Wet granulation equipment with atomizing and spraying functions
By atomizing the adhesive in a wet granulation equipment and mixing it with the drug raw materials, the problem of uneven mixing of the adhesive and the drug raw materials in the prior art is solved, and the granulation efficiency and the stability of the particles are improved.
Patent Information
- Application Number
- CN202411384178.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-30
- Publication Date
- 2025-02-11
AI Technical Summary
The existing wet mixing granules machine is difficult to ensure uniform mixing of the adhesive and the drug raw materials when adding binders, resulting in the particles being easily dispersed and reducing the sustained release effect.
Atomizing spray wet granulation equipment is used to atomize the liquid adhesive and spray it into the granulation cylinder to mix it with the material, and uniform mixing is achieved by using agitating and shearing mechanism.
The mixing uniformity of drug raw materials and binder is improved, the stirring time required for the granulation equipment is reduced, and the working efficiency of the granulation equipment is improved.
Smart Images
Figure CN119406311A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of medical equipment, and in particular to a wet granulation equipment with atomization spray. Background Art
[0002] As a kind of equipment for pharmaceutical processing and granulation, wet granulator adds auxiliary materials (binders) to drug raw material powder and adds them into the granulator in appropriate proportion. The powder and binder are mixed and stirred at high speed in the granulator to form a wet soft material, which is then cut into uniform wet particles by the crushing paddle on the side wall of the granulator to complete the granulation. The powder is mainly gathered together by the bridging or bonding effect of the binder.
[0003] When adding binders, existing wet mixing granulators often have difficulty ensuring uniform mixing of binders and drug raw materials, which results in the granules being easily dispersed and reduces the sustained-release effect. In order to improve the mixing effect of binders and drug raw materials, some pharmaceutical companies usually increase the stirring time so that the binders and drug raw materials can fully contact and achieve uniform mixing. However, increasing the stirring time will increase the granulation time, which in turn affects the working efficiency of the granulator. Summary of the invention
[0004] The present application provides a wet granulation device with atomization spray, the purpose of which is to improve the uniformity of mixing of drug raw materials and adhesives, thereby reducing the stirring time required for the granulation device, thereby improving the working efficiency of the granulation device.
[0005] The present application provides an atomization spray wet granulation equipment adopts the following technical solution: A wet granulation device with atomizing spray comprises a granulation barrel, which is vertically arranged, and an upper cover is arranged on the upper end of the granulation barrel, the upper cover is detachably connected to the granulation barrel, and the upper cover seals the granulation barrel; a feeding mechanism, which is arranged on one side of the granulation barrel and is connected to the granulation barrel; a stirring mechanism, which is arranged on the inner bottom wall of the granulation barrel and is used to stir the material; a shearing mechanism, which is arranged on the inner side wall of the granulation barrel and is used to stir and shear the material; an atomizer, which comprises an atomizing nozzle, which is located in the granulation barrel, and the atomizing nozzle is connected to an air supply component and a liquid supply component; a respirator, which is arranged on the upper cover and is connected to the granulation barrel.
[0006] By adopting the above technical solution, the granulating barrel is used to contain the material, and the atomizer atomizes the liquid adhesive through the atomizing nozzle and sprays it into the material in the granulating barrel. During this process, the stirring mechanism and the shearing mechanism fully contact the material with the atomized adhesive and stir them evenly, thereby achieving granulation. After the granulation is completed, the granules prepared in the granulating barrel are sent out through the feeding mechanism. In addition, during this process, the respirator ensures that the air pressure inside and outside the granulating barrel is balanced to ensure the normal operation of the granulating barrel.
[0007] By atomizing the binder and adding it to the material, the material and the atomized binder are fully in contact, increasing the amount of material that the binder can contact. Then, under the synergistic effect of the stirring mechanism and the shearing mechanism, the uniformity of the mixing of the material and the binder can be improved, and the stirring time required for the granulating equipment can be reduced, thereby improving the working efficiency of the granulating equipment.
[0008] Optionally, a feeding port is formed through the upper cover, and a feeding cover is also provided on the upper cover. The feeding cover is detachably connected to the upper cover, and the feeding cover seals the feeding port.
[0009] By adopting the above technical solution, the matching arrangement of the feeding port and the feeding cover makes it easy to feed materials into the granulating barrel through the feeding port.
[0010] Optionally, the respirator includes a breathing tube, one end of which is connected to the upper cover, and the other end of which is provided with a filter element, the breathing tube is connected to the granulating cylinder, and the breathing tube is connected to the filter element.
[0011] By adopting the above technical solution, the breathing tube is arranged to connect the inner and outer spaces of the granulating cylinder, ensuring the normal flow of air, thereby realizing the pressure relief function and preventing excessive pressure in the granulating cylinder. The filter is arranged so that when the gas in the granulating cylinder is discharged through the breathing tube, the filter filters the gas, which can prevent the gas from carrying materials out of the granulating cylinder.
[0012] Optionally, the shearing mechanism comprises a shearing blade, wherein the shearing blade is located in the granulating barrel, the shearing blade is rotatably connected to the inner wall of the granulating barrel, and the shearing blade is coaxially connected to a shearing motor.
[0013] By adopting the above technical solution, the shearing mechanism can assist the stirring mechanism in stirring through the cooperation of the driving motor, the driving shaft and the shearing blades, and at the same time can realize the shearing function of the material, thereby facilitating the granulation of the material.
