Dispersible oil suspending agent as well as preparation method and application thereof

Abstract

The invention relates to the technical field of pesticide preparations, and discloses a dispersible oil suspending agent as well as a preparation method and application thereof. The dispersible oil suspending agent takes emamectin benzoate and lufenuron as active ingredients, and further comprises a dispersion medium, a dispersing agent, a wetting agent, an emulsifying agent, a thickening agent and a stabilizing agent, wherein the dispersion medium is methyl esterified vegetable oil; the dispersing agent is sulfosuccinate and / or alkyl naphthalene sulfonate; the wetting agent is polyethylene glycol fatty acid ester and / or alkylphenol polyoxyethylene ether phosphate; and the emulsifier is fatty alcohol-polyoxyethylene ether. Compared with an existing water suspending agent or water dispersible granules, the dispersible oil suspending agent has the advantages that the surface tension and the contact angle of liquid medicine can be remarkably reduced, the deposition amount on leaf surfaces is increased, the control effect on crop targets is improved, the spraying adhesion rate of the liquid medicine is increased, rain wash resistance is achieved, the permeability to target insect bodies is good, loss of effective components is reduced, and the effect is good. Pesticide spraying times are reduced, and cost investment is reduced.

Description

Technical Field

[0001] The invention relates to the technical field of pesticide preparations, and in particular to a dispersible oil suspension, a preparation method and an application thereof. Background Art

[0002] In the field of pesticide preparation production, organic solvents are often used as dispersion media. The main solvents generally used are xylene, methanol, N,N-dimethylformamide and cyclohexanone. These organic solvents are harmful to the human body during the preparation, processing and use of pesticide preparations, and are also toxic to humans and animals and have a relatively large impact on environmental pollution. In addition, toluene and xylene are also highly volatile and flammable, and there are safety hazards during transportation and use.

[0003] Emamectin benzoate (abbreviated as Emamectin benzoate), English common name: Emamectin Benzoate, chemical name is N-(N-cyano-ethylimino)-N-methyl-2-chloropyridine-5-methylamine, molecular formula is C 56 H 81 NO 15 , relative molecular weight 1008.24, CAS number: 137512-74-4, chemical structure as shown in formula (I):

[0004]

[0005] Emamectin benzoate has the characteristics of high efficiency, low toxicity, low residue and pollution-free. It has both stomach poison and contact killing effects, and does not harm beneficial insects in the process of pest control. It is an environmentally friendly low-toxic pesticide.

[0006] Lufenuron, English common name: Lufenuron, chemical name is 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea, molecular formula is C 17 H8Cl2F8N2O3, relative molecular weight 511.15, CAS number: 103055-07-8, chemical structure as shown in formula (II):

[0007]

[0008] Lufenuron is a new type of benzoylurea insecticide and acaricide. It is an insect growth regulator with chitin synthesis inhibition effect. It has a unique insecticidal mechanism and kills pests by acting on insect larvae and preventing the molting process. Lufenuron is mainly used to control pests such as diamondback moth, bean pod borer, thrips, caterpillar, cotton bollworm, etc. It is safe for crops and can be used for crops such as corn, vegetables, citrus, cotton, potatoes, grapes, soybeans, etc. Its advantage is that it can control pests that are resistant to synthetic pyrethroids and organophosphorus pesticides, and is suitable for integrated pest management.

[0009] After investigation, it was found that the pesticide formulations containing emamectin benzoate and lufenuron on the market currently include microemulsions, water suspensions and water dispersible granules. Microemulsions are stable, have good adhesion, and are not easily washed away by rain, but because they contain organic solvents such as hydrocarbons, they are not friendly to the environment and have harmful effects on the human body; water suspensions and water dispersible granules are green and environmentally friendly, but their kinetic systems are relatively unstable and the application effect is relatively slow.

[0010] Dispersible oil suspension concentrate is a kind of solid pesticide active ingredient insoluble in oil medium dispersed in non-aqueous medium to form a highly dispersed and stable suspension system. The non-aqueous medium used in this dosage form is generally an environmentally friendly oil-based dispersion medium, such as vegetable oil, methylated vegetable oil and mineral oil. The use of oil-based dispersion medium in the production of formulations can avoid harm to the human body (including but not limited to corrosion, burning, poisoning, etc.), and can reduce the risk of harmful substances remaining on crops when applying pesticides.

