Novel full-automatic pipetting workstation and pipetting method

Abstract

The invention provides a novel full-automatic pipetting workstation and a pipetting method. The pipetting workstation comprises a frame, a tray mechanism, a pipetting mechanism and a control system, the tray mechanism and the pipetting mechanism are arranged in the frame; the control system is arranged on the outer side of the frame; the tray mechanism comprises a tray and a push-pull mechanism, and the tray is pulled out of or pushed into the frame through the push-pull mechanism; the pipetting mechanism comprises a plurality of injectors which are arranged side by side, the injectors are connected with a pipette through pipelines, and a pressure sensor is mounted at the upper part of the pipette. The device is simple and reasonable in structure and high in integrity, the syringe is adopted for liquid suction and liquid relief, the liquid relief accuracy is improved, the pressure sensor is installed on the upper portion of the liquid suction pipe, and the liquid relief work is safer; the tray is convenient to integrally take out and replace the pipetting bottle and the volumetric flask in a push-pull manner, so that the pipetting amount is increased; the cleaning mechanism is arranged, so that the pipetting of various different liquids is facilitated, and the pipetting working efficiency is improved; the automation degree is high, the applicability is high, and application and popularization are facilitated.

Description

Technical Field

[0001] The present invention relates to the field of automated liquid transfer technology, and in particular to a novel fully automated liquid transfer workstation and a liquid transfer method. Background Art

[0002] Pipetting operations are widely used in many industries such as chemistry, biology, medicine, and food. These industries have a large demand for pipetting operations and require high accuracy of the results.

[0003] Most of the existing pipetting work is done manually. Since the number of samples that need to be tested is large and the operators are not unique, the probability of error is increased and the work efficiency is low.

[0004] With the continuous development of the above-mentioned industries, the market demand for automatic pipetting stations is also growing. Existing pipetting workstations use peristaltic pumps to transfer liquid from one pipette bottle to another. The peristaltic pump is divided into an inlet and an outlet. The liquid to be transferred enters the inlet of the peristaltic pump through a hose and is discharged from the outlet. Although the existing pipetting method can achieve the effect of pipetting, it has the following obvious defects: 1. Although the flow value of the peristaltic pump is measured in the laboratory, it is not a fixed value and will change due to factors such as the working environment, measuring medium, and hose size. Therefore, there will be a large error in the transfer of liquid by the peristaltic pump, and the pipetting accuracy is low.

[0005] 2. The hose in the peristaltic pump has a lifespan and needs to be replaced frequently, which increases material and labor costs.

[0006] 3. The pipetting volume is small, generally less than 1 ml, which cannot meet the pipetting needs of more than 1 ml, and its applicability in application scenarios is low.

[0007] 4. Most pipette tips are made of plastic and are disposable. They need to be replaced after use, which increases time and material costs. Summary of the invention

[0008] In view of this, the purpose of the present invention is to design a new type of fully automated pipetting workstation and pipetting method, in which the pipetting mechanism uses a syringe to aspirate and pipette to improve the accuracy of pipetting, and a pressure sensor is installed on the upper part of the pipette to prevent the bottom of the pipette from hitting the volumetric flask due to inaccurate position during pipetting and causing damage to the equipment, making the pipetting work safer; the tray can be pushed and pulled to facilitate the removal and replacement of the pipette bottle and the volumetric flask as a whole, thereby increasing the pipetting volume; a cleaning mechanism is configured to facilitate the pipetting of a variety of different liquids and improve the efficiency of pipetting work.

[0009] The present invention provides a novel fully automated liquid transfer workstation, comprising: a frame, a tray mechanism, a liquid transfer mechanism, and a control system; the tray mechanism and the liquid transfer mechanism are both arranged inside the frame, and the control system is arranged outside the frame; The tray mechanism comprises a tray and a push-pull mechanism, wherein the push-pull mechanism is connected to the tray in a movable transmission manner, wherein a plurality of pipettes and volumetric bottles arranged in a uniform array are loaded in the tray, wherein the tray can be driven by the push-pull mechanism to reciprocate between the inside and outside of the frame, and the volumetric bottles can be replaced in batches by pulling the tray out of or pushing it into the frame. The present invention pulls the tray out of the frame to replace the volumetric bottles, which is more convenient than replacing the volumetric bottles in the pipetting workstation in the prior art; after the volumetric bottles are replaced, the tray is pushed in; The pipetting mechanism includes a plurality of (preferably 4) syringes arranged side by side, and the syringes are used to suck and inject liquid, and each of the syringes is connected to a pipette through a pipeline, and a pressure sensor is installed on the upper part of the pipette. The use of syringes has higher pipetting accuracy, and the syringes can be reused many times, which greatly reduces the material cost and replacement time cost.