[0014] Optionally, the shearing blades include a driving shaft and a plurality of shearing blades, the driving shaft and the plurality of shearing blades are both located in the granulating barrel, one end of the driving shaft is rotatably connected to the inner wall of the granulating barrel, and the driving shaft is coaxially connected to a shearing motor; the plurality of shearing blades are spaced apart in sequence along the axial direction of the driving shaft, the length direction of the shearing blades is arranged along the radial direction corresponding to the driving shaft, and the length direction of the shearing blades is arranged perpendicular to the length direction of another adjacent shearing blade.
[0015] By adopting the above technical solution, the shear blade structure is set so that the shear blades are arranged in sequence along the axial direction of the drive shaft, and the length direction is perpendicular to another adjacent shear blade. This design can improve the shearing efficiency and ensure that the material is sheared evenly. In addition, the vertically arranged shear blades can better stir the material and improve the mixing effect of the material and the adhesive.
[0016] Optionally, the atomizer includes an atomizer tube, the atomizer tube is axially arranged in a vertical direction, and the atomizer nozzle is arranged at the lower end of the atomizer tube; a first hole is opened through the upper cover, the atomizer tube is plugged into the first hole, and the atomizer tube is slidably connected to the inner wall of the first hole along its own axis.
[0017] By adopting the above technical solution, the setting of the atomizing tube can realize the installation of the atomizing nozzle, and the atomizing tube is plugged and matched with the first hole, which is convenient for the installation and removal of the atomizer. The atomizing tube is slidably connected with the inner wall of the first hole along its own axial direction, which enables the atomizing tube to adjust its own position along its own length direction, and then adjust the height of the atomizing nozzle in the granulating barrel, so that the height of the atomizing nozzle can meet the requirements of different amounts of materials in the granulating barrel, thereby improving the scope of application of the granulating equipment of the present application.
[0018] Optionally, a locking assembly is provided on the atomizer tube, and the locking assembly is slidably connected to the atomizer tube along the axial direction of the atomizer tube; a first mounting seat is provided on the upper cover, and the locking assembly is detachably connected to the first mounting seat.
[0019] By adopting the above technical solution, the locking assembly and the first mounting seat are arranged in coordination, thereby achieving a detachable connection between the atomizer tube and the upper cover.
[0020] Optionally, a plurality of atomizing nozzles are provided, and the plurality of atomizing nozzles are arranged in sequence and at intervals along the circumference of the granulating cylinder.
[0021] By adopting the above technical solution, the atomizer can increase the coverage area of the atomized adhesive sprayed by the atomizer through the arrangement of multiple atomizing nozzles, ensuring that the materials at all locations in the granulation barrel can be evenly contacted with the atomized adhesive, which can improve the uniformity of the mixing of the materials and the adhesive. In addition, since the multiple atomizing nozzles are arranged in a circular pattern, the uniformity of the distribution of the atomized adhesive in the granulation barrel can be improved, which in turn helps to improve the uniformity of the mixing of the materials and the adhesive, thereby improving the granulation quality.
[0022] Optionally, the liquid supply component includes a liquid supply ring pipe, and the air supply component includes an air supply ring pipe, and the liquid supply ring pipe and the air supply ring pipe are both located in the granulation barrel, and the liquid supply ring pipe and the air supply ring pipe are both connected to the atomizing nozzle; the liquid supply ring pipe is connected to a plurality of straight liquid supply pipes, and the straight liquid supply pipes are arranged in a vertical direction, and the lower ends of the straight liquid supply pipes are connected to the liquid supply ring pipes, and the upper ends extend to the upper side of the upper cover; the air supply ring pipe is connected to a plurality of straight air supply pipes, and the straight air supply pipes are arranged in a vertical direction, and the lower ends of the straight air supply pipes are connected to the air supply ring pipes, and the upper ends extend to the upper side of the upper cover.
[0023] By adopting the above technical solution, since the liquid supply assembly fixes the liquid supply ring tube in the granulating barrel through a plurality of liquid supply straight tubes, and the upper end of the liquid supply straight tube extends to the upper side of the upper cover, liquid adhesive can be supplied to the liquid supply ring tube through the liquid supply straight tube. Similarly, the gas supply assembly fixes the gas supply ring tube in the granulating barrel through a plurality of gas supply straight tubes, and the upper end of the gas supply straight tube extends to the upper side of the upper cover, compressed gas can be supplied to the gas supply ring tube through the gas supply straight tube. Moreover, since the liquid supply ring tube and the gas supply ring tube are both connected to the atomizing nozzle, compressed gas and liquid adhesive can be provided to the atomizing nozzle, ensuring that the plurality of atomizing nozzles can work normally.
[0024] In summary, the present application includes at least one of the following beneficial technical effects: 1. The present application adopts the coordinated arrangement of a stirring mechanism, a shearing mechanism and an atomizer to atomize the adhesive and then add it to the material, so that the material is fully in contact with the atomized adhesive, thereby improving the uniformity of the mixing of the material and the adhesive, reducing the stirring time required for the granulation equipment, and thus improving the working efficiency of the granulation equipment.
[0025] 2. The present application can ensure the balance of air pressure inside and outside the granulation cylinder by setting a respirator, thereby ensuring the normal operation of the granulation cylinder, and at the same time preventing the gas from carrying materials out of the granulation cylinder.