[0011] There is no dispersible oil suspension containing emamectin benzoate and lufenuron as active ingredients in the prior art. Summary of the invention

[0012] The purpose of the present invention is to overcome the problems existing in the prior art and to provide a dispersible oil suspension containing avermectin benzoate and lufenuron and a preparation method and application thereof.

[0013] The invention processes avermectin benzoate and lufenuron into a dispersible oil suspension and applies it to preventing and controlling crop pests. The provided dispersible oil suspension has strong permeability, is resistant to rainwater erosion, and has a long lasting effect, which can reduce the number of times of drug use and save costs.

[0014] In order to achieve the above-mentioned object, the first aspect of the present invention provides a dispersible oil suspension, wherein the dispersible oil suspension contains emamectin benzoate and lufenuron as active ingredients, and further comprises a dispersion medium, a dispersant, a wetting agent, an emulsifier, a thickener and a stabilizer;

[0015] Wherein, the dispersion medium is methylated vegetable oil; the dispersant is sulfosuccinate and / or alkylnaphthalenesulfonate; the wetting agent is polyethylene glycol fatty acid ester and / or alkylphenol polyoxyethylene ether phosphate; and the emulsifier is fatty alcohol polyoxyethylene ether.

[0016] The second aspect of the present invention provides a method for preparing the dispersible oil suspension according to the first aspect, wherein the method comprises the following steps:

[0017] (1) mixing a dispersion medium, a dispersant, a wetting agent and an emulsifier to obtain a mixed solution;

[0018] (2) adding emamectin benzoate, lufenuron, a thickener and a stabilizer to the mixed solution obtained in step (1), and obtaining a dispersion by shearing;

[0019] (3) sand-milling the dispersion obtained in step (2) to obtain the dispersible oil suspension.

[0020] The third aspect of the present invention provides use of the dispersible oil suspension concentrate according to the first aspect or the dispersible oil suspension concentrate obtained by the preparation method according to the second aspect in controlling lepidoptera, homoptera, diptera and thrips pests in crops.

[0021] Through the above technical solution, the beneficial technical effects achieved by the present invention are as follows:

[0022] (1) The present invention achieves a synergistic effect of components in pest control by screening adjuvants and dispersing media and selecting dosage forms. The invention is resistant to rain erosion and has a longer lasting effect, thus helping farmers reduce the amount and frequency of drug use and lowering costs.

[0023] (2) The present invention uses safe and environmentally friendly methylated vegetable oil as the dispersion medium, which effectively avoids the harm (or damage) to the human body and the environment that may be easily caused during the production of the preparation.

[0024] (3) Compared with the existing water suspension concentrate or water dispersible granules, the dispersible oil suspension concentrate of the present invention can significantly reduce the surface tension and contact angle of the pesticide solution, increase the deposition amount on the leaf surface, improve the control effect on the crop target, increase the spraying adhesion rate of the pesticide solution, resist rain erosion, have good permeability to the target insect body, reduce the loss of effective ingredients, reduce the number of pesticide spraying times, and reduce cost investment. DETAILED DESCRIPTION

[0025] The endpoints and any values ​​of the ranges disclosed in this article are not limited to the precise ranges or values, and these ranges or values ​​should be understood to include values ​​close to these ranges or values. For numerical ranges, the endpoint values ​​of each range, the endpoint values ​​of each range and the individual point values, and the individual point values ​​can be combined with each other to obtain one or more new numerical ranges, which should be considered as specifically disclosed in this article.

[0026] The first aspect of the present invention provides a dispersible oil suspension, which contains emamectin benzoate and lufenuron as active ingredients, and further comprises a dispersion medium, a dispersant, a wetting agent, an emulsifier, a thickener and a stabilizer;

[0027] Wherein, the dispersion medium is methylated vegetable oil; the dispersant is sulfosuccinate and / or alkylnaphthalenesulfonate; the wetting agent is polyethylene glycol fatty acid ester and / or alkylphenol polyoxyethylene ether phosphate; and the emulsifier is fatty alcohol polyoxyethylene ether.

