Microcapsule preparation device capable of adjusting electric field

Abstract

The embodiment of the invention provides a microcapsule preparation device capable of adjusting an electric field, and relates to the field of microcapsule preparation. The microcapsule preparation device capable of adjusting the electric field comprises a base, a support arm, a movable arm, a positive electrode metal sheet, a negative electrode circular ring and a negative electrode metal sheet, the movable arm is in sliding connection with the support arm, the positive electrode metal sheet is arranged on the movable arm, a support structure is arranged on the upper surface of the base, the support arm is connected with the support structure, and the negative electrode circular ring is connected with the support structure; the positive electrode metal sheet is located on the upper side of the negative electrode circular ring, and the movable arm can drive the positive electrode metal sheet to be close to or away from the negative electrode circular ring; and the cathode metal sheet is arranged on the upper surface of the base. By introducing the design of the movable arm, the distance between the positive electrode metal sheet and the negative electrode circular ring is adjusted, so that the problem of inflexible adjustment of the electric field intensity caused by fixed electrode distance in the prior art is effectively solved.

Description

Technical Field

[0001] The invention relates to the field of microcapsule preparation, in particular to a microcapsule preparation device capable of adjusting the electric field. Background Art

[0002] Microencapsulation technology has shown broad application prospects in biomedical and pharmaceutical fields such as cell transplantation immune isolation, drug controlled release, and artificial organ construction. As a tool that can effectively isolate transplanted cells from the host immune system, microencapsulation technology provides an ideal solution to immune rejection. The successful application of this technology not only helps to improve the effectiveness of cell therapy, but also opens up new ways to treat various complex diseases. Therefore, microencapsulation technology has received widespread attention in recent years and is regarded as one of the important directions for the future development of medicine.

[0003] However, the existing technology still has certain limitations in terms of electric field regulation, mainly reflected in the difficulty in adjusting the electric field strength due to the fixed distance between electrodes. In order to increase the electric field strength, the voltage can only be increased. However, high voltage may cause a series of side effects, such as higher requirements for equipment and possible unnecessary thermal effects, resulting in damage to biological samples or other unintended effects. The development of a microcapsule preparation device that can adjust the electric field strength by controlling the distance between electrodes will overcome the above-mentioned defects of the existing technology, significantly reduce the required voltage, and avoid damage to equipment and biological samples. Summary of the invention

[0004] According to an embodiment of the present invention, a microcapsule preparation device with adjustable electric field is provided to solve the problems raised by the above background technology.

[0005] In a first aspect of the present invention, a microcapsule preparation device with adjustable electric field is provided.

[0006] The microcapsule preparation device with adjustable electric field comprises: a base, a support arm, a movable arm, a positive metal sheet, a negative electrode ring and a negative electrode metal sheet; the movable arm is slidably connected to the support arm, the positive electrode metal sheet is arranged on the movable arm, the upper surface of the base is provided with a supporting structure, the support arm is connected to the supporting structure, and the negative electrode ring is connected to the supporting structure; the positive electrode metal sheet is located on the upper side of the negative electrode ring, and the movable arm can drive the positive electrode metal sheet to approach or move away from the negative electrode ring; the negative electrode metal sheet is arranged on the upper surface of the base.

[0007] Preferably, a slide with a trapezoidal cross-section is provided on the support arm, the movable arm extends into the slide and is slidably connected to the slide; the microcapsule preparation device with adjustable electric field also includes a first adjustment component, the first adjustment component includes a fixed arm, an adjustment screw and a limit portion; the fixed arm is fixedly connected to the support arm, the adjustment screw passes through the fixed arm and is threadedly connected to the fixed arm, the adjustment screw passes through the movable arm and is rotatably connected to the movable arm, and the limit portion is connected to the lower end of the adjustment screw.

[0008] Preferably, a placement groove for placing a beaker is provided on the upper surface of the base, and the negative electrode metal sheet is arranged in the placement groove.

[0009] Preferably, a handle is provided at the upper end of the adjusting screw.

[0010] Preferably, the support structure includes a support column and a second adjustment component; the support column is fixedly connected to the upper surface of the base, and the second adjustment component is connected to the support column.

