Cosmetic containing crude salt extracting solution and preparation method thereof

Abstract

The invention discloses a cosmetic containing a crude salt extracting solution and a preparation method of the cosmetic, and belongs to the field of cosmetics. By utilizing a supersaturation technology and an evaporative crystallization method, salts such as sodium chloride and the like are separated out from Shanxi Yuncheng salt lake crude salt, the sodium salt concentration is reduced, trace elements are enriched, and a crude salt extracting solution is obtained; on the basis, cosmetics with moisturizing performance, skin barrier repairing function and skin whitening and brightening effects are prepared on the basis of the crude salt extracting solution, and new application of the crude salt extracting solution in the field of cosmetics is achieved.

Description

Technical Field

[0001] The invention relates to a cosmetic containing a crude salt extract and a preparation method thereof, belonging to the field of cosmetics. Background Art

[0002] Factors such as increased environmental pollution, enhanced solar radiation, increased life stress and decreased immunity have led to an increase in the number of people with sensitive skin. The occurrence of sensitive skin is related to damaged skin barrier, increased immune inflammatory response and neurovascular response.

[0003] Modern scientific research has found that the minerals and trace elements in hot spring water have skin care effects such as repairing skin barrier, anti-inflammatory, soothing and improving skin aging. Yang Lihua et al. (Yang Lihua, Fu Xiaofeng, Fu Yingmei, et al. Transformation effect of selenium-rich hot spring water immersion on hypertrophic burn scars [J]. Chinese Journal of Tissue Engineering Research and Clinical Rehabilitation, 2008 (27): 5309-5312.) proved through control experiments that selenium-rich hot spring water immersion treatment can clean burn wounds, inhibit scar hyperplasia, and promote scar softening, and can be used as an auxiliary treatment for post-burn scar hyperplasia. Zhang Ningping et al. (Zhang Ningping, Wang Zhonghua, Pan Zhiqiang, et al. Characteristics and health-care effects of Tengchong hot spring hydrotherapy [J]. Southwest Military Medicine, 2021, 23(02): 173-175.) found that the weakly alkaline water of Tengchong hot spring hydrotherapy can neutralize the acidity of human skin and maintain the pH balance of the skin; at the same time, it softens the stratum corneum, making the skin smooth and elastic; it can also soften scars on the wound surface and promote their maturity and shedding. These methods mainly use the minerals and trace elements in hot spring water for skin care, but they lack specificity and standardization, and hot spring water resources are limited.

[0004] The salt from Yuncheng Salt Lake in Shanxi Province is large in size, white in color, pure in texture, and rich in more than 30 minerals and trace elements such as potassium, sodium, calcium, magnesium, phosphorus, and chlorine. It is a high-quality, natural beauty product. However, there is no literature that mentions that crude salt extract can be used in the cosmetics field.

[0005] Therefore, the preparation of cosmetics based on crude salt from Yuncheng Salt Lake has broad application prospects. Summary of the invention

[0006] [Technical issues]

[0007] Most mineral skin care waters for sensitive skin groups use minerals and trace elements in hot spring water to repair the skin barrier, reduce inflammation and relieve pain. They lack specificity and standardization, and hot spring water resources are limited.

[0008] At present, there is no literature mentioning that crude salt extract can be used in the cosmetic field.

[0009] [Technical solution]

[0010] To solve the above problems, the present invention utilizes supersaturation technology and evaporation crystallization methods to precipitate salts such as sodium chloride from the crude salt of Yuncheng Salt Lake in Shanxi, reduce the concentration of sodium salt, enrich trace elements, and obtain a crude salt extract; on this basis, cosmetics with moisturizing properties, skin barrier repair function, and skin whitening and brightening effects are prepared based on the crude salt extract, realizing a new application of the crude salt extract in the field of cosmetics.

[0011] The first object of the present invention is to provide a cosmetic containing a crude salt extract, wherein the mass percentage of the crude salt extract in the cosmetic is 0.01 to 12.5%.

[0012] As an embodiment of the present invention, cosmetics include mineral skin care water, essence, essence milk, face cream and the like.

[0013] As an embodiment of the present invention, the crude salt extract is a crude salt extract from Yuncheng Salt Lake in Shanxi.

