Ginseng nourishing honey paste based on hot pulping system and preparation method of ginseng nourishing honey paste
Through the application of the hot refining system, the problem of low efficiency in the treatment of solid waste and extraction of active ingredients in traditional Chinese medicine was solved, the efficient utilization of traditional Chinese medicine resources and the complete separation of medicinal ingredients were achieved, and excellent drugs for the treatment of new coronary syndrome were obtained.
Patent Information
- Application Number
- CN202410901973.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-05
- Publication Date
- 2025-02-18
AI Technical Summary
The solid waste generated in the traditional Chinese medicine manufacturing industry accounts for more than 70% of the total amount. Traditional treatment methods lead to waste of biomass resources and the efficiency of extracting effective ingredients of traditional Chinese medicine is low.
The hot slurry system is adopted to achieve the complete extraction rate of the active ingredients of traditional Chinese medicine and the complete separation of medicinal and non-medical ingredients through steps such as forging, steam rubbing, high-concentration refining and slurry separation.
The complete separation of Chinese medicine fibers, lignin and other substances from medicinal ingredients was achieved, and the residue was turned into useful materials for papermaking or making wooden boards, which improved the utilization rate of Chinese medicine resources and obtained a good treatment for the novel coronavirus syndrome. drug.
Smart Images

Figure FT_1 
Figure SMS_1
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of traditional Chinese medicine extraction, and in particular to a ginseng nourishing honey paste based on a hot grinding system and a preparation method thereof. Background Art
[0002] In the 1930s, Asplund of Sunds developed the first hot refiner in the papermaking industry. Through high-speed rotating grinding discs and heat, wood or other plant fiber raw materials were refined into fibers, so that plant fibers and non-fibrous materials were effectively separated, which made a qualitative leap in mechanical papermaking technology. Entering the 20th century, the latest series of hot refiners have greatly improved the separation quality of fibers and resin glue. The hot refiner has a compact structure, strong power, simple operation and maintenance, and a wider range of applications. For example, the invented high-concentration pulping machine uses a dynamic grinding disc and a static grinding disc to form a grinding zone. The fiber raw material is continuously pushed into the grinding zone by a strong feeding device. In the grinding zone, it is subjected to the strong mechanical action of the grinding disc and the mutual friction between fibers. It is repeatedly crushed, dissociated, torn, and filamented, and finally obtains a pulp with a certain degree of freeness. The high-concentration pulping machine can use a variety of papermaking raw materials that were originally unusable, such as shrubs and branches, to produce high-quality paper.
[0003] While the current Chinese patent medicine manufacturing industry has generated huge economic and social benefits, it has also brought major problems to the ecosystem and sustainable development, mainly reflected in the amount of solid waste from Chinese medicine waste, which accounts for more than 70% of the total solid waste from Chinese medicine. In addition to a large amount of biomass such as cellulose, hemicellulose and lignin, these solid wastes from Chinese medicine also contain a large amount of effective medicinal ingredients such as polysaccharides, polypeptides, nucleic acids, vitamins, etc. Traditional methods of handling solid waste generated during Chinese medicine processing, such as landfill, composting, preparation of fermentation matrix, incineration and other extensive methods, have caused a huge waste of biomass resources.
[0004] Ginseng Yangrong Pills, derived from Shiquan Dabu Decoction, come from the "Taiping Huimin Hejijufang" of the Song Dynasty. It is recorded in the article that Ginseng Yangrong Pills "treats fatigue, stagnation of limbs, and pain in bones and flesh". For more than 900 years, it has been widely used by doctors to treat qi and blood deficiency with excellent results. This prescription is composed of 14 herbs: astragalus, cinnamon, angelica, white peony, cooked rehmannia, ginseng, white atractylodes, poria, licorice, schisandra, polygala, tangerine peel, ginger, and jujube. The whole prescription of Ginseng Yangrong Pills is used together to replenish qi and strengthen the spleen, replenish blood and harmonize the liver, and calm the mind and tranquilize the nerves. It is suitable for many symptoms such as asthenia, insomnia, palpitations, and menstrual disorders.
