Self-mixing circulating type ventilation fermentation tank

Abstract

The invention discloses a self-mixing circulation type ventilation fermentation tank, and relates to the technical field of fermentation tanks, the self-mixing circulation type ventilation fermentation tank comprises a tank body, a circulation cylinder, an annular distribution pipe, an air branch pipe, an air main pipe and a three-phase mixer, the circulation cylinder is fixed in the tank body, and the upper end and the lower end of the circulation cylinder are opened; a plurality of annular distribution pipes with different inner diameters are fixed at the bottom of the tank body, the annular distribution pipes are distributed on the outer side of the circulating cylinder, the annular distribution pipes are communicated with the first ends of the air branch pipes, the second ends of the air branch pipes are communicated with an air outlet of the air main pipe, and the air main pipe is communicated with the circulating cylinder. An air inlet of the main air pipe penetrates through the side wall of the tank body and is connected with an air source, a plurality of three-phase mixers are arranged on each annular distribution pipe, and ejection ports of the three-phase mixers are vertically upward. Self-mixing circulation of fermentation liquor in the tank body is realized by utilizing directional flowing of gas, liquid and solid phases in the tank body, an additional stirring device does not need to be arranged, and energy consumption is reduced.

Description

Technical Field

[0001] The invention relates to the technical field of fermentation tanks, in particular to a self-mixing circulation type ventilation fermentation tank. Background Art

[0002] Almost all domestic fermentation industries such as antibiotics, vitamins, amino acids, and organic acids use universal ventilated stirred reactor technology for industrial product production. Since North China Pharmaceutical started industrial production of penicillin in 1958, there has been no major breakthrough in fermentation equipment for more than 60 years. The fermentation process has always been plagued by poor engineering conditions, large energy waste, high energy consumption, and low ventilation oxygen utilization.

[0003] In the aerobic fermentation industry, energy consumption (air oxygen supply, steam sterilization, stirring power consumption, circulating water cooling) accounts for 20%-30% of the total product cost, of which stirring for fermentation accounts for 20%-50% of the total energy consumption. It can be seen that the stirring device accounts for a large proportion of the total energy consumption during the fermentation process. Therefore, there is an urgent need for a fermentation tank that can solve the above problems in the market. Summary of the invention

[0004] The purpose of the present invention is to provide a self-mixing circulating ventilated fermenter to solve the above-mentioned problems existing in the prior art. It realizes self-mixing of the fermentation liquid through a circulating structure, does not require a stirring device, and greatly reduces energy consumption.

[0005] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0006] A self-mixing circulation ventilated fermentation tank of the present invention comprises a tank body, a circulation cylinder, an annular distribution pipe, an air branch pipe, an air main pipe and a three-phase mixer, wherein the circulation cylinder is fixed in the tank body, the upper and lower ends of the circulation cylinder are open, a plurality of annular distribution pipes with different inner diameters are fixed to the bottom of the tank body, and the plurality of annular distribution pipes are distributed on the outside of the circulation cylinder, the annular distribution pipe is connected to the first end of the air branch pipe, the second end of the air branch pipe is connected to the air outlet of the air main pipe, the air inlet of the air main pipe passes through the side wall of the tank body and is connected to an air source, and a plurality of the three-phase mixers are provided on each of the annular distribution pipes, and the spray outlet of the three-phase mixer is vertically facing upward.

[0007] Preferably, the circulation ratio of the circulation drum inside and outside is: (cross-sectional area of ​​the tank body - cross-sectional area of ​​the circulation drum) / cross-sectional area of ​​the circulation drum, and the ratio is (3-4) / 1.

[0008] Preferably, the number of the air branches is the same as the number of the annular distribution pipes, and they are connected one-to-one.

[0009] Preferably, the number of the annular distribution pipes is 2-3.

[0010] Preferably, the lower end of the circulation drum is fixed to the upper ends of a plurality of first supports, and the lower ends of the first supports are fixed to the bottom of the tank body.

[0011] Preferably, the first support is a T-shaped steel structure, a groove is provided on one surface of the first support, and the lower end of the circulation drum is inserted into the groove.