[0028] Based on the good activity of emamectin benzoate and lufenuron and the environmental friendliness of the dispersible oil suspension, the inventors of the present invention determined to develop a dispersible oil suspension with emamectin benzoate and lufenuron as active ingredients in the early stage of research and development. However, during the research and development process, the inventors found that the dispersible oil suspension prepared by selecting conventional raw materials was not satisfactory in terms of pest control effect. After further research and development, the inventors accidentally discovered that emamectin benzoate and lufenuron were prone to oil separation and bottoming in the dispersible oil suspension, thereby preventing its pest control effect from being improved.

[0029] In the subsequent research and development process, the inventors creatively optimized the types of raw materials and finally developed a method using methylated vegetable oil as the dispersion medium, sulfosuccinates and / or alkylnaphthalene sulfonates as dispersants, polyethylene glycol fatty acid esters and / or alkylphenol polyoxyethylene ether phosphates as wetting agents, and fatty alcohol polyoxyethylene ethers as emulsifiers. Through the screening of auxiliary agents and dispersion media, the protective effect of the finally prepared dispersible oil suspension was unexpectedly improved.

[0030] In some embodiments of the present invention, the methylated vegetable oil is selected from at least one of methylated peanut oil, methylated corn oil, methylated soybean oil and methylated palm oil, preferably methylated peanut oil. Methylated peanut oil has a wide range of sources, good biodegradability, non-toxicity, lower viscosity than other dispersion media, and can return to normal at 0°C after solidification at extreme temperatures, has good crop development performance, and good biological targeting.

[0031] In some embodiments of the present invention, the dispersant is sulfosuccinate, and the wetting agent is polyethylene glycol fatty acid ester.

[0032] In some embodiments of the present invention, the thickener is selected from at least one of organic bentonite, diatomaceous earth, attapulgite, fumed silica, polyvinyl pyrrolidone, methyl cellulose, polyvinyl alcohol, xanthan gum and magnesium aluminum silicate, preferably organic bentonite and fumed silica.

[0033] In some embodiments of the present invention, the stabilizer is an anti-emamectin benzoate decomposition agent produced by Shenzhen Langtai Biotechnology Co., Ltd. D902.

[0034] In some embodiments of the present invention, the active ingredient accounts for 10-25% of the total weight of the dispersible oil suspension, preferably 15%.

[0035] In some embodiments of the present invention, the emamectin benzoate accounts for 1-5% of the total weight of the dispersible oil suspension, preferably 3%.

[0036] In some embodiments of the present invention, the lufenuron accounts for 8-20% by weight of the total weight of the dispersible oil suspension concentrate, preferably 12%.

[0037] The invention mixes two active ingredients in a dispersible oil suspension in a reasonable ratio, thereby enhancing the medicinal effect of the insecticide and expanding the pest control spectrum.

[0038] In some embodiments of the present invention, the dispersible oil suspension comprises the following components in parts by weight: 1-5 parts of emamectin benzoate, 8-20 parts of lufenuron, 52.2-69.7 parts of dispersion medium, 5-8 parts of dispersant, 5-6 parts of wetting agent, 4-8 parts of emulsifier, 2-2.5 parts of thickener and 0.3 parts of stabilizer.

[0039] In some embodiments of the present invention, the dispersible oil suspension comprises the following components in parts by weight: 3 parts of emamectin benzoate, 12 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, and an anti-emamectin benzoate decomposition agent. D9020.3 parts, methyl ester peanut oil is made up to 100 parts (i.e. 64.7 parts).

[0040] In some embodiments of the present invention, the microparticle size D90 of the dispersible oil suspension is less than 5 microns.

[0041] The present invention provides a method for preparing the dispersible oil suspension according to the first aspect, wherein the method comprises the following steps:

[0042] (1) mixing a dispersion medium, a dispersant, a wetting agent and an emulsifier to obtain a mixed solution;

[0043] (2) adding emamectin benzoate, lufenuron, a thickener and a stabilizer to the mixed solution obtained in step (1), and obtaining a dispersion by shearing;

[0044] (3) sand-milling the dispersion obtained in step (2) to obtain the dispersible oil suspension.