[0026] 3. By providing multiple atomizing nozzles, the present application can increase the coverage area of the atomized adhesive sprayed by the atomizer, increase the uniformity of the distribution of the atomized adhesive in the granulation barrel, and further help to improve the uniformity of the mixing of the material and the adhesive, thereby improving the granulation quality. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] Figure 1 It is a schematic diagram of the overall structure of the granulation equipment of Example 1 of the present application.
[0028] Figure 2 It is a schematic diagram of the internal structure of the granulation cylinder of Example 1 of the present application.
[0029] Figure 3 yes Figure 1 Schematic diagram of the local enlarged structure of part A.
[0030] Figure 4 It is a schematic diagram of the overall structure of the upper cover of Example 1 of the present application.
[0031] Figure 5 It is a schematic diagram of the overall structure of the upper cover of Example 1 of the present application from another perspective.
[0032] Figure 6 It is a schematic diagram of the cross-sectional structure of the locking base of Example 1 of the present application.
[0033] Figure 7 It is a schematic diagram of the cross-sectional structure of the respirator of Example 1 of the present application.
[0034] Figure 8 It is a schematic diagram of the overall structure of the shear blade of Example 1 of the present application.
[0035] Fig. 9 It is a schematic diagram of the overall structure of the granulation equipment of Example 2 of the present application.
[0036] Fig.10 It is a schematic diagram of the overall structure of the upper cover of Example 2 of the present application.
[0037] Fig.11 It is a schematic diagram of the overall structure of the upper cover of Example 2 of the present application from another perspective.
[0038] In the figure, 1, operating table; 2, granulating cylinder; 21, upper cover; 211, feeding port; 212, feeding cover; 213, second stopper; 214, first hole; 215, first mounting seat; 216, second hole; 217, second mounting seat; 22, first stopper; 221, rotating handle; 222, rotating plate; 223, stopper plate; 23, locking assembly; 231, locking base; 232, locking nut; 233, locking sleeve; 3, feeding mechanism; 31, feeding pipe; 32, closed disc; 33, linear drive member; 34, feeding port; 4, stirring mechanism; 41, stirring blade; 5, shearing mechanism; 51, shearing blade; 511, driving shaft; 512, shearing blade; 6, atomizer ;61. Atomizing pipe;62. Atomizing nozzle;621. Connecting hose;63. Liquid supply assembly;630. First pipe;631. Liquid supply ring pipe;6311. First connecting hole;6312. First closing plug;632. Liquid supply straight pipe;633. Liquid supply hose;634. First connecting pipe;635. First closing cover;64. Air supply assembly;640. Second pipe;641. Air supply ring pipe;6411. Second connecting hole;6412. Second closing plug;642. Air supply straight pipe;643. Air supply hose;644. Second connecting pipe;645. Second closing cover;7. Respirator;71. Breathing pipe;72. Disc;721. Through hole;722. Air vent;73. Filter element;74. Housing. DETAILED DESCRIPTION
[0039] The following is combined with Figure 1 -Attached Fig.11 , further details of this application are given.
[0040] Embodiment 1: A kind of wet granulation equipment with atomization spray, referring to Figure 1 and Figure 2 , including an operating table 1, a granulating cylinder 2, a feeding mechanism 3, a stirring mechanism 4, a shearing mechanism 5, an atomizer 6 and a respirator 7. The granulating cylinder 2 is vertically arranged, and the granulating cylinder 2 is arranged on the operating table 1, and a control panel is also arranged on the operating table 1, the stirring mechanism 4 is arranged on the inner bottom wall of the granulating cylinder 2, the shearing mechanism 5 is arranged on the inner side wall of the granulating cylinder 2, the feeding mechanism 3 is arranged on one side of the granulating cylinder 2, and the feeding mechanism 3 is connected to the granulating cylinder 2, and an upper cover 21 is also arranged on the granulating cylinder 2, the upper cover 21 closes the granulating cylinder 2, and the upper cover 21 is detachably connected to the granulating cylinder 2, the atomizer 6 and the respirator 7 are both arranged on the upper cover 21, and the atomizer 6 and the respirator 7 are both connected to the granulating cylinder 2.
[0041] After the material is loaded into the granulating cylinder 2, the stirring mechanism 4 and the shearing mechanism 5 realize the stirring of the material, and the atomizer 6 atomizes the liquid adhesive and sprays it into the material. During the material stirring process, the material and the adhesive are fully contacted and gradually transformed into a soft material. The soft material is cut and gradually formed into granules under the action of the shearing mechanism 5 and the stirring mechanism 4, and finally the prepared granules are discharged through the unloading mechanism 3. During the above granulation process, the control panel controls the entire equipment. This can realize the wet granulation function.
[0042] Reference Figure 1 The upper cover 21 is rotatably connected to the operating table 1, and a hinge is provided between the upper cover 21 and the operating table 1. Such a structural arrangement enables the upper cover 21 to be rotated and opened on the operating table 1, thereby facilitating the closing or opening of the granulating cylinder 2.
