Magnetically-driven biopsy needle type biopsy sampling capsule

Abstract

The invention provides a magnetic drive biopsy needle type biopsy sampling capsule which comprises a capsule shell and a micro camera fixed in the capsule shell, the micro camera is connected with a micro camera data line, the micro camera data line is led out from the interior of the capsule shell, and after sampling is completed, the micro camera data line is connected with the capsule shell. The miniature camera data line serves as a traction rope, and the magnetic drive biopsy needle type biopsy sampling capsule is taken out of the oral cavity through the miniature camera data line. The magnetic drive biopsy needle type biopsy sampling capsule has the advantages that the miniature camera data line led out from the tail of the magnetic drive biopsy needle type biopsy sampling capsule can serve as a pull line and is directly pulled out from the mouth, and therefore the time needed by sampling is greatly shortened.

Description

Technical Field

[0001] The invention relates to a capsule endoscope, in particular to a magnetically driven biopsy needle type biopsy sampling capsule. Background Art

[0002] Capsule endoscope (CE) is a swallowable medical device used to examine the human gastrointestinal tract. It is usually equipped with one or two micro cameras to capture images of the gastrointestinal tract. Doctors can then assess health conditions by examining these images. On this basis, the new magnetically driven biopsy capsule has the functions of biopsy and active movement. It can actively move under the drive of an external magnetic field and cooperate with the micro camera to reach the lesion site to complete the biopsy.

[0003] Existing magnetically driven biopsy capsules are all wireless capsule endoscopes. After completing the biopsy task in the human gastrointestinal tract, the sampling results can only be obtained after the capsule is excreted from the body through intestinal peristalsis. This causes the sampling cycle of the biopsy capsule to be affected by the patient's digestive cycle, which is not conducive to obtaining biopsy results in a timely manner. Summary of the invention

[0004] In order to overcome the problem that the current magnetically driven biopsy capsule has a long sampling cycle and a small single sampling volume, which makes it inconvenient to obtain effective sampling results in a timely manner, the present invention provides a magnetically driven biopsy needle biopsy sampling capsule. The micro camera data cable led out at the tail of the magnetically driven biopsy needle biopsy sampling capsule can be used as a traction line and directly pulled out from the mouth, thereby greatly reducing the time required for sampling. The magnetically driven biopsy needle biopsy sampling capsule can be taken out immediately after the sampling is completed, so it will not be affected by the patient's digestive cycle. Compared with the traditional wireless magnetically driven biopsy capsule, it is more convenient.

[0005] The present invention provides a magnetically driven biopsy needle biopsy sampling capsule, comprising a capsule shell and a micro camera fixed inside the capsule shell, wherein the micro camera is connected to a micro camera data cable, and the micro camera data cable is led out from the inside of the capsule shell. After sampling is completed, the micro camera data cable is used as a traction rope to remove the magnetically driven biopsy needle biopsy sampling capsule from the oral cavity through the micro camera data cable.

[0006] As a further improvement of the present invention, a mounting groove is provided at the front end of the capsule shell, and the micro camera is fixed in the mounting groove.

[0007] As a further improvement of the present invention, the micro camera data line is led out from the rear end of the capsule shell.

[0008] As a further improvement of the present invention, a jacket is provided inside the installation groove, and the miniature camera is wrapped by the jacket.

[0009] As a further improvement of the present invention, the outer sleeve is a tubular silicone sleeve, and the silicone sleeve and the miniature camera are interference fit.

[0010] As a further improvement of the present invention, a sampling assembly is provided inside the capsule shell, and the sampling assembly includes a magnet, a biopsy needle base, a biopsy needle and a spring. The magnet is slidably matched with the capsule shell, the biopsy needle base is fixed on the magnet, and the biopsy needle is fixed on the biopsy needle base. Under the action of an external electromagnetic drive system, the magnet can drive the biopsy needle to pop out for sampling. The spring is clamped between the capsule shell and the biopsy needle base, and the spring can achieve the resetting of the biopsy needle.

