Wearable medicine curative effect monitoring equipment

Abstract

The invention relates to the technical field of drug curative effect monitoring, in particular to wearable drug curative effect monitoring equipment which comprises a wearable garment, two arm sleeves are fixedly connected to the upper portion of the wearable garment, a micro monitoring controller is arranged on one side of the left arm sleeve, and a monitoring operation box is connected to the upper surface of the micro monitoring controller. A blood collecting unit is arranged on the right side of the interior of the monitoring operation box and comprises a linkage box movably arranged in the monitoring operation box, a sealing hole plate is arranged on one side of the linkage box, a sealing piece is slidably arranged on the upper portion of the sealing hole plate in an inserted mode, and a collecting hopper is fixedly connected to the right side of the linkage box; two extraction suction pipes are arranged at the upper end of the collection hopper, so that when a patient goes out, the effect of the medicine in the body can be regulated, controlled and monitored, the overall medicine curative effect is judged in cooperation with comprehensive monitoring of saliva and urine, and the overall medicine curative effect monitoring effect and efficiency are guaranteed.

Description

Technical Field

[0001] The present invention relates to the technical field of drug efficacy monitoring, in particular to a wearable drug efficacy monitoring device. Background Art

[0002] Therapeutic drug monitoring (TDM) is a branch of clinical medicine that has developed rapidly in recent years and is an important part of clinical pharmacology. Therapeutic drug monitoring refers to the process of collecting blood (or urine, saliva) from patients at regular intervals to measure the drug concentration while observing the drug efficacy during clinical drug treatment. Based on the individual conditions of the patients, the basic theories of pharmacokinetics and pharmacodynamics are used as guidance, and with the help of advanced analytical technology and electronic computer technology, the treatment plan is individualized to achieve satisfactory efficacy and avoid the occurrence of toxic reactions.

[0003] At present, the existing wearable drug efficacy monitoring equipment has the following deficiencies in use: First, in patient efficacy monitoring, the usual monitoring implementation steps can be divided into: application, sampling, measurement, data processing and result interpretation, and the process is relatively long. For drugs with a small efficacy range and a short half-life, samples should be collected at peak and trough values. The peak blood drug concentration is generally 15-30 minutes after intravenous administration, 1-2 hours after intramuscular injection, and 1.5 hours after oral administration. Therefore, for elderly patients with impaired liver and kidney function and patients with underlying liver and kidney diseases, waiting for sampling, then sending it for testing, and waiting for the test data information to come out, etc., a series of operations are extremely inconvenient for patients, and even cause damage to the body, which greatly reduces the quality of monitoring efficacy. In addition, the monitoring operation time is too long, which is inconvenient for patients to go out for activities, which invisibly increases the two-way burden of doctors and patients, and reduces the overall efficiency and effectiveness of drug efficacy monitoring.

[0004] Therefore, those skilled in the art provide a wearable drug efficacy monitoring device to solve the problems raised in the above background technology. Summary of the invention

