Nutritional composition with sleep-aiding and nerve-calming effects and application thereof
By using a nutritional composition with a specific ratio, combined with preparation steps such as crushing, drying, soaking, and fermenting, the problem of degradation in sleep quality in modern society is solved, and the effect of helping sleep and calming the mind, improving blood circulation and improving immunity is achieved.
Patent Information
- Application Number
- CN202411732003.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-29
- Publication Date
- 2025-02-14
AI Technical Summary
The pace of life in modern society has accelerated, resulting in the delay in sleeping time for residents, shortening of sleep duration, decreasing quality of sleep, and problems such as light sleep, difficulty falling asleep, and easy awakening, affecting physical health and quality of life.
It adopts a nutritional composition composed of Poria, Amomum villosa, cypress kernel, white cardamom, Salvia miltiorrhiza, Moringa seed, ginger yolk, bay powder, Shenqu, krill peptide powder, shea butter and Eucommia seed oil. Prepare into powder or other easy-to-use forms by specific preparation methods, including crushing, sun drying, soaking, fermenting and crushing and dispersing.
This nutritional composition can coordinate sleep assistance, and has the effects of calming the heart and calming the mind, eliminating dampness and promoting qi, improving blood circulation and improving human immunity, and deeply improving sleep quality and improving quality of life.
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Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of biological food, and in particular to a nutrient composition having sleep-promoting and tranquilizing effects and application thereof. Background Art
[0002] As the pace of life in modern society accelerates and work intensity increases, residents are going to bed later, sleeping time is shortening, and sleep quality is also declining significantly. According to the survey, more than 60% of residents go to bed after 23:00, and more than 90% of residents often or occasionally have sleep quality problems. Among the sleep quality problems of residents, shallow sleep, difficulty falling asleep, easy awakening and other problems have become the main problems that bother the people. Sleep quality problems can cause reduced physical vitality, poor skin condition, decreased memory, emotional instability, and decreased physical fitness.
[0003] Therefore, in recent years, the society as a whole has further deepened its attention to sleep health, and more groups have begun to improve their sleep quality by purchasing sleep aids. However, there are a wide variety of sleep aids on the market, and the market is in urgent need of a product that can deeply improve sleep and is green and healthy. Summary of the invention
[0004] In view of the deficiencies in the prior art, the present invention provides a nutrient composition with sleep-inducing and tranquilizing effects and its application, which can synergistically aid sleep, and has the effects of tranquilizing the mind, removing dampness and promoting qi, improving blood circulation, and enhancing human immunity.
[0005] The above technical objectives of the present invention are achieved through the following technical solutions:
[0006] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0007] 87-105 parts of Poria, 87-105 parts of Amomum villosum, 45-68 parts of Platycladus orientalis, 45-68 parts of White Cardamom, 35-55 parts of Salvia miltiorrhiza, 87-105 parts of Moringa seeds, 45-68 parts of Ligusticum chuanxiong, 50-70 parts of Panax notoginseng, 50-70 parts of Shenqu, 25-35 parts of krill peptide powder, 2-5 parts of Shea butter, and 2-5 parts of Eucommia seed oil.
[0008] Furthermore, the nutritional composition is prepared from the following raw materials in weight ratio:
[0009] 97 parts of Poria, 97 parts of Amomum villosum, 58 parts of Platycladus orientalis, 58 parts of White Cardamom, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 58 parts of Ligusticum chuanxiong, 65 parts of Pandanus officinalis, 65 parts of Shenqu, 30 parts of Krill Peptide Powder, 3.5 parts of Shea Butter, and 3.5 parts of Eucommia Seed Oil.
[0010] Furthermore, the preparation method of the nutritional composition comprises the following steps:
[0011] S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to use as main raw materials; dissolving 1.0-1.5% salt, 1.0-1.5% sugar and 0.5-1.0% edible alkali in rice water, and then soaking the main raw materials for 8-15 hours, taking them out and drying them in the sun;
[0012] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0013] S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 100-150 minutes, and then cooling;
[0014] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 7-10 days.
[0015] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0016] Furthermore, the powdered nutritional composition is processed with auxiliary materials acceptable in food science to produce a product suitable for consumption.
[0017] Furthermore, the nutritional composition is processed into forms including but not limited to tablets, capsules, pills, granules, and powders.
[0018] The present invention also provides an application of the above-mentioned nutritional composition in preparing a food for promoting sleep and calming the nerves.
