Traditional Chinese medicine composition for treating leukorrheal diseases and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating leukorrheal diseases and a preparation method of the traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicines for treating gynecological diseases. The traditional Chinese medicine composition is prepared from the following raw material medicines: 20 to 35g of rhizoma atractylodis macrocephalae stir-fried with bran, 20 to 35g of rhizoma dioscoreae stir-fried with bran, 3 to 9g of ginseng, 10 to 20g of parched white paeony root, 6 to 15g of salted semen plantaginis, 6 to 12g of rhizoma atractylodis stir-fried with bran, 10 to 20g of pericarpium citri reticulatae, 10 to 20g of charred schizonepeta, 10 to 20g of radix bupleuri, 10 to 30g of cuttlebone, 10 to 30g of hairyvein agrimony, 5 to 15g of radix sophorae flavescentis, 5 to 15g of fructus cnidii, 5 to 15g of fructus kochiae, 0.6 to 1.5 g of alumen, 15 to 25g of rhizoma smilacis glabrae and 2 to 10g of liquorice, so that the traditional Chinese medicine composition achieves the effects of and the preparation method is simple and convenient, low in price, economical and practical, free of toxic and side effects and good in drug compliance.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine for treating gynecological diseases, and in particular to a traditional Chinese medicine composition for treating leucorrhea and a preparation method thereof. Background Art

[0002] Physiological leucorrhea is a kind of vaginal fluid in women's bodies. It is a mixture of vaginal mucosal exudate, cervical canal and endometrial gland secretions. It is a transparent mucus without special smell that moisturizes the vulva and keeps the vagina lubricated. Under normal circumstances, the amount, color, quality and smell of leucorrhea change with the changes in women's menstrual cycle.

[0003] Leucorrhea refers to female vaginal discharge, which is thick like mucus, or dense or thin, and has five colors: red, green, yellow, white, and black. It has an abnormal odor or is accompanied by systemic or local symptoms. Among them, leucorrhea is the most common, the most common, and the most easily ignored. According to traditional Chinese medicine theory, "leucorrhea" is named after the belt, and the main pathogenesis is the instability of the conception meridian and the failure of the belt meridian, which leads to this disease. In modern life, women face the pressure of a fast pace of life and high work intensity, and are often accompanied by irregular eating and rest such as liking cold drinks, overeating, physical overdraft, and mental tension.

[0004] Traditional Chinese medicine believes that eating fatty and sweet food will increase the burden on the spleen and stomach, leading to spleen and stomach weakness and inability to transport and transform water and dampness. Excessive worry, emotional discomfort, and mental tension will lead to liver depression and qi stagnation, spleen and earth damage, qi disorder, and endogenous water and dampness, all of which are the main causes of leukorrhea. According to surveys and studies, leukorrhea has the highest incidence rate among gynecological diseases, especially in married women, reaching more than 90%. Although Western medicine can achieve certain therapeutic effects in the treatment of leukorrhea, there are problems such as easy recurrence, drug side effects, and drug resistance. In addition, repeated attacks of leukorrhea that are not cured for a long time will gradually develop into vaginitis, cervicitis, pelvic inflammatory disease, endocrine dysfunction, irregular menstruation, infertility and other diseases, causing physical and mental distress to women. Summary of the invention

[0005] The present invention provides a Chinese medicine composition for treating leucorrhea and a preparation method thereof, so as to solve the technical problems of easy recurrence, drug side effects and drug resistance in the prior art of treating leucorrhea with traditional Chinese and western medicine, and achieve the technical effect that the Chinese medicine composition has a classic formula, good therapeutic effect and rapid onset, and the preparation method is simple, low-priced, economical and practical, has no toxic side effects and good drug compliance, thereby improving the cure rate of leucorrhea and reducing the recurrence rate.

[0006] In the first aspect, the present invention provides a traditional Chinese medicine composition for treating leukorrhea, which comprises the following raw materials by weight: 20-35g of stir-fried Atractylodes macrocephala, 20-35g of stir-fried Chinese yam, 3-9g of ginseng, 10-20g of stir-fried white peony root, 6-15g of salt plantain seed, 6-12g of stir-fried Atractylodes lancea, 10-20g of dried tangerine peel, 10-20g of schizonepeta charcoal, 10-20g of bupleurum, 10-20g of cuttlebone, 10-30g of agrimony, 5-15g of Sophora flavescens, 5-15g of Cnidium monnieri, 5-15g of Kochia scoparia, 0.6-1.5g of alum, 15-25g of Smilax glabra, and 2-10g of licorice.