[0005] In view of the deficiencies of the prior art, the present invention provides a wearable drug efficacy monitoring device, which solves the following problems: In the use of the existing wearable drug efficacy monitoring device, firstly, in the patient efficacy monitoring, the usual monitoring implementation steps can be divided into: application, sampling, determination, data processing and result interpretation, and the process is relatively long. Therefore, for drugs with a small efficacy range and a short half-life, samples should be collected at the peak and valley values. The peak of blood drug concentration is generally 15-30 minutes after intravenous administration, 1-2 hours after intramuscular injection, and 1.5 hours after oral administration. Therefore, for elderly patients with hepatic and renal insufficiency and patients with basic hepatic and renal function diseases, waiting for sampling, then sending it for testing, and taking it after the test data information comes out, etc., the patients are extremely inconvenient and even cause damage to the body, which greatly reduces the quality of monitoring efficacy. In addition, the monitoring operation time is too long, which is inconvenient for patients to go out and activities, and invisibly increases the two-way burden of doctors and patients.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0007] The technical solution adopted by the present invention to solve its technical problem is: a wearable drug efficacy monitoring device, including a wearable suit, wherein two arm sleeves are fixedly connected to the upper part of the wearable suit, a micro-monitoring controller is arranged on one side of the left arm sleeve, a monitoring operation box is connected to the upper surface of the micro-monitoring controller, a blood collection unit is arranged on the right side inside the monitoring operation box, the blood collection unit includes a linkage box movably arranged inside the monitoring operation box, a sealing orifice plate is arranged on one side of the linkage box, a sealing sheet is inserted and slidably arranged on the upper part of the sealing orifice plate, a collection bucket is fixedly connected to the right side of the linkage box, two extraction straws are arranged on the upper end of the collection bucket, a plurality of placement grooves are opened on the upper end of the linkage box, and the inner sides of the plurality of placement grooves are A collection container is provided, a plurality of circular holes corresponding to the sealing orifice plate are opened on the right side of the placement groove, the extraction straw is interspersed with the linkage box and used in conjunction with the sealing orifice plate, a saliva collection unit is provided on the right side inside the monitoring operation box, the saliva collection unit includes an elastic sleeve fixedly connected to one side of the linkage box, a flow guide cover is provided on the inner side of the elastic sleeve, the flow guide cover is interspersed with the linkage box and used in conjunction with the sealing orifice plate, a regulation operation unit is provided inside the monitoring operation box, an adhesive sheet is provided on the outer surface of the wearable suit, a blood pressure detection unit is provided on the outer surface of the arm cuff on the left side, tightening belts are provided on both sides of the wearable suit, a urine collection unit is provided on the outer surface of the adhesive sheet, and the interior of the monitoring operation box is fixedly connected with The dividing plate is provided with two detection cylinders at the upper end, and the upper ends of the two detection cylinders are connected to the first collecting tubes, a plurality of placement grooves are opened on one side of the linkage box, and the inner sides of the plurality of placement grooves are provided with collecting containers, and the upper ends of the plurality of placement grooves are jointly installed with a snap-fit ​​cover, and the two first collecting tubes are connected with the corresponding two collecting containers through the placement grooves, and the inner sides of the two detection cylinders are rotatably connected with threaded rotating rods, and the outer surfaces of the threaded rotating rods are fixedly connected with a plurality of auxiliary rods, and the outer surfaces of the threaded rotating rods are fixedly covered with a net cylinder, and the outer surface of the net cylinder is fixedly covered with a sealing piston ring that is slidably arranged with the detection cylinder, and the two threaded rotating rods pass through the detection cylinder and extend to the outside and are jointly covered with a pulley disk, and the monitoring operation A micro motor is arranged inside the operating box, and the output shaft of the micro motor is fixedly connected to one of the threaded rotating rods. A plurality of rotating seats are rotatably connected to the inner bottom end of the monitoring operating box, and the outer surfaces of the plurality of rotating seats are fixedly covered with balancing blocks, wherein the upper surfaces of two rotating seats are arranged with blood storage containers, and the upper surfaces of the other two rotating seats are arranged with saliva storage containers, and one side of the plurality of saliva storage containers and the blood storage container is arranged with a small pump, wherein one side of two of the small pumps is connected to a third collecting tube, and the two third collecting tubes pass through the diverter and enter the interior of the detection cylinder to be connected with the net cylinder, and one side of the other two small pumps is connected to a second collecting tube, and the two second collecting tubes pass through the diverter to be connected with two of the placement slots,A diverter is provided on one side of the two saliva storage containers, an empty slot is interspersed on one side of the monitoring operation box, two test strips corresponding to the diverter are provided inside the empty slot, and a magnetic cover plate is rotatably connected to the upper end of the monitoring operation box, and a display is provided on the upper end of the magnetic cover plate.

[0008] Preferably, a needle cover is provided on the upper surface of the linkage box, and a needle is provided inside the needle cover.

[0009] Preferably, a cleaning and disinfecting device for use with the air guide cover is provided on the right side of the interior of the monitoring operation box.

[0010] Preferably, the control operation unit includes an arc-shaped adjustment roller arranged inside a monitoring operation box, and the inner side walls of the monitoring operation box are fixedly connected with positioning grooves, and a limiting groove is fixedly connected between the two positioning grooves, and a guide bridge is fixedly connected to one side of the two limiting grooves, and a resistance wheel is rollingly installed on the inner side of the positioning groove, and the inner wall of the positioning groove is provided with two groups of rubber bumps used in conjunction with the resistance wheel.

[0011] Preferably, the two resistance wheels are commonly connected with a rotating shaft, and guide blocks used in conjunction with the guide bridge are fixedly mounted on both sides of the rotating shaft, and an arc-shaped adjusting roller is fixedly mounted on the outer surface of the rotating shaft, and the outer arc surface of the arc-shaped adjusting roller is provided with a plurality of teeth.

[0012] Preferably, a plurality of fixed rods are transversely installed inside the monitoring operation box, and the outer surfaces of the plurality of fixed rods are slidably sleeved with ring sleeves, and connecting plates are fixedly connected between the plurality of ring sleeves. A micro push rod is arranged inside the monitoring operation box, and the protruding end of the micro push rod is fixedly connected to the middle ring sleeve, and the upper surfaces of the plurality of ring sleeves are commonly connected with a linkage tooth plate, which is meshed with the teeth, and two baffles are arranged on one side of the linkage tooth plate.

[0013] Preferably, the blood pressure detection unit comprises an arm band sleeved on the outer surface of the arm cuff, one side of the arm band is connected to a catheter, and the catheter is connected to a micro monitoring controller.

[0014] Preferably, the urine collection unit includes a urine collection bag arranged on the outer surface of the adhesive sheet, two buckles are fixedly connected to the lower surface of the urine collection bag, extension rod frames are interspersed on both sides of the adhesive sheet, the buckles are fixedly connected to the extension rod frames, and a collection bucket is provided on one side of the urine collection bag.

[0015] Preferably, two thermostats are installed on the right side of the interior of the monitoring operation box, and the thermostats are arranged horizontally.

[0016] Preferably, two cushion blocks are provided inside the monitoring operation box, and the cushion blocks are used in conjunction with the extraction straw.

