Device capable of quickly sorting rare cells in blood and use method of device

Abstract

The invention provides a device capable of rapidly sorting blood rare cells and a using method thereof, and belongs to the technical field of blood cell sorting.The device capable of rapidly sorting the blood rare cells comprises a supporting base, a supporting disc is fixedly arranged on the supporting base, a driving assembly is installed in the supporting base, and the driving assembly drives the supporting disc to rotate; the device comprises a driving assembly, a rotating disc is connected to the upper portion of the driving assembly, a supporting rod is fixedly arranged on the upper portion of the rotating disc, a shell is fixedly connected to the top of the supporting rod, a first connecting cylinder, a second connecting cylinder, a third connecting cylinder and a fourth connecting cylinder are arranged between the shell and the rotating disc, and an adjusting assembly is arranged below the first connecting cylinder. The cell sorting device solves the problems that an existing cell sorting device cannot adjust the size of a centrifugal sorting space according to the blood volume during centrifugal filtration, and cannot separate cells with different densities and sizes in the centrifugal separation process through a plurality of separation structures.

Description

Technical Field

[0001] The present invention relates to the technical field of blood cell sorting, and in particular to a device capable of rapidly sorting rare blood cells and a method for using the device. Background Art

[0002] Blood cell sorting is a key technology in biomedical research and clinical diagnosis, especially in the fields of oncology, immunology and stem cell research. Blood contains many types of cells, such as red blood cells, white blood cells and platelets, some of which are scarce and functionally specific. The separation and analysis of these rare cells are crucial for early disease diagnosis, treatment monitoring and basic research. Existing cell sorting devices still have some shortcomings.

[0003] The invention patent with publication number CN117778156A discloses a tumor cell cluster sorting and filtering device, comprising a filter cartridge, a fixed cartridge concentrically arranged inside the filter cartridge, a lower surface of the fixed cartridge rotatably connected to a concentrically arranged rotating ring, a support mechanism connected to the outer surface of the filter cartridge, and a liquid inlet mechanism connected to the filter cartridge. When in use, the hemispherical filter screen keeps rotating, and the mesh holes in the hemispherical filter screen deviate from the rotation center. Under the action of centrifugal force, the probability of tumor cell clusters adhered to the hemispherical filter screen entering the mesh holes in the hemispherical filter screen or even passing through the hemispherical filter screen under the impact of water flow is reduced, the probability of the hemispherical filter screen being blocked is reduced, and it is beneficial to the filtering of tumor cell clusters; at the same time, it is beneficial to the subsequent cleaning of the hemispherical filter screen, that is, it is beneficial to the cleaning of the tumor cell clusters on the hemispherical filter screen. Although the above device can clean up cell clusters, when in use, it is not possible to adjust the size of the centrifugal separation space according to the amount of blood during centrifugal filtration, and it is not possible to use multiple separation structures to allow the device to separate cells of different densities and sizes during centrifugal separation, which is not convenient for subsequent sorting of cells of different levels. Summary of the invention

[0004] In view of the problems existing in the existing blood cell sorting devices, the present invention is proposed.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: A device for rapidly sorting rare blood cells comprises a support seat, a support disk is fixedly arranged on the support seat, a driving assembly is installed in the support seat, a turntable is connected above the driving assembly, a support rod is fixedly arranged above the turntable, a shell is fixedly connected to the top of the support rod, a first connecting cylinder, a second connecting cylinder, a third connecting cylinder and a fourth connecting cylinder are arranged between the shell and the turntable, an adjustment assembly is arranged below the first connecting cylinder, a connection assembly is arranged below the second connecting cylinder, a second motor is installed on the support seat, a rotating block is connected to the output shaft of the second motor, a cover plate is hinged on the side of the shell, a rubber block and a counterweight block are fixedly connected to the cover plate, a filter cartridge is installed on the shell, an annular groove for the first connecting cylinder, the second connecting cylinder, the third connecting cylinder and the fourth connecting cylinder to pass through is opened on the filter cartridge, a bracket is fixedly arranged on the support seat, a lap ring is installed on the bracket, and the lap ring is rotatably connected to the adjustment assembly.