[0010] Furthermore, the syringe is connected to a ball screw mechanism, which includes a screw and a ball nut. The ball nut moves up and down along the screw, and the piston of the syringe is fixedly connected to the ball nut; the injection head of the syringe is connected to the pipette. The up and down movement of the ball nut of the ball screw mechanism drives the syringe to draw or push.

[0011] Furthermore, the frame is provided with a left-right moving drive mechanism and an up-down moving drive mechanism, and the up-down moving drive mechanism is fixed to the left-right moving drive mechanism through a crossbeam to form a two-axis mechanical arm to realize the movement of the liquid transfer mechanism; the liquid transfer mechanism is connected to the up-down moving drive mechanism. The control system is connected to the left-right moving drive mechanism and the up-down moving drive mechanism respectively by signal.

[0012] The control system controls the start and stop of the whole machine mechanism of the new fully automated liquid transfer workstation. The left-right moving drive mechanism realizes the left-right movement of the liquid transfer mechanism; the up-down moving drive mechanism realizes the up-down movement of the liquid transfer mechanism.

[0013] Furthermore, a cleaning mechanism is also provided inside the frame, and the cleaning mechanism is fluidly connected to the pipetting mechanism after the pipetting is completed. The cleaning mechanism includes a cleaning tank and a water pump. The cleaning tank is equipped with a liquid level sensor, the water pump is fluidly connected to the cleaning tank, and the liquid level sensor is signal-connected to the water pump.

[0014] During the cleaning process, the cleaning liquid is added into the cleaning tank through the water pump. When the water level in the cleaning tank reaches the required level, the water pump stops working. The cleaning process is that the liquid pipette is repeatedly pushed and cleaned by the syringe in the cleaning tank, and the waste water of the cleaning liquid is discharged through another water pump; Furthermore, the left-right moving drive mechanism adopts a synchronous wheel transmission mechanism, and the synchronous wheel transmission mechanism includes: a synchronous wheel and a synchronous belt. The synchronous belt is mounted on the synchronous wheel, and a slider is fixedly connected to the synchronous belt. The synchronous wheel is driven to rotate by the left-right moving drive motor, and the rotation of the synchronous wheel drives the synchronous belt to move, and the synchronous belt drives the slider to move in the left-right direction.

[0015] Furthermore, the up-and-down movement driving mechanism adopts a gear rack mechanism, which includes: a gear, a rack, and a guide rail. The rack and the guide rail are fixedly installed together, and the gear rolls up and down along the rack; the gear is driven to rotate by an up-and-down movement driving motor, and the gear rotation drives the rack to move, and the guide rail moves up and down with the rack.

[0016] The present invention also provides a novel fully automated liquid transfer method, which is applied to the novel fully automated liquid transfer workstation as described above, and comprises the following steps: The control system controls the left-right moving driving mechanism to move to the liquid suction position, and the up-down moving driving mechanism moves downward to move the liquid transfer mechanism downward, and the liquid transfer tube connected to the syringe enters the bottom of the liquid transfer bottle, and the syringe performs suction to suck the liquid into the pipeline connected to the liquid transfer tube; The up-down moving driving mechanism moves upward to drive the liquid transfer mechanism to move upward, the left-right moving driving mechanism moves to the liquid transfer position, and the up-down moving driving mechanism moves downward to move the liquid transfer mechanism downward, the pipette connected to the syringe enters the bottom of the volumetric flask, and the syringe performs push injection to push the liquid in the pipeline connected to the pipette into the volumetric flask; The up-and-down moving drive mechanism moves upward to drive the pipetting mechanism to move upward, the left-and-right moving drive mechanism moves to the cleaning position, and the up-and-down moving drive mechanism moves downward to move the pipetting mechanism downward, and the pipette connected to the syringe is extended into the cleaning tank to clean the pipette; when the liquid loss in the cleaning tank exceeds the set liquid level threshold, the liquid level sensor sends a signal to the water pump to start the water pump to replenish the cleaning tank with cleaning liquid.

