Pathological section scanner
By introducing detection components and automated transfer mechanisms into the pathological section scanner, the problem of insufficient slice status monitoring is solved, and efficient and safe slice transfer is achieved without guarding, improving work efficiency and equipment stability.
Patent Information
- Application Number
- CN202411318543.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-20
- Publication Date
- 2025-01-10
AI Technical Summary
The existing pathological section scanner lacks detection mechanism during section transfer, resulting in the failure to monitor the section status in real time, which may lead to abnormal transfer, affecting work efficiency and section safety.
A pathological slice scanner including a loading and unloading mechanism and a scanning mechanism is designed. The loading and unloading mechanism includes a detection component for detecting slice status information, and the rapid and accurate transfer of slices is achieved through the material transfer assembly and the conveying assembly to avoid manual participation and improve the Work efficiency.
It realizes rapid transfer of unattended slices, reduces labor costs, avoids slice damage and transfer abnormalities, and improves the working efficiency and safety of pathological slice scanners.
Smart Images

Figure CN119290750A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of medical devices, and in particular to a pathology slice scanner. Background Art
[0002] Pathology slice scanners can obtain high-speed, accurate, non-defocused, reproducible and storable digital slice information, which has attracted great attention from the medical, scientific research and teaching circles. They are used to examine the pathological morphology of pathological changes in organs, tissues or cells of the body.
[0003] However, the existing pathology slice scanner does not detect the slices in the conveying component during the slice transfer process, and thus cannot obtain the slice status information. It is easy for the abnormal state of the slice to cause the material transfer component to be unable to quickly transfer the slices in the conveying component, and even cause the slices to break during the transfer process, thereby affecting the working efficiency of the pathology slice scanner. Summary of the invention
[0004] The present application provides a pathology slice scanner, which can realize rapid transfer of slices through the cooperation of a detection component with a material transfer component, does not require special personnel on duty, and improves the working efficiency of the pathology slice scanner.
[0005] The present application provides a pathology slice scanner, including a loading and unloading mechanism, a scanning mechanism and a frame.
[0006] The scanning mechanism comprises a stage for placing the slices and a scanning component for scanning the slices;
[0007] The loading and unloading mechanism includes a material moving component, a conveying component and a loading component. The stage, the scanning component, the material moving component, the conveying component and the loading component are all arranged on the frame. The material moving component is used to move the slices on the loading component to the stage and / or move the slices scanned on the stage to the loading component. The conveying component is used to transport the slices on the loading component.
[0008] Wherein, the loading and unloading mechanism further includes a detection component for detecting status information of the slices placed in the loading component, so that the material moving component can move the slices in the loading component according to the status information detected by the detection component.
[0009] In a scanner according to one embodiment of the present application, the detection component includes a detection module and a detection bracket, the detection module is installed on the frame through the detection bracket, and the conveying component is located below the detection module.
[0010] In a scanner according to one embodiment of the present application, the conveying assembly has a slice feeding station and a slice removing station, the detection module is arranged above the slice feeding station, and the position of the slice removing station corresponds to the position of the stage.
[0011] In a scanner of one embodiment of the present application, the position of the material moving assembly corresponds to the position of the slice moving out station, so that the material moving claw of the material moving assembly can move vertically to the loading assembly to take out the slice in the loading assembly.
[0012] In a scanner of one embodiment of the present application, the material moving assembly includes a material moving clamp and a moving assembly, and the material moving clamp is installed on the frame through the moving assembly, so that the moving assembly can drive the material moving clamp to move along at least one degree of freedom direction, so as to realize the transfer of the slice between the stage and the loading assembly.
[0013] In a scanner of one embodiment of the present application, the conveying assembly has a slice feeding station and a slice removing station, the detection assembly is arranged at the slice feeding station, and the moving assembly includes a vertical assembly, and the vertical assembly is used to drive the material moving clamp to move up and down in the vertical direction.
[0014] When the material moving clamp is moved downward by the vertical component, the material moving clamp takes out the slice to be scanned from the loading and unloading component from above.
[0015] In a scanner of one embodiment of the present application, the moving component includes a longitudinal component, and the longitudinal component is used to drive the material moving clamp to move forward and backward in the horizontal direction. When the material moving clamp is moved to the rear by the longitudinal component, the slice to be scanned is placed on the stage.
[0016] In a scanner of one embodiment of the present application, the material transfer clamp includes a clamp structure and a rotating structure, and the clamp structure is connected to the moving component through the rotating structure, so that the clamp structure can rotate around the rotating axis of the rotating structure toward one side of the stage.
[0017] In a scanner of one embodiment of the present application, the material transfer clamp includes a first clamp and a second clamp, and the first clamp and the second clamp are arranged at intervals along the conveying direction of the conveying component to alternately realize the slice transfer between the stage and the loading component.
[0018] In a scanner of one embodiment of the present application, the moving component also includes a transverse component, which is used to drive the first jaw and the second jaw to move left and right in a horizontal direction. When the first jaw takes the scanned slice out of the stage, the transverse component drives the second jaw to place the slice to be scanned onto the stage.
[0019] In a scanner of one embodiment of the present application, the loading assembly includes a loading seat for placing a slice rack and a positioning assembly for limiting the position of the slice rack, the loading seat is connected to the conveying assembly, and the positioning assembly is arranged on the loading seat for limiting the slice rack in the accommodating groove.
[0020] In a scanner according to one embodiment of the present application, the conveying assembly includes a conveying track, the loading assembly reciprocates along the length direction of the conveying track, and the length direction of the loading seat is perpendicular to the length direction of the conveying track.
[0021] In a scanner of one embodiment of the present application, the loading seat includes a base, which is tilted toward a side away from the stage, so that the slices of the slice rack placed on the loading seat can be tilted toward a side away from the stage.
[0022] In the scanner of one embodiment of the present application, the inclination angle of the base is between 1 degree and 10 degrees; and / or waist grooves are provided on both sides of the loading seat.
[0023] The technical solution provided by the embodiments of the present application may include the following beneficial effects: The present application designs a pathology slice scanner, including a loading and unloading mechanism and a scanning mechanism. The loading and unloading mechanism includes a material moving component, a conveying component, a loading component and a detection component. The scanning mechanism includes a stage for placing slices and an image recognition component for reading information on the slices. The conveying component is used to convey the slices on the loading component. The material moving component is used to transfer the slices on the loading component to the stage and / or transfer the slices scanned on the stage to the loading component. The detection component is used to detect the status information of the slices placed in the loading component, so that the material moving component can transfer the slices in the loading component according to the status information detected by the detection component, thereby realizing fast and accurate replacement of slices without the need for special personnel on duty, thereby improving the working efficiency of the pathology slice scanner.
