Mycobacterium tuberculosis collection and pretreatment device based on tongue swab specimen

Abstract

The invention belongs to the field of mycobacterium tuberculosis detection, and particularly relates to a mycobacterium tuberculosis collection and pretreatment device based on a tongue swab specimen, the mycobacterium tuberculosis collection and pretreatment device comprises a sampling tube, a sealing cover and a sampling swab, the sampling tube is in threaded connection with the sealing cover, the sampling swab is arranged in the middle of the sealing cover and extends into the sampling tube, and the sampling swab is arranged in the sealing cover. An injection mechanism is arranged in the sealing cover, a culture solution is stored in the injection mechanism, the sampling swab comprises a vertical rod and a sampling plate, the vertical rod is a hollow mechanism and is communicated with the injection mechanism, and the sampling plate is arranged at the sampling end of the vertical rod. According to the invention, collection and pretreatment of the mycobacterium tuberculosis tongue swab sample can be realized, and the sampling rate of the sample is improved.

Description

Technical Field

[0001] The invention belongs to the field of Mycobacterium tuberculosis detection, and in particular relates to a Mycobacterium tuberculosis collection and pre-treatment device based on tongue swab specimens. Background Art

[0002] Tongue swab is a sampling method for Mycobacterium tuberculosis testing. When collecting specimens, the patient is required to open his mouth and expose the oral cavity so that medical staff or inspectors can use a cotton swab to lightly wipe the surface of the patient's tongue to obtain secretions, and store the secretions in a sealed sampling tube for later testing.

[0003] However, there is no special tongue swab device for collecting and pre-processing Mycobacterium tuberculosis. The purpose of pre-processing is mainly twofold: (1) removing bacteria other than mycobacteria (decontamination); (2) liquefying specimens for easy detection. Chinese utility model patent CN217006494U discloses an auxiliary device suitable for sputum specimen collection and pre-processing, which can only perform pre-processing of sputum specimens, but is not suitable for the collection of tongue surface samples. Since the collection of tongue surface specimens requires the consideration of collecting multiple parts of the tongue surface to increase the sampling rate, the sampling capacity of conventional cotton swabs is limited, and it is impossible to perform pre-processing of tongue surface samples.

[0004] Therefore, how to provide a Mycobacterium tuberculosis collection and pretreatment device based on tongue swab specimens has become an issue that technicians in this field need to consider. Summary of the invention

[0005] In view of the problems mentioned in the background technology, the present invention discloses a Mycobacterium tuberculosis collection and pretreatment device based on a tongue swab specimen. The present invention increases the sampling area of ​​the swab by setting a sampling plate, realizes the pretreatment of the specimen by connecting the sampling swab to an injection mechanism, and specifically discloses the following technical solutions:

[0006] A tuberculosis Mycobacterium collection and pretreatment device based on tongue swab specimens comprises a sampling tube, a sealing cover and a sampling swab, wherein the sampling tube is threadedly connected to the sealing cover, the sampling swab is arranged in the middle of the sealing cover and extends into the sampling tube, an injection mechanism is arranged in the sealing cover, and culture fluid is stored in the injection mechanism, the sampling swab comprises a vertical rod and a sampling plate, the vertical rod is a hollow mechanism and is connected to the injection mechanism, and the sampling plate is arranged at the sampling end of the vertical rod.

[0007] Furthermore, the sampling plate is rectangular, a connecting pipe is provided in the middle of the sampling plate, the connecting pipe is sleeved on the vertical rod, and a rubber anti-slip layer is provided inside the connecting pipe.

[0008] Furthermore, a partition is provided in the middle of the sampling tube, a through hole is provided in the middle of the partition corresponding to the vertical rod, and transverse holes for the sampling plate to pass through are provided on both sides of the through hole.

[0009] Furthermore, a protective protrusion is provided on the top of the sampling plate.

[0010] Furthermore, both sides of the sampling plate are provided with fluff inclined toward the sealing cover.

[0011] Furthermore, the injection mechanism includes a liquid capsule and a push switch, the liquid capsule is arranged in the sealing cover, the push switch is arranged at the top of the liquid capsule, a slide groove is arranged on one side of the sealing cover, and the push switch is confined in the slide groove.

[0012] Furthermore, a rubber film for sealing is provided at the end of the vertical rod.

[0013] Furthermore, a conical protrusion is provided at the bottom end of the sampling tube corresponding to the rubber film.

[0014] Furthermore, the top of the conical protrusion is hollow, and the bottom of the conical protrusion is provided with a liquid outlet hole connected with the top of the conical protrusion.

