Rose essential oil aromatic composition and application thereof

Abstract

The invention provides a rose essential oil aromatic composition and application thereof, and belongs to the technical field of plant essential oil. The rose essential oil aromatic composition comprises rose essential oil, rosemary essential oil and meadowfoam seed oil, and has the characteristics of aromatic smell and simple proportion; and the three plant essential oils are compounded to play a synergistic effect, so that the plant essential oil has excellent effects of resisting and inhibiting bacteria, resisting inflammation, relieving and assisting sleep. The composition can be applied to formulas of daily chemical products for hair and daily chemical products for skin, and has the effects of effectively resisting bacteria, resisting inflammation and nourishing, so that the micro-ecological balance of scalp and skin is regulated; meanwhile, the smell is fragrant, and the effects of pacifying emotion and assisting sleep can be achieved.

Description

Technical Field

[0001] The invention belongs to the technical field of plant essential oils, and in particular relates to a rose essential oil aromatic composition and application thereof. Background Art

[0002] Plant essential oils are volatile or non-volatile oil components extracted from the flowers, leaves, seeds, peels, rhizomes and other parts of plants by various technical methods such as steam distillation, pressing, solvent extraction, CO2 supercritical extraction, etc. Due to its natural source, it is widely considered to be more natural, environmentally friendly, green and safer than synthetic flavors. Plant essential oils are complex mixtures of various chemical components, such as terpenes, phenols, alcohols, esters, etc. These chemical components work synergistically to give plant essential oils multiple functions such as antibacterial, anti-inflammatory, and antioxidant.

[0003] As modern people are under increasing pressure from life and work, and are affected by external factors such as irregular lifestyles, more and more negative emotions are amplified, which seriously affects their inner mood and causes insomnia. Sleep problems also have a great impact on health. Insomnia not only reduces people's attention and memory, but may also affect the body's endocrine and immune functions. Severe insomnia is usually treated with oral or injected prescription hypnotic drugs, which have many side effects and also impose additional psychological burdens on patients. Therefore, it is of great significance to provide methods and products for treating insomnia that can reduce toxic side effects. Summary of the invention

[0004] In view of the defects in the prior art, the purpose of the present invention is to provide a rose essential oil aromatic composition, which can play an antibacterial and anti-inflammatory role and thus regulate the balance of skin microecology; at the same time, its fragrant smell can also help soothe emotions, promote sleep, and is safe and has no toxic side effects.

[0005] The objective of the present invention is achieved through the following technical solutions:

[0006] The invention provides a rose essential oil aromatic composition, comprising rose essential oil, rosemary essential oil and meadowfoam seed oil.

[0007] Preferably, in parts by mass, the mass ratio of rose essential oil, rosemary essential oil and meadowfoam seed oil in the rose essential oil fragrance composition is (1-6):(1-3):(10-30).

[0008] The rose essential oil fragrance composition comprises, by weight:

[0009] 1-6 parts of rose essential oil, 1-3 parts of rosemary essential oil and 10-30 parts of meadowfoam seed oil.

[0010] Preferably, the rose essential oil includes one or more of rose flower oil, rose flower oil, damask rose flower oil, French rose flower oil and centifolia rose flower oil; the rosemary essential oil includes rosemary leaf oil.

[0011] The present invention provides a method for preparing the rose essential oil aromatic composition described in the above technical solution, comprising the following steps:

[0012] Rose essential oil, rosemary essential oil and meadowfoam seed oil are mixed according to parts by mass.

[0013] The present invention provides application of the rose essential oil fragrance composition described in the above technical scheme or the rose essential oil fragrance composition prepared by the preparation method described in the above technical scheme in the preparation of anti-inflammatory and soothing daily chemical products.

[0014] The present invention provides application of the rose essential oil fragrance composition described in the above technical scheme or the rose essential oil fragrance composition prepared by the preparation method described in the above technical scheme in the preparation of antibacterial daily chemical products.

[0015] The present invention provides application of the rose essential oil fragrance composition described in the above technical scheme or the rose essential oil fragrance composition prepared by the preparation method described in the above technical scheme in preparing a sleep-aiding daily chemical product.

[0016] The invention provides a shampoo, comprising the rose essential oil fragrance composition described in the above technical scheme or the rose essential oil fragrance composition prepared by the preparation method described in the above technical scheme.

[0017] Preferably, the shampoo further comprises the following components in mass percentage: 8-20% surfactant, 0-5% hair conditioner, 0-1% antidandruff agent, 0-1% preservative, 0-2% sodium chloride, 0-2% pH adjuster, 0-2% rheology modifier, 0-2% fragrance and water.

[0018] Preferably, the shampoo further comprises: cationic polymer, disodium EDTA, surfactant, C10-30 alkyl acrylate crosspolymer, salicylic acid, polyethylene glycol, potassium hydroxide, PEG-7M, dimethicone, ethylhexylglycerin, phenoxyethanol, fragrance and sodium chloride.

[0019] The present invention provides a method for preparing the shampoo described in the above technical solution, comprising the following steps:

[0020] The cationic polymer is used as phase A;

[0021] Disodium EDTA and surfactant are used as phase B;

[0022] The aqueous phase obtained by mixing C10-30 alkyl acrylate cross-linked polymer with water is used as phase C;

[0023] Mix salicylic acid and polyethylene glycol to obtain phase D;

[0024] Mix potassium hydroxide and water to obtain a potassium hydroxide solution as phase E;

[0025] The fragrance composition of PEG-7M, dimethicone, ethylhexylglycerin, phenoxyethanol, perfume, sodium chloride and rose essential oil is used as phase F;

[0026] Dispersing phase A in cold water and performing swelling treatment to obtain swollen phase A;

[0027] After mixing the swollen phase A with phase B, mix with phase C and phase D, then add phase E, and finally add phase F to obtain shampoo.

