Precise temperature control device

Abstract

The embodiment of the invention relates to the field of experimental equipment, in particular to a precise temperature control device which comprises a shell, a driving device, a reaction device and a sealing cover. Wherein the reaction device is positioned above the shell and is used for reacting reactants in the reaction device. The sealing cover has an opening working state and a closing working state, and covers the reaction device in the closing state. The driving device is located in the shell and used for controlling the working state of the sealing cover. The precise temperature control device is compact and simple in structure, a closed reaction relation is created for the reaction device through the sealing cover, the sealing cover can be automatically controlled to be opened through the driving device, and the efficiency and experience of the experiment process are improved.

Description

Technical Field

[0001] The present invention belongs to the field of experimental equipment, and in particular, relates to a precision temperature control device. Background Art

[0002] Liquid handling workstations are widely used in experiments in fields such as biochemistry. The precision temperature control in traditional liquid handling workstations takes up a large area, and the reaction tubes are easily lifted up when the lid is opened, affecting the experimental process. Summary of the invention

[0003] The present invention is dedicated to solving the deficiencies of the prior art and aims to provide a precise temperature control device with compact structure and stable position.

[0004] In one aspect, an embodiment of the present disclosure provides a precision temperature control device, comprising:

[0005] Housing, drive device, reaction device and sealing cover;

[0006] The reaction device is located above the housing and is used to react the reactants inside;

[0007] The sealing cover has two working states: open and closed, and covers the reaction device in the closed state;

[0008] The driving device is located inside the housing and is used to control the working state of the sealing cover.

[0009] In a possible implementation, a heat dissipation device is also included;

[0010] The heat dissipation device is located in the housing and is used to control the temperature of the reaction device.

[0011] In a possible implementation, the sealing cover includes a driven device;

[0012] The driving device controls the working state of the sealing cover by controlling the driven device through a synchronous belt.

[0013] In a possible implementation, the driven device includes a rotating shaft disposed on one side inside the sealing cover, and a driven wheel that takes the rotating shaft as a central axis and is fixedly connected to the rotating shaft.

[0014] In a possible implementation, the driving device includes a stepping motor and a driving wheel, and the stepping motor drives the driving wheel to rotate during operation.

[0015] In a possible implementation, the driving wheel and the driven wheel are connected via the synchronous belt.

[0016] In a possible implementation, the sealing cover further includes a cover shell, a spring and a heat cover;

[0017] One end of the spring is fixedly connected to the cover shell, and the other end is fixedly connected to the thermal cover;

[0018] When the sealing cover is in a closed state, the thermal cover is tightly fitted to the reaction device, and the upper surface of the cover shell is located directly above the reaction device.

[0019] In a possible implementation, the reaction device includes a reaction pool and a cover plate;

[0020] The reaction pool is arranged on the upper surface of the housing and has a groove with an upward opening for accommodating the reaction medium;

[0021] The cover plate covers the groove of the reaction pool and is provided with a plurality of groups of placement holes arranged in parallel, each group of placement holes includes a preset number of placement holes arranged in sequence with the same interval.

[0022] In a possible implementation, the reaction device further includes at least one set of buckles;

[0023] At least one mounting slot group is disposed above the cover plate, which is vertical as a whole and passes through the multiple groups of storage holes. Each of the mounting slot groups includes multiple mounting slots arranged in sequence and at intervals, and each of the mounting slots is located at least on the side of one group of the storage holes.

[0024] Each group of buckles is fixedly installed in a plurality of installation slots in one installation slot group.

[0025] In a possible implementation, the buckle is a U-shaped structure consisting of a bottom and sides perpendicular to both sides of the bottom, and the sides of the buckle are parallel to the storage hole group;

[0026] A guiding and fixing component protruding relative to the side portion is provided on the outer side of the buckle side portion.

[0027] In a possible implementation, each group of the placement holes is used to place a reaction tube group including a preset number of reaction tubes, and every two reaction tubes in the reaction tube group are connected by a connector;

[0028] The guiding and fixing component comprises an upper surface and a lower surface, wherein the upper surface, the lower surface and a part of the side of the buckle form a convex structure with a triangular side surface;

[0029] When the reaction tube group is located in the placement hole group, the intersection of the upper surface and the lower surface is located above the connecting piece.