[0007] In a second aspect, the present invention also provides a method for preparing a Chinese medicine composition for treating leukorrhea, which is used to prepare the aforementioned Chinese medicine composition for treating leukorrhea, and the method comprises: step 1: weighing the raw materials for preparing the Chinese medicine composition according to a preset formula, wherein the raw materials include fried Atractylodes macrocephala, fried yam, ginseng, fried white peony root, salt plantain seed, fried Atractylodes lancea, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and licorice; step 2: mixing the raw materials in step 1 evenly to obtain a first mixed drug and a first total drug. dosage; step 3: adding cold water to the first mixed medicine according to the first times of the first total amount of medicine, and soaking for a first preset time; step 4: heating and boiling the first mixed medicine after soaking in step 3, decocting for a second preset time and filtering to obtain a first medicinal residue and a first decoction; step 5: adding a second times amount of water to the first medicinal residue, continuing to decoct for a third preset time, filtering to obtain a second decoction; step 6: mixing the first decoction and the second decoction, and concentrating to a first concentrated amount to obtain a Chinese medicine decoction.

[0008] Preferably, in step 1, the salt plantain seeds are individually packed in gauze bags.

[0009] Preferably, in step 3, the first preset time is 2 hours.

[0010] Preferably, the first amount is 4 to 5 times, and the second amount is 2 to 3 times, or the first amount is 8 to 10 times, and the second amount is 4 to 5 times.

[0011] Preferably, in step 4, the second preset time is 30 minutes.

[0012] Preferably, in step 5, the third preset time is 20 minutes.

[0013] The above one or more technical solutions in the embodiments of the present invention have at least one or more of the following technical effects:

[0014] A Chinese medicine composition for treating leukorrhea and a preparation method thereof provided in an embodiment of the present invention comprises the following raw materials by weight: 20-35g of stir-fried Atractylodes macrocephala, 20-35g of stir-fried Chinese yam, 3-9g of ginseng, 10-20g of stir-fried white peony root, 6-15g of salt plantain seed, 6-12g of stir-fried Atractylodes lancea, 10-20g of tangerine peel, 10-20g of schizonepeta charcoal, 10-20g of bupleurum, 10-20g of cuttlebone, 10-30g of agrimony, 5-15g of Sophora flavescens, 5-15g of Cnidium monnieri, 5-15g of Kochia scoparia, 0.6-1.5g of alum, 15-25g of Smilax glabra, and 2-10g of licorice. Step 1: weighing the raw materials for preparing the Chinese medicine composition according to a preset formula, wherein the raw materials include fried Atractylodes macrocephala, fried Chinese yam, ginseng, fried white peony root, salt plantain seed, fried Atractylodes lancea, dried tangerine peel, schizonepeta carbonized, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and liquorice; Step 2: mixing the raw materials in step 1 evenly to obtain a first mixed drug and a first total drug amount; Step 3: adding cold water to the first mixed drug according to the first times of the first total drug amount, and soaking it for a first preset time; Step 4: heating and boiling the first mixed drug soaked in step 3, decocting it for a second preset time and filtering it to obtain a first medicinal residue and a first decoction; Step 5: adding a second times of water to the first medicinal residue, continuing to decoct it for a third preset time, and filtering it to obtain a second decoction; Step 6: mixing the first decoction and the second decoction, and concentrating them to a first concentrated amount to obtain a Chinese medicine decoction. By scientifically combining 17 kinds of Chinese medicinal components, utilizing the theory of traditional Chinese medicine, and treating based on syndrome differentiation, the treatment of leucorrhea focuses on removing dampness, while also strengthening the spleen and kidneys, nourishing the blood and softening the liver, and detoxifying and relieving itching. This solves the technical problems of easy recurrence, drug side effects, and drug resistance in the existing Chinese and Western medicine treatments of leucorrhea, and achieves the technical effect of a classic Chinese medicine composition, good therapeutic effect, and rapid onset of action, and a simple preparation method, low price, economy and practicality, no toxic side effects, and good drug compliance, thereby improving the cure rate of leucorrhea and reducing the recurrence rate.

[0015] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention, it can be implemented according to the contents of the specification. In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 The figure is a schematic flow chart of a method for preparing a Chinese medicine composition for treating leucorrhea according to an embodiment of the present invention;

[0017] Figure 2This is a schematic diagram of the effectiveness comparison of the clinical practice research results in the embodiments of the present invention;

[0018] Figure 3 A schematic diagram showing a comparison of cure rates of clinical practice research results in an embodiment of the present invention;

[0019] Figure 4 This is a schematic diagram of the inefficiency comparison of the clinical practice research results in the embodiments of the present invention;

[0020] Figure 5 Schematic diagram of the comparison of the incidence of adverse reactions in the clinical practice research results in the embodiments of the present invention. DETAILED DESCRIPTION

[0021] The embodiment of the present invention provides a Chinese medicine composition for treating leucorrhea and a preparation method thereof, so as to solve the technical problems of easy recurrence, drug side effects and drug resistance in the prior art of treating leucorrhea with traditional Chinese and Western medicine.