[0011] Preferably, the second adjustment component comprises: a connecting arm, a mounting ring and four driving components; the negative electrode ring is composed of four arc-shaped metal plates; the connecting arm is fixedly connected to the support column, one end of the connecting arm away from the support column is fixedly connected to the mounting ring, and the four arc-shaped metal plates are connected to the mounting ring through the driving component; The driving assembly includes a second motor, a wire wheel, a metal wire, a first guide column and a second spring. The second motor is fixedly mounted on the outer side of the mounting ring. The wire wheel is connected to the output end of the second motor. One end of the metal wire is fixedly connected to the wire wheel. The metal wire passes through the mounting ring and is slidably connected to the mounting ring. One end of the metal wire away from the wire wheel is connected to the second motor. The first guide column passes through the mounting ring and is slidably connected to the mounting ring. The first guide column is fixedly connected to the arc-shaped metal plate. The second spring is sleeved on the first guide column. One end of the second spring is connected to the mounting ring, and the other end of the second spring is in contact with the arc-shaped metal plate.

[0012] Preferably, a contact ring is sleeved on the metal wire, the contact ring is slidably connected to the metal wire, and the contact ring is connected to a joint via a conductor.

[0013] Preferably, the supporting structure also includes an adjusting platform, which includes: a slot body, a first moving block, a first lead screw, a first motor, a second moving block, a second lead screw, a third motor and a second guide column; the slot body is fixedly connected to the upper end of the support column, the first moving block is slidably installed in the movable slot of the slot body, the first lead screw passes through the slot body and is rotatably connected to the slot body, the first motor is connected to the first lead screw for driving the first lead screw to rotate, the first lead screw passes through the first moving block and is threadedly connected to the first moving block, the second guide column is fixedly connected to the first moving block, the second lead screw is rotatably connected to the first moving block, the third motor is connected to the second lead screw for driving the second lead screw to rotate, the second moving block is slidably connected to the second guide column, the second lead screw passes through the second moving block and is threadedly connected to the second moving block, and the second moving block is fixedly connected to the support arm.

[0014] Preferably, the movable arm includes a main body, a mounting block, two pins, two first springs and a mounting protrusion; the mounting protrusion is fixedly connected to the main body and is an integrated structure; a first semi-annular notch is provided on the mounting block, a second semi-annular notch is provided on the mounting protrusion, two spring grooves are provided in the mounting protrusion, two of the first springs are provided in the spring grooves, and two of the pins pass through the mounting block, the spring grooves and the first springs to connect the mounting block and the mounting protrusion; the first semi-annular notch and the second semi-annular notch form an annular notch for accommodating a needle; the two first springs provide the pin with elastic force in the direction close to the main body, and a limiting cap is provided at one end of the two pins away from the main body; a camera is installed on the lower surface of the main body.

[0015] Preferably, a contact surface is provided on the pin shaft, and the first spring contacts the contact surface; support parts matching the needle head are respectively provided in the first semi-annular notch and the second semi-annular notch, and the positive metal sheet is provided on the support parts.

[0016] One or more technical solutions provided in this application have at least the following technical effects or advantages: The present invention provides a microcapsule preparation device with adjustable electric field. By introducing the design of a movable arm, the distance between the positive electrode metal sheet and the negative electrode ring can be flexibly adjusted, thereby effectively overcoming the problem of inflexible electric field strength adjustment caused by the fixed electrode spacing in the prior art. By adjusting the distance between the positive electrode metal sheet and the negative electrode ring, the electric field strength can be precisely controlled without relying on high voltage, avoiding the side effects such as increased equipment complexity and unnecessary thermal effects caused by high voltage, thereby improving the safety of the device in biological sample processing and the repeatability of experimental results.

[0017] The movement of the positive metal sheet is linked to the segmented electric field negative electrode. First, the positive metal sheet maintains a fixed spacing above the electric field negative electrode and moves along a fan-shaped trajectory. Secondly, when a certain section of the segmented electric field negative electrode moves, the positive metal sheet still maintains a fixed spacing from the electric field negative electrode. The beneficial effect of this scheme is that due to the influence of the surface tension of the liquid in the beaker, the sodium alginate solution may not be able to calcify quickly, resulting in the accumulation of sodium alginate on the surface of the calcium chloride solution. This scheme adjusts the dripping position of sodium alginate by moving the needle and the segmented electric field negative electrode, which greatly reduces the occurrence of accumulation.