[0017] Furthermore, when the bottom of the pipette touches the pipette bottle or volumetric flask, the pipette feeds back an upward force to the pressure sensor, and the pressure sensor sends a signal to the control system. The control system controls the corresponding mechanism to perform a protective action to prevent the bottom of the pipette from touching the pipette bottle or volumetric flask due to inaccurate position during pipetting, thereby avoiding damage to the equipment.

[0018] The present invention also provides a computer-readable storage medium having a computer program stored thereon, wherein when the program is executed by a processor, the steps of the novel fully-automatic pipetting method as described above are implemented.

[0019] The present invention also provides a computer device, which includes a memory, a processor, and a computer program stored in the memory and executable on the processor, wherein the processor implements the steps of the novel fully automated pipetting method as described above when executing the program.

[0020] Compared with the prior art, the present invention has the following beneficial effects: The novel fully automated liquid transfer workstation and liquid transfer method provided by the present invention have a simple and reasonable structure and strong integrity. The liquid transfer mechanism adopts a syringe to aspirate and transfer liquid, which improves the accuracy of liquid transfer. A pressure sensor is installed on the upper part of the liquid transfer tube to prevent the bottom of the liquid transfer tube from hitting the volumetric flask due to inaccurate position during liquid transfer and causing damage to the equipment, thereby making the liquid transfer work safer. The tray can be conveniently taken out and replaced as a whole by pushing and pulling, thereby increasing the liquid transfer volume. A cleaning mechanism is configured to facilitate the transfer of a variety of different liquids, effectively improving the efficiency of liquid transfer work. In addition, the labor cost and material cost are reduced, the degree of automation is high, the applicability is strong, and the liquid transfer work has broad prospects for promotion and application. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Various other advantages and benefits will become apparent to those of ordinary skill in the art by reading the following detailed description of the preferred embodiment.The drawings are only for the purpose of illustrating the preferred embodiments and are not to be construed as limiting the invention.

[0022] In the attached picture: Figure 1 This is an axonometric diagram of the overall structure installation of a new fully automated liquid transfer workstation according to an embodiment of the present invention; Figure 2 This is a front view of the overall installation structure of a new fully automated liquid transfer workstation according to an embodiment of the present invention; Figure 3 A structural diagram of a framework of an embodiment of the present invention; Figure 4 It is an installation diagram of the left-right direction moving driving mechanism of an embodiment of the present invention; Figure 5 A diagram showing the structural components of a left-right direction moving drive mechanism according to an embodiment of the present invention; Figure 6 It is an installation diagram of the up-down direction moving driving mechanism of an embodiment of the present invention; Figure 7 A structural member diagram of a vertically movable driving mechanism according to an embodiment of the present invention; Figure 8It is an installation diagram of the left-right direction moving driving mechanism and the up-down direction moving driving mechanism in the frame according to an embodiment of the present invention; Fig. 9 A schematic diagram of a tray mechanism according to an embodiment of the present invention being pulled out from a frame; Fig.10 A schematic diagram of a tray mechanism according to an embodiment of the present invention being pushed back into a frame; Fig.11 is a structural diagram of a liquid transfer mechanism according to an embodiment of the present invention; Fig.12 FIG. 1 is a diagram showing the installation position of a pressure sensor according to an embodiment of the present invention; Fig.13 It is a front view of the installation of the syringe and the ball screw mechanism according to the embodiment of the present invention; Fig.14 It is an installation isometric view of a syringe and a ball screw mechanism according to an embodiment of the present invention; Fig.15 A structural component diagram of a cleaning mechanism according to an embodiment of the present invention; Fig.16 A structural diagram of a cleaning mechanism discharging cleaning liquid according to an embodiment of the present invention; Fig.17 A flow chart of a novel fully automated liquid transfer method according to an embodiment of the present invention; Fig.18 The figure is a schematic diagram of the structure of a computer device according to an embodiment of the present invention. The symbols in the accompanying drawings are: 1. Frame; 2. Left-right moving drive mechanism; 3. Up-down moving drive mechanism; 4. Tray mechanism; 5. Liquid transfer mechanism; 6. Cleaning mechanism; 7. Control system; 8. Synchronous wheel; 9. Synchronous belt; 10. Slider; 11. Left-right moving drive motor; 12. Gear; 13. Rack; 14. Guide rail; 15. Up-down moving drive motor; 16. Crossbeam; 17. Ball nut; 18. Screw rod; 19. Water pump; 20. Cleaning tank; 21. Liquid level sensor; 22. Pressure sensor; 23. Syringe. DETAILED DESCRIPTION

