Plant essential oil-based hoof bath emulsion composition and preparation method thereof

Through the plant essential oil-based hoof bath lotion composition, the problems of heavy metal pollution and drug resistance in traditional hoof baths are solved, and an environmentally friendly and harmless prevention and treatment plan is provided, which effectively kills pathogenic bacteria and reduces animal hoofs. Sick limp rate.

CN119214947APending Publication Date: 2024-12-31BEIJING JIANYOU HUIZHONG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411457317.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-18
Publication Date
2024-12-31

AI Technical Summary

Technical Problem

Among the traditional hoof bath products on the market, formalin causes harm to the respiratory tract and skin of humans and animals. Copper sulfate and chelated zinc lead to chemical pollution and environmental risks of heavy metals, and antibiotic use leads to drug resistance.

Method used

Provided is a plant essential oil-based hoof bath emulsion composition, which comprises 10% to 23% of plant essential oil, 10% to 23% of ethanol, 1% to 5% of dextrin mixture, 4% to 15% of emulsifier, 40% to 75% of water %, the plant essential oil is a combination of thymeol or thymeol, carvacrol and cinnamaldehyde, and is prepared by stirring and dissolving steps to form a liquid product that is easily dissolved.

Benefits of technology

This lotion effectively kills pathogenic bacteria related to horn disease, does not contain heavy metals, is environmentally friendly, has no irritating odor, is harmless to humans and animals, and has better preventive and therapeutic effects. It is suitable for the prevention and treatment of animal horn disease.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a plant essential oil-based hoof bath emulsion composition and a preparation method thereof, and belongs to the field of veterinary bacteriostasis and disinfection. The plant essential oil-based hoof bath emulsion composition comprises the following components in percentage by mass: 10%-23% of plant essential oil, 10%-23% of ethanol, 1%-5% of a dextrin mixture, 4%-15% of an emulsifier and 40%-75% of water, the plant essential oil is thymol or is formed by compounding thymol with one or two of carvacrol and cinnamyl aldehyde. The plant essential oil-based hoof bath emulsion composition can effectively kill hoof disease-related pathogenic bacteria, does not contain heavy metals, and is environment-friendly; no pungent smell, no corrosion, and no harm to human and animals; the solution is liquid, is easy to dilute uniformly and is convenient to operate; compared with formalin, the composition has better prevention and treatment effects on animal hoof diseases.
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Description

Technical Field

[0001] The invention relates to a plant essential oil-based hoof bath emulsion composition and a preparation method thereof, and belongs to the field of veterinary antibacterial disinfection. Background Art

[0002] Hoof diseases mainly include hoof warts, interdigital dermatitis, foot rot, and interdigital skin hyperplasia. It is a common surgical disease in animals, with the highest incidence in horses and cattle. It can cause draft animals to lose their labor force and significantly reduce milk production in dairy animals.

[0003] In order to effectively prevent and control hoof diseases, ranches often use hoof baths for prevention and treatment. The main principle is to kill the pathogens of hoof diseases, such as Treponema, Fusobacterium necroticum, and Bacillus tuberculosis, and to prevent and treat hoof diseases by curbing the source.

[0004] At present, traditional hoof baths on the market mainly include formalin (formaldehyde solution), copper sulfate, antibiotics and Chinese medicinal materials. For example, Chinese patent CN116115707A discloses a concentrated foam bath for preventing and treating cow hoof rot, which is made of the following components by mass fraction: 1-8% polyhexamethylene biguanide hydrochloride, 1-2% o-phthalaldehyde, 12-20% Chinese medicinal extract, 5-10% cooling agent, 5-10% foaming agent, 1-3% foam stabilizer. %, antifreeze 10-15%, pigment 1-3%, pH regulator 0.1-0.3%, the balance is purified water; Chinese patent CN118178530A discloses an ointment for treating cow foot rot, the ointment raw materials are as follows: matrine 2-10 parts by weight, total flavonoids of wolfsbane 8-20 parts by weight, zeuraminol 5-15 parts by weight, copper 1-5 parts by weight, chelated zinc 1-5 parts by weight, glycerol 0.5-3 parts by weight, Tween 80 0.5-3 weight parts, 2-5 weight parts of ichthyol, the copper is copper sulfate, and the chelated zinc is amino acid chelated zinc; although it has a good inhibitory effect on necrotic Fusobacterium and nodular Bacteroides, and has a good therapeutic effect on the treatment of cow foot rot; but there are many problems in the use process; for example, although formalin is cheap and effective, it requires an environment above 13°C and has a strong odor, which is harmful to the respiratory tract and skin of humans and animals; although chemical reagents such as copper sulfate and chelated zinc have good effects and little irritation, they can cause serious chemical pollutants such as heavy metals, are easy to be accidentally ingested and poisoned, and have environmental risks; the use of antibiotics to prevent and treat hoof diseases is very popular at home and abroad, but excessive use can lead to the development of drug resistance. Summary of the invention