[0030] In a possible implementation, the heat dissipation device includes a Peltier and a heat dissipation device;

[0031] The Peltier is arranged above the heat dissipation device and directly below the reaction device;

[0032] The heat dissipation device is arranged inside the housing and below the Peltier.

[0033] In the disclosed embodiment, the precision temperature control device has a compact and simple structure, creates a closed reaction relationship for the reaction device through the sealing cover, and can automatically control the opening of the sealing cover through the driving device, thereby improving the efficiency and experience of the experimental process. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] This specification describes the complete and instructive disclosure of the present application, including its best mode of implementation, for those skilled in the art. This specification refers to the accompanying drawings, in which:

[0035] Figure 1 One of the structural schematic diagrams of a precision temperature control device provided in an embodiment of the present disclosure; Figure 2 A second structural schematic diagram of a precision temperature control device provided in an embodiment of the present disclosure; Figure 3 One of the schematic diagrams of the structure inside a precision temperature control device provided in an embodiment of the present disclosure;

[0036] Figure 4 The second schematic diagram of the internal structure of a precision temperature control device provided in an embodiment of the present disclosure;

[0037] Figure 5 One of the structural schematic diagrams of a reaction device provided in an embodiment of the present disclosure;

[0038] Figure 6 This is a second structural schematic diagram of a reaction device provided in an embodiment of the present disclosure.

[0039] Reference numerals:

[0040] 1. Housing; 2. Driving device; 21. Stepping motor; 22. Driving wheel; 3. Reaction device; 31. Reaction pool; 32. Cover plate; 33. Buckle; 331. Guide and fix component; 3311. Upper chamfer; 3312. Lower chamfer; 4. Sealing cover; 41. Driven wheel; 42. Heat cover; 43. Spring; 5. Heat dissipation device; 51. Peltier; 52. Heat dissipation component; 521. Radiator; 522. Fan; 6. Reaction tube; 7. Synchronous belt; 8. Connector. DETAILED DESCRIPTION

[0041] Now with reference to the embodiments of the present application in detail, one or more examples of the embodiments of the present application are illustrated in the drawings. Each example is provided to explain the present application, but not to limit the present application. In fact, it will be clear to those skilled in the art that various modifications and changes can be made in the present application without departing from the scope or spirit of the present application. For example, the features described or described as a part of an embodiment can be used together with another embodiment to produce another embodiment. As used in this specification, the terms "first", "second", etc. are used interchangeably to distinguish one component from another component without intending to indicate the position or importance of each component. As used in the specification, unless the context clearly indicates otherwise, the terms "one", "an", "the", and "said" are intended to indicate that there are one or more elements. The terms "include", "include" and "have" are intended to be inclusive, and mean that there may be other elements in addition to the listed elements.

[0042] Now referring to the drawings, in which the same numerals represent the same elements throughout the drawings, the present disclosure will be further explained below in conjunction with specific embodiments.

[0043] Figure 1 This is one of the structural schematic diagrams of a precision temperature control device provided in an embodiment of the present disclosure. Figure 1 As shown, the precision temperature control device provided by the embodiment of the present disclosure may include a housing 1, a reaction device 3 and a sealing cover 4. Among them, the housing 1 can be a rectangular parallelepiped structure, and the reaction device 3 can be arranged above the housing 1 to accommodate the reactants and react to the reactants inside. The setting position of the reaction device 3 can be the upper surface of the housing 1, or partially or completely embedded above the interior of the housing 1. The sealing cover 4 can be arranged above the upper surface of the housing 1 to ensure that the reaction device 3 is in a closed space during the operation of the reaction device 3.

[0044] Optionally, the sealing cover 4 includes two working states: open and closed. Figure 1 The working state shown is the open state of the sealing cover 4. When the sealing cover 4 is in the open state, the user can operate the reactants or reaction equipment in the reaction device 3.

[0045] Figure 2 This is a second structural diagram of a precision temperature control device provided in an embodiment of the present disclosure. Figure 2 As shown, when the sealing cover 4 is in a closed state, the sealing cover 4 covers the entire reaction device 3 to ensure that the reactants in the reaction device 3 react fully in a closed space to avoid interference from the external environment.