[0023] Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, the same numbers in different drawings represent the same or similar elements unless otherwise indicated. The implementations described in the following exemplary embodiments do not represent all implementations consistent with the present disclosure. Instead, they are merely examples of systems and products consistent with some aspects of the present disclosure as detailed in the appended claims.

[0024] The terms used in this disclosure are for the purpose of describing specific embodiments only and are not intended to limit the disclosure. The singular forms of "a", "said" and "the" used in this disclosure and the appended claims are also intended to include plural forms unless the context clearly indicates otherwise. It should also be understood that the term "and / or" used herein refers to and includes any or all possible combinations of one or more associated listed items.

[0025] It should be understood that although the terms first, second, third, etc. may be used in the present disclosure to describe various information, such information should not be limited to these terms. These terms are only used to distinguish the same type of information from each other. For example, without departing from the scope of the present disclosure, the first information may also be referred to as the second information, and similarly, the second information may also be referred to as the first information. Depending on the context, the word "if" as used herein may be interpreted as "at the time of" or "when" or "in response to determining".

[0026] The embodiments of the present invention are described in further detail below.

[0027] The present invention provides a novel fully automated liquid transfer workstation. Figure 1 , 2 , 3, comprising: a frame 1, a tray mechanism 4, a pipetting mechanism 5, and a control system 7; the tray mechanism 7 comprises a tray and a push-pull mechanism, wherein a plurality of pipettes and volumetric bottles arranged in a uniform array are loaded in the tray, and the tray is driven by the push-pull mechanism to reciprocate between the inside and the outside of the frame 1, and the tray is pulled out of or pushed into the frame 1 (such as Fig. 9 As shown), the volumetric bottles can be replaced in batches. In this embodiment, the tray is pulled out to the outside of the frame 1 to replace the volumetric bottles. Compared with the prior art, it is more convenient to replace the volumetric bottles in the pipetting workstation and the pipetting volume is increased. After the volumetric bottles are replaced, the tray is pushed in (as shown in FIG. Fig.10 shown); The frame 1 is provided with a left-right direction moving driving mechanism 2 and a vertical direction moving driving mechanism 3. The vertical direction moving driving mechanism 3 is fixed to the left-right direction moving driving mechanism 2 through a crossbeam 16 (see Figure 8 As shown in the figure), a two-axis mechanical arm is formed to realize the movement of the pipetting mechanism; the pipetting mechanism 5 is connected to the up-down moving drive mechanism 3. The control system 7 is connected to the left-right moving drive mechanism 2 and the up-down moving drive mechanism (3) respectively. The control system 7 controls the start and stop of the whole machine mechanism of the new fully automated pipetting workstation. The left-right moving drive mechanism 2 realizes the left-right movement of the pipetting mechanism; the up-down moving drive mechanism 3 realizes the up-down movement of the pipetting mechanism.

[0028] In this embodiment, the left-right direction moving driving mechanism 2 adopts a synchronous wheel transmission mechanism (see 4 and 5), and the left-right direction moving driving motor 11 drives the synchronous wheel 8 to rotate, and the synchronous wheel 8 rotates to drive the synchronous belt 9 to move, and the synchronous belt 9 drives the slider 10 to move in the left-right direction. The up-down direction moving driving mechanism (3) adopts a gear rack mechanism (see 6 and 7), and the up-down direction moving driving motor 15 drives the gear 12 to rotate, and the gear 12 rotates to drive the rack 13 to move, and the guide rail 14 moves up and down with the rack 13.