[0017] Beneficial effects of the present invention:

[0018] 1. A wearable drug efficacy monitoring device described in the present invention drives the blood collection unit and the saliva collection unit to move to a predetermined position through the operation of the control operation unit in the device. First, the needle cover is opened to expose the needle, and the needle is wiped with alcohol for disinfection with a cotton swab. Then, the finger is pressed against the needle to wipe the first blood and squeeze out new blood. The extraction straw is pressed back and forth to inhale the squeezed blood. After the corresponding sealing sheet is pulled open, the blood flows into the corresponding collection container for collection. The mouth is aligned with one side of the collection bucket, and the saliva is gathered at the bottom of the mouth. It is spit into the collection bucket every 60 seconds. Generally, it is collected for 10 minutes. The saliva flows smoothly into the corresponding placement groove along the inner wall of the collection bucket. When blood and saliva are collected, the sealing sheet is closed after the collection is completed. The sample collected when the arm is shaken is merged with the internal storage liquid, which is conducive to the regulation and monitoring of the effect of the drug in the body through this device, and the blood and saliva are sampled regularly, which is convenient for the patient to monitor when going out and timely understand whether the drug efficacy has achieved the expected effect.

[0019] 2. A wearable drug efficacy monitoring device described in the present invention rotates a threaded rotating rod in a detection tube, thereby driving the mesh tube to reciprocate along the thread groove of the threaded rotating rod and driving the sealing piston ring to slide in the detection tube. The mesh tube and the sealing piston ring form a piston, and a negative pressure is formed inside the detection tube during the downward process. The collected blood sample is sucked in through the first collection tube, and after the detection tube is filled, the blood will generate resistance under the rotation of the auxiliary rod, and this resistance can be used to calculate the blood viscosity and display it on the display. Then, after the small pump is turned on, the blood is sucked in through the first collection tube. The three collecting tubes absorb the blood in the test tube. The blood first enters the mesh tube and then is drawn into the blood storage container for collection. The other two small pumps draw the saliva sample in the corresponding placement slot through the second collecting tube into the saliva storage container for collection and weighing. A few drops of urine are dripped out through the diverter onto the test paper for testing. The test data is displayed on the monitor, which is conducive to monitoring the fluctuation of blood drug concentration after sampling, avoiding the occurrence of ineffectiveness or toxic side effects, and coordinating with the comprehensive monitoring of saliva and urine to determine the overall drug efficacy, thereby ensuring the overall drug efficacy monitoring effect and efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0021] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present invention;

[0022] Figure 2 For the present invention Figure 1 Schematic diagram of the cross-sectional structure of the monitoring operation box;

[0023] Figure 3 For the present invention Figure 2 Schematic diagram of the component structure on the center split board;

[0024] Figure 4 For the present invention Figure 3 Schematic diagram of the multi-component enlarged structure;

[0025] Figure 5 For the present invention Figure 4 Schematic diagram of the structure from top view;

[0026] Figure 6 For the present invention Figure 5 Schematic diagram of the structure of the saliva collection unit and the blood collection unit;

[0027] Figure 7 For the present invention Figure 3 Schematic diagram of the structure at A in the middle;

[0028] Figure 8 For the present invention Figure 1 A schematic diagram of the enlarged cross-sectional structure of the middle detection tube;

[0029] Fig. 9 For the present invention Figure 1 Schematic diagram of the mid-length clothing structure;

[0030] Fig.10 For the present invention Fig. 9 Schematic diagram of the enlarged structure of the urine collection bag.

[0031] In the figure: 1. monitoring operation box; 2. wearable clothing; 3. arm sleeve; 4. arm band; 551. blood collection unit; 552. saliva collection unit; 553. control operation unit; 554. blood pressure detection unit; 555. urine collection unit; 6. micro monitoring controller; 7. catheter; 8. tightening belt; 9. urine collection bag; 10. adhesive sheet; 11. buckle; 12. extension rod rack; 13. magnetic cover plate; 14. display; 15. arc adjustment roller; 16. linkage gear plate; 17. baffle; 18. fixed rod; 19. ring sleeve; 20. micro push rod; 21. needle cover; 22. snap cover; 23. detection cylinder; 24. first collection tube; 25. small pump; 26. extraction straw; 27. pad; 28. thermostat; 29 , empty slot; 30, test paper; 31, saliva storage container; 32, second collection tube; 33, blood storage container; 34, third collection tube; 35, swivel seat; 36, balance block; 37, rotating shaft; 38, guide block; 39, resistance wheel; 40, guide bridge; 41, positioning slot; 42, teeth; 43, elastic sleeve; 44, guide cover; 45, placement slot; 46, collection container; 47, linkage box; 48, connecting plate; 49, needle; 50, limit slot; 56, sealing hole plate; 57, sealing sheet; 58, threaded rotating rod; 59, auxiliary rod; 60, mesh cylinder; 61, sealing piston ring; 62, pulley; 63, micro motor; 64, collection bucket; 65, diverter; 66, cleaning and disinfection device; 67, dividing plate. DETAILED DESCRIPTION

[0032] The embodiment of the present invention provides a wearable drug efficacy monitoring device, which solves the following problems: In the use of existing wearable drug efficacy monitoring devices, firstly, in the patient efficacy monitoring, the usual monitoring implementation steps can be divided into: application, sampling, determination, data processing and result interpretation, and the process is relatively long. Therefore, for drugs with a small efficacy range and a short half-life, samples should be collected at the peak and valley values. The peak of blood drug concentration is generally 15-30 minutes after intravenous medication, 1-2 hours after intramuscular injection, and 1.5 hours after oral medication. Therefore, for elderly patients with hepatic and renal insufficiency and patients with basic hepatic and renal function diseases, waiting for sampling, then sending it for testing, and taking it after the test data information comes out, etc., the patients are extremely inconvenient and even cause damage to the body, which greatly reduces the quality of monitoring efficacy. In addition, the monitoring operation time is too long, which is inconvenient for patients to go out and activities, and invisibly increases the two-way burden of doctors and patients.