[0005] [Technical issues]

[0006] Traditional hoof baths on the market mainly include formalin (formaldehyde solution), copper sulfate, antibiotics and Chinese medicinal materials. Formalin (formaldehyde solution) often causes damage to the respiratory tract and skin of humans and animals. Although chemical reagents such as copper sulfate and chelated zinc are effective and less irritating, they can cause serious chemical pollutants such as heavy metals, which can easily cause poisoning through accidental ingestion and pose environmental risks. Although the use of antibiotics to prevent and treat hoof diseases is very popular, excessive use can lead to drug resistance.

[0007] Based on this, the purpose of the present invention is to provide a plant essential oil-based hoof bath emulsion composition and a preparation method thereof. The emulsion composition product can effectively kill hoof disease-related pathogens, does not contain heavy metals, is environmentally friendly, is non-corrosive, harmless to humans and animals, is easily soluble, and is easy to operate; can effectively prevent and treat animal hoof diseases, and can be sprayed on the lesion site of the animal, has a good preventive and therapeutic effect, and has a broad market prospect.

[0008] [Technical solution]

[0009] In order to achieve the above purpose, the technical solutions provided are as follows:

[0010] A plant essential oil-based hoof bath lotion composition comprises the following components, measured in percentage by mass: 10% to 23% plant essential oil, 10% to 23% ethanol, 1% to 5% dextrin mixture, 4% to 15% emulsifier, and 40% to 75% water; the plant essential oil is thymol or a compound of thymol and one or two of carvacrol and cinnamaldehyde.

[0011] In one embodiment, the plant essential oil-based hoof bath lotion composition comprises the following components, in percentage by mass: 10% to 20% plant essential oil, 10% to 23% ethanol, 1% to 5% dextrin mixture, 4% to 15% emulsifier, and 40% to 75% water; the plant essential oil is thymol or a compound of thymol and one or two of carvacrol and cinnamaldehyde.

[0012] In one embodiment, the dextrin mixture is a mixture of cyclodextrin and maltodextrin, and the mass ratio of cyclodextrin to maltodextrin is 1:9 to 5:5.

[0013] In one embodiment, the emulsifier is a mixture of Tween and sodium dodecyl sulfate, and the mass ratio of Tween and sodium dodecyl sulfate is 50:7.

[0014] In one embodiment, the Tween is one or more of Tween T-20, T-40, T-60, and T-80.

[0015] In one embodiment, the plant essential oil-based hoof bath lotion composition comprises the following components, in percentage by mass: 10% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate, and 66.3% water.

[0016] In one embodiment, the plant essential oil-based hoof bath lotion composition comprises the following components, in percentage by mass: 20% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 10% Tween T-80, 1.4% sodium lauryl sulfate, and 50.6% water.

[0017] In one embodiment, the plant essential oil-based hoof bath lotion composition comprises the following components, in percentage by mass: 8% thymol, 12% carvacrol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate, and 56.3% water.

[0018] In one embodiment, the plant essential oil-based hoof bath lotion composition comprises the following components, in percentage by mass: 5% thymol, 5% cinnamaldehyde, 5% carvacrol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate, and 61.3% water.

[0019] The present invention also provides a method for preparing the above-mentioned plant essential oil-based foot bath lotion, the method comprising the following steps:

[0020] (1) fully stirring and mixing plant essential oil and ethanol to obtain a uniform essential oil ethanol solution;

[0021] (2) dissolving an emulsifier in a portion of water to obtain an emulsifier solution;

[0022] (3) heating and dissolving the dextrin mixture with the remaining water to obtain a dextrin solution;

[0023] (4) Cool the dextrin solution of step (3) to 50-60° C., add the essential oil ethanol solution of step (1), stir and mix evenly, then add the emulsifier solution of step (2), continue to stir evenly, and obtain a hoof bath emulsion.