[0029] The liquid transfer mechanism 5 includes four syringes 23 arranged side by side, and the syringes 23 are used to suck and inject liquid. Each syringe 23 is connected to a pipette (such as Fig.11 As shown in the figure, the pressure sensor is installed on the upper part of the pipette (see Fig.12 As shown); the syringe 23 can be reused, which reduces the material cost and the replacement time cost, and the syringe 23 is used to achieve higher pipetting accuracy. The syringe 23 is connected to a ball screw mechanism (see Fig.13 , 14 As shown in FIG. 1 ), the ball screw mechanism includes a screw 18 and a ball nut 17. The ball nut 17 moves up and down along the screw 18. The piston of the syringe is fixedly connected to the ball nut 17. The injection head of the syringe is connected to the pipette. The up and down movement of the ball nut 17 of the ball screw mechanism drives the syringe to draw or push.

[0030] The frame 1 is also provided with a cleaning mechanism 6 (see Fig.15 As shown in the figure, the cleaning mechanism 6 is connected to the pipetting mechanism 5 after the pipetting is completed. The cleaning mechanism 6 includes a cleaning tank 20 and a water pump 19. The cleaning tank 20 is equipped with a liquid level sensor 21. The water pump 19 is connected to the cleaning tank 20, and the liquid level sensor 21 is connected to the water pump 19 by signal. When cleaning, the cleaning liquid is added to the cleaning tank 20 through the water pump 19 (see Fig.16 As shown in FIG. 1 ), when the water level in the cleaning tank 20 reaches the required level, the pump 19 stops working. The cleaning process is that the pipette is repeatedly pushed and cleaned by the syringe in the cleaning tank 20, and the cleaning liquid wastewater is discharged through another pump (see FIG. Fig.17 shown); The present invention also provides a novel fully automated liquid transfer method, which is applied to the novel fully automated liquid transfer workstation as described above, see Fig.17 As shown, the following steps are included: The control system 7 controls the left-right moving driving mechanism 2 to move to the liquid suction position, and the up-down moving driving mechanism 3 moves downward to move the liquid transfer mechanism 5 downward, and the liquid transfer tube connected to the syringe enters the bottom of the liquid transfer bottle, and the syringe performs suction to suck the liquid into the pipeline connected to the liquid transfer tube; The up-down moving driving mechanism 3 moves upward to drive the liquid transfer mechanism 5 to move upward, the left-right moving driving mechanism 2 moves to the liquid transfer position, and the up-down moving driving mechanism 3 moves downward to move the liquid transfer mechanism 5 downward, the pipette connected to the syringe enters the bottom of the volumetric flask, and the syringe performs push injection to push the liquid in the pipeline connected to the pipette into the volumetric flask; The upward movement driving mechanism 3 moves upward to drive the pipetting mechanism 5 to move upward, the left-right movement driving mechanism 2 moves to the cleaning position, and the downward movement driving mechanism 3 moves downward to move the pipetting mechanism 5 downward, and the pipette connected to the syringe is extended into the cleaning tank 20 to clean the pipette; when the liquid loss in the cleaning tank 20 exceeds the set liquid level threshold, the liquid level sensor 21 sends a signal to the water pump 19, and the water pump 19 is started to replenish the cleaning tank 20 with cleaning liquid.

[0031] When the bottom of the pipette touches the pipette bottle or the volumetric flask, the pipette feeds back an upward force to the pressure sensor 22, and the pressure sensor 22 sends a signal to the control system 7, and the control system 7 controls the corresponding mechanism to perform a protective action to prevent the bottom of the pipette from touching the pipette bottle or the volumetric flask due to inaccurate position during pipetting, thereby avoiding damage to the equipment (such as Fig.12 ), reducing material replacement costs.

[0032] An embodiment of the present invention further provides a computer device, Fig.18 is a schematic diagram of the structure of a computer device provided by an embodiment of the present invention; see the accompanying drawings Fig.18 As shown, the computer device includes: an input system 23, an output system 24, a memory 22 and a processor 21; the memory 22 is used to store one or more programs; when the one or more programs are executed by the one or more processors 21, the one or more processors 21 implement the new fully automated pipetting method provided in the above embodiment; wherein the input system 23, the output system 24, the memory 22 and the processor 21 can be connected by a bus or other means, Fig.18 The example of connecting through bus is taken in the following.