[0028] Beneficial effects of the present invention:

[0029] The present invention provides a rose essential oil aromatic composition, comprising: rose essential oil, rosemary essential oil and white meadowfoam seed oil. In the rose essential oil aromatic composition provided by the present invention, rose essential oil and rosemary essential oil are volatile oils, white meadowfoam seed oil is a non-volatile oil, and white meadowfoam seed oil can be used as a base oil to be miscible with rose essential oil and rosemary essential oil, thereby reducing the volatilization of rose essential oil and rosemary essential oil and contributing to the stability of effective ingredients. In traditional Chinese medicine theory, Chinese medicinal materials are usually classified according to four qi and five flavors, rising and falling, and meridians. Among them, aromatic drugs mainly have the effects of pungent fragrance, refreshing the mind, and guiding the medicine upward. The present invention proportions three kinds of plant aromatic oils, which follows the guidance of traditional Chinese medicine theory. The rose essential oil aromatic composition provided by the present invention has the effect of "spicy fragrance", the rose essential oil aromatic composition is absorbed quickly, metabolized quickly, its effective ingredients are easy to penetrate the blood-brain barrier, and has the effect of bidirectionally regulating the permeability of the blood-brain barrier; it has the effect of "awakening the mind", is good at floating and passing through the brain, reaches the brain through the olfactory pathway, and plays a role in bidirectional regulation of the central nervous system to wake up the brain and protect the brain and calm the mind; it has the effect of "leading the medicine upward", can enter the brain tissue to play a role, and can also promote other drugs to pass through the blood-brain barrier, and play a faster and better drug effect. The rose essential oil aromatic composition provided by the present invention has a simple ratio and a fragrant smell; after the three kinds of plant essential oils are compounded, a synergistic effect is exerted, and an excellent inhibitory effect is exerted on Malassezia; it has an excellent anti-inflammatory effect on the zebrafish inflammation model caused by LPS; it has an obvious sleep-assisting effect on the insomnia model of pentobarbital sodium rats. The composition can be applied to the formulation of daily chemical products for hair and skin, and can effectively play the role of antibacterial and anti-inflammatory, thereby regulating the balance of skin microecology; at the same time, its fragrant smell can also play the role of soothing emotions and helping sleep.

[0030] In summary, aromatic essential oils from different plant sources, after being matched according to certain scientific basis, have unique antibacterial and anti-inflammatory effects, as well as certain effects of soothing emotions and helping sleep, but there are almost no compositions of plant aromatic essential oils on the market that can have the effect of regulating sleep while playing a role in skin care. The rose essential oil aromatic composition provided by the present invention can be used to blend different aromatic components, and act on the human body through inhalation and massage, etc., to achieve the effects of relieving mental stress and promoting physical and mental health. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0032] Figure 1 This is a statistical result diagram of the diameter of the inhibition zone of each test group in Application Example 1;

[0033] Figure 2 This is a statistical result diagram of the survival rate of zebrafish in each test group of Application Example 2;

[0034] Figure 3 This is a statistical result diagram of the heart rate ratio of zebrafish in each test group of Application Example 2;

[0035] Figure 4 This is a graph showing the effects of each test group on zebrafish yolk sac area and fluorescence intensity in Application Example 2;

[0036] Figure 5 This is a graph showing the effects of each test group in Application Example 2 on the level of IL-6 inflammatory factor in zebrafish;

[0037] Figure 6 This is a graph showing the effects of each test group in Application Example 2 on the level of TNF-α inflammatory factor in zebrafish. DETAILED DESCRIPTION

[0038] The invention provides a rose essential oil aromatic composition, comprising rose essential oil, rosemary essential oil and meadowfoam seed oil.

[0039] In the following technical schemes, unless otherwise specified, the present invention has no special limitation on the sources of the raw materials, and any conventional commercially available products in the art may be used.

[0040] As preferably, by mass, the rose essential oil aromatic composition provided by the present invention may include 1 to 6 parts of rose essential oil. In an embodiment of the present invention, the rose essential oil may be 1 part, 2 parts or 3 parts. In an embodiment of the present invention, the rose essential oil is a volatile essential oil extracted from roses with a strong fragrance. In the present invention, the rose essential oil may include any one or more of rose flower oil (ROSA SPP.), rose (ROSA RUGOSA) flower oil, Damascus rose (ROSADAMASCENA, also known as Damascus rose) flower oil, French rose (ROSA GALLICA) flower oil and rose (ROSA CENTIFOLIA, also known as Centifolia rose) flower oil. In the present invention, the main components in rose essential oil are citronellol, geraniol, β-phenylethanol, etc., which have good antibacterial and antioxidant abilities.

[0041] Preferably, based on the mass parts of rose essential oil, the rose essential oil aromatic composition provided by the present invention can include 1 to 3 parts of rosemary essential oil. In an embodiment of the present invention, the rosemary essential oil can be 1 part, 2 parts or 3 parts. In the present invention, the rosemary essential oil can include rosemary leaf oil. In an embodiment of the present invention, the rosemary essential oil can be a volatile essential oil extracted from the leaves of the evergreen shrub rosemary (ROSMARINUS OFFICINALIS) of the genus Salvia of the Labiatae family. Rosemary is an important natural spice plant, and volatile essential oil is the main part of its physiological activity. The main components in rosemary essential oil are compounds such as eucalyptol, limonene, camphor, α-pinene, β-pinene, etc., which have excellent anti-inflammatory, antibacterial, antioxidant and other effects.

[0042] As preferably, based on the mass parts of rose essential oil, the rose essential oil aromatic composition provided by the present invention can include 10 to 30 parts of white pond flower seed oil. In an embodiment of the present invention, the white pond flower seed oil can be 20 parts. In an embodiment of the present invention, white pond flower (LIMNANTHES ALBA) seed oil is a grease obtained by squeezing from the seeds of a plant of the Limnanthaceae (Limnanthaceae) native to North America. It is a non-volatile fatty grease with strong oxidative stability. It is one of the most stable vegetable oils in the world and can enhance the stability of the mixture while stabilizing itself. White pond flower seed oil is rich in monounsaturated fatty acid chains and contains vitamin A and vitamin E. White pond flower seed oil has a unique molecular structure and is mainly composed of long-chain fatty acids (C20-22), and its content accounts for more than 95% of the total fatty acids. The carbon chain length of its fatty acids is closely related to the skin barrier function. Long carbon chain fatty acids can significantly increase lipid density, help maintain the moisture retention of the skin, and enhance the skin barrier function. In addition, long-chain free fatty acids can combine with ceramides to form a highly uniform lipid structure, which is beneficial to skin barrier repair.