[0022] The technical solution in the embodiment of the present invention has the following general idea:

[0023] The embodiment of the present invention provides a Chinese medicine composition for treating leukorrhea and a preparation method thereof. The Chinese medicine composition comprises the following raw materials by weight: 20-35g of fried atractylodes macrocephala, 20-35g of fried yam, 3-9g of ginseng, 10-20g of fried white peony root, 6-15g of salt plantain seed, 6-12g of fried atractylodes lancea, 10-20g of tangerine peel, 10-20g of schizonepeta charcoal, 10-20g of bupleurum, 10-30g of cuttlebone, and 10-20g of schizonepeta charcoal. The raw materials for preparing the Chinese medicine composition are weighed according to a preset formula, wherein the raw materials include bran-fried Atractylodes macrocephala, bran-fried yam, ginseng, stir-fried white peony root, salt plantain seed, bran-fried Atractylodes lancea, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, Kochia scoparia, alum, Smilax glabra, and liquorice; step 2: evenly mix the raw materials in the step 1 to obtain a first mixed drug and a first total drug amount; step 3: add cold water to the first mixed drug according to the first times of the first total drug amount, and soak for a first preset time; step 4: heat and boil the first mixed drug after soaking in step 3, decoct for a second preset time and filter to obtain a first medicinal residue and a first decoction; step 5: add a second times amount of water to the first medicinal residue, continue to decoct for a third preset time, filter to obtain a second decoction; step 6: mix the first decoction and the second decoction, and concentrate to the first concentrated amount to obtain a Chinese medicine decoction, thereby achieving the technical effect that the Chinese medicine composition has a classic formula, good therapeutic effect, and fast onset, and the preparation method is simple, low-cost, economical and practical, has no toxic side effects, and has good drug compliance, thereby improving the cure rate of leucorrhea and reducing the recurrence rate.

[0024] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0025] Embodiment 1

[0026] The invention provides a traditional Chinese medicine composition for treating leukorrhea. The traditional Chinese medicine composition comprises the following raw materials by weight: 20-35g of fried atractylodes macrocephala with bran, 20-35g of fried yam with bran, 3-9g of ginseng, 10-20g of fried white peony root, 6-15g of salt plantain seed, 6-12g of fried atractylodes macrocephala with bran, 10-20g of tangerine peel, 10-20g of schizonepeta charcoal, 10-20g of bupleurum, 10-20g of cuttlebone, 10-30g of agrimony, 5-15g of sophora flavescens, 5-15g of cnidium monnieri, 5-15g of kochia scoparia, 0.6-1.5g of alum, 15-25g of smilax glabra and 2-10g of liquorice.

[0027] Specifically, the protection scope of the raw materials of the Chinese medicine composition by weight is: 20-35g of stir-fried Atractylodes macrocephala, 20-35g of stir-fried yam, 3-9g of ginseng, 10-20g of stir-fried white peony root, 6-15g of salt plantain seed, 6-12g of stir-fried Atractylodes macrocephala, 10-20g of tangerine peel, 10-20g of Schizonepeta charcoal, 10-20g of bupleurum, 10-20g of cuttlebone, 10-30g of agrimony, 5-15g of Sophora flavescens, 5-15g of Cnidium monnieri, 5-15g of Kochia scoparia, 0.6-1.5g of alum, 15-25g of Smilax glabra, and 2-10g of licorice.

[0028] Further, the present embodiment takes the following Chinese medicine composition formula as the preferred formula, that is, the best formula of the Chinese medicine composition raw materials by weight is: 30g of fried Atractylodes macrocephala, 30g of fried yam, 6g of ginseng, 15g of fried white peony root, 9g of salt plantain seed, 9g of fried Atractylodes macrocephala, 15g of tangerine peel, 15g of schizonepeta charcoal, 15g of bupleurum, 30g of cuttlebone, 30g of agrimony, 10g of Sophora flavescens, 10g of Cnidium monnieri, 10g of Kochia scoparia, 1g of alum, 20g of Smilax glabra, and 3g of licorice.

[0029] Among them, the medicinal properties of each Chinese medicinal ingredient of the present invention are introduced as follows:

[0030] Fried Atractylodes macrocephala with bran: bitter, sweet, warm. Enters the spleen and stomach meridians. Can invigorate the spleen and replenish qi, dry dampness and promote diuresis, stop sweating, and stabilize the fetus. Used for spleen deficiency, poor appetite, abdominal distension and diarrhea, phlegm and fluid, dizziness and palpitations, edema, spontaneous sweating, and restless fetus.

[0031] Fried yam with bran: sweet, neutral. Enters the spleen, lung and kidney meridians. Can nourish the spleen and stomach, promote the production of body fluid and benefit the lungs, nourish the kidneys and astringe the essence. Used for spleen deficiency, poor appetite, diarrhea, loose stools, chronic diarrhea, asthma and cough due to lung deficiency, spermatorrhea due to kidney deficiency, excessive leucorrhea, frequent urination, and deficiency heat and thirst.

[0032] Ginseng: sweet, slightly bitter, slightly warm. Enters the spleen, lung, heart, and kidney meridians. It can greatly replenish vital energy, restore the pulse and consolidate the body, nourish the spleen and lungs, promote the production of body fluid and nourish blood, calm the mind and improve intelligence. It is used for physical weakness and fainting, cold limbs and weak pulse, spleen deficiency and poor appetite, lung deficiency and wheezing and coughing, thirst due to loss of body fluid, internal heat and thirst, qi and blood deficiency, long-term illness and weakness, palpitations and insomnia, impotence and cold uterus, and is decocted separately for oral administration.