[0033] The memory 22 is a readable and writable storage medium of a computing device, which can be used to store software programs and computer executable programs, such as program instructions corresponding to the new fully automated pipetting method described in the embodiment of the present invention; the memory 22 can mainly include a program storage area and a data storage area, wherein the program storage area can store an operating system and at least one application required for a function; the data storage area can store data created according to the use of the device, etc.; in addition, the memory 22 can include a high-speed random access memory, and can also include a non-volatile memory, such as at least one disk storage device, a flash memory device, or other non-volatile solid-state storage device; in some instances, the memory 22 can further include a memory remotely arranged relative to the processor 21, and these remote memories can be connected to the device via a network. Examples of the above-mentioned network include, but are not limited to, the Internet, an intranet, a local area network, a mobile communication network, and combinations thereof.

[0034] The input system 23 may be used to receive input digital or character information, and to generate key signal input related to user settings and function control of the device; the output system 24 may include display devices such as display screens.

[0035] The processor 21 executes the software programs, instructions and modules stored in the memory 22 to perform various functional applications and data processing of the device, that is, to realize the above-mentioned novel fully automated pipetting method.

[0036] The computer device provided above can be used to execute the novel fully automated liquid transfer method provided in the above embodiment, and has corresponding functions and beneficial effects.

[0037] The embodiment of the present invention also provides a storage medium containing computer executable instructions, which are used to execute the new fully automated pipetting method provided by the above embodiment when executed by a computer processor. The storage medium is any of various types of memory devices or storage devices, and the storage medium includes: installation media, such as CD-ROM, floppy disk or tape system; computer system memory or random access memory, such as DRAM, DDR RAM, SRAM, EDORAM, Rambus RAM, etc.; non-volatile memory, such as flash memory, magnetic media (such as hard disk or optical storage); registers or other similar types of memory elements, etc.; the storage medium may also include other types of memory or a combination thereof; in addition, the storage medium may be located in a first computer system in which the program is executed, or may be located in a different second computer system, which is connected to the first computer system via a network (such as the Internet); the second computer system may provide program instructions to the first computer for execution. The storage medium includes two or more storage media that can reside in different locations (for example, in different computer systems connected via a network). The storage medium can store program instructions (for example, specifically implemented as a computer program) that can be executed by one or more processors.

[0038] Of course, the storage medium containing computer executable instructions provided in an embodiment of the present invention is not limited to the new fully automated pipetting method described in the above embodiment, and can also execute related operations in the new fully automated pipetting method provided in any embodiment of the present invention. So far, the technical solutions of the present invention have been described in conjunction with the preferred embodiments shown in the accompanying drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will fall within the protection scope of the present invention.

[0039] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A new type of fully automated liquid transfer workstation, characterized in that: include: A frame (1), a tray mechanism (4), a liquid transfer mechanism (5), and a control system (7); the tray mechanism (4) and the liquid transfer mechanism (5) are both arranged inside the frame (1), and the control system (7) is arranged outside the frame (1); The tray mechanism (7) comprises a tray and a push-pull mechanism, wherein the push-pull mechanism is connected to the tray in a movably driven manner, wherein a plurality of pipettes and volumetric bottles arranged in a uniform array are loaded in the tray, and the tray is driven by the push-pull mechanism to reciprocate between the inside and the outside of the frame (1), thereby pulling the tray out of or pushing it into the frame (1); The liquid transfer mechanism (5) comprises a plurality of syringes (25) arranged side by side, each of the syringes (23) is connected to a liquid pipette via a pipeline, and a pressure sensor (22) is installed on the upper part of the liquid pipette.

2. The novel fully automated liquid transfer workstation according to claim 1 is characterized in that: The syringe is connected to a ball screw mechanism, the ball screw mechanism comprising a screw (18) and a ball nut (17), the ball nut (17) moves up and down along the screw (18), the piston portion of the syringe is fixedly connected to the ball nut (17); the injection head of the syringe is fluidically connected to a pipette.

3. The novel fully automated liquid transfer workstation according to claim 1 is characterized in that: The frame (1) is also provided with a left-right moving drive mechanism (2) and an up-down moving drive mechanism (3) inside. The up-down moving drive mechanism (3) is fixed to the left-right moving drive mechanism (2) via a crossbeam (16). The liquid transfer mechanism (5) is connected to the up-down moving drive mechanism (3). The control system (7) is signal-connected to the left-right moving drive mechanism (2) and the up-down moving drive mechanism (3), respectively.

