Additive for brightening skin color and fading color spots and application thereof

Abstract

The invention discloses an additive for brightening skin color and fading color spots. The active ingredients of the additive comprise diglucosyl gallic acid, aminoethyl hypophosphorous acid, hydrolyzed conchiolin protein, pearl powder, glabridin, rhizoma atractylodis macrocephalae root extract and nonapeptide-1. According to the additive for brightening the skin color and lightening the color spots, multiple active ingredients are strongly combined, the multi-azimuth long-acting whitening effect is achieved, the color spots can be effectively lightened, the skin color can be brightened, the excellent anti-oxidation characteristic is achieved, the skin elasticity can be enhanced, and pigmentation caused by ultraviolet irradiation is reduced. The additive for brightening skin color and fading color spots is dry powder, has good stability, is easy to store and transport, and can be added into various skin care products as required.

Description

Technical Field

[0001] The invention relates to the field of cosmetics, and in particular to an additive for brightening skin tone and fading spots and an application thereof. Background Art

[0002] Pigment spots are a common skin disease caused by the increase and deposition of melanin. There are many reasons for the occurrence of pigment spots, the most common of which are melanin deposition caused by sun exposure, metal poisoning caused by the use of inferior cosmetics, pigment deposition caused by trauma, and melanin metabolism disorders caused by irregular lifestyles. Currently, whitening cosmetics are commonly used to remove pigment spots. Although they can whiten the skin in a short period of time, once they are discontinued, the skin will immediately become darker and wrinkles will deepen. The reason is that whitening cosmetics often contain a large amount of lead, mercury and other metal substances that are toxic to the skin and even the nervous system. These metal substances can act on the enzymes in melanin production and inactivate them, thereby preventing the formation of pigment spots. However, this effect is short-lived. After discontinuation, the enzymes will continue to work and produce melanin, and toxic metal substances will also pose a threat to human health.

[0003] There are many skin care products on the market that can lighten spots and delay skin aging, but many of these products have problems such as ineffective effects, the effects are prone to recurrence once discontinued, and they are easily oxidized and denatured due to their nature, and large doses of active ingredients are required for quick effects, but large doses can easily lead to skin intolerance. Therefore, skin care products with high safety, good spot-lightening effects, and the ability to delay skin aging have great development value and have always been a hot topic in the field of skin care research. Summary of the invention

[0004] The object of the present invention is to overcome at least one shortcoming of the prior art and to provide an additive for brightening skin color and fading spots and its application.

[0005] The technical solution adopted by the present invention is: In a first aspect, the present invention provides an additive for brightening skin tone and fading spots, which includes diglucosyl gallic acid, aminoethyl hypophosphite, hydrolyzed conchiolin, pearl powder, glabridin, Atractylodes macrocephala root extract, and nonapeptide-1.

[0006] In some examples, the mass ratio of the additives is: 8 to 12 parts of diglucosyl gallic acid, 78 to 82 parts of aminoethyl hypophosphite, 1.5 to 2.5 parts of hydrolyzed conchiolin, 1.5 to 2.5 parts of pearl powder, 0.5 to 1.5 parts of glabridin, 2.5 to 3.5 parts of Atractylodes macrocephala root extract, and 1.5 to 2.5 parts of nonapeptide-1.

[0007] In some examples, the mass ratio of the additives is: 10 parts of diglucosyl gallic acid, 80 parts of aminoethyl hypophosphite, 2 parts of hydrolyzed conchiolin, 2 parts of pearl powder, 1 part of glabridin, 3 parts of Atractylodes macrocephala root extract, and 2 parts of nonapeptide-1.

[0008] In some examples, the additive is a dry powder.

[0009] In a second aspect, a skin care product for brightening skin tone and fading spots comprises auxiliary materials and functional ingredients, wherein the functional ingredients are the additive for brightening skin tone and fading spots as described in the first aspect of the present invention.

[0010] In some examples, the additive for brightening skin tone and lightening spots is added in a skin care product in an amount of 0.2 to 1.0% by weight.

[0011] In some examples, the skin care product is a cream, lotion, water solution, essence, gel, or mask.

[0012] In some examples, the excipients include solvents, humectants, emulsifiers, chelating agents, and preservatives.

[0013] In some examples, the moisturizer is selected from one or more of butylene glycol, glycerin, inositol, acetyl glucosamine, sodium hyaluronate, and sea buckthorn extract.

[0014] In some examples, the emulsifier is selected from one or more of glyceryl stearate, PEG-100 stearate, cetearyl alcohol, cetearyl alcohol, and cetearyl glucoside.

[0015] The beneficial effects of the present invention are: The powerful combination of multiple active ingredients in the additive for brightening skin tone and fading pigmentation of the present invention achieves a multi-faceted and long-lasting whitening effect. It can not only effectively fade pigmentation and brighten skin tone, but also has excellent antioxidant properties, can enhance skin elasticity, and reduce pigmentation caused by ultraviolet radiation.