[0006] As a preferred solution of the present invention, the top of the support plate is rotatably connected with balls, the balls are evenly distributed along the circumference of the support plate, and the central axes of the support seat, support plate, turntable and shell are collinear.

[0007] As a preferred solution of the present invention, the driving assembly includes a first motor fixedly mounted on a support seat, a gear is fixedly connected to the output shaft of the first motor, a gear ring is meshingly connected to the outer side of the gear, fixed rods are fixedly connected on all four sides of the upper surface of the gear ring, and the top of the fixed rod is fixedly connected to the turntable.

[0008] As a preferred solution of the present invention, the turntable, support rod and shell are fixedly connected to form an integral structure, a connecting rod is fixedly connected to the shell, a connecting plate is fixedly provided on the top of the connecting rod, and pillars are fixedly provided on the connecting plate. The turntable, support rod, shell, connecting rod, connecting plate and pillars are fixedly connected to form an integral structure, and the connecting rods are evenly spaced on the connecting plate.

[0009] As a preferred solution of the present invention, the first connecting tube, the second connecting tube, the third connecting tube and the fourth connecting tube are nested from the inside to the outside, the outer walls of the first connecting tube, the second connecting tube, the third connecting tube and the fourth connecting tube are in contact with the inner wall of the annular groove, and the connection structure between the first connecting tube and the second connecting tube is the same as the connection structure between the third connecting tube and the fourth connecting tube.

[0010] As a preferred solution of the present invention, the adjustment assembly includes a first guide block fixedly connected to the bottom of the first connecting cylinder, a first screw is installed on the internal thread of the first guide block, a cylinder is arranged above the rotating block, a convex ring is fixedly connected to the outer side of the first guide block, a first rotating ring is rotatably connected to the outer side of the convex ring, a first guide rod is penetrated through the first rotating ring, and the first guide rod and the cylinder are fixedly connected.

[0011] As a preferred solution of the present invention, the first screw and the barrel are rotationally connected, a spring is fixedly arranged inside the first screw, a clamping block is fixedly connected to the spring, the outer wall of the protruding part of the clamping block on the first screw fits with the barrel, and a traction steel rope is fixedly connected between the clamping blocks on the first screw.

[0012] As a preferred solution of the present invention, the rotating block is made of rubber, the rotating block and the cylinder are in contact with each other, the rotating block is a truncated cone structure with a hollow interior, and the second motor and the support seat are slidably connected.

[0013] As a preferred solution of the present invention, the connecting assembly includes a second guide block fixedly connected to the bottom of the second connecting cylinder, the second guide block is internally threaded with a second screw, the second screw is fixedly connected to an outer cylinder, a second swivel is installed on the outer side of the outer cylinder, the outer sides of the second swivel and the first swivel are both provided with longitudinal convex patterns, and the first swivel is suitable for moving upward or downward with the first guide block when the first screw rotates.

[0014] A method for using a device capable of rapidly sorting rare blood cells comprises the following steps:

[0015] S1: When in use, a blood sample is injected into the interior of the housing, and the drive assembly drives the turntable to rotate above the support plate. When the housing rotates, the blood sample is gathered toward the arc-shaped inner wall of the housing under the action of centrifugal force, and blood cells with larger size and higher density are gathered toward the periphery of the inner wall of the housing, while cells with smaller size and lower density are located near the center of the inner wall of the housing;

[0016] S2: Close the cover plate on the housing, and drive the rotating block to rotate through the second motor. The rotating block drives the adjusting component to work. The adjusting component pushes the first connecting tube upward. After the first connecting tube moves upward to a certain extent, it drives the connecting component to work. When working, the connecting component automatically pushes the second connecting tube upward, and cooperates with the filter tube to separate cells of different sizes and densities.