[0043] In the rose essential oil aromatic composition provided by the present invention, rose essential oil and rosemary essential oil are volatile oils, and white meadowfoam seed oil is a non-volatile oil, which can be used as a base oil to be miscible with the former two, reduce their volatilization and contribute to the stability of the effective ingredients. In traditional Chinese medicine theory, Chinese medicinal materials are usually classified according to four qi and five flavors, rising and falling, and meridians. Among them, aromatic drugs mainly have the effects of pungent fragrance, refreshing the mind, and guiding the medicine upward. The present invention proportions the three kinds of plant aromatic oils, just following the guidance of traditional Chinese medicine theory. The rose essential oil aromatic composition provided by the invention has the effect of "spicy fragrance running through the body", is quickly absorbed and metabolized, and its effective ingredients can easily penetrate the blood-brain barrier and has the effect of bidirectionally regulating the permeability of the blood-brain barrier; it has the effect of "awakening the mind", is good at rising and passing through the brain, reaches the brain through the olfactory pathway, and exerts the effect of bidirectionally regulating the central nervous system in terms of awakening and protecting the brain and calming and tranquilizing the mind; it has the effect of "leading drugs upward", can enter the brain tissue to exert its effect, and can also promote other drugs to penetrate the blood-brain barrier, so as to exert the drug effect faster and better.

[0044] The present invention provides a method for preparing the rose essential oil aromatic composition described in the above technical solution, comprising the following steps:

[0045] Rose essential oil, rosemary essential oil and meadowfoam seed oil are mixed according to parts by mass. The present invention has no special limitation on the mixing method, and any conventional mixing method in the art can be used.

[0046] The present invention provides the use of the rose essential oil fragrance composition described in the above technical scheme or the rose essential oil fragrance composition prepared by the preparation method described in the above technical scheme in the preparation of anti-inflammatory soothing daily chemical products. The results of the examples show that the rose essential oil fragrance composition provided by the present invention has an excellent anti-inflammatory effect on the zebrafish inflammation model caused by LPS, and can significantly reduce the increase in heart rate ratio caused by inflammatory factors; inhibit the increase in yolk sac area and the generation of ROS caused by inflammatory factors; inhibit the generation of inflammatory factors TNF-α and IL-6, thereby inhibiting the development of inflammation. Based on the anti-inflammatory effect of the rose essential oil fragrance composition, it can be used as an anti-inflammatory soothing daily chemical product. In the present invention, the anti-inflammatory soothing daily chemical product may include a hair daily chemical product and / or a skin daily chemical product.

[0047] The present invention provides the application of the rose essential oil aromatic composition described in the above technical scheme or the rose essential oil aromatic composition prepared by the preparation method described in the above technical scheme in the preparation of antibacterial daily chemical products. Preferably, the bacteria described in the present invention can include Malassezia. The results of the embodiments show that the rose essential oil aromatic composition provided by the present invention has a significant inhibitory effect on Malassezia, and then proves that the rose essential oil aromatic composition can be used to inhibit dermatophytes and play the purpose of protecting the skin. Based on the antibacterial effect of the rose essential oil aromatic composition, it can be used as an antibacterial daily chemical product. In the present invention, the antibacterial daily chemical product can include a hair daily chemical product and / or a skin daily chemical product.

[0048] The present invention provides the use of the rose essential oil aromatic composition described in the above technical solution or the rose essential oil aromatic composition prepared by the preparation method described in the above technical solution in the preparation of a sleep-aiding daily chemical product. The results of the examples show that the rose essential oil aromatic composition provided by the present invention can significantly shorten the sleep latency of rats, and can significantly prolong the sleep duration of rats, achieving the effects of soothing emotions, helping sleep, etc. Based on the sleep-aiding effect of the rose essential oil aromatic composition, it can be used as a sleep-aiding daily chemical product. In the present invention, the sleep-aiding daily chemical product can include a hair daily chemical product and / or a skin daily chemical product.

[0049] The present invention provides a shampoo, which comprises the rose essential oil fragrance composition described in the above technical solution. As an embodiment, the shampoo also comprises the following components in mass percentage: 8-20% surfactant, 0-5% hair conditioner, 0-1% antidandruff agent, 0-1% preservative, 0-2% sodium chloride, 0-2% pH adjuster, 0-2% rheology modifier, 0-2% essence and water. As an embodiment, the shampoo may also comprise: cationic polymer, disodium EDTA, surfactant solution, C10-30 alkyl acrylate cross-linked polymer, salicylic acid, polyethylene glycol, potassium hydroxide, PEG-7M, polydimethylsiloxane, ethylhexylglycerin, phenoxyethanol, essence and sodium chloride.

[0050] As an optional embodiment, the mass percentage of the rose essential oil fragrance composition in the shampoo of the present invention can be 0.5% to 5%, or can be 1.00%. The rose essential oil fragrance composition is added to the shampoo of the present invention, so that the shampoo can produce a fresh fragrance, which makes people feel comfortable; the fragrance can make people happy and help sleep; after washing hair with the shampoo, the scalp feels comfortable, making the scalp and hair healthier.

[0051] As an optional embodiment, the mass percentage of the cationic polymer in the shampoo of the present invention can be 0.40%. In an embodiment of the present invention, the cationic polymer can include hydroxypropyl guar trimethyl ammonium chloride and polyquaternium-10; the mass ratio of hydroxypropyl guar trimethyl ammonium chloride to polyquaternium-10 can be 3:1.

[0052] Preferably, the mass percentage of the disodium EDTA in the shampoo of the present invention may be 0.10%.

[0053] Preferably, the mass percentage of the surfactant solution in the shampoo of the present invention can be 26.40%. In the present invention, the surfactant in the shampoo can include cocamidopropyl betaine, sodium laureth sulfate, ammonium lauryl sulfate, ethylene glycol distearate, cetearyl alcohol and niacinamide. In the present invention, some of the raw materials in the surfactant are added in the form of a solution in the preparation of the shampoo, so the amount of the surfactant in the shampoo is expressed as the amount of the surfactant solution. In the present invention, the cocamidopropyl betaine is preferably added in the form of a cocamidopropyl betaine aqueous solution; the volume concentration of cocamidopropyl betaine in the cocamidopropyl betaine aqueous solution can be 30%. In the present invention, the sodium laureth sulfate is preferably added in the form of a sodium laureth sulfate aqueous solution; the volume concentration of the sodium laureth sulfate aqueous solution can be 70%. In the present invention, the ammonium lauryl sulfate is preferably added in the form of an aqueous solution of ammonium lauryl sulfate, and the volume concentration of ammonium lauryl sulfate in the aqueous solution of ammonium lauryl sulfate can be 70%. In the present invention, the mass percentage of the aqueous solution of cocamidopropyl betaine in the shampoo can be 4.00%; the mass percentage of the aqueous solution of sodium laureth sulfate in the shampoo can be 16.00%; the mass percentage of the aqueous solution of ammonium lauryl sulfate in the shampoo can be 3.00%; the mass percentage of ethylene glycol distearate in the shampoo can be 2.00%; the mass percentage of cetearyl alcohol in the shampoo can be 0.40%; and the mass percentage of niacinamide in the shampoo can be 1.00%.