[0011] As a further improvement of the present invention, there are at least two biopsy needles.

[0012] As a further improvement of the present invention, each biopsy needle corresponds to a coaxially mounted spring.

[0013] As a further improvement of the present invention, there are two biopsy needles which are symmetrically arranged on both sides of the miniature camera.

[0014] As a further improvement of the present invention, the capsule shell is composed of two left and right shells, and the biopsy needle and the biopsy needle base are assembled in a detachable manner.

[0015] The beneficial effects of the present invention are:

[0016] 1. The micro camera data line led out from the tail of the magnetically driven biopsy needle biopsy sampling capsule can be used as a traction line and directly pulled out from the mouth, thereby greatly reducing the time required for sampling.

[0017] 2. The magnetically driven biopsy needle biopsy sampling capsule has high functional integration, low manufacturing cost and simple control and operation.

[0018] 3. The system is easy to use and highly safe. Even if the external magnetic control system fails, the capsule can be directly pulled out without any safety concerns.

[0019] 4. Provide fault tolerance for sampling biopsy. If the capsule fails to successfully obtain the sample after being taken out of the human body, the sampling process can be repeated in a short time due to the short cycle, saving time and cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other solutions can be obtained based on these drawings without paying creative work.

[0021] Figure 1 It is a schematic diagram of the internal structure of a magnetically driven biopsy needle biopsy sampling capsule in an example of the present invention.

[0022] Figure 2 It is a schematic diagram of the three-dimensional structure of a magnetically driven biopsy needle biopsy sampling capsule in an example of the present invention.

[0023] Figure 3 Schematic diagram of a magnetically driven biopsy needle biopsy sampling capsule reaching a target position under the action of an external magnetic control system in an example of the present invention

[0024] Figure 4 It is a schematic diagram of a magnetically driven biopsy needle biopsy sampling capsule starting sampling in an example of the present invention.

[0025] Figure 5 It is a schematic diagram of a magnetically driven biopsy needle biopsy sampling capsule being pulled out after completing sampling in an example of the present invention. DETAILED DESCRIPTION

[0026] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments may be combined with each other.

[0027] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present invention. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0028] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0029] The present invention will be further described below in conjunction with the accompanying drawings and specific implementation methods.

[0030] like Figures 1 to 5 As shown, a magnetically driven biopsy needle biopsy sampling capsule includes a capsule shell 1 and a micro camera 3 fixed inside the capsule shell 1, the micro camera 3 is connected to a micro camera data cable 8, and the micro camera data cable 8 is led out from the inside of the capsule shell 1. When the sampling is completed, the micro camera data cable 8 is used as a traction rope to take the magnetically driven biopsy needle biopsy sampling capsule out of the oral cavity through the micro camera data cable 8.

[0031] The micro camera data line 8 is led out from the tail of the capsule and connected to the outside world through the human mouth. On the one hand, it can be used to transmit camera data, and on the other hand, it can be used as a traction rope to remove the magnetically driven biopsy needle biopsy sampling capsule from the oral cavity.

[0032] After the magnetically driven biopsy needle biopsy sampling capsule completes the sampling task, the micro camera data line 8 extending from the tail of the magnetically driven biopsy needle biopsy sampling capsule is pulled, and the capsule is taken out of the patient's mouth to quickly obtain the sampling result.

[0033] The front end of the capsule shell 1 is provided with a mounting groove, and the micro camera 3 is fixed in the mounting groove.

[0034] The micro camera data line 8 is led out from the rear end of the capsule shell 1 .

[0035] A cover 7 is provided in the installation groove, and the micro camera 3 is wrapped by the cover 7 .

[0036] The outer sleeve 7 is preferably a tubular silicone sleeve, and the silicone sleeve and the micro camera 3 are interference fit, and the installation groove is a cylindrical groove that matches the silicone sleeve.

[0037] The outer sleeve 7 is made of a material with a relatively large friction coefficient.