[0014] As an embodiment of the present invention, the preparation method of the crude salt extract is as follows:

[0015] Dissolve the crude salt in water, filter through a membrane, and take the permeate for desalination to obtain a crude salt extract;

[0016] Among them, the mass ratio of crude salt to water is 1:3-5;

[0017] The pore size of the membrane in membrane filtration is 0.22 μm;

[0018] Desalination is done by rotary evaporation at 40-85°C and 50-150 rpm;

[0019] The ratio of the volume after desalting to the volume before desalting is 1:5-10;

[0020] After desalination, filtration and dilution are required. The pore size of the membrane used for filtration is 0.22μm, and the dilution multiple is 1 to 3 times.

[0021] As an embodiment of the present invention, the crude salt extract can be diluted as needed when used in cosmetics, with the dilution multiple being 8-1000 times.

[0022] The second object of the present invention is to provide a mineralized skin care water containing a crude salt extract, which uses a crude salt extract; wherein the crude salt extract is diluted with water, and the mass concentration of the crude salt extract dilution in the mineralized skin care water is 0.01 to 12.5%.

[0023] As an embodiment of the present invention, the preparation method of the crude salt extract is as follows:

[0024] Dissolve the crude salt in water, filter through a membrane, and take the permeate for desalination to obtain a crude salt extract;

[0025] Among them, the mass ratio of crude salt to water is 1:3-5;

[0026] The pore size of the membrane in membrane filtration is 0.22 μm;

[0027] Desalination is done by rotary evaporation at 40-85°C and 50-150 rpm;

[0028] The ratio of the volume after desalting to the volume before desalting is 1:5-10;

[0029] After desalination, filtration and dilution are required. The pore size of the membrane used for filtration is 0.22μm, and the dilution multiple is 1 to 3 times.

[0030] As an embodiment of the present invention, the ingredients of the mineralized skin care water include crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia japonica flower extract, Portulaca oleracea extract, lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, ethylhexylglycerin, and deionized water;

[0031] Among them, crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia japonica flower extract, Portulaca oleracea extract The mass percentages of OLERACEA extract, lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, and ethylhexylglycerin in cosmetics are (1-12.5)%: (0.1-6)%: (0.01-1)%: (0.01-0.5)%: (0.01-0.5)%: (0.1-0.5)%: (0.5-5)%: (0.01-0.2)%: (0.01-0. 2)%:(0.01-0.2)%:(0.01-0.2)%:(0.01-0.2)%:(0.01-0.2)%:(0.01-0.2)%:(0.001-0.1)%:(0.001-0.1)%:(0.1-10)%:(0.05-5)%:(0.01-1)%:(0.01-1)%:(0.1-5)%:(0.1-5)%:(0.1-5)%; make up to 100% with deionized water.

[0032] As an embodiment of the present invention, the dilution factor of the crude salt extract is more than 8 times, preferably 8 to 16 times.

[0033] The third object of the present invention is to provide a method for preparing a mineralized skin care water containing a crude salt extract, comprising the following steps:

[0034] The crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia japonica flower extract, Portulaca oleracea extract, lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, ethylhexylglycerin and deionized water are uniformly mixed to obtain a mineralized skin care water.

[0035] The fourth object of the present invention is to provide an essence, which uses a crude salt extract; wherein the mass concentration of the crude salt extract in the essence is 0.01-12.5%.

[0036] As an embodiment of the present invention, the preparation method of the crude salt extract is as follows:

[0037] Dissolve the crude salt in water, filter through a membrane, and take the permeate for desalination to obtain a crude salt extract;

[0038] Among them, the mass ratio of crude salt to water is 1:3-5;

[0039] The pore size of the membrane in membrane filtration is 0.22 μm;

[0040] Desalination is done by rotary evaporation at 40-85°C and 50-150 rpm;

[0041] The ratio of the volume after desalting to the volume before desalting is 1:5-10;

[0042] After desalination, filtration and dilution are required. The pore size of the membrane used for filtration is 0.22μm, and the dilution multiple is 1 to 3 times.

[0043] As an embodiment of the present invention, the dilution factor of the crude salt extract is more than 8 times, preferably 8 to 16 times.

