External hemostatic and preparation method thereof

The topical hemostatic drugs prepared by combining the aromatherapy, sausage, and celestial grass have solved the problems of complex ingredients, complicated preparation and poor hemostatic effect, achieving rapid and effective hemostatic effect, and ensuring safety Reliable use.

CN119405725APending Publication Date: 2025-02-11涂碧华
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Patent Information

Application Number
CN202411638199.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-16
Publication Date
2025-02-11

AI Technical Summary

Technical Problem

The existing formulas for topical hemostasis Chinese medicines have complex ingredients, cumbersome preparation technology, and uneven hemostasis effects, making it difficult to meet the needs of rapid and effective hemostasis.

Method used

The effective combination of fragrance-lowering, drought lotus grass and crane grass is prepared into an external hemostatic drug through crushing, sieving, mixing, sterilization and other processes, which can quickly absorb the blood of the wound and form a gel-like substance to block the wound.

Benefits of technology

It achieves a fast and effective hemostasis effect, and since the raw materials are natural plant extracts, they have no toxic side effects, and are safe and reliable in use.

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Abstract

The invention discloses an external hemostatic and a preparation method thereof. The external hemostatic comprises the following components in parts by weight: 10-20 parts of lignum dalbergiae odoriferae, 5-10 parts of herba ecliptae and 5-10 parts of herba agrimoniae. The preparation method of the external hemostatic comprises the following steps: 1) raw material preparation: respectively preparing the dalbergia wood, the eclipta alba and the hairyvein agrimony in parts by weight; 2) crushing treatment: respectively crushing the lignum dalbergiae odoriferae, the herba ecliptae and the herba agrimoniae by using a crusher, and respectively sieving the crushed raw materials with a sieve of 80-100 meshes to obtain lignum dalbergiae odoriferae fine powder, herba ecliptae fine powder and herba agrimoniae fine powder; (3) uniformly mixing: stirring and mixing the obtained lignum dalbergiae odoriferae fine powder, herba ecliptae fine powder and herba agrimoniae fine powder, and sufficiently and uniformly mixing all the components; step 4) sterilization treatment: sterilizing the uniformly mixed medicinal powder; (5) bottling and sealing: putting the sterilized medicinal powder into a clean bottle, sealing, and storing in a dark place.
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Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, in particular to an external hemostatic drug and a preparation method thereof. Background Art

[0002] Traumatic bleeding is a common emergency in daily life. Timely and effective hemostasis is of great significance for reducing blood loss, protecting wounds and promoting healing. Traditional Chinese medicine is widely used in the field of hemostasis because of its natural characteristics and few side effects.

[0003] However, the existing external hemostatic Chinese medicine formulas are often complex in composition, cumbersome in preparation process, and have varying hemostatic effects. Therefore, it is of great significance to develop an external hemostatic medicine with simple composition, convenient preparation, and significant hemostatic effect. Summary of the invention

[0004] The technical problem to be solved by the present invention is to overcome the defects of the above-mentioned technology and provide an external hemostatic drug and a preparation method thereof.

[0005] In order to solve the above technical problems, the technical solution provided by the present invention is an external hemostatic drug, comprising the following components by weight: 10-20 parts of Dalbergia odorifera, 5-10 parts of Eclipta prostrata, and 5-10 parts of Agrimoniae.

[0006] Furthermore, the invention comprises the following components in parts by weight: 10 parts of Dalbergia odorifera, 5 parts of Eclipta prostrata and 5 parts of Agrimoniae.

[0007] Furthermore, the invention comprises the following components in parts by weight: 16 parts of Dalbergia odorifera, 8 parts of Eclipta prostrata and 8 parts of Agrimoniae.

[0008] Furthermore, the invention comprises the following components in parts by weight: 20 parts of Dalbergia odorifera, 10 parts of Eclipta prostrata and 10 parts of Agrimoniae.

