Granular ball, preparation method thereof and product containing granular ball

Abstract

The invention discloses a granular ball, a preparation method thereof and a product containing the granular ball, and belongs to the technical field of health care. The granules are prepared from the following raw materials in parts by weight: 500-650 parts of vegetation matrix material powder, 80-140 parts of an excipient and 250-350 parts of a traditional Chinese medicine concentrated solution, the grass and tree matrix material powder is selected from bamboo, wood, straw or grass powder, and the excipient is selected from clayey soil, loam, sandy soil, red loam, yellow loam, black soil, desert soil, wet soil, lithologic soil or high mountain soil; the particle size of the grass and tree matrix material powder is 80-200 meshes; the traditional Chinese medicine concentrated solution is a concentrated solution containing traditional Chinese medicine components; the granular ball is obtained by mixing, granulating and polishing raw materials, and the size of the granular ball is 5-8mm. The pillow containing the particles is good in overall performance, so that the pillow has good use experience. The particles have high hardness and fluidity and low hygroscopicity and powder falling rate, and volatile components can be released for a long time.

Description

Technical Field

[0001] The invention belongs to the technical field of health care, and particularly relates to a granular ball and a preparation method thereof and a product containing the granular ball, and more particularly to a pillow containing special granules. Background Art

[0002] The history of medicinal pillow therapy is long. People in ancient my country have long discovered that sleeping with a pillow filled with medicine (i.e., a medicinal pillow) can play a good role in disease prevention and health care, and can prevent and treat a variety of chronic diseases, thus forming a unique "medicinal pillow therapy". As early as the Jin Dynasty, Ge Hong's "Emergency Prescriptions for the Elbow" recorded that soybeans were put into pillows to treat insomnia patients. Sun Simiao's "Thousand Gold Prescriptions" contains "a prescription for treating stiff neck and head, and not being able to look around. Steam a bucket of soybeans, make them change color, and use them as pillows in the inner capsule." Li Shizhen, a great medical scientist in the Ming Dynasty, recorded in "Compendium of Materia Medica" that many pillow therapy prescriptions such as mung bean pillows, evodia pillows, cassia chrysanthemum pillows, and silkworm feces pillows were used in clinical practice, which had significant effects on preventing and treating hypertension, headaches, insomnia, and cervical spondylosis.

[0003] In the prior art, the Chinese medicine is usually directly filled into the medicine pillow or the Chinese medicine is made into granules and filled into the medicine pillow.

[0004] For example, the patent application number CN201310720549.3 discloses a production process of a Taxus chinensis health pillow, which includes the following steps: a) Raw material cleaning: clean the fresh branches, leaves, stems and bark of the cut yew with running water and dry the surface moisture; b) Branch slices: Cut the dried branches, leaves, stems and bark into long strips with a length of 0.5-2.5mm; c) Material ratio: the materials are as follows by weight: 80% of the long flaky raw material obtained in step b), 2% of magnetite, 5% of schizonepeta tenuifolia, 3% of floating wheat, 2% of spiny jujube kernel, 3% of polygala tenuifolia, 3% of polyphylla polyphylla, and 2% of julibrissin bark; d) Material crushing: crush the materials prepared in step c) into 100-mesh powder using a high-speed turbine crusher; e) Mixing and refining medicine: put the powder obtained in step d) into a blender and then add water to mix into a medicine mass; f) Pill making: 1. Remove the upper cover and gear box cover of the pill making machine, add a few drops of anhydrous edible oil to each oil hole, and then use medical alcohol to wipe the roller and the parts in contact with it for disinfection; 2. Reinstall the upper cover and gear cover, turn on the power, turn on the switch, and run the empty machine for 1-2 minutes; 3. Take an appropriate amount of the evenly stirred medicine mass and put it into the extrusion slot of the pill making machine for cake pressing, then put the cake-shaped medicine material into the strip forming slot to form strips, and then put the completed medicine strips horizontally in the pill making slot to directly rub them into pills; g) Particle polishing: Put an appropriate amount of pills in the sugar coating machine for polishing, and dry them after polishing; h) Coating and fragrance preservation: When the pills in the sugar coating machine are dry, spray the corn slurry into the sugar coating machine step by step by spraying, start the sugar coating machine, and the pills are coated in the continuous rolling of the sugar coating machine; i) High temperature disinfection: After the pills are coated, they are placed in an electric constant temperature drying oven and sterilized at a high temperature of 170 degrees Celsius for 30 minutes; j) Low temperature storage: The high temperature sterilized pills are first placed in a wooden container to let them cool naturally. After they are cooled to room temperature, they are packed in bags and stored in a ventilated and cool place; k) Medicine bag sewing: Use non-woven fabric with good air permeability to make medicine bags of different specifications; l) Medicine bag filling: The sewn medicine bags of different specifications are filled with different amounts of pills according to different specifications and sealed; m) Pillow core sewing: Sewing pillow core covers of different specifications that can hold medicine bags; n) Finished product filling: According to different pillow product specifications, different amounts of medicine bags are put into the pillow core cover, and the interlayer of the pillow core cover is supported and opened with the tool for packaging medicine bags, and the medicine bags are put into the cover and sealed. The finished health pillow is fully packaged; o) Packaging and warehousing: The finished health pillows filled with medicine bags are packaged and warehousing.

