions and advantages of the implementation methods of this application clearer, the technical solutions in the implementation methods of this application will be clearly and completely described below in conjunction with the drawings in the implementation methods of this application. Obviously, the described implementation methods are part of the implementation methods of this application, not all of the implementation methods. Based on the implementation methods in this application, all other implementation methods obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0047] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for protection, but merely represents the selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present application.

[0048] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0049] In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicating orientations or positional relationships are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0050] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0051] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected or indirectly connected through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0052] In the present application, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0053] First embodiment:

[0054] Reference Figure 1-3 and Figure 7 As shown, this embodiment includes:

[0055] A split cabin body 100 and a red blood cell cabin cover 200 and a PRP cabin cover 300 threadedly connected to both ends of the split cabin body 100;

[0056] The split cabin body 100 includes a central cabin tube 110, a lower cabin tube 120 and an upper cabin tube 130. The lower end of the central cabin tube 110 is threadedly locked and connected to the upper end of the lower cabin tube 120, and the lower end of the upper cabin tube 130 is threadedly locked and connected to the upper end of the central cabin tube 110.

[0057] A locking rod 500 is movably inserted and installed in the central chamber tube 110 , and a driving block for pushing the locking rod 500 is also inserted and installed on the central chamber tube 110 .

[0058] The external thread at the lower end of the central compartment tube 110 is locked and connected with the internal thread at the upper end of the lower compartment tube 120, and the external thread at the lower end of the upper compartment tube 130 is locked and connected with the internal thread at the upper end of the central compartment tube 110, and silicone rings are connected to the lower end of the central compartment tube 110, the lower end of the lower compartment tube 120 and the lower end of the upper compartment tube 130 for connection and sealing.

[0059] A locking rod 500 is movably installed in the central chamber tube 110, and a driving block for pushing the locking rod 500 is also installed on the central chamber tube 110. Compared with the traditional method in which the locking rod 500 is fixedly connected in the chamber, the present preparation device movably connects the locking rod 500 in the chamber. During the preparation of PRP, when the chamber needs to be locked, the corresponding driving block is pressed, and the driving block pushes the locking rod 500, so that the locking rod 500 is inserted into the hole connecting the chambers for blocking and locking. This changes the traditional method of shortening the length of the chamber by screwing the chamber, and the locking rod is inserted into the hole connecting the chambers for blocking and locking. There is no need to screw, and there will be no accidental screwing direction error that causes the connection between the chambers to fall off and plasma to leak.

[0060] Unlike traditional preparation devices, the lower end of the center chamber tube 110 of the present preparation device is threadedly locked to the upper end of the lower chamber tube 120, and the lower end of the upper chamber tube 130 is threadedly locked to the upper end of the center chamber tube 110. There is no need to reserve space for further tightening in advance during production and installation, making installation more convenient.

[0061] Second embodiment:

[0062] Reference Figure 2-3 , Figure 5 , Figure 7-8 As shown, compared with the first embodiment, this embodiment further comprises: a base plate 111 is arranged in the middle of the central compartment tube 110, a plug 112 for plugging the locking rod 500 is arranged in the middle of the base plate 111, a leak 113 is opened on the base plate 111, and a partition plate 114 is fixedly arranged in the middle of the plug 112, and the partition plate 114 divides the plug 112 into two groups of semi-cylindrical plug holes;

[0063] The upper end surface of the substrate 111 is provided with a first slot block 101, and the lower end surface of the substrate 111 is provided with a second slot block 102. The grooves of the first slot block 101 and the second slot block 102 are connected by two groups of semi-cylindrical holes, and the drive blocks are respectively inserted and installed in the first slot block 101 and the second slot block 102.

[0064] Reference Figure 3-8 As shown, the locking rod 500 includes a PRP locking rod 510 movably plugged and installed at the upper end of the cannula 112 and a red blood cell locking rod 520 movably plugged and installed at the lower end of the cannula 112. The plugging ends of the PRP locking rod 510 and the red blood cell locking rod 520 are both semi-cylindrical and provided with an oblique opening I.

[0065] The blocking column ends of the PRP locking rod 510 and the red blood cell locking rod 520 are connected to a first spring 511 and a second spring 521 respectively.

[0066] Reference Figure 5 and Figure 7-8 As shown, the driving block includes a first driving block 530 inserted in the first slot block 101 and a second driving block 540 inserted in the second slot block 102. Both the first driving block 530 and the second driving block 540 are provided with an oblique opening II.