4. The novel fully automated liquid transfer workstation according to claim 1 is characterized in that: A cleaning mechanism (6) is also provided inside the frame (1). The cleaning mechanism (6) is fluidly connected to the pipetting mechanism (5) after the pipetting is completed. The cleaning mechanism (6) comprises a cleaning tank (20) and a water pump (19). The cleaning tank (20) is provided with a liquid level sensor (21). The water pump (19) is fluidly connected to the cleaning tank (20). The liquid level sensor (21) is signal-connected to the water pump (19).

5. The novel fully automated liquid transfer workstation according to claim 3 is characterized in that: The left-right moving drive mechanism (2) adopts a synchronous wheel transmission mechanism, which comprises: a synchronous wheel (8) and a synchronous belt (9), wherein the synchronous belt (9) is sleeved on the synchronous wheel (8), and a slider (10) is fixedly connected to the synchronous belt (9). The synchronous wheel (8) is driven to rotate by a left-right moving drive motor, and the synchronous wheel (8) rotates to drive the synchronous belt (9) to move, and the synchronous belt (9) drives the slider (10) to move in the left-right direction.

6. The novel fully automated liquid transfer workstation according to claim 3 is characterized in that: The up-and-down movement driving mechanism (3) adopts a gear rack mechanism, which comprises: a gear (12), a rack (13), and a guide rail (14); the rack (13) and the guide rail (14) are fixedly mounted together, and the gear (12) rolls up and down along the rack (13); the gear (12) is driven to rotate by an up-and-down movement driving motor, and the gear (12) rotates to drive the rack (13) to move, and the guide rail (14) moves up and down along with the rack (13).

7. A novel fully automated liquid transfer method, applied to a novel fully automated liquid transfer workstation according to any one of claims 1 to 6, characterized in that: The following steps are involved: The control system (7) controls the left-right moving driving mechanism (2) to move to the liquid aspiration position, and the up-down moving driving mechanism (3) moves downward to move the liquid transfer mechanism (5) downward, so that the liquid transfer tube connected to the syringe enters the bottom of the liquid transfer bottle, and the syringe performs suction to suck the liquid into the pipeline connected to the liquid transfer tube; The vertical moving driving mechanism (3) moves upward to drive the liquid transfer mechanism (5) to move upward, the horizontal moving driving mechanism (2) moves to the liquid transfer position, the vertical moving driving mechanism (3) moves downward to move the liquid transfer mechanism (5) downward, the liquid pipette connected to the syringe enters the bottom of the volumetric flask, and the syringe performs push injection to push the liquid in the pipeline connected to the liquid pipette into the volumetric flask; The vertical movement driving mechanism (3) moves upward to drive the pipetting mechanism (5) to move upward, the horizontal movement driving mechanism (2) moves to the cleaning position, and the vertical movement driving mechanism (3) moves downward to move the pipetting mechanism (5) downward, so that the pipette connected to the syringe is inserted into the cleaning tank (20) to clean the pipette; when the liquid loss in the cleaning tank (20) exceeds the set liquid level threshold, the liquid level sensor (21) sends a signal to the water pump (19), so that the water pump (19) is started to replenish the cleaning tank (20) with cleaning liquid.

8. The novel fully automated liquid transfer method according to claim 7, characterized in that: When the bottom of the pipette touches the pipette bottle or the volumetric flask, the pipette feeds back an upward force to the pressure sensor (22), and the pressure sensor (22) sends a signal to the control system (7). The control system (7) controls the corresponding mechanism to perform a protective action to prevent the bottom of the pipette from touching the pipette bottle or the volumetric flask due to inaccurate position during pipetting, thereby avoiding damage to the equipment.

9. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the program is executed by a processor, the steps of the novel fully automated pipetting method according to claim 7 or 8 are implemented.

10. A computer device, comprising a memory, a processor, and a computer program stored in the memory and executable on the processor, characterized in that: When the processor executes the program, the steps of the novel fully automated pipetting method as described in claim 7 or 8 are implemented.

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