[0017] S3: Before use, the volume inside the device can be adjusted according to the amount of blood to be separated. The first connecting tube and the second connecting tube can be driven to rise and fall by the adjusting component and the connecting component. The third connecting tube and the fourth connecting tube can be driven to rise and fall in the same way, thereby dividing the internal space of the shell.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] 1. By providing the liftable first connecting cylinder, the second connecting cylinder, the third connecting cylinder and the fourth connecting cylinder, when the amount of blood sample to be sorted is large, the first connecting cylinder, the second connecting cylinder, the third connecting cylinder and the fourth connecting cylinder can be stored so that the device has enough accommodation space during the centrifugal separation process, thereby preventing blood from splashing out of the shell. When the amount of blood sample is small, the connecting cylinders can be lifted one by one from the inside to the outside, thereby reducing the volume in the shell, so that the internal space of the device can be adaptively adjusted during the centrifugal filtration process, thereby solving the problem that the existing cell sorting device cannot adjust the size of the centrifugal sorting space according to the amount of blood during centrifugal filtration.

[0020] 2. Through the adjustment component and the connection component on the device, after the second motor is started, the second motor will use the friction between the rotating block and the cylinder to drive the cylinder to rotate, and the cylinder drives the screw to rotate through the clamping block. When the screw rotates, it will drive the first guide block and the first cylinder to slide upward. When the first guide block slides upward, it will drive the first rotating ring to move upward through the convex ring. When the first rotating ring moves upward until it abuts against the second rotating ring, it will drive the second rotating ring to rotate. The second rotating ring will drive the second screw to rotate, thereby driving the second guide block and the second connecting cylinder to move upward, so that the device can drive different cylinders to move upward one by one from the inside to the outside, thereby enhancing the convenience of the device when used.

[0021] 3. The device is provided with a first connecting cylinder, a second connecting cylinder, a third connecting cylinder and a fourth connecting cylinder having the same connecting structure. During the separation of the blood sample, centrifugal force can be used to make cells with larger size and higher density in the blood sample closer to the outer wall of the shell, while cells with smaller size and lower density are closer to the central axis of the shell. The connecting cylinders in four positions can be lifted during the continuous rotation of the shell, thereby realizing the function of sorting cells of different sizes and densities, which solves the problem that the existing sorting device cannot separate cells of different densities and sizes during centrifugal separation by using multiple separation structures. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the present invention will be described in detail below in combination with the accompanying drawings and detailed embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:

[0023] Figure 1 This is a schematic diagram of the overall structure of a device for rapidly sorting rare blood cells according to the present invention;

[0024] Figure 2 It is a schematic diagram of the internal structure of the support base of the present invention;

[0025] Figure 3 yes Figure 2 A magnified schematic diagram of the structure at center A;

[0026] Figure 4 yes Figure 2 A magnified schematic diagram of the structure at B in the middle;

[0027] Figure 5 It is a schematic diagram of the internal structure of the cylinder of the present invention;

[0028] Figure 6 yes Figure 5 A magnified schematic diagram of the structure at C in the middle;

[0029] Figure 7 It is a schematic diagram of the structure of the connecting rod and the connecting plate of the present invention;

[0030] Figure 8 It is a schematic diagram of the connection structure of the bracket and the lap ring of the present invention;

[0031] Fig. 9 It is a schematic diagram of the overall structure of the bracket of the present invention.