[0046] Optionally, the precision temperature control device of the disclosed embodiment may further include a heat sink 5, which is disposed in the housing 1 for controlling the temperature of the reaction device 3. To further improve the heat dissipation efficiency, a heat dissipation hole may be provided at a position on the housing 1 opposite to the position of the heat sink 5.

[0047] Furthermore, the precision temperature control device of the embodiment of the present disclosure may also include a driving device 2, which is located inside the housing 1 and is used to control the working state of the sealing cover 4. That is, the embodiment of the present disclosure can control the opening or closing of the sealing cover 4 through the driving device 2, without manually controlling the sealing cover 4, thereby improving work efficiency and user experience.

[0048] Figure 3 This is one of the schematic diagrams of the structure inside a precision temperature control device provided in an embodiment of the present disclosure. Figure 3 As shown, the sealing cover 4 of the disclosed embodiment also includes a driven device inside, and the driving device 2 can control the working state of the sealing cover 4 by controlling the driven device through the synchronous belt 7, that is, the driving device 2 can drive the driven device through the synchronous belt 7 to drive the sealing cover 4 to open or close.

[0049] Optionally, the driven device in the sealing cover 4 may be composed of a driven wheel 41 and a rotating shaft passing through the central axis of the driven wheel 41, and the driven wheel 41 may be one or more. The rotating shaft is fixed to one side of the inside of the sealing cover 4, and the driven wheel 41 drives the rotating shaft to rotate when the driven wheel 41 is driven by the driving device 2. Further, the rotating shaft drives one side of the sealing cover 4 to rotate to open or close the sealing cover 4. Specifically, the driving device 2 includes a stepping motor 21 and a driving wheel 22, and the driving wheel 22 is connected to the driven wheel 41 in the driven device of the sealing cover 4 through a synchronous belt 7. During the operation of the stepping motor 21, the driving wheel 22 is driven by the stepping motor 21 to rotate, and the rotation of the driving wheel 22 drives the driven wheel 41 to rotate through the synchronous belt 7, and then the fixed rotating shaft also rotates with the driven wheel 41.

[0050] In a possible implementation, the sealing cover 4 includes a cover shell, a spring 43 and a heat cover 42, wherein the heat cover 42 and the spring 43 are arranged inside the sealing cover 4, and the spring 43 can be connected to the cover shell at one end and connected to the heat cover 42 at the other end. Optionally, the spring 43 can be fixedly connected to the cover shell or the heat cover 42 by passing through the cover shell or the heat cover 42, or fixed on one side of the cover shell or the heat cover 42. Further, when the sealing cover 4 is in a closed state, the heat cover 42 is tightly fitted with the reaction device 3, and the upper surface of the shell cover is located directly above the reaction device 3. In order to further play a sealing role and ensure that the reaction environment of the reaction device 3 is sealed, a sealing structure such as a sealing ring or a sealing pad can also be provided around the heat cover 42. Optionally, the heat cover 42 can also include a heating film and a temperature sensor, the heating film is used to further heat the reaction environment of the reaction device 3, and the temperature sensor can be used for precise temperature control to prevent condensed water from accumulating on the upper surface of the heat cover 42, thereby affecting the reaction process.

[0051] Furthermore, the sealing cover 4 may also have a quick-release function, and the thermal cover 42 may be quickly removed when the sealing cover 4 is in the open state, and components such as the thermal cover 42, the heating film, and the sealing pad may be replaced, and the thermal cover 42 may be easily cleaned. The quick-release function may further improve the overall application experience of the sealing cover 4 and the precision temperature control device.

[0052] Figure 4 This is a second schematic diagram of the structure of a precision temperature control device provided in an embodiment of the present disclosure. Figure 4 As shown, the heat sink 5 in the precision temperature control device of the embodiment of the present disclosure includes a Peltier 51 and a heat dissipation device. Among them, the Peltier 51 is arranged above the heat sink 5, and the installation position is located directly below the reaction device 3. For example, the Peltier 51 can be directly embedded and installed on the upper surface of the housing 1, or fixed inside the housing 1 by a bracket or the like and located directly below the reaction device 3. The heat sink 5 is arranged inside the housing 1, below the Peltier 51. Optionally, the heat sink 5 may include at least one heat dissipation component 52 such as a fan 522 and a radiator 521. The setting direction of the Peltier 51 can be the cold side facing up and the hot side facing down. When the reaction device 3 heats the reactants therein, the Peltier 51 and the heat sink 5 are not turned on to increase the temperature in the reaction device 3. When the reaction device 3 cools the reactants therein, the Peltier 51 and the heat sink 5 are turned on, and the reaction device 3 is cooled by the cold side of the Peltier 51.