[0018] It should be understood that the contents described in the summary of the invention are not intended to limit the key or important features of the embodiments of the present invention, nor are they intended to limit the scope of the present invention. Other features of the present invention will become easily understood through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The above and other features, advantages and aspects of the embodiments of the present invention will become more apparent with reference to the following detailed description in conjunction with the accompanying drawings. In the accompanying drawings, the same or similar reference numerals represent the same or similar elements, wherein: Figure 1 A schematic diagram of the three-dimensional structure of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Figure 2 An exploded view of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Figure 3 A schematic structural diagram showing the connection between the support arm, the movable arm and the first adjustment component of the microcapsule preparation device with adjustable electric field according to an embodiment of the present invention; Figure 4 A schematic diagram of the three-dimensional structure of the base and the supporting structure of the microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown.

[0020] Figure 5 A schematic diagram of the three-dimensional structure of a second adjustment component of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown at a first viewing angle; Figure 6 A schematic diagram of the three-dimensional structure of a second adjusting component of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Figure 7 An exploded view of a movable arm of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Figure 8 A partial cross-sectional schematic diagram of a movable arm of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Fig. 9 A partial cross-sectional structural schematic diagram of a main body and a protrusion of an adjustable electric field according to an embodiment of the present invention is shown; Fig.10 An exploded view showing a movable arm and a needle of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention; Fig.11 A schematic diagram of a three-dimensional cross-sectional structure of a movable arm and a needle of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Fig.12 A schematic plan cross-sectional structure diagram of a movable arm and a needle of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown; Fig.13 A system block diagram of a microcapsule preparation device with adjustable electric field according to an embodiment of the present invention is shown.

[0021] Description of Reference Numerals 1-base, 11-slot, 2-support arm, 21-slide, 3-movable arm, 31-main body, 32-mounting block, 321-first semi-annular notch, 33-pin, 331-limiting cap, 332-contact surface, 34-first spring, 35-protrusion, 351-second semi-annular notch, 352-spring groove, 36-support part, 37-needle, 4-positive metal sheet, 5-negative ring, 51-arc metal plate, 6-negative metal sheet, 7-first adjustment component, 71-fixed arm, 72-adjusting screw, 73-limiting part, 74-handle, 8-beaker, 9- Support structure, 91-support column, 92-second adjusting assembly, 921-connecting arm, 922-mounting ring, 923-driving assembly, 9231-second motor, 9232-reel, 9233-metal wire, 9234-first guide column, 9235-second spring, 9236-contact ring, 9237-conductor, 9238-connector, 93-adjusting platform, 931-trough body, 932-first moving block, 933-first lead screw, 934-first motor, 935-second moving block, 936-second lead screw, 937-third motor, 938-second guide column. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] In addition, the term "and / or" in this article is only a description of the association relationship between the associated objects, indicating that there can be three relationships. For example, A and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. In addition, the character " / " in this article generally indicates that the associated objects before and after are in an "or" relationship.

[0024] like Figures 1 to 12 As shown, the microcapsule preparation device with adjustable electric field includes: a base 1, a support arm 2, a movable arm 3, a positive metal sheet 4, a negative electrode ring 5 and a negative electrode metal sheet 6; the movable arm 3 is slidably connected to the support arm 2, the positive electrode metal sheet 4 is arranged on the movable arm 3, the upper surface of the base 1 is provided with a supporting structure 9, the support arm 2 is connected to the supporting structure 9, and the negative electrode ring 5 is connected to the supporting structure 9; the positive electrode metal sheet 4 is located on the upper side of the negative electrode ring 5, and the movable arm 3 can drive the positive electrode metal sheet 4 to approach or move away from the negative electrode ring 5; the negative electrode metal sheet 6 is arranged on the upper surface of the base 1.

[0025] When in use, the positive metal sheet 4 is connected to the positive pole of the power source, and the negative ring 5 and the negative metal sheet 6 are connected to the negative pole of the power source to form a high voltage electric field. By adjusting the position of the movable arm 3, the movable arm 3 is moved along the vertical direction of the support arm 2, and the movable arm 3 drives the positive metal sheet 4 to move up and down, thereby adjusting the distance between the positive metal sheet 4 and the negative ring 5, and then achieving the purpose of adjusting the electric field strength.