[0044] [Beneficial Effects]

[0045] 1. The present invention adopts crude salt from Shanxi Yuncheng Salt Lake as raw material, and obtains crude salt extract through a specific process, showing regional characteristics and raw material advantages.

[0046] 2. The present invention evaluates the irritation and safety of the crude salt extract by the chicken embryo chorioallantoic membrane (CAM) test to ensure the safety and effectiveness of the skin care water: after adding the crude salt extract and its 2-fold and 4-fold dilutions, the chicken embryo blood vessels show bleeding symptoms to varying degrees at 30s, 30s and 150s respectively; and when the crude salt extract diluted 8 times is added dropwise, the chicken embryo blood vessels have no obvious changes, which indicates that the crude salt extract at this concentration is safe and non-irritating. Therefore, the present invention adopts the crude salt extract diluted 8 times and above as the appropriate concentration.

[0047] 3. In the crude salt extract prepared by the present invention, calcium and magnesium ions are enriched by 2.3 and 2.5 times respectively, and strontium ions are enriched by up to 6.3 times. Calcium and magnesium ions, especially strontium ions, have the dual effects of soothing nerves and relieving inflammation on the skin.

[0048] 4. The skin care water prepared by the present invention has excellent moisturizing properties, and the data at each time point are significantly different from the basic data. Transepidermal water loss shows a significant difference at 8 hours, proving that the present invention has a certain skin barrier repair ability, and the addition of various plant extracts, niacinamide and collagen makes the present invention have a good whitening and lightening effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0049] Figure 1 From left to right are crude salt, crude salt solution before treatment, and salts removed during the desalination process.

[0050] Figure 2 These are the experimental results of the positive control group in Example 1 (CAM conditions at four time points: 0s, 30s, 150s, and 300s from left to right).

[0051] Figure 3 These are the experimental results of the negative control group in Example 1 (CAM conditions at four time points, 0s, 30s, 150s, and 300s, from left to right).

[0052] Figure 4 These are the experimental results of the crude salt extract groups with different dilution multiples in Example 1 (CAM conditions at four time points: 0s, 30s, 150s, and 300s from left to right).

[0053] Figure 5 This is a physical picture of the mineral skin care water prepared in Example 2.

[0054] Figure 6 These are the experimental results of the irritation of the mineral skin care water in Example 2 (from left to right, the CAM conditions at four time points: 0s, 30s, 150s, and 300s).

[0055] Figure 7This is a graph showing the change in skin moisture content of the mineral skin care water in Example 2.

[0056] Figure 8 This is a graph showing the changes in transepidermal water loss of the mineral skin care water in Example 2.

[0057] Fig. 9 This is a diagram showing the skin color change of the mineral skin care water in Example 2.

[0058] Fig.10 This is a graph showing the change in skin glossiness of the mineral skin care water in Example 2.

[0059] Fig.11 These are the test results of the skin moisture content (A), transepidermal water loss (B), skin color (C) and glossiness (D) of the skin care water in Comparative Example 1.

[0060] Fig.12 These are the test results of the skin moisture content (A), transepidermal water loss (B), skin color (C) and glossiness (D) of the skin care water in Comparative Example 2.

[0061] Fig.13 These are the test results of the skin moisture content (A), transepidermal water loss (B), skin color (C) and glossiness (D) of the skin care water in Comparative Example 3. DETAILED DESCRIPTION

[0062] The preferred embodiments of the present invention are described below. It should be understood that the embodiments are for better explaining the present invention and are not used to limit the present invention.

[0063] Test method:

[0064] 1. Test of ion types and quantities in crude salt:

[0065] (1) Inductively coupled plasma mass spectrometer: ICAP TQ, Thermo Fisher Scientific Inc.

[0066] (2) Ion chromatograph: D150, Qingdao Shenghan Chromatography Technology Co., Ltd.

[0067] 2. Test of skin care water efficacy:

[0068] (1) Skin moisture content:

[0069] The skin tester and Corneometer CM825 stratum corneum moisture content test probe are used to measure the capacitance change of the stratum corneum to reflect its water content. The principle is that the dielectric constants of water and other substances are significantly different.

[0070] Use a moisture tester to measure the water content of the stratum corneum on the left and right cheeks respectively, and take the average value of the measurements three times.