[0024] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.
[0026] Figure 1 It is a partial schematic diagram of a pathology slice scanner provided by an embodiment of the present application;
[0027] Figure 2 yes Figure 1 A schematic diagram of the structure of the scanning mechanism in FIG.
[0028] Figure 3 yes Figure 1 Structural schematic diagram of the loading and unloading mechanism in FIG.
[0029] Figure 4 yes Figure 3 An exploded schematic diagram of the loading and unloading mechanism in FIG.
[0030] Figure 5 yes Figure 4 A schematic diagram of the structure of the material transfer assembly in FIG.
[0031] Figure 6 yes Figure 5 An exploded schematic diagram of the material transfer assembly in FIG.
[0032] Figure 7 yes Figure 3 A schematic diagram of a conveying component and a loading component in FIG.
[0033] Figure 8 yes Figure 7 Schematic diagram of the exploded view of the loading assembly and slice holder in.
[0034] Description of reference numerals:
[0035] 100. Material transfer assembly;
[0036] 10. Material transfer clamp; 10a. First clamp; 10b. Second clamp; 10c. Rotating structure; 101c. First connecting part; 102c. First connecting block; 10d. Connecting assembly; 11. Clamping part; 11a. First clamp; 11b. Second clamp; 10e. First fixed block; 10f. First mounting block; 10g. First movable block; 10f. First detecting part; 10g. Second detecting part; 111. Clamp; 12. Clamp driving member;
[0037] 20. longitudinal assembly; 21. longitudinal mounting plate; 211. first longitudinal mounting plate; 212. second longitudinal mounting plate; 22. longitudinal driving member; 23. longitudinal transmission member; 231. longitudinal gear; 232. longitudinal rack; 24. longitudinal guide member;
[0038] 30. Transverse assembly; 31. Transverse mounting plate; 311. First transverse mounting plate; 312. First transverse mounting frame; 32. Transverse driving member; 33. Transverse transmission member; 331. Transverse gear; 332. Transverse rack; 34. Transverse guide member;
[0039] 40, vertical assembly; 41, vertical connecting seat; 411, vertical seat body; 412, vertical cover plate; 42, vertical driving member; 43, vertical transmission member; 44, vertical mounting seat; 45, vertical supporting seat;
[0040] 200, loading assembly; 200a, receiving groove; 201, loading seat; 202, positioning structure;
[0041] 300, conveying assembly; 300a, slice feeding station; 300b, slice removal station; 301, conveying seat; 302, conveying track; 303, conveying motor; 304, limiting structure;
[0042] 400, scanning mechanism; 401, stage; 402, image recognition component; 403, moving part; 404, scanning base; 405, scanning component;
[0043] 500, detection component; 501, detection module; 5011, camera; 502, detection bracket;
[0044] 600, slice rack;
[0045] 700. Slice. DETAILED DESCRIPTION
[0046] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.
[0047] It should also be understood that the terms used in this specification of the present application are only for describing specific realities. In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate the orientation or position relationship based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. In addition, the terms "first" and "second" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present application, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.
[0048] In conjunction with the accompanying drawings, some embodiments of the present application are described in detail below. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other.
[0049] like Figure 1 to Figure 2 As shown, the present application provides a pathology slice scanner, including a loading and unloading mechanism, a scanning mechanism 400 and a frame, wherein the loading and unloading mechanism and the scanning mechanism 400 are both installed in the frame, and the loading and unloading mechanism is used to transport the slice 700 to the scanning mechanism 400 for scanning, and then move the slice 700 scanned by the scanning mechanism 400 out, and the whole process does not require manual participation, and the slice 700 can be moved quickly and accurately, reducing the manual participation process of the slice 700 during the transfer process, which not only reduces the labor cost, but also improves the working efficiency of the pathology slice scanner, and greatly avoids the problem of fragmentation or slice damage due to manual participation.
[0050] In an optional embodiment, if Figure 1 to Figure 2 As shown, the scanning mechanism 400 includes a stage 401 and a scanning component 405. The stage 401 is set on the frame for placing the slice 700; the scanning component 405 is set above the stage 401 for scanning the pathological tissue to be analyzed on the slice to obtain the pathological information on the slice.
[0051] In an optional embodiment, the scanning component 405 includes a plurality of microscope objective lenses, and the plurality of microscope objective lenses are arranged in an array to form an array objective lens, and the array objective lens can cover at least the width of the tissue on the slice 700 to be scanned in the effective scanning width area in the length direction of the slice 700. That is, when the pathological slice scanner performs pathological analysis, the pathological tissue to be analyzed on the slice 700 and the cover glass are offset, and the scanning width of the array objective lens is greater than or equal to the sum of the width of the pathological tissue and the position offset of the pathological tissue on the slice 700. In this way, the unidirectional movement of the slice 700 can be achieved, so that when passing through the scanning component 405, the scanning area of the array objective lens can cover all the slice parts to be scanned directly below the scanning component 405, ensuring that the omnidirectional scanning of the slice 700 can be achieved without moving the scanning component 405.
[0052] In an optional embodiment, the scanning mechanism 400 further includes an image recognition component 402, and the image recognition component 402 is used to read the identity information on the slice 700 to organically combine the identity information on the slice 700 with the pathological information.
[0053] The slice 700 has a scanning area and a marking area. The scanning area has a pathological tissue to be analyzed and a cover glass. The marking area is provided with identity information recording relevant information of the slice 700. The identity information includes but is not limited to a QR code, a barcode or a handwritten mark. In this embodiment, the image recognition component 402 is used to read the identity information on the slice 700 to obtain the identity information on the slice 700; the scanning component 405 is used to scan the pathological tissue to be analyzed to obtain the pathological information on the slice. Therefore, the present application can organically combine the identity information and the pathological information on the slice 700 through the setting of the image recognition component 402.
[0054] In an optional embodiment, the scanning mechanism 400 includes a moving part 403 and a scanning base 404, the stage 401 is mounted on the scanning base 404 via the moving part 403, and the image recognition component 402 is disposed above the stage 401 and located on a side close to the loading and unloading mechanism, so that the information on the slice 700 can be read after the slice 700 is placed on the stage 401. The moving part 403 is used to drive the stage 401 to drive the slice 700 to move to the detection position along the guide direction of the moving part 403, so that the scanning component 405 at the detection position can scan the slice 700 to obtain the pathological information on the slice, so that the identity information on the slice can be organically combined with the pathological information.