[0019] The present invention prepares nutritional composition with Poria, Fructus Amomi, Semen Platycladi, White Cardamom, Salvia miltiorrhiza, Moringa seeds, Ligusticum chuanxiong, Pandan powder, Shenqu, Krill peptide powder, Shea butter, Eucommia seed oil as raw materials, after being combined by each component, can coordinate sleep aid, has the effects of tranquilizing the mind, removing dampness and promoting qi, improving blood circulation, improving human immunity, etc. And in the preparation step, each component in the main raw material can be softened by fiber after being pretreated by the main raw material, which contributes to the release of ingredients and further improves the subsequent fermentation effect. The nutritional composition provided in the present invention can also be processed into various products that are easy to take, and has good application value. DETAILED DESCRIPTION
[0020] The technical scheme of the present invention is further described below in conjunction with embodiments and comparative examples.
[0021] Embodiment 1:
[0022] A nutrient composition with sleep-promoting and calming effects, prepared from the following raw materials in the following weight ratios:
[0023] 87 parts of Poria, 105 parts of Amomum villosum, 45 parts of Platycladus orientalis, 68 parts of White Cardamom, 35 parts of Salvia miltiorrhiza, 105 parts of Moringa seeds, 45 parts of Ligusticum chuanxiong, 70 parts of Panax notoginseng, 50 parts of Shenqu, 35 parts of Krill Peptide Powder, 2 parts of Shea Butter, and 2 parts of Eucommia Seed Oil.
[0024] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0025] S1, crushing Poria, Amomum villosum, Salvia miltiorrhiza, Platycladus orientalis seeds, White cardamom, Ligusticum chuanxiong and Moringa oleifera seeds into rough blocks and drying them in the sun to prepare the main raw materials; dissolving 1.0% salt, 1.0% sugar and 0.5% edible alkali in rice water, and then soaking the main raw materials for 8 hours, taking them out and drying them in the sun;
[0026] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0027] S3, using rice wine as a water source, steaming the main raw material soaked and dried in step S1 at high temperature for 100 minutes, and then cooling;
[0028] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 7 days.
[0029] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0030] The nutritional composition is formed into tablets by compression.
[0031] Embodiment 2:
[0032] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0033] 105 parts of Poria, 87 parts of Amomum villosum, 68 parts of Platycladus orientalis, 45 parts of White Cardamom, 55 parts of Salvia miltiorrhiza, 87 parts of Moringa seeds, 68 parts of Ligusticum chuanxiong, 50 parts of Pandanus officinalis, 70 parts of Shenqu, 25 parts of Krill Peptide Powder, 5 parts of Shea Butter, and 5 parts of Eucommia Seed Oil.
[0034] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0035] S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to serve as the main raw materials; dissolving 1.5% salt, 1.5% sugar and 1.0% edible alkali in rice water, and then soaking the main raw materials for 15 hours, taking them out and drying them in the sun;
[0036] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0037] S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 150 minutes, and then cooling;
[0038] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 10 days.
[0039] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0040] The nutritional composition is further crushed and dispersed to form a powder.
[0041] Embodiment 3:
[0042] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0043] 97 parts of Poria, 97 parts of Amomum villosum, 58 parts of Platycladus orientalis, 58 parts of White Cardamom, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 58 parts of Ligusticum chuanxiong, 65 parts of Pandanus officinalis, 65 parts of Shenqu, 30 parts of Krill Peptide Powder, 3.5 parts of Shea Butter, and 3.5 parts of Eucommia Seed Oil.
[0044] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0045] S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to serve as the main raw materials; dissolving 1.5% salt, 1.5% sugar and 1.0% edible alkali in rice water, and then soaking the main raw materials for 15 hours, taking them out and drying them in the sun;
[0046] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0047] S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 150 minutes, and then cooling;
[0048] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 10 days.
[0049] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0050] The nutritional composition is further crushed and dispersed to form a powder.
[0051] Embodiment 4:
[0052] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0053] 87 parts of Poria, 87 parts of Amomum villosum, 45 parts of Platycladus orientalis seeds, 45 parts of White Cardamom, 35 parts of Salvia miltiorrhiza, 87 parts of Moringa seeds, 45 parts of Ligusticum chuanxiong, 50 parts of Pandanus officinalis, 50 parts of Shenqu, 20 parts of Krill Peptide Powder, 3.5 parts of Shea butter, and 3.5 parts of Eucommia seed oil.