[0054] As an optional embodiment, the C10-30 alkyl acrylate cross-linked polymer in the shampoo of the present invention is preferably added in the form of a C10-30 alkyl acrylate cross-linked polymer aqueous phase; the C10-30 alkyl acrylate cross-linked polymer aqueous phase is preferably obtained by mixing the C10-30 alkyl acrylate cross-linked polymer and water in a mass ratio of 0.4:20. In the present invention, the mass percentage of the C10-30 alkyl acrylate cross-linked polymer aqueous phase in the shampoo can be 20.40%.

[0055] Preferably, the mass percentage of salicylic acid in the shampoo of the present invention may be 0.50%.

[0056] Preferably, the mass percentage of the polyethylene glycol in the shampoo of the present invention may be 1.00%.

[0057] Preferably, the potassium hydroxide in the shampoo of the present invention can be added in the form of a potassium hydroxide aqueous solution; the mass concentration of potassium hydroxide in the potassium hydroxide aqueous solution can be 25%. Preferably, the mass percentage of the potassium hydroxide aqueous solution in the shampoo of the present invention can be 0.80%.

[0058] Preferably, the PEG-7M in the shampoo of the present invention can be added in the form of a PEG-7M aqueous solution; the mass concentration of PEG-7M in the PEG-7M aqueous solution can be 5.0%. Preferably, the mass percentage of the PEG-7M aqueous solution in the shampoo of the present invention can be 0.60%.

[0059] Preferably, the mass percentage of the polydimethylsiloxane in the shampoo of the present invention may be 2.00%.

[0060] Preferably, the mass percentage of ethylhexylglycerin in the shampoo of the present invention may be 0.30%.

[0061] Preferably, the mass percentage of phenoxyethanol in the shampoo of the present invention may be 0.60%.

[0062] Preferably, the mass percentage of the fragrance in the shampoo of the present invention may be 0.30%.

[0063] Preferably, the mass percentage of the sodium chloride in the shampoo of the present invention may be 1.40%.

[0064] Preferably, the shampoo of the present invention comprises a balance of water. The present invention has no particular limitation on the source of water, and any conventional water in the art may be used.

[0065] The present invention also provides a method for preparing the shampoo described in the above technical solution, comprising the following steps:

[0066] The cationic polymer is used as phase A;

[0067] Disodium EDTA and surfactant are used as phase B;

[0068] The aqueous phase obtained by mixing C10-30 alkyl acrylate cross-linked polymer with water is used as phase C;

[0069] Mix salicylic acid and polyethylene glycol to obtain phase D;

[0070] Mix potassium hydroxide and water to obtain a potassium hydroxide solution as phase E;

[0071] The fragrance composition of PEG-7M, dimethicone, ethylhexylglycerin, phenoxyethanol, perfume, sodium chloride and rose essential oil is used as phase F;

[0072] Dispersing phase A in cold water and performing swelling treatment to obtain swollen phase A;

[0073] After mixing the swollen phase A with phase B, mix with phase C and phase D, then add phase E, and finally add phase F to obtain shampoo.

[0074] As an optional embodiment, the present invention can perform a swelling treatment after the cationic polymer in phase A is uniformly dispersed in cold water. In the present invention, the swelling treatment can be to raise the temperature to 80°C and then maintain the temperature at 80°C for 1 to 2 hours to obtain a completely swollen phase A, referred to as swollen phase A. After obtaining the swollen phase A, the present invention preferably mixes phase B with phase A to obtain phase AB. Preferably, when the phase B is mixed with phase A, the components of phase B can be mixed with phase A in sequence, or the components of phase B can be mixed and then mixed with phase A. After obtaining phase AB, the present invention preferably lowers the temperature of phase AB to 60°C, adds phase C and phase D in sequence, stirs evenly, and then adds phase E. Preferably, when adding phase C, the aqueous phase of the C10-30 alkyl acrylate crosslinked polymer of phase C can be directly added; when adding phase D, the components of phase D can be mixed before adding, or the components of phase D can be added in sequence. After adding phase E, the present invention preferably adjusts the pH value of the mixed system to 6.0, and finally cools to 45°C, and adds phase F to obtain shampoo. Preferably, the components of phase F can be added sequentially, or the components of phase F can be mixed and then added. The present invention does not specifically limit the order of adding the components of phase F sequentially.

[0075] In order to further illustrate the present invention, the technical solution provided by the present invention is described in detail below in conjunction with the accompanying drawings and embodiments, but they should not be construed as limiting the protection scope of the present invention.

[0076] The rose essential oil, rosemary essential oil and meadowfoam seed oil used in the following examples are commercially available products.

[0077] Example 1

[0078] A rose essential oil aromatic composition, comprising, by weight:

[0079] 2 parts rose essential oil, 2 parts rosemary essential oil and 20 parts meadowfoam seed oil.

[0080] The preparation method of the rose essential oil aromatic composition comprises the following steps: uniformly mixing rose essential oil, rosemary essential oil and meadowfoam seed oil according to weight parts.

[0081] Example 2

[0082] A rose essential oil aromatic composition, comprising, by weight:

[0083] 3 parts of rose essential oil, 1 part of rosemary essential oil and 20 parts of meadowfoam seed oil.

[0084] The preparation method of the rose essential oil aromatic composition comprises the following steps: uniformly mixing rose essential oil, rosemary essential oil and meadowfoam seed oil according to parts by mass.

[0085] Example 3

[0086] A rose essential oil aromatic composition, comprising, by weight:

[0087] 1 part rose essential oil, 3 parts rosemary essential oil and 20 parts meadowfoam seed oil.

[0088] The preparation method of the rose essential oil aromatic composition comprises the following steps: uniformly mixing rose essential oil, rosemary essential oil and meadowfoam seed oil according to weight parts.

[0089] Comparative Example 1

[0090] A rose essential oil aromatic composition, comprising, by weight:

[0091] 1 part rose essential oil and 5 parts meadowfoam seed oil.