[0055] In an optional embodiment, if Figures 1 to 4As shown, the loading and unloading mechanism includes a material moving component 100, a conveying component 300 and a loading component 200, and the material moving component 100, the conveying component 300 and the loading component 200 are all arranged on the frame. Among them, the conveying component 300 is used to transport the slices 700 on the loading component 200, and the material moving component 100 is used to transfer the slices 700 on the loading component 200 to the stage 401, and / or transfer the slices 700 scanned on the stage 401 to the loading component 200. The whole process does not require manual participation, which greatly avoids the problem of fragments or slice damage caused by manual participation. The structure is simple and the operation is convenient, which not only reduces the labor cost, but also improves the working efficiency of the pathology slice scanner.
[0056] It should be noted that a receiving groove 200a is formed in the loading component 200, and the receiving groove 200a can be used to place the slice 700. The receiving groove 200a can be used to place the slice rack 600 containing the slice 700, so that the slice 700 or the slice rack 600 can be moved to the position of the stage 401 through the conveying component 300, and then moved to the stage 401 through the material moving component 100. The stage 401 moves along the conveying direction perpendicular to the conveying component 300 under the drive of the moving component 403, and the identity information on the slice is organically combined with the pathological information. After the scanning of all the slices 700 is completed, the material moving component 100 transfers the slice 700 from the stage 401 to the loading component 200, and the conveying component 300 then moves the loading component 200 with the slice 700 or the slice rack 600 placed thereon to the outside of the rack, so as to retrieve the slice 700 or the slice rack 600.
[0057] In an optional embodiment, the loading and unloading mechanism further includes a detection component 500, which is used to detect the status information of the slice 700 placed in the loading component 200, so that the material moving component 100 can move the slice 700 in the loading component 200 according to the status information detected by the detection component 500. The detection component 500 is installed on the frame, and the status information of the slice 700 may include the status information of the slice 700 placed in the receiving groove 200a, and the status information of the slice 700 may also include the status information of the slice 700 placed in the slice rack 600, which is not limited in the present application. Exemplarily, the detection component 500 can be used to detect the deflection value of the slice 700 in the receiving groove 200a or the slice rack 600, and then compare the measured deflection value with the pre-stored standard deflection value to determine whether the slice 700 in the receiving groove 200a or the slice rack 600 is in a state of slanting, overlapping or missing; or, the detection component 500 can be used to detect the distance value between two adjacent slices 700, and then compare the measured distance value with the pre-stored standard distance value to determine whether the slice 700 in the receiving groove 200a or the slice rack 600 is in a state of slanting, overlapping or missing; or, the detection component 500 can be used to detect the number of slices 700 in the receiving groove 200a or the slice rack 600, and then compare the measured number with the pre-stored standard number to determine whether the slice 700 in the receiving groove 200a or the slice rack 600 is in a state of overlapping, slanting or missing, and so on.
[0058] Therefore, the material moving component 100 can transfer the slice 700 in the receiving groove 200a or the slice rack 600 to the stage 401 for scanning according to the detected status information, and then transfer the scanned slice 700 from the stage 401 to the corresponding position of the receiving groove 200a or the slice rack 600, without the need for manual correction by the operator, which not only saves time and improves work efficiency; but also avoids accidents during the transfer of the slice 700 by the material moving component 100, such as the risk of the slice 700 being broken during clamping, the problem of the slice 700 falling during transfer, or the slice 700 being tilted and skewed during the transfer process, or the abnormal state of the slice 700 in the receiving groove 200a or the slice rack 600 causing the material moving component 100 to be unable to transfer, etc., thereby fully improving the safety of unattended operation, ensuring that the slice 700 can be accurately transferred to the stage 401 for scanning, and ensuring work efficiency.
[0059] In an optional embodiment, the detection component 500 includes a detection module 501 and a detection bracket 502. The detection module 501 is installed on the frame through the detection bracket 502, and the conveying component 300 is located below the detection module 501, so that the detection module 501 can detect the slice 700 placed in the loading component 200 to obtain the status information of the slice 700, so that the material moving component 100 can transfer the slice 700 in the receiving groove 200a or the slice rack 600 to the stage 401 for scanning according to the detected status information. There is no need for an operator to monitor the entire process, which saves time and improves the transfer efficiency of the material moving component 100, and also avoids the occurrence of abnormalities such as slice dropping and fragmentation during the transfer of the slice 700 by the material moving component 100.
[0060] It should be noted that the detection bracket 502 may be a separate structural member, or may be a partial structure of a rack, and its main purpose is to achieve fixed installation of the detection module 501, which is not limited in the present application.
[0061] Exemplarily, when the detection module 501 detects that the slices 700 in the receiving groove 200a or the slice rack 600 have state information of oblique insertion, overlapping or missing slices, the material moving component 100 may not need to move the slices 700 with abnormal state information, eliminating the tediousness of on-site monitoring by the operator, and reducing the waiting time for re-placing the slices 700 with abnormal state information, thereby ensuring the working efficiency of the pathological slice scanner, and avoiding the risk of fragments when the material moving component 100 clamps these abnormal slices 700, thereby greatly protecting the safety of the slices 700. In addition, the detection module 501 can also output the state information detected by the detection module 501 through the output module of the pathological slice scanner, so that the operator can conduct a re-inspection after the slice 700 is scanned, or remove the slices 700 with abnormal state information such as oblique insertion, overlapping or missing slices.
[0062] It should be noted that since the slice 700 is made of glass, which is fragile, slippery and thin, the material transfer assembly 100 is relatively troublesome in transferring the slice 700. The slice 700 needs to be placed neatly in the receiving groove 200a or the slice rack 600. The placement of the slice 700 may easily cause the slice 700 to be pinched and broken, and may also easily affect the flatness of the slice 700 placed on the stage 401. Therefore, the present application detects the number of slices 700 to be scanned in the receiving groove 200a or the slice rack 600 through the detection module 501, and confirms whether there are overlapping, obliquely inserted and missing slices, so that the material moving component 100 can transfer the slices 700 in the receiving groove 200a or the slice rack 600 to the stage 401 for scanning according to the detected status information, and then transfer the scanned slices 700 from the stage 401 to the corresponding position of the receiving groove 200a or the slice rack 600, so as to achieve precise positioning of the slices 700 without the need for manual correction by the operator, thereby saving time and improving work efficiency.