[0009] Furthermore, the present invention also provides a method for preparing the external hemostatic drug, comprising the following steps:

[0010] Step 1) Raw material preparation: prepare Dalbergia odorifera, Eclipta prostrata, and Agrimonia scabra respectively according to weight parts;

[0011] Step 2) pulverizing: using a pulverizer to pulverize the dalbergia odorifera, eclipta prostrata, and agrimony, and sieving the pulverized raw materials respectively, the sieve having a mesh size of 80-100, to obtain dalbergia odorifera fine powder, eclipta prostrata fine powder, and agrimony fine powder;

[0012] Step 3) uniformly mixing: stirring and mixing the obtained Dalbergia odorifera powder, Eclipta prostrata powder and Agrimoniae scabra powder to make the components fully and uniformly mixed;

[0013] Step 4) Sterilization: sterilize the mixed powder;

[0014] Step 5) Bottling and sealing: Put the sterilized powder into a clean bottle, seal it and store it away from light.

[0015] Furthermore, the sterilization treatment method in step 4 is to use high temperature and high pressure steam sterilization, wherein the temperature of the steam is controlled at 121-134° C. and the time is 15-30 minutes.

[0016] The sources of raw materials used in the present invention are as follows:

[0017] Dalbergia odorifera: pungent, warm; enters the liver and spleen meridians; removes blood stasis and stops bleeding, regulates qi and relieves pain; used for hematemesis, epistaxis, bleeding from trauma, flank pain due to liver depression, stabbing pain in the chest, pain from falls, vomiting and abdominal pain.

[0018] Eclipta prostrata: enters the liver meridian and kidney meridian; cools blood, stops bleeding, tonifies the kidney, and replenishes yin; treats vomiting blood, coughing up blood, epistaxis, hematuria, bloody stool, bloody dysentery, and bleeding from knife wounds.

[0019] Herba Agrimoniae: bitter, astringent, neutral; enters the heart and liver meridians; astringent and hemostatic, antimalarial, antidysentery, detoxifying, and tonifying; used for hemoptysis, hematemesis, metrorrhagia, malaria, bloody dysentery, carbuncles, sores, vaginal itching, leucorrhea, exhaustion and strain.

[0020] Compared with the prior art, the advantages of the present invention are as follows: the external hemostatic drug provided by the present invention has a reasonable formula design, and the external hemostatic drug prepared by effectively combining Dalbergia odorifera, Eclipta prostrata and Agrimonia scabra can quickly absorb blood from a wound to form a gel-like substance, thereby effectively plugging the wound and achieving the purpose of rapid hemostasis, and has a good hemostatic effect; at the same time, the raw materials used are all natural plant extracts, have no toxic side effects, and are safe and reliable to use. DETAILED DESCRIPTION

[0021] The following is a further detailed description of an external hemostatic drug and a preparation method thereof according to the present invention in conjunction with embodiments.

[0022] Example 1

[0023] An external hemostatic medicine comprises the following components by weight: 10 parts of Dalbergia odorifera, 5 parts of Eclipta prostrata, and 5 parts of Agrimoniae;

[0024] The preparation method of the external hemostatic drug comprises the following steps:

[0025] Step 1) Raw material preparation: prepare Dalbergia odorifera, Eclipta prostrata, and Agrimonia scabra respectively according to weight parts;

[0026] Step 2) pulverizing: using a pulverizer to pulverize the dalbergia odorifera, eclipta herb, and agrimony, and sieving the pulverized raw materials respectively, the sieve is 80 mesh, and the dalbergia odorifera fine powder, eclipta herb fine powder, and agrimony fine powder can be obtained;

[0027] Step 3) uniformly mixing: stirring and mixing the obtained Dalbergia odorifera powder, Eclipta prostrata powder and Agrimoniae scabra powder to make the components fully and uniformly mixed;

[0028] Step 4) Sterilization: sterilize the mixed powder;

[0029] The sterilization treatment method is to use high temperature and high pressure steam sterilization, wherein the steam temperature is controlled at 121°C and the time is 15 minutes;

[0030] Step 5) Bottling and sealing: Put the sterilized powder into a clean bottle, seal it and store it away from light.

