Traditional Chinese medicine composition for treating endometriosis and preparation method thereof

Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating endometriosis and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 60-240 parts of cudrania cochinchinensis, 30-100 parts of turtle shell, 30-120 parts of pseudo-ginseng, 30-120 parts of dragon's blood, 20-50 parts of spina gleditsiae, 20-60 parts of prepared rhizoma sparganii, 20-60 parts of prepared curcuma zedoary, 30-90 parts of concha arcae, 30-90 parts of salvia miltiorrhiza, 20-60 parts of bulbus fritillariae thunbergii, 30-90 parts of trichosanthes kirilowii maxim, 20-60 parts of Chinese red peony root, 20-60 parts of rhizoma pinellinae praeparata, 20-60 parts of angelica sinensis, 25-60 parts of peach kernel, 30-90 parts of semen cuscutae and the like. The traditional Chinese medicine composition is scientific and reasonable in compatibility, it can be known from typical cases that endometriosis can be effectively treated, the defect that endometriosis cannot be radically treated through surgical intervention in the prior art is overcome, the preparation process is simple and easy to control, and large-scale output is facilitated.

Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating endometriosis and a preparation method thereof. Background Art

[0002] Ovarian endometriosis, also known as ovarian chocolate cyst, is a cyst containing chocolate-like viscous liquid in the ovary after endometriosis spreads to the ovary. The size of the lumps varies, with large ones over 10 cm and small ones several centimeters. Affected by intrauterine estrogen, they fall off once a month, forming menstruation. If the fragments of menstruation fall off, along with menstrual blood, enter the pelvic cavity through the fallopian tubes, and implant on the surface of the ovaries or other parts of the pelvic cavity, ectopic cysts will be formed. This ectopic endometrium, under the influence of hormones, will bleed locally during each menstrual period, causing the ovaries to enlarge and form old blood cysts. This cyst can gradually increase in size, and a few may rupture during or after menstruation. It has been reported that ovarian chocolate cysts are closely related to endometrioid carcinoma and clear cell carcinoma, so they should be treated as soon as possible and cured completely.

[0003] Most existing methods involve surgical resection, hormone control, etc., which not only damage organs but also cannot completely cure the disease fundamentally.

[0004] The patent with publication number CN102872371A discloses a drug for treating endometriosis, which includes red vine, Patrinia scabra, Gleditsia sinensis, pangolin, Panax notoginseng, leech, Poria cocos, and Coix lachryma-jobi. Obviously, the raw material selection of this technical solution is single and the efficacy is limited. It is based on this that the technical solution of the present invention is proposed. Summary of the invention

[0005] In order to solve the problems existing in the prior art, the present invention provides a traditional Chinese medicine composition for treating endometriosis, which comprises the following raw materials in parts by weight: 60-240 parts of radix scutellariae, 30-100 parts of turtle shell, 30-120 parts of notoginseng, 30-120 parts of blood clotting, 20-50 parts of soapberry, 20-60 parts of processed trillium, 20-60 parts of processed zedoaria, 30-90 parts of walnut seeds, 30-90 parts of salvia miltiorrhiza, 20-60 parts of fritillaria thunbergii, 30-90 parts of trichosanthes, 20-60 parts of red peony root, 20-60 parts of processed pinellia, 20-60 parts of angelica, and 25-60 parts of peach kernel , 30-90 parts of rabbit silk seeds, 25-60 parts of Chuanxiong, 20-60 parts of cicada corpse, 20-45 parts of bupleurum, 20-60 parts of chicken's gizzard lining, 20-45 parts of processed cyperus rotundus, 20-45 parts of processed myrrh, 20-60 parts of agrimony, 20-60 parts of processed aconiti lobata, 20-60 parts of kelp, 15-60 parts of seaweed, 10-60 parts of Yuanshen, 20-40 parts of green peel, 30-60 parts of forsythia, 30-60 parts of dandelion, 80-150 parts of raw hawthorn, 25-60 parts of Morinda officinalis, 25-60 parts of raw pollen, 30-60 parts of selfheal, and 75-150 parts of raw oyster.