[0063] In an optional embodiment, the conveying component 300 has a slice feeding station 300a and a slice removing station 300b, and the detection module 500 is arranged above the slice feeding station 300a, and the position of the slice removing station 300b corresponds to the position of the stage 401, so that the detection module 500 can detect the status information of the slice 700 in the receiving groove 200a or the slice rack 600 at the slice feeding station 300a, and then transmit the detected status information to the controller of the pathology slice scanner, so that the controller can control the material moving component 100 to work according to the detected status information, and transfer the slice 700 in the receiving groove 200a or the slice rack 600 to the stage 401 for scanning. Among them, since the position of the slice removal station 300b corresponds to the position of the stage 401, the material transfer component 100 can quickly transfer the slice 700 in the accommodating groove 200a or the slice rack 600 to the stage 401 for scanning without the need for unnecessary actions. The slice 700 can be efficiently transferred, and the structure of the entire pathology slice scanner can be simplified to reduce its size.
[0064] Exemplarily, the detection component 500 includes a camera 5011, which is arranged above the slice feeding station 300a or on the side of the conveying component 300 close to the slice feeding station 300a, so that the camera 5011 can perform a one-time identification of the slice 700 in the receiving groove 200a or the slice rack 600 at the slice feeding station 300a, without the need to perform separate detection on each slice; then the camera 5011 transmits the detected status information to the controller of the pathology slice scanner, so that the controller can transfer the slice 700 in the receiving groove 200a or the slice rack 600 to the stage 401 for scanning when the loading component 200 is transported to the slice removal station 300b, which is beneficial to improving the working efficiency of the pathology slice scanner.
[0065] In an optional embodiment, the state information includes at least one of the tilt state, arrangement state and abnormal state of the slice 700. The tilt state refers to whether the slice 700 is tilted or inserted obliquely in the receiving groove 200a or the slice rack 600, the arrangement state refers to whether the slice 700 is overlapped or missing in the receiving groove 200a or the slice rack 600, and the abnormal state refers to other states of the slice 700 in the receiving groove 200a or the slice rack 600 except the tilt state and arrangement state, including but not limited to the state of the slice 700 being broken.
[0066] It should be noted that the slices 700 of the present application are stored in a special slice rack 600, and the slice rack 600 can be stored in the storage mechanism of the pathology slice scanner. When the scanning mechanism 400 needs to read the information of the slice 700, the slice rack 600 in the storage mechanism can be manually or by a robot to be transferred to the receiving groove 200a of the loading component 200, and then transported to the slice removal station 300b through the conveying component 300, so that the material transfer component 100 can transfer the slice 700 to be scanned in the slice rack 600 to the stage 401 for scanning, and then transfer the scanned slice 700 from the stage 401 to the slice rack 600, so that the conveying component 300 can move the scanned slice 700 out.
[0067] When the conveying assembly 300 transfers the slice rack 600 containing the slices to be scanned 700 to the slice removal station 300b, the detection module 501 can detect the slices to be scanned 700 in the slice rack 600 to obtain the status information of the slices to be scanned 700, so that the slices to be scanned 700 in the slice rack 600 can be transferred to the stage 401 for scanning according to the status information, eliminating the tedious on-site monitoring of the operator and ensuring the working efficiency of the pathological slice scanner. However, the present application does not limit the situation where the slices to be scanned 700 are directly placed in the accommodating groove 200a, that is, the slices to be scanned 700 do not need to be stored in the slice rack 600, and then the slice rack 600 is placed in the accommodating groove 200a.
[0068] In an optional embodiment, the position of the material moving assembly 100 corresponds to the position of the slice removal station 300b, so that the material moving claw of the material moving assembly 100 can move along the vertical direction to the loading assembly 200 to take out the slice 700 in the loading assembly 200. No extra movements are required, the slice 700 can be efficiently transferred, and the structure of the entire pathology slice scanner can be simplified to reduce the size.
[0069] In an optional embodiment, if Figure 1 , Figure 3 and Figure 6 As shown, the material moving assembly 100 includes a material moving clamp 10 and a moving assembly. The material moving clamp 10 is installed on the frame through the moving assembly, so that the moving assembly can drive the material moving clamp 10 to move along at least one degree of freedom direction, which is used to realize the transfer of the slice 700 between the stage 401 and the loading assembly 200, thereby improving the automation level of the pathology slice scanner, saving labor, reducing labor costs, and improving work efficiency.
[0070] In an optional embodiment, the moving component includes a longitudinal component 20 and a vertical component 40. The material moving clamp 10 is connected to the vertical component 40 via the longitudinal component 20. The vertical component 40 is installed on the frame, so that the material moving clamp 10 can move along two degrees of freedom under the drive of the moving component to stably transfer the slices 700. The structure is reasonable and simple, and the degree of automation is high.
[0071] In an optional embodiment, the vertical assembly 40 is used to drive the material moving clamp 10 to move up and down in the vertical direction, so that the material moving clamp 10 can clamp the slice 700 on the loading assembly 200. When the material moving clamp 10 is moved downward by the vertical assembly 40, the material moving clamp 10 takes out the slice to be scanned from the loading and unloading assembly 200 from above, without requiring any extra movements, and can efficiently transfer the slice 700, and can also simplify the structure of the entire pathology slice scanner and reduce the size.
[0072] In an optional embodiment, the longitudinal component 20 is used to drive the material moving clamp 10 to move forward and backward in the horizontal direction. When the material moving clamp 10 is moved to the rear by the longitudinal component 20, the slice 700 to be scanned is placed on the stage 401, so that the image recognition component 402 above the stage 401 can read the information on the slice 700, and move the slice 700 to the detection position. The scanning component on the detection position can scan the slice 700 to obtain the pathological information on the slice, so that the identity information on the slice can be organically combined with the pathological information. It should be noted that the longitudinal component 20 and the vertical component 40 can be independent mechanisms, and this application does not limit them.
[0073] In an optional embodiment, the material transfer clamp 10 includes a clamp structure and a rotating structure 10c, and the clamp structure is connected to the moving component through the rotating structure 10c, so that the clamp structure can rotate around the rotation axis of the rotating structure 10c toward one side of the stage 401, so as to be able to move the slice 700 to be scanned in the slice rack 600 to the vertical stage 401 for scanning, thereby reducing the rotation angle of the clamp structure and eliminating the need for unnecessary movements; when the slice 700 is scanned, the clamp structure transfers the slice 700 from the stage 401 to the slice rack 600, efficiently transferring the slice 700, simplifying the structure of the entire pathology slice scanner, and reducing the size.
[0074] In an optional embodiment, the number of the material transfer jaws 10 is at least two, and at least two material transfer jaws 10 are spaced apart in a direction away from the moving component to alternately realize the slice transfer between the stage 401 and the loading component 200 .