[0015] The beneficial effects of the present invention are as follows: the present invention adopts a structural design in which the sealing cover and the sampling swab are integrated, occupies a small space, can separate and protect the sampling plate and the culture fluid to avoid contamination, and by arranging an injection mechanism in the sealing cover, the pretreatment of Mycobacterium tuberculosis can be achieved through the injection mechanism, and the treated culture fluid can be collected after standing. The sampling plate adopts a double-sided rectangular structure design, which increases the sampling area and can quickly collect samples on the surface of the tongue. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the main body of the present invention;

[0017] Figure 2 This is a schematic diagram of the sealing cover and sampling swab structure of the present invention;

[0018] Figure 3 It is a cross-sectional view of the present invention;

[0019] Figure 4 for Figure 3 A partial enlarged view of the middle part;

[0020] Figure 5 This is a schematic diagram of the partition structure of the present invention;

[0021] Figure 6 It is a schematic diagram of the conical protrusion structure of the present invention;

[0022] Figure 7 It is a side view of the sampling plate of the present invention;

[0023] Figure 8 for Figure 7 A partial enlarged view of point B in the middle;

[0024] Fig. 9 It is a cross-sectional view of the sealing cover in Example 2 of the present invention;

[0025] Fig.10 for Fig. 9 A partial enlarged view of point C in the middle;

[0026] Fig.11 This is a schematic diagram of the card block structure in Example 2 of the present invention.

[0027] Among them, 1-sampling tube; 2-sealing cover; 3-vertical rod; 4-sampling plate; 5-partition; 6-protective protrusion; 7-liquid bag; 8-push switch; 9-conical protrusion; 10-liquid outlet; 11-elastic telescopic rod; 12-clamping groove; 13-clamping block; 14-fluff. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] Example 1

[0030] like Figure 1-8 As shown, this embodiment discloses a Mycobacterium tuberculosis collection and pretreatment device based on a tongue swab specimen, comprising a sampling tube 1, a sealing cover 2 and a sampling swab, wherein the sampling tube 1 is threadedly connected to the sealing cover 2, the sampling swab is arranged in the middle part of the sealing cover 2 and extends into the sampling tube 1, an injection mechanism is arranged in the sealing cover 2, a culture fluid is stored in the injection mechanism, and the culture fluid can be 4% NaoH digestion fluid or NALC-NaOH solution, the sampling swab comprises a vertical rod 3 and a sampling plate 4, the vertical rod 3 is a hollow mechanism and is connected to the injection mechanism, and the sampling plate 4 is arranged at the sampling end of the vertical rod 3.

[0031] In order to facilitate the fixation of the sampling swab, a partition 5 is arranged in the middle of the sampling tube 1, and a through hole is arranged in the middle of the partition 5 corresponding to the vertical rod 3, and transverse holes for the sampling plate 4 to pass through are arranged on both sides of the through hole. The setting of the partition 5 improves the fixing effect of the sampling swab in the sampling tube 1, avoids the sampling plate 4 from touching the tube wall, resulting in the sampled specimen remaining on the tube wall, and the residual specimen is difficult to be infiltrated by the culture fluid, which has a certain safety risk; and after the sample is left to stand, the partition 5 can be clamped on the sampling plate 4 by rotating and pulling up, so that the sampling plate 4 can be removed from the vertical rod 3.

[0032] Specifically, the sampling plate 4 is rectangular, a connecting tube is provided in the middle of the sampling plate 4, a rubber anti-skid layer is provided in the connecting tube, the sampling plate 4 is sleeved on the vertical rod 3 through the connecting tube, and the setting of the rubber anti-skid layer prevents the sampling plate 4 and the vertical rod 3 from easily sliding relative to each other; both sides of the sampling plate 4 are provided with fluff 14 inclined toward the sealing cover 2, and when sampling, the tongue is scraped from the inside to the outside, and samples can be taken from both sides of the sampling plate 4, thereby improving the sampling rate; the top of the sampling plate 4 is provided with an oblique protective protrusion 6, so that when the sampling plate 4 passes through the partition 5, it can well prevent the sample on the surface of the sampling plate 4 from touching the partition 5 after sampling.

[0033] As a preferred embodiment of the present invention, the injection mechanism includes a liquid capsule 7 and a push switch 8. The liquid capsule 7 is arranged in the sealing cover 2. The liquid capsule 7 in this embodiment is an inverted corrugated soft rubber bottle structure. The push switch 8 is arranged at the top of the liquid capsule 7. A slide groove is arranged on one side of the sealing cover 2, and the push switch 8 is confined in the slide groove.

[0034] As a preferred embodiment of the present invention, a rubber film for sealing is provided at the end of the vertical rod 3, and a conical protrusion 9 is provided at the bottom end of the sampling tube 1 corresponding to the rubber film. Specifically, the top of the conical protrusion 9 is hollow, and the bottom of the conical protrusion 9 is provided with a liquid outlet 10 connected to the top of the conical protrusion 9.