[0005] This patent uses Chinese medicine powder as raw material to prepare granules, and the process is complicated; the granules are soft and easy to fall off.

[0006] For example, the patent with application number CN202010000991.9 discloses a method for making a Chinese medicine composition sleeping-aiding pillow, with borneol, thuja, valerian root, amber, tangerine peel, poria, polygala, julibrissin bark, silkworm feces, rosemary, lavender, and jujube kernel as basic components, supplemented by other components including snow chrysanthemum, gardenia, cassia seed, calamus, herba rejuvenae, lily, tiger whip, cynomorium songaricum, rhizoma annuae, curculigo orchioides, apocynum venetum, gastrodia elata, chrysanthemum, mistletoe, selfhealing herb, uncaria, atractylodes rhizome, celery seed, sophora japonica flower, cistanche deserticola, rose, patchouli, ligusticum chuanxiong, angelica dahurica, gastrodia elata, and alkyl oxyphylla. The Chinese medicine pieces are ground into extremely fine powder for use, then mixed with low molecular weight polyethylene and aluminate coupling agent to make granules, which are then put into a pillowcase with a polyurethane base material to make the product.

[0007] This patent uses traditional Chinese medicine powder as raw material and adds low molecular weight polyethylene and aluminate coupling agents to prepare particles.

[0008] For example, the patent application number CN201810823704.7 discloses a method for producing a medicinal pillow filled with Chinese medicine particles, which is produced by the following steps: (1) drying or sun-drying the Chinese medicine materials for producing the medicinal pillow; (2) crushing the dried Chinese medicine materials for processing the medicinal pillow into a powder of 60-80 mesh; (3) introducing the Chinese medicine powder into a blender according to the medicinal pillow material ratio, adding 8% edible starch as a binder, and then adding water in a ratio of 3:1, and then mixing evenly; (4) passing the mixed Chinese medicine through a pill making machine to make particles with a diameter of 5 mm; (5) drying the Chinese medicine particles and keeping the moisture content within 10%; (6) using dustproof cloth or non-woven fabric to make a pillow core inner bag, and putting the Chinese medicine particles into the pillow core inner bag to make a medicinal pillow; the medicinal pillow material ratio is a weight ratio of medicinal particles to buckwheat husks of 7:3.

[0009] This patent uses Chinese medicine powder as raw material and adds edible starch to prepare granules.