[0006] Preferably, the Chinese medicine composition for treating endometriosis comprises the following raw materials in parts by weight: 150 parts of radix scutellariae, 65 parts of turtle shell, 75 parts of notoginseng, 75 parts of dragon's blood, 35 parts of soapberry, 40 parts of processed trillium, 40 parts of processed zedoaria, 60 parts of walnut seeds, 60 parts of salvia miltiorrhiza, 40 parts of fritillaria thunbergii, 60 parts of trichosanthes, 40 parts of jinchi peony root, 40 parts of processed pinellia, 40 parts of angelica, 40 parts of peach kernel, 40 parts of rabbit silk 60 parts of seeds, 40 parts of Chuanxiong, 40 parts of cicada corpse, 30 parts of bupleurum, 30 parts of chicken's gizzard lining, 30 parts of processed cyperus, 30 parts of processed myrrh, 30 parts of agrimony, 30 parts of processed amaranth, 30 parts of kelp, 35 parts of seaweed, 35 parts of Yuanshen, 30 parts of green peel, 45 parts of forsythia, 45 parts of dandelion, 110 parts of raw hawthorn, 40 parts of Morinda officinalis, 40 parts of raw pollen, 45 parts of selfheal, and 110 parts of raw oyster.

[0007] For ease of understanding of the present invention, the role of raw materials of the present invention is described:

[0008] Chuanpo Stone: light taste, slightly bitter, cool in nature; has the effects of dispelling wind and dampness, promoting blood circulation and dredge menstruation; used to treat ovarian cysts, uterine fibroids, stones, hyperplasia, treatment of body congestion, nodules, gallstones, kidney stones, urinary stones, rheumatic joint pain, jaundice, stranguria, swelling, injuries, mumps, lung nodules, breast nodules, breast hyperplasia and other symptoms.

[0009] Turtle shell: salty in taste, slightly cold in nature; enters the liver and kidney meridians; has the effects of nourishing yin and suppressing yang, reducing fever and eliminating steaming, softening and dispersing nodules; used to treat symptoms such as lung cancer, cervical cancer, bone tumors, liver cancer, intestinal cancer, ovarian cancer, long-term malaria, malarial mother, breast nodules, uterine fibroids, male cavernous sclerosis, lymphadenitis, and lymph tuberculosis.

[0010] Panax notoginseng: sweet, slightly bitter, warm in nature; enters the liver, stomach, and large intestine meridians; has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, nourishing and strengthening, resisting fatigue, resistant to hypoxia, anti-aging, lowering blood lipids and blood sugar, and improving the body's immune function.

[0011] Xuejie: ​​It tastes sweet and salty, and is neutral in nature. It has the effects of dispersing blood stasis, relieving pain, stopping bleeding and promoting tissue regeneration. It is used to treat symptoms such as bruises and fractures, internal injuries and blood stasis, excessive bleeding from external injuries, scrofula, and long-term ecthyma.

[0012] Sophora flavescens: It has the effects of dispersing blood stasis and relieving pain, stopping bleeding and promoting tissue regeneration, eliminating toxins and attacking poisons, fighting cancer, and reducing swelling and promoting pus. It is used to treat symptoms such as bruises and fractures, internal injuries and blood stasis, excessive bleeding from external injuries, scrofula, and long-term ecthyma.

[0013] Prepared Tripterygium wilfordii: sweet and bitter in taste, neutral in nature; enters the lung meridian and heart meridian; has the effects of promoting blood circulation and stopping bleeding, breaking blood and promoting qi, eliminating accumulation and relieving pain;. It is commonly used in the clinic to treat lumps, dysmenorrhea, amenorrhea due to blood stasis, chest pain, heart pain, and food accumulation and distension. Modern experimental studies have shown that Tripterygium wilfordii extract has multiple pharmacological activities such as anti-tumor, anti-thrombotic, platelet aggregation inhibition and analgesia.

[0014] Prepared Curcuma: tastes pungent and bitter, and is warm in nature; it enters the liver and spleen meridians; it has the effects of promoting qi and removing blood, eliminating accumulation and relieving pain; it is used to treat symptoms such as abdominal masses, amenorrhea due to blood stasis, chest pain, heart pain, and bloating and pain due to food accumulation.

[0015] Corrugated seeds: sweet and salty in taste, neutral in nature; enter the liver, lung and stomach meridians; have the effects of eliminating phlegm and removing blood stasis, softening and dispersing lumps, reducing acid and relieving pain; used to treat scrofula, goiter, lumps due to symptoms, stubborn phlegm and long-term cough, stomachache and acid reflux, tooth decay, traumatic bleeding, frostbite and burns.

[0016] Salvia miltiorrhiza: bitter in taste, slightly cold in nature; has the effects of breaking up tumors and lumps, relieving restlessness, invigorating qi, nourishing blood, and curing chronic diseases of the heart and abdomen; used to treat symptoms such as evil qi in the heart and abdomen, accumulation of cold and heat, and numbness of the feet.