[0024] In one embodiment, the temperature of the heated solution in step (3) is 80-90°C.

[0025] The present invention also provides a plant essential oil-based hoof bath lotion prepared by the method.

[0026] The present invention also provides a hoof bath spray product, which comprises the plant essential oil-based hoof bath emulsion composition or the plant essential oil-based hoof bath emulsion described above.

[0027] The present invention also provides application of the plant essential oil-based hoof bath emulsion composition in preparing products for preventing / treating animal hoof diseases.

[0028] Beneficial effects:

[0029] The plant essential oil-based hoof bath emulsion composition prepared by the present invention can effectively kill hoof disease-related pathogens; the main components are plant essential oils, emulsifiers and water, do not contain heavy metals, and are environmentally friendly; have no irritating odor, are non-corrosive, and are harmless to humans and animals; are in liquid form, easy to dilute evenly, and are easy to operate; compared with formalin, have better preventive and therapeutic effects on animal hoof diseases, and have good preventive and therapeutic effects when sprayed on the lesion site of the animal. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work belong to the scope of protection of the present invention. The following specific implementation methods further describe the present invention.

[0031] Example 1

[0032] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 10% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate and 66.3% water.

[0033] A method for preparing a plant essential oil-based hoof bath lotion comprises the following preparation steps:

[0034] (1) fully stirring and mixing thymol and ethanol to obtain a uniform thymol ethanol solution;

[0035] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0036] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0037] (4) Cool the dextrin solution obtained in step (3) to 60° C., add it to the thymol ethanol solution in step (1), stir and mix evenly, then add the emulsifier solution in step (2), stir and mix evenly again, and obtain hoof bath lotion A.

[0038] Example 2

[0039] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 20% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 10% Tween T-80, 1.4% sodium lauryl sulfate and 50.6% water.

[0040] A method for preparing a plant essential oil-based hoof bath lotion comprises the following preparation steps:

[0041] (1) fully stirring and mixing thymol and ethanol to obtain a uniform thymol ethanol solution;

[0042] (2) After heating and dissolving sodium dodecyl sulfate with part of water, the mixture is cooled to 50° C., Tween is added, and the mixture is stirred evenly to obtain an emulsifier solution;

[0043] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0044] (4) Cool the dextrin solution obtained in step (3) to 50° C., add it to the thymol ethanol solution in step (1), stir and mix evenly, then add the emulsifier solution in step (2), stir and mix evenly again, and obtain hoof bath lotion B.

[0045] Example 3

[0046] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 8% of thymol, 12% of carvacrol, 16% of ethanol, 1% of cyclodextrin, 1% of maltodextrin, 5% of Tween T-80, 0.7% of sodium lauryl sulfate and 56.3% of water.

[0047] A method for preparing a plant essential oil-based hoof bath lotion comprises the following preparation steps:

[0048] (1) fully stirring and mixing thymol and carvacrol with ethanol to obtain a uniform plant essential oil-based solution;

[0049] (2) After heating and dissolving sodium dodecyl sulfate with a portion of water, the mixture is cooled to 55° C., Tween is added, and the mixture is stirred evenly to obtain an emulsifier solution;

[0050] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0051] (4) The dextrin solution obtained in step (3) is cooled to 55° C., added to the plant essential oil-based solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath lotion C.

[0052] Example 4

[0053] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 5% of thymol, 5% of cinnamaldehyde, 5% of carvacrol, 16% of ethanol, 1% of cyclodextrin, 1% of maltodextrin, 5% of Tween T-80, 0.7% of sodium lauryl sulfate and 61.3% of water.

[0054] A method for preparing a plant essential oil-based hoof bath lotion comprises the following preparation steps:

[0055] (1) fully stirring and mixing thymol, cinnamaldehyde, carvacrol and ethanol to obtain a uniform plant essential oil-based solution;

[0056] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0057] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0058] (4) The dextrin solution obtained in step (3) is cooled to 60° C., added to the plant essential oil-based solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath lotion D.