[0010] The applicant found that the above technology has the following problems: (1) Traditional Chinese medicine has complex ingredients, and the powders of various traditional Chinese medicines may interact with each other or have different moisture absorption abilities, causing the product to be easily moldy or damp; (2) In order to ensure the molding, it is usually necessary to add adhesives, such as polymer materials. The adhesives not only play a health-care role, but the polymer materials are also not easy to degrade; (3) The molding ability of Chinese medicine powder varies, which makes it difficult to control the hardness (and thus the fluidity and support of the particles) and it is easy to lose powder. Summary of the invention

[0011] In order to solve the above problems, the embodiment of the present invention provides a granular ball and a preparation method thereof and a product containing the granular ball. The Chinese medicine ingredients are added in the form of concentrated liquid, which serves as the effective ingredients of the Chinese medicine and the moisture during granulation. No additional water is needed during granulation. Excipients such as clay soil, loam, sandy soil, red soil, yellow soil, black soil, desert soil, wet soil, rock soil, mountain soil or mineral powder are used to ensure the hardness of the particles, and at the same time, the release rate of the effective ingredients can be controlled. The pure natural raw materials can be directly discarded (no need to consider degradation). The grass-based material powder is the main body, which is a natural material, easy to obtain, low cost, and has adsorption capacity for the concentrated liquid. The wood fiber and excipients are combined to ensure the hardness of the particles, and are not easy to absorb moisture or fall off. The technical scheme is as follows: On the one hand, an embodiment of the present invention provides a granular ball, which is made of the following raw materials in parts by weight: 500-650 parts of plant-based material powder, 80-140 parts of excipients and 250-350 parts of Chinese medicine concentrate. The plant-based material powder is selected from bamboo, wood, straw or grass powder, etc. The plant-based material powder is mainly taken from natural plants, such as: bamboo plants of the genus Poaceae, crop straw, herbaceous plants, seed plants, woody plants, flowering plants, aquatic plants, spore plants, medicinal plants or vines. The excipient is selected from clay soil, loam, sandy soil, red soil, yellow soil, black soil, desert soil, wet soil, rock soil or alpine soil and other viscous soil. The particle size of the plant-based material powder is 80-200 mesh. The Chinese medicine concentrate is a concentrate containing Chinese medicine ingredients. Traditional Chinese medicine concentrates mainly include concentrates obtained by traditional methods and modern methods, such as decoction, percolation, reflux, evaporation concentration, steam distillation, membrane separation concentration and adsorption concentration. The granules are obtained by mixing, granulating and polishing the raw materials. The size of the granules is 5-8mm, the compressive strength is 58-65N, and the bulk density is 1.21-1.27g / cm 3 .

[0012] Preferably, the granular balls of this patent are made of the following raw materials in parts by weight: 550-600 parts of plant-based material powder, 110-120 parts of excipients and 275-300 parts of traditional Chinese medicine concentrate.

[0013] Among them, the Chinese medicine concentrate is obtained by decocting or extracting the Chinese medicine.

[0014] Preferably, the plant-based material powder is selected from bamboo or wood powder, the excipient is selected from kaolin, red soil, yellow soil or clay soil, and the Chinese medicine concentrate is obtained by decocting the Chinese medicine. The decocting process is: decocting 1-3 times with water 3-10 times the weight of the Chinese medicine, combining the decoctions, and concentrating to 1 / 4-1 / 20 volume to obtain a concentrate.

[0015] More preferably, the granular ball of the present invention is made of the following raw materials in parts by weight: 600 parts of plant-based material powder, 120 parts of excipients and 300 parts of Chinese medicine concentrate. The plant-based material powder is wood powder. The excipient is selected from kaolin or loess. The Chinese medicine concentrate is obtained by decocting Chinese medicine.

[0016] On the other hand, the present invention also provides a product containing the aforementioned granular balls, which is a cushion, cover, support or enclosure, etc., and mainly plays a supporting role, including supporting the head, waist, legs or neck, etc. The product includes an outer cover and the aforementioned granular balls filled therein. Specifically, the product is a pillow.

[0017] In another aspect, an embodiment of the present invention further provides a method for preparing the aforementioned granular ball, the method comprising: S1 Mixing: Mix the herbal material powder, excipients and Chinese medicine concentrate according to the proportion.

[0018] S2 granulation: the mixed material obtained in step S1 is granulated to obtain particles with a particle size of 5-8 mm.

[0019] S3 polishing: polishing the particles obtained in step S2 to obtain particles with smooth surfaces.