[0031] Example 2

[0032] An external hemostatic medicine comprises the following components by weight: 16 parts of Dalbergia odorifera, 8 parts of Eclipta prostrata, and 8 parts of Agrimoniae;

[0033] The preparation method of the external hemostatic drug comprises the following steps:

[0034] Step 1) Raw material preparation: prepare Dalbergia odorifera, Eclipta prostrata, and Agrimonia scabra respectively according to weight parts;

[0035] Step 2) pulverizing: using a pulverizer to pulverize the dalbergia odorifera, eclipta prostrata, and agrimony, and sieving the pulverized raw materials respectively, the sieve having a 90-mesh screen to obtain dalbergia odorifera fine powder, eclipta prostrata fine powder, and agrimony fine powder;

[0036] Step 3) uniformly mixing: stirring and mixing the obtained Dalbergia odorifera powder, Eclipta prostrata powder and Agrimoniae scabra powder to make the components fully and uniformly mixed;

[0037] Step 4) Sterilization: sterilize the mixed powder;

[0038] The sterilization treatment method is to use high temperature and high pressure steam sterilization, wherein the temperature of the steam is controlled at 126°C and the time is 22 minutes;

[0039] Step 5) Bottling and sealing: Put the sterilized powder into a clean bottle, seal it and store it away from light.

[0040] Example 3

[0041] An external hemostatic medicine comprises the following components by weight: 20 parts of Dalbergia odorifera, 10 parts of Eclipta prostrata, and 10 parts of Agrimoniae;

[0042] The preparation method of the external hemostatic drug comprises the following steps:

[0043] Step 1) Raw material preparation: prepare Dalbergia odorifera, Eclipta prostrata, and Agrimonia scabra respectively according to weight parts;

[0044] Step 2) pulverizing: using a pulverizer to pulverize the dalbergia odorifera, eclipta herb, and agrimony, and sieving the pulverized raw materials respectively, the sieve is 100 mesh, and the dalbergia odorifera fine powder, eclipta herb fine powder, and agrimony fine powder can be obtained;

[0045] Step 3) uniformly mixing: stirring and mixing the obtained Dalbergia odorifera powder, Eclipta prostrata powder and Agrimoniae scabra powder to make the components fully and uniformly mixed;

[0046] Step 4) Sterilization: sterilize the mixed powder;

[0047] The sterilization treatment method is to use high temperature and high pressure steam sterilization, wherein the steam temperature is controlled at 134°C and the time is 30 minutes;

[0048] Step 5) Bottling and sealing: Put the sterilized powder into a clean bottle, seal it and store it away from light.

[0049] The present invention and its implementation methods are described above, and such description is not restrictive. In short, if ordinary technicians in the field are inspired by it, without departing from the purpose of the invention, they can design structures and embodiments similar to the technical solution without creativity, which should all fall within the protection scope of the present invention.

Claims

1. An external hemostatic drug, characterized in that: The invention comprises the following components in parts by weight: 10-20 parts of Dalbergia odorifera, 5-10 parts of Eclipta prostrata and 5-10 parts of Agrimoniae.

2. The external hemostatic drug according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 10 parts of Dalbergia odorifera, 5 parts of Eclipta prostrata and 5 parts of Agrimoniae.

3. The external hemostatic drug according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 16 parts of Dalbergia odorifera, 8 parts of Eclipta prostrata and 8 parts of Agrimoniae.

4. The external hemostatic drug according to claim 1, characterized in that: The invention comprises the following components in parts by weight: 20 parts of Dalbergia odorifera, 10 parts of Eclipta prostrata and 10 parts of Agrimoniae.

5. The method for preparing the external hemostatic drug according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1) Raw material preparation: prepare Dalbergia odorifera, Eclipta prostrata, and Agrimonia scabra respectively according to weight parts; Step 2) pulverizing: using a pulverizer to pulverize the dalbergia odorifera, eclipta prostrata, and agrimony, and sieving the pulverized raw materials respectively, the sieve having a mesh size of 80-100, to obtain dalbergia odorifera fine powder, eclipta prostrata fine powder, and agrimony fine powder; Step 3) uniformly mixing: stirring and mixing the obtained Dalbergia odorifera powder, Eclipta prostrata powder and Agrimoniae scabra powder to make the components fully and uniformly mixed; Step 4) Sterilization: sterilize the mixed powder; Step 5) Bottling and sealing: Put the sterilized powder into a clean bottle, seal it and store it away from light.

6. The preparation method according to claim 5, characterized in that: The sterilization treatment method in step 4 is to use high temperature and high pressure steam sterilization, wherein the temperature of the steam is controlled at 121-134° C. and the time is 15-30 minutes.