[0053] Optionally, the reaction device 3 may include a reaction pool 31 and a cover plate 32, wherein the reaction pool 31 is arranged above the housing 1 and has a groove with an opening facing upward, and the groove is used to accommodate the reaction medium. The cover plate 32 covers the groove of the reaction pool 31 and is provided with a plurality of groups of placement holes arranged in parallel, and each group of placement holes includes a preset number of placement holes arranged in sequence with the same interval. The placement hole is used to place a reaction tube 6 containing a reactant. Among them, the reaction medium can be any heat-conducting medium such as water and oil, which is used to cool the placed reactant through the heat conduction of the Peltier 51, or to heat the placed reactant through the heat conduction of the heating film. Alternatively, the reaction medium may also include at least two chemicals that generate heat after the reaction to cool the placed reactant.

[0054] Furthermore, temperature sensors may be provided on both sides of the reaction pool 31 for real-time temperature monitoring during the reaction process to achieve precise temperature control and avoid experimental failure due to temperature changes during the reaction process. Optionally, the precision temperature control device in the disclosed embodiment may also include a control device connected to the temperature sensor, for receiving temperature information sent by the temperature sensors provided on both sides of the sealing cover 4 and / or the reaction pool 31, and when the temperature fluctuates unexpectedly, the heat dissipation device 5 may be controlled to adjust the temperature, or the drive device 2 may be controlled to open the sealing cover 4.

[0055] Figure 5 This is one of the structural schematic diagrams of a reaction device provided in an embodiment of the present disclosure. Figure 5 As shown, the reaction device 3 also includes at least one group of buckles 33. At least one mounting slot group that is vertical as a whole and penetrates multiple groups of storage hole groups is provided above the cover plate 32, and each mounting slot group includes multiple mounting slots arranged in sequence and at intervals, and each mounting slot is at least located on the side of a group of storage hole groups. In other words, each mounting slot is arranged on both sides of the intersection of the storage hole group and the mounting slot group, and the mounting slot group can be provided with a mounting slot on both sides of each position intersecting with the storage hole. Optionally, each group of buckles 33 is fixedly installed in multiple mounting slots in one mounting slot group, one buckle 33 is installed in one mounting slot, and the number of buckles 33 matches the number of mounting slots in the mounting slot group.

[0056] Further, each group of placement holes is used to place a group of reaction tubes 6 including a preset number of reaction tubes 6, and every two reaction tubes 6 in the reaction tube group 6 are connected by a connector 8. Optionally, the reaction tubes 6 in the reaction tube group 6 can be PCR reaction tubes 6.

[0057] Figure 6 This is a second schematic diagram of a reaction device provided in an embodiment of the present disclosure. Figure 6As shown, the buckle 33 is a U-shaped structure consisting of a bottom and sides perpendicular to the bottom. The sides of the buckle 33 are parallel to the storage hole group, that is, the two sides of the U-shaped structure are parallel to the storage hole group. The outer side of the side of the buckle 33 is provided with a guide fixing component 331 protruding from the opposite side. Optionally, the bottom of the buckle 33 is provided with a fixing hole for fixed connection with the cover plate 32.

[0058] Further, the guide fixing component 331 includes an upper surface and a lower surface, and the upper surface, the lower surface and the part of the side of the buckle 33 form a convex structure with a triangular side surface. When the reaction tube 6 group is located in the storage hole group, the intersection of the upper surface and the lower surface is located above the connector 8. In other words, the upper surface of the guide fixing component 331 and the side of the buckle 33 form an upper chamfer 3311, and when the user places the reaction tube 6 group in the storage hole group, the upper chamfer 3311 of the buckle 33 plays a guiding role. The upper surface of the guide fixing component 331 and the side of the buckle 33 form a lower chamfer 3312, and when the sealing cover 4 is opened, the lower chamfer 3312 can prevent the reaction tube 6 group from being lifted up by limiting the upward movement of the connector 8.

