Homogeneous colloid mill equipment for reducing viscosity of recombinant mussel mucoprotein

Abstract

The homogeneous colloid mill equipment comprises a colloid mill body and a circulating filtering tank, a feeding hopper is installed at a feeding opening of the colloid mill body, a first discharging pipe is connected to a discharging opening of the feeding hopper, a circulating branch is further connected to the first discharging pipe, and a second discharging pipe is connected to the circulating branch. The top end of the circulating branch is communicated with the bottom of the circulating filtering tank; a second discharging pipe is arranged at the bottom end of one side, close to the colloid mill body, of the circulating filtering tank; a filter is mounted in the circulating filtering tank; and an automatic opening and closing device is fixed at the bottom end of the filter. Compared with the prior art, the recombined mussel mucin homogenizing device has the advantages that materials with large particles in the early stage can be subjected to circulating homogenizing treatment, the gap between the movable grinding disc and the static grinding disc is reduced after a period of time, finer homogenizing treatment is carried out, the materials with different particle states can be treated in a targeted manner, the viscosity of recombined mussel mucin is effectively reduced, and the overall treatment effect is improved.

Description

Technical Field

[0001] The invention relates to the technical field of mussel mucin processing, in particular to a homogenizing colloid mill device for reducing the viscosity of recombinant mussel mucin. Background Art

[0002] In modern industrial production and many scientific research application fields, mussel mucin has received extensive attention and application due to its unique biological activity and excellent adhesion properties. As a product obtained through specific biotechnology means, recombinant mussel mucin has shown great application potential in many industries such as medicine, biomaterials, and cosmetics.

[0003] However, recombinant mussel mucin usually has a high viscosity, which greatly limits its further processing, use and optimization of product performance. For example, when it is used to prepare some fine biological coating materials, too high viscosity may lead to uneven coating, affecting its adhesion effect and the quality stability of the final product; in the medical field, if it is used as a drug carrier or a component of medical dressings, high viscosity will hinder its uniform mixing with other active ingredients and may also affect its spreading and absorption effect on the surface of human tissue.

[0004] Traditional homogenizing equipment often fails to efficiently and accurately control the degree of treatment during the process of emulsifying, dispersing and refining particles to reduce viscosity, resulting in either poor treatment results, failure to reduce viscosity to the ideal range, or excessive treatment that affects the active structure of the protein itself. Moreover, in the links of material circulation and filtration and separation of materials in different states, the existing devices lack effective coordination and coordination, which is prone to problems such as material blockage, insufficient filtration, and energy waste, making it difficult to meet the requirements of industrial large-scale production and high-precision application scenarios for accurate reduction of the viscosity of recombinant mussel mucin. Summary of the invention

[0005] In order to solve the problems mentioned in the above background technology, the present invention provides a homogenizing colloid mill device for reducing the viscosity of recombinant mussel mucin.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions: A homogenizing colloid mill device for reducing the viscosity of recombinant mussel mucin comprises a colloid mill body and a circulation filter tank, wherein a feed hopper is installed at a feed inlet of the colloid mill body, a first discharge pipe is connected to a discharge port of the feed hopper, a circulation branch is further connected to the first discharge pipe, a top end of the circulation branch is connected to a bottom of the circulation filter tank, and a second discharge pipe is arranged at a bottom end of a side of the circulation filter tank close to the colloid mill body; A filter is installed inside the circulation filter tank, and an automatic opener and closeer is fixed at the bottom of the filter. The automatic opener and closeer switches the circulation state and the filtering state by opening and closing. A suction pipe is installed near the top of the circulation filter tank on the side away from the colloid mill body.

[0007] Preferably, the filter is movably installed inside the circulating filter tank, and an arc-shaped lifting bar is movably installed on the side wall of the circulating filter tank close to the second discharge pipe. A notch is provided on the filter and the automatic opener for the arc-shaped lifting bar to pass through, and an arc-shaped sealing plate is elastically installed on the bottom end of the arc-shaped lifting bar.

[0008] Preferably, a guide column is fixed to the bottom end of the arc-shaped lifting strip, the guide column movably passes through the arc-shaped blocking plate, and a first return spring is installed outside the guide column.

[0009] Preferably, a first threaded tube is fixed to the top of the arc-shaped lifting strip, a second threaded tube is fixed to the top of the filter, a first threaded rod and a second threaded rod are rotatably installed in the circulation filter tank, and the first threaded tube and the second threaded tube are threadedly installed on the outside of the first threaded rod and the second threaded rod respectively.