[0032] Figure numerals: 1, support seat; 2, support plate; 3, drive assembly; 301, first motor; 302, gear; 303, gear ring; 304, fixing rod; 4, turntable; 5, second motor; 6, ball; 7, support rod; 8, housing; 9, connecting rod; 10, connecting plate; 11, pillar; 12, first connecting cylinder; 13, second connecting cylinder; 14, third connecting cylinder; 15, fourth connecting cylinder; 16, adjustment assembly; 1601, first guide block; 1602, The first screw rod; 1603, the cylinder; 1604, the first rotating ring; 1605, the first guide rod; 1606, the convex ring; 17, the connecting assembly; 1701, the second guide block; 1702, the second screw rod; 1703, the outer cylinder; 1704, the second rotating ring; 18, the rotating block; 19, the clamping block; 20, the spring; 21, the traction rope; 22, the cover plate; 23, the rubber block; 24, the counterweight block; 25, the filter cylinder; 26, the annular groove; 27, the bracket; 28, the lap ring. DETAILED DESCRIPTION

[0033] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0034] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0035] Secondly, the present invention is described in detail with reference to schematic diagrams. When describing the embodiments of the present invention in detail, for the sake of convenience, the cross-sectional diagrams showing the device structure will not be partially enlarged according to the general scale, and the schematic diagrams are only examples, which should not limit the scope of protection of the present invention. In addition, in actual production, the three-dimensional dimensions of length, width and depth should be included.

[0036] In order to make the objectives, technical solutions and advantages of the present invention more clear, the embodiments of the present invention will be further described in detail below with reference to the accompanying drawings.

[0037] like Figure 1-Figure 9As shown, a device for rapidly sorting rare blood cells comprises a support base 1, on which a support disk 2 is fixedly arranged, a driving assembly 3 is installed in the support base 1, a turntable 4 is connected above the driving assembly 3, a support rod 7 is fixedly arranged above the turntable 4, a shell 8 is fixedly connected to the top of the support rod 7, a first connecting cylinder 12, a second connecting cylinder 13, a third connecting cylinder 14 and a fourth connecting cylinder 15 are arranged between the shell 8 and the turntable 4, the driving assembly 3 is used to drive the shell 8 to rotate, the first connecting cylinder 12, the second connecting cylinder 13, the third connecting cylinder 14 and the fourth connecting cylinder 15 in the shell 8 can not only lift the connecting cylinders at local positions before centrifugal separation of cells, so as to adjust the solvent in the device according to the amount of blood sample, but also can separate cells of different sizes and densities by lifting the first connecting cylinder 12, the second connecting cylinder 13, the third connecting cylinder 14 and the fourth connecting cylinder 15 during the centrifugal separation process, so as to realize the cell sorting function, an adjusting assembly 16 is arranged below the first connecting cylinder 12, the second connecting cylinder 13 A connection assembly 17 is provided below the housing 8, a second motor 5 is installed on the support seat 1, a rotating block 18 is connected to the output shaft of the second motor 5, a cover plate 22 is hinged on the side of the housing 8, a rubber block 23 and a counterweight block 24 are fixedly connected to the cover plate 22, the rubber block 23 can maintain a clamping state with the housing 8 after the cover plate 22 is closed, and the counterweight block 24 can continue to rotate through the housing 8 after the cover plate 22 is closed, and a filter cartridge 25 is installed on the housing 8, and a first connecting cylinder 12 and a second connecting cylinder 13 are provided on the filter cartridge 25. , an annular groove 26 through which the third connecting tube 14 and the fourth connecting tube 15 pass, a bracket 27 is fixedly arranged on the support seat 1, a lap ring 28 is installed on the bracket 27, the lap ring 28 and the adjusting component 16 are rotatably connected, the adjusting component 16 and the connecting component 17 on the device can first drive the first connecting tube 12 to rise and then drive the second connecting tube 13 to move upward and keep the first connecting tube 12 stationary, thereby enhancing the convenience of the device when used, and only a single driving device is needed to realize the function of lifting the connecting tubes one by one.

[0038] In this embodiment, the top of the support disk 2 is rotatably connected with ball bearings 6, which are evenly distributed along the circumference of the support disk 2. The central axes of the support seat 1, support disk 2, turntable 4 and outer shell 8 are collinear to ensure the overall stability of the device. The ball bearings 6 can reduce the resistance of the turntable 4 during rotation and support the turntable 4 at the same time.