[0017] Fritillaria thunbergii: bitter in taste, cold in nature; enters the lung and heart meridians; has the effects of clearing away heat, resolving phlegm and relieving cough, detoxifying, dispersing knots and eliminating carbuncle. It is mainly used to treat cough, scrofula, goiter, sore, lung carbuncle, breast carbuncle and other symptoms.

[0018] Trichosanthes: sweet in taste, cold in nature; enters the lung, stomach, and large intestine meridians; has the effects of clearing away heat and phlegm, relieving chest tightness and dispersing stagnation, moistening dryness and lubricating the intestines.

[0019] Jin Chishao: bitter in taste, slightly cold in nature; enters the Liver Channel; has the effects of clearing heat and cooling blood, dispersing blood stasis and relieving pain; used to treat symptoms such as amenorrhea due to blood stasis, dysmenorrhea, and high fever.

[0020] Processed Pinellia: spicy in taste, warm in nature; enters the spleen, stomach, and lung meridians; used to treat symptoms such as cough and asthma due to excessive phlegm, dizziness due to phlegm and fluid, dizziness due to wind and phlegm, and syncope due to phlegm.

[0021] Angelica: sweet in taste; has the effects of nourishing blood, activating blood circulation, regulating menstruation and relieving pain, moistening dryness and lubricating the intestines; used to treat symptoms of blood deficiency, irregular menstruation, amenorrhea, dysmenorrhea, accumulation of masses, metrorrhagia, abdominal pain due to deficiency and cold, paralysis, numbness of the skin, dry intestines and difficulty in defecation, heaviness after dysentery, carbuncles, ulcers, and injuries from falls.

[0022] Peach kernel: bitter and sweet in taste, neutral in nature; enters the heart, liver, and large intestine meridians; used to treat dysmenorrhea, postpartum lochia, lower abdominal pain, old injuries, blood stasis and other symptoms.

[0023] Rabbit silk seed: spicy and sweet, neutral in nature; enters the liver, kidney and spleen meridians; has the effects of nourishing the kidney and essence, nourishing the liver and improving eyesight, consolidating the fetus and stopping diarrhea; used to treat symptoms such as low back and knee pain, spermatorrhea, impotence, premature ejaculation, infertility, thirst, stranguria, enuresis, blurred vision and tinnitus, fetal movement disorder, miscarriage, diarrhea, etc.

[0024] Chuanxiong: spicy in taste, warm in nature; enters the liver, gallbladder, and pericardium meridians; has the effects of promoting blood circulation and qi, dispelling wind and relieving pain; used to treat symptoms such as chest pain, heart pain, stabbing pain in the chest and ribs, swelling and pain from falls, irregular menstruation, amenorrhea, dysmenorrhea, abdominal pain due to lumps, headache, and rheumatic pain.

[0025] Dead cicada: salty and spicy in taste, neutral in nature; enters the liver, lung and stomach meridians; has the effects of calming wind and stopping convulsions, dispelling wind and relieving pain, resolving phlegm and dispersing nodules; used to treat symptoms such as liver wind with phlegm, epilepsy and convulsions, breast nodules, lung nodules, and thyroid nodules.

[0026] Bupleurum: It tastes pungent and bitter, and is slightly cold in nature; it enters the liver, gallbladder, and lung meridians; it has the effects of harmonizing and reducing fever, soothing the liver and relieving depression, and raising Yang Qi; for symptoms such as irregular menstruation, dysmenorrhea, and scanty menstruation, Bupleurum can effectively regulate the menstrual cycle and relieve symptoms such as dysmenorrhea.

[0027] Chicken's gizzard lining: Chicken's gizzard lining has a softening effect on hard lumps in the human body. It is used to treat symptoms such as accumulation of masses, myoma cysts, uterine fibroids, and adenomyosis. From a Chinese medicine perspective, it is related to blood stasis and is mainly used to promote blood circulation.

[0028] Processed Cyperus rotundus: tastes spicy, slightly bitter, slightly sweet, and is neutral in nature; it enters the liver, spleen, and triple burner meridians; it has the effects of soothing the liver and relieving depression, regulating menstruation and relieving pain.

[0029] Prepared myrrh: pungent and bitter in taste, neutral in nature; enters the heart, liver and spleen meridians; has the effects of dispersing blood stasis, relieving pain, reducing swelling and promoting tissue regeneration; used to treat chest pain, heart pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, rheumatic pain, traumatic injuries, carbuncles, ulcers and other symptoms.

[0030] Herba Agrimoniae: bitter and astringent in taste, neutral in nature; enters the lung, liver, and spleen meridians; has the effects of astringency, hemostasis, dysentery, and insecticide; used to treat hemoptysis, hematemesis, hematuria, bloody stool, dysentery, metrorrhagia, leukorrhea, fatigue, carbuncle, bruises, and traumatic bleeding.