[0026] In actual use, the needle 9 is mounted on the movable arm 3, and a conductive metal part 371 is provided on the needle 9, and the metal part 371 is connected to the positive metal sheet 4. The needle 9 is filled with a sodium alginate solution. Under the action of the high-voltage electric field formed between the positive metal sheet 4 and the negative ring 5, the sodium alginate solution forms a Taylor Cone at the needle tip, thereby generating charged sodium alginate droplets. While the Taylor cone is formed, the high-voltage electric field further affects the sodium alginate solution, causing it to eject fine droplets from the tip of the Taylor cone. These droplets are charged due to the action of the electric field. Since the charges on the surface of the droplets repel each other (Coulomb repulsion), a mutually repulsive force is generated between the droplets. At this time, the electric field force and the electrostatic repulsion act together, causing the originally larger droplets to split into multiple smaller and more uniform droplets. The charged droplets move in the direction of the electric field (downward) under the action of the electric field force. Since these droplets carry the same charge, there is Coulomb repulsion (electrostatic repulsion) between them, which keeps the droplets at a certain distance during movement and prevents them from agglomerating. This process ensures further dispersion of the droplets, making them evenly distributed in space. The electric field force not only pushes the droplets downward, but also guides the trajectory of the droplets, and the small droplets fall into the beaker 8 containing the calcium chloride solution through the negative electrode ring 5. When these charged droplets fall into the beaker containing the calcium chloride solution, the calcium ions (Ca²⁺) in the calcium chloride solution undergo an ion exchange reaction with the sodium ions (Na⁺) in the sodium alginate. This reaction results in the formation of calcium alginate (Ca-alginate), a gel that is insoluble in water. This reaction causes the surface of the droplets to solidify rapidly, forming stable microcapsules.

[0027] The negative electrode metal sheet 6 is used to attract the liquid droplets and reduce splashing when the liquid droplets fall into the beaker 8. In particular, if only the negative electrode ring 5 is provided, after the liquid droplets pass through the negative electrode ring 5, the electric field will exert an upward force on the liquid droplets, which may affect the falling trajectory of the liquid droplets and cause splashing when the liquid droplets enter the beaker 8. Therefore, the provision of the negative electrode metal sheet 6 helps to ensure that the liquid droplets fall into the beaker smoothly and reduce the occurrence of splashing.

[0028] The Taylor cone is a unique phenomenon caused by the electric field force acting on the liquid surface, and its formation indicates that the liquid is about to undergo electrospray; the positive electrode metal sheet 4, the negative electrode metal sheet 6 and the negative electrode ring 5 are all made of copper.

[0029] The microcapsule preparation device with adjustable electric field realizes flexible adjustment of the distance between the positive metal sheet 4 and the negative electrode ring 5 by introducing the design of the movable arm 3, thereby effectively overcoming the problem of inflexible adjustment of the electric field strength caused by the fixed electrode spacing in the prior art. By adjusting the distance between the positive metal sheet 4 and the negative electrode ring 5, the electric field strength can be precisely controlled without relying on high voltage, avoiding the side effects such as increased equipment complexity and unnecessary thermal effects caused by high voltage, thereby improving the safety of the device in biological sample processing and the repeatability of experimental results.

[0030] Specifically, a slide 21 with a trapezoidal cross-section is provided on the support arm 2, and the movable arm 3 extends into the slide 21 and is slidably connected to the slide 21; the microcapsule preparation device with adjustable electric field also includes a first adjustment component 7, and the first adjustment component 7 includes a fixed arm 71, an adjustment screw 72 and a limit portion 73; the fixed arm 71 is fixedly connected to the support arm 2, the adjustment screw 72 passes through the fixed arm 71 and is threadedly connected to the fixed arm 71, the adjustment screw 72 passes through the movable arm 3 and is rotatably connected to the movable arm 3, and the limit portion 73 is connected to the lower end of the adjustment screw 72.