[0045] The production equipment required for the preparation of the dispersible oil suspension includes: a preparation kettle with a shearing machine, a transmission, a polypropylene filter, a pump, a pneumatic diaphragm pump, a metering scale, a transfer tank, a horizontal sand mill, and a cooler. One or more of the following.

[0046] In some embodiments of the present invention, the mixed solution is obtained by stirring in step (1), and the stirring speed is 60r / min and the time is 10-15min.

[0047] In some embodiments of the present invention, the shearing speed in step (2) is 3000-3500 r / min and the time is 10-20 min.

[0048] In some embodiments of the present invention, the discharge flow rate of the sand mill in step (3) is 360 kg / h, and the material temperature in the grinding chamber of the sand mill is below 35°C.

[0049] The third aspect of the present invention provides use of the dispersible oil suspension concentrate according to the first aspect or the dispersible oil suspension concentrate obtained by the preparation method according to the second aspect in controlling lepidoptera, homoptera, diptera and thrips pests in crops.

[0050] In some embodiments of the present invention, the insect pest is selected from at least one of stem borers, cotton bollworms, cotton aphids, beet armyworms, Spodoptera litura, cabbage loopers, leaf miners, red spiders, rust ticks, whiteflies and thrips.

[0051] In some embodiments of the present invention, the dispersible oil suspension is diluted with water and then sprayed, with an application amount of 10-14 mL / mu, preferably 12.5 mL / mu.

[0052] The present invention will be described in detail below through examples.

[0053] In the following examples and comparative examples, if no specific conditions are specified, the experiments were carried out under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used, if no manufacturer is specified, are all conventional products that can be obtained through commercial channels.

[0054] In the following examples or comparative examples, the preparation method of the dispersible oil suspension is as follows:

[0055] At room temperature and pressure, the dispersion medium, dispersant, wetting agent and emulsifier are first pumped into the kettle with a pump according to the proportion of each formula, and stirred evenly at a stirring speed of 60r / min and a stirring time of 10min; then emamectin benzoate and lufenuron as well as a thickener and a stabilizer are added, and then the materials are sheared in the kettle and in the pipeline, with a total of two-level shearing for 15min to make the materials homogeneous and dispersed; finally, the circulating water is turned on, and the materials are sand-milled for three levels with a sand mill. The temperature is controlled below 35°C, the discharge flow rate is 360kg / h, and the particle size D90 is detected to be less than 5 microns to be qualified, that is, a dispersible oil suspension is obtained.

[0056] The preparation methods of the emulsifiable concentrates, aqueous emulsions, microemulsions, aqueous suspensions, wettable powders and water dispersible granules involved in the comparative examples can be carried out by conventional methods, which will not be described in detail here.

[0057] The stabilizers in the examples and comparative examples are all anti-emamectin benzoate decomposition agents produced by Shenzhen Langtai Biotechnology Co., Ltd. D902.

[0058] Example 1: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0059] 3 parts of avermectin benzoate, 12 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0060] Example 2: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0061] 3 parts of avermectin benzoate, 12 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of alkylphenol polyoxyethylene ether phosphate, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0062] Example 3: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0063] 3 parts of avermectin benzoate, 12 parts of lufenuron, 5 parts of alkyl naphthalene sulfonate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0064] Example 4: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0065] 1 part of avermectin benzoate, 14 parts of lufenuron, 6 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 4 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0066] Example 5: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0067] 2 parts of avermectin benzoate, 13 parts of lufenuron, 6 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 7 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0068] Example 6: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0069] 4 parts of avermectin benzoate, 11 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 6 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil are made up to 100 parts.

[0070] Example 7: 10% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0071] 2 parts of avermectin benzoate, 8 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0072] Example 8: 25% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0073] 5 parts of avermectin benzoate, 20 parts of lufenuron, 8 parts of sulfosuccinate, 6 parts of polyethylene glycol fatty acid ester, 6 parts of fatty alcohol polyoxyethylene ether, 2 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0074] Comparative Example 1: 15% Emamectin Benzoate·Lufenuron EC

[0075] 3 parts of avermectin benzoate, 12 parts of lufenuron, 4 parts of dodecylbenzene sulfonate, 6 parts of nonylphenol polyoxyethylene ether, 3 parts of EO-PO block copolymer, 5 parts of cyclohexanone, 20 parts of methanol, 0.3 parts of stabilizer, and xylene is added to make up to 100 parts.