[0092] The preparation method of the rose essential oil aromatic composition comprises the following steps: uniformly mixing the rose essential oil and meadowfoam seed oil according to parts by mass.

[0093] Comparative Example 2

[0094] A rose essential oil aromatic composition, comprising, by weight:

[0095] 1 part rosemary essential oil and 5 parts meadowfoam seed oil.

[0096] The preparation method of the rose essential oil aromatic composition comprises the following steps: uniformly mixing rosemary essential oil and meadowfoam seed oil according to weight parts.

[0097] Comparative Example 3

[0098] Use Limnanthes Alba seed oil as your essential oil.

[0099] Application Example 1

[0100] Malassezia inhibition experiment

[0101] 1. Experimental materials:

[0102] 1.1 Experimental strains:

[0103] Malassezia furfur is an anaerobic or facultative anaerobic bacterium. This strain was purchased from China National Center for Microbiological Culture Collection, with the collection number: ATCC14521.

[0104] 1.2 Experimental equipment:

[0105] Medicine spoon, centrifuge tube (50mL, 10mL), conical flask (250mL), pipette tip (200μL, 1000μL), EP tube, sterile gloves, sealing film, culture dish, coating rod, scalpel, long-handled tweezers, incubator, spectrophotometer, microscope, clean bench, centrifuge, autoclave. The above experimental equipment are all conventional laboratory equipment.

[0106] 1.3 Malassezia culture medium and culture conditions:

[0107] Culture medium: 2g / L beef extract, 1.5g / L peptone, 0.5g / L L-cystine, 15g / L agar (not added to liquid culture medium), sterilized at 121℃ for 15min. After sterilization, take out the culture bottles and test tubes and tighten the lids in time to reduce air entering the culture medium.

[0108] Malassezia culture: The bacteria are cultured on a plate medium until they grow into white and slightly yellow colonies with a smooth and moist appearance. Take a ring of the grown bacterial moss on the plate with an inoculation needle and inoculate it into the liquid culture medium. Seal the mouth of the test tube and shake it at 37°C on a shaker for 24 to 36 hours to obtain the Malassezia culture liquid.

[0109] Preparation of filter paper: Use a hole puncher to punch holes in three layers of folded filter paper, put the filter paper into a box and sterilize it at 121°C for later use.

[0110] Preparation of test solution:

[0111] The rose essential oil fragrance compositions of Examples 1 to 3 and Comparative Examples 1 to 2 and the essential oil of Comparative Example 3 were respectively solubilized with dimethyl sulfoxide (DMSO), and the amount of DMSO was 4 times the volume of the essential oil (the amount of DMSO in this embodiment was 4 times the volume of the essential oil, and in other cases, the amount of DMSO could also be 3 to 5 times the volume of the essential oil), and deionized water was used to prepare a test solution with a volume concentration of 5% of the essential oil and DMSO mixed solution. Among them, the test solution of the rose essential oil fragrance composition of Example 1 was used as sample No. 1; the test solution of the rose essential oil fragrance composition of Example 2 was used as sample No. 2; the test solution of the rose essential oil fragrance composition of Example 3 was used as sample No. 3; the test solution of the rose essential oil fragrance composition of Comparative Example 1 was used as sample No. 4; the test solution of the rose essential oil fragrance composition of Comparative Example 2 was used as sample No. 5; the test solution of the essential oil of Comparative Example 3 was used as sample No. 6; and at the same time, a 5% aqueous solution of dimethyl sulfoxide mass concentration without adding essential oil was used as a blank control group, recorded as sample No. 7. When performing the following inhibition zone determination, three parallel tests were performed for each sample.

[0112] 1.4 Determination method:

[0113] Malassezia inhibition test (filter paper inhibition zone method): inject a certain amount of Malassezia solution into the plate culture medium cooled to about 50°C, mix evenly, pour into the plate (about 20mL / plate), and let it stand horizontally until solidified. Then place the sterile filter paper evenly on the plate culture medium, 4 to 5 pieces per culture dish, use a pipette to draw 20μL of the test solution and drop it on the filter paper. Then place it in an anaerobic tank for culture, observe the changes in the inhibition zone for 24 to 36 hours, and record the diameter of the inhibition zone at 36 hours.

[0114] After 36 h of incubation, the diameter of the inhibition zone of each test group was observed and recorded as shown in Table 1 and Figure 1 shown.

[0115] Table 1 Diameter of inhibition zone in each test group

[0116] serial number Diameter of inhibition zone (mm) No. 1: Rose essential oil aroma composition (5%) 16.7 No. 2: Rose essential oil aroma composition (5%) 14.8 No. 3: Rose essential oil aroma composition (5%) 15.6 No. 4: Rose essential oil, meadowfoam seed oil (5%) 11.3 No. 5: Rosemary essential oil, Limnanthes bidentata seed oil (5%) 12.5 No. 6: Meadowfoam Seed Oil (5%) 6.6 No. 7: DMSO (5%, blank control) 6.3

[0117] The experimental results are shown in Table 1 and Figure 1 As shown, it can be seen that the inhibition zone of white pondweed seed oil relative to the blank control group did not change significantly, indicating that white pondweed seed oil basically does not have an inhibitory effect on Malassezia. The antibacterial effect of the rosemary essential oil and white pondweed seed oil composition can actually be regarded as the antibacterial effect of rosemary essential oil. The antibacterial effect of the rose essential oil and white pondweed seed oil composition can actually be regarded as the antibacterial effect of rose essential oil. The rose essential oil aromatic composition has a significant inhibitory effect on Malassezia at a concentration of 5%; the combination of two plant single essential oils and white pondweed seed oil also has a good inhibitory effect on Malassezia at a concentration of 5%; and the single white pondweed seed oil has basically no antibacterial effect, and only plays the role of base oil in the combination. It can be seen that the rose essential oil composition prepared by the present invention has a significant inhibitory effect on Malassezia, which is much better than a single single essential oil plus base oil, indicating that the synergistic effect is played between the various plant components after the prescription.

[0118] Application Example 2

[0119] Inhibition of LPS (lipopolysaccharide)-induced inflammation in zebrafish

[0120] The vertebrate zebrafish is a small tropical freshwater fish. Due to its small size, large spawning capacity suitable for high-throughput screening, transparent embryos, short experimental cycle and low cost, it has a wide range of application value in biomedical research, especially in the fields of molecular genetics, developmental biology and toxicology research. Its value as a model organism has been widely recognized.