[0031] By rotating the adjusting screw 72, the adjusting screw 72 can be lifted and lowered relative to the fixed arm 71. When the adjusting screw 72 moves upward, the limiter 73 drives the movable arm 3 to move upward; when the adjusting screw 72 moves downward, the adjusting screw 72 drives the movable arm 3 to move downward, thereby achieving precise adjustment of the height of the movable arm 3. As the movable arm 3 moves along the vertical direction of the support arm 2, the movable arm 3 will also drive the positive metal sheet 4 to move up and down accordingly, thereby achieving the adjustment of the distance between the positive metal sheet 4 and the negative electrode ring 5, and finally achieving the purpose of precise control of the electric field strength.

[0032] Specifically, the upper surface of the base 1 is provided with a placement groove 11 for stably placing the beaker 8, and the shape and size of the placement groove 11 match the beaker 8 to ensure that the beaker remains stable during operation. The negative electrode metal sheet 6 is fixedly installed at the bottom of the placement groove 11, directly below the beaker 8. This helps to ensure the precise positioning of the contact area between the negative electrode metal sheet 6 and the droplets, and can also reduce splashing and overflow when the droplets enter the beaker 8 by effectively guiding and collecting the charged droplets.

[0033] Specifically, a handle 74 is provided at the upper end of the adjusting screw 72. The setting of the handle 74 facilitates the rotation of the adjusting screw 72.

[0034] Specifically, the support structure 9 includes a support column 91 and a second adjustment component 92. The support column 91 is fixedly connected to the upper surface of the base 1, and the second adjustment component 92 is connected to the support column 91. The second adjustment component 92 includes a connecting arm 921, a mounting ring 922 and four driving components 923. The negative electrode ring 5 is composed of four arc-shaped metal plates 51. The connecting arm 921 is fixedly connected to the support column 91, and one end of the connecting arm 921 away from the support column 91 is fixedly connected to the mounting ring 922, and the four arc-shaped metal plates 51 are connected to the mounting ring 922 through the driving component 923.

[0035] The driving assembly 923 includes a second motor 9231, a wire wheel 9232, a metal wire 9233, a first guide post 9234 and a second spring 9235. The second motor 9231 is fixedly mounted on the outer side of the mounting ring 922, and the wire wheel 9232 is connected to the output end of the second motor 9231. One end of the metal wire 9233 is fixedly connected to the wire wheel 9232, passes through the mounting ring 922 and is slidably connected thereto, and one end of the metal wire 9233 away from the wire wheel 9232 is connected to the second motor 9231. The first guide post 9234 passes through the mounting ring 922 and is slidably connected thereto, and the first guide post 9234 is fixedly connected to the arc-shaped metal plate 51. The second spring 9235 is sleeved on the first guide post 9234, one end of which is connected to the mounting ring 922, and the other end of which is in contact with the arc-shaped metal plate 51.

[0036] like Fig.13 As shown, the microcapsule preparation device with adjustable electric field also includes a central controller, which is used to control four driving components 923 to drive the four arc-shaped metal plates 51 to move.

[0037] Furthermore, if Figure 1 , Figure 2 , Figure 5 and Figure 6 As shown, in the initial state, the second spring 9235 is in an extended state, and the four arc-shaped metal plates 51 are in contact with each other to form a circular ring (negative pole circular ring 5). When the electric field needs to be adjusted, the central controller controls the output end of the second motor 9231 to rotate, and the second motor 9231 drives the wire wheel 9232 to rotate, and the wire wheel 9232 winds the metal wire 9233, and the metal wire 9233 pulls the arc-shaped metal plate 51 in a direction away from the center of the mounting ring 922, and the second spring 9235 is compressed, thereby changing the shape of the negative pole circular ring 5, forming a segmented electric field negative pole, and realizing the adjustment of the electric field. Conversely, by controlling the second motor 9231 to drive the wire wheel 9232 to release the metal wire 9233, the arc-shaped metal plate 51 will return to the initial state with the help of the restoring force of the second spring 9235.

[0038] Specifically, a contact ring 9236 is sleeved on the metal wire 9233, and the contact ring 9236 is slidably connected to the metal wire 9233. The contact ring 9236 is connected to the connector 9238 through the conductor 9237, and the connector 9238 is used to connect the negative electrode of the power supply. The metal wire 9233 is connected to the negative electrode of the power supply through the conductor 9237 and the contact ring 9236. Among them, the contact ring 9236 is made of copper, thereby realizing the effective connection between the metal wire 9233 and the negative electrode of the power supply.