[0016] The additive for brightening skin color and fading spots of the present invention is in the form of dry powder, has good stability, is easy to store and transport, and can be added to various skin care products as needed. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 The effect comparison of Example 1 before and after 4 weeks of use is shown.

[0018] Figure 2 The results of Example 2 are compared before and after 4 weeks of use. DETAILED DESCRIPTION

[0019] The following disclosure provides many different embodiments or examples for implementing different solutions of the present invention.

[0020] Aminoethylphosphinic acid is a commonly used whitening agent. Its mechanism of action is different from arbutin, kojic acid, etc. It inhibits the activity of tyrosinase to reduce the production of melanin. It can stabilize dopachrome and inhibit the activity of dopachrome isomerase, preventing the natural polymerization of dopachrome, thereby effectively controlling the production of melanin, while improving skin microcirculation, activating metabolism, and making the skin appear brighter.

[0021] Nacon diglucosyl gallic acid solution, its core ingredient is diglucosyl gallic acid, its English name is DIGLUCOSYL GALLIC ACID, it also has the nicknames of seven-fold white and seven-fold bright. There is a natural microbial layer on our skin, which is a general term for microorganisms existing on the surface of the skin and part of the stratum corneum, which plays an important role in maintaining skin health and defense.

[0022] Hydrolyzed Conchiolin Protein (HCP) is a hydrolyzate extracted from the hard protein of shellfish (such as pearls, oysters, etc.) and is an endothelin antagonist. In the cosmetics industry, hydrolyzed conchiolin is mainly used as a nutritional adjuvant. It has moisturizing and emollient effects, can promote the skin's absorption of other active ingredients, and enhance antioxidant and anti-aging effects. In addition, it has anti-inflammatory properties and can inhibit skin allergic reactions caused by histamine. The efficacy of hydrolyzed conchiolin in whitening has also been studied. Studies have shown that it can inhibit the activity of tyrosinase and reduce the production of melanin, thereby achieving a whitening effect.

[0023] Pearl powder is rich in various amino acids, trace elements, polysaccharides and other ingredients, which can penetrate deep into the skin, promote skin metabolism, prevent melanin precipitation, and thus achieve the effect of whitening and removing spots.

[0024] Glycyrrhizin is a flavonoid extracted from a precious plant called Glycyrrhiza glabra. Glycyrrhizin is known as "whitening gold" for its powerful whitening effect. It can eliminate free radicals and melanin at the bottom of the skin, and is a holy thing for skin whitening and anti-aging.

[0025] Atractylodes macrocephala root extract quickly and visibly lightens and evens skin tone. It goes beyond common whitening skincare ingredients to effectively maintain epidermal homeostasis, prevent inflammatory pigmentation, and fight urban photoaging.

[0026] Nonapeptide-1 is a small molecule whitening biomimetic peptide composed of nine amino acid molecules. It is an α-MSH antagonist that acts on the skin with high specificity. Nonapeptide-1 is a hostile force to melanin and can compete with various factor signals to bind to receptors on melanocytes to inhibit the activation of tyrosinase by melanocytes, thereby reducing the production of melanin.

[0027] The compositions of the embodiments and comparative examples of the present invention are shown in Table 1. The components are mixed according to the proportions in Table 1 to obtain the additive for brightening skin tone and fading spots.

[0028] Table 1. Mass fraction composition of additives in different examples Mass content Diglucosylgallic acid Aminoethyl hypophosphite Hydrolyzed Conchiolin Pearl powder Glabridin Atractylodes macrocephala root extract Nonapeptide-1 Example 1 8 82 1.5 2.5 0.8 3.4 1.8 Example 2 10 80 2 2 1 3 2 Example 3 12 78 2.5 1.5 1.1 2.8 2.1 Comparative Example 1 0 80 2 2 1 3 2 Comparative Example 2 10 0 2 2 1 3 2 Comparative Example 3 10 80 0 2 1 3 2 Comparative Example 4 10 80 2 0 1 3 2 Comparative Example 5 10 80 2 2 0 3 2 Comparative Example 6 10 80 2 2 1 0 2 Comparative Example 7 10 80 2 2 1 3 0 Comparative experiment on skin lightening effect 1) Subjects: 90 subjects were selected, with random gender, age of 20-45 years old, and the melanin content of the inner side of the curved arm was between 160 and 250. The subjects had no serious systemic diseases, no immunodeficiency or autoimmune diseases, no active allergic diseases, no history of allergies to skin care cosmetics, and no systemic use of hormone drugs and immunosuppressants within 1 month. The subjects were randomly divided into 18 groups, 5 people in each group. The additive for brightening skin and fading spots prepared by the above-mentioned embodiment and comparative example composition was diluted with water to a 0.1 wt% aqueous solution, and an appropriate amount of preservatives was added to the aqueous solution to conduct a comparison experiment on the effect of brightening skin.

[0029] 2) Test indicators: Skin whiteness (L* value), L value is white balance, the larger the value is, the more the color tends to be white, and vice versa; Skin brightness (ITA value), ITA value is the skin individual type angle, which is a numerical value related to L value and b value that characterizes skin brightness. The larger the ITA° value is, the brighter the skin is, and vice versa, the darker the skin is.