[0121] LPS (lipopolysaccharide) treatment of zebrafish embryos can lead to a series of adverse reactions. As a common inflammatory stimulant, LPS can cause zebrafish embryos to have increased heart rate and morphological abnormalities such as yolk sac edema. It can also cause a significant increase in the levels of inflammatory factors in the young fish, such as tumor necrosis factor (TNF) and interleukin 6 (IL-6), thus showing a significant inflammatory response.

[0122] 1. Experimental Materials and Instruments

[0123] 1.1 Experimental Materials

[0124] The rose essential oil fragrance composition in Example 1 was dissolved with DMSO and subsequently prepared into a test solution of corresponding concentration; LPS (Sigma, USA, item number L2880); zebrafish interleukin 6 ELISA research kit (Jiangsu Enzyme Immunity Industrial Co., Ltd., item number MM-9111102); zebrafish tumor necrosis factor-α ELISA research kit (Jiangsu Enzyme Immunity Industrial Co., Ltd., item number MM-9111702)

[0125] Wild AB zebrafish were purchased from Nanjing Yishulihua Biotechnology Co., Ltd. The zebrafish embryos used in the experiment were cultured and incubated by the laboratory of the Nanjing Wild Plant Comprehensive Utilization Research Institute Testing Center. The culture and breeding conditions were referred to the "Zebrafish Book". Male and female fish were cultured separately, and the conductivity of the culture water was 450-550μs·cm -1 , the water temperature was 28°C, the light period was 14 hours and the darkness was 10 hours, and circulating water was used.

[0126] 1.2 Experimental instruments

[0127] Electronic balance (model FA2004HM, Shanghai Hengping Instrument Co., Ltd.), rotary evaporator (model RE00-Pro, Dalong Xingchuang Experimental Instrument Co., Ltd.), low-speed desktop centrifuge (model TDZ5-WS, Hunan Xiangyi Laboratory Instrument Development Co., Ltd.), microplate reader (model SpectraMax M2, Molecular Devices, USA), microscope (model MZ7, Guangzhou Mingmei Technology Co., Ltd.), ultrasonic machine (model JP 040S, Shenzhen Jiemeng Cleaning Equipment Co., Ltd.).

[0128] 1.3 Experimental methods

[0129] 1.3.1 Zebrafish feeding and embryo collection

[0130] Adult wild AB zebrafish were kept at room temperature (28°C) under a natural light cycle, with 14 hours of light and 10 hours of darkness per day. Zebrafish were fed brine shrimp twice a day. In the process of obtaining zebrafish embryos, healthy male and female fish were selected for natural mating in a 1:1 ratio. Spawning was allowed to occur naturally for two hours in an uninfluenced environment. Embryos were collected, impurities were cleaned in time, fish boxes were cleaned, and the embryo culture medium was replaced with embryo culture medium (3.5 g L -1 NaCl, 0.05 g L -1 KCl, 0.1 g L - 1 CaCl2, 0.025 g·L -1 NaHCO3) and transferred to a clean culture dish, that is, the fish embryos were changed from the ordinary zebrafish breeding water system to the special fish embryo culture medium system, and placed in an incubator for incubation at 28°C to prepare for subsequent experiments.

[0131] 15 μg mL -1 The LPS concentration of 100 μg / mL is the optimal concentration for inducing inflammation in zebrafish. It can significantly increase the ROS generation rate in zebrafish and cause significant changes in the yolk sac area, showing a comprehensive inflammatory response. At the same time, this concentration of LPS does not cause physiological damage to zebrafish, which meets the basic requirements for establishing an inflammatory model. When inducing the model, a certain amount of LPS is dissolved in the culture water (i.e., embryo culture medium) so that the final LPS concentration in the water reaches 15 μg / mL. -1 , zebrafish embryos were transferred into this culture water for model induction.

[0132] 1.3.2 Evaluation of anti-inflammatory activity of samples

[0133] In order to further explore the effects of different concentrations of rose essential oil compositions on the zebrafish inflammation model, a blank group, an LPS-induced model group, a dexamethasone positive control group, and a sample group were set up. The sample group was set up with three concentrations of high, medium, and low. The rose essential oil fragrance composition of Example 1 was added at a mass concentration of 0.15 mg mL -1 , 0.10mg·mL -1 , 0.05mg·mL -1 The test solutions are called high-dose sample group, medium-dose sample group and low-dose sample group. Each test group uses 30 fish embryos for the test.

[0134] The specific test settings are:

[0135] The blank group used embryo culture medium to culture zebrafish embryos;

[0136] In the LPS-induced model group, LPS was added to the embryo culture medium to make the concentration of LPS in the embryo culture medium 15 μg mL -1, zebrafish embryos were cultured using embryo culture medium containing LPS;

[0137] In the dexamethasone positive control group, LPS was added to the embryo culture medium to make the concentration of LPS in the embryo culture medium 15 μg mL -1 , while adding LPS, dexamethasone was also added to the embryo culture medium to a concentration of 2.415 μg·mL -1 , zebrafish embryos were cultured using embryo culture medium containing LPS and dexamethasone;

[0138] In the high-dose sample group, LPS was added to the embryo culture medium to make the concentration of LPS in the embryo culture medium reach 15 μg·mL -1 When LPS was added, the rose essential oil fragrance composition of Example 1 was also added to the embryo culture medium to a mass concentration of 0.15 mg·mL -1 , zebrafish embryos were cultured using corresponding embryo culture medium;

[0139] In the medium-dose sample group, LPS was added to the embryo culture medium to make the concentration of LPS in the embryo culture medium 15 μg mL -1 When LPS was added, the rose essential oil fragrance composition of Example 1 was also added to the embryo culture medium to a mass concentration of 0.10 mg·mL -1 , zebrafish embryos were cultured using corresponding embryo culture medium;

[0140] In the low-dose sample group, LPS was added to the embryo culture medium to make the concentration of LPS in the embryo culture medium 15 μg mL -1 When LPS was added, the rose essential oil fragrance composition of Example 1 was also added to the embryo culture medium to a mass concentration of 0.05 mg·mL -1 , zebrafish embryos were cultured using the corresponding embryo culture medium.

[0141] After 72 hours of zebrafish embryo culture, the survival rate, heart rate ratio (ie, heart rate of the experimental group / heart rate of the blank group) and changes in yolk sac area of ​​the zebrafish were observed.