[0038] The outer sleeve 7 is pressed and embedded in the installation groove. Under the tight fit of the capsule shell 1, the outer sleeve 7 is pressed to provide friction force to the micro camera 3 to prevent the micro camera 3 from axial slippage.

[0039] A sampling component is disposed inside the capsule shell 1 .

[0040] The sampling assembly includes a magnet 2, a biopsy needle base 4, a biopsy needle 6 and a spring 5. The magnet 2 is slidably matched with the capsule shell 1. The magnet 2 can slide back and forth along the axial direction of the capsule shell 1. The biopsy needle base 4 is fixed on the magnet 2. The biopsy needle 6 is fixed on the biopsy needle base 4. The biopsy needle 6 can move with the magnet 2. The movement of the biopsy needle 6 is controlled by driving the magnet 2 to move.

[0041] The magnet 2 can drive the biopsy needle 6 to pop out for sampling under the action of the external electromagnetic drive system. After the sampling is completed, the biopsy needle 6 is reset under the elastic force of the spring 5.

[0042] The spring 5 is clamped between the capsule shell 1 and the biopsy needle base 4. After the sampling is completed, the spring 5 can realize the reset of the biopsy needle 6 and the magnet 2.

[0043] The magnetically driven biopsy needle biopsy sampling capsule controls the resetting of the biopsy needle 6 by the spring 5, has a fast response, and can provide elastic force to prevent the biopsy needle 6 from popping out and causing damage to the human body when the capsule moves.

[0044] There are at least two biopsy needles 6, preferably two, three, four, or even more. The magnetically driven biopsy needle biopsy sampling capsule has at least two biopsy needles 6, which can increase the sampling volume of a single sampling and ensure a higher success rate of sampling.

[0045] Each biopsy needle 6 corresponds to a coaxially mounted spring 5 .

[0046] The biopsy needles 6 are preferably two and symmetrically arranged on both sides of the miniature camera 3. The magnetically driven biopsy needle biopsy sampling capsule has two biopsy needles 6, which can increase the sampling volume of a single sampling and ensure a higher success rate of sampling.

[0047] The capsule shell 1 is composed of two left and right shells, which are bonded by glue and are easy to assemble.

[0048] The shape of the capsule shell 1 of the magnetically driven biopsy needle biopsy sampling capsule can be cylindrical, rhombus-shaped or olive-shaped.

[0049] The biopsy needle 6 and the biopsy needle base 4 are assembled in a detachable manner, and sampling needles 6 of different models can be quickly replaced.

[0050] The magnet 2 inside the capsule shell 1 may be one or more.

[0051] After the magnetically driven biopsy needle biopsy sampling capsule is swallowed into the human body, the patient is placed on the magnetically controlled platform, and the external electromagnetic driving system can drive the magnetically driven biopsy needle biopsy sampling capsule to the lesion location in the gastrointestinal tract.

[0052] The magnetically driven biopsy needle biopsy sampling capsule moves under the action of the external electromagnetic drive system. It reaches the designated sampling position under the visual guidance of the micro camera. Figure 3 It is a schematic diagram before sampling in one example of the present invention.

[0053] After the magnetically driven biopsy needle biopsy sampling capsule reaches the position, under the action of the external electromagnetic driving system, the sampling needle 6 inside the magnetically driven biopsy needle biopsy sampling capsule pops out to perform sampling. Figure 4 It is a sampling schematic diagram in an example of the present invention.

[0054] After completing the sampling task, the external electromagnetic drive system applies a weak magnetic field, the biopsy needle 6 is retracted under the action of the internal spring 5, and the magnetically driven biopsy needle biopsy sampling capsule is pulled by the micro camera data cable 8 connected to the outside world and taken out from the esophagus. Figure 5 It is a schematic diagram of completing sampling in an example of the present invention.