[0033] In order to better understand the above technical solution, the above technical solution will be described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0034] like Figure 1-Figure 10As shown, a wearable drug efficacy monitoring device of the present invention comprises a wearable garment 2, two arm sleeves 3 are fixedly connected to the upper part of the wearable garment 2, a micro monitoring controller 6 is arranged on one side of the left arm sleeve 3, a monitoring operation box 1 is connected to the upper surface of the micro monitoring controller 6, a blood collection unit 551 is arranged on the right side inside the monitoring operation box 1, and the blood collection unit 551 comprises a linkage box 47 movably arranged inside the monitoring operation box 1, a sealing orifice plate 56 is arranged on one side of the linkage box 47, a sealing sheet 57 is inserted and slidably arranged on the upper part of the sealing orifice plate 56, a collecting bucket 64 is fixedly connected to the right side of the linkage box 47, two extraction straws 26 are arranged on the upper end of the collecting bucket 64, a plurality of placement slots 45 are opened on the upper end of the linkage box 47, and a plurality of placement slots 45 are arranged on the upper end of the linkage box 47. A collecting container 46 is provided on the inner side of the placement groove 45, and a plurality of circular holes corresponding to the sealing orifice plate 56 are opened on the right side of the placement groove 45. The extraction straw 26 is interspersed with the linkage box 47 and used in conjunction with the sealing orifice plate 56. A saliva collection unit 552 is provided on the right side of the interior of the monitoring operation box 1. The saliva collection unit 552 includes an elastic sleeve 43 fixedly connected to one side of the linkage box 47, and a flow guide cover 44 is provided on the inner side of the elastic sleeve 43. The flow guide cover 44 is interspersed with the linkage box 47 and used in conjunction with the sealing orifice plate 56. A regulating operation unit 553 is provided inside the monitoring operation box 1, an adhesive sheet 10 is provided on the outer surface of the wearable suit 2, a blood pressure detection unit 554 is provided on the outer surface of the left arm sleeve 3, and both sides of the wearable suit 2 are provided with Tightening belt 8, the outer surface of adhesive sheet 10 is provided with urine collection unit 555, the interior of monitoring operation box 1 is fixedly connected with dividing plate 67, the upper end of dividing plate 67 is provided with two detection cylinders 23, the upper ends of two detection cylinders 23 are connected with first collecting tubes 24, one side of linkage box 47 is provided with a plurality of placement grooves 45, the inner sides of a plurality of placement grooves 45 are provided with collecting containers 46, the upper ends of a plurality of placement grooves 45 are jointly installed with snap-fitting covers 22, the two first collecting tubes 24 are connected with the corresponding two collecting containers 46 through the placement grooves 45, the inner sides of two detection cylinders 23 are rotatably connected with threaded rotating rods 58, the outer surface of threaded rotating rods 58 is fixedly connected with a plurality of auxiliary rods 59, the outer surface of threaded rotating rods 58 is fixedly sleeved with The net cylinder 60 has a sealing piston ring 61 fixedly mounted on its outer surface and slidingly arranged with the detection cylinder 23. Two threaded rotating rods 58 pass through the detection cylinder 23 and extend to the outside and are jointly mounted with a pulley 62. A micro motor 63 is arranged inside the monitoring operation box 1, and the output shaft of the micro motor 63 is fixedly connected to one of the threaded rotating rods 58. A plurality of rotating seats 35 are rotatably connected to the bottom end of the inner part of the monitoring operation box 1, and a balance block 36 is fixedly mounted on the outer surfaces of the plurality of rotating seats 35. The upper surfaces of two of the rotating seats 35 are respectively provided with blood storage containers 33, and the upper surfaces of the other two rotating seats 35 are respectively provided with saliva storage containers 31. A small pump 25 is arranged on one side of the plurality of saliva storage containers 31 and the blood storage container 33.One side of the two small pumps 25 is connected to the third collecting tube 34, and the two third collecting tubes 34 pass through the diverter 65 and enter the interior of the detection tube 23 and communicate with the net tube 60. One side of the other two small pumps 25 is connected to the second collecting tube 32, and the two second collecting tubes 32 pass through the diverter 65 and communicate with two of the placement slots 45. One side of the two saliva storage containers 31 is provided with a diverter 65. One side of the monitoring operation box 1 is interspersed with an empty slot 29, and the inside of the empty slot 29 is connected to the detection tube 23. Two test strips 30 corresponding to the diverter 65 are arranged on the side, the upper end of the monitoring operation box 1 is rotatably connected with a magnetic cover plate 13, the upper end of the magnetic cover plate 13 is provided with a display 14, the upper surface of the linkage box 47 is provided with a needle cover 21, the interior of the needle cover 21 is provided with a needle 49, the right side of the interior of the monitoring operation box 1 is provided with a cleaning and disinfecting device 66 used in conjunction with the guide cover 44, and the interior of the monitoring operation box 1 is provided with two cushion blocks 27, and the cushion blocks 27 are used in conjunction with the extraction pipette 26.