[0031] Processed Ophiopogon japonicus: bitter, astringent, and neutral in nature; enters the lung, liver, and spleen meridians; has the effects of astringing, stopping bleeding, and stopping dysentery.

[0032] Kelp: It has the effects of eliminating phlegm, softening and dispersing nodules, promoting diuresis and reducing swelling; it is used to treat symptoms such as goiter, cervical lymphadenopathy, bronchitis, tuberculosis, cough and senile cataracts, and is also suitable for the treatment of malignant lymphosarcoma, thyroid cancer, esophageal cancer, breast cancer, etc.

[0033] Seaweed: It has antiviral, anti-cancer, anti-cancer, leukemia prevention, blood pressure lowering, blood lipid lowering, and heart protection effects.

[0034] Yuanshen: tastes bitter and salty, and is cold in nature; it enters the liver, stomach, and kidney meridians; it has the effects of eliminating phlegm, softening and dispersing nodules, promoting diuresis and reducing swelling, nourishing yin and promoting body fluid, and purging fire and detoxifying.

[0035] Qingpi: bitter and spicy in taste, warm in nature; enters the liver, gallbladder and stomach meridians; has the effects of soothing the liver and breaking up qi, eliminating accumulation and stagnation; used to treat symptoms such as chest and flank distension and pain, hernia pain, breast lumps, breast abscesses, food accumulation and qi stagnation, and abdominal distension and pain.

[0036] Forsythia: It has the effects of clearing away heat and detoxifying, reducing swelling and dispersing nodules, and evacuating wind-heat; Forsythia also has multiple pharmacological effects such as anti-pathogenic microorganisms, antipyretic, anti-inflammatory, antioxidant, antiemetic, liver protection, and anti-tumor.

[0037] Dandelion: bitter, sweet, and cold in nature; enters the liver and stomach meridians; has the effects of clearing away heat and detoxifying, reducing swelling and dispersing nodules, and promoting diuresis and relieving stranguria; used to treat symptoms such as uterine fibroids, ovarian cysts, and pelvic inflammatory disease.

[0038] Raw hawthorn: used to treat dysmenorrhea, blood stasis and other symptoms; has the effects of preventing arteriosclerosis and cancer.

[0039] Morinda officinalis: sweet, pungent, slightly warm in nature; enters the kidney and liver meridians; has the effects of tonifying the kidney, strengthening yang, benefiting essence, and benefiting blood. Traditional Chinese medicine believes that the liver governs tendons and the kidney governs bones. Morinda officinalis enters the liver and kidney meridians, and is sweet, warm and tonifying, so it also has the effect of strengthening tendons and bones, and is suitable for symptoms such as kidney deficiency and soft bones, and weak tendons and bones. Morinda officinalis is pungent, warm and dispersing, and has the effects of dispelling cold and dampness, and expelling cold. It has an improvement effect on symptoms such as rheumatic arthralgia, cold waist and knees, cold uterus, and irregular menstruation.

[0040] Raw Puhuang: sweet, spicy, neutral in nature; enters the liver, heart, and spleen meridians; has the effects of stopping bleeding, dispersing blood stasis, and promoting diuresis and relieving stranguria. Raw Puhuang can be used to lower blood lipids, resist atherosclerosis, and treat amenorrhea, dysmenorrhea, abdominal pain, swelling and pain caused by falls, and bloody pain.

[0041] Prunella Vulgaris: bitter, pungent, and cold in nature; enters the liver and gallbladder meridians; has the effects of clearing liver fire and relieving depression; used to treat scrofula, goiter, mastitis, red and painful eyes, liver wind headache and dizziness, liver fire inflammation, and various diseases caused by hyperactivity of liver yang, and also has anti-cancer effects.

[0042] Raw oysters: have the effects of calming the liver and suppressing yang, softening and dispersing nodules, and astringing and consolidating; they are mainly used to treat dizziness and tinnitus, tremors in the hands and feet, palpitations and insomnia, irritability, epilepsy, scrofula and goiter, breast lumps, spontaneous sweating and night sweats, spermatorrhea and frequent urination, metrorrhagia and leukorrhea, acid regurgitation, stomach pain, eczema and sores, etc.