[0071] (2) Transepidermal water loss (TEWL):

[0072] Transepidermal water loss is a measure of the amount of water that passes from the body through the epidermal skin into the surrounding atmosphere by the processes of diffusion and evaporation.

[0073] The test used a transepidermal water loss meter to measure the transepidermal water loss of the left and right faces respectively, and the average value was taken after 20 measurements.

[0074] (3) Skin color:

[0075] The principle of the probe to measure skin color is mainly based on the principle of spectral absorption and reflection.

[0076] The probe emits white LED light in a ring shape, which is scattered omnidirectionally inside the probe, penetrating the skin surface and scattering inside the skin. The key is that only the light reflected back to the probe is captured by its built-in XYZ sensor, which is designed to perform accurate testing through the skin color detection probe.

[0077] The test uses a skin color test probe to measure the skin color of the left and right sides of the face respectively, and the average value is taken after three measurements.

[0078] (4) Glossiness;

[0079] The glossiness of the skin surface is reflected by the direct reflection and scattering of light hitting the skin surface.

[0080] The test uses a gloss probe to measure the gloss of the left and right faces respectively, and the average value is taken after three measurements.

[0081] (5) Data statistical analysis:

[0082] IBM SPSS Statistics 23.0 was used for data statistical analysis. Paired t-test was performed for data with normal distribution (normality test P value>0.05), otherwise paired rank sum test was used. P<0.05 was considered significant, with *p<0.05, **p<0.01, ***p<0.001.

[0083] 3. Irritation test:

[0084] (1) Sample preparation

[0085] Positive control: 0.1 mol / L NaOH solution, 40 mg NaOH dissolved in 10 mL deionized water;

[0086] Negative control: 0.9% NaCl solution, 90 mg NaCl dissolved in 10 mL deionized water.

[0087] (2) Crude salt sample

[0088] Take the crude salt extract and dilute it 2, 4, 8, and 16 times in sequence for later use;

[0089] (3) Preparation of chick chorioallantoic membrane (CAM)

[0090] Purchase 0-day-old chicken embryos, 50-60g;

[0091] Incubator temperature: 37.5±0.5℃, relative humidity: 55%-70%;

[0092] During the incubation process, the chicks were turned over twice a day, and the development status of the chick embryos was checked at 5 days of age.

[0093] At 6 days, peel off the eggshell to expose the white egg membrane;

[0094] Use a pipette to add 200 μL of 0.9% NaCl solution to moisten the egg membrane, carefully remove the inner membrane with forceps, making sure that the vascular membrane is not damaged, and pour out the NaCl solution.

[0095] (4) Sample testing

[0096] Take 0.1 mL of the sample and drop it evenly on the surface of CAM, observe the reaction of CAM, and take photos to record the reaction degree at 0s, 30s, 150s, and 300s.

[0097] The same operation procedures were used for positive and negative controls.

[0098] (5) Data analysis

[0099] The time and degree of reaction of each detection endpoint were recorded.

[0100] Example 1

[0101] The method for preparing crude salt extract from Yuncheng Salt Lake in Shanxi Province comprises the following steps:

[0102] Weigh 15g of crude salt from Yuncheng Salt Lake, Shanxi Province, add 45mL of ultrapure water to dissolve it completely, filter it with a 0.22μm filter membrane, and adjust the volume to 50mL to obtain the crude salt permeate;

[0103] Transfer 45 mL of crude salt permeate to a 250 mL single-necked flask and desalt to 5 mL by rotary evaporation crystallization in an 80°C water bath at 100 rpm; take out, filter with a 0.22 μm filter membrane, and dilute to 10 mL to obtain a crude salt extract.

[0104] The obtained crude salt permeate and crude salt extract (before and after crude salt desalination) were subjected to performance tests, and the test results are as follows:

[0105] (1) Test of metal ion content:

[0106] Table 1 Total amount of cations before and after desalination of crude salt