[0005] In addition, pharmacological studies on Ginseng Yangrong Pills have shown that Ginseng Yangrong Pills can enhance the immune function of cells and be used in the treatment of tumors; Ginseng Yangrong Pills can increase hemoglobin and red blood cell counts and be used in the treatment of anemia; Ginseng Yangrong Pills can improve the symptoms of children's ADHD and anorexia by regulating the spleen and stomach qi and blood, calming the mind and calming the spirit; Ginseng Yangrong Pills can effectively regulate the level of inflammatory factors in patients with atrial fibrillation, and can reduce the recurrence rate of patients after atrial fibrillation ablation, thereby improving the quality of life of patients; Ginseng Yangrong Pills can combine with anti-tuberculosis drugs and their metabolites to form low-toxic products, or directly counteract the liver damage caused by them and protect liver cells. Our research also shows that after further chemical loading, Ginseng Yangrong Pills have very good therapeutic effects on the sequelae of new coronavirus infection such as shortness of breath, fatigue, shortness of breath and difficulty sleeping. Summary of the invention
[0006] In view of this, the present invention provides a ginseng nourishing honey paste based on a hot pulping system and a preparation method thereof. The present invention not only obtains the full extraction rate of effective ingredients of traditional Chinese medicine, realizes the complete separation of fiber, lignin and other substances in plant traditional Chinese medicine from medicinal ingredients, and solid waste such as traditional Chinese medicine residues becomes useful light industrial materials that can be turned into papermaking or wood boards, etc.; and obtains a drug with excellent effect in treating long-term new crown syndrome.
[0007] In a first aspect of the present disclosure, the present disclosure provides a hot refining system for extracting effective ingredients of traditional Chinese medicine, which comprises the following steps: S101 Feed the clean raw materials of Chinese medicinal plants into a special forging and crushing machine to crush them separately, and then mix them to obtain mixed medicinal powder; S102 The mixed powder obtained in S101 is fed into the steaming pipe through a forced feeding motor, and high-temperature steam is introduced into the steaming pipe to maintain the temperature at 105-165°C (for example: 105°C, 125°C, 145°C, 165°C); S103: starting the mechanical kneading function in the steaming pipe at a speed of 100-1500 rpm (for example, 100, 300, 500, 700, 900, 1100, 1300, 1500 rpm) to obtain mixed medicinal material fines; S104 The mixed medicinal material fine material after mechanical kneading is sent to the high-concentration pulping machine (see attached) through a forced feeding motor. Figure 1 ), start the motor, control the speed at 500-1500 rpm (for example: 500, 750, 1000, 1250, 1500 rpm), maintain the refining time for 30-75 minutes (profit: 30, 45, 60, 75 minutes), and obtain a high-concentration slurry of mixed medicinal materials; S105 The mixed medicinal material high-concentration slurry obtained in S104 is sent to a press dewatering machine through a forced feeding motor for pulp-residue separation, and the residue is recycled. The coarse high-concentration slurry is filtered twice using a plate and frame filter to obtain a fine mixed high-concentration slurry.
[0008] In a second aspect of the present disclosure, the present disclosure provides a fine mixed high-concentration slurry prepared by the hot refining system of the first aspect; In some optional embodiments of the present disclosure, the finely mixed high-concentration medicinal slurry contained in the ginseng nourishing honey paste contains, by weight, 100 parts of red ginseng, 25 parts of cordyceps, 25 parts of dendrobium, 100 parts of atractylodes, 75 parts of tuckahoe, 100 parts of angelica, 75 parts of rehmannia root, 100 parts of white peony, 100 parts of astragalus, 100 parts of polygonatum, 100 parts of tangerine peel, 50 parts of polygala, 100 parts of cinnamon, 75 parts of schisandra, 100 parts of fritillaria, 75 parts of ophiopogon, 75 parts of cypress seed, 100 parts of spiny jujube seed, 100 parts of bupleurum, 50 parts of plantain, 50 parts of dried ginger, and 150 parts of licorice.
[0009] In a third aspect of the present disclosure, the present disclosure provides a method for preparing ginseng nourishing honey paste, comprising the following steps: S201 Put the donkey-hide gelatin into the paste-making pot, add 4-6 times the amount of pure water (for example: 4 times, 5 times, 6 times), start the mixer and heat it to 45-75℃ (for example: 45, 55, 65, 75℃), keep it warm for 6-12 hours (for example: 6, 8, 10, 12 hours); S202 Place the finely mixed, highly concentrated medicinal paste obtained in S105 into the paste-making pot in S201, start the mixer and raise the temperature to 75-95°C (for example, 75, 85, 95°C), add honey when the medicinal paste becomes thicker, stir evenly, stop heating and cool, and after passing quality inspection, fill and bottle to obtain the ginseng nourishing honey paste.