[0067] In this embodiment, the bevel I and the bevel II fit tightly together. When the driving block is pressed, the bevel I and the bevel II slide relative to each other, so that the PRP locking rod 510 moves up (the red blood cell locking rod 520 moves down); after the driving block is released, the PRP locking rod 510 or the red blood cell locking rod 520, under the elastic force of the spring, the bevel I and the bevel II slide relative to each other again, so that the driving block rebounds.

[0068] In order to avoid operational errors, a number "1" is set on the first driving block 530 and a number "2" is set on the second driving block 540 to prompt the pressing sequence.

[0069] Reference Figure 2-3 and Figure 6 As shown, the lower chamber tube 120 is an hourglass-shaped structure, a first through tube 121 is arranged between the two bucket-shaped structures of the lower chamber tube 120, a first retaining ring 122 is arranged on the inner wall of the first through tube 121, and a second spring 521 arranged on the blocking column end of the red blood cell locking rod 520 is connected to the first retaining ring 122.

[0070] Reference Figure 2-4 As shown, the upper chamber pipe 130 is provided with openings 131, and the two groups of openings are respectively a vent and a plasma injection port, and the upper chamber pipe 130 is covered with a rubber cap 400 for sealing the openings 131;

[0071] An inverted bucket-shaped partition structure is provided at the upper end of the upper chamber tube 130, a second through pipe 132 is provided on the inverted bucket-shaped partition structure, a second retaining ring 133 is provided on the inner wall of the second through pipe 132, and a first spring 511 provided on the blocking column end of the PRP locking rod 510 is connected to the second retaining ring 133;

[0072] A recessed area 134 is provided on the inverted bucket-shaped partition structure.

[0073] The arrangement of the first spring 511 and the second spring 521 enables the PRP locking rod 510 and the red blood cell locking rod 520 inserted into the cannula 112 to be positioned. Under the action of the first spring 511 and the second spring 521, the plug-in end can remain inserted into the cannula 112 to prevent it from falling out of the cannula 112. When the plug-in end is pushed by the driving block, the first spring 511 and the second spring 521 are compressed, which will not affect the blocking effect of the blocking column ends of the PRP locking rod 510 and the red blood cell locking rod 520.

[0074] Reference Figure 4 As shown, the PRP cabin cover 300 includes a screw cap 310 and a silicone cover 320 connected inside the screw cap 310 , the inner ring of the screw cap 310 is provided with a snap joint 311 , the silicone cover 320 is provided with a snap groove 321 , and the snap joint 311 is snapped into the snap groove 321 .

[0075] Reference Figure 6-7 As shown, a red blood cell storage chamber 600 is formed between the red blood cell chamber cover 200 and the bucket-shaped structure at the lower end of the lower chamber tube 120, a PPP storage chamber 700 is formed between the bucket-shaped structure at the upper end of the lower chamber tube 120 and the inverted bucket-shaped partition structure of the upper chamber tube 130, and a PRP storage chamber 800 is formed between the PRP chamber cover 300 and the inverted bucket-shaped partition structure of the upper chamber tube 130. The setting of the recessed area 134 increases the volume of the PRP storage chamber 800.

[0076] Specifically, the external thread connection between the red blood cell chamber cover 200 and the lower end of the lower chamber tube 120 is not locked. By twisting and turning the red blood cell chamber cover 200, the PRP can be pushed up to the PPP storage chamber 700. The external thread connection between the PRP chamber cover 300 and the upper end of the upper chamber tube 130 is not locked. By twisting and turning the PRP chamber cover 300, the volume of the PRP storage chamber 800 can be adjusted to achieve the setting of the PRP preparation volume. A scale is provided on the outer wall of the upper chamber tube 130 to facilitate the setting of the PRP preparation volume.

[0077] Reference Figure 9-10As shown, when the red blood cell storage chamber 600 is blocked and locked, the first driving block 530 is pressed so that the oblique opening of the first driving block 530 contacts the oblique opening of the lower end of the red blood cell locking rod 520, so that the red blood cell locking rod 520 is pushed downward, and the blocking column end of the red blood cell locking rod 520 blocks the first through tube 121, thereby achieving the blocking and locking of the red blood cell storage chamber 600. When the PRP storage chamber 800 is blocked and locked, the second driving block 540 is pressed so that the oblique opening of the second driving block 540 contacts the oblique opening of the lower end of the PRP locking rod 510, so that the PRP locking rod 510 is pushed downward, and the blocking column end of the PRP locking rod 510 blocks the second through tube 132, thereby achieving the blocking and locking of the PRP storage chamber 800.