[0107] ion Before treatment (mg) After treatment (mg) <![CDATA[Ca 2+ ]]> 8.20 2.99 <![CDATA[Mg 2+ ]]> 118 46.5 <![CDATA[Na + ]]> 3250 476 <![CDATA[K + ]]> 4.60 1.89 <![CDATA[Mn 2+ ]]> <![CDATA[3.54×10 -3 ]]> <![CDATA[5.93×10 -4 ]]> <![CDATA[Zn 2+ ]]> <![CDATA[5.25×10 -4 ]]> <![CDATA[6.33×10 -5 ]]> <![CDATA[Se 2+ ]]> <![CDATA[1.2×10 -5 ]]> <![CDATA[1.4×10 -6 ]]> <![CDATA[Sr 2+ ]]> <![CDATA[2.14×10 -2 ]]> <![CDATA[2.04×10 -2 ]]>

[0108] It can be seen from Table 1 that most of the cations are reduced to varying degrees through desalination. + The Ca 2+ Mg 2+ , K + and Mn 2+ decreased by 2-3 times, while Sr 2+ There was basically no decline.

[0109] Table 2 Cation content of crude salt before and after desalination

[0110] ion Before treatment (mg / g) After treatment (mg / g) Enrichment multiple <![CDATA[Ca 2+ ]]> 0.608 1.40 2.3 <![CDATA[Mg 2+ ]]> 8.75 21.7 2.5 <![CDATA[Na + ]]> 241 222 0.92 <![CDATA[K + ]]> 0.341 0.885 2.6 <![CDATA[Mn 2+ ]]> <![CDATA[2.62×10 -4 ]]> <![CDATA[2.78×10 -4 ]]> 1.1 <![CDATA[Zn 2+ ]]> <![CDATA[3.89×10 -5 ]]> <![CDATA[2.96×10 -5 ]]> 0.76 <![CDATA[Se 2+ ]]> <![CDATA[8.9×10 -7 ]]> <![CDATA[6.5×10 -7 ]]> 0.73 <![CDATA[Sr 2+ ]]> <![CDATA[1.59×10 -3 ]]> <![CDATA[9.52×10 -3 ]]> 6.3

[0111] It can be seen from Table 2 that through desalination, Ca 2+ Mg 2+ , K + enriched 2-3 times, while Sr 2+ Enriched 6.3 times.

[0112] Table 3 Total amount of anions before and after crude salt desalination

[0113] ion Before treatment (mg) After treatment (mg) <![CDATA[Cl - ]]> <![CDATA[7.43×10 3 ]]> 971 <![CDATA[SO4 2- ]]> 380 116 <![CDATA[CO3 2- ]]> 0.225 0.05 <![CDATA[HCO3 - ]]> 40.5 9.59

[0114] Table 4 Anion content of crude salt before and after desalination

[0115] ion Before treatment (mg / g) After treatment (mg / g) Enrichment multiple <![CDATA[Cl - ]]> 550 454 0.82 <![CDATA[SO4 2- ]]> 28.2 54.2 1.9 <![CDATA[CO3 2- ]]> 0.0167 0.0234 1.4 <![CDATA[HCO3 - ]]> 3.00 4.48 1.5

[0116] It can be seen from Table 3 and Table 4 that most of the anions in crude salt are Cl - , a small part is SO4 2- 、HCO3 - It can be inferred that the crude salt is mostly sodium chloride, and some is sulfate.

[0117] Combined with Table 1, it can be seen that in the desalination process, most of the sodium chloride is removed; at the same time, in the precipitation crystallization process, Ca 2+ Mg 2+ , K + and Mn 2+ The trace elements are absorbed or contained by sodium chloride crystals, resulting in the loss of some trace elements. However, by analyzing the cation content of each gram of crude salt before and after treatment, it can be found that Na + , Ca 2+ Mg 2+ , K + and Mn 2+Plasma showed different degrees of improvement, and Sr 2+ The ion was enriched 6.3 times.

[0118] (2) Irritation test:

[0119] The crude salt extract was directly tested for ion content without any dilution, and the results are as follows:

[0120] Table 5 Ion content of crude salt extract

[0121] ion Ion concentration (mg / mL) <![CDATA[Ca 2+ ]]> 0.299 <![CDATA[Mg 2+ ]]> 4.65 <![CDATA[Na + ]]> 47.6 <![CDATA[K + ]]> 0.189 <![CDATA[Mn 2+ ]]> <![CDATA[5.93×10 -5 ]]> <![CDATA[Zn 2+ ]]> <![CDATA[6.33×10 -6 ]]> <![CDATA[Se 2+ ]]> <![CDATA[1.40×10 -7 ]]> <![CDATA[Sr 2+ ]]> <![CDATA[2.04×10 -3 ]]> <![CDATA[Cl - ]]> 97.1 <![CDATA[SO4 2- ]]> 11.6 <![CDATA[CO3 2- ]]> <![CDATA[5×10 -3 ]]> <![CDATA[HCO3 - ]]> 0.959