[0059] Comparative Example 1

[0060] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 9% of thymol, 16% of ethanol, 1% of cyclodextrin, 1% of maltodextrin, 5% of Tween T-80, 0.7% of sodium lauryl sulfate and 67.3% of water.

[0061] The preparation method comprises the following preparation steps:

[0062] (1) fully stirring and mixing thymol and ethanol to obtain a uniform thymol ethanol solution;

[0063] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0064] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0065] (4) The dextrin solution obtained in step (3) is cooled to 60° C., added to the thymol ethanol solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath emulsion E.

[0066] Comparative Example 2

[0067] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 24% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate and 52.3% water.

[0068] The preparation method comprises the following preparation steps:

[0069] (1) fully stirring and mixing thymol and ethanol to obtain a uniform thymol ethanol solution;

[0070] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0071] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0072] (4) The dextrin solution obtained in step (3) was cooled to 60° C., added to the thymol ethanol solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) was added, and stirred and mixed again, but the mixture could not be mixed evenly, and demulsification occurred, and the hoof bath emulsion could not be obtained.

[0073] Comparative Example 3

[0074] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 10% cinnamaldehyde, 10% carvacrol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate and 56.3% water.

[0075] The preparation method comprises the following preparation steps:

[0076] (1) fully stirring and mixing cinnamaldehyde, carvacrol and ethanol to obtain a uniform plant essential oil-based solution;

[0077] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0078] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0079] (4) The dextrin solution obtained in step (3) is cooled to 60° C., added to the plant essential oil-based solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath lotion F.

[0080] Comparative Example 4

[0081] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 10% oregano oil, 5% cinnamaldehyde, 5% carvacrol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate and 56.3% water.

[0082] The preparation method comprises the following preparation steps:

[0083] (1) fully stirring and mixing oregano oil, cinnamaldehyde, carvacrol and ethanol to obtain a uniform plant essential oil-based solution;

[0084] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0085] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0086] (4) Cool the dextrin solution obtained in step (3) to 60° C., add it to the plant essential oil-based solution in step (1), stir and mix evenly, then add the emulsifier solution in step (2), stir and mix evenly again, and obtain hoof bath lotion G.

[0087] Comparative Example 5

[0088] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 5% oregano oil, 5% eucalyptus oil, 5% cinnamaldehyde, 5% carvacrol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate and 56.3% water.

[0089] The preparation method comprises the following preparation steps:

[0090] (1) fully stirring and mixing oregano oil, eucalyptus oil, cinnamaldehyde, carvacrol and ethanol to obtain a uniform plant essential oil-based solution;

[0091] (2) heating and dissolving sodium dodecyl sulfate with part of water, cooling to 60° C., adding Tween, and stirring evenly to obtain an emulsifier solution;

[0092] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0093] (4) Cool the dextrin solution obtained in step (3) to 60° C., add it to the plant essential oil-based solution in step (1), stir and mix evenly, then add the emulsifier solution in step (2), stir and mix evenly again, and obtain hoof bath emulsion H.

[0094] Comparative Example 6

[0095] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 8% of thymol, 12% of eugenol, 16% of ethanol, 1% of cyclodextrin, 1% of maltodextrin, 5% of Tween T-80, 0.7% of sodium lauryl sulfate and 56.3% of water.

[0096] The preparation method comprises the following preparation steps:

[0097] (1) fully stirring and mixing thymol and eugenol with ethanol to obtain a uniform plant essential oil-based solution;

[0098] (2) After heating and dissolving sodium dodecyl sulfate with a portion of water, the mixture is cooled to 55° C., Tween is added, and the mixture is stirred evenly to obtain an emulsifier solution;

[0099] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0100] (4) The dextrin solution obtained in step (3) is cooled to 55° C., added to the plant essential oil-based solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath lotion I.

[0101] Comparative Example 7

[0102] A plant essential oil-based hoof bath lotion composition comprises the following components (by mass percentage): 8% of thymol, 6% of eugenol, 6% of oregano oil, 16% of ethanol, 1% of cyclodextrin, 1% of maltodextrin, 5% of Tween T-80, 0.7% of sodium lauryl sulfate and 56.3% of water.