[0010] Preferably, the top ends of the first threaded rod and the second threaded rod both extend to the outside of the circulation filter tank and are respectively fixed with a first spur gear and a second spur gear.

[0011] Preferably, a rotating motor is fixedly installed on the top of the circulating filter tank, and a third spur gear is fixed on the output shaft of the rotating motor. The first spur gear and the second spur gear are respectively meshed with the third spur gear from both sides of the third spur gear, and the diameter of the first spur gear is smaller than the diameter of the second spur gear.

[0012] Preferably, a vertical rotating shaft is rotatably installed at the center position of the filter, the bottom end of the vertical rotating shaft extends to the bottom of the filter and is fixed with multiple scrapers, the top end of the vertical rotating shaft extends to the top of the filter and is fixed with a first bevel gear on the outside, and a transmission horizontal shaft is also rotatably installed above the filter, a second bevel gear is fixed to the end of the transmission horizontal shaft close to the vertical rotating shaft, the second bevel gear is meshed with the first bevel gear, a fourth spur gear is fixed to the end of the transmission horizontal shaft away from the vertical rotating shaft, a vertical groove is opened on the side of the arc-shaped lifting bar close to the vertical rotating shaft, a first rack is fixed on the side wall of the vertical groove, and the fourth spur gear is meshed with the first rack.

[0013] Preferably, a vertical baffle is rotatably mounted on the outside of the transmission horizontal shaft, and the vertical baffle is movably mounted in the vertical groove for lifting.

[0014] Preferably, the vertical rotating shaft is hollow inside, and a lifting vertical shaft is movably installed in the vertical rotating shaft, a second reset spring is installed on the outer side of the lifting vertical shaft, a plurality of fan-shaped openings are opened on the automatic opener and closer, a fan-shaped sealing plate is rotatably installed in the fan-shaped opening, a fifth spur gear is fixed on the mounting rotating shaft of the fan-shaped sealing plate, a plurality of second racks are fixed on the bottom end of the lifting vertical shaft, each second rack is respectively meshed with a fifth spur gear, a disc is fixed on the top end of the lifting vertical shaft, a trigger rod is fixed on the inner wall of the top end of the circulating filter tank, and the trigger rod corresponds to the disc.

[0015] Preferably, one end of the suction pipe extends to the interior of the circulation filter tank and extends vertically downward, and a telescopic pipe is vertically movably installed inside the circulation filter tank, and the bottom end of the telescopic pipe is fixedly connected to the filter.