[0059] Based on the above technical features, the embodiment of the present disclosure provides a compact precise temperature control device structure, and improves the overall working efficiency of the precise temperature control device by driving the sealing cover 4 to open and close through the driving device 2, and a buckle 33 is arranged above the cover plate 32 to prevent the reaction tube 6 from being lifted up when the sealing cover 4 is opened. At the same time, the embodiment of the present disclosure also accurately controls the reaction environment temperature of the reaction tube 6 through the arrangement of the heat dissipation device 5 and the temperature sensor, and further controls the sealing cover 4 to automatically open when there is a problem with the ambient temperature through the driving device 2 to avoid accidents.

[0060] This specification uses embodiments to disclose the present application, including the best embodiment, and also enables those skilled in the art to practice the present application, including making and using any device or system and performing any incorporated method. The embodiments of the present application and the technical solutions obtained by slightly changing the embodiments are all within the protection scope of the present application.

Claims

1. A precision temperature control device, characterized in that: include; Housing, drive device, reaction device and sealing cover; The reaction device is located above the housing and is used to react the reactants inside; The sealing cover has two working states: open and closed, and covers the reaction device in the closed state; The driving device is located inside the housing and is used to control the working state of the sealing cover.

2. The device according to claim 1, characterized in that Also includes a heat sink; The heat dissipation device is located in the housing and is used to control the temperature of the reaction device.

3. The device according to claim 1, characterized in that The sealing cover includes a driven device; The driving device controls the working state of the sealing cover by controlling the driven device through a synchronous belt.

4. The device according to claim 3, characterized in that The driven device comprises a rotating shaft arranged at one side of the sealing cover, and a driven wheel which takes the rotating shaft as a central axis and is fixedly connected to the rotating shaft.

5. The device according to claim 4, characterized in that The driving device comprises a stepping motor and a driving wheel, and the stepping motor drives the driving wheel to rotate during operation.

6. The device according to claim 5, characterized in that The driving wheel and the driven wheel are connected through the synchronous belt.

7. The device according to claim 1, characterized in that The sealing cover also includes a cover shell, a spring and a thermal cover; One end of the spring is fixedly connected to the cover shell, and the other end is fixedly connected to the thermal cover; When the sealing cover is in a closed state, the thermal cover is tightly fitted to the reaction device, and the upper part of the cover shell is located directly above the reaction device.

8. The device according to claim 1, characterized in that The reaction device comprises a reaction pool and a cover plate; The reaction pool is arranged above the housing and has a groove with an upward opening for accommodating a reaction medium; The cover plate covers the groove of the reaction pool and is provided with a plurality of groups of placement holes arranged in parallel, each group of placement holes includes a preset number of placement holes arranged in sequence with the same interval.

9. The device according to claim 8, characterized in that The reaction device also includes at least one set of buckles; At least one mounting slot group is disposed above the cover plate, which is vertical as a whole and penetrates through the multiple groups of storage holes. Each of the mounting slot groups includes a plurality of mounting slots arranged in sequence and at intervals, and each of the mounting slots is located at least on the side of one group of the storage holes. Each group of buckles is fixedly installed in a plurality of installation slots in one installation slot group.

10. The device according to claim 9, characterized in that The buckle is a U-shaped structure consisting of a bottom and sides perpendicular to the bottom, and the sides of the buckle are parallel to the storage hole group; A guiding and fixing component protruding relative to the side portion is provided on the outer side of the buckle side portion.

11. The device according to claim 10, characterized in that Each group of the placement holes is used to place a reaction tube group including a preset number of reaction tubes, and every two reaction tubes in the reaction tube group are connected by a connector; The guiding and fixing component comprises an upper surface and a lower surface, wherein the upper surface, the lower surface and a part of the side of the buckle form a convex structure with a triangular side surface; When the reaction tube group is located in the placement hole group, the intersection of the upper surface and the lower surface is located above the connecting piece.

12. The device according to claim 2, characterized in that The heat dissipation device includes a Peltier and a heat dissipation device; The Peltier is arranged above the heat dissipation device and is located directly below the reaction device; The heat dissipation device is arranged inside the housing and below the Peltier.

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