[0054] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0055] S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to serve as the main raw materials; dissolving 1.5% salt, 1.5% sugar and 1.0% edible alkali in rice water, and then soaking the main raw materials for 15 hours, taking them out and drying them in the sun;
[0056] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0057] S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 150 minutes, and then cooling;
[0058] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 10 days.
[0059] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0060] The nutritional composition is prepared into pills by adding appropriate bonding auxiliary materials.
[0061] Comparative Example 1:
[0062] In Comparative Example 1, the fermentation material and the fermentation step are removed, and the remaining steps are the same as those in Example 3. That is:
[0063] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0064] 97 parts of Poria, 97 parts of Amomum villosum, 58 parts of Platycladus orientalis, 58 parts of White Cardamom, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 58 parts of Ligusticum chuanxiong, 30 parts of krill peptide powder, 3.5 parts of Shea butter, and 3.5 parts of Eucommia seed oil.
[0065] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0066] S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to serve as the main raw materials; dissolving 1.5% salt, 1.5% sugar and 1.0% edible alkali in rice water, and then soaking the main raw materials for 15 hours, taking them out and drying them in the sun;
[0067] S2, using rice wine as a water source, steaming the main raw material soaked and dried in step S1 at high temperature for 150 minutes, and then spreading it to cool;
[0068] S3, drying the product in step S2 and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0069] The nutritional composition is further crushed and dispersed to form a powder.
[0070] Comparative Example 2:
[0071] In Comparative Example 2, the addition of shea butter and eucommia seed oil in the preparation step is removed, and the remaining steps are the same as those in Example 3. That is:
[0072] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0073] 97 parts of Poria, 97 parts of Amomum villosum, 58 parts of Platycladus orientalis, 58 parts of White Cardamom, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 58 parts of Ligusticum chuanxiong, 65 parts of Panax notoginseng, 65 parts of Shenqu, and 30 parts of krill peptide powder.
[0074] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0075] S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to serve as the main raw materials; dissolving 1.5% salt, 1.5% sugar and 1.0% edible alkali in rice water, and then soaking the main raw materials for 15 hours, taking them out and drying them in the sun;
[0076] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0077] S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 150 minutes, and then cooling;
[0078] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 10 days.
[0079] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and finally preparing a powdered nutritional composition.
[0080] The nutritional composition is further crushed and dispersed to form a powder.
[0081] Comparative Example 3:
[0082] In Comparative Example 3, the main raw materials of cypress seeds, white cardamom and cyperus rotundus were removed, and the krill peptide powder in the crushing and dispersion process was removed, and the remaining steps were the same as those in Example 3. That is:
[0083] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0084] 97 parts of Poria, 97 parts of Amomum villosum, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 65 parts of Panax notoginseng, 65 parts of Shenqu, 3.5 parts of Shea butter, and 3.5 parts of Eucommia seed oil.
[0085] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0086] S1, crushing Poria, Amomum villosum, Salvia miltiorrhiza, and Moringa seeds into rough blocks and drying them in the sun to prepare the main raw materials; dissolving 1.5% salt, 1.5% sugar, and 1.0% edible alkali in rice water, and then soaking the main raw materials for 15 hours, taking them out, and drying them in the sun;
[0087] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0088] S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 150 minutes, and then cooling;
[0089] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 10 days.
[0090] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, and simultaneously adding shea butter and eucommia seed oil dropwise during the crushing and dispersion process, so as to finally prepare a powdered nutritional composition.
[0091] The nutritional composition is further crushed and dispersed to form a powder.
[0092] Comparative Example 4:
[0093] In Comparative Example 4, the soaking step of the main raw materials in rice water is eliminated, and the remaining steps are the same as those in Example 3. That is:
[0094] A nutrient composition having a sleep-inducing and calming effect, the nutrient composition is prepared from the following raw materials in the following weight ratios:
[0095] 97 parts of Poria, 97 parts of Amomum villosum, 58 parts of Platycladus orientalis, 58 parts of White Cardamom, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 58 parts of Ligusticum chuanxiong, 65 parts of Pandanus officinalis, 65 parts of Shenqu, 30 parts of Krill Peptide Powder, 3.5 parts of Shea Butter, and 3.5 parts of Eucommia Seed Oil.
[0096] The method for preparing the nutritional composition in this embodiment comprises the following steps:
[0097] S1, crushing poria, amomum villosum, salvia miltiorrhiza, cypress seed, white cardamom, zingiber officinale and moringa seeds into rough blocks and drying them in the sun as the main raw materials;
[0098] S2, grinding the Shenqu into powder, and evenly mixing it with the pandan powder as a fermentation material;
[0099] S3, using rice wine as a water source, steaming the main raw materials in step S1 at high temperature for 150 minutes, and then cooling;
[0100] S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 10 days.