[0055] The magnetically driven biopsy needle biopsy sampling capsule provided by the present invention can be taken out immediately after the sampling is completed, so it will not be affected by the patient's digestive cycle, and is more convenient than the original wireless magnetically driven biopsy capsule. The magnetically driven biopsy needle biopsy sampling capsule integrates the visual system (micro camera 3), the sampling system (biopsy needle 6) and the driving system (magnet 2), and uses the micro camera data line 6 as a traction line. After the capsule moves to the lesion area for sampling, the sampling capsule is immediately taken out through the mouth through the traction line.

[0056] The magnetically driven biopsy needle biopsy sampling capsule provided by the present invention has the following characteristics:

[0057] 1. The magnetically driven biopsy needle biopsy sampling capsule has two biopsy needles 6, which can perform two samples at the same time to increase the sampling volume of a single sample.

[0058] 2. The micro camera data line 8 is used as a traction line. After the capsule moves to the lesion area for sampling, the sampling capsule is immediately taken out through the mouth through the traction line. It can be taken out directly after the sampling activity is completed, which reduces the time required for biopsy sampling. Compared with the wireless magnetically driven capsule sampling method used in the prior art, this method has higher sampling efficiency and lower time cost.

[0059] 3. The capsule integrates magnetic drive motion, visual servoing, sampling and other functions, making the capsule more comprehensive and the manufacturing cost lower.

[0060] 4. Based on the capsule used in the prior art, the capsule increases the number of biopsy needles 6, increases the single collection volume, and greatly improves the sampling success rate and sample reliability.

[0061] 5. The capsule has a simple structure and the shell is manufactured in an integrated manner, which reduces processing time and economic costs and is easy to assemble.

[0062] The above contents are further detailed descriptions of the present invention in combination with specific preferred embodiments, and it cannot be determined that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. A magnetically driven biopsy needle biopsy sampling capsule, characterized in that: It includes a capsule shell and a micro camera fixed inside the capsule shell, the micro camera is connected to a micro camera data cable, and the micro camera data cable is led out from the inside of the capsule shell. When the sampling is completed, the micro camera data cable is used as a traction rope to take the magnetically driven biopsy needle biopsy sampling capsule out of the oral cavity through the micro camera data cable.

2. The magnetically driven biopsy needle biopsy sampling capsule according to claim 1, characterized in that: The front end of the capsule shell is provided with a mounting groove, and the micro camera is fixed in the mounting groove.

3. The magnetically driven biopsy needle biopsy sampling capsule according to claim 2, characterized in that: The micro camera data line is led out from the rear end of the capsule shell.

4. The magnetically driven biopsy needle biopsy sampling capsule according to claim 2, characterized in that: A jacket is arranged inside the installation groove, and the miniature camera is wrapped by the jacket.

5. The magnetically driven biopsy needle biopsy sampling capsule according to claim 4, characterized in that: The outer sleeve is a tubular silicone sleeve, and the silicone sleeve and the miniature camera are interference-fitted.

6. The magnetically driven biopsy needle biopsy sampling capsule according to claim 1, characterized in that: A sampling assembly is provided inside the capsule shell, and the sampling assembly includes a magnet, a biopsy needle base, a biopsy needle and a spring. The magnet is slidably matched with the capsule shell, the biopsy needle base is fixed on the magnet, and the biopsy needle is fixed on the biopsy needle base. Under the action of an external electromagnetic drive system, the magnet can drive the biopsy needle to pop out for sampling. The spring is clamped between the capsule shell and the biopsy needle base, and the spring can achieve the resetting of the biopsy needle.

7. The magnetically driven biopsy needle biopsy sampling capsule according to claim 6, characterized in that: There are at least two biopsy needles.

8. The magnetically driven biopsy needle biopsy sampling capsule according to claim 7, characterized in that: Each biopsy needle corresponds to a coaxially mounted spring.

9. The magnetically driven biopsy needle biopsy sampling capsule according to claim 7, characterized in that: There are two biopsy needles which are symmetrically arranged on both sides of the miniature camera.

10. The magnetically driven biopsy needle biopsy sampling capsule according to claim 6, characterized in that: The capsule shell is composed of two left and right shells, and the biopsy needle and the biopsy needle base are assembled in a detachable manner.

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