[0020] S4 drying and cooling: drying and cooling the particles in step S3 to obtain a product.

[0021] Furthermore, before step S1, the plant-based material powder is sterilized; or after step S4, the product is sterilized. The sterilization process includes high temperature, microwave or ultraviolet irradiation, etc., to ensure that the bacteria and fungi indicators of the particles meet the use requirements. The technical solution provided by the embodiment of the present invention has the following beneficial effects: (1) The Chinese medicine ingredients are added in the form of concentrated liquid, which serves as the effective ingredients of the Chinese medicine and the moisture during granulation. No additional water is needed during granulation. Excipients such as clay soil, loam, sandy soil, red soil, yellow soil, black soil, desert soil, wet soil, rock soil or alpine soil are used to ensure the hardness of the particles and control the release rate of the effective ingredients. They are pure natural raw materials and can be directly discarded (no need to consider degradation). The main body is the powder of plant-based materials, which is a natural material that is easy to obtain, low in cost, and has the ability to absorb concentrated liquid. The wood fiber therein cooperates with the excipient to ensure the hardness of the particles, and is not easy to absorb moisture or fall off.

[0022] (2) The processing is simple, usually only requiring crushing, granulation, polishing and drying.

[0023] (3) The particles are round and uniform in size, and the product has good fluidity. The gaps between the particles can improve air permeability; the good fluidity of the particles allows the particles to move freely and distribute more closely to the physiological curves of the head and neck, providing support and tactile traction massage, while dispersing the pressure on the head and neck, which is especially suitable for people who need to maintain a fixed posture for a long time.

[0024] (4) The effective ingredients of traditional Chinese medicine are released slowly over a long period of time and can be used for a long time. The granules can be stored for a long time and will not mold or absorb moisture even if stored for more than two years.

[0025] (5) Flexible production: different Chinese medicine concentrates can be added as needed to obtain health pillows with different functions, without having to consider the moisture absorption, powder loss, hardness, etc. of the Chinese medicine powder.

[0026] (6) According to the need for compatibility, different release capacities, or mutual reactions, different Chinese medicine concentrates can be used to make granules (adjusting the ratio of herbal base material powder, excipients, and Chinese medicine concentrates as needed), and then the different granules can be filled into the pillowcase to ensure better results. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a flow chart of the method for preparing granular balls in an embodiment of the present invention. DETAILED DESCRIPTION

[0028] In order to make the objectives, technical solutions and advantages of the present invention more clear, the present invention will be further described in detail below with reference to the accompanying drawings.

[0029] Example 1 Embodiment 1 provides a method for preparing granular balls, the method comprising: S1 Mixing: 600 parts by weight of wood powder (size: 100 m), 120 parts by weight of kaolin and 300 parts by weight of traditional Chinese medicine concentrate are mixed.

[0030] S2 granulation: the mixed material obtained in step S1 is granulated to obtain particles with a particle size of 6 mm.

[0031] S3 polishing: polishing the particles obtained in step S2 to obtain particles with smooth surfaces.

[0032] S4 drying and cooling: drying and cooling the particles in step S3 to obtain a product.

[0033] S5 Sterilization: Use microwaves to sterilize the product.

[0034] The test results show that the compressive strength of the produced particles is 63N and the bulk density is 1.25g / cm 3 .

[0035] Example 2 Embodiment 2 provides a method for preparing a granular ball, the method comprising: S1 Mixing: 550 parts by weight of bamboo powder (size: 100 m), 100 parts by weight of red soil and 270 parts by weight of Chinese medicine concentrate are mixed.

[0036] S2 granulation: the mixed material obtained in step S1 is granulated to obtain particles with a particle size of 6 mm.

[0037] S3 polishing: polishing the particles obtained in step S2 to obtain particles with smooth surfaces.

[0038] S4 drying and cooling: drying and cooling the particles in step S3 to obtain a product.

[0039] S5 Sterilization: Use microwaves to sterilize the product.

[0040] The test results show that the compressive strength of the produced particles is 62N and the bulk density is 1.24g / cm 3 .