[0012] Preferably, the annular distribution pipe is fixed on a plurality of second supports, and one end of the second support is fixed on the inner wall of the tank body.

[0013] Preferably, the second support is a T-shaped steel structure, and a plurality of fixing rings are provided on one surface of the second support. The number of fixing rings of each second support is the same as the number of the annular distribution pipes, and the annular distribution pipes pass through the corresponding fixing rings.

[0014] Compared with the prior art, the beneficial technical effects of the present invention are:

[0015] The self-mixing circulation type ventilation fermentation tank of the present invention adopts a smaller-sized circulation cylinder, which can fully adapt to the structural characteristics of various types of fermentation tanks, and directional circulation from the outside of the cylinder to the inside of the cylinder, which can not only meet the needs of gas-liquid-solid three-phase circulation mixing, but also meet the needs of tank operation; at the same time, the self-mixing of the fermentation liquid is achieved through the circulation structure, and no stirring device is required, which greatly reduces energy consumption, and the fermentation engineering conditions are better than those of the general stirring and ventilation fermentation tank. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 It is a structural schematic diagram of the self-mixing circulation ventilation fermenter of the present invention;

[0018] Figure 2 It is a schematic diagram of the partial structure of the bottom of the tank body of the self-mixing circulation ventilation fermentation tank of the present invention;

[0019] Figure 3 It is a schematic diagram of the top view of the structure inside the tank body of the self-mixing circulation type ventilation fermentation tank of the present invention;

[0020] Figure 4 It is a schematic structural diagram of the first support of the self-mixing circulation type ventilation fermentation tank of the present invention;

[0021] Figure 5It is a schematic structural diagram of the second support of the self-mixing circulation ventilation fermenter of the present invention.

[0022] Explanation of the reference numerals: 1-tank body; 2-cooling coil; 3-circulation cylinder; 4-air main pipe; 5-three-phase mixer; 6-annular distribution pipe; 7-air branch pipe; 8-first support; 9-second support; 100-self-mixing circulation ventilation fermenter. DETAILED DESCRIPTION

[0023] Embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0024] In the description of the present invention, it should be understood that the terms "length", "width", "inside", "outside" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.

[0025] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0026] The technical solution provided by the embodiments of the present invention is described in detail below with reference to the accompanying drawings.

[0027] like Figures 1 to 5As shown, the self-mixing circulation type ventilation fermentation tank 100 of this embodiment includes a tank body 1, and a cooling coil 2 is arranged in the tank body 1. The cooling coil 2 is provided with multiple groups, and is wound multiple circles along the inner wall of the fermentation tank body 1, and is fixed inside the tank body 1. The cold water inlet and the cold water outlet of the cooling coil 2 both penetrate the side wall of the tank body 1. Circulating cooling water is passed into the cooling coil 2 to take away the fermentation heat of the biological reaction process. A circulation cylinder 3 is fixed in the tank body 1, and a circulation cylinder 3 of a smaller size is used. The purpose of this is to form a larger cylinder outside the cylinder flow ratio, and the cylinder outside the cylinder flow ratio is: (cross-sectional area of ​​the tank body 1-cross-sectional area of ​​the circulation cylinder 3) / cross-sectional area of ​​the circulation cylinder 3, and the specific ratio is (3-4) / 1. The upper and lower ends of the circulation cylinder 3 are open.

[0028] like Figure 2 , Figure 3 As shown, a plurality of annular distribution pipes 6 with different inner diameters are fixed to the bottom of the tank body 1, and the plurality of annular distribution pipes 6 are distributed outside the circulation tube 3, and the circulation tube 3 is located in the inner circle of the annular distribution pipes 6, and the plurality of annular distribution pipes 6 are all connected to the air outlet of the air main pipe 4. The air inlet of the air main pipe 4 passes through the side wall of the tank body 1, and the air inlet of the air main pipe 4 is connected to an air source. A plurality of three-phase mixers 5 are arranged on each annular distribution pipe 6, and the structure of the three-phase mixer 5 is the same as that of the existing three-phase mixer 5, and the size of the three-phase mixer 5 is appropriately adjusted according to the different sizes of the tank body 1.