[0010] The ginseng nourishing honey paste disclosed in the present invention comprises a new pharmaceutical composition, and the composition ratio is calculated by weight: 80-120 parts of red ginseng, 5-45 parts of cordyceps, 5-45 parts of dendrobium, 80-120 parts of atractylodes, 55-95 parts of tuckahoe, 80-120 parts of angelica, 55-95 parts of rehmannia root, 80-120 parts of white peony root, 80-120 parts of astragalus, 80-120 parts of polygonatum, 80-120 parts of tangerine peel, 30-70 parts of polygala, 80-120 parts of cinnamon, 55-95 parts of schisandra, 80-120 parts of fritillaria, 55-95 parts of ophiopogon, 55-95 parts of cypress seed, 80-120 parts of spiny jujube seed, 80-120 parts of bupleurum, 30-70 parts of plantain, 30-70 parts of dried ginger, 130-170 parts of liquorice, 5-45 parts of donkey-hide gelatin, and 130-170 parts of honey.
[0011] In an optional embodiment of the present disclosure, the new drug combination of ginseng nourishing honey paste is calculated by weight: 100 parts of red ginseng, 25 parts of cordyceps, 25 parts of dendrobium, 100 parts of atractylodes, 75 parts of tuckahoe, 100 parts of angelica, 75 parts of rehmannia root, 100 parts of white peony root, 100 parts of astragalus, 100 parts of polygonatum, 100 parts of tangerine peel, 50 parts of polygala, 100 parts of cinnamon, 75 parts of schisandra, 100 parts of fritillaria, 75 parts of ophiopogon, 75 parts of cypress seed, 100 parts of spiny jujube seed, 100 parts of bupleurum, 50 parts of plantain, 50 parts of dried ginger, 150 parts of liquorice, 25 parts of donkey-hide gelatin, and 150 parts of honey.
[0012] In summary, the present invention utilizes a hot pulping system to extract effective components of traditional Chinese medicine, and realizes complete separation of medicinal components from non-medicinal components (such as fiber and lignin) of traditional Chinese medicine, and the drug residue can be completely transformed into useful light industrial materials; the environmental protection and ecological effects are very prominent. Further processing of traditional Chinese medicine preparations also becomes very simple, and the economic efficiency is greatly improved.
[0013] The honey paste prepared by the present invention has significant advantages compared with conventional dosage forms: BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a high-consistency hot pulping machine and the main equipment of the hot pulping system. DETAILED DESCRIPTION
[0015] The present disclosure is further described in detail below in conjunction with embodiments.
[0016] S001 100 parts of red ginseng, 25 parts of cordyceps, 100 parts of atractylodes macrocephala, 75 parts of tuckahoe, 75 parts of rehmannia root, 75 parts of schisandra chinensis, 100 parts of fritillaria, 75 parts of ophiopogon japonicus, 75 parts of cypress seed, 100 parts of spiny jujube seed and other medicinal materials are mixed and added into the hot refining system, and pure water 3 times of the total mass is added to the mixed medicinal materials when entering the high-concentration hot refining machine for refining, and finally the pulp residue is separated and the medicinal residue is removed to obtain medicinal pulp A; S002 Add 25 parts of Dendrobium, 100 parts of Angelica, 100 parts of White Peony, 100 parts of Radix Astragali, 100 parts of Polygonatum, 100 parts of Tangerine Peel, 50 parts of Polygala, 100 parts of Cinnamon, 100 parts of Bupleurum, 50 parts of Plantago, 50 parts of Dry Ginger, 150 parts of Licorice into the hot refining system, add 4 times of the total weight of the medicinal materials into the purified water when the mixed medicinal materials enter the high-concentration hot refining machine, and finally perform pulp-residue separation to remove the medicinal residue to obtain medicinal pulp B; S003 Mix the slurry A obtained in S001 and the slurry B obtained in S002 and put them into a slurry pot and paste pot, start the mixer and raise the temperature to 75-95℃ (for example: 75, 85, 95℃). When the slurry becomes thick, add 25 parts of donkey-hide gelatin powder and 150 parts of honey, stir evenly, stop heating and cool. After passing the quality inspection, fill it to obtain the ginseng nourishing honey paste.