[0078] Reference Fig.11 As shown, the present invention also provides a method for preparing platelet-rich plasma, including a platelet-rich plasma preparation device, comprising the following steps:

[0079] S01: Open the rubber cap 400 at the vent, and puncture the rubber cap 400 at the plasma injection port with an injection needle to inject blood;

[0080] S02: Use another platelet-rich plasma preparation device to prepare the counterweight. When preparing the counterweight, the error is allowed to be ±1g;

[0081] S03: placing the platelet-rich plasma preparation device containing blood and the platelet-rich plasma preparation device for counterweight symmetrically into a medical centrifuge, and starting the first centrifugation;

[0082] S04: After the first centrifugation, take out the platelet-rich plasma preparation device containing blood while maintaining the vertical state, open the rubber cap 400 at the vent, rotate the red blood cell compartment cover 200 counterclockwise, and push the PRP upward into the PPP storage chamber 700;

[0083] S05: Press the first driving block 530 so that the oblique opening of the first driving block 530 pushes the red blood cell locking rod 520 downward, and the blocking column end of the red blood cell locking rod 520 blocks and locks the first through tube 121, and the rubber cap 400 at the vent is tightly covered;

[0084] S06: Gently shake the white film layer and the clear liquid, turn the preparation device upside down, screw the PRP chamber cover 300, set the PRP preparation volume, turn the preparation device upside down and put it into the medical centrifuge, and start the second centrifugation;

[0085] S07: After the second centrifugation is completed, the preparation device is taken out and maintained in a vertical state, and the second driving block 540 is pressed, so that the oblique opening of the second driving block 540 pushes the PRP locking rod 510 downward, and the blocking column end of the PRP locking rod 510 blocks and locks the second through pipe 132;

[0086] S08: Shake gently, tear off the aluminum foil sealing layer on the PRP chamber cover 300, and insert the needle into the silicone cover 320 to extract the PRP in the PRP storage chamber 800.

[0087] When performing S01, the following details should be noted:

[0088] 1. Keep the syringe at a 30° angle to the preparation device during injection;

[0089] 2. The injection needle contacts the upper end of the PRP locking rod 510, and blood slowly flows into the PRP locking rod 510;

[0090] 3. After blood is injected, the rubber cap 400 should be tightly closed at the vent without any corners being caught or slight openings.

[0091] The first centrifugation was performed at 3200 rpm for 4 minutes, and the second centrifugation was performed at 3300 rpm for 3 minutes.

[0092] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A platelet-rich plasma preparation device, characterized in that: include: A split cabin body (100), a red blood cell cabin cover (200) and a PRP cabin cover (300); the red blood cell cabin cover (200) and the PRP cabin cover (300) are respectively threadedly connected to two ends of the split cabin body (100), and the central axes of the three coincide with each other; The split cabin body (100) comprises three parts, namely a central cabin tube (110), a lower cabin tube (120) and an upper cabin tube (130); the lower end of the central cabin tube (110) is threadedly locked to the upper end of the lower cabin tube (120); and the lower end of the upper cabin tube (130) is threadedly locked to the upper end of the central cabin tube (110); A locking rod (500) is movably inserted and installed in the central chamber tube (110), and a driving block for pushing the locking rod (500) is also inserted and installed on the central chamber tube (110).

2. A platelet-rich plasma preparation device according to claim 1, characterized in that: A base plate (111) is arranged in the middle of the central compartment tube (110), a plug (112) for plugging the locking rod (500) is arranged in the middle of the base plate (111), a leakage opening (113) is opened on the base plate (111), a partition plate (114) perpendicular to the base plate (111) is fixedly arranged in the middle of the plug (112), and the partition plate (114) separates the plug (112) into two groups of semi-cylindrical plug holes; The upper end surface of the base plate (111) is provided with a first slot block (101), and the lower end surface of the base plate (111) is provided with a second slot block (102); the grooves of the first slot block (101) and the second slot block (102) are respectively connected to two groups of semi-cylindrical sockets; and the drive blocks are respectively plugged and installed in the first slot block (101) and the second slot block (102).