[0076] Comparative Example 2: 15% Emamectin Benzoate·Lufenuron Emulsion in Water

[0077] 3 parts of avermectin benzoate, 12 parts of lufenuron, 3 parts of castor oil polyoxyethylene ether, 3 parts of EO-PO block copolymer, 15 parts of xylene, 15 parts of cyclohexanone, 3 parts of ethylene glycol, 0.3 parts of stabilizer, and deionized water to make up to 100 parts.

[0078] Comparative Example 3: 15% Emamectin Benzoate·Lufenuron Microemulsion

[0079] 3 parts of avermectin benzoate, 12 parts of lufenuron, 3 parts of EO-PO block polyether, 7 parts of alkylphenol polyoxyethylene ether, 5 parts of cyclohexanone, 8 parts of methanol, 0.3 parts of stabilizer, and deionized water to make up to 100 parts.

[0080] Comparative Example 4: 15% Emamectin Benzoate·Lufenuron Aqueous Suspension

[0081] 3 parts of avermectin benzoate, 12 parts of lufenuron, 2 parts of polycarboxylate, 1 part of EO-PO block copolymer, 2 parts of naphthalenesulfonic acid formaldehyde condensate sodium salt, 1 part of alkyl phosphate, 5 parts of ethylene glycol, 0.2 parts of xanthan gum, 1 part of magnesium aluminum silicate, 0.2 parts of kason, 0.2 parts of defoamer, 0.3 parts of stabilizer, and make up to 100 parts with deionized water.

[0082] Comparative Example 5: 15% Emamectin Benzoate·Lufenuron Wettable Powder

[0083] 3 parts of emamectin benzoate, 12 parts of lufenuron, 4 parts of lignin sulfonate, 2 parts of fatty alcohol polyoxyethylene ether phosphate, 2 parts of phenethylphenol polyoxyethylene ether phosphate, 0.3 parts of stabilizer, and kaolin to make up to 100 parts.

[0084] Comparative Example 6: 15% Emamectin Benzoate·Lufenuron Water Dispersible Granules

[0085] 3 parts of avermectin benzoate, 12 parts of lufenuron, 4 parts of lignin sulfonate, 4 parts of polycarboxylate, 2 parts of phenethylphenol polyoxyethylene ether phosphate, 20 parts of corn starch, 0.3 parts of stabilizer, and ammonium sulfate is made up to 100 parts.

[0086] Comparative Example 7: 3% Emamectin Benzoate Dispersible Oil Suspension

[0087] 3 parts of emamectin benzoate, 3 parts of sulfosuccinate, 4 parts of polyethylene glycol fatty acid ester, 7 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 1.0 part of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil are made up to 100 parts.

[0088] Comparative Example 8: 12% Lufenuron dispersible oil suspension

[0089] 12 parts of lufenuron, 6 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 5 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and methyl peanut oil to make up to 100 parts.

[0090] Comparative Example 9: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0091] 3 parts of avermectin benzoate, 12 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of castor oil polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and vegetable soybean oil is made up to 100 parts.

[0092] Comparative Example 10: 15% Emamectin Benzoate·Lufenuron Dispersible Oil Suspension

[0093] 3 parts of avermectin benzoate, 12 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of sorbitan monostearate polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, 0.3 parts of stabilizer, and light mineral oil to make up to 100 parts.

[0094] Comparative Example 11: 25% Emamectin Benzoate·Lufenuron Aqueous Suspension

[0095] 5 parts of avermectin benzoate, 20 parts of lufenuron, 3 parts of polycarboxylate, 1 part of EO-PO block copolymer, 2 parts of naphthalenesulfonic acid formaldehyde condensate sodium salt, 1 part of alkyl phosphate, 5 parts of ethylene glycol, 0.2 parts of xanthan gum, 1 part of magnesium aluminum silicate, 0.2 parts of kason, 0.2 parts of defoamer, 0.3 parts of stabilizer, and make up to 100 parts with deionized water.