[0075] In an optional embodiment, the moving assembly includes a transverse assembly 30, which is used to drive at least two material moving jaws 10 to move horizontally to the left and right. When one of the material moving jaws 10 takes out the scanned slice 700 from the stage 401, the transverse assembly 30 drives another material moving jaw 10 to place the slice to be scanned on the stage 401. During the slice scanning process, the material moving jaw 10 can put the scanned slice 700 back to the loading assembly 200, and then clamp the new slice 700 to be scanned, which greatly saves the waiting time during the clamping process of the slice 700 and speeds up the scanning speed. Among them, the transverse assembly 30 is used to realize the alignment of multiple material moving jaws 10 and the stage 401 during the switching process.
[0076] In an optional embodiment, the material transfer clamp 10 includes a first clamp 10a and a second clamp 10b, and the first clamp 10a and the second clamp 10b are arranged at intervals along the conveying direction of the conveying component, and are used to alternately realize the transfer of slices 700 between the stage 401 and the loading component 200, so that the first clamp 10a and the second clamp 10b can respectively take and place the slices 700 in the slice rack 600, and during the scanning process, one of the first clamp 10a and the second clamp 10b can clamp the new slice to be scanned, which is equivalent to a double-station design, which greatly saves the waiting time during the slice clamping process and speeds up the scanning speed.
[0077] Exemplarily, after the first clamp 10a and the second clamp 10b respectively clamp the slice 700 to be scanned in the slice rack 600, the first clamp 10a places the slice 700 to be scanned on the stage 401 for scanning. After the scanning of the slice 700 is completed, the first clamp 10a takes out the slice 700 on the stage 401, and the transverse component 30 drives the second clamp 10b to place the slice 700 to be scanned it on the stage 401 for scanning. Then the moving component drives the first clamp 10a to put the scanned slice 700 back into the slice rack 600 and replace it with a new slice 700 to be scanned, so that after the second clamp 10b clamps the scanned slice 700 on the stage 401, the first clamp 10a can place the new slice 700 to be scanned on the stage 401 for scanning. This alternating cycle greatly saves the waiting time in the slice clamping process and speeds up the scanning speed.
[0078] It should be noted that the first clamp 10a and the second clamp 10b can also simultaneously clamp the slice 700 to be scanned in the slice rack 600, and then alternately place the slice 700 to be scanned on the stage 401 for scanning, or the first clamp 10a and the second clamp 10b simultaneously place the slice 700 to be scanned on different workstations on the stage 401, and this application is not limited to this.
[0079] In an optional embodiment, a plurality of independent workstations are provided on the stage 401, and an image recognition component 402 is arranged above each workstation. The first clamp 10a and the second clamp 10b are used to realize the transfer of slices 700 between the loading component 200 and the plurality of workstations or between the plurality of workstations, so that the image recognition component 402 can read the identity information on the slice 700, and the array objective lens on each workstation can scan the slice 700 to shorten the waiting time of the first clamp 10a and the second clamp 10b during the scanning process of the slice 700, which not only improves the clamping efficiency of the first clamp 10a and the second clamp 10b, but also speeds up the scanning speed.
[0080] Exemplarily, there are two workstations, namely the first workstation and the second workstation, and both the first workstation and the second workstation can be moved separately along the conveying direction perpendicular to the conveying assembly 300 by the moving component 403. When the first clamp 10a and the second clamp 10b transfer the slice 700 in the slice rack 600 to the first workstation and the second workstation respectively, the image recognition component 402 can read the information of the slice 700 on the first workstation and the second workstation to obtain the identity information on the slice 700; then the moving component 403 moves the slice 700 on the first workstation and the second workstation to the detection position, and the array objective lens on the detection position can scan the slice 700. After the scanning of the slice 700 is completed, the first clamp 10a and the second clamp 10b transfer the slice 700 on the first workstation and the second workstation to the slice rack 600.
[0081] In an optional embodiment, the image recognition component 402 includes a supplementary light source and a camera, wherein the supplementary light source is located on at least one of the two sides of the camera. The camera is used to take a picture of the slice 700 before or after the slice 700 enters the scanning process to identify information related to the slice 700, including but not limited to QR codes, bar codes, handwritten words, pictures, etc., thereby realizing the digitization of the slice information and facilitating the staff to distinguish between different slices 700.
[0082] In an optional embodiment, the first jaw 10a and the second jaw 10b both have a clamping portion and a jaw driving member, the jaw driving member is connected to the rotating structure 10c, and the clamping portion is connected to the jaw driving member, and is used to abut against the slice 700 under the drive of the jaw driving member to grab the slice 700, so that the slice 700 can be transferred.
[0083] Exemplarily, the clamping portion includes a first clamping portion and a second clamping portion, which are arranged relative to each other and can move in relative or opposite directions under the drive of the clamping jaw driving member to achieve the clamping or release of the slice 70 by the material transfer clamp 10, so that the slice 700 can be transferred under the drive of the rotating structure 10c and the moving component, avoiding the slice 700 from being broken due to uneven force, ensuring the safe transportation of the slice and preventing fragments, easy operation, simple structure, and effectively improving the working efficiency of the pathology slice scanner.
[0084] It should be noted that the material transfer clamp 10 of the present application is not only used to transfer the slice 700 in the slice rack 600 to the stage 401 for scanning, but can also be used to transfer the slice 700 in other scenes. Its purpose is mainly to avoid the slice 700 from being broken due to uneven force during the transfer process, and to solve the problem of the slice 700 being broken by pushing the slice 700 into the stage 401 or other stations in the prior art. In addition, the material transfer clamp 10 can also only cooperate with one of the longitudinal component 20, the transverse component 30 and the vertical component 40. In other words, when the number of the material transfer clamp 10 is one, the transverse component 30 is not needed. The transverse component 30 is mainly used to achieve the alignment between multiple material transfer clamps 10 and the stage 401 or other stations, etc., and the present application does not limit it.
[0085] In an optional embodiment, if Figure 1 , Figure 5 and Figure 6 As shown, at least one of the first clamping portion and the second clamping portion is provided with two spaced apart clamping jaws, and the clamping portion with two clamping jaws is used to abut against the side of the slice 700 with the identity information, which can not only achieve multi-point contact with the slice 700 to form a stable clamp and ensure the stability of the slice 700 during the clamping process; but also play a avoiding role and will not block the identity information on the slice 700, so that after the slice 700 is placed on the stage 401, the image recognition component 402 can read the identity information.