[0033] Stir-fried white peony root: bitter, sour, slightly cold. Enters the liver and spleen meridians. Can nourish blood and regulate menstruation, restrain yin and stop sweating, soften the liver and stop pain, and suppress liver yang. Used for blood deficiency, chlorosis, irregular menstruation, spontaneous sweating, night sweats, hypochondriac pain, abdominal pain, cramps in the limbs, headache and dizziness.

[0034] Salt Plantago seed: sweet, cold. Enters the liver, kidney, lung, and small intestine meridians. It can clear away heat, promote diuresis, relieve stranguria, eliminate dampness and stop diarrhea, improve eyesight, and eliminate phlegm. It is used for hot stranguria, edema, diarrhea caused by summer heat, red and swollen eyes, and cough caused by phlegm and heat. It is wrapped and decocted.

[0035] Fried Atractylodes with bran: pungent, bitter, warm. Enters the spleen, stomach, and liver meridians. Can dry dampness and strengthen the spleen, dispel wind and cold, and improve eyesight. Used for obstruction of the middle jiao, abdominal distension, diarrhea, edema, beriberi, rheumatism, colds, night blindness, and blurred vision.

[0036] Tangerine peel: bitter, pungent, warm. Enters the lung and spleen meridians. Can regulate qi and strengthen the spleen, dry dampness and resolve phlegm. Used for abdominal distension, loss of appetite, vomiting and diarrhea, cough and excessive phlegm.

[0037] Schizonepeta charcoal: pungent, astringent, slightly warm. Enters the lung and liver meridians. Astringent and hemostatic. Used for blood in stool, metrorrhagia, and postpartum blood loss.

[0038] Bupleurum: pungent, bitter, slightly cold. Enters the liver, gallbladder, and lung meridians. Can dispel fever, relieve liver depression, and raise Yang Qi. Used for colds and fever, alternating cold and heat, chest and flank pain, irregular menstruation, uterine prolapse, and rectal prolapse.

[0039] Cuttlebone: salty, astringent, warm. Enters the spleen and kidney meridians. It can astringe and stop bleeding, astringe semen and stop leukorrhea, reduce acid and relieve pain, and astringe dampness and heal sores. It is used for vomiting blood, epistaxis, metrorrhagia, bloody stool, spermatorrhea, leukorrhea, stomachache and acid regurgitation; external treatment for injury bleeding, eczema, wet sores, and ulcers that do not heal. Apply an appropriate amount externally, grind into powder and apply to the affected area.

[0040] Agrimony: bitter, astringent, neutral. Enters the heart and liver meridians. Astringent, hemostatic, antimalarial, antidysentery, detoxifying, and tonifying. Used for hemoptysis, hematemesis, metrorrhagia, malaria, bloody dysentery, carbuncle, ulcer, vaginal itching, leucorrhea, exhaustion and strain.

[0041] Sophora flavescens: bitter, cold. Entries to the heart, liver, stomach, large intestine, and bladder meridians. Clears away heat and dampness, kills parasites, and is a diuretic. Used for heat dysentery, blood in stool, jaundice, urine retention, vaginal discharge, vaginal swelling and itching, eczema, wet sores, skin itching, scabies and leprosy; external treatment of trichomonas vaginitis. Apply externally in appropriate amount, decoct in water and wash the affected area.

[0042] Cnidium monnieri: pungent, bitter, warm; slightly toxic. Enters the kidney meridian. Can dry dampness and dispel wind, kill insects and relieve itching, warm the kidney and strengthen yang. Used for vaginal itching and leucorrhea, eczema itching, dampness and low back pain, kidney deficiency and impotence, uterine cold and infertility. Appropriate amount for external use, decoct in water for fumigation and washing, or grind into powder for application.

[0043] Kochia scoparia: pungent, bitter, cold. Enters the kidney and bladder meridians. Can clear away heat and dampness, dispel wind and relieve itching. Used for painful urination, vaginal itching, leucorrhea, rashes, eczema, and skin itching. Appropriate amount for external use, decoction for fumigation and washing.

[0044] Alum: sour, astringent, cold. Enters the lung, spleen, liver, and large intestine meridians. It can be used externally to detoxify and kill insects, dry dampness and relieve itching; taken internally to stop bleeding and diarrhea, and eliminate wind and phlegm. It is used for external treatment of eczema, scabies, prolapse of the anus, hemorrhoids, and pus in the ear; taken internally for chronic diarrhea, blood in the stool, metrorrhagia, epilepsy and madness. Alum absorbs moisture and sores, stops bleeding and removes rot. It is used for eczema, wet sores, prolapse of the anus, hemorrhoids, pus in the ear, vaginal itching and leucorrhea, epistaxis, bleeding from the teeth, and nasal constriction. Apply an appropriate amount externally, grind into powder and apply or dissolve in water to wash the affected area.

[0045] Smilax glabra: sweet, light, neutral. Enters the liver and stomach meridians. Detoxifies, removes dampness, and clears the joints. Used for limb cramps and muscle and bone pain caused by syphilis and mercury poisoning; damp-heat stranguria, leucorrhea, carbuncle, scrofula, and scabies.