[0035] According to the above technical solution, the needle cover 21 is opened to expose the needle 49, and the needle 49 is disinfected by wiping with alcohol using a cotton swab, and then the finger is pressed against the needle 49 to wipe the first blood, squeeze out new blood, and reciprocate to press the extraction straw 26 to suck in the squeezed blood. After the corresponding sealing sheet 57 is pulled open, the blood flows into the corresponding collection container 46 for collection. Before that, the corresponding saliva collection preparation work is done. After the blood collection is completed, the saliva can be collected. The mouth is aimed at one side of the guide cover 44, and the saliva is gathered at the bottom of the mouth. It is spit into the guide cover 44 every 60 seconds. Generally, 10 After 10 minutes, saliva flows smoothly into the corresponding placement groove 45 along the inner wall of the guide cover 44. When blood and saliva are collected, the sealing sheet 57 is closed after the collection is completed, and then the micro push rod 20 is restarted to operate in the same reverse operation as above, and the magnetic cover plate 13 is closed, and the monitoring operation box 1 becomes a sealed state. When the arm is shaken, the collected sample is merged with the internal storage liquid, and then the switch of the micro motor 63 is turned on from the micro monitoring controller 6, so that the threaded rotating rod 58 is driven to rotate in the detection cylinder 23, thereby driving the net cylinder 60 to reciprocate along the thread groove of the threaded rotating rod 58, and driving the sealing activity The plug ring 61 slides in the detection tube 23, and the mesh tube 60 and the sealing piston ring 61 form a piston. During the downward movement, a negative pressure is formed inside the detection tube 23, and the collected blood sample is sucked through the first collection tube 24. After the detection tube 23 is filled, the blood will generate resistance under the rotation of the auxiliary rod 59, and this resistance can be used to calculate the blood viscosity and display it on the display 14. Then, after the small pump 25 is turned on, the blood in the detection tube 23 is sucked through the third collection tube 34. The blood suction process is that it first enters the mesh tube 60 and is then drawn into the blood storage container 3. 3, and the other two small pumps 25 are used to draw the saliva samples in the corresponding placement grooves 45 through the second collection tube 32 into the saliva storage container 31 for collection and weighing, and a few drops of urine are dripped into the test paper 30 through the diverter 65 for detection. The detected data is displayed on the display 14, which is beneficial for the patient to use this device to regulate and monitor the effect of the drug in the body when going out, to timely understand whether the drug efficacy has achieved the expected effect, to facilitate the adjustment of the treatment plan, to monitor the fluctuation of blood drug concentration, to avoid the occurrence of ineffectiveness or toxic side effects, and to cooperate with saliva monitoring to determine the overall drug treatment.

[0036] A further technical solution is that the control operation unit 553 includes an arc-shaped adjustment roller 15 arranged inside the monitoring operation box 1, and the inner side walls of the monitoring operation box 1 are fixedly connected with positioning grooves 41, and the two positioning grooves 41 are fixedly connected with a limiting groove 50, and one side of the two limiting grooves 50 is fixedly connected with a guide bridge 40, and the inner side of the positioning groove 41 is rollingly installed with a resistance wheel 39, and the inner wall of the positioning groove 41 is provided with two groups of rubber protrusions used in conjunction with the resistance wheel 39, and the two resistance wheels 39 are commonly connected with a rotating shaft 37, and both sides of the rotating shaft 37 are fixedly sleeved with guide blocks 38 used in conjunction with the guide bridge 40 The outer surface of the rotating shaft 37 is fixedly sleeved with an arc-shaped adjusting roller 15, and the outer arc surface of the arc-shaped adjusting roller 15 is provided with a plurality of teeth 42. A plurality of fixed rods 18 are horizontally installed inside the monitoring operation box 1, and the outer surfaces of the plurality of fixed rods 18 are slidably sleeved with ring sleeves 19, and a connecting plate 48 is fixedly connected between the plurality of ring sleeves 19. A micro push rod 20 is arranged inside the monitoring operation box 1, and the protruding end of the micro push rod 20 is fixedly connected to the middle ring sleeve 19. The upper surfaces of the plurality of ring sleeves 19 are commonly connected with a linkage tooth plate 16, which is meshed with the teeth 42, and two baffles 17 are arranged on one side of the linkage tooth plate 16.