[0086] Exemplarily, the first clamping portion is provided with two spaced-apart clamping jaws, and the second clamping portion is provided with only one clamping jaw. The first clamping portion abuts against the side of the slice 700 carrying the identity information, and the second clamping portion abuts against the other side of the slice 700, so that the three clamping jaws can make three-point contact with the slice 700 to achieve the clamping purpose, thereby enabling the slice 700 to be stably transferred without the need to use an expensive vacuum adsorption structure, thereby greatly reducing the design cost. The structural design is reasonable and can better cooperate with other mechanisms of the pathology slice scanner to quickly and accurately transfer the slice 700 to the scanning mechanism 400 for scanning, and / or remove the slice 700 that has been scanned from the scanning mechanism 400.
[0087] Exemplarily, the first clamping portion and the second clamping portion are each provided with two spaced-apart clamping jaws, one of which abuts against a side of the slice 700 carrying the identity information, and the other of which abuts against the other side of the slice 700, so that the four clamping jaws can make four-point contact with the slice 700 to achieve the purpose of clamping, thereby enabling the slice 700 to be stably transferred.
[0088] In an optional embodiment, the material transferring jaw 10 includes a connecting component 10d, and the second jaw 10b is connected to the first jaw 10a via the connecting component 10d, and the first jaw 10a or the second jaw 10b is connected to the rotating structure 10c to realize the connection between the first jaw 10a and the second jaw 10b and the rotating structure 10c, so that the rotating structure 10c can simultaneously drive the first jaw 10a and the second jaw 10b to rotate.
[0089] Exemplarily, the connecting assembly 10d includes a first connecting portion and a first connecting block, the first jaw 10a and the second jaw 10b are respectively connected to the two ends of the first connecting portion, and the first connecting block is connected to the same side of the first connecting portion, the first jaw 10a and the second jaw 10b to ensure the stability of the connection between the first jaw 10a and the second jaw 10b, and also to avoid interference between the first jaw 10a and the second jaw 10b when clamping the slice 700.
[0090] In an optional embodiment, the material transfer clamp 10 includes a first mounting block, a first fixed block and a first movable block, the first mounting block is fixedly connected to the first fixed block, the rotating structure 10c is installed on the longitudinal assembly 20 through the first fixed block, and the first movable block is connected to the output end of the rotating structure 10c, the first clamp 10a and the second clamp 10b, so that the rotating structure 10c can drive the first movable block, the first clamp 10a and the second clamp 10b to rotate relative to the first mounting block. In this embodiment, the first mounting block is provided with a first detection part, the first movable block is provided with a second detection part, and the second detection part cooperates with the first detection part to detect the rotation angle of the first clamp 10a and the second clamp 10b relative to the first fixed block.
[0091] In an optional embodiment, the longitudinal component 20 includes a longitudinal mounting seat, a longitudinal driving member, a longitudinal guide member and a longitudinal transmission member. The material moving jaw 10 is slidably mounted on the longitudinal mounting seat via the longitudinal guide member. The longitudinal driving member is transmission-connected to the material moving jaw 10 via the longitudinal transmission member. The longitudinal mounting seat is connected to the transverse component 30, so that the material moving jaw 10 can move along the longitudinal direction under the drive of the longitudinal driving member.
[0092] In an optional embodiment of the longitudinal guide member, the transverse component 30 includes a transverse mounting seat, a transverse driving member, a transverse guide member and a transverse transmission member. The longitudinal component 20 is slidably mounted on the transverse mounting seat through the transverse guide member. The transverse driving member is transmission-connected to the longitudinal component 20 through the transverse transmission member. The transverse mounting seat is connected to the vertical component 40, so that the material moving clamp 10 can move in the transverse direction under the drive of the transverse driving member.
[0093] In an optional embodiment of the transverse guide member, the vertical component 40 includes a vertical connecting seat, a vertical driving member and a vertical transmission member. The vertical driving member is connected to the transverse component 30 through the vertical transmission member. The vertical driving member and the vertical transmission member are installed on the frame of the pathology slice scanner through the vertical connecting seat.
[0094] In an optional embodiment, the vertical assembly 40 includes a vertical mounting seat, and the horizontal assembly 30 is connected to the moving seat via the vertical mounting seat.
[0095] In an optional embodiment, the vertical component 40 includes a vertical support base, and the vertical connecting base is installed on the frame of the pathology slice scanner through the vertical support base.
[0096] In an optional embodiment, if Figure 1 , Figure 7 and Figure 8 As shown, the loading assembly 200 includes a loading seat 201 and a positioning structure 202 for limiting the position of the slice rack 600. The loading seat is connected to the conveying assembly 300, and the positioning structure is arranged on the loading seat.
[0097] Exemplarily, the positioning assembly 202 includes a propulsion structure and a positioning part, and the positioning part is connected to the propulsion structure, so that the positioning part can abut against the side wall of the slice frame 600 under the drive of the propulsion structure to form a limit. Among them, the accommodating groove 200a is formed in the loading seat 201, the propulsion structure is fixed on the loading seat 201, and the positioning part is movably installed in the accommodating groove 200a and can move along the first direction to limit the slice frame 600 in the accommodating groove 200a, realize the compression of the slice frame 600, avoid the slice frame 600 from moving relative to the loading seat 201, and prevent the slice frame 600 from shaking during the transportation process, thereby affecting the detection result of the detection assembly 500. The whole structure is simple and reliable, and easy to operate, which improves the versatility of the pathology slice scanner.
[0098] In an optional embodiment, the propulsion structure includes a driving member and a transmission member, the driving member is installed on the loading seat 201, and the positioning part is connected to the driving member through the transmission member, so that the positioning part can abut against the slice rack 600 under the drive of the driving member to form a limit, so as to ensure that the slice rack 600 can be firmly placed in the receiving groove 200a, especially in the process of transporting the loading component 200 by the conveying component 300, the slice 700 is easily damaged due to sliding, collision, etc. of the slice rack 600 in the receiving groove 200a.
[0099] In an optional embodiment, the positioning assembly 202 includes a guide rod 202c and a fixing member, and the driving member is fixed to the loading seat through the fixing member. One end of the guide rod 202c is fixedly connected to the positioning part, and the other end of the guide rod 202c is slidably connected to the fixing member, so that the positioning part can combine with the guide rod 202c to evenly apply pressure on the slice rack 600. The guide rod 202c not only limits the sliding trajectory of the positioning part, making it less likely for the positioning part to be displaced during the sliding process; it can also improve the stability of the positioning part sliding in the accommodating groove 200a, and improve the effect of pressing against the slice rack 600.