[0101] S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
[0102] The nutritional composition is further crushed and dispersed to form a powder.
[0103] The differences between Examples 1-4 and Comparative Examples 1-4 are shown in Table 1 below.
[0104] Table 1. Raw material ratio and link comparison table of Examples 1-4 and Comparative Examples 1-4
[0105]
[0106] The beneficial effects of the present invention are further illustrated by comparative experiments below.
[0107] 1. Selection of experimental individuals
[0108] A number of 6-week-old male C57BL / 6 mice were selected and fed stably under the same conditions of 24-26°C and 40-50% humidity for 1 week, and then 90 mice weighing 18±1g were selected. The 90 mice were randomly divided into 9 experimental groups, marked as experimental groups 1-9, with 10 mice in each experimental group.
[0109] 2. Experimental process
[0110] 1. Preparation of feeding agent
[0111] The tablet nutritional composition of Example 1 of this scheme is crushed and uniformly mixed with water to form a feeding agent, wherein the weight ratio of the nutritional composition to water is 1:2.
[0112] The powdered nutrient compositions of Examples 2-4 and Comparative Examples 1-4 in this solution were mixed with water to form feeding agents, wherein the weight ratio of the nutrient composition to water was 1:2.
[0113] 2. Experimental environment and classification of experimental groups
[0114] The mice in the nine experimental groups were fed with standard feed at a temperature of 27-29°C and a humidity of 40-50%. The feeding box was equipped with multiple compartments, and each mouse was in a separate compartment. The lighting time in the feeding box was alternating between light and dark every 4 hours, and the light intensity was fixed at 350-400 lux when the light was on.
[0115] In addition to the standard feed, the mice in experimental groups 1-8 were gavaged with the above feed every day, and the amount of food given was calculated based on a clear fixed amount, all of which were 0.4 ml. In addition to the standard feed, experimental group 9 was used as a blank control group, and the mice in experimental group 9 were gavaged with an equal amount of water every day. The mice in experimental groups 1-9 were gavaged for 6 consecutive weeks, and the gavage was performed at the beginning of the alternating light. The specific experimental group classification is shown in Table 2 below.
[0116] Table 2. Classification of oral administration in each experimental group
[0117]
[0118] 3. Experimental Monitoring Content
[0119] 1. Monitoring of the vital status of mice
[0120] During the experimental feeding period, the appearance of mice in each experimental group was observed every day, the weight of mice in each experimental group was tested every week, and the average weight of each experimental group was recorded.
[0121] The monitoring records are as follows:
[0122] (1) The appearance of the mice was observed during the six weeks of continuous gavage. The mice in experimental groups 1-9 had no external injuries, abnormal hair loss, rickets, lumps in the body, abnormal breathing or tremors, and their appearance was normal.
[0123] (2) During the six weeks of continuous gavage, the weight of mice in each experimental group was measured every week, and the average weight of each experimental group was recorded as follows:
[0124] The average body weight of experimental group 1 was 19.3 g at the end of the first week, 21.6 g at the end of the second week, 23.5 g at the end of the third week, 25.1 g at the end of the fourth week, 26.6 g at the end of the fifth week, and 27.9 g at the end of the sixth week.
[0125] The average body weight of experimental group 2 was 19.3 g at the end of the first week, 21.1 g at the end of the second week, 23.4 g at the end of the third week, 24.7 g at the end of the fourth week, 25.9 g at the end of the fifth week, and 27.7 g at the end of the sixth week.
[0126] The average body weight of experimental group 3 was 18.9 g at the end of the first week, 21.3 g at the end of the second week, 23.6 g at the end of the third week, 25.1 g at the end of the fourth week, 26.7 g at the end of the fifth week, and 28.1 g at the end of the sixth week.
[0127] The average body weight of experimental group 4 was 18.7 g at the end of the first week, 20.9 g at the end of the second week, 23.2 g at the end of the third week, 24.6 g at the end of the fourth week, 26.1 g at the end of the fifth week, and 27.6 g at the end of the sixth week.
[0128] The average body weight of experimental group 5 was 19.1 g at the end of the first week, 20.7 g at the end of the second week, 22.7 g at the end of the third week, 22.9 g at the end of the fourth week, 23.8 g at the end of the fifth week, and 23.7 g at the end of the sixth week.