[0041] Example 3 Embodiment 3 provides a method for preparing a granular ball, the method comprising: S1 Mixing: 580 parts by weight of wood powder (size 150 m), 50 parts by weight of yellow loam, 60 parts by weight of clay soil and 300 parts by weight of Chinese medicine concentrate are mixed.

[0042] S2 granulation: the mixed material obtained in step S1 is granulated to obtain particles with a particle size of 5 mm.

[0043] S3 polishing: polishing the particles obtained in step S2 to obtain particles with smooth surfaces.

[0044] S4 drying and cooling: drying and cooling the particles in step S3 to obtain a product.

[0045] S5 Sterilization: Use ultraviolet rays to sterilize the product.

[0046] The test results show that the compressive strength of the produced particles is 61N and the bulk density is 1.20g / cm 3 .

[0047] Example 4 Embodiment 4 provides a method for preparing granular balls, the method comprising: S1 Mixing: 300 parts by weight of bamboo powder (size: 100 m), 320 parts by weight of wood powder (size: 100 m), 60 parts by weight of yellow soil, 60 parts by weight of red soil and 280 parts by weight of Chinese medicine concentrate are mixed.

[0048] S2 granulation: the mixed material obtained in step S1 is granulated to obtain particles with a particle size of 7.5 mm.

[0049] S3 polishing: polishing the particles obtained in step S2 to obtain particles with smooth surfaces.

[0050] S4 drying and cooling: drying and cooling the particles in step S3 to obtain a product.

[0051] S5 Sterilization: Use ultraviolet rays to sterilize the product.

[0052] After testing, the compressive strength of the produced particles is 63N and the bulk density is 1.23g / cm 3 .

[0053] Verification Example Taking a pillow as an example, the size of the pillowcase is 50cm*75cm, and the material of the pillowcase is cotton. The pillowcase is filled with particles, and the filling amount is consistent with the prior art.

[0054] The Chinese medicinal ingredients (by weight) are: 10-20 parts of mugwort leaves, 10-20 parts of mint and 10-20 parts of cassia seeds.

[0055] In comparative example 1, the above components were crushed and directly made into granules according to the method of patent CN201310720549.3.

[0056] In comparative example 2, the above components were crushed and made into granules according to the method of patent CN202010000991.9.

[0057] In comparative example 3, the above components were crushed and made into granules according to the method of patent CN201810823704.7.

[0058] In Example 1, the above components were crushed, and a Chinese medicine concentrate was prepared by decocting, and granules were prepared by the method of Example 1.

[0059] Test 1: simulate the hygroscopicity under high humidity. The temperature is 30℃, the relative humidity is 75%; the pillow is not moved; after three months, the weight gain ratio of the particles is tested. The results are shown in Table 1: Table 1

[0060] As can be seen from Table 1, the moisture absorption rate of the particles prepared in Example 1 is low, which is similar to that of Comparative Example 2.

[0061] Test 2, simulated powder loss rate under use. At a temperature of 25°C and a relative humidity of 10%, the pillow was slapped at a low speed (simulating the rolling of a human head on the pillow, with a slapping frequency of 10 times / h). After six months, the powder was sieved out through a sieve and the weight loss ratio of the particles was tested. The results are shown in Table 2: Table 2

[0062] As can be seen from Table 1, the particles prepared in Example 1 have less powder loss.

[0063] Test three, simulates the retention effect of the active ingredients under the use state. Volatile fragrances (commercially available car liquid fragrances, added in an amount of 5%) were added during the preparation process of the particles in Example 1 and Comparative Examples 1-3. At a temperature of 25°C and a relative humidity of 50%, the pillow was slapped at a low speed (simulating the rolling of a human head on the pillow, with a slapping frequency of 20 times / h). The particles were taken out for testing every 15 days. The testing process was as follows: 10 particles were randomly selected by the same five experimenters; for each experimenter, if more than 5 particles had fragrance, the experimenter believed that the fragrance was maintained. If more than or equal to 3 experimenters believed that the fragrance was maintained, the fragrance of the particles was considered to be maintained. The number of days the fragrance was maintained was recorded. The results are shown in Table 3: Table 3

[0064] As can be seen from Table 3, the particles prepared in Example 1 can maintain fragrance for a long time, so it can be reasonably inferred that the volatile effective ingredients of traditional Chinese medicine can be maintained for a long time.