[0100] In an optional embodiment, the positioning portion has a connecting portion and a buffer portion, the propulsion structure is connected to the connecting portion, and the buffer portion is arranged on the side of the connecting portion facing the slice rack 600. When the positioning portion moves toward the slice rack 600, the buffer portion can reduce the impact force of the positioning portion on the slice rack 600, thereby protecting the slices 700 in the slice rack 600.
[0101] In an optional embodiment, the positioning portion includes a limiting plate 202e, and a limiting groove is provided on the loading seat 201. One end of the limiting plate 202e is fixedly connected to the positioning portion, and the other end of the guide plate is movably installed in the guide groove, so that the driving member can drive the positioning portion to move along the guide direction of the guide rod 202c, ensuring that the positioning portion is not easily displaced during the movement.
[0102] In an optional embodiment, the loading seat 201 includes a base, which is tilted toward a side away from the stage 401, so that the slices 700 of the slice rack 600 placed on the loading seat 201 can be tilted toward the side away from the stage. This not only prevents the slices 700 in the slice rack 200 from tilting toward the rear side, that is, the inner side of the conveying component 20 when transferring the loading component 10, but also prevents the slices 700 from being disturbed by the internal structure of the pathological slice scanner during the movement, thereby ensuring the safety of the slices 700; at the same time, it can also cooperate with the material moving component 100 so that the material moving clamp 10 can quickly clamp the slice 700, and then rotate toward one side of the stage, so that the identity information on the slice 700 can face the outside of the stage, that is, the QR code or handwritten code information on the slice 700, so that the image recognition component 402 on the stage can read the QR code or handwritten code information, thereby reducing the angle at which the slice 700 needs to rotate.
[0103] In an optional embodiment, the inclination angle of the base is between 1 degree and 10 degrees, which can ensure that the slice 700 is tilted in the slice rack 600 and facilitate the removal of the slice 700 from the slice rack 600.
[0104] In an optional embodiment, the base includes a first base 2011 and a second base 2012, and the first base 2011 and the second base 2012 are spaced apart along the height direction of the loading seat 201. The receiving groove 200a is formed at the upper end of the second base 2012, and the limiting groove is formed at the lower end of the second base 2012.
[0105] In an optional embodiment, a portion of the positioning portion is disposed above the second base 2012 , and another portion of the positioning portion is disposed below the second base 2012 .
[0106] In an optional embodiment, the loading seat 201 includes a first limiting portion and a second limiting portion spaced apart along a second direction, the second direction being perpendicular to the first direction, and the first limiting portion cooperates with the second limiting portion to limit the position of the slice rack 600 in the second direction, so that the slice rack 600 can be limited in the first direction and the second direction of the accommodating groove 200a, thereby being firmly placed in the accommodating groove 200a.
[0107] It should be noted that the first direction refers to the length direction of the slice rack 600, and the second direction refers to the width direction of the slice rack 600, that is, the positioning portion is used to limit the position of the slice rack 600 in the length direction, so that the accommodating groove 200a can adapt to slice racks 600 of different lengths; and the first limiting portion cooperates with the second limiting portion to limit the position of the slice rack 600 in the width direction, so that the accommodating groove 200a can adapt to slice racks 600 of different widths. In addition, the present application can also only limit the position of the slice rack 600 in the length direction or the width direction, or the first direction refers to the width direction of the slice rack 600, and the second direction refers to the length direction of the slice rack 600, and the present application does not limit it.
[0108] In an optional embodiment, waist grooves are provided on both sides of the loading seat 201 to facilitate a human hand or a mechanical claw to clamp the slice rack 600 from the loading seat 201 .
[0109] Exemplarily, the waist groove includes a first waist groove and a second waist groove, the first waist groove is formed on the first limiting portion, the second waist groove is formed on the second limiting portion, and the position of the first waist groove corresponds to the position of the second waist groove, so as to facilitate human hands or mechanical claws to clamp the slice rack 600 from the loading seat 201.
[0110] In an optional embodiment, the loading seat 201 also includes a front baffle, the first limiting portion is one of the side panels of the loading seat 201, the second limiting portion is the other side panel of the loading seat 201, the front baffle is connected to one end of the two side panels, and the fixing member is connected to the other end of the two side panels, so that the front baffle, the fixing member and the two side panels can be jointly arranged to form the above-mentioned accommodating groove 200a.
[0111] The first limiting part is fixedly connected to the front baffle, and the second limiting part is movably connected to the front baffle. When the slice rack 600 is placed in the receiving groove 200a, the positioning part moves toward one side of the front baffle to cooperate with the front baffle to limit the slice rack 600 in the length direction, and the second limiting part moves toward one side of the first limiting part, or the relative position between the second limiting part and the first limiting part has been adjusted before the slice rack 600 is placed in the receiving groove, so that the second limiting part and the first limiting part, the positioning part and the front baffle can jointly position the slice rack, and the positioning reference of the slice rack 600 in the receiving groove 200a is determined by the fixed connection between the first limiting part and the front baffle. Therefore, this can not only meet the requirements of compatible storage of slice racks 600 of different sizes, but also facilitate the positioning of the slice rack 600 to ensure the accuracy of its relative position, and facilitate the subsequent removal of a single slice from the slice rack 600.
[0112] In an optional embodiment, the loading base 201 includes an elastic structure and a slide rail structure, and the second limiting portion is slidably installed on the second side through the slide rail structure. The two ends of the elastic structure are respectively abutted against the first limiting portion and the second limiting portion, so that the elastic structure always maintains an elastic force to drive the second limiting portion to move in a direction away from the first limiting portion; when the second limiting portion needs to move toward the direction of the first limiting portion, the distance between the second limiting portion and the base in the second direction can be adjusted by the locking member to overcome the elastic force of the elastic structure.
[0113] In an optional embodiment, the loading assembly 200 further includes a detection member, which is disposed on the loading seat 201 and is used to detect the slice rack 600 placed in the receiving groove 200a to determine whether the slice rack 600 is placed in the receiving groove 200a.
[0114] In an optional embodiment, the conveying assembly 300 includes a conveying seat 301, a conveying track 302 and a conveying motor 303. The loading assembly 200 is slidably mounted on the conveying seat 301 via the conveying track 302. The conveying motor 303 is used to drive the loading assembly 200 to reciprocate along the conveying track 302 between the slicing feeding station 300a and the slicing removing station 300b to realize the conveyance of the loading assembly 200.