[0043] Reference Figure 1 and Figure 3 A first limiting member 22 is also provided between the operating table 1 and the upper cover 21. The first limiting member 22 includes a rotating handle 221, a rotating plate 222 and a limiting plate 223. The limiting plate 223 is provided on the side wall of the upper cover 21. The rotating plate 222 is rotatably connected to the operating table 1, and one end of the length of the rotating handle 221 is fixedly connected to the rotating plate 222. The rotating plate 222 is located on the upper side of the limiting plate 223 in the vertical direction, and the upper side of the limiting plate 223 is slidably connected to the rotating plate 222. When the rotating plate 222 rotates to the upper side of the limiting plate 223, the rotating plate 222 limits the limiting plate 223, and the upper cover 21 cannot be opened at this time, so as to ensure that the upper cover 21 is sealed to the granulating cylinder 2. On the contrary, when the rotating plate 222 rotates to separate from the limiting plate 223, the rotating plate 222 no longer has a limiting function on the limiting plate 223, and the upper cover 21 can be opened at this time.
[0044] Reference Figure 1 and Figure 4 A feeding port 211 is formed through the upper cover 21 , and the feeding port 211 is communicated with the granulating cylinder 2 .
[0045] Reference Figure 4 and Figure 5 The upper cover 21 is provided with a feeding cover 212, which closes the feeding port 211, and the feeding cover 212 is detachably connected to the upper cover 21. Specifically, the feeding cover 212 is rotatably connected to the upper cover 21, and a hinge is provided between the feeding cover 212 and the upper cover 21; a second limiting member 213 is provided between the feeding cover 212 and the upper cover 21, and the first limiting member 22 and the second limiting member 213 have the same structure. The feeding cover 212 can open or close the feeding port 211 as needed, so that materials can be put into the granulating cylinder 2 through the feeding port 211.
[0046] Reference Figure 4 and Figure 5The atomizer 6 includes an atomizing tube 61, a liquid supply assembly 63 and an air supply assembly 64. A first hole 214 is formed through the upper cover 21. The atomizing tube 61 is vertically arranged and plugged into the first hole 214. The upper end of the atomizing tube 61 extends to the upper side of the upper cover 21, and the lower end extends into the granulating barrel 2. An atomizing nozzle 62 is arranged at the lower end of the atomizing tube 61. The liquid supply assembly 63 includes a first tube 630, and the air supply assembly 64 includes a second tube 640. The first tube 630 and the second tube 640 are both located at the upper end of the atomizing tube 61, and the first tube 630 and the second tube 640 are both connected to the atomizing tube 61.
[0047] Liquid adhesive is introduced through the first tube 630 , and compressed gas is introduced through the second tube 640 , so that the atomizer 6 can be loaded with materials, and the liquid adhesive can be atomized through the atomizing nozzle 62 .
[0048] Reference Figure 5 and Figure 6 The atomizer 6 further includes a locking assembly 23, which includes a locking base 231, a locking nut 232 and a locking sleeve 233. The locking base 231, the locking nut 232 and the locking sleeve 233 are all sleeved on the outside of the atomizer tube 61, the locking base 231 is sleeved on the outside of the locking sleeve 233, the locking nut 232 is sleeved on the outside of the locking base 231, the locking nut 232 is connected to the locking base 231 by threads, and the upper side of the locking sleeve 233 conflicts with the locking nut 232, and the lower side conflicts with the locking base 231. In this embodiment, the locking sleeve 233 is made of polytetrafluoroethylene.
[0049] When the locking nut 232 and the locking base 231 are relatively tightened, the locking sleeve 233 is deformed to clamp the atomizing tube 61, and the locking assembly 23 is fixed to the atomizing tube 61. On the contrary, when the locking nut 232 and the locking base 231 are relatively loosened, the locking sleeve 233 and the atomizing tube 61 are loosened, and the locking assembly 23 and the atomizing tube 61 can slide relative to each other.
[0050] Reference Figure 4 and Figure 5 The atomizing tube 61 is slidably connected with the inner wall of the first hole 214 along its own axial direction, or the outer wall of the atomizing tube 61 is spaced apart from the inner wall of the first hole 214. A first mounting seat 215 is provided on the upper cover 21, and the first mounting seat 215 is coaxially arranged with the first hole 214, and the first mounting seat 215 is sleeved on the outer side of the atomizing tube 61.
[0051] Reference Figure 5 and Figure 6The locking base 231 is arranged vertically opposite to the first mounting base 215, and the locking base 231 is connected to the first mounting base 215 via a clamp. Such a structural arrangement can realize a detachable connection between the atomizing tube 61 and the upper cover 21, and at the same time, by adjusting the position of the locking assembly 23 on the atomizing tube 61, the depth of the atomizing tube 61 inserted into the granulating barrel 2 can be changed.
[0052] Reference Figure 5 and Figure 7 The respirator 7 includes a breathing tube 71 and a disc 72. A through hole 721 is formed through the disc 72. The breathing tube 71 is arranged in a vertical direction. The lower end of the breathing tube 71 is connected to the upper cover 21, and the upper end of the breathing tube 71 is connected to the disc 72. The breathing tube 71 is coaxially connected to the through hole 721, and the breathing tube 71 is connected to the granulating cylinder 2.
[0053] Reference Figure 4 and Figure 5 The upper cover 21 is provided with a second hole 216, and the upper cover 21 is also provided with a second mounting seat 217, the second mounting seat 217 is coaxially arranged with the second hole 216, the breathing tube 71 is coaxially arranged with the second mounting seat 217, and the lower end of the breathing tube 71 is connected to the second mounting seat 217 via a clamp. Such a structural arrangement can realize a detachable connection between the breathing tube 71 and the upper cover 21.