[0065] Experiment 4: The compressive strength and bulk density of the single particles prepared in Example 1 and Comparative Examples 1-3 were tested. The results are shown in Table 4: Table 4

[0066] It can be seen from Table 4 that the particles prepared in Example 1 have higher hardness and higher packing density; it can be inferred that they have higher supportability and fluidity.

[0067] Experiment 5, user experience evaluation. The usage time is 60 days, from October to December 2023, and the sleep is for one person. There are 7 subjects, including 4 males and 3 females, with an average age of 28.57 years old, a youngest age of 24 years old, and an oldest age of 41 years old. The subjects all have normal sleep. Among them, the standard is: one point for bad, two points for average, three points for good, and four points for particularly good. The score processing method is: remove the maximum and minimum values, and then take the average. The results are shown in Table 5: Table 5

[0068] It can be seen from Table 5 that the pillow filled with the particles prepared in Example 1 has a better user experience.

[0069] In summary, the overall performance of the pillow containing the patented particles is good, which gives the pillow a good user experience. The particles have high hardness and fluidity, low hygroscopicity and powder loss rate, and at the same time, the volatile components can be released for a long time.

[0070] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A granular ball, characterized in that: The invention is prepared from the following raw materials in parts by weight: 500-650 parts of plant-based material powder, 80-140 parts of excipients and 250-350 parts of concentrated Chinese medicine solution; the plant-based material powder is selected from bamboo, wood, straw or grass powder, the excipient is selected from clay soil, loam, sandy soil, red soil, yellow soil, black soil, desert soil, wet soil, rocky soil or alpine soil; the particle size of the plant-based material powder is 80-200 meshes; the concentrated Chinese medicine solution is a concentrated solution containing Chinese medicine ingredients; the granular ball is obtained by mixing, granulating and polishing the raw materials, and the size of the granular ball is 5-8 mm.

2. The granular ball according to claim 1, characterized in that: The invention is prepared from the following raw materials in parts by weight: 550-600 parts of plant-based material powder, 110-120 parts of excipients and 275-300 parts of traditional Chinese medicine concentrated liquid.

3. The granular ball according to claim 1, characterized in that: The traditional Chinese medicine concentrated solution is obtained by decocting or extracting the traditional Chinese medicine.

4. The granular ball according to claim 1, characterized in that: The plant-based material powder is selected from bamboo or wood powder, the excipient is selected from kaolin, red soil, yellow soil or clay soil, and the traditional Chinese medicine concentrate is obtained by decocting the traditional Chinese medicine.

5. The granular ball according to claim 1, characterized in that: The invention is prepared from the following raw materials in parts by weight: 600 parts of plant-based material powder, 120 parts of excipients and 300 parts of Chinese medicine concentrate; the plant-based material powder is wood powder; the excipient is selected from kaolin or loess; the Chinese medicine concentrate is obtained by decocting Chinese medicine.

6. A product containing the granular balls according to any one of claims 1 to 5, the product being a cushion, a sleeve, a support or a surround, the product comprising an outer sleeve and the granular balls filled therein.

7. The product according to claim 6, characterized in that This product is a pillow.

8. The method for preparing granular balls according to claim 1, characterized in that: The method comprises: S1: mixing the herb-based material powder, excipients and Chinese medicine concentrate according to the proportion; S2 granulation: granulating the mixture obtained in step S1 to obtain particles with a particle size of 5-8 mm; S3 polishing: polishing the particles obtained in step S2 to obtain particles with smooth surfaces; S4 drying and cooling: drying and cooling the particles in step S3 to obtain a product.

9. The preparation method according to claim 8, characterized in that: Before step S1, the plant-based material powder is sterilized; or after step S4, the product is sterilized.

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