[0029] When the self-mixing circulation ventilated fermentation tank 100 of this embodiment is in use, air is introduced into the air main pipe 4, and is distributed into the annular distribution pipe 6 outside the circulation cylinder 3 under pressure conditions. The pressure air is evenly distributed to multiple special three-phase mixers 5 in the pressure equalization system of the annular distribution pipe 6. The pressure air realizes the conversion of static pressure energy into kinetic energy from the air nozzle. According to the principle of Bernoulli's equation, under the suction effect of high-speed gas flow, liquid and solid enter the mixing tube of the three-phase mixer 5, and the gas, liquid and solid are fully sheared and mixed into a uniform body in the three-phase mixer 5, and move upward outside the circulation cylinder 3; in the fluid Under the continuous characteristics, the active driving force of the density difference between the inside and outside and the passive driving force of the air kinetic energy, the mixed liquid moves upward along the outside of the circulation tube 3 to the top of the tank body 1, and quickly bends into the inside of the circulation tube 3 to accelerate the reverse movement, so that the fermentation liquid inside the circulation tube 3 carries the gas and solid to move rapidly in the reverse direction. With a large outside-to-inside flow ratio, the inside of the circulation tube 3 carries a large number of bubbles and solids in the reverse direction at high speed to form a complete cycle; the reverse impulse momentum of the high-speed mixed liquid in the circulation tube 3 pushes the fermentation liquid retained at the bottom of the tank to move to the outside of the circulation tube 3, and merges into the overall cycle with the upward carrying effect of the external bubbles. In this way, the whole tank realizes the "three transmission and one reverse" fermentation engineering conditions of directional, no retention area, ultra-high gas content, and high-speed circulation mixing, which fully meets the ventilation and fermentation conditions of various products in the fermentation tank.

[0030] In this embodiment, the nozzle of the three-phase mixer 5 faces upward, that is, upward is positive movement. Those skilled in the art can also set the nozzle of the three-phase mixer 5 to face downward according to actual needs. The working principle is the same as the above principle, but the direction is opposite.

[0031] As for the specific number of the annular distribution pipes 6, in the present embodiment, the number of the annular distribution pipes 6 is 2-3, and each annular distribution pipe 6 is provided with a plurality of three-phase mixers 5, which expands the adaptability range of the tank body 1 to meet various fermentation products. The gas-liquid-solid mixture diffuses upward along the outside of the circulation tube 3, and the gas-liquid specific surface area is maximized in the high mass transfer area outside the circulation tube 3, thereby achieving an ultra-high volumetric oxygen transfer coefficient, which fully meets the demand of the bacteria's own huge specific surface area for environmental factors and nutrients.

[0032] Regarding the connection relationship between the annular distribution pipe 6 and the main air pipe 4, in this embodiment, the annular distribution pipe 6 is connected to the first end of the air branch pipe 7, and the second end of the air branch pipe 7 is connected to the main air pipe 4. The number of the air branch pipes 7 is the same as the number of the annular distribution pipes 6, and one annular distribution pipe 6 is connected to one air branch pipe 7.

[0033] In order to fix the circulation drum 3, in this embodiment, the lower end of the circulation drum 3 is fixed to the upper ends of several first supports 8, and the lower ends of the first supports 8 are fixed to the bottom of the tank body 1. There can be four or five first supports 8.

[0034] For the specific structure of the first support 8, Figure 4 As shown, the first support 8 is a T-shaped steel structure. A groove is provided on one surface of the first support 8, and the lower end of the circulation drum 3 is inserted into the groove.

[0035] In order to fix the annular distribution pipe 6, the annular distribution pipe 6 is fixed on a plurality of second supports 9, and the plurality of second supports 9 are evenly distributed on the annular distribution pipe 6. One second support 9 can simultaneously support a plurality of annular distribution pipes 6, and one end of the second support 9 is fixed on the inner wall of the tank body 1. Furthermore, the annular distribution pipe 6 should be distributed obliquely, and the annular distribution pipe 6 is provided with a plurality of discharge holes to facilitate the pouring out of the material in the annular distribution pipe 6.