[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. It can firstly carry out circulating homogenization treatment on the materials with larger particles in the early stage. After a period of time, the gap between the moving grinding disc and the static grinding disc is adjusted to be smaller for more refined homogenization treatment. It can specifically treat materials with different particle states, more effectively reduce the viscosity of recombinant mussel viscose, and improve the overall treatment effect; 2. The material can be returned to the feed hopper through the circulation branch for circulation treatment, so that the material can pass through the colloid mill body and the circulation filter tank for many times, fully realizing the emulsification, dispersion, homogenization and crushing processes to ensure the adequacy of the treatment; 3. In the filtering state, the filter screen on the filter can be used to filter the materials with high emulsification degree and small particle size. With the suction force of the suction pump, the filtered materials can be drawn out from the suction pipe and collected, realizing the separation and collection of materials in different states; 4. The relative displacement between the arc-shaped lifting bar and the filter can compress the front lower space when the filter is pressed down, so that the material can pass through the filter faster under pressure, thereby improving the filtration efficiency. When the filter moves, a series of gears, shafts and other transmission structures can drive the scraper to clean the accumulated filtered materials at the bottom of the filter, thereby avoiding the accumulation of filtered materials affecting the filtration effect and further ensuring the filtration efficiency. 5. The automatic opener and closer can realize the automatic opening and closing of the fan-shaped opening when the filter moves up and down by cooperating with the lifting vertical shaft and other components. When the filter is at the highest position, the fan-shaped opening is blocked. When it moves downward, the fan-shaped opening will open automatically and quickly, which is convenient for controlling the flow direction of the material and the switching of the filtering and circulation states. The telescopic tube set at the suction pipe can move downward with the filter, which can effectively prevent the occurrence of empty suction and ensure the normal and stable suction process. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0018] Figure 1 It is an overall schematic diagram of the present invention; Figure 2 A diagram of a separate circulation filter tank according to the present invention; Figure 3 It is a cross-sectional view of the circulation filtration of the present invention; Figure 4 This is an enlarged detail view of the filter of the present invention from the first viewing angle; Figure 5 This is an enlarged detail view of the filter of the present invention from a second viewing angle; Figure 6 This is an enlarged detail view of the filter of the present invention from a third viewing angle; Figure 7 This is a schematic diagram of the scraper distribution at the bottom of the filter of the present invention; Figure 8 A detailed diagram of the cooperation between the first bevel gear and the second bevel gear of the present invention; Fig. 9 for Figure 8 A zoomed-in detail of position A in the middle; Fig.10 It is a schematic diagram of the matching relationship between the fifth spur gear and the second rack of the present invention from a first viewing angle; Fig.11 is a schematic diagram of the matching relationship between the fifth spur gear and the second rack of the present invention from a second viewing angle; Fig.12 for Fig.11 Enlarged detail of position B in the middle; In the figure: 1. colloid mill body; 101. feed hopper; 102. first discharge pipe; 103. circulation branch; 2. circulation filter tank; 201. second discharge pipe; 202. suction pipe; 2021. telescopic pipe; 203. first threaded rod; 204. second threaded rod; 205. second spur gear; 206. first spur gear; 207. rotating motor; 208. third spur gear; 209. trigger rod; 3. filter; 301. filter screen; 302. second threaded pipe; 4. automatic opener and closeer; 401. Sector-shaped blocking plate; 402, fifth spur gear; 5, arc-shaped lifting strip; 501, first threaded tube; 502, vertical groove; 503, first rack; 504, guide column; 505, arc-shaped blocking plate; 506, first return spring; 6, vertical rotating shaft; 601, first bevel gear; 602, transmission horizontal shaft; 603, second bevel gear; 604, fourth spur gear; 605, vertical baffle; 606, scraper; 7, lifting vertical shaft; 701, disc; 702, second return spring; 703, second rack. DETAILED DESCRIPTION

[0019] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Example 1

[0020] Reference Figure 1-12 A homogenizing colloid mill device for reducing the viscosity of recombinant mussel mucin comprises a colloid mill body 1 and a circulation filter tank 2, wherein a feed hopper 101 is installed at the feed inlet of the colloid mill body 1, a first discharge pipe 102 is connected to the discharge port of the feed hopper 101, a circulation branch 103 is further connected to the first discharge pipe 102, a top end of the circulation branch 103 is connected to the bottom of the circulation filter tank 2, and a second discharge pipe 201 is provided at the bottom end of the circulation filter tank 2 close to the colloid mill body 1; A filter 3 is installed inside the circulation filter tank 2, and an automatic switch 4 is fixed at the bottom of the filter 3. The automatic switch 4 switches the circulation state and the filtering state by opening and closing. A suction pipe 202 is installed near the top of the circulation filter tank 2 away from the colloid mill body 1. A moving grinding disc and a static grinding disc are arranged inside the colloid mill body 1. By driving the moving grinding disc to rotate relative to the static grinding disc, a feeding screw is installed at the bottom end of the feed hopper 101. The extrusion force generated by the rotation of the feeding screw conveys the material through the gap between the moving grinding disc and the static grinding disc, so that the material is effectively emulsified, dispersed, homogenized and crushed, achieving the effect of ultra-fine crushing and emulsification of the material. First, the valve on the first discharge pipe 102 is closed, so that the material after one treatment enters the circulation filter tank 2 from the circulation branch 103; Circulation state: the material flows out directly through the second discharge pipe 201 and falls into the feed hopper 101 again, thereby being circulated again; Filtration status: the second discharge pipe 201 is blocked, the automatic opener and closer 4 is opened, the material flows upward under pressure, and is filtered through the filter 3. The filter 3 is provided with a filter screen, which can filter out materials with high emulsification and small particle size. With the suction force of the suction pump, the filtered material is extracted from the suction pipe 202 and collected. After filtration, the remaining larger particles of the material continue to be circulated and homogenized. After a period of treatment, the gap between the dynamic grinding disc and the static grinding disc is adjusted to be smaller, and a more refined homogenization process is performed. This treatment method can specifically treat the materials with larger particles in the early stage, save more energy, and improve the treatment effect. Example 2