[0039] Specifically, the support structure 9 also includes an adjustment platform 93, which is composed of a slot body 931, a first moving block 932, a first lead screw 933, a first motor 934, a second moving block 935, a second lead screw 936, a third motor 937 and a second guide column 938. The slot body 931 is fixedly connected to the upper end of the support column 91, and the first moving block 932 is slidably installed in the movable slot of the slot body 931. The first lead screw 933 penetrates the slot body 931 and is rotatably connected to the slot body 931, and the first motor 934 is connected to the first lead screw 933 to drive it to rotate. The first lead screw 933 passes through the first moving block 932 and is threadedly connected to it. The second guide column 938 is fixedly connected to the first moving block 932, the second lead screw 936 is rotatably connected to the first moving block 932, and the third motor 937 is connected to the second lead screw 936 to drive it to rotate. The second moving block 935 is slidably connected to the second guide column 938 , the second lead screw 936 passes through the second moving block 935 and is threadedly connected thereto, and the second moving block 935 is fixedly connected to the support arm 2 .

[0040] The first motor 934 and the third motor 937 are controlled by the central controller respectively. The output end of the first motor 934 drives the first lead screw 933 to rotate, thereby pushing the first moving block 932 to slide in the movable groove of the groove body 931. The movement of the first moving block 932 drives the second moving block 935 to move through the second guide column 938, and the second moving block 935 drives the needle 37 to move through the support arm 2 and the movable arm 3 to adjust the first direction of the needle 37. The third motor 937 drives the second lead screw 936 to rotate, driving the second moving block 935 to move in the second direction, and the second moving block 935 also drives the needle 37 to move through the support arm 2 and the movable arm 3 to adjust the second direction of the needle 37. Among them, the first direction is perpendicular to the second direction, thereby adjusting the position of the needle 37 to prevent the accumulation of droplets in the beaker and avoid the accumulation of microcapsules.

[0041] The movement of the positive metal sheet 4 is linked with the segmented electric field negative electrode. First, the positive metal sheet 4 moves at a fixed spacing above the electric field negative electrode and runs along a fan-shaped trajectory. Secondly, when a certain section of the segmented electric field negative electrode moves, the positive metal sheet 4 still moves at a fixed spacing with the electric field negative electrode. The beneficial effect of this scheme is that, affected by the surface tension of the liquid in the beaker, the sodium alginate solution may not be able to calcify quickly, causing sodium alginate to accumulate on the surface of the calcium chloride solution. However, this scheme adjusts the dripping position of sodium alginate through the movement of the needle 37 and the segmented electric field negative electrode, which greatly reduces the occurrence of accumulation.

[0042] Specifically, the movable arm 3 includes a main body 31, a mounting block 32, two pins 33, two first springs 34 and a mounting protrusion 35; the mounting protrusion 35 is fixedly connected to the main body 31 and is an integrated structure; a first semi-annular notch 321 is provided on the mounting block 32, a second semi-annular notch 351 is provided on the mounting protrusion 35, two spring grooves 352 are provided in the mounting protrusion 35, two first springs 34 are provided in the spring grooves 352, and two pins 33 pass through the mounting block 32, the spring grooves 352 and the first springs 34 to connect the mounting block 32 and the mounting protrusion 35; the first semi-annular notch 321 and the second semi-annular notch 351 form an annular notch for accommodating a needle 37; the two first springs 34 provide elastic force for the pin 33 in the direction close to the main body 31, and a limiting cap 331 is provided at one end of the two pins 33 away from the main body 31; a camera 38 is installed on the lower surface of the main body 31.

[0043] Two springs 34 are installed in the spring slots 352, and the mounting block 32 is connected to the mounting protrusion 35 through two pins 33. The pin 33 passes through the mounting block 32, the spring slots 352 and the spring 34, and a limit cap 331 is provided at one end thereof away from the main body 31. The function of the limit cap 331 is to limit the moving distance of the pin 33 and provide elastic force for the mounting block 32 to approach the mounting protrusion 35.