[0122] It can be seen from Table 5 that the components of the crude salt extract include a high concentration of Na + , Ca 2+ Mg 2+ , K + Plasma, these high-concentration salt solutions may change the osmotic pressure of embryonic blood vessels, disrupt their water and electrolyte balance, and cause strong toxic effects.

[0123] Therefore, the control group (positive control, negative control) and crude salt extract were diluted at different times (0, 2, 4, 8, 16 times), and then tested for their irritation. Figure 2 , Figure 3 , Figure 4 ;

[0124] from Figure 2-Figure 3 It can be seen that when 0.9% NaCl solution was added, the blood vessels of the chicken embryo did not change from 0s to 300s, that is, 0.9% NaCl solution was not irritating to the chicken embryo. When 0.1mol / L NaOH solution was added, the blood vessels of the chicken embryo showed symptoms of bleeding, coagulation and hemolysis in a very short time, which showed that 0.1mol / L NaOH solution showed strong irritation to the chicken embryo. Negative and positive control experiments proved the reliability of the method.

[0125] from Figure 4 It can be seen that as the dilution ratio of the crude salt extract increases, the toxic effect becomes less and less severe. After the crude salt extract and its 2-fold and 4-fold dilutions were added, the chicken embryo blood vessels showed different degrees of bleeding symptoms at 30s, 30s and 150s respectively; and when the 8-fold diluted crude salt extract was added, there was no obvious change in the chicken embryo blood vessels, which shows that the crude salt extract at this concentration is safe and non-irritating. Therefore, in the subsequent formulation, in order to meet its safety specifications, the crude salt extract diluted 8 times or more is the appropriate concentration.

[0126] Example 2

[0127] A method for preparing a mineralized skin care water containing a crude salt extract comprises the following steps:

[0128] Crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia japonica flower extract, Portulaca oleracea extract OLERACEA) extract, lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, and ethylhexylglycerin are 10%, 3%, 0.5%, 0.1%, 0.3%, 0.3%, 3%, 0.05%, 0.1%, 0.1%, 0.1%, 0.1%, 0.1%, 0.1%, 0.05%, 0.05%, 5%, 3%, 0.5%, 0.5%, 3%, 3%, and 3% by mass; make up to 100% with deionized water; mix evenly to obtain mineralized skin care water.

[0129] The obtained skin care water was subjected to performance testing, and the test results are as follows:

[0130] (1) Irritation test results:

[0131] Irritation test results Figure 5 , Figure 6 .

[0132] from Figure 5 and Figure 6 It can be seen that the mineral skin care water is clear and transparent, and the formula is mild and non-irritating. It feels refreshing and non-sticky when sprayed on the hands, absorbs quickly, has a good skin feel, and has no irritating odor.

[0133] (2) Efficacy test results:

[0134] Skin moisture test results are as follows Figure 7 .

[0135] from Figure 7It can be seen that the P values ​​at 5min, 2h, 4h and 8h are all less than 0.001, which means that the data are significantly different. Compared with the blank group (not used), the skin water content at 5min, 2h, 4h and 8h increased to varying degrees, with the left face increasing by 21.19%, 15.35%, 14.49% and 11.36% respectively, and the right face increasing by 25.56%, 18.04%, 16.59% and 14.36% respectively. At the same time, the water content results of the left and right faces also prove that this skin care water has a strong water-locking and moisturizing effect.

[0136] The test results of transepidermal water loss are as follows Figure 8 .

[0137] from Figure 8 It can be seen that at the time point of 8 hours after using the skin care water, the transepidermal water loss was significantly different from the basic data, with the left face decreasing by 11.56% and the right face decreasing by 10.78%. The immediate increase in transepidermal water loss was initially believed to be caused by a sudden and substantial increase in skin water content, because in the period from 2 hours to 8 hours, the data of both the left and right faces showed a downward trend. This shows that the skin care water has a certain effect on skin barrier repair.