[0046] Licorice: sweet, neutral. Enters the heart, lung, spleen, and stomach meridians. Can nourish the spleen and replenish qi, clear away heat and detoxify, remove phlegm and relieve cough, relieve pain, and harmonize various medicines. Used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough with sputum, abdominal and limb cramps and pain, carbuncle, sore and ulcer, and relieve drug toxicity and potency.

[0047] The above information on Chinese medicinal materials is from the 2020 edition of the "Pharmacopoeia of the People's Republic of China".

[0048] Therefore, the present invention reuses Atractylodes macrocephala, Chinese yam and ginseng, which greatly replenishes the spleen and stomach qi; Atractylodes macrocephala is bitter and warm, and it can dry dampness and soothe the stomach; Bupleurum and Nepeta spicate charcoal can soothe the liver and reach depression, and can relieve the qi of the clear and vigorous; White peony root is sour and astringent, and it can nourish blood and soften the liver; Salt Plantago seed and Smilax glabra can infiltrate water and remove dampness, and can eliminate water vapor; Sophora flavescens, Cnidium monnieri, Kochia scoparia, and alum can clear away heat and dampness, kill insects and stop itching, and warm the kidney and replenish yang; Cuttlebone can collect dampness and astringe sores, and can stop leukorrhea; Agrimoniae can astringe and stop bleeding, and can stop itching by detoxification; Licorice can invigorate qi and harmonize the middle, and it can harmonize various medicines as the guiding medicine. This side can invigorate the spleen and soothe the stomach, soothe the liver and remove dampness, stop leukorrhea, and remove dampness and stop itching. This side is a classic prescription for leucorrhea with spleen deficiency and liver depression, and dampness evil bets. The problems existing in the existing western medicine treatment technology are further solved, and the technical effect of the Chinese medicine composition for the treatment of leukorrhea with remarkable efficacy, fast onset, low cost, no toxic side effects, and good drug compliance is achieved.

[0049] Embodiment 2

[0050] Figure 1 Flow chart of a method for preparing a Chinese medicine composition for treating leukorrhea in an embodiment of the present invention, which is used to prepare the Chinese medicine composition for treating leukorrhea in the aforementioned embodiment 1, such as Figure 1 As shown, the method includes:

[0051] Step 1: Weigh the raw materials for preparing the traditional Chinese medicine composition according to a preset formula, wherein the raw materials include fried Atractylodes macrocephala with bran, fried yam with bran, ginseng, fried white peony root, salt plantain seed, fried Atractylodes lancea with bran, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and licorice.

[0052] Furthermore, in step 1, the salt plantain seeds are individually packed in gauze bags.

[0053] Specifically, when preparing the Chinese medicine composition for treating leukorrhea, the raw materials need to be weighed according to the preset formula, and the preset formula is as described in the above-mentioned embodiment 1, which will not be repeated here. The raw materials include bran-fried atractylodes, bran-fried yam, ginseng, fried white peony root, salt plantain seed, bran-fried atractylodes, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and licorice, wherein the salt plantain seed needs to be individually wrapped in a gauze bag before mixing.

[0054] Step 2: Evenly mix the raw materials in step 1 to obtain a first mixed drug and a first total drug amount.

[0055] Specifically, after obtaining the above 17 kinds of traditional Chinese medicines, the next step is to evenly mix the 17 traditional Chinese medicine components to obtain their mixture and total dosage, that is, the first mixed medicine and the first total dosage.

[0056] Step 3: Add cold water to the first mixed medicine according to the first times of the first total medicine amount, and soak for a first preset time.

[0057] Furthermore, in step 3, the first preset time is 2 hours.

[0058] Specifically, after the above 17 kinds of Chinese medicine compositions are mixed, cold water is then added to the first mixed medicine according to the first times of the first total amount of medicine, and soaked for the first preset time. Among them, in this embodiment, the first times of the amount are 4 to 5 times or 8 to 10 times, and the first preset time is 2 hours (hours) as a preferred. In other words, after the above 17 kinds of Chinese medicine compositions are mixed, cold water equivalent to 4 to 5 times or 8 to 10 times the total amount of medicine is added thereto and soaked for 2 hours.

[0059] Step 4: After heating and boiling the first mixed medicine soaked in step 3, decocting for a second preset time and filtering to obtain a first medicinal residue and a first decoction.

[0060] Furthermore, the second preset time is 30 minutes.

[0061] Specifically, after the first mixed medicine is soaked for 2 hours, the first mixed medicine needs to be heated and boiled, and further decocted for a second preset time after boiling and filtered to obtain the first medicinal residue and the first decoction. In this embodiment, the second preset time is preferably 30 minutes, and the specific time can also be set according to actual needs, and is not specifically limited in this embodiment.

[0062] Step 5: adding a second amount of water to the first medicinal residue, and continuing to boil for a third preset time, filtering to obtain a second decoction;

[0063] Further, the second amount is 2 to 3 times, or the second amount is 4 to 5 times.