3. A platelet-rich plasma preparation device according to claim 1, characterized in that: The locking rod (500) comprises a PRP locking rod (510) movably plugged and installed at the upper end of the cannula (112) and a red blood cell locking rod (520) movably plugged and installed at the lower end of the cannula (112); the plugging ends of the PRP locking rod (510) and the red blood cell locking rod (520) are both semi-cylindrical and are both provided with an oblique opening I; The blocking column ends of the PRP locking rod (510) and the red blood cell locking rod (520) are respectively connected to a first spring (511) and a second spring (521).

4. A platelet-rich plasma preparation device according to claim 2, characterized in that: The drive block comprises a first drive block (530) plugged into a first slot block (101) and a second drive block (540) plugged into a second slot block (102), wherein the first drive block (530) and the second drive block (540) are both provided with an oblique opening II at their inner ends, and the oblique opening I and the oblique opening II correspond to each other and cooperate with each other.

5. A platelet-rich plasma preparation device according to claim 3, characterized in that: The lower chamber tube (120) is an hourglass-shaped structure, a first through tube (121) is arranged between the two bucket-shaped structures of the lower chamber tube (120), a first retaining ring (122) is arranged on the inner wall of the first through tube (121), and a second spring (521) arranged on the blocking column end of the red blood cell locking rod (520) is connected to the first retaining ring (122).

6. A platelet-rich plasma preparation device according to claim 3, characterized in that: The upper chamber pipe (130) is provided with openings (131), wherein two groups of openings are respectively a vent and a plasma injection port, and the upper chamber pipe (130) is covered with a rubber cap (400) for sealing the openings (131); The upper end of the upper chamber tube (130) is provided with an inverted bucket-shaped partition structure, a second through pipe (132) is provided on the inverted bucket-shaped partition structure, a second retaining ring (133) is provided on the inner wall of the second through pipe (132), and a first spring (511) provided on the blocking column end of the PRP locking rod (510) is connected to the second retaining ring (133); The inverted bucket-shaped partition structure is provided with a recessed area (134).

7. A platelet-rich plasma preparation device according to claim 1, characterized in that: The PRP chamber cover (300) comprises a rotary cover (310) and a silicone cover (320) connected inside the rotary cover (310); the inner ring of the rotary cover (310) is provided with a clamping joint (311); the silicone cover (320) is provided with a clamping groove (321); and the clamping joint (311) is clamped in the clamping groove (321).

8. A platelet-rich plasma preparation device according to claim 1, characterized in that: A red blood cell storage chamber (600) is formed between the red blood cell chamber cover (200) and the bucket-shaped structure at the lower end of the lower chamber tube (120), a PPP storage chamber (700) is formed between the bucket-shaped structure at the upper end of the lower chamber tube (120) and the inverted bucket-shaped partition structure of the upper chamber tube (130), and a PRP storage chamber (800) is formed between the PRP chamber cover (300) and the inverted bucket-shaped partition structure of the upper chamber tube (130).

9. A method for preparing platelet-rich plasma, using a platelet-rich plasma preparation device according to any one of claims 1 to 8, characterized in that: The specific steps include: S01: Open the rubber cap (400) at the vent, and pierce the rubber cap (400) at the plasma injection port with an injection needle to inject blood; S02: preparing a counterweight using another platelet-rich plasma preparation device; S03: placing the platelet-rich plasma preparation device containing blood and the platelet-rich plasma preparation device for counterweight symmetrically into a medical centrifuge, and starting the first centrifugation; S04: After the first centrifugation is completed, take out the platelet-rich plasma preparation device containing blood while maintaining the vertical state, open the rubber cap (400) at the vent, rotate the red blood cell compartment cover (200) counterclockwise, and push the PRP upward into the PPP storage chamber (700); S05: Pressing the first driving block (530) causes the oblique opening of the first driving block (530) to push the red blood cell locking rod (520) downward, and the blocking column end of the red blood cell locking rod (520) blocks and locks the first through tube (121), and the rubber cap (400) at the vent is tightly covered; S06: Gently shake the white film layer and the clear liquid, turn the preparation device upside down, screw the PRP chamber cover (300), set the PRP preparation volume, turn the preparation device upside down and put it into the medical centrifuge, and start the second centrifugation; S07: After the second centrifugation is completed, the preparation device is taken out and maintained in a vertical state, and the second driving block (540) is pressed so that the oblique opening of the second driving block (540) pushes the PRP locking rod (510) downward, and the blocking column end of the PRP locking rod (510) blocks and locks the second through tube (132); S08: Shake gently, tear open the aluminum foil sealing layer on the PRP chamber cover (300), and insert a needle into the silicone cover (320) to extract the PRP in the PRP storage chamber (800).

Images