[0054] Reference Figure 5 and Figure 7 The respirator 7 also includes a filter 73, and the filter 73 is cylindrical. A plurality of filter layers are arranged in sequence along the vertical direction in the filter 73, and the filter layers are made of filter nets, active springs or filter cotton. A joint is arranged on the disc 72, and the joint is fixedly connected to the disc 72. The joint is connected to the through hole 721, and the lower end of the filter 73 is plugged and matched with the joint. The filter 73 closes the through hole 721. When the pressure in the granulating cylinder 2 is too high, the gas in the granulating cylinder 2 will enter the filter 73 from the breathing tube 71. At this time, the filter 73 realizes gas filtration, and then can intercept the material powder carried by the gas to prevent the material from overflowing.
[0055] Reference Figure 5 and Figure 7 The respirator 7 further includes a shell 74, which is sleeved on the outside of the filter 73, and the lower end of the shell 74 contacts the disc 72, and the shell 74 and the disc 72 are connected by a clamp. The inner wall of the shell 74 is spaced apart from the outer wall of the filter 73, and a plurality of air holes 722 are formed through the disc 72, and the space between the inner wall of the shell 74 and the filter 73 is connected to the air holes 722. The setting of the shell 74 can realize dust protection of the filter 73, and the setting of the air holes 722 can also ensure the circulation of gas.
[0056] Reference Figure 2 The stirring mechanism 4 includes a stirring blade 41, which is arranged on the inner bottom wall of the granulating cylinder 2 and is rotatably connected to the granulating cylinder 2. A stirring motor is arranged in the operating table 1, and the output shaft of the stirring motor is coaxially connected to the stirring blade 41. The structural setting of the stirring mechanism 4 can achieve the stirring of the material.
[0057] Reference Figure 2 and Figure 8 The shearing mechanism 5 includes a shearing blade 51, which is arranged on the inner wall of the granulating cylinder 2 and is rotatably connected to the inner wall of the granulating cylinder 2. A shearing motor is arranged in the operating table 1, and the output shaft of the shearing motor is coaxially connected to the shearing blade 51. The setting of the shearing mechanism 5 can assist in stirring the material and shear the material at the same time.
[0058] Reference Figure 2 and Figure 8 The shearing blade 51 includes a driving shaft 511 and a plurality of shearing blades 512. The axial direction of the driving shaft 511 is arranged along the corresponding radial direction of the granulating cylinder 2. One end of the driving shaft 511 is rotatably connected to the inner wall of the granulating cylinder 2, and the output shaft of the shearing motor is coaxially connected to the driving shaft 511. The plurality of shearing blades 512 are arranged in sequence along the axial direction of the driving shaft 511. The length direction of the shearing blade 51 is arranged along the corresponding radial direction of the driving shaft 511, and the middle part of the shearing blade 51 along its own length direction is connected to the driving shaft 511. The length directions of two adjacent shearing blades 51 are arranged perpendicular to each other. The structural arrangement of the shearing blade 512 can improve the stirring and shearing effect of the material.
[0059] Reference Figure 2 and Figure 8 Both ends of the shear blade 512 in the length direction are bent toward the middle of the granulating cylinder 2. Such a structural arrangement can push the material toward the middle of the granulating cylinder 2, which can improve the stirring effect of the material.
[0060] Reference Figure 1 and Figure 2The feeding mechanism 3 includes a feeding tube 31, which is arranged in the horizontal direction, one end of which is connected to the side wall of the granulating cylinder 2, and the feeding tube 31 is in communication with the granulating cylinder 2. A closed disc 32 is arranged in the feeding tube 31, which closes the feeding tube 31, and the closed disc 32 is slidably connected to the inner side wall of the feeding tube 31 along its own axial direction. A linear driving member 33 is arranged on the feeding tube 31, and the linear driving member 33 adopts a cylinder or a hydraulic cylinder, and the driving end of the linear driving member 33 is coaxially connected to the closed disc 32. A discharge port 34 is opened at the lower side of the feeding tube 31. With such a structural arrangement, when granulation is being carried out, the closed disc 32 closes the discharge pipe 31, and granulation operation can be performed in the granulation barrel 2; and when granulation is completed, the closed disc 32 opens the discharge pipe 31, and at this time the discharge port 34 is connected to the granulation barrel 2 through the discharge pipe 31, and the particles in the granulation barrel 2 can be discharged from the discharge port 34, thereby realizing the discharge function.
[0061] The implementation principle of the embodiment of the present application is as follows: when the granulation operation is performed, the material is fed into the granulation barrel 2 through the feed port 211, and then the feed port 211 is closed. After that, the atomizer 6, the stirring mechanism 4 and the shearing mechanism 5 work synchronously, the stirring mechanism 4 and the shearing mechanism 5 stir and shear the material, the atomizer 6 atomizes the liquid adhesive and sprays it into the granulation barrel 2, then the atomized adhesive is in full contact with the material, and under the action of the atomizer 6, the stirring mechanism 4 and the shearing mechanism 5, the material gradually forms particles. When the granulation operation is completed, the atomizer 6 is closed, the unloading mechanism 3 is opened, and under the action of the unloading mechanism 3, the stirring mechanism 4 and the shearing mechanism 5, the particles in the granulation barrel 2 are gradually discharged from the unloading pipe 31, realizing the unloading function.