[0037] According to the above technical solution, the patient turns on the switch of the micro push rod 20 through the micro monitoring controller 6, and the micro push rod 20 drives the connecting plate 48 to move in parallel, so that the multiple ring sleeves 19 are driven to slide on the fixed rod 18, and further drives the linkage tooth plate 16 to move in parallel and mesh with the teeth 42, drives the arc-shaped adjustment roller 15 to rotate and the rear shaft 37 to follow the rotation, thereby driving the guide block 38 to rotate along the guide bridge 40, and drives the resistance wheel 39 to rotate and contact with the rubber protrusion. When the linkage tooth plate 16 moves to the predetermined position, it drives the baffle 17 to contact with the arc-shaped adjustment roller 15. At the same time, the directional rotation of the arc-shaped adjusting roller 15 is promoted. When the guide block 38 rotates to a horizontal state, it enters the inner side of the limiting groove 50 and rotates and moves, thereby turning the arc-shaped adjusting roller 15 over. In this process, the linkage box 47 is driven to move, so that the elastic sleeve 43 and the collecting bucket 64 are driven to move. When the collecting bucket 64 moves, the extraction straw 26 is driven to move, so that it is separated from the cushion block 27. Further, the blood collection unit 551 and the saliva collection unit 552 move to the predetermined position, which is conducive to the rapid adjustment of the monitoring equipment, convenient for collecting and testing samples, and improves the monitoring effect.

[0038] A further technical solution is that the blood pressure detection unit 554 includes an arm band 4 mounted on the outer surface of the arm cuff 3, and a catheter 7 is connected to one side of the arm band 4, and the catheter 7 is connected to the micro monitoring controller 6. The urine collection unit 555 includes a urine collection bag 9 arranged on the outer surface of the adhesive sheet 10, and two buckles 11 are fixedly connected to the lower surface of the urine collection bag 9. Extension rod racks 12 are interspersed on both sides of the adhesive sheet 10, and the buckles 11 are fixedly connected to the extension rod racks 12. A collection bucket 64 is arranged on one side of the urine collection bag 9, and two thermostats 28 are installed on the right side of the interior of the monitoring operation box 1, and the thermostat 28 is arranged horizontally.

[0039] According to the above technical solution, the test paper 30 can be extracted and replaced through the empty slot 29, and the extraction straw 26 can also be disassembled and replaced after use. After the test, the test time, number of times and other data are recorded, and the urine collection bag 9 is peeled off from the adhesive sheet 10 and pressed down, driving the buckle 11 and the rear extension rod frame 12 to slide out of the adhesive sheet 10, so that the urine collection bag 9 is adjusted to the urine collection position, and the collection bucket 64 is taken out for operation. After the test, the arm band 4 can be controlled to be propped up through the micro-monitoring controller 6 to test the patient's blood pressure. The data is analyzed and transmitted to the display 14 through the catheter 7 after being collected by the micro-monitoring controller 6. After all the collection is completed, the thermostat 28 is turned on, and the sample or test data is submitted to the hospital at the specified time, which is conducive to the use and replacement of each detection component, convenient for sample preservation, and improves the overall monitoring equipment effect.

[0040] The embodiment of the present invention also provides a wearable drug efficacy monitoring device, the specific working principle of which includes the following steps:

[0041] Before using this device, by wearing the monitoring device on the body, after taking specific medicines, the patient can extract blood, saliva and urine samples by himself according to the time arranged by the doctor. This device can extract samples by itself and then do basic tests, or it can extract complete samples and submit the collected samples in a unified manner. Then, when in use, when the predetermined monitoring time is reached, the patient turns on the switch of the micro push rod 20 from the micro monitoring controller 6, and the micro push rod 20 drives the connecting plate 48 to move in parallel, so that multiple ring sleeves 19 are driven to slide on the fixed rod 18, and further drives the linkage tooth plate 16 to move in parallel and mesh with the teeth 42, drives the arc-shaped adjustment roller 15 to rotate, and the rear shaft 37 follows the rotation, thereby driving the guide block 38 to rotate along the guide bridge 40, and drives the resistance wheel 39 rotates and contacts with the rubber protrusion. When the linkage tooth plate 16 moves to the predetermined position, it drives the baffle plate 17 to contact with the arc-shaped adjustment roller 15, and jointly promotes the directional rotation of the arc-shaped adjustment roller 15. When the guide block 38 rotates to a horizontal state, it enters the inner side of the limit groove 50 and rotates and moves, thereby turning the arc-shaped adjustment roller 15 over. In this process, the linkage box 47 is driven to move, so that the elastic sleeve 43 and the collection bucket 64 are driven to move. When the collection bucket 64 moves, the extraction straw 26 is driven to move, so that it is separated from the cushion block 27. Further, the blood collection unit 551 and the saliva collection unit 552 move to the predetermined position, first operate to open the needle cover 21 to expose the needle 49, wipe it with alcohol for disinfection with a cotton swab, and then contact the finger with the needle 49 to wipe the first blood and squeeze it. The new blood is drawn out, and the extraction straw 26 is pressed back and forth to inhale the squeezed blood. After the corresponding sealing piece 57 is pulled open, the blood flows into the corresponding collection container 46 for collection. The corresponding saliva collection preparations are done before, and the saliva collection can continue after the blood collection is completed. The mouth is aimed at one side of the guide cover 44, and the saliva gathers at the bottom of the mouth. It is spit into the guide cover 44 every 60 seconds. Generally, it is collected for 10 minutes. The saliva flows smoothly into the corresponding placement groove 45 along the inner wall of the guide cover 44. When the blood and saliva are collected, the sealing piece 57 is closed after the collection is completed, and then the micro push rod 20 is restarted to operate the same operation as above and reversely reset. The magnetic cover plate 13 is closed, and the monitoring operation box 1 becomes a sealed state. When the arm is shaken, the sample collected is in contact with the inner The storage liquid in the detection tube 23 is merged, and then the switch of the micro motor 63 is turned on from the micro monitoring controller 6, so that the threaded rotating rod 58 is driven to rotate in the detection tube 23, thereby driving the mesh tube 60 to reciprocate along the thread groove of the threaded rotating rod 58, and driving the sealing piston ring 61 to slide in the detection tube 23. The mesh tube 60 and the sealing piston ring 61 form a piston. During the downward process, a negative pressure is formed inside the detection tube 23, and the collected blood sample is sucked in through the first collecting tube 24. After filling the detection tube 23, the blood will generate resistance under the rotation of the auxiliary rod 59, and this resistance can be used to calculate the blood viscosity and display it on the display 14. Then, after the small pump 25 is turned on, the blood in the detection tube 23 is sucked in through the third collecting tube 34.The blood suction process is that it first enters the mesh tube 60, and then is extracted into the blood storage container 33 for collection. The saliva sample in the corresponding placement slot 45 is drawn into the saliva storage container 31 through the second collection tube 32 by the other two small pumps 25 for collection and weighing. A few drops of urine are dripped into the test paper 30 through the diverter 65 for detection. The detection data is displayed on the display 14. The test paper 30 can be extracted and replaced through the empty slot 29. The extraction straw 26 can also be disassembled and replaced after use. After the detection, the detection time, number of times and other data are recorded. Record it, peel off the urine collection bag 9 from the adhesive sheet 10 and press it down, drive the buckle 11 and the extension rod frame 12 to slide out in the adhesive sheet 10, so as to adjust the urine collection bag 9 to the urine collection position, take out the collection bucket 64 and operate it. After the test, the armband 4 can be controlled to stand up through the micro monitoring controller 6 to test the patient's blood pressure. The data is analyzed and transmitted to the display 14 through the catheter 7. After all the collection is completed, the thermostat 28 is turned on, and the sample or test data is submitted to the hospital at the specified time.