[0039] In this embodiment, the driving component 3 includes a first motor 301 fixedly mounted on the support base 1, a gear 302 is fixedly connected to the output shaft of the first motor 301, a gear ring 303 is meshingly connected to the outer side of the gear 302, a fixing rod 304 is fixedly connected to the four sides of the upper surface of the gear ring 303, and the top of the fixing rod 304 is fixedly connected to the turntable 4. The gear 302 is driven to rotate by the first motor 301 on the device, and the gear 302 drives the gear ring 303 to rotate, thereby driving the turntable 4 to rotate through the fixing rod 304, so that the blood sample in the subsequent rotating device can be centrifuged and sorted.

[0040] In this embodiment, the turntable 4, the support rod 7 and the outer shell 8 are fixedly connected to form an integral structure, a connecting rod 9 is fixedly connected to the outer shell 8, a connecting plate 10 is fixedly provided on the top of the connecting rod 9, and a pillar 11 is fixedly provided on the connecting plate 10. The turntable 4, the support rod 7, the outer shell 8, the connecting rod 9, the connecting plate 10 and the pillar 11 are fixedly connected to form an integral structure, and the connecting rods 9 are evenly spaced on the connecting plate 10. The evenly spaced connecting rods 9 can connect the outer shell 8 with multiple segmented structures into a whole without affecting the normal lifting and lowering of the connecting tubes at various locations below the outer shell 8.

[0041] In this embodiment, the first connecting tube 12, the second connecting tube 13, the third connecting tube 14 and the fourth connecting tube 15 are nested from the inside to the outside, and the outer walls of the first connecting tube 12, the second connecting tube 13, the third connecting tube 14 and the fourth connecting tube 15 are in contact with the inner wall of the annular groove 26. The connection structure between the first connecting tube 12 and the second connecting tube 13 is the same as the connection structure between the third connecting tube 14 and the fourth connecting tube 15. The four nested connecting tubes enable the device to adjust its own volume to accommodate different amounts of blood samples.

[0042] In this embodiment, the adjustment component 16 includes a first guide block 1601 fixedly connected to the bottom of the first connecting cylinder 12, the first guide block 1601 is internally threaded with a first screw rod 1602, a cylinder body 1603 is arranged above the rotating block 18, the outer side of the first guide block 1601 is fixedly connected with a convex ring 1606, the outer side of the convex ring 1606 is rotatably connected with a first rotating ring 1604, a first guide rod 1605 is penetrated by the first rotating ring 1604, the first guide rod 1605 and the cylinder body 1603 are fixedly connected, when the cylinder body 1603 rotates, it will drive the first screw rod 1602 to rotate, thereby driving the first guide block 1601 to move upward, so as to subsequently adjust the position of the connecting cylinder in the device.

[0043] In this embodiment, the first screw 1602 and the cylinder 1603 are rotationally connected, a spring 20 is fixedly provided inside the first screw 1602, a block 19 is fixedly connected to the spring 20, the outer wall of the protruding part of the block 19 on the first screw 1602 fits with the cylinder 1603, a traction steel rope 21 is fixedly connected between the blocks 19 on the first screw 1602, when the cylinder 1603 rotates, the first screw 1602 is driven to rotate through the block 19, when the rotation resistance of the first screw 1602 is too large, the cylinder 1603 will slide on the first screw 1602, so that the cylinder 1603 on the device continues to rotate.

[0044] In this embodiment, the rotating block 18 is made of rubber material, and the rotating block 18 and the cylinder 1603 are in contact with each other. The rotating block 18 is an internal hollow conical structure. The second motor 5 and the support seat 1 are slidingly connected. After the rotating block 18 made of rubber material is tightly pressed against the cylinder 1603, the cylinder 1603 can rotate synchronously with the rotating block 18. The internal hollow rotating block 18 will deform after being squeezed, so that the position of the rotating block 18 can be adjusted later.