[0096] Comparative Example 12: Blank Control

[0097] 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, and methyl peanut oil to make up to 100 parts.

[0098] Test Example 1

[0099] The dispersible oil suspensions prepared in Examples 1-8 and Comparative Examples 7-10 were subjected to index detection and temperature durability test after preparation. The test results are shown in Table 1.

[0100] Table 1. Test results of various indicators of dispersible oil suspension samples of the present invention

[0101]

[0102] It can be seen from the results in Table 1 that the embodiments provided by the present invention have significantly better stability over time than the comparative examples by screening the dispersion medium and the auxiliary agent. Among them, the comparison between the embodiment 1 of the present invention and the embodiments 2 and 3 shows that the selection of sulfosuccinate and polyethylene glycol fatty acid ester can make the prepared dispersible oil suspension have better stability over time.

[0103] Test Example 2

[0104] The present invention is illustrated by the following specific field efficacy test.

[0105] The test formulations prepared in Examples 1-8 and Comparative Examples 1-12 were used for integrated control of cabbage pests (pieris rapae, beet armyworm and aphids), and their control efficacy was tested.

[0106] Test location: Agricultural vegetable base in Liucheng County, Liuzhou City, Guangxi Zhuang Autonomous Region

[0107] Select the area where cabbage pests and diseases are seriously ill, dilute the preparations made in Examples 1-8 and the preparations made in Comparative Examples 1-12 by 1200 times and spray evenly, and the application amount of the preparation is 12.5mL / mu. Spray the medicine once when the pests just appear in the early growth stage of cabbage, and spray until the leaves begin to drip. The area of ​​the test area is 5m*5m, and each treatment is repeated 3 times. The investigation is carried out 7 days after the application of the medicine. In each community, 100 cabbages are investigated, and the number of damaged cabbages is counted to investigate the effect of cabbage pest control. The investigation method refers to "GB / T17980 Pesticide Field Efficacy Test Guidelines (I)".

[0108] The pest control effect was calculated according to the following formula and the results are shown in Table 2.

[0109] Control effect (%) = (1-CK1×Pt1 / CK2×Pt2)×100.

[0110] Among them: CK1 represents the number of insects in the control area before treatment; Pt1 represents the number of insects in the treatment area after treatment; CK2 represents the number of insects in the control area after treatment; Pt2 represents the number of insects in the treatment area before treatment.

[0111] Table 2 Effects of Examples 1-8 and Comparative Examples 1-12 on the comprehensive control of cabbage pests

[0112]

[0113]

[0114] As can be seen from Table 2, the dispersible oil suspension of the present invention has excellent control effect on crop pests, and the dispersible oil suspension prepared by Example 1 has the best control effect on pests. At the same time, after comparing the embodiments and comparative examples in Table 2, it is found that the dispersible oil suspension of the present invention has better pest control effect than other formulations. Analysis shows that the methylated vegetable oil used in the dispersible oil suspension has the characteristics of being able to reduce the surface tension and contact angle of the liquid medicine, increase the amount of liquid medicine deposited on the leaf surface, and improve the interface transfer efficiency of the liquid medicine on the crop, that is, indirectly improve the pest control effect. And due to the safety and environmental protection characteristics of the methylated vegetable oil, the harm of harmful solvents polluting the environment when some pesticides are applied and the adverse effects on the health of users are avoided from the root. In addition, no adverse effects were found in the test agent on crops, and the agent was safe for natural enemy insects and aquatic organisms.

[0115] The preferred embodiments of the present invention are described in detail above, but the present invention is not limited thereto. Within the technical concept of the present invention, the technical solution of the present invention can be subjected to a variety of simple modifications, including the combination of various technical features in any other suitable manner, and these simple modifications and combinations should also be regarded as the contents disclosed by the present invention and belong to the protection scope of the present invention.

Claims

1. A dispersible oil suspension, characterized in that: The dispersible oil suspension contains emamectin benzoate and lufenuron as active ingredients, and also includes a dispersion medium, a dispersant, a wetting agent, an emulsifier, a thickener and a stabilizer; Wherein, the dispersion medium is methylated vegetable oil; the dispersant is sulfosuccinate and / or alkylnaphthalenesulfonate; the wetting agent is polyethylene glycol fatty acid ester and / or alkylphenol polyoxyethylene ether phosphate; and the emulsifier is fatty alcohol polyoxyethylene ether.