[0043] Main medicine: Chuanpo Stone, Biejia, Panax notoginseng, Xuejie;

[0044] Assistant drugs: Gleditsia sinensis, processed Tripterygium wilfordii, processed Curcuma zedoaria, Fructus walnutii, Salvia miltiorrhiza, Fructus trichosanthis, Fritillaria thunbergii, Radix Paeoniae chinensis;

[0045] Auxiliary drugs: processed Pinellia, Chinese Angelica, Peach Kernel, Cuscuta, Ligusticum chuanxiong, Bombyx batryticatus, Bupleurum, Chicken Gizzard Stone, processed Cyperus rotundus, processed Myrrh, Agrimonia, processed Fructus aconiti Lateralis;

[0046] Auxiliary drugs: kelp, seaweed, Yuanshen, green peel, forsythia, dandelion, raw hawthorn, Morinda officinalis, raw pollen, selfheal, raw oyster.

[0047] Based on the same technical concept, the present invention further provides a method for preparing a Chinese medicine composition for treating endometriosis, the preparation method comprising the following steps:

[0048] (1) mixing all raw materials, drying, sterilizing and crushing in sequence to obtain Chinese medicine powder;

[0049] (2) mixing and stirring the Chinese medicine powder and the adhesive to increase viscosity to obtain a mixture;

[0050] (3) extruding the mixture into strips and cutting into particles;

[0051] (4) Polishing and drying the particles to obtain the Chinese medicine composition for treating endometriosis.

[0052] Preferably, in step (1), the drying is air-blast drying, the drying temperature is 40 to 60° C., and the drying time is 40 to 60 min.

[0053] Preferably, in step (1), the powder is crushed to pass through a 120-mesh sieve.

[0054] Preferably, in step (2), the adhesive is starch slurry; the concentration of the starch slurry is 15-20wt%.

[0055] Preferably, in step (2), the mass ratio of the traditional Chinese medicine powder to the adhesive is 2.5 to 3:1.

[0056] Preferably, in step (4), the drying temperature is 30-40° C. and the drying time is 6-8 hours.

[0057] It should be noted that seafood should not be eaten when taking the Chinese medicine composition of the present invention, and seafood allergy patients should use it with caution or prohibit it. In addition, one bottle of the Chinese medicine composition of the present invention is 96 grams, three times a day, 16 grams each time, one bottle every two days; a course of treatment is 20 days in total.

[0058] The beneficial effects of the present invention are:

[0059] The Chinese medicine composition of the present invention has a scientific and reasonable compatibility. It can be known from typical cases that it can effectively treat endometriosis, solving the drawback of the prior art that surgical intervention cannot cure it radically. In addition, the preparation process is simple and easy to control, which is conducive to large-scale production. DETAILED DESCRIPTION

[0060] To make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be described in detail below. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other implementation methods obtained by ordinary technicians in this field without creative work belong to the scope of protection of the present invention.

[0061] Example 1

[0062] This embodiment provides a method for preparing a Chinese medicine composition for treating endometriosis, the preparation method comprising the following steps:

[0063] (1) All raw materials are mixed, first dried at 40° C. for 60 min, sterilized, and ground to pass through a 120-mesh sieve to obtain Chinese medicine powder;

[0064] (2) mixing the Chinese medicinal powder and starch slurry (concentration 15 wt%) at a mass ratio of 2.5:1 to increase viscosity and obtain a mixture;

[0065] (3) extruding the mixture into strips and cutting into particles;

[0066] (4) Polishing the particles and drying them at 30° C. for 8 h to obtain the traditional Chinese medicine composition for treating endometriosis.

[0067] In the present embodiment, the specific amount of raw materials is: 60g of Chuanpo Stone, 30g of Biejia, 30g of Panax notoginseng, 30g of Sanguisorba officinalis, 20g of Sophora flavescens, 20g of processed Tripterygium wilfordii, 30g of processed Curcuma zedoaria, 30g of Corrugated Zi, 30g of Salvia miltiorrhiza, 20g of Fritillaria thunbergii, 30g of Trichosanthes, 20g of Jin Chishao, 20g of processed Pinellia ternata, 20g of Angelica sinensis, 25g of Peach Kernel, 30g of Rabbit Silk Seed, 25g of Chuanxiong, 20g of Cicada, 20g of Bupleurum, 20g of Chicken Gizzard, 20g of processed Cyperus rotundus, 20g of processed Myrrh, 20g of Agrimoniae, 20g of processed Wulingzhi, 20g of Kelp, 15g of Sargassum, 10g of Yuanshen, 20g of Qingpi, 30g of Forsythia suspensa, 30g of Taraxacum, 80g of Raw Hawthorn, 25g of Morinda officinalis, 25g of Raw Typhae Pollen, 30g of Prunella Vulgaris, and 75g of Raw Oyster.