[0021] Reference Figure 1-12 The difference between this embodiment and the first embodiment is that the filter 3 is movably installed in the circulation filter tank 2, and an arc-shaped lifting bar 5 is movably installed on the side wall of the circulation filter tank 2 close to the second discharge pipe 201. A notch is provided on the filter 3 and the automatic shutter 4 for the arc-shaped lifting bar 5 to pass through, and an arc-shaped blocking plate 505 is elastically installed at the bottom end of the arc-shaped lifting bar 5; The arc-shaped lifting bar 5 can be lifted and lowered to drive the arc-shaped sealing plate 505 to open and block the second discharge pipe 201. In the circulation state, the second discharge pipe 201 is opened and the automatic shutter 4 is closed. In the filtering state, the second discharge pipe 201 is closed and the automatic shutter 4 is opened.

[0022] Among them, a guide column 504 is fixed to the bottom end of the arc-shaped lifting strip 5, and the guide column 504 movably penetrates the arc-shaped sealing plate 505, and a first return spring 506 is installed on the outside of the guide column 504. When, due to the existence of the first return spring 506, when the arc-shaped sealing plate 505 moves downward and contacts the inner wall of the bottom end of the circulation filter tank 2, the arc-shaped lifting strip 5 continues to move downward, and the first return spring 506 will be compressed, so that the second discharge pipe 201 can be blocked in the first time. When the arc-shaped lifting strip 5 moves upward, due to the elastic force of the first return spring 506, the arc-shaped lifting strip 5 will be kept at the lowest position and the second discharge pipe 201 will be blocked, thereby achieving the purpose of quickly blocking the second discharge pipe 201 and delaying the opening of the second discharge pipe 201.

[0023] Among them, a first threaded tube 501 is fixed to the top of the arc-shaped lifting strip 5, a second threaded tube 302 is fixed to the top of the filter 3, a first threaded rod 203 and a second threaded rod 204 are rotatably installed in the circulation filter tank 2, the first threaded tube 501 and the second threaded tube 302 are respectively threadedly installed on the outside of the first threaded rod 203 and the second threaded rod 204, the tops of the first threaded rod 203 and the second threaded rod 204 extend to the outside of the circulation filter tank 2 and are respectively fixed with a first spur gear 206 and a second spur gear 205, a rotating motor 207 is fixed to the top of the circulation filter tank 2, and a third spur gear 208 is fixed to the output shaft of the rotating motor 207, the first spur gear 206 and the second spur gear 205 are respectively meshed with the third spur gear 208 from both sides of the third spur gear 208, and the diameter of the first spur gear 206 is smaller than the diameter of the second spur gear 205; When the rotating motor 207 is turned on, the rotating motor 207 will drive the third spur gear 208, and the third spur gear 208 can drive the first spur gear 206 and the second spur gear 205 to rotate. Since the diameter of the first spur gear 206 is smaller than the diameter of the second spur gear 205, the rotation speed of the first threaded rod 203 is greater than the rotation speed of the second threaded rod 204. Driven by the first threaded rod 203 and the second threaded rod 204, the arc lifting bar 5 and the filter 3 are lifted and moved, and the moving speed of the arc lifting bar 5 is greater than the moving speed of the filter 3. Therefore, relative displacement will also occur between the arc lifting bar 5 and the filter 3. Since the filter 3 moves more slowly, when moving downward, the second discharge pipe 201 will be quickly blocked by the arc blocking plate 505. At this time, as the filter 3 continues to press down and compress the front lower space, the material will be forced to pass through the filter 3 at an accelerated speed due to the pressure, thereby improving the filtering efficiency.

[0024] Due to the relative displacement between the arc-shaped lifting bar 5 and the filter 3, a vertical rotating shaft 6 is rotatably installed at the center position of the filter 3, the bottom end of the vertical rotating shaft 6 extends to the bottom of the filter 3 and is fixed with a plurality of scrapers 606, the top end of the vertical rotating shaft 6 extends to the top of the filter 3 and is fixed with a first bevel gear 601 on the outside, and a transmission horizontal shaft 602 is also rotatably installed above the filter 3, a second bevel gear 603 is fixed to one end of the transmission horizontal shaft 602 close to the vertical rotating shaft 6, the second bevel gear 603 is meshed with the first bevel gear 601, a fourth spur gear 604 is fixed to one end of the transmission horizontal shaft 6 away from the vertical rotating shaft 6, a vertical groove 502 is provided on one side of the arc-shaped lifting bar 5 close to the vertical rotating shaft 6, a first rack 503 is fixed on the side wall of the vertical groove 502, and the fourth spur gear 604 is meshed with the first rack 503; The first rack 503 will move up and down relative to the fourth spur gear 604, thereby driving the transmission horizontal shaft 602 to rotate through engagement, and then the second bevel gear 603 and the first bevel gear 601 are engaged to drive the vertical shaft 6 to rotate, thereby driving the scraper 606 to clean the filtered material accumulated at the bottom of the filter 3, thereby improving the filtering efficiency. Example 3

