Preparation method of probenecid solution for poultry

By adding co-solvents, stabilizers and other ingredients to the probenecid solution for avian and using specific preparation methods, the problems of low solubility of the existing preparations and complex preparation process are solved, and efficient and stable probenecid solution preparation is achieved, which is suitable for long-term storage and oral use, significantly improving the treatment effect of avian gout disease.

CN119523892APending Publication Date: 2025-02-28HEBEI KEXING PHARMA
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Patent Information

Application Number
CN202411752398.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2025-02-28

AI Technical Summary

Technical Problem

The existing probenecid veterinary drug preparations have low solubility, complex preparation process, high cost, and are not suitable for long-term storage and oral use, making it difficult to effectively treat avian gout.

Method used

By adding components such as cosolvents, stabilizers, complexing agents, and using specific addition order and dissolution temperature, a probenecid solution for avians is prepared to improve the solubility of probenecid and the stability of the drug solution.

Benefits of technology

The high solubility and stability of probenecid solution is achieved, the production cost is reduced, the long-term storage is suitable for poultry, and the effect of treating avian gout is significantly improved.

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Abstract

The invention belongs to the technical field of veterinary drugs for poultry, and discloses a preparation method of a probenecid solution for poultry, and the probenecid solution prepared by adding raw materials such as probenecid, a cosolvent, an antioxidant, a complexing agent, a stabilizer and the like according to a specific adding sequence and carrying out a specific temperature dissolving and filtering process has the characteristics that the pH value is still stable after long-term storage, and the probenecid solution has the characteristics of high stability, high stability and the like. And when the water is used for drinking water for poultry, the dosage is accurate, the administration is easy, the safety is good, and the use is convenient. The probenecid solution solves the problems that the existing probenecid solution is poor in stability and inconvenient to orally take by poultry by adjusting the proportion of the raw material components and specifically adding specific auxiliary substances. The product disclosed by the invention is suitable for preparing the poultry anti-gout medicine.
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Citation Information

Patent Citations

  • Probenecid-based drug delivery system, preparation method and application

    CN118717679A