[0042] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of the present invention is defined by the attached claims and their equivalents.

Claims

1. A wearable drug efficacy monitoring device, characterized in that: The present invention comprises a wearable garment (2), wherein two arm sleeves (3) are fixedly connected to the upper part of the wearable garment (2), a micro monitoring controller (6) is arranged on one side of the left arm sleeve (3), the upper surface of the micro monitoring controller (6) is connected to a monitoring operation box (1), a blood collection unit (551) is arranged on the right side of the interior of the monitoring operation box (1), the blood collection unit (551) comprises a linkage box (47) movably arranged inside the monitoring operation box (1), a sealing orifice plate (56) is arranged on one side of the linkage box (47), a sealing sheet (57) is inserted and slidably arranged on the upper part of the sealing orifice plate (56), a collection bucket (64) is fixedly connected to the right side of the linkage box (47), and the collection bucket (64) is fixedly connected to the right side of the linkage box (47). 4) is provided with two extraction pipettes (26), the upper end of the linkage box (47) is provided with a plurality of placement grooves (45), the inner sides of the plurality of placement grooves (45) are provided with collection containers (46), the right side of the placement grooves (45) is provided with a plurality of circular holes corresponding to the sealing orifice plate (56), the extraction pipettes (26) and the linkage box (47) are interlaced and used in conjunction with the sealing orifice plate (56), the right side of the interior of the monitoring operation box (1) is provided with a saliva collection unit (552), the saliva collection unit (552) comprises an elastic sleeve (43) fixedly connected to one side of the linkage box (47), the inner side of the elastic sleeve (43) is provided with a flow guide cover (44), the flow guide cover (44) The monitoring operation box (1) is interspersed with the linkage box (47) and used in conjunction with the sealing hole plate (56). The interior of the monitoring operation box (1) is provided with a control operation unit (553). The outer surface of the wearable clothing (2) is provided with an adhesive sheet (10). The outer surface of the left arm sleeve (3) is provided with a blood pressure detection unit (554). Both sides of the wearable clothing (2) are provided with tightening belts (8). The outer surface of the adhesive sheet (10) is provided with a urine collection unit (555). The interior of the monitoring operation box (1) is fixedly connected with a split plate (67). The upper end of the split plate (67) is provided with two detection cylinders (23). The upper ends of the two detection cylinders (23) are connected to a first collection tube (24). The linkage box (4 7) is provided with a plurality of placement grooves (45) on one side, a collection container (46) is provided on the inner side of the plurality of placement grooves (45), a snap-fit ​​cover (22) is installed on the upper ends of the plurality of placement grooves (45), the two first collection tubes (24) pass through the placement grooves (45) and are connected with the corresponding two collection containers (46), the inner sides of the two detection cylinders (23) are rotatably connected with a threaded rotating rod (58), the outer surface of the threaded rotating rod (58) is fixedly connected with a plurality of auxiliary rods (59), the outer surface of the threaded rotating rod (58) is fixedly sleeved with a net cylinder (60), and the outer surface of the net cylinder (60) is fixedly sleeved with a sealing piston ring (61) slidably arranged with the detection cylinder (23),The two threaded rotating rods (58) both pass through the detection tube (23) and extend to the outside and are jointly covered with a pulley (62); a micro motor (63) is arranged inside the monitoring operation box (1); an output shaft of the micro motor (63) is fixedly connected to one of the threaded rotating rods (58); a plurality of rotating seats (35) are rotatably connected to the bottom end of the inside of the monitoring operation box (1); a balance block (36) is fixedly covered on the outer surfaces of the plurality of rotating seats (35); a blood storage container (33) is arranged on the upper surfaces of two of the rotating seats (35); a saliva storage container (31) is arranged on the upper surfaces of the other two rotating seats (35); a small pump (25) is arranged on one side of the plurality of saliva storage containers (31) and the blood storage container (33); one side of the two small pumps (25) The two sides of the monitoring operation box (1) are connected to a third collecting tube (34), and the two third collecting tubes (34) pass through the diverter (65) and enter the interior of the detection tube (23) to communicate with the net tube (60). The other two small pumps (25) are connected to a second collecting tube (32) on one side, and the two second collecting tubes (32) pass through the diverter (65) to communicate with two of the placement slots (45). The two saliva storage containers (31) are provided with a diverter (65) on one side. An empty slot (29) is interspersed on one side of the monitoring operation box (1), and two detection test strips (30) corresponding to the diverter (65) are provided on the inner side of the empty slot (29). The upper end of the monitoring operation box (1) is rotatably connected to a magnetic cover plate (13), and a display (14) is provided on the upper end of the magnetic cover plate (13).