[0025] Reference Figure 1-12 The difference between this embodiment and embodiment 6 is that a vertical baffle 605 is rotatably installed outside the transmission horizontal shaft 602, and the vertical baffle 605 is movably installed in the vertical groove 502; Since the vertical baffle 605 is stuck in the vertical groove 502, and the arc-shaped lifting bar 5 is stuck in the gaps on the filter 3 and the automatic opener 4, when the filter 3 and the arc-shaped lifting bar 5 are relatively positioned, no large gap will be generated, so that the material will only pass through the filter net 301 on the filter 3.

[0026] The vertical rotating shaft 6 is hollow inside, and a lifting vertical shaft 7 is movably installed inside the vertical rotating shaft 6, a second reset spring 702 is installed on the outer side of the lifting vertical shaft 7, a plurality of fan-shaped openings are opened on the automatic shutter 4, a fan-shaped blocking plate 401 is rotatably installed inside the fan-shaped opening, a fifth spur gear 402 is fixed on the mounting rotating shaft of the fan-shaped blocking plate 401, a plurality of second racks 703 are fixed on the bottom end of the lifting vertical shaft 7, each second rack 703 is respectively meshed with a fifth spur gear 402, a disc 701 is fixed on the top end of the lifting vertical shaft 7, a trigger rod 209 is fixed on the inner wall of the top end of the circulation filter tank 2, and the trigger rod 209 corresponds to the disc 701; When the second return spring 702 is in a natural state, the lifting vertical shaft 7 is pushed upward and is at the highest point. In this state, the fan-shaped blocking plate 401 is in a vertical state and the fan-shaped opening is opened. When the filter 3 moves upward, the trigger rod 209 hits the disc 701, which will overcome the elastic force of the second return spring 702 to press down the lifting vertical shaft 7, and drive the second rack 703 to move downward, and then drive the fan-shaped blocking plate 401 to flip ninety degrees through the engagement of the second rack 703 and the fifth spur gear 402, thereby blocking the fan-shaped opening. Therefore, the fan-shaped opening is blocked when the filter 3 is in the highest position, and when the filter 3 moves downward, the fan-shaped opening will quickly open automatically, thereby achieving the purpose of automatic opening and closing.

[0027] One end of the suction pipe 202 extends to the inside of the circulation filter tank 2 and vertically extends downward, and a telescopic pipe 2021 is vertically movably installed inside the circulation filter tank 2, and the bottom end of the telescopic pipe 2021 is fixedly connected to the filter 3; When the filter 3 moves downward, the telescopic tube 2021 will move downward accordingly, thereby preventing the occurrence of empty suction.

[0028] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0029] In the present invention, unless otherwise clearly specified and limited, the terms "set", "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0030] The control method of the present invention is automatic control through a controller. The control circuit of the controller can be implemented by simple programming by technicians in this field. The provision of power is also common knowledge in this field. The present invention is mainly used to protect mechanical devices, so the present invention will no longer explain the control method and circuit connection in detail.

[0031] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin, characterized in that: The invention comprises a colloid mill body (1) and a circulation filter tank (2), wherein a feed hopper (101) is installed at the feed inlet of the colloid mill body (1), a first discharge pipe (102) is connected to the discharge port of the feed hopper (101), a circulation branch (103) is also connected to the first discharge pipe (102), the top end of the circulation branch (103) is connected to the bottom of the circulation filter tank (2), and a second discharge pipe (201) is provided at the bottom end of one side of the circulation filter tank (2) close to the colloid mill body (1); A filter (3) is installed inside the circulation filter tank (2), and an automatic switch (4) is fixed to the bottom end of the filter (3). The automatic switch (4) switches the circulation state and the filtering state by opening and closing. A suction pipe (202) is installed near the top end of the circulation filter tank (2) away from the colloid mill body (1).

2. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 1, characterized in that: The filter (3) is movably mounted inside the circulation filter tank (2) in a lifting manner; an arc-shaped lifting bar (5) is movably mounted on a side wall of the circulation filter tank (2) close to the second discharge pipe (201); a notch is provided on the filter (3) and the automatic shutter (4) for the arc-shaped lifting bar (5) to pass through; and an arc-shaped blocking plate (505) is elastically mounted on the bottom end of the arc-shaped lifting bar (5).

3. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 2, characterized in that: A guide column (504) is fixed to the bottom end of the arc-shaped lifting strip (5), the guide column (504) movably penetrates the arc-shaped blocking plate (505), and a first return spring (506) is installed outside the guide column (504).

4. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 2, characterized in that: A first threaded tube (501) is fixed to the top of the arc-shaped lifting strip (5), a second threaded tube (302) is fixed to the top of the filter (3), a first threaded rod (203) and a second threaded rod (204) are rotatably mounted in the circulation filter tank (2), and the first threaded tube (501) and the second threaded tube (302) are respectively threadedly mounted on the outside of the first threaded rod (203) and the second threaded rod (204).

5. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 4, characterized in that: The top ends of the first threaded rod (203) and the second threaded rod (204) both extend to the outside of the circulation filter tank (2) and are respectively fixed with a first spur gear (206) and a second spur gear (205).

6. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 5, characterized in that: A rotating motor (207) is fixedly mounted on the top of the circulating filter tank (2); a third spur gear (208) is fixedly mounted on the output shaft of the rotating motor (207); the first spur gear (206) and the second spur gear (205) are respectively meshed with the third spur gear (208) from both sides of the third spur gear (208); and the diameter of the first spur gear (206) is smaller than the diameter of the second spur gear (205).

7. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 6, characterized in that: A vertical rotating shaft (6) is rotatably mounted at the center of the filter (3); the bottom end of the vertical rotating shaft (6) extends to the bottom of the filter (3) and is fixed with a plurality of scrapers (606); the top end of the vertical rotating shaft (6) extends to the top of the filter (3) and is fixed with a first bevel gear (601) on the outside; a transmission horizontal shaft (602) is also rotatably mounted above the filter (3); a second bevel gear (603) is fixed to one end of the transmission horizontal shaft (602) close to the vertical rotating shaft (6); the second bevel gear (603) meshes with the first bevel gear (601); a fourth spur gear (604) is fixed to one end of the transmission horizontal shaft (602) away from the vertical rotating shaft (6); a vertical groove (502) is provided on one side of the arc-shaped lifting bar (5) close to the vertical rotating shaft (6); a first rack (503) is fixed to the side wall of the vertical groove (502); the fourth spur gear (604) meshes with the first rack (503).

8. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 7, characterized in that: A vertical baffle (605) is rotatably mounted on the outside of the transmission horizontal shaft (602), and the vertical baffle (605) is movably mounted in the vertical groove (502) in a lifting manner.

9. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 7, characterized in that: The vertical rotating shaft (6) is hollow inside, and a lifting vertical shaft (7) is movably installed inside the vertical rotating shaft (6), a second reset spring (702) is installed on the outer side of the lifting vertical shaft (7), a plurality of fan-shaped openings are opened on the automatic shutter (4), a fan-shaped blocking plate (401) is rotatably installed in the fan-shaped opening, a fifth spur gear (402) is fixed on the mounting rotating shaft of the fan-shaped blocking plate (401), a plurality of second racks (703) are fixed on the bottom end of the lifting vertical shaft (7), each second rack (703) is respectively meshed with a fifth spur gear (402), a disc (701) is fixed on the top end of the lifting vertical shaft (7), a trigger rod (209) is fixed on the inner wall of the top end of the circulation filter tank (2), and the trigger rod (209) corresponds to the disc (701).

10. A homogenizing colloid mill for reducing the viscosity of recombinant mussel mucin according to claim 2, characterized in that: One end of the suction pipe (202) extends to the interior of the circulation filter tank (2) and extends vertically downward, and a telescopic pipe (2021) is vertically movably installed inside the circulation filter tank (2), and the bottom end of the telescopic pipe (2021) is fixedly connected to the filter (3).

Images