[0062] Embodiment 2: A kind of wet granulation equipment with atomization spray, referring to Fig. 9 and Fig.10 The difference between this embodiment and embodiment 1 is that the granulation equipment also includes an atomizer 6, the atomizer 6 includes an air supply component 64, a liquid supply component 63 and a plurality of atomizing nozzles 62, the plurality of atomizing nozzles 62 are all located in the granulation barrel 2, and the plurality of atomizing nozzles 62 are arranged in a circle, the air inlet pipe of the atomizing nozzle 62 is connected to the air supply component 64, and the liquid inlet pipe of the atomizing nozzle 62 is connected to the liquid supply component 63.
[0063] The air supply assembly 64 supplies compressed gas to the atomizing nozzle 62, and the liquid supply assembly 63 supplies liquid adhesive to the atomizing nozzle 62, so that the plurality of atomizing nozzles 62 can realize the spraying function. Since the plurality of atomizing nozzles 62 are arranged in a circle, the uniformity of the distribution of the atomized adhesive in various places in the granulating barrel 2 can be improved, and the uniformity of the mixing of the material and the adhesive can be improved. Similarly, since the number of atomizing nozzles 62 is large and the arrangement is uniform, the area covered by the atomizer 6 is large, and the area required to be covered by a single atomizing nozzle 62 is small, and the pressure of the compressed gas required to be used is small, and the air pressure of the compressed gas is reduced, so that the interference of the gas on the material powder can be reduced, and the lifting of the material powder can be reduced.
[0064] Reference Fig. 9 and Fig.10 The liquid supply assembly 63 includes a liquid supply ring pipe 631 and a plurality of liquid supply straight pipes 632. The plurality of liquid supply straight pipes 632 are arranged in the vertical direction. The liquid supply ring pipe 631 is located in the granulating cylinder 2, and the liquid supply ring pipe 631 is coaxially arranged with the granulating cylinder 2. The upper end of the liquid supply straight pipe 632 extends to the upper side of the upper cover 21, the lower end of the liquid supply straight pipe 632 is detachably connected to the liquid supply ring pipe 631, and the liquid supply straight pipe 632 is connected to the liquid supply ring pipe 631, and the upper end of the liquid supply straight pipe 632 is connected with a liquid supply hose 633.
[0065] Reference Fig. 9 and Fig.10 The air supply assembly 64 includes an air supply ring pipe 641 and a plurality of air supply straight pipes 642. The plurality of air supply straight pipes 642 are arranged in the vertical direction. The air supply ring pipe 641 is located in the granulating barrel 2, and the air supply ring pipe 641 is arranged coaxially with the granulating barrel 2. The upper end of the air supply straight pipe 642 extends to the upper side of the upper cover 21, the lower end of the air supply straight pipe 642 is detachably connected to the air supply ring pipe 641, and the air supply straight pipe 642 is connected to the air supply ring pipe 641. The upper end of the air supply straight pipe 642 is connected to the air supply ring pipe 641, and the upper end of the air supply straight pipe 642 is connected to the air supply hose 643. Compressed gas can be supplied to the air supply straight pipe 642 through the air supply hose 643, and then the compressed gas can be transported to the air supply ring pipe 641.
[0066] In this embodiment, the liquid supply ring pipe 631 and the air supply ring pipe 641 are located on the same horizontal plane, and both the liquid supply ring pipe 631 and the air supply ring pipe 641 are coaxially arranged with the granulating cylinder 2 , and the air supply ring pipe 641 is located inside the liquid supply ring pipe 631 .
[0067] Reference Fig.10 and Fig.11The outer sides of the liquid supply straight pipe 632 and the gas supply straight pipe 642 are sleeved with a locking assembly 23. A plurality of first holes 214 are provided on the upper cover 21, and a plurality of first mounting seats 215 are provided. The first holes 214, the first mounting seats 215 and the locking assembly 23 are provided in a one-to-one correspondence. The liquid supply straight pipe 632 and the gas supply straight pipe 642 are plug-fitted with the corresponding first holes 214, the first mounting seats 215 are coaxially provided with the corresponding first holes 214, and the locking assembly 23 is connected with the corresponding first mounting seats 215 through a clamp.
[0068] Since the locking assembly 23 can be fixed on the outside of the corresponding liquid supply straight pipe 632 or the air supply straight pipe 642, and can also slide axially along the corresponding liquid supply straight pipe 632 or the air supply straight pipe 642, and the locking assembly 23 can be fixed to the corresponding first mounting seat 215, the depth of the liquid supply straight pipe 632 and the air supply straight pipe 642 inserted into the granulation barrel 2 can be freely adjusted, and the height of the liquid supply ring pipe 631 and the air supply ring pipe 641 in the granulation barrel 2 can be adjusted.