2. A wearable drug efficacy monitoring device according to claim 1, characterized in that: The upper surface of the linkage box (47) is provided with a needle cover (21), and a needle (49) is provided inside the needle cover (21).

3. A wearable drug efficacy monitoring device according to claim 1, characterized in that: A cleaning and disinfecting device (66) for use in conjunction with the air guide cover (44) is arranged on the right side of the interior of the monitoring operation box (1).

4. A wearable drug efficacy monitoring device according to claim 1, characterized in that: The regulating and controlling operation unit (553) comprises an arc-shaped regulating roller (15) arranged inside the monitoring and operating box (1); the inner side walls of the monitoring and operating box (1) are fixedly connected with positioning grooves (41); a limiting groove (50) is fixedly connected between the two positioning grooves (41); one side of the two limiting grooves (50) is fixedly connected with a guide bridge (40); a resistance wheel (39) is rollingly mounted inside the positioning groove (41); and the inner wall of the positioning groove (41) is provided with two groups of rubber protrusions used in conjunction with the resistance wheel (39).

5. A wearable drug efficacy monitoring device according to claim 4, characterized in that: A rotating shaft (37) is commonly connected between the two resistance wheels (39), and guide blocks (38) used in conjunction with a guide bridge (40) are fixedly mounted on both sides of the rotating shaft (37). An arc-shaped adjusting roller (15) is fixedly mounted on the outer surface of the rotating shaft (37), and a plurality of teeth (42) are arranged on the outer arc surface of the arc-shaped adjusting roller (15).

6. A wearable drug efficacy monitoring device according to claim 5, characterized in that: A plurality of fixed rods (18) are transversely installed inside the monitoring operation box (1), and the outer surfaces of the plurality of fixed rods (18) are slidably sleeved with ring sleeves (19), and a connecting plate (48) is fixedly connected between the plurality of ring sleeves (19). A micro push rod (20) is arranged inside the monitoring operation box (1), and the protruding end of the micro push rod (20) is fixedly connected to the middle ring sleeve (19), and the upper surfaces of the plurality of ring sleeves (19) are commonly connected to a linkage tooth plate (16), and the linkage tooth plate (16) is meshed with the teeth (42), and two baffles (17) are arranged on one side of the linkage tooth plate (16).

7. A wearable drug efficacy monitoring device according to claim 1, characterized in that: The blood pressure detection unit (554) comprises an armband (4) sleeved on the outer surface of an arm cuff (3), one side of the armband (4) is connected to a catheter (7), and the catheter (7) is connected to a micro monitoring controller (6).

8. A wearable drug efficacy monitoring device according to claim 1, characterized in that: The urine collection unit (555) comprises a urine collection bag (9) arranged on the outer surface of an adhesive sheet (10), two buckles (11) are fixedly connected to the lower surface of the urine collection bag (9), extension rod frames (12) are interspersed on both sides of the adhesive sheet (10), the buckles (11) are fixedly connected to the extension rod frames (12), and a collection bucket (64) is arranged on one side of the urine collection bag (9).

9. A wearable drug efficacy monitoring device according to claim 1, characterized in that: Two thermostats (28) are installed on the right side of the interior of the monitoring operation box (1), and the thermostats (28) are arranged horizontally.

10. A wearable drug efficacy monitoring device according to claim 1, characterized in that: Two cushion blocks (27) are arranged inside the monitoring operation box (1), and the cushion blocks (27) are used in conjunction with the extraction pipette (26).

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