[0036] For the specific structure of the second support 9, Figure 5 As shown, the second support 9 is a T-shaped steel structure, and a plurality of fixing rings are provided on one surface of the second support 9 . The number of fixing rings of each second support 9 is the same as the number of annular distribution pipes 6 , and one annular distribution pipe 6 passes through one fixing ring on one second support 9 .

[0037] Under the effects of the density difference inside and outside the circulation tube 3, the driving force of the kinetic energy of air, the continuity characteristics of the fluid, etc., a circulation flow is formed with the outside of the circulation tube 3 being upward and the inside being downward. The large outside-to-inside flow ratio structure makes the downward flow velocity inside the circulation tube 3 large enough, pulling a certain proportion of high-gas-content liquid and solid to move downward. The high-speed downward impulse momentum pushes the fermentation liquid retained at the bottom of the fermentation tank to the outside of the tube and, accompanied by the lifting effect of the rising bubbles, enters the external high mass transfer area, ensuring that there are no dead corners and retention areas in the entire tank.

[0038] According to the characteristics of the bacteria producing each product, variable shear stress and variable oxygen transfer rate are achieved, fully satisfying the periodic change characteristics of each bacterial genus.

[0039] The self-mixing circulating ventilated fermenter of the present invention realizes self-mixing of the fermentation liquid through a circulating structure, does not require a stirring device, greatly reduces energy consumption, and realizes fermentation engineering characteristic parameters such as cycle time, circulating liquid velocity, mixing time, gas content, volume oxygen transfer coefficient, PecLet number, gas-liquid-solid three-phase uniformity, dissolved oxygen rate, etc., which are all superior to those of traditional ventilated mechanical stirring fermentation reactors.

[0040] The embodiments described above are only descriptions of the preferred modes of the present invention, and are not intended to limit the scope of the present invention. Without departing from the design spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by ordinary technicians in this field should all fall within the protection scope determined by the claims of the present invention.

Claims

1. A self-mixing circulation ventilation fermenter, characterized in that: It includes a tank body, a circulation cylinder, an annular distribution pipe, an air branch pipe, an air main pipe and a three-phase mixer. The circulation cylinder is fixed in the tank body, and the upper and lower ends of the circulation cylinder are open. A plurality of annular distribution pipes with different inner diameters are fixed to the bottom of the tank body. The plurality of annular distribution pipes are distributed on the outside of the circulation cylinder. The annular distribution pipe is connected to the first end of the air branch pipe, and the second end of the air branch pipe is connected to the air outlet of the air main pipe. The air inlet of the air main pipe passes through the side wall of the tank body and is connected to an air source. Each of the annular distribution pipes is provided with a plurality of three-phase mixers, and the spray outlet of the three-phase mixer is vertically facing upward.

2. The self-mixing circulation aeration fermenter according to claim 1, characterized in that: The circulation ratio between the outside and inside of the circulation drum is: (the cross-sectional area of ​​the tank body-the cross-sectional area of ​​the circulation drum) / the cross-sectional area of ​​the circulation drum, and the ratio is (3-4) / 1.

3. The self-mixing circulation aeration fermenter according to claim 1, characterized in that: The number of the air branches is the same as the number of the annular distribution pipes, and they are connected one-to-one.

4. The self-mixing circulation aeration fermenter according to claim 1, characterized in that: The number of the annular distribution pipes is 2-3.

5. The self-mixing circulation aeration fermenter according to claim 1, characterized in that: The lower end of the circulation drum is fixed to the upper ends of a plurality of first supports, and the lower end of the first supports is fixed to the bottom of the tank body.

6. The self-mixing circulation aeration fermenter according to claim 5, characterized in that: The first support is a T-shaped steel structure. A groove is provided on one surface of the first support, and the lower end of the circulation drum is inserted into the groove.

7. The self-mixing circulation aeration fermenter according to any one of claims 1 to 6, characterized in that: The annular distribution pipe is fixed on a plurality of second supports, and one end of the second support is fixed on the inner wall of the tank body.

8. The self-mixing circulation aeration fermenter according to claim 7, characterized in that: The second support is a T-shaped steel structure. A plurality of fixing rings are provided on one surface of the second support. The number of fixing rings of each second support is the same as the number of the annular distribution pipes. The annular distribution pipes pass through the corresponding fixing rings.

Images