[0138] Skin color test results Fig. 9 .

[0139] from Fig. 9 It can be seen that from the data of the right face, the skin color increased by 2.81%, 6.19%, 4.54% and 5.47% in 5 minutes, 2 hours, 4 hours and 8 hours respectively, which is larger than the growth rate of the left face, and there are significant differences compared with the initial data. The skin care water has a certain whitening effect, which is related to the niacinamide added in it, and is also related to the antioxidant effect of magnesium ions.

[0140] Gloss test results are as follows Fig.10 .

[0141] from Fig.10 It can be seen that the skin glossiness at each time period is significantly different from the basic data. The data of the left face is better than that of the right face, increasing by 8.71%, 14.88%, 10.53% and 11.99% at 5 minutes, 2 hours, 4 hours and 8 hours respectively. This is related to the various plant extracts added to the formula. For example, camellia extract can resist oxidation and relieve dry skin, and purslane extract can resist inflammation and soothe allergies. The small molecule collagen in the formula can also act directly on the skin, increase skin elasticity and promote metabolism.

[0142] Example 3

[0143] The crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia japonica flower extract, Portulaca oleracea extract, and the like in Example 2 were adjusted. The mass percentages of OLERACEA) extract, lactobacillus fermentation product, ectoine, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, and ethylhexylglycerin in cosmetics are 1%, 0.1%, 0.01%, 0.01%, 0.01%, 0.1%, 0.5%, 0.01%, 0.01%, 0.01%, 0.01%, 0.01%, 0.01%, 0.01%, 0.001%, 0.001%, 0.1%, 0.05%, 0.01%, 0.01%, 0.1%, 0.1%, 0.1%, and 0.1%; make up to 100% with deionized water;

[0144] The rest was the same as in Example 2 to obtain skin care water.

[0145] The obtained skin care water was subjected to performance testing, and the test results are as follows:

[0146] The skin care water has certain moisturizing properties, has a certain effect on skin barrier repair, has a certain whitening effect, and improves glossiness, but the effect is slightly worse than that of Example 2.

[0147] Example 4

[0148] The crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, Camellia sinensis leaf extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia japonica flower extract, Portulaca oleracea extract, and the like in Example 2 were adjusted. The mass percentages of OLERACEA) extract, lactobacillus fermentation product, ectoine, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, and ethylhexylglycerin in cosmetics are 12.5%, 6%, 1%, 0.5%, 0.5%, 0.5%, 5%, 0.2%, 0.2%, 0.2%, 0.2%, 0.2%, 0.2%, 0.2%, 0.1%, 0.1%, 10%, 5%, 1%, 1%, 5%, 5%, 5%; make up to 100% with deionized water;

[0149] The rest was the same as in Example 2 to obtain skin care water.

[0150] The obtained skin care water was subjected to performance testing, and the test results are as follows:

[0151] The skin care water has certain moisturizing properties, has a certain effect on skin barrier repair, has a certain whitening effect, and improves glossiness, which is not much different from the effect of Example 2.

[0152] Comparative Example 1

[0153] The crude salt extract diluent in Example 2 was omitted and replaced with water. The rest was the same as in Example 2 to obtain skin care water.

[0154] The obtained skin care water was subjected to performance testing, and the test results are as follows:

[0155] Skin water content, transepidermal water loss, skin color and gloss test results of skin care water Fig.11 .

[0156] from Fig.11 It can be seen that compared with the blank (no skin care water), except for the improvement of skin gloss in the 5-minute test, there was no obvious improvement in skin water content, transepidermal water loss and skin color.

[0157] Comparative Example 2

[0158] The crude salt extract for preparing the mineral skin care water in Example 2 was replaced with a NaCl solution with a mass concentration of 1.5%, and the other steps were the same as in Example 2 to obtain the skin care water.

[0159] The obtained skin care water was subjected to performance testing, and the test results are as follows:

[0160] Skin water content, transepidermal water loss, skin color and gloss test results of skin care water Fig.12 .

[0161] from Fig.12 It can be seen that: compared with the blank (no skin care water is used), the skin water content is significantly improved, but the transepidermal water loss and glossiness are not significantly improved, and the skin color is dark after 2 hours of testing.