[0044] Furthermore, Fig.13 As shown, the microcapsule preparation device with adjustable electric field also includes a video collector and a digital processing unit. The video collector is connected to a camera 38, and the camera 38 is used to shoot the tip of the needle 37. When the droplet is formed and falls, the camera 38 captures the dynamic process of the droplet falling and transmits the animation to the video collector. The digital processing unit automatically identifies the particle size of the droplet, and the central controller is connected to the power supply. According to the value of the particle size, the electric field voltage is corrected in real time by controlling the electric field power supply to achieve control of the particle size of the microcapsule.

[0045] Under normal conditions, the spring 34 applies elastic force to the mounting block 32 through the pin 33, ensuring that the mounting block 32 is tightly fitted with the mounting protrusion 35, so that the annular notch formed by the combination of the first semi-annular notch 321 and the second semi-annular notch 351 can firmly clamp the needle 37. In actual operation, the user can pull the mounting block 32 away from the mounting protrusion 35, thereby driving the pin 33 to move and compressing the spring 34 at the same time. At this time, the needle 37 can be easily inserted between the mounting block 32 and the mounting protrusion 35. When the mounting block 32 is released, the elastic force of the spring 34 causes it to return to its original position, and the first semi-annular notch 321 is tightly combined with the second semi-annular notch 351 to firmly clamp the needle 37. The entire installation process is simple and convenient, and the operation is stable and reliable.

[0046] Specifically, the pin 33 is provided with a contact surface 332 that contacts the spring 34, and one end of the spring 34 directly presses against the contact surface 332. The design of the contact surface 332 ensures that the spring 34 can stably act on the pin 33 when compressed or released, thereby effectively transmitting the elastic force and ensuring the tight fit between the mounting block 32 and the mounting protrusion 35. With the existence of the contact surface 332, the spring 34 can apply force more evenly, thereby improving the stability and reliability of the overall structure.

[0047] The above specific implementations do not constitute a limitation on the protection scope of the present invention. It should be understood by those skilled in the art that various modifications, combinations, sub-combinations and substitutions can be made according to design requirements and other factors. Any modification, equivalent substitution and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A microcapsule preparation device with adjustable electric field, characterized in that: include: A base (1), a support arm (2), a movable arm (3), a positive metal sheet (4), a negative electrode ring (5) and a negative electrode metal sheet (6); the movable arm (3) is slidably connected to the support arm (2); the positive electrode metal sheet (4) is arranged on the movable arm (3); a support structure (9) is arranged on the upper surface of the base (1); the support arm (2) is connected to the support structure (9); the negative electrode ring (5) is connected to the support structure (9); the positive electrode metal sheet (4) is located on the upper side of the negative electrode ring (5); the movable arm (3) can drive the positive electrode metal sheet (4) to approach or move away from the negative electrode ring (5); the negative electrode metal sheet (6) is arranged on the upper surface of the base (1).

2. The device for preparing microcapsules with adjustable electric field according to claim 1, characterized in that: The support arm (2) is provided with a slideway (21) having a trapezoidal cross section, and the movable arm (3) extends into the slideway (21) and is slidably connected to the slideway (21); the microcapsule preparation device with adjustable electric field further comprises a first adjustment component (7), the first adjustment component (7) comprising a fixed arm (71), an adjustment screw (72) and a limit portion (73); the fixed arm (71) is fixedly connected to the support arm (2), the adjustment screw (72) passes through the fixed arm (71) and is threadedly connected to the fixed arm (71), the adjustment screw (72) passes through the movable arm (3) and is rotatably connected to the movable arm (3), and the limit portion (73) is connected to the lower end of the adjustment screw (72).

3. The device for preparing microcapsules with adjustable electric field according to claim 1, characterized in that: The upper surface of the base (1) is provided with a placement groove (11) for placing a beaker (8), and the negative electrode metal sheet (6) is arranged in the placement groove (11).

4. The device for preparing microcapsules with adjustable electric field according to claim 1, characterized in that: A handle (74) is provided at the upper end of the adjusting screw rod (72).

5. The device for preparing microcapsules with adjustable electric field according to claim 1, characterized in that: The support structure (9) comprises a support column (91) and a second adjustment component (92); the support column (91) is fixedly connected to the upper surface of the base (1), and the second adjustment component (92) is connected to the support column (91).