[0142] The rose essential oil composition test solution of Example 1 was subjected to three test groups again, that is, the rose essential oil composition was added to the embryo culture medium to make the final concentration of the rose essential oil composition in the system 0.15 mg·mL -1 , 0.10mg·mL -1 , 0.05mg·mL -1 Then, LPS was added to the three experimental groups to make the final concentration of LPS in the system 15 μg·mL -1Thirty fish embryos were placed in each test group. After incubation for 72 hours, zebrafish embryos were collected and added with PBS buffer at a ratio of 1:9. The tissues were minced and centrifuged at high speed at 4°C. The supernatant solution was taken and operated according to the instructions of the ELISA kit to detect the effects of each concentration of the test solution on TNF-α and IL-6 inflammatory factors.

[0143] 1.3.3 Experimental results

[0144] The survival rate and heart rate ratio of zebrafish in different experimental groups are shown in Table 2; Figure 2 As shown; the heart rate of zebrafish in different experimental groups is as follows Figure 3 The effects of different experimental groups on zebrafish yolk sac area and fluorescence intensity are shown in Figure 4 The levels of inflammatory factors in zebrafish in different experimental groups are shown in Table 3; The effects of different experimental groups on the levels of IL-6 inflammatory factors in zebrafish are shown in Figure 5 The effects of different experimental groups on the level of TNF-α inflammatory factor in zebrafish are shown in Figure 6 shown.

[0145] Table 2 Survival rate and heart rate ratio of zebrafish in different experimental groups

[0146] Group Survival rate (%) Heart rate (30s) Heart rate ratio Blank Group 83.2 74 1 Model Group 71.9 102 1.38 Positive control group 84.6 90 1.22 Sample 0.15mg / mL 82.1 94 1.27 Sample 0.10mg / mL 83.3 96 1.3 Sample 0.05mg / mL 83.7 99 1.34

[0147] Table 2 Figure 2 and Figure 3 The results show that 0.15 mg·mL -1 The rose essential oil fragrance composition had a higher survival rate and was basically equivalent to the blank control group, 0.15 mg·mL -1 The heart rate ratio of the rose essential oil aroma composition to the blank group was significantly lower than that of the model group and slightly higher than that of the positive control group. -1 The rose essential oil aroma composition is beneficial to relieve the increased heart rate caused by LPS. 0.15mg·mL -1 The rose essential oil aroma composition treatment group was relative to 0.05 mg·mL -1 and 0.10 mg mL -1 The rose essential oil aromatherapy combination treatment group had a more significant effect in reducing heart rate, so 0.15 mg·mL was selected in the subsequent treatment. -1 The yolk sac area image under the microscope and the fluorescence intensity analysis were performed in the rose essential oil fragrance composition treatment group. Figure 4 The results showed that 0.15 mg·mL -1 The rose essential oil aromatherapy composition treatment group can inhibit the increase of yolk sac area and ROS rate caused by LPS-induced inflammation. The levels of inflammatory factors in the body were further determined.

[0148] Table 3 Levels of inflammatory factors in zebrafish in different experimental groups

[0149] Group IL-6 level (pg / mL) TNF-α level (pg / mL) Blank Group 9.7 19.7 Model Group 12.4 31.4 Positive control group 10.8 24.9 Sample 0.15mg / mL 11.4 27.8

[0150] Solid samples were prepared according to the instructions of the ELISA kit to determine the inflammatory factors, as shown in Table 3, Figure 5 and Figure 6 As shown. 0.15mg·mL -1 The release levels of TNF-α and IL-6 in zebrafish treated with the rose essential oil aromatic composition were significantly lower than those in the model group and slightly higher than those in the positive control group, indicating that the rose essential oil composition can inhibit the production of inflammatory factors TNF-α and IL-6 and inhibit the development of inflammation.

[0151] As a common inflammatory stimulant, LPS can cause morphological abnormalities such as increased heart rate and yolk sac edema in zebrafish embryos. It may also lead to a significant increase in the levels of inflammatory factors such as tumor necrosis factor (TNF-α) and interleukin 6 (IL-6) in the young fish, thus showing an obvious inflammatory response.

[0152] Different concentrations of rose essential oil aromatherapy compositions showed different effects in treating inflamed zebrafish. The active ingredients in the rose essential oil aromatherapy compositions can slow down the heart rate of young fish and gradually restore it to a normal heart rate level, effectively alleviating the toxic reaction caused by LPS stimulation. At the same time, they can also reduce the yolk sac area of ​​inflamed zebrafish and further improve the morphological abnormalities of the embryos. 0.15mg·mL -1 The rose essential oil composition also has a good inhibitory effect on LPS-induced inflammation.

[0153] Application Example 3

[0154] Experiment on the effect of rose essential oil aromatherapy combination on sleep-inducing effect in mice

[0155] 1. Experimental Materials and Methods

[0156] Experimental Materials

[0157] Experimental reagents

[0158] In the rose essential oil fragrance composition in Example 1, p-chlorophenylalanine (PCPA, batch number C6907) and sodium pentobarbital (batch number P4213) are products of Sigma Company, USA; chloral hydrate and formaldehyde are from Chengdu Kelong Chemical Reagent Factory; physiological saline; and purified water.

[0159] Experimental animals

[0160] 72 healthy clean grade male SD rats, 10-12 weeks old, weighing 180-220 g, were provided by the Experimental Animal Research Center of Nanjing University of Chinese Medicine.

[0161] Experimental methods

[0162] Preparation of rat insomnia model

[0163] The rats were weighed after 2 weeks of adaptive feeding. Except for the blank control group, the other rats were intraperitoneally injected with PCPA (chlorophenylalanine) suspension (400 mg / kg, dissolved in weak alkaline saline) for 2 consecutive days. The blank group rats were intraperitoneally injected with an equal volume of weak alkaline saline. 28 to 36 hours after the first intraperitoneal injection, the rats showed circadian rhythm loss and were active both during the day and at night. The sodium pentobarbital righting test was used to record the sleep latency and sleep duration of the blank group and the modeling group.

[0164] Experimental groups and methods

[0165] 72 healthy SD rats were randomly divided into 6 groups, 12 in each group, including a blank group (30 mL of purified water), a model group (30 mL of purified water), and an essential oil group (aromatherapy liquid was prepared by adding 0.5 mL of the rose essential oil fragrance composition in Example 1 to 30 mL of purified water). Each aromatherapy was performed for 30 min, 3 times a day, for 5 consecutive days.