[0162] Comparative Example 3

[0163] The crude salt extract for preparing the mineral skin care water in Example 2 is replaced with a mixed solution having a mass concentration of 0.0045% potassium chloride, 0.23% magnesium chloride and 1.037% calcium chloride, and the ion concentration is the same as that of the crude salt extract in Example 2; the rest is the same as in Example 2, and the skin care water is obtained.

[0164] The obtained skin care water was subjected to performance testing, and the test results are as follows:

[0165] Skin water content, transepidermal water loss, skin color and gloss test results of skin care water Fig.13 .

[0166] from Fig.13 It can be seen that: compared with the blank (no skin care water), the skin water content is significantly improved, the skin gloss is improved in the 5-minute test, but the transepidermal water loss is not improved, and the skin color is dark in the 2-hour test.

[0167] Although the present invention has been disclosed as above in the form of a preferred embodiment, it is not intended to limit the present invention. Anyone familiar with this technology can make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention should be based on the definition of the claims.

Claims

1. A cosmetic containing a crude salt extract, characterized in that: The mass percentage of the crude salt extract in the cosmetics is 0.01 to 12.5%.

2. The cosmetic according to claim 1, characterized in that: Cosmetics include mineral skin care water, essence, essence lotion, facial cream, etc.

3. The cosmetic according to claim 1, characterized in that The preparation method of crude salt extract is as follows: Dissolve the crude salt in water, filter through a membrane, and take the permeate for desalination to obtain a crude salt extract; Among them, the mass ratio of crude salt to water is 1:3-5; The pore size of the membrane in membrane filtration is 0.22 μm; Desalination is done by rotary evaporation at 40-85°C and 50-150 rpm; The ratio of the volume after desalting to the volume before desalting is 1:5-10.

4. A mineralized skin care water containing crude salt extract, characterized in that: It uses crude salt extract; wherein the mass concentration of the crude salt extract in the mineralized skin care water is 0.01-12.5%.

5. The mineralized skin care water according to claim 4, characterized in that: The ingredients of mineral skin care water include crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, tea extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia extract, Portulaca oleracea extract, Lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, parahydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, ethylhexylglycerin, and deionized water.

6. The mineralized skin care water according to claim 4, characterized in that: The mass percentage of crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, tea extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia extract, Portulaca oleracea extract, Lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, and ethylhexylglycerin in cosmetics is (1-12.5)%: (0.1-6)%: (0.01-1)%: (0.01-0.5)%: (0.01-0 .5)%:(0.1~0.5)%:(0.5~5)%:(0.01~0.2)%:(0.01~0.2)%:(0.01~0.2)%:(0.01~0.2)%:(0.01~0.2)%:(0.01~0.2)%:(0.01~0.2)%:(0.01~0.2)%:(0.001~0.1)%:(0.001~0.1)%:(0.1~10)%:(0.05~5)%:(0.01~1)%:(0.01~1)%:(0.1~5)%:(0.1~5)%:(0.1~5)%; Make up to 100% with deionized water.

7. The mineralized skin care water according to claim 4, characterized in that: The dilution factor of the crude salt extract is 8 times or more, preferably 8 to 16 times.

8. A method for preparing the mineralized skin care water containing crude salt extract according to any one of claims 4 to 7, characterized in that: The steps include: The crude salt extract, butylene glycol, collagen, sodium hyaluronate, hydrolyzed sodium hyaluronate, disodium EDTA, niacinamide, Centella asiatica extract, Polygonum cuspidatum root extract, Scutellaria baicalensis root extract, tea extract, Glycyrrhiza glabra root extract, Chamomile flower extract, Rosemary leaf extract, Camellia extract, Portulaca oleracea extract, lactobacillus fermentation product, tetrahydromethylpyrimidine carboxylic acid, allantoin, p-hydroxyacetophenone, 1,3-propylene glycol, 1,2-hexanediol, ethylhexylglycerin and deionized water are evenly mixed to obtain a mineralized skin care water.

9. An essence, characterized in that: A crude salt extract is used; the crude salt extract is diluted with water, and the mass concentration of the crude salt extract in the essence is 0.01-12.5%.

10. The essence according to claim 9, characterized in that The dilution factor of the crude salt extract is 8 times or more, preferably 8 to 16 times.

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