[0045] In this embodiment, the connection assembly 17 includes a second guide block 1701 fixedly connected to the bottom of the second connecting tube 13, the second guide block 1701 is internally threaded with a second screw 1702, the second screw 1702 is fixedly connected to an outer tube 1703, a second rotating ring 1704 is installed on the outer side of the outer tube 1703, the outer sides of the second rotating ring 1704 and the outer sides of the first rotating ring 1604 are both provided with longitudinal convex grooves, the first rotating ring 1604 is suitable for moving upward or downward with the first guide block 1601 when the first screw 1602 rotates, when the first guide block 1601 moves upward, it will drive the first rotating ring 1604 to move upward, so that the second rotating ring 1704 and the outer tube 1703 can be driven to rotate after the first rotating ring 1604 and the second rotating ring 1704 are docked, so that the second screw 1702 drives the second guide block 1701 and the second connecting tube 13 to move upward.

[0046] It should be noted that the present invention is a device for rapidly sorting rare blood cells and a method for using the same. First, Figure 1-Figure 7As shown, when the device is in use, first inject the blood sample into the housing 8, and the cover plate 22 is clamped and installed on the housing 8 through the rubber block 23. The counterweight block 24 can prevent the cover plate 22 from being opened during the centrifugal separation process. The first motor 301 on the driving assembly 3 drives the gear 302 to rotate, and the gear 302 drives the gear ring 303 to rotate, thereby driving the turntable 4 to rotate through the fixed rod 304. The turntable 4 rotates on the ball 6 on the support plate 2 to reduce the resistance of the turntable 4 to rotate, so that the turntable 4, the support rod 7 and the housing 8 rotate as a whole, and the blood sample in the rotating device is centrifuged and sorted. When the housing 8 rotates, the blood sample will gather to the arc-shaped inner wall of the housing 8 under the action of centrifugal force. The blood cells with larger size and higher density will gather to the periphery of the inner wall of the housing 8, and the cells with smaller size and lower density will be located near the center of the inner wall of the housing 8. Close the cover plate 22 on the housing 8, and drive the rotating block 18 to rotate through the second motor 5, and the rotating block 18 drives the adjustment assembly 16 to work. The friction between the rotating block 18 and the cylinder 1603 is used to drive the cylinder 1603 to rotate. The cylinder 1603 drives the first screw 1602 to rotate through the clamping block 19. When the first screw 1602 rotates, it drives the first guide block 1601 to move upward in the turntable 4, so that the first cylinder 1603 slides upward. When the first guide block 1601 slides upward, it drives the first rotating ring 1604 to move upward through the convex ring 1606. When the first rotating ring 1604 moves upward until it abuts against the second rotating ring 1704, since the outer sides of the first rotating ring 1604 and the second rotating ring 1704 are both provided with Longitudinal convex grooves, so the first rotating ring 1604 will drive the second rotating ring 1704 to rotate, and the second rotating ring 1704 will drive the second screw 1702 to rotate, thereby driving the second guide block 1701 and the second connecting cylinder 13 to move upward. When the first screw 1602 cannot rotate further, the cylinder 1603 will slide on the outside of the first screw 1602, the block 19 will be intermittently squeezed, and the spring 20 on the outside of the traction rope 21 will be intermittently compressed, so that the first screw 1602 remains stationary, and the cylinder 1603 continues to rotate and drives the second rotating ring 1704 to rotate continuously through the first rotating ring 1604.

[0047] like Figure 2-Figure 9 As shown, the first connecting tube 12 is pushed upward by the adjusting component 16. After the first connecting tube 12 moves upward to a certain extent, it will drive the connecting component 17 to work. When working, the connecting component 17 will automatically push the second connecting tube 13 upward. Since the connection structure between the first connecting tube 12 and the second connecting tube 13 is the same as the connection structure between the third connecting tube 14 and the fourth connecting tube 15, the third connecting tube 14 and the fourth connecting tube 15 can be progressively moved upward in the same way, thereby separating the space in the outer shell 8, and the filter tube 25 can be used to separate cells of different sizes and densities.