[0166] Experiment on sleep latency and sleep duration induced by sodium pentobarbital in rats

[0167] After the PCPA model was successfully established, the essential oil group was fumigated with aromatherapy for 30 minutes every day, 3 times a day, for 5 consecutive days; the blank group and the model group were fumigated with pure water instead of aromatherapy liquid. 60 minutes after the last aromatherapy, the rats were intraperitoneally injected with 36 mg / kg of sodium pentobarbital. The sleep latency and sleep duration of the rats were observed. The disappearance of righting reflex was used to determine the occurrence of sleep. The sleep latency and sleep duration of each rat were recorded.

[0168] 2. Experimental results

[0169] The test results of the sodium pentobarbital sleep model in each experimental group are shown in Table 4.

[0170] Table 4 Test results of each experimental group on sodium pentobarbital sleep model

[0171]

[0172]

[0173] Note: Compared with the blank group, aP<0.05; compared with the model group, bP<0.05.

[0174] As shown in Table 4, there was a significant difference between the blank group and the modeling group (P<0.05), and the modeling was successful. In terms of sleep latency, compared with the blank control group, the essential oil group could significantly shorten the sleep latency of rats; in terms of sleep duration, compared with the blank control group, the essential oil group could significantly prolong the sleep duration of rats.

[0175] Sleep disorder refers to the abnormality of the quantity or quality of sleep. Long-term insomnia will have a serious impact on physical and mental health. There are many drugs for treating insomnia, but most of them will cause dependence. The aromatic essential oils derived from natural plants have a rich and soft fragrance, no irritation, and no toxic side effects. It can be seen from the experimental results that the rose essential oil aromatic composition prepared by the present invention has the effects of soothing emotions and helping sleep.

[0176] Example 4

[0177] A shampoo, the composition of which is shown in Table 5.

[0178] Table 5 Composition of shampoo

[0179]

[0180]

[0181] The preparation method of shampoo is:

[0182] Disperse phase A evenly with cold water, then heat it to 80℃ and keep it for 1-2h. After swelling is complete, add the completely mixed phase B components and stir evenly. After cooling to 60℃, add the pre-mixed phase C and phase D, stir evenly, add phase E and adjust the pH of the system to 6.0. After cooling to 45℃, add the phase F components in sequence and stir evenly to prepare shampoo.

[0183] Comparative Example 4

[0184] A shampoo, the composition and preparation method are the same as those of Example 4, the only difference being that no rose essential oil fragrance composition is added.

[0185] Application Example 4

[0186] Evaluation of the shampoos of Example 4 and Comparative Example 4

[0187] 60 volunteers aged 18 to 60 were selected, half of them were male and half were female, and divided into two groups, 30 people in each group, half of them were male and half were female. One group used the shampoo of Example 4, and the other group used the shampoo of Comparative Example 4. The shampoo was used once every 2 days before going to bed, and a questionnaire evaluation was conducted after continuous use for 3 weeks. The results are shown in Table 6.

[0188] Table 6 Consumer evaluation form after using shampoo (30 people in each group)

[0189]

[0190]

[0191] It can be seen from the statistical results in Table 6 that the shampoo with the rose essential oil fragrance composition added has obvious advantages over the shampoo without the rose essential oil fragrance composition in terms of fragrance, comfort, pleasant mood, sleep-aiding effect, and healthy feeling of scalp and hair. During the trial of the shampoo with the rose essential oil fragrance composition added, the consumers expressed their approval of the fragrance, comfort, mood-relieving and sleep-aiding effect of the shampoo, and the improvement of the health of the scalp and hair.

[0192] In summary, the rose essential oil aromatic composition provided by the present invention has a simple ratio and a fragrant smell; after the three kinds of plant essential oils are compounded, they exert a synergistic effect, have an excellent inhibitory effect on Malassezia; have an excellent anti-inflammatory effect on the zebrafish inflammation model caused by LPS; and have an obvious sleep-promoting effect on the insomnia model of pentobarbital sodium rats. And the composition can be applied to the formula of hair and skin daily chemical products, can effectively play an antibacterial and anti-inflammatory role, thereby regulating the balance of skin microecology; at the same time, its fragrant smell can also play a role in soothing emotions and helping sleep.

[0193] Although the above embodiment describes the present invention in detail, it is only a part of the embodiments of the present invention, not all of the embodiments. People can also obtain other embodiments based on this embodiment without creativity, and these embodiments all fall within the protection scope of the present invention.

Claims

1. A rose essential oil aromatic composition, characterized in that: include: Rose essential oil, rosemary essential oil and meadowfoam seed oil.

2. The rose essential oil aromatic composition according to claim 1, characterized in that: In parts by mass, the mass ratio of rose essential oil, rosemary essential oil and meadowfoam seed oil in the rose essential oil fragrance composition is (1-6):(1-3):(10-30).

3. The rose essential oil fragrance composition according to claim 1 or 2, characterized in that: The rose essential oil includes one or more of rose flower oil, rose flower oil, Damask rose flower oil, French rose flower oil and centifolia rose flower oil; the rosemary essential oil includes rosemary leaf oil.

4. The method for preparing the rose essential oil fragrance composition according to any one of claims 1 to 3, characterized in that: The following steps are involved: Rose essential oil, rosemary essential oil and meadowfoam seed oil are mixed according to parts by mass.

5. Use of the rose essential oil fragrance composition according to any one of claims 1 to 3 or the rose essential oil fragrance composition prepared by the preparation method according to claim 4 in the preparation of anti-inflammatory and soothing daily chemical products.

6. Use of the rose essential oil fragrance composition according to any one of claims 1 to 3 or the rose essential oil fragrance composition prepared by the preparation method according to claim 4 in the preparation of antibacterial daily chemical products.

7. Use of the rose essential oil fragrance composition according to any one of claims 1 to 3 or the rose essential oil fragrance composition prepared by the preparation method according to claim 4 in the preparation of sleep-aiding daily chemical products.

8. A shampoo, characterized in that: The invention comprises the rose essential oil aromatic composition according to any one of claims 1 to 3 or the rose essential oil aromatic composition prepared by the preparation method according to claim 4.

9. The shampoo according to claim 8, characterized in that The shampoo further comprises the following components in percentage by mass: 8-20% of surfactant, 0-5% of hair conditioner, 0-1% of antidandruff agent, 0-1% of preservative, 0-2% of sodium chloride, 0-2% of pH regulator, 0-2% of rheology modifier, 0-2% of fragrance and water.

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