[0129] The average body weight of experimental group 6 was 18.9 g at the end of the first week, 20.6 g at the end of the second week, 22.5 g at the end of the third week, 23.1 g at the end of the fourth week, 24.3 g at the end of the fifth week, and 24.7 g at the end of the sixth week.
[0130] The average body weight of experimental group 7 was 19.3 g at the end of the first week, 20.8 g at the end of the second week, 22.2 g at the end of the third week, 23.2 g at the end of the fourth week, 24.1 g at the end of the fifth week, and 24.3 g at the end of the sixth week.
[0131] The average body weight of experimental group 8 was 18.8 g at the end of the first week, 20.6 g at the end of the second week, 22.9 g at the end of the third week, 24.5 g at the end of the fourth week, 24.9 g at the end of the fifth week, and 25.5 g at the end of the sixth week.
[0132] The average body weight of experimental group 9 was 19.2 g at the end of the first week, 19.8 g at the end of the second week, 19.9 g at the end of the third week, 21.9 g at the end of the fourth week, 22.5 g at the end of the fifth week, and 22.9 g at the end of the sixth week.
[0133] The above records are shown in Table 3 below.
[0134] Table 3. Average body weight of mice in experimental groups 1-9 during 6 weeks of oral feeding
[0135]
[0136] 2. Sleep time detection experiment of mice
[0137] From the third week of gavage to the end of the fifth week, the sleep time detection experiment of mice was carried out. 90 minutes after the last gavage at the end of each weekend, sodium pentobarbital (50 mg / kg) was injected into the peritoneum of mice in each experimental group. The surrounding environment was in a bright state during the injection. The disappearance of the righting reflex was used as the sleep time point of the mice, and the recovery of the righting reflex was used as the awakening time point of the mice. After removing the highest and lowest values of each group, the average single sleep time of mice in each experimental group was recorded, as shown in Table 4 below.
[0138] Table 4. Average sleep time of mice in experimental groups 1-9
[0139]
[0140] 3. Sleep depth detection experiment of mice
[0141] (Test 1)
[0142] From the third week of gavage to the end of the fifth week, the sleep depth detection experiment of mice was carried out. After 90 minutes of the last gavage at the weekend, sodium pentobarbital (50mg / kg) was injected into the peritoneal cavity of each experimental group of mice. During injection, the surrounding environment was in a light state, with the disappearance of the righting reflex as the sleeping time point of mice, and the recovery of the righting reflex as the waking time point of mice. The number of activities of mice in the average of every 10 minutes during sleep was recorded, and the number of activities was included in the spontaneous swing of the four limbs of mice, the spontaneous swing of the tail of mice, the spontaneous swing of the head of mice, the change of the sleeping posture of mice, the body twitching during sleep, etc. The detection records are shown in Table 5 below. When the table cannot be divided, a decimal is taken.
[0143] Table 5. Average number of activities per 10 minutes during sleep of mice in experimental groups 1-9
[0144]
[0145] (Test 2)
[0146] The sleep depth detection experiment of mice was carried out at the end of the sixth week of gavage. 90 minutes after the last gavage at the end of the sixth week, sodium pentobarbital (50 mg / kg) was injected into the peritoneal cavity of each experimental group of mice. The surrounding environment was in a bright state during injection, and the disappearance of the righting reflex was used as the sleeping time point of the mice. After the mice fell asleep, 65dB white noise was applied to the environment, and the recovery of the righting reflex was used as the waking time point of the mice. The average time between each mouse falling asleep and being awakened in each experimental group was recorded. The detection records are shown in Table 6 below.
[0147] Table 5. Average time of awakening during sleep of mice in experimental groups 1-9
[0148]
[0149] 4. Experimental Conclusion
[0150] The appearance of the mice during feeding showed that the nutritional composition of the present invention was non-toxic under the experimental conditions and had no adverse effects on the experimental mice. The weight of the mice after six weeks of continuous gavage showed that the technical solution of the present application could effectively aid digestion, regulate the vitality and immunity of the organism, enhance the physical condition of the organism, and promote the healthy and rapid growth of the organism.
[0151] It can be seen from the sleep time detection experiment of mice that experimental group 9 is a blank control group, indicating that under the environmental conditions of the feeding box, especially the alternating light and dark lighting settings, the sleep quality of mice will be reduced and the normal growth and development of mice will be affected. By comparing the data of experimental groups 1-4 and experimental groups 5-8, the technical schemes of embodiments 1-4 provided by the present invention can effectively improve the sleep ability of mice and increase the sleep time of mice, and the sleep time of mice in experimental groups 1-4 is getting longer and longer from the third week to the fifth week, indicating that the nutritional composition of this scheme also has the effect of improving sleep.