[0069] Reference Fig. 9 and Fig.10 , a plurality of first connecting tubes 634 are arranged on the upper side of the liquid supply ring tube 631, the axial direction of the first connecting tube 634 is arranged along the vertical direction, and the lower end of the first connecting tube 634 is connected to the liquid supply ring tube 631. A plurality of first connecting tubes 634 are arranged in sequence along the circumference of the granulating cylinder 2. There are a plurality of first connecting tubes 634 arranged one-to-one with the liquid supply straight tube 632, the lower end of the liquid supply straight tube 632 is plugged with the corresponding first connecting tube 634, and the liquid supply straight tube 632 is connected to the corresponding first connecting tube 634 by threading. A plurality of first closing covers 635 are arranged on the liquid supply ring tube 631, there are a plurality of first connecting tubes 634 arranged one-to-one with the first closing covers 635, the first closing covers 635 are plugged with the corresponding first connecting tube 634, and the first closing covers 635 close the corresponding first connecting tube 634.
[0070] The first connecting tube 634 is provided to realize the detachable connection between the liquid supply ring tube 631 and the liquid supply straight tube 632. The first closing cap 635 is provided to close the unused first connecting tube 634 to prevent the liquid supply ring tube 631 from leaking.
[0071] Reference Fig. 9 and Fig.10, a plurality of second connecting pipes 644 are arranged on the upper side of the air supply ring pipe 641, the second connecting pipes 644 are arranged axially in the vertical direction, and the lower end of the second connecting pipe 644 is connected to the air supply ring pipe 641. A plurality of second connecting pipes 644 are arranged in sequence along the circumference of the granulating cylinder 2. There are a plurality of second connecting pipes 644 arranged one-to-one with the air supply straight pipe 642, the lower end of the air supply straight pipe 642 is plugged in with the corresponding second connecting pipe 644, and the air supply straight pipe 642 is connected to the corresponding second connecting pipe 644 by threads. A plurality of second closing covers 645 are arranged on the air supply ring pipe 641, there are a plurality of second connecting pipes 644 arranged one-to-one with the second closing covers 645, the second closing covers 645 are plugged in with the corresponding second connecting pipe 644, and the second closing covers 645 close the corresponding second connecting pipe 644.
[0072] The second connecting tube 644 realizes the detachable connection between the air supply ring tube 641 and the air supply straight tube 642. The second closing cover 645 can close the unused second connecting tube 644 to prevent the air supply ring tube 641 from leaking.
[0073] Reference Fig. 9 and Fig.11 A plurality of first connection holes 6311 are provided at the lower side of the liquid supply ring tube 631, and the plurality of first connection holes 6311 are sequentially spaced along the circumference of the granulating cylinder 2. A plurality of second connection holes 6411 are provided at the lower side of the air supply ring tube 641, and the plurality of second connection holes 6411 are sequentially spaced along the circumference of the granulating cylinder 2. The first connection holes 6311 and the second connection holes 6411 are arranged one by one.
[0074] Reference Fig. 9 and Fig.11 , there are a number of first connection holes 6311 arranged one-to-one with the atomizing nozzle 62, and the liquid inlet pipe of the atomizing nozzle 62 is plugged and matched with the corresponding first connection hole 6311. Specifically, the liquid inlet pipe of the atomizing nozzle 62 is connected to the inner wall of the corresponding first connection hole 6311 by threading. A connecting hose 621 is also provided between the atomizing nozzle 62 and the air supply ring pipe 641, one end of the connecting hose 621 is connected to the air inlet pipe corresponding to the atomizing nozzle 62, and the other end of the connecting hose 621 is plugged and matched with the corresponding second connection hole 6411. Specifically, the connecting hose 621 is connected to the inner wall of the corresponding second connection hole 6411 by threading.
[0075] Such a structural arrangement enables the liquid supply ring pipe 631 to supply liquid to the atomizing nozzle 62, and the air supply ring pipe 641 to supply air to the atomizing nozzle 62, thereby meeting the use requirements of the atomizing nozzle 62. At this time, since the connecting hose 621 is threadedly connected to the corresponding second connecting hole 6411, and the atomizing nozzle 62 is threadedly connected to the corresponding first connecting hole 6311, it is convenient to disassemble and replace the atomizing nozzle 62.
[0076] Reference Fig. 9 and Fig.11 , a plurality of first sealing plugs 6312 are provided on the liquid supply ring pipe 631, a plurality of first connection holes 6311 are provided in one-to-one correspondence with the first sealing plugs 6312, and the first sealing plugs 6312 are plugged and matched with the corresponding first connection holes 6311, and the first sealing plugs 6312 seal the corresponding first connection holes 6311. Similarly, a plurality of second sealing plugs 6412 are provided on the air supply ring pipe 641, a plurality of second connection holes 6411 are provided in one-to-one correspondence with the second sealing plugs 6412, and the second sealing plugs 6412 are plugged and matched with the corresponding second connection holes 6411, and the second sealing plugs 6412 seal the corresponding second connection holes 6411.
[0077] The first closing plug 6312 and the second closing plug 6412 cooperate to close the unused first connecting hole 6311 and the second connecting hole 6411 to prevent leakage of the liquid supply ring pipe 631 and the air supply ring pipe 641. With this structural arrangement, the number and arrangement of the atomizing nozzles 62 can be selected according to actual needs.
[0078] The implementation principle of the embodiment of the present application is: the setting of the atomizer 6 makes the atomizing nozzles 62 in the granulation barrel 2 arranged in a circular shape, which improves the coverage range of the atomizer 6, and improves the uniformity of the distribution of the atomized adhesive in various places in the granulation barrel 2, and improves the uniformity of the mixing of the material and the atomized adhesive in various places in the granulation barrel 2.