[0030] 3) Test method: Select a test area and a blank area (without any sample) with the same skin area on the test subject, apply the test sample to the test area once in the morning and evening every day, and the amount of application depends on personal usage habits. After using the test product for 8 weeks, use the German CK company's multifunctional skin test system CM825 and skin color difference test probe CL400 to collect data on the test area.

[0031] Comparison of the effects of Example 1 and 2 before and after 4 weeks of use Figure 1 , 2 The specific test results after 8 weeks of use are shown in the following table, where: Formula 1: △L * Value = L * Value (test area) - L * value(blank area); Formula 2: △ITA 0 Value = ITA 0 Value (test area) - ITA 0 value (blank area).

[0032] The results of skin whiteness (L* value) measurement are shown in Table 2.

[0033] Table 2 Skin whiteness (L* value) measurement results Sample set L* value (test area) L* value (blank area) △L* value Example 1 72.34 63.25 9.09 Example 2 73.58 59.86 13.72 Example 3 71.28 60.45 10.83 Comparative Example 1 61.16 60.24 0.92 Comparative Example 2 62.79 60.53 2.26 Comparative Example 3 63.75 62.06 1.69 Comparative Example 4 64.84 61.81 3.03 Comparative Example 5 66.75 62.52 4.23 Comparative Example 6 66.01 60.84 5.17 Comparative Example 7 66.88 62.95 3.93 The results of skin brightness (ITA value) measurement are shown in Table 3.

[0034] Table 3 Skin brightness (ITA value) Measurement results Sample set <![CDATA[ITA 0 Value (test area)]]> <![CDATA[ITA 0 Value (blank space)]]> <![CDATA[△ITA 0 Value]]> Example 1 46.17 29.65 16.52 Example 2 46.23 32.58 13.65 Example 3 46.25 29.44 16.81 Comparative Example 1 34.65 31.27 3.38 Comparative Example 2 35.84 32.14 3.7 Comparative Example 3 34.05 28.85 5.2 Comparative Example 4 33.22 29.92 3.3 Comparative Example 5 40.18 31.88 8.3 Comparative Example 6 42.88 33.16 9.72 Comparative Example 7 36.27 28.25 8.02 It can be seen from Table 2 and Table 3 that after the subjects used the additive for brightening skin color and fading spots prepared in the embodiment of the present invention, the L* value and ITA value of the test area of ​​the subjects were O The values ​​increased significantly, and there were significant differences compared with the control group (P<0.05), and there was a clear synergistic effect.

[0035] The above is a further detailed description of the present invention, which should not be regarded as a limitation on the specific implementation of the present invention. For ordinary technicians in the technical field to which the present invention belongs, simple deduction or replacement without departing from the concept of the present invention is within the protection scope of the present invention.

Claims

1. An additive for brightening skin tone and fading spots, characterized in that: The invention comprises diglucosyl gallic acid, aminoethyl hypophosphite, hydrolyzed conchiolin, pearl powder, glabridin, Atractylodes macrocephala root extract and nonapeptide-1.

2. The additive according to claim 1, characterized in that The mass ratio is: 8-12 parts of diglucosyl gallic acid, 78-82 parts of aminoethyl hypophosphite, 1.5-2.5 parts of hydrolyzed conchiolin, 1.5-2.5 parts of pearl powder, 0.5-1.5 parts of glabridin, 2.5-3.5 parts of Atractylodes macrocephala root extract, and 1.5-2.5 parts of nonapeptide-1.

3. The additive according to claim 2, characterized in that The mass ratio is: 10 parts of diglucosyl gallic acid, 80 parts of aminoethyl hypophosphite, 2 parts of hydrolyzed conchiolin, 2 parts of pearl powder, 1 part of glabridin, 3 parts of Atractylodes macrocephala root extract, and 2 parts of nonapeptide-1.

4. The additive according to any one of claims 1 to 3, characterized in that The additive is in the form of dry powder.

5. A skin care product for brightening skin tone and fading spots, comprising auxiliary materials and functional ingredients, characterized in that: The functional ingredient is the additive for brightening skin color and lightening spots as described in any one of claims 1 to 4.

6. The skin care product according to claim 5, characterized in that The additive for brightening skin tone and fading spots is added in a skin care product in an amount of 0.2 to 1.0% by weight.

7. The skin care product according to claim 5, characterized in that: The skin care products are creams, lotions, water solutions, essences, gels, and facial masks.

8. The skin care product according to claim 5, characterized in that The auxiliary materials include solvents, moisturizers, emulsifiers, chelating agents and preservatives.

9. The skin care product according to claim 8, characterized in that: The moisturizing agent is selected from one or more of butylene glycol, glycerin, inositol, acetyl glucosamine, sodium hyaluronate and sea buckthorn extract.

10. The skin care product according to claim 8, characterized in that: The emulsifier is selected from one or more of glyceryl stearate, PEG-100 stearate, cetearyl alcohol, cetearyl alcohol, and cetearyl glucoside.

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