[0115] In an optional embodiment, the loading assembly 200 reciprocates along the length direction of the conveying track 302, and the length direction of the loading seat 301 is perpendicular to the length direction of the conveying track 302, so that the conveying assembly 300 can transport the loading assembly 200 from the slicing delivery station to the slicing removal station. At this time, the length direction of the slicing rack 600 is set in a direction perpendicular to the conveying track 302, so that the material moving assembly 100 can move the slices in the slicing rack 600.
[0116] In an optional embodiment, the conveying track 302 includes a conveying slide rail and a conveying slider cooperating with the conveying slide rail, the loading assembly 200 is connected to the conveying slider, and the length direction of the loading seat 201 is perpendicular to the length direction of the conveying seat 301, and the conveying slide rail is arranged along the length direction of the conveying seat 301.
[0117] In an optional embodiment, the conveying assembly 300 includes a limiting structure 304, which is arranged on the slicing removal station. When the conveying assembly 300 conveys the loading assembly 200 to the slicing removal station, the limiting structure 304 can limit the second limiting part and push the second limiting part to move in the direction of the first limiting part, so that the slicing rack 600 can be positioned in the receiving groove 200a. The minimum distance between the second limiting part and the first limiting part is adapted to the width of the base, thereby limiting the moving distance of the second limiting part. When the conveying assembly 300 conveys the loading assembly 200 to the slicing delivery station, the limiting structure 304 releases the limiting of the second limiting part, and the second limiting part moves in the direction away from the first limiting part, releasing the limiting and positioning effect on the slicing rack 600, so as to facilitate the slicing rack to be taken out from the loading assembly.
[0118] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection. It can be a mechanical connection or an electrical connection. It can be directly connected or indirectly connected through an intermediate medium. It can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.
[0119] In the present application, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.
[0120] The disclosure above provides many different embodiments or examples to realize the different structures of the present application. In order to simplify the disclosure of the present application, the parts and settings of specific examples are described above. Of course, they are only examples, and the purpose is not to limit the present application. In addition, the present application can repeat reference numbers and / or reference letters in different examples, and this repetition is for the purpose of simplification and clarity, which itself does not indicate the relationship between the various embodiments and / or settings discussed. In addition, the various specific processes and material examples provided by the present application, but those of ordinary skill in the art can be aware of the application of other processes and / or the use of other materials.
[0121] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "illustrative embodiments", "examples", "specific examples", or "some examples" means that the specific features, structures, materials, or characteristics described in conjunction with the embodiments or examples are included in at least one embodiment or example of the present application. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described may be combined in any one or more embodiments or examples in a suitable manner.
Claims
1. A pathological slice scanner, characterized in that: Including loading and unloading mechanism, scanning mechanism and frame, The scanning mechanism comprises a stage for placing the slices and a scanning component for scanning the slices; The loading and unloading mechanism includes a material moving component, a conveying component and a loading component. The stage, the scanning component, the material moving component, the conveying component and the loading component are all arranged on the frame. The material moving component is used to move the slices on the loading component to the stage and / or move the slices scanned on the stage to the loading component. The conveying component is used to transport the slices on the loading component. Wherein, the loading and unloading mechanism further includes a detection component for detecting status information of the slices placed in the loading component, so that the material moving component can move the slices in the loading component according to the status information detected by the detection component.
2. The scanner according to claim 1, characterized in that The detection assembly comprises a detection module and a detection bracket, the detection module is mounted on the frame through the detection bracket, and the conveying assembly is located below the detection module; and / or, The scanning mechanism also includes an image recognition component for reading the identity information on the slice.
3. The scanner according to claim 2, characterized in that: The conveying assembly has a slice feeding station and a slice removing station, the detection module is arranged above the slice feeding station, and the position of the slice removing station corresponds to the position of the loading platform.
4. The scanner according to claim 3, characterized in that: The position of the material moving assembly corresponds to the position of the slice moving out station, so that the material moving claw of the material moving assembly can move to the loading assembly along the vertical direction to take out the slices in the loading assembly.
5. The scanner according to claim 1, characterized in that: The material moving assembly includes a material moving claw and a moving assembly, and the material moving claw is installed on the frame through the moving assembly, so that the moving assembly can drive the material moving claw to move along at least one degree of freedom direction, so as to realize the transfer of the slice between the stage and the loading assembly.
6. The scanner according to claim 5, characterized in that: The conveying assembly has a slice feeding station and a slice removing station, the detection assembly is arranged at the slice feeding station, the moving assembly includes a vertical assembly, and the vertical assembly is used to drive the material moving clamp to move up and down in the vertical direction. When the material moving clamp is moved downward by the vertical component, the material moving clamp takes out the slice to be scanned from the loading and unloading component from above.
7. The scanner according to claim 5 or 6, characterized in that: The moving assembly includes a longitudinal assembly, and the longitudinal assembly is used to drive the material moving clamp to move forward and backward in a horizontal direction. When the material moving clamp is moved to the rear by the longitudinal assembly, the slice to be scanned is placed on the stage.
8. The scanner according to claim 5, characterized in that: The material transfer clamp comprises a clamp structure and a rotating structure, wherein the clamp structure is connected to the moving assembly via the rotating structure, so that the clamp structure can rotate around the rotating axis of the rotating structure toward one side of the stage; and / or, The material transfer clamp comprises a first clamp and a second clamp, wherein the first clamp and the second clamp are arranged at intervals along the conveying direction of the conveying assembly, and are used to alternately realize the slice transfer between the stage and the loading assembly.
9. The scanner according to claim 8, characterized in that The moving component also includes a transverse component, which is used to drive the first clamp and the second clamp to move left and right in the horizontal direction. When the first clamp takes the scanned slice out of the stage, the transverse component drives the second clamp to place the slice to be scanned onto the stage.
10. The scanner according to claim 1, characterized in that: The loading assembly includes a loading seat for placing a slice rack and a positioning assembly for limiting the position of the slice rack. The loading seat is connected to the conveying assembly. The positioning assembly is arranged on the loading seat for limiting the slice rack in the accommodating groove.
11. The scanner according to claim 10, characterized in that The conveying assembly comprises a conveying track, the loading assembly reciprocates along the length direction of the conveying track, and the length direction of the loading seat is perpendicular to the length direction of the conveying track; and / or, The loading seat comprises a base, and the base is tilted toward a side away from the stage, so that the slices of the slice rack placed on the loading seat can be tilted toward the side away from the stage.
12. The scanner according to claim 11, characterized in that The inclination angle of the base is between 1 degree and 10 degrees; and / or waist grooves are provided on both sides of the loading seat.