[0152] From the sleep depth detection experiment of mice (experiment 1), it can be seen that through the data comparison of experimental groups 1-4, experimental groups 5-8 and experimental group 9, in experimental groups 1-4, the average number of activities of mice after falling asleep is less, which is significantly lower than the blank control group of experimental group 9; in experimental groups 5-8, the average number of activities of mice after falling asleep is still more. This shows that the nutritional composition of this scheme can improve sleep quality and deepen sleep depth.
[0153] From the sleep depth detection experiment of mice (experiment 2), it can be seen that through the data comparison of experimental groups 1-4, experimental groups 5-8 and experimental group 9, in experimental groups 1-4, the average time of mice being awakened by noise after falling asleep was longer, which was significantly improved compared with the blank control group of experimental group 9; in experimental groups 5-8, the average time of mice being awakened by noise after falling asleep was still shorter. It can also further illustrate that the nutritional composition in this scheme can effectively improve sleep quality and has a calming effect.
[0154] Finally, it should be noted that the above embodiments and comparative examples are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the present invention, which should be included in the scope of the claims of the present invention.
Claims
1. A nutritional composition having a sleep-inducing and calming effect, characterized in that: The nutritional composition is prepared from the following raw materials in the following weight ratio: 87-105 parts of Poria, 87-105 parts of Amomum villosum, 45-68 parts of Platycladus orientalis, 45-68 parts of White Cardamom, 35-55 parts of Salvia miltiorrhiza, 87-105 parts of Moringa seeds, 45-68 parts of Ligusticum chuanxiong, 50-70 parts of Panax notoginseng, 50-70 parts of Shenqu, 25-35 parts of krill peptide powder, 2-5 parts of Shea butter, and 2-5 parts of Eucommia seed oil.
2. A nutritional composition having a sleep-inducing and tranquilizing effect according to claim 1, characterized in that: The nutritional composition is prepared from the following raw materials in the following weight ratio: 97 parts of Poria, 97 parts of Amomum villosum, 58 parts of Platycladus orientalis, 58 parts of White Cardamom, 45 parts of Salvia miltiorrhiza, 97 parts of Moringa seeds, 58 parts of Ligusticum chuanxiong, 65 parts of Pandanus officinalis, 65 parts of Shenqu, 30 parts of Krill Peptide Powder, 3.5 parts of Shea Butter, and 3.5 parts of Eucommia Seed Oil.
3. The nutritional composition having sleep-inducing and tranquilizing effects according to claim 1, characterized in that: The preparation method of the nutritional composition comprises the following steps: S1, crushing poria, spring amomum, salvia miltiorrhiza, cypress seed, white cardamom, elm leaf and moringa seed into rough blocks and drying them in the sun to use as main raw materials; dissolving 1.0-1.5% salt, 1.0-1.5% sugar and 0.5-1.0% edible alkali in rice water, and then soaking the main raw materials for 8-15 hours, taking them out and drying them in the sun; S2, grind the Shenqu into powder, and mix it evenly with the pandan powder as a fermentation material; S3, using rice wine as a water source, steaming the main raw materials soaked and dried in step S1 at high temperature for 100-150 minutes, and then cooling; S4, adding fermentation material to the main raw materials after cooling in step S3, stirring evenly and putting into earthenware jars for fermentation, each jar is filled to two-thirds, the jar mouth is tightly covered and sealed, and placed in a cool, ventilated and dry place for 7-10 days. S5, taking out the product fermented in step S4, drying it, and crushing it into fine powder, adding krill peptide powder during the crushing and dispersion process, and dropping shea butter and eucommia seed oil while crushing and dispersing, and finally preparing a powdered nutritional composition.
4. A nutritional composition having sleep-inducing and tranquilizing effects according to any one of claims 1 to 3, characterized in that: The powdered nutritional composition is processed into an edible product by adding auxiliary materials acceptable to food science.
5. The nutritional composition having the effects of promoting sleep and calming nerves according to claim 4, characterized in that: The nutritional composition is processed into forms including but not limited to tablets, capsules, pills, granules, and powders.
6. Use of the nutritional composition according to any one of claims 1 to 3 in preparing a food for aiding sleep and calming the nerves.