[0079] The embodiments of this specific implementation are all preferred embodiments of the present application, and are not intended to limit the protection scope of the present application. The same components are represented by the same figure marks. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the protection scope of the present application.
Claims
1. A wet granulation equipment with atomization spray, characterized in that: include: A granulating cylinder (2), the granulating cylinder (2) being arranged vertically, an upper cover (21) being arranged at the upper end of the granulating cylinder (2), the upper cover (21) being detachably connected to the granulating cylinder (2), and the upper cover (21) sealing the granulating cylinder (2); A material discharge mechanism (3), the material discharge mechanism (3) being arranged on one side of the granulating cylinder (2), and the material discharge mechanism (3) being in communication with the granulating cylinder (2); A stirring mechanism (4), the stirring mechanism (4) being arranged on the inner bottom wall of the granulating cylinder (2), and the stirring mechanism (4) being used to stir the material; A shearing mechanism (5), the shearing mechanism (5) being arranged on the inner side wall of the granulating cylinder (2), and the shearing mechanism (5) being used for stirring and shearing the material; an atomizer (6), the atomizer (6) comprising an atomizing nozzle (62), the atomizing nozzle (62) being located in the granulating barrel (2), the atomizing nozzle (62) being connected to an air supply component (64) and a liquid supply component (63); A respirator (7), wherein the respirator (7) is arranged on the upper cover (21), and the respirator (7) is connected to the granulating cylinder (2).
2. The wet granulation equipment with atomization spraying according to claim 1, characterized in that: The upper cover (21) is provided with a loading port (211) extending therethrough, and the upper cover (21) is also provided with a loading cover (212), the loading cover (212) being detachably connected to the upper cover (21), and the loading cover (212) is sealed with the loading port (211).
3. The wet granulation equipment with atomization spraying according to claim 1, characterized in that: The respirator (7) comprises a breathing tube (71), one end of the breathing tube (71) is connected to the upper cover (21), and the other end is provided with a filter element (73), the breathing tube (71) is in communication with the granulating cylinder (2), and the breathing tube (71) is in communication with the filter element (73).
4. The wet granulation equipment with atomization spraying according to claim 1, characterized in that: The shearing mechanism (5) comprises a shearing blade (51), the shearing blade (51) being located in the granulating cylinder (2), the shearing blade (51) being rotatably connected to the inner wall of the granulating cylinder (2), and the shearing blade (51) being coaxially connected to a shearing motor.
5. The wet granulation equipment with atomization spraying according to claim 4, characterized in that: The shear blade (51) comprises a drive shaft (511) and a plurality of shear blades (512), the drive shaft (511) and the plurality of shear blades (512) are both located in the granulating cylinder (2), one end of the drive shaft (511) is rotatably connected to the inner wall of the granulating cylinder (2), and the drive shaft (511) is coaxially connected to a shear motor; A plurality of the shear blades (512) are arranged in sequence and spaced apart along the axial direction of the driving shaft (511); the length direction of the shear blades (512) is arranged along the radial direction corresponding to the driving shaft (511); and the length direction of the shear blades (512) is arranged perpendicular to the length direction of another adjacent shear blade (512).
6. The wet granulation equipment with atomization spraying according to claim 1, characterized in that: The atomizer (6) comprises an atomizing tube (61), the atomizing tube (61) is axially arranged in a vertical direction, and the atomizing nozzle (62) is arranged at the lower end of the atomizing tube (61); The upper cover (21) is provided with a first hole (214) extending therethrough, the atomizing tube (61) is plug-fitted into the first hole (214), and the atomizing tube (61) is slidably connected to the inner wall of the first hole (214) along its own axial direction.
7. The wet granulation equipment with atomization spraying according to claim 6, characterized in that: The atomizer tube (61) is provided with a locking assembly (23), and the locking assembly (23) is slidably connected to the atomizer tube (61) along the axial direction of the atomizer tube (61); A first mounting seat (215) is provided on the upper cover (21), and the locking assembly (23) is detachably connected to the first mounting seat (215).
8. The wet granulation equipment with atomization spraying according to claim 1, characterized in that A plurality of the atomizing nozzles (62) are provided, and the plurality of the atomizing nozzles (62) are arranged in sequence and at intervals along the circumference of the granulating barrel (2).
9. The wet granulation equipment with atomization spraying according to claim 8, characterized in that: The liquid supply assembly (63) comprises a liquid supply ring pipe (631), and the air supply assembly (64) comprises an air supply ring pipe (641). Both the liquid supply ring pipe (631) and the air supply ring pipe (641) are located in the granulating cylinder (2), and both the liquid supply ring pipe (631) and the air supply ring pipe (641) are in communication with the atomizing nozzle (62); The liquid supply ring pipe (631) is connected to a plurality of liquid supply straight pipes (632), the liquid supply straight pipes (632) are arranged in a vertical direction, and the lower ends of the liquid supply straight pipes (632) are connected to the liquid supply ring pipe (631), and the upper ends extend to the upper side of the upper cover (21); The air supply ring pipe (641) is connected to a plurality of air supply straight pipes (642), the air supply straight pipes (642) are arranged in a vertical direction, and the lower ends of the air supply straight pipes (642) are connected to the air supply ring pipe (641), and the upper ends extend to the upper side of the upper cover (21).