[0048] Before use, the volume inside the device can be adjusted according to the amount of blood to be separated. The first connecting cylinder 12 and the second connecting cylinder 13 can be driven to rise and fall by the adjusting component 16 and the connecting component 17. The third connecting cylinder 14 and the fourth connecting cylinder 15 can be driven to rise and fall in the same way, thereby dividing the internal space of the outer shell 8. When the cylinder body 1603 and the outer cylinder 1703 rotate, the cylinder body 1603 and the outer cylinder 1703 can be supported by the lap ring 28 on the bracket 27. Before use, the device can adapt to different blood sample volumes for cell sorting by pre-dividing the space inside the outer shell 8.

[0049] Although the present invention has been described above with reference to the embodiments, various modifications may be made thereto and parts thereof may be replaced by equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the various features in the embodiments disclosed in the present invention may be used in combination with each other in any manner, and the fact that these combinations are not exhaustively described in this specification is only for the sake of omitting space and saving resources. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A device for rapidly sorting rare blood cells, comprising a support base (1), characterized in that: A support disc (2) is fixedly arranged on the support seat (1), a driving assembly (3) is installed in the support seat (1), a turntable (4) is connected above the driving assembly (3), a support rod (7) is fixedly arranged above the turntable (4), a housing (8) is fixedly connected to the top of the support rod (7), a first connecting tube (12), a second connecting tube (13), a third connecting tube (14) and a fourth connecting tube (15) are arranged between the housing (8) and the turntable (4), an adjustment assembly (16) is arranged below the first connecting tube (12), a connection assembly (17) is arranged below the second connecting tube (13), a second connecting tube (14) and a fourth connecting tube (15) are arranged on the support seat (1). The motor (5) is provided with a rotating block (18) connected to the output shaft of the second motor (5); a cover plate (22) is hingedly connected to the side of the housing (8); a rubber block (23) and a counterweight (24) are fixedly connected to the cover plate (22); a filter cartridge (25) is installed on the housing (8); an annular groove (26) is provided on the filter cartridge (25) for the first connecting cartridge (12), the second connecting cartridge (13), the third connecting cartridge (14) and the fourth connecting cartridge (15) to pass through; a bracket (27) is fixedly provided on the support seat (1); a lap ring (28) is installed on the bracket (27); and the lap ring (28) is rotatably connected to the adjustment component (16).

2. The device for rapidly sorting rare blood cells according to claim 1, characterized in that: The top of the support disk (2) is rotatably connected with balls (6), and the balls (6) are evenly distributed along the circumference of the support disk (2). The central axes of the support seat (1), the support disk (2), the rotating disk (4) and the outer shell (8) are collinear.

3. The device for rapidly sorting rare blood cells according to claim 1, characterized in that: The driving assembly (3) comprises a first motor (301) fixedly mounted on the support seat (1); a gear (302) is fixedly connected to the output shaft of the first motor (301); a gear ring (303) is meshingly connected to the outer side of the gear (302); fixed rods (304) are fixedly connected to the four sides of the upper surface of the gear ring (303); and the top of the fixed rod (304) is fixedly connected to the turntable (4).

4. The device for rapidly sorting rare blood cells according to claim 1, characterized in that: The rotating disk (4), the supporting rod (7) and the outer shell (8) are fixedly connected to form an integral structure; a connecting rod (9) is fixedly connected to the outer shell (8); a connecting plate (10) is fixedly arranged on the top of the connecting rod (9); a pillar (11) is fixedly arranged on the connecting plate (10); the rotating disk (4), the supporting rod (7), the outer shell (8), the connecting rod (9), the connecting plate (10) and the pillar (11) are fixedly connected to form an integral structure; and the connecting rods (9) are evenly spaced on the connecting plate (10).