[0068] Example 2

[0069] This embodiment provides a method for preparing a Chinese medicine composition for treating endometriosis, the preparation method comprising the following steps:

[0070] (1) All raw materials are mixed, first dried at 60° C. for 40 min, sterilized, and ground to pass through a 120-mesh sieve to obtain Chinese medicine powder;

[0071] (2) mixing the Chinese medicinal powder and starch slurry (concentration 20 wt%) at a mass ratio of 3:1 to increase viscosity and obtain a mixture;

[0072] (3) extruding the mixture into strips and cutting into particles;

[0073] (4) Polishing the particles and drying them at 40° C. for 6 hours to obtain the traditional Chinese medicine composition for treating endometriosis.

[0074] In this embodiment, the specific amounts of raw materials are: 240g of Chuanpo Stone, 100g of Biejia, 120g of Panax Notoginseng, 120g of Sanguisorba Officinalis, 50g of Sophora japonica, 60g of processed Tripterygium wilfordii, 60g of processed Curcuma zedoaria, 90g of Corrugated Seed, 90g of Salvia miltiorrhiza, 60g of Fritillaria thunbergii, 90g of Trichosanthes kirilowii, 60g of Radix Paeoniae Rubra, 60g of processed Pinellia ternata, 60g of Angelica sinensis, 60g of Peach Kernel, 90g of Rabbit Silk Seed, 60g of Chuanxiong. 0g, 60g dead cicada, 45g bupleurum, 60g chicken gizzard lining, 45g processed cyperus rotundus, 45g processed myrrh, 60g herb agrimony, 60g processed aconite, 60g kelp, 60g seaweed, 60g Yuanshen, 40g green peel, 60g forsythia, 60g dandelion, 150g raw hawthorn, 60g Morinda officinalis, 60g raw pollen, 60g selfheal, 150g raw oyster.

[0075] Example 3

[0076] This embodiment provides a method for preparing a Chinese medicine composition for treating endometriosis, the preparation method comprising the following steps:

[0077] (1) All raw materials are mixed, first dried at 50° C. for 50 min, sterilized, and ground to pass through a 120-mesh sieve to obtain Chinese medicine powder;

[0078] (2) mixing the Chinese medicinal powder and starch slurry (concentration 18 wt%) at a mass ratio of 3:1 to increase viscosity and obtain a mixture;

[0079] (3) extruding the mixture into strips and cutting into particles;

[0080] (4) Polishing the particles and drying them at 35° C. for 7 hours to obtain the traditional Chinese medicine composition for treating endometriosis.

[0081] In this embodiment, the specific amounts of raw materials are: 150g of radix scutellariae, 65g of turtle shell, 75g of notoginseng, 75g of blood clotting, 35g of soapberry, 40g of processed three-edged lanceolate, 40g of processed zedoaria, 60g of corrugated seeds, 60g of salvia miltiorrhiza, 40g of fritillaria thunbergii, 60g of trichosanthes, 40g of red peony root, 40g of processed pinellia, 40g of angelica, 40g of peach kernel, 60g of rabbit silk seed, 40g of chuanxiong g, 40g of dead cicada, 30g of bupleurum, 30g of chicken gizzard lining, 30g of processed cyperus rotundus, 30g of processed myrrh, 30g of cranesbill, 30g of processed aconite, 30g of kelp, 35g of seaweed, 35g of Yuanshen, 30g of green tangerine peel, 45g of forsythia, 45g of dandelion, 110g of raw hawthorn, 40g of Morinda officinalis, 40g of raw pollen, 45g of selfheal, 110g of raw oyster.

[0082] Verification Example

[0083] Case 1: Li Moumou, consultation date December 2004, severe dysmenorrhea, pain during each menstrual period and one week before and after, main symptoms: severe anal pain, unable to squat and unbearable pain, poor effect of taking painkillers. Examination: uterus 99×81mm, bilateral ovarian chocolate cysts, right ovary 90×70mm, left ovary 80×60mm, pelvic adhesions, taking the Chinese medicine composition obtained in Example 3 for 8 courses of treatment to recover.

[0084] Case 2: Li Moumou, the time of consultation was March 2017. She had been infertile for many years after marriage and had an ectopic pregnancy after IVF in the hospital. After the operation, she underwent fallopian tube anastomosis. After the operation, she was amenorrhea for half a year. The hospital examination showed bilateral ovarian polycystic ovary syndrome. After one year of conditioning, she still had amenorrhea. Examination during the consultation: the uterus was 60×55mm, normal in size, with partial adhesions in the uterine cavity, liquid dark areas, multiple polyps, and both ovaries were polycystic ovaries, the right ovary was 88×80mm, and the left ovary was 90×78mm. After taking the Chinese medicine composition obtained in Example 3 for 11 months, she returned to normal. After stopping the drug for 2 months, she successfully had an intrauterine pregnancy and subsequently gave birth to a baby girl.