[0064] Furthermore, the third preset time is 20 minutes.

[0065] Specifically, after obtaining the medicinal residue, it is necessary to continue to add a second amount of water to the first medicinal residue and continue to decoct for a third preset time. In this embodiment, the amount of water added, i.e., the second amount, is preferably 2 to 3 times or 4 to 5 times the amount of the medicinal residue, wherein when the first amount in step 3 is 4 to 5 times, the second amount is selected to be 2 to 3 times, and when the first amount is 8 to 10 times, the second amount is selected to be 4 to 5 times. And further, the third preset time is 20 minutes as a preferred method. Further, after decoction, filtration is performed again to obtain a second decoction.

[0066] Step 6: Mix the first decoction and the second decoction, and concentrate them to a first concentrated amount to obtain a Chinese medicine decoction.

[0067] Specifically, the two decoctions are combined, that is, the first decoction and the second decoction are mixed, and concentrated to a first concentrated amount, and finally a Chinese medicine composition extract for treating leucorrhea can be obtained, which is the Chinese medicine decoction.

[0068] Furthermore, in this embodiment, 17 kinds of Chinese medicine compositions are mixed, 4 to 5 times the total amount of cold water is added, and soaked for 2 hours, heated to boil and then decocted for 30 minutes, and filtered; the residues are added with 2 to 3 times the amount of water and continued to be decocted for 20 minutes, filtered, and the two decoctions are combined and concentrated to 400 mL to prepare a Chinese medicine decoction, which is taken warm twice a day after meals in the morning and evening.

[0069] The present embodiment also provides a method for preparing a Chinese medicine composition for treating leukorrhea, specifically: mix 17 kinds of Chinese medicine compositions, add cold water equivalent to 8 to 10 times the total amount of the medicine, soak for 2 hours, heat to boil and then boil for 30 minutes, filter; add 4 to 5 times the amount of water to the residue and continue to boil for 20 minutes, filter, combine the two decoctions, concentrate to 800 mL, make a Chinese medicine decoction, sit in a bath for 30 minutes, once a day before going to bed.

[0070] Therefore, the present invention aims to overcome the shortcomings of the existing traditional Western medicine treatment of leukorrhea, such as easy recurrence and drug side effects, and to combine the theory of traditional Chinese medicine to study the pathogenic causes and pathogenesis of leukorrhea. Based on the theory of traditional Chinese medicine dialectics, the present invention proposes a treatment method of strengthening the spleen and soothing the liver, removing dampness and stopping leukorrhea, and detoxifying and relieving itching, and combines oral administration with external use to achieve both symptomatic and root cause treatment. Further, through scientific and reasonable prescription matching, a Chinese medicine composition for the treatment of leukorrhea with significant efficacy, fast onset, low cost, no toxic side effects, and good drug compliance is developed.

[0071] Furthermore, by scientifically combining 17 kinds of Chinese medicine components, using the theory of traditional Chinese medicine, and treating based on syndrome differentiation, the treatment of leucorrhea is mainly to remove dampness, and also to strengthen the spleen and kidney, nourish blood and soften the liver, and detoxify and relieve itching. It has achieved the technical effect of being widely used in leucorrhea caused by liver depression and spleen deficiency, dampness, and dampness and cold yin itching, and has the effects of strengthening the spleen, soothing the liver, removing dampness, and relieving itching; it can significantly improve the white color of leucorrhea, like saliva and mucus, continuous and foul smell; and it can improve the accompanying symptoms of lower abdominal pain, chest and rib fullness, dull complexion, poor diet, fatigue, sore waist and knees, etc.

[0072] Furthermore, a Chinese medicine composition is used to treat leukorrhea, treating both the symptoms and the root cause, and taking it orally and applying it externally at the same time, with a two-pronged approach. Its synergistic treatment effect is significantly better than the original Chinese medicine prescription, improving the cure rate of leukorrhea and reducing the recurrence rate. The composition has a classic formula, good therapeutic effect, fast onset, and can achieve good results in 5 to 10 days. The effective rate of treatment is 99.07%, and the cure rate is about 94.15%. In addition, the preparation method is simple, low-cost, economical and practical; and no toxic side effects have occurred, and no recurrence of the disease has been observed.

[0073] Furthermore, this embodiment provides examples for some typical cases, which are as follows:

[0074] Case 1: Ms. Zhang, female, 27 years old, married.

[0075] Initial diagnosis: The patient complained of excessive leucorrhea, which was white and curd-like, continuous, foul-smelling, and vulvar itching. It increased every month before and after menstruation, with lower abdominal pain, chest and flank distension, dull complexion, poor diet, fatigue, red tongue, white fur, and thin pulse.

[0076] Medical consultation: The patient likes cold drinks, has an irregular diet and rest schedule, works overtime in the IT industry and often stays up late. He often feels that life is fast-paced, physically overdrawn, and mentally tense. The relationship between husband and wife is not harmonious and they often quarrel due to disagreements.