5. The device for rapidly sorting rare blood cells according to claim 1, characterized in that: The first connecting tube (12), the second connecting tube (13), the third connecting tube (14) and the fourth connecting tube (15) are nested and distributed from the inside to the outside, and the outer walls of the first connecting tube (12), the second connecting tube (13), the third connecting tube (14) and the fourth connecting tube (15) are in contact with the inner wall of the annular groove (26), and the connection structure between the first connecting tube (12) and the second connecting tube (13) is the same as the connection structure between the third connecting tube (14) and the fourth connecting tube (15).

6. The device for rapidly sorting rare blood cells according to claim 1, characterized in that: The adjustment assembly (16) comprises a first guide block (1601) fixedly connected to the lower part of the first connecting cylinder (12); a first screw rod (1602) is installed on the inner thread of the first guide block (1601); a cylinder body (1603) is arranged above the rotating block (18); a convex ring (1606) is fixedly connected to the outer side of the first guide block (1601); a first rotating ring (1604) is rotatably connected to the outer side of the convex ring (1606); a first guide rod (1605) is arranged through the first rotating ring (1604); and the first guide rod (1605) and the cylinder body (1603) are fixedly connected.

7. The device for rapidly sorting rare blood cells according to claim 6, characterized in that: The first screw rod (1602) and the cylinder (1603) are rotationally connected, a spring (20) is fixedly arranged inside the first screw rod (1602), a clamping block (19) is fixedly connected to the spring (20), the outer wall of the protruding part of the clamping block (19) on the first screw rod (1602) and the cylinder (1603) are in contact with each other, and a traction steel rope (21) is fixedly connected between the clamping blocks (19) on the first screw rod (1602).

8. The device for rapidly sorting rare blood cells according to claim 7, characterized in that: The rotating block (18) is made of rubber material. The rotating block (18) and the cylinder (1603) are in contact with each other. The rotating block (18) is a truncated cone structure with a hollow interior. The second motor (5) and the support seat (1) are in sliding connection.

9. The device for rapidly sorting rare blood cells according to claim 7, characterized in that: The connection assembly (17) comprises a second guide block (1701) fixedly connected to the lower side of the second connecting tube (13); the second guide block (1701) is internally threadedly mounted with a second screw rod (1702); the second screw rod (1702) is fixedly connected with an outer tube (1703); a second rotating ring (1704) is mounted on the outer side of the outer tube (1703); the outer sides of the second rotating ring (1704) and the outer sides of the first rotating ring (1604) are both provided with longitudinal convex grooves; the first rotating ring (1604) is adapted to move upward or downward along with the first guide block (1601) when the first screw rod (1602) rotates.

10. A method for using a device capable of rapidly sorting rare blood cells, using the device capable of rapidly sorting rare blood cells as claimed in claim 1, characterized in that: The following steps are involved: S1: When in use, a blood sample is injected into the interior of the housing (8), and the drive assembly (3) drives the turntable (4) to rotate above the support plate (2). When the housing (8) rotates, the blood sample is gathered toward the arc-shaped inner wall of the housing (8) under the action of centrifugal force, and blood cells with larger size and higher density are gathered toward the periphery of the inner wall of the housing (8), while cells with smaller size and lower density are located near the center of the inner wall of the housing (8); S2: closing the cover plate (22) on the housing (8), driving the rotating block (18) to rotate through the second motor (5), the rotating block (18) driving the adjusting component (16) to work, the adjusting component (16) pushing the first connecting tube (12) upwards, after the first connecting tube (12) moves upwards to a certain extent, it drives the connecting component (17) to work, and the connecting component (17) automatically pushes the second connecting tube (13) upwards when working, and cooperates with the filter tube (25) to separate cells of different sizes and densities; S3: Before use, the volume of the device can be adjusted according to the amount of blood to be separated, and the first connecting tube (12) and the second connecting tube (13) can be driven to rise and fall by using the adjusting component (16) and the connecting component (17). The third connecting tube (14) and the fourth connecting tube (15) can be driven to rise and fall in the same way, thereby dividing the internal space of the shell (8).

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