[0085] Case 3: Chen Moumou, consultation time February 2018, dysmenorrhea, scanty menstruation, coffee-colored, cycle 36-40 days, multiple treatments did not improve. After consultation, examination: multiple fibroids in the wall of uterine fibroids, about 20 of 4×3mm, chocolate cysts on the right ovary combined with polycystic ovaries, uterus 61×50mm, wall full of 4.1×3.3mm, about 20 fibroids. Right ovary 46×29mm. Polycystic ovaries combined with chocolate cysts have old ones above, including about sixty-five 5×5mm small cysts adhered to the lower segment of the uterus, and about 66 5×10mm cysts in the left ovary 50×35mm, and a small amount of pelvic effusion. Diagnosis: multiple small uterine fibroids. Bilateral ovarian chocolate cysts combined with polycystic ovaries, endometriosis shifted to the pelvic cavity causing pelvic adhesions. Completely cured after taking the Chinese medicine composition obtained in Example 3 for 9 courses of treatment.

[0086] Case 4: Shen Moumou, after combined uterine and abdominal surgery with fallopian tube guidewire and chocolate cyst removal, had amenorrhea for 9 months and scanty menstruation. Examination of the uterus showed that it was 80×70mm, covered with intramural fibroids, 70×60mm chocolate cyst on the right ovary, 60×50mm chocolate cyst on the left ovary, 50×40mm old pelvic cyst, and endometriosis. After taking the Chinese medicine composition obtained in Example 3 for 6 courses of treatment, she recovered and gave birth to a baby boy.

[0087] Case 5: Chen, 26 years old, suffered from dysmenorrhea and infertility after marriage. She was examined at a higher-level hospital for adenomyosis, bilateral ovarian chocolate, and pelvic adhesions and fallopian tube obstruction. She underwent bilateral ovarian chocolate cyst dissection and bilateral fallopian tube separation in the hospital. Two years after the operation, she still had dysmenorrhea and infertility. Examination: The uterus was large, 76×60mm, adenomyosis, the right ovarian chocolate cyst was 68×66mm, the left ovarian chocolate cyst was 80×60mm, and the fallopian tube was obstructed by pelvic adhesions. She took the Chinese medicine composition obtained in Example 3 for 7 courses of treatment and recovered. She gave birth to a boy later.

[0088] Case 6: Chang Moumou, infertile for 1 year after marriage, received medical examination: bilateral ovarian chocolate cysts, uterus 65×66mm, adenomyosis, bilateral ovarian chocolate, right ovary 80×75mm, left ovary 70×65mm. After taking the Chinese medicine composition obtained in Example 3 for 7 courses of treatment, she was cured and subsequently gave birth to a boy and a girl.

[0089] Case 7: Zhang Moumou, multiple intramural uterine myomas, bilateral ovarian chocolate cysts, severe dysmenorrhea, and drug treatment. After the consultation, the examination showed that the uterus was 150×130mm in size, and there were intramural myomas of varying sizes, 78×60mm, 56×50mm, 40×33mm, 30×25mm, etc., and adenomyosis was also present. Both ovarian chocolates were ovarian chocolate cysts, with the right ovary being 85×80mm and the left being 65×60mm. Taking the Chinese medicine composition obtained in Example 3 for 2 courses of treatment for dysmenorrhea has been cured, and 11 courses of treatment for uterine fibroids and ovarian chocolate cysts have been completely cured. Three months after stopping the medication, she became pregnant, and subsequently gave birth to twins, and two years later, she gave birth to twins.

[0090] Case 8: Li Moumou, had two menstrual periods and dysmenorrhea one year after the birth of the first child. Then she had amenorrhea, and she still had amenorrhea after long-term treatment with Chinese and Western medicine. Medical examination: uterus 71×64mm, adenomyosis, small myoma. The left ovary had a 58×46mm chocolate cyst combined with polycystic ovary, and the right ovary was 65×60mm, with a 29.70×25.57mm mixed mass (suspected teratoma). Take the Chinese medicine composition obtained in Example 3 for 4 courses of treatment. After recovery from treatment, she successfully conceived a second child in September 2022.