[0077] Chinese medicine diagnosis: The patient's main complaint is leucorrhea, which is continuous, sticky and has a foul odor. She is diagnosed with leucorrhea (excessive leucorrhea, leucorrhea).

[0078] Analysis: Comprehensive judgment is that the liver is depressed and the spleen is weak, the kidney qi is insufficient, and dampness and turbidity are flowing downward. It is necessary to soothe the liver, strengthen the spleen and tonify the kidney, and eliminate dampness and stop leukorrhea.

[0079] After taking the present invention orally and externally, the patient was re-examined one week later. The patient complained that the amount of vaginal discharge decreased, the color was white, the quality was thin, and the symptoms were significantly alleviated, but there was still a slight foul odor, accompanied by vulvar itching; the tongue quality was normal and the pulse was thin. After taking the present invention again, the patient was re-examined one week later. The patient complained that the vaginal discharge was normal, the color was normal, the quality was thin, there was no foul odor, and there was no vulvar itching; the symptoms were completely relieved, the diet increased, and the spirit was significantly improved.

[0080] Case 2: Ms. Ge, female, 49 years old, married.

[0081] Initial diagnosis: Leucorrhea for most months, worsening for 1 week, white, continuous, thin, foul smell, increased before and after menstruation, a feeling of falling in the lower abdomen, fatigue, poor appetite, normal bowel movements and sleep at night.

[0082] Interview: The patient said that he usually eats cold food, often feels uncomfortable, sighs a lot, and has occasional pain in the ribs. His face is pale, his tongue is pale, his fur is thin and white, and his pulse is stringy and slippery.

[0083] Chinese medicine diagnosis: The patient likes to eat cold and raw food, which damages the spleen. The spleen is weak and cannot transport and transform water and dampness, which leads to dampness and turbidity, so the lower abdomen falls, the amount of vaginal discharge is large, the dampness blocks the qi mechanism, so the spirit is tired and weak, and the dampness blocks the spleen and stomach, so the appetite is poor. The emotions are not comfortable, and the liver fails to release, so the two sides are swollen and painful.

[0084] Analysis: Comprehensive judgment is liver depression and spleen deficiency, insufficient kidney qi, and dampness and turbidity. It is necessary to soothe the spleen and eliminate dampness, soothe the liver and regulate qi.

[0085] Using the oral administration combined with external sitz bath of the present invention, the symptoms were significantly alleviated after two weeks, and the symptoms disappeared after one month, and the leucorrhea returned to normal.

[0086] The efficacy evaluation criteria are:

[0087] Cured: completely cured after using the present invention, the symptoms are completely relieved; effective: the symptoms are significantly relieved after using the present invention; ineffective: the symptoms are not significantly relieved after using the present invention compared with before use.

[0088] Evaluation of treatment effect:

[0089] Through clinical research on patients with leucorrhea, the present invention has been used to treat 2050 cases of leucorrhea from 2012 to 2024, with the youngest being 18 years old and the oldest being 83 years old. Among them, 1930 cases were cured, 101 cases were effective, and 19 cases were ineffective. The total effective rate of the present invention reached 99.07%, the cure rate reached 94.15%, and the ineffective rate was 0.93%.

[0090] A random sample of 1,000 cases of leucorrhea treated with the present invention and 1,000 cases of a control group (diagnosed leucorrhea treated with Western antibiotics) were compared and analyzed for effectiveness, cure rate, inefficiency, and incidence of adverse drug reactions. The results of clinical practice studies show that the effectiveness of the present invention in treating leucorrhea is higher than that of Western antibiotic treatments, and the incidence of adverse reactions is lower than that of Western medicine treatments, which proves that the present invention is safe, economical, effective, has no side effects, and has broad clinical promotion value. Specific data statistics and analysis are shown in the following table and Figure 2 , Figure 3 , Figure 4 , Figure 5 As shown:

[0091]

[0092] Embodiment 3

[0093] The present invention also provides a method for preparing a Chinese medicine composition for treating leukorrhea, which specifically comprises:

[0094] The raw materials include: 30g of stir-fried Atractylodes macrocephala with bran, 30g of stir-fried yam with bran, 6g of ginseng, 15g of stir-fried white peony root, 9g of salt plantain seed, 9g of stir-fried Atractylodes macrocephala with bran, 15g of tangerine peel, 15g of schizonepeta charcoal, 15g of bupleurum, 30g of cuttlebone, 30g of agrimony, 10g of Sophora flavescens, 10g of Cnidium monnieri, 10g of Kochia scoparia, 1g of alum, 20g of Smilax glabra, and 3g of licorice.

[0095] Step 10: Wrap the salt plantain seeds individually in a gauze bag;

[0096] Step 20: Evenly mix 16 kinds of Chinese medicinal slices including fried Atractylodes macrocephala, fried yam, ginseng, fried white peony root, fried Atractylodes lancea, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and licorice, put them in a casserole, add water equivalent to 4 to 5 times the total amount of the medicine, put in salt plantain, and soak for 2 hours.