[0035] The sampling swab in this embodiment is usually stored in the sampling tube 1, and the mouth of the sampling tube 1 is sealed by the sealing cover 2 to avoid contamination. At this time, the rubber film just cannot touch the conical protrusion 9, and the culture fluid is sealed in the liquid capsule 7. When sampling is needed, only the sampling swab needs to be taken out, and the medical staff wipes the surface of the patient's tongue from the inside to the outside for sampling. After sampling, the sampling swab is placed in the sampling tube 1, and the push switch 8 is toggled downward to make the bottom rubber film bulge and touch the conical protrusion 9. The rubber film is punctured, and the culture fluid flows into the sampling tube 1 as the push switch 8 moves downward until the sampling plate 4 is immersed. The sealing cover 2 is tightened to form a sealed environment. After standing and mixing for a period of time, the sealing cover 2 is loosened, and the push switch 8 is pushed upward to suck the mixed culture fluid into the liquid capsule 7 through the hollow vertical rod 3. The vertical rod 3 is pulled upward and rotated to a certain angle. The partition 5 can be used to remove the sampling plate 4 from the vertical rod 3, so that the vertical rod 3 can inject the mixed culture fluid into other test tubes.

[0036] Example 2

[0037] like Figure 9-11As shown, the difference between this embodiment and embodiment 1 is that, in this embodiment, the inner side of the push switch 8 is connected to an elastic telescopic rod 11, and the push switch 8 is installed at the end of the piston rod of the elastic telescopic rod 11. In order to realize the locking of the position of the liquid capsule 7 at any time, the inner side surface of the sealing cover 2 is evenly provided with a clamping groove 12 in the longitudinal direction, and a clamping block 13 is correspondingly provided on the piston rod of the ejection telescopic rod 11. Under normal conditions, the clamping block is locked in the clamping groove 12 under the push of the piston rod of the elastic telescopic rod 11, so that the liquid capsule 7 cannot move. When the culture solution needs to be pushed out, the push switch 8 is pressed inward, and the clamping block 13 is disengaged from the clamping groove at the same time. Then the push switch 8 is toggled downward to push the culture solution into the sampling tube 1.

[0038] The above description is only a preferred embodiment of the present invention and does not limit the technical scope of the present invention. Therefore, any slight modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens, characterized in that: It includes a sampling tube, a sealing cover and a sampling swab. The sampling tube is threadedly connected to the sealing cover. The sampling swab is arranged in the middle of the sealing cover and extends into the sampling tube. An injection mechanism is arranged in the sealing cover. Culture fluid is stored in the injection mechanism. The sampling swab includes a vertical rod and a sampling plate. The vertical rod is a hollow mechanism and is connected to the injection mechanism. The sampling plate is arranged at the sampling end of the vertical rod.

2. A Mycobacterium tuberculosis collection and pretreatment device based on tongue swab specimens according to claim 1, characterized in that: The sampling plate is rectangular, a connecting pipe is arranged in the middle of the sampling plate, the connecting pipe is sleeved on the vertical rod, and a rubber anti-slip layer is arranged inside the connecting pipe.

3. The device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens according to claim 1, characterized in that: A partition is arranged in the middle of the sampling tube, a through hole is arranged in the middle of the partition corresponding to the vertical rod, and transverse holes for the sampling plate to pass through are arranged on both sides of the through hole.

4. The device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens according to claim 1, characterized in that: A protective protrusion is arranged on the top of the sampling plate.

5. The Mycobacterium tuberculosis collection and pre-treatment device based on tongue swab specimens according to claim 1, characterized in that: Both sides of the sampling plate are provided with fluff inclined toward the sealing cover.

6. The Mycobacterium tuberculosis collection and pretreatment device based on tongue swab specimens according to claim 1, characterized in that: The injection mechanism comprises a liquid capsule and a push switch, wherein the liquid capsule is arranged in a sealing cover, the push switch is arranged at the top of the liquid capsule, a slide groove is arranged on one side of the sealing cover, and the push switch is confined in the slide groove.

7. The device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens according to claim 1, characterized in that: The end of the vertical rod is provided with a rubber film for sealing.

8. The Mycobacterium tuberculosis collection and pre-treatment device based on tongue swab specimens according to claim 7, characterized in that: The bottom end of the sampling tube is provided with a conical protrusion corresponding to the rubber film.

9. The device for collecting and pre-processing Mycobacterium tuberculosis based on tongue swab specimens according to claim 8, characterized in that: The top of the conical protrusion is hollow, and the bottom of the conical protrusion is provided with a liquid outlet hole connected with the top of the conical protrusion.

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