[0091] Case 9: Zhang XX. 40 years old, consultation time October 2023, dysmenorrhea. Examination of the uterus, 67×60mm, thick endometrium with strong echo, adenomyosis, and uterine effusion. There are small myomas, the largest 8×7mm, and the right ovary is 63×40mm. Chocolate cyst combined with polycystic ovary and adhesion to the posterior wall of the uterus. Left ovary, 58×60mm, chocolate cyst combined with polycystic ovary and adhesion to the posterior wall of the uterus, with strong echoes of 14×10mm, a cyst of 61×54mm, and old rupture marks of the cyst of 21×12mm. After 7 months of treatment, she became pregnant smoothly, and all indicators were normal.

[0092] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A Chinese medicine composition for treating endometriosis, characterized in that: The invention comprises the following raw materials in parts by weight: 60-240 parts of radix scutellariae, 30-100 parts of turtle shell, 30-120 parts of notoginseng, 30-120 parts of blood clotting, 20-50 parts of soapberry, 20-60 parts of processed trillium, 20-60 parts of processed zedoaria, 30-90 parts of walnut seeds, 30-90 parts of salvia miltiorrhiza, 20-60 parts of fritillaria thunbergii, 30-90 parts of trichosanthes, 20-60 parts of red peony root, 20-60 parts of processed pinellia, 20-60 parts of angelica, 25-60 parts of peach kernel, 30-90 parts of rabbit silk seed, 25-60 parts of ligusticum chuanxiong, 20-60 parts of cicada corpse, 20-45 parts of bupleurum, 20-60 parts of chicken's gizzard lining, 20-45 parts of processed cyperus rotundus, 20-45 parts of processed myrrh, 20-60 parts of herba agrimonii, 20-60 parts of processed aconiti lobata, 20-60 parts of kelp, 15-60 parts of seaweed, 10-60 parts of Radix Yuanshen, 20-40 parts of green peel, 30-60 parts of forsythia, 30-60 parts of dandelion, 80-150 parts of raw hawthorn, 25-60 parts of Morinda officinalis, 25-60 parts of raw pollen, 30-60 parts of selfheal, and 75-150 parts of raw oyster.

2. The Chinese medicine composition for treating endometriosis according to claim 1, characterized in that: The invention comprises the following raw materials in parts by weight: 150 parts of radix scutellariae, 65 parts of turtle shell, 75 parts of notoginseng, 75 parts of dragon's blood, 35 parts of soapberry, 40 parts of processed trillium, 40 parts of processed zedoaria, 60 parts of walnut seeds, 60 parts of salvia miltiorrhiza, 40 parts of fritillaria thunbergii, 60 parts of trichosanthes, 40 parts of jin red peony root, 40 parts of processed pinellia, 40 parts of angelica, 40 parts of peach kernel, 60 parts of rabbit silk seed, 40 parts of chuanxiong, 40 parts of dead cicada, 30 parts of bupleurum, 30 parts of chicken's gizzard lining, 30 parts of processed cyperus, 30 parts of processed myrrh, 30 parts of herba agrimonii, 30 parts of processed aconiti lobata, 30 parts of kelp, 35 parts of seaweed, 35 parts of Radix Yuanshen, 30 parts of green peel, 45 parts of Fructus Forsythiae, 45 parts of Herba Taraxaci, 110 parts of raw hawthorn, 40 parts of Morinda officinalis, 40 parts of raw pollen, 45 parts of Herba Prunellae, and 110 parts of raw oyster.

3. The method for preparing the Chinese medicine composition for treating endometriosis according to claim 1 or 2, characterized in that: The preparation method comprises the following steps: (1) mixing all raw materials, drying, sterilizing and crushing in sequence to obtain Chinese medicine powder; (2) mixing and stirring the Chinese medicine powder and the adhesive to increase viscosity to obtain a mixture; (3) extruding the mixture into strips and cutting into particles; (4) Polishing and drying the particles to obtain the Chinese medicine composition for treating endometriosis.

4. The preparation method according to claim 3, characterized in that: In step (1), the drying is air-blast drying, the drying temperature is 40 to 60° C., and the drying time is 40 to 60 min.

5. The preparation method according to claim 3, characterized in that: In step (1), the powder is crushed to pass through a 120-mesh sieve.

6. The preparation method according to claim 3, characterized in that: In step (2), the adhesive is starch slurry; the concentration of the starch slurry is 15-20wt%.

7. The preparation method according to claim 3, characterized in that: In step (2), the mass ratio of the traditional Chinese medicine powder to the adhesive is 2.5 to 3:

1.

8. The preparation method according to claim 3, characterized in that: In step (4), the drying temperature is 30-40° C. and the drying time is 6-8 hours.