[0103] The preparation method comprises the following preparation steps:

[0104] (1) fully stirring and mixing thymol, eugenol and oregano oil with ethanol to obtain a uniform plant essential oil-based solution;

[0105] (2) After heating and dissolving sodium dodecyl sulfate with a portion of water, the mixture is cooled to 55° C., Tween is added, and the mixture is stirred evenly to obtain an emulsifier solution;

[0106] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0107] (4) The dextrin solution obtained in step (3) is cooled to 55° C., added to the plant essential oil-based solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath emulsion J.

[0108] Comparative Example 8

[0109] A plant essential oil-based hoof bath lotion composition comprises the following components (in percentage by mass): 8% of thymol, 4% of eugenol, 4% of oregano oil, 4% of eucalyptus oil, 16% of ethanol, 1% of cyclodextrin, 1% of maltodextrin, 5% of Tween T-80, 0.7% of sodium lauryl sulfate and 56.3% of water.

[0110] The preparation method comprises the following preparation steps:

[0111] (1) fully stirring and mixing thymol, eugenol, oregano oil and eucalyptus oil with ethanol to obtain a uniform plant essential oil-based solution;

[0112] (2) After heating and dissolving sodium dodecyl sulfate with a portion of water, the mixture is cooled to 55° C., Tween is added, and the mixture is stirred evenly to obtain an emulsifier solution;

[0113] (3) heating the cyclodextrin and maltodextrin to 90° C. with the remaining water to dissolve them to obtain a dextrin solution;

[0114] (4) The dextrin solution obtained in step (3) is cooled to 55° C., added to the plant essential oil-based solution in step (1), stirred and mixed evenly, and then the emulsifier solution in step (2) is added, and stirred and mixed evenly again to obtain hoof bath lotion K.

[0115] Results Analysis

[0116] 1. In order to evaluate the preventive effect of plant essential oil-based hoof bath lotion on hoof disease, Fusobacterium nucleatum, a typical pathogen of hoof disease in dairy cows, was selected as a representative for bactericidal test. The mass percentage of culture medium components required by the strain is as follows: 1.5% tryptone, 0.5% soy peptone, 0.5% sodium chloride, culture conditions: 37°C, anaerobic environment (80% N2-10% CO2-10% H2). The control group was not added with hoof bath lotion, and the results are shown in Table 1.

[0117] Table 1 The killing effect of hoof bath lotion on Fusobacterium nucleatum

[0118]

[0119]

[0120] From the results in Table 1, it can be seen that the plant essential oil-based hoof bath lotion prepared by adding thymol, compounding or not compounding carvacrol and cinnamaldehyde has a good killing effect on the pathogen Fusobacterium nucleatum, indicating that it can effectively kill the pathogen of hoof disease Fusobacterium nucleatum.

[0121] When the amount of plant essential oil added is less than 10% (Comparative Example 1), the killing effect of the hoof bath lotion on Fusobacterium nucleatum is significantly weakened. When the amount of plant essential oil added is 24%, it cannot be mixed evenly during the preparation process, demulsification occurs, and no hoof bath lotion can be obtained.

[0122] When thymol was not used and other essential oils (F, G, H) were used, the killing effect of the hoof bath lotion on Fusobacterium nucleatum was significantly weakened, indicating that the plant essential oil-based hoof bath lotion formed by thymol has a better killing effect on Fusobacterium nucleatum.

[0123] When carvacrol and cinnamaldehyde were not used and other essential oils were used in combination with thymol (I, J, K), the killing effect of the hoof bath lotion on Fusobacterium nucleatum was significantly weakened, indicating that the effect of compounding other essential oils in the formula of plant essential oil-based hoof bath lotion was not as good as carvacrol and cinnamaldehyde.

[0124] 2. To verify the actual efficacy of plant essential oil-based hoof bath lotion in the prevention and treatment of animal hoof diseases, 300 dairy cows with hoof diseases were selected, and lameness was used as an indicator. They were observed once a week, and the score system was used. The higher the score, the more severe the lameness. A score of 3 or more was considered severe lameness, that is, severe hoof disease. Formalin was used as the control group, and the results are shown in Table 2:

[0125] Table 2 Actual test of hoof bath

[0126]

[0127]

[0128] The results in Table 2 show that after using the plant essential oil-based hoof bath lotions of Examples 1 to 4, the lameness rate of dairy cows was greatly reduced, and the scores were all lower than that of the formalin control group, indicating that the plant essential oil-based hoof bath lotion prepared by the present invention has a better effect on the prevention and treatment of hoof diseases.