[0017] The hot pulping system in this embodiment is based on the present disclosure and is composed of non-standard equipment including a forging crusher, a rotary kneading wire separator, a high-concentration hot pulping machine, a screw pulp-residue separator, etc., and is professionally used for the extraction of effective ingredients of traditional Chinese medicine containing plant fiber and lignin and the separation of non-medicinal ingredients.
[0018] In this embodiment, the hot pulping system described in the present disclosure includes processes such as slicing of plant-based Chinese medicinal materials, loading, steaming, kneading and silk separation, high-concentration hot pulping, and pulp-residue separation, forming a set of efficient and continuous Chinese herbal medicine effective ingredient extraction production line.
[0019] It is to be understood that the above embodiments are merely exemplary embodiments used to illustrate the principles of the present disclosure, but the present disclosure is not limited thereto. For those of ordinary skill in the art, various modifications and improvements can be made without departing from the spirit and substance of the present disclosure, and these modifications and improvements are also considered to be within the scope of protection of the present disclosure.
Claims
1. A hot pulping system for extracting effective ingredients from plant Chinese medicinal materials, characterized in that: It includes the following steps: S101 Feed the clean raw materials of Chinese medicinal plants into a special forging and crushing machine to crush them separately, and then mix them to obtain mixed medicinal powder; S102 The mixed powder obtained in S101 is fed into the steaming pipe through a forced feeding motor, and high-temperature steam is introduced into the steaming pipe to maintain the temperature at 105-165°C; S103: starting the mechanical kneading function in the steaming pipe at a speed of 100-1500 rpm to obtain mixed medicinal material fine material; S104 The mixed medicinal material fine material after mechanical kneading is fed into a high-concentration pulping machine (see Figure 1) through a forced feeding motor, the motor is started, the speed is controlled at 500-1500 rpm, and the pulping time is maintained for 30-75 minutes to obtain a mixed medicinal material high-concentration pulp; S105 The mixed medicinal material high-concentration slurry obtained in S104 is sent to a press dewatering machine through a forced feeding motor for pulp-residue separation, and the residue is recycled. The coarse high-concentration slurry is filtered twice using a plate and frame filter to obtain a fine mixed high-concentration slurry.
2. The hot refining system according to claim 1, characterized in that: The main engine is a high-consistency hot pulping machine which is a non-standard device. The structure of the main engine is shown in Figure 1 of the specification.
3. The hot refining system according to claim 1, characterized in that: It includes slicing, loading, steaming, kneading and silk separation, high-concentration hot grinding, and pulp-residue separation processes.
4. A ginseng nourishing honey paste and a preparation method thereof, characterized in that: It includes the following steps: S201 Put the donkey-hide gelatin into the paste-making pot, add 4-6 times the amount of purified water, start the mixer and heat it to 45-75℃, keep it warm for 6-12 hours; S202: Place the finely mixed, highly concentrated medicinal paste obtained in S105 into the paste-making pot in S201, start the mixer and raise the temperature to 75-95°C. When the medicinal paste becomes thicker, add honey, stir evenly, stop heating and cool. After passing the quality inspection, fill the paste to obtain the ginseng nourishing honey paste.
5. The ginseng nourishing honey paste according to claim 4, characterized in that: The novel pharmaceutical composition comprises the following components in parts by weight: 80-120 parts of red ginseng, 5-45 parts of cordyceps, 5-45 parts of dendrobium, 80-120 parts of atractylodes, 55-95 parts of tuckahoe, 80-120 parts of angelica, 55-95 parts of rehmannia root, 80-120 parts of white peony root, 80-120 parts of astragalus, 80-120 parts of polygonatum, 80-120 parts of tangerine peel, 30-70 parts of polygala, 80-120 parts of cinnamon, 55-95 parts of schisandra, 80-120 parts of fritillaria, 55-95 parts of ophiopogon, 55-95 parts of cypress seed, 80-120 parts of spiny jujube seed, 80-120 parts of bupleurum, 30-70 parts of plantain, 30-70 parts of dried ginger, 130-170 parts of liquorice, 5-45 parts of donkey-hide gelatin, and 130-170 parts of honey.