2. The dispersible oil suspension according to claim 1, wherein The methylated vegetable oil is selected from at least one of methylated peanut oil, methylated corn oil, methylated soybean oil and methylated palm oil, and is preferably methylated peanut oil.

3. The dispersible oil suspension according to claim 1 or 2, wherein The dispersant is sulfosuccinate, and the wetting agent is polyethylene glycol fatty acid ester; Preferably, the thickener is selected from at least one of organic bentonite, diatomaceous earth, attapulgite, fumed silica, polyvinyl pyrrolidone, methyl cellulose, polyvinyl alcohol, xanthan gum and magnesium aluminum silicate, preferably organic bentonite and fumed silica; Preferably, the stabilizer is an anti-emamectin benzoate decomposition agent produced by Shenzhen Langtai Biotechnology Co., Ltd. D902.

4. The dispersible oil suspension according to any one of claims 1 to 3, wherein The active ingredient accounts for 10-25% of the total weight of the dispersible oil suspension, preferably 15%; Preferably, the emamectin benzoate accounts for 1-5% of the total weight of the dispersible oil suspension, preferably 3%; Preferably, the lufenuron accounts for 8-20% by weight of the total weight of the dispersible oil suspension concentrate, preferably 12%.

5. The dispersible oil suspension according to any one of claims 1 to 4, wherein The dispersible oil suspension comprises the following components in parts by weight: 1-5 parts of emamectin benzoate, 8-20 parts of lufenuron, 52.2-69.7 parts of dispersion medium, 5-8 parts of dispersant, 5-6 parts of wetting agent, 4-8 parts of emulsifier, 2-2.5 parts of thickener and 0.3 parts of stabilizer; Preferably, the dispersible oil suspension comprises the following components in parts by weight: 3 parts of emamectin benzoate, 12 parts of lufenuron, 5 parts of sulfosuccinate, 5 parts of polyethylene glycol fatty acid ester, 8 parts of fatty alcohol polyoxyethylene ether, 1.5 parts of organic bentonite, 0.5 parts of fumed silica, and an anti-emamectin benzoate decomposition agent. D902 0.3 parts, methyl ester peanut oil is made up to 100 parts.

6. The dispersible oil suspension according to any one of claims 1 to 5, wherein The microparticle size D90 of the dispersible oil suspension is less than 5 microns.

7. A method for preparing a dispersible oil suspension according to any one of claims 1 to 6, characterized in that: The method comprises the following steps: (1) mixing a dispersion medium, a dispersant, a wetting agent and an emulsifier to obtain a mixed solution; (2) adding emamectin benzoate, lufenuron, a thickener and a stabilizer to the mixed solution obtained in step (1), and obtaining a dispersion by shearing; (3) sand-milling the dispersion obtained in step (2) to obtain the dispersible oil suspension.

8. The method according to claim 7, wherein: In step (1), the mixed solution is obtained by stirring at a speed of 60 r / min for 10-15 min; Preferably, the shearing speed in step (2) is 3000-3500 r / min, and the time is 10-20 min; Preferably, the discharge flow rate of the sand mill in step (3) is 360 kg / h, and the material temperature in the grinding chamber of the sand mill is below 35°C.

9. Use of the dispersible oil suspension concentrate according to any one of claims 1 to 6 or the dispersible oil suspension concentrate obtained by the preparation method according to claim 7 or 8 in controlling lepidoptera, homoptera, diptera and thrips pests in crops; Preferably, the insect pest is selected from at least one of stem borers, cotton bollworms, cotton aphids, beet armyworms, Spodoptera litura, cabbage loopers, leaf miners, red spiders, rust mites, whiteflies and thrips.

10. The use according to claim 9, wherein: The dispersible oil suspension is diluted with water and then sprayed for application, wherein the concentration after dilution is 0.66-0.93 mL / kg water, preferably 0.83 mL / kg water; Preferably, the dosage of the preparation is 10-14 mL / mu, preferably 12.5 mL / mu.

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