[0129] In summary, the plant essential oil-based hoof bath lotion prepared by the present invention does not contain heavy metals and is environmentally friendly; it has no irritating odor, is non-corrosive, is harmless to humans and animals, and can effectively kill hoof disease-related pathogens, and can effectively prevent and treat animal hoof diseases.

[0130] The embodiments provided above are not intended to limit the scope of the present invention, and the steps described are not intended to limit the execution order thereof. Those skilled in the art may make obvious improvements to the present invention in combination with existing common knowledge, which also fall within the scope of protection defined by the claims of the present invention.

Claims

1. A plant essential oil-based foot bath lotion composition, characterized in that: The plant essential oil-based hoof bath lotion composition comprises the following components, calculated by mass percentage: 10% to 23% plant essential oil, 10% to 23% ethanol, 1% to 5% dextrin mixture, 4% to 15% emulsifier, and 40% to 75% water; the plant essential oil is thymol or a compound of thymol and one or two of carvacrol and cinnamaldehyde.

2. The plant essential oil-based foot bath emulsion composition according to claim 1, characterized in that: The invention comprises the following components, calculated by mass percentage: 10% to 20% of plant essential oil, 10% to 23% of ethanol, 1% to 5% of dextrin mixture, 4% to 15% of emulsifier and 40% to 75% of water; the plant essential oil is thymol or a compound of thymol and one or two of carvacrol and cinnamaldehyde.

3. The plant essential oil-based foot bath lotion composition according to claim 1, characterized in that: The dextrin mixture is a mixture of cyclodextrin and maltodextrin, and the mass ratio of cyclodextrin to maltodextrin is 1:9 to 5:

5.

4. The plant essential oil-based foot bath lotion composition according to claim 1, characterized in that: The emulsifier is a mixture of Tween and sodium dodecyl sulfate, and the mass ratio of Tween and sodium dodecyl sulfate is 50:

7.

5. The plant essential oil-based foot bath lotion composition according to claim 1, characterized in that: The plant essential oil-based hoof bath lotion composition comprises the following components, calculated by mass percentage: 10% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate, and 66.3% water.

6. The plant essential oil-based foot bath emulsion composition according to claim 1, characterized in that: The plant essential oil-based hoof bath lotion composition comprises the following components, calculated by mass percentage: 20% thymol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 10% Tween T-80, 1.4% sodium lauryl sulfate, and 50.6% water.

7. The plant essential oil-based foot bath emulsion composition according to claim 1, characterized in that: The plant essential oil-based hoof bath lotion composition comprises the following components, calculated by mass percentage: 8% thymol, 12% carvacrol, 16% ethanol, 1% cyclodextrin, 1% maltodextrin, 5% Tween T-80, 0.7% sodium lauryl sulfate, and 56.3% water.

8. A method for preparing a plant essential oil-based hoof bath lotion, characterized in that: The method uses the plant essential oil-based foot bath lotion composition according to any one of claims 1 to 7, and specifically comprises the following steps: (1) fully stirring and mixing plant essential oil and ethanol to obtain a uniform essential oil ethanol solution; (2) dissolving an emulsifier in a portion of water to obtain an emulsifier solution; (3) heating and dissolving the dextrin mixture with the remaining water to obtain a dextrin solution; (4) Cool the dextrin solution of step (3) to 50-60° C., add the essential oil ethanol solution of step (1), stir and mix evenly, then add the emulsifier solution of step (2), continue to stir evenly, and obtain a hoof bath emulsion.

9. A hoof bath spray product, characterized in that: The hoof bath spray product comprises the plant essential oil-based hoof bath lotion composition according to any one of claims 1 to 7 or the plant essential oil-based hoof bath lotion prepared by the preparation method according to claim 8.

10. Use of the plant essential oil-based hoof bath lotion composition according to any one of claims 1 to 7 or the plant essential oil-based hoof bath lotion prepared by the preparation method according to claim 8 in preparing products for preventing / treating animal hoof diseases.

Citation Information

Patent Citations

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