6. The device for preparing microcapsules with adjustable electric field according to claim 5, characterized in that: The second adjustment component (92) comprises: a connecting arm (921), a mounting ring (922) and four driving components (923); the negative electrode ring (5) is composed of four arc-shaped metal plates (51); the connecting arm (921) is fixedly connected to the support column (91), one end of the connecting arm (921) away from the support column (91) is fixedly connected to the mounting ring (922), and the four arc-shaped metal plates (51) are connected to the mounting ring (922) via the driving component (923); The driving assembly (923) comprises a second motor (9231), a wire wheel (9232), a metal wire (9233), a first guide column (9234) and a second spring (9235); the second motor (9231) is fixedly mounted on the outside of the mounting ring (922); the wire wheel (9232) is connected to the output end of the second motor (9231); one end of the metal wire (9233) is fixedly connected to the wire wheel (9232); the metal wire (9233) passes through the mounting ring (922) and is slidably connected to the mounting ring (922); One end of the wire (9233) away from the wire wheel (9232) is connected to the second motor (9231), the first guide column (9234) passes through the mounting ring (922) and is slidably connected to the mounting ring (922), the first guide column (9234) is fixedly connected to the arc-shaped metal plate (51), the second spring (9235) is sleeved on the first guide column (9234), one end of the second spring (9235) is connected to the mounting ring (922), and the other end of the second spring (9235) is in contact with the arc-shaped metal plate (51).

7. The device for preparing microcapsules with adjustable electric field according to claim 6, characterized in that: A contact ring (9236) is sleeved on the metal wire (9233), the contact ring (9236) is slidably connected to the metal wire (9233), and the contact ring (9236) is connected to a connector (9238) via a conductor (9237).

8. The device for preparing microcapsules with adjustable electric field according to claim 5, characterized in that: The support structure (9) further comprises an adjustment platform (93), wherein the adjustment platform (93) comprises: a slot body (931), a first moving block (932), a first lead screw (933), a first motor (934), a second moving block (935), a second lead screw (936), a third motor (937) and a second guide column (938); the slot body (931) is fixedly connected to the upper end of the support column (91); the first moving block (932) is slidably mounted in a movable slot of the slot body (931); the first lead screw (933) passes through the slot body (931) and is rotationally connected to the slot body (931); and the first motor (934) is connected to the first lead screw (933) and is used to drive the first lead screw (93 3) rotation, the first lead screw (933) passes through the first moving block (932) and is threadedly connected to the first moving block (932), the second guide column (938) is fixedly connected to the first moving block (932), the second lead screw (936) is rotationally connected to the first moving block (932), the third motor (937) is connected to the second lead screw (936) and is used to drive the second lead screw (936) to rotate, the second moving block (935) is slidably connected to the second guide column (938), the second lead screw (936) passes through the second moving block (935) and is threadedly connected to the second moving block (935), and the second moving block (935) is fixedly connected to the support arm (2).

9. The device for preparing microcapsules with adjustable electric field according to claim 1, characterized in that: The movable arm (3) comprises a main body (31), a mounting block (32), two pins (33), two first springs (34) and a mounting protrusion (35); the mounting protrusion (35) is fixedly connected to the main body (31) and is an integral structure; the mounting block (32) is provided with a first semi-annular notch (321), the mounting protrusion (35) is provided with a second semi-annular notch (351), the mounting protrusion (35) is provided with two spring grooves (352), the two first springs (34) are arranged in the spring grooves (352), the two pins (33) are provided with a first spring groove (352), and the two first springs (34) are provided in the spring grooves (352). 33) passes through the mounting block (32), the spring groove (352) and the first spring (34), connecting the mounting block (32) and the mounting protrusion (35); the first semi-annular notch (321) and the second semi-annular notch (351) form an annular notch for accommodating the needle (37); the two first springs (34) provide elastic force for the pin shaft (33) in a direction close to the main body (31), and a limiting cap (331) is provided at one end of the two pin shafts (33) away from the main body (31); and a camera (38) is installed on the lower surface of the main body (31).

10. The device for preparing microcapsules with adjustable electric field according to claim 1, characterized in that: A contact surface (332) is provided on the pin shaft (33), and the first spring (34) is in contact with the contact surface (332); support portions (36) matching the needle head (37) are provided in the first semi-annular notch (321) and the second semi-annular notch (351), respectively, and the positive electrode metal sheet (4) is provided on the support portions (36).

Images