[0097] Step 30: First, heat with high heat to boil, then change to low heat, decoct for 30 minutes, filter; add 2-3 times the amount of water to the residue and continue to decoct for 20 minutes, filter, combine the two decoctions, concentrate to 400mL, and prepare a Chinese medicine decoction, one portion per day, warm and take twice a day after meals. Seven days is a course of treatment. Generally, patients can recover after two courses of treatment, and those with more severe symptoms need 3-4 courses of treatment.

[0098] Embodiment 4

[0099] The present invention also provides a method for preparing a Chinese medicine composition for treating leukorrhea, which specifically comprises:

[0100] The raw materials include: 30g of stir-fried Atractylodes macrocephala with bran, 30g of stir-fried yam with bran, 6g of ginseng, 15g of stir-fried white peony root, 9g of salt plantain seed, 9g of stir-fried Atractylodes macrocephala with bran, 15g of tangerine peel, 15g of schizonepeta charcoal, 15g of bupleurum, 30g of cuttlebone, 30g of agrimony, 10g of Sophora flavescens, 10g of Cnidium monnieri, 10g of Kochia scoparia, 1g of alum, 20g of Smilax glabra, and 3g of licorice.

[0101] Step 100: Wrap the salt plantain seeds individually in a gauze bag;

[0102] Step 200: Evenly mix 16 kinds of Chinese medicinal slices including fried Atractylodes macrocephala, fried Chinese yam, ginseng, fried white peony root, fried Atractylodes lancea, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and licorice, put them in a casserole, add water equivalent to 8 to 10 times the total amount of the medicine, put in salt plantain seed, and soak for 2 hours.

[0103] Step 300: first heat with high heat to boil, then change to low heat, boil for 30 minutes, filter; add 4 to 5 times the amount of water to the residue and continue boiling for 20 minutes, filter, combine the two decoctions, concentrate to 800 mL, prepare a Chinese medicine decoction, sit in the bath for 30 minutes, once a day before going to bed.

[0104] The above one or more technical solutions in the embodiments of the present invention have at least one or more of the following technical effects:

[0105] A Chinese medicine composition for treating leukorrhea and a preparation method thereof provided in an embodiment of the present invention comprises the following raw materials by weight: 20-35g of stir-fried Atractylodes macrocephala, 20-35g of stir-fried Chinese yam, 3-9g of ginseng, 10-20g of stir-fried white peony root, 6-15g of salt plantain seed, 6-12g of stir-fried Atractylodes lancea, 10-20g of tangerine peel, 10-20g of schizonepeta charcoal, 10-20g of bupleurum, 10-20g of cuttlebone, 10-30g of agrimony, 5-15g of Sophora flavescens, 5-15g of Cnidium monnieri, 5-15g of Kochia scoparia, 0.6-1.5g of alum, 15-25g of Smilax glabra, and 2-10g of licorice. Step 1: weighing the raw materials for preparing the Chinese medicine composition according to a preset formula, wherein the raw materials include bran-fried Atractylodes macrocephala, bran-fried Chinese yam, ginseng, stir-fried white peony root, salt plantain seed, bran-fried Atractylodes lancea, tangerine peel, schizonepeta carbonized, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and liquorice; Step 2: mixing the raw materials in step 1 evenly to obtain a first mixed drug and a first total drug amount; Step 3: adding cold water to the first mixed drug according to a first multiple of the first total drug amount, and soaking it for a first preset time; Step 4: heating and boiling the first mixed drug soaked in step 3, decocting it for a second preset time and filtering it to obtain a first drug residue and a first decoction; Step 5: adding cold water to the first mixed drug Add a second amount of water to the medicinal residue, and continue to boil for a third preset time, then filter to obtain a second decoction; step 6: mix the first decoction and the second decoction, and concentrate them to the first concentrated amount to obtain a Chinese medicine decoction, by scientifically combining 17 kinds of Chinese medicinal components, using the theory of traditional Chinese medicine, syndrome differentiation and treatment, the treatment of leucorrhea is mainly to eliminate dampness, and also to strengthen the spleen and kidney, nourish blood and soften the liver, detoxify and relieve itching, thereby solving the technical problems of easy recurrence, drug side effects and drug resistance in the prior art of Chinese and Western medicine treatment of leucorrhea, achieving the Chinese medicine composition with classic formula, good therapeutic effect and fast onset, simple preparation method, low price, economy and practicality, no toxic side effects, good drug compliance, improving the cure rate of leucorrhea and reducing the recurrence rate.

[0106] Although the preferred embodiments of the present invention have been described, those skilled in the art may make additional changes and modifications to these embodiments once they have learned the basic creative concept. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the present invention.

[0107] Obviously, those skilled in the art can make various changes and modifications to the embodiments of the present invention without departing from the spirit and scope of the embodiments of the present invention. Thus, if these modifications and variations of the embodiments of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A Chinese medicine composition for treating leucorrhea, characterized in that: The Chinese medicine composition includes the following raw materials by weight: The ingredients of the medicine are 20-35g of stir-fried Atractylodes macrocephala with bran, 20-35g of stir-fried yam with bran, 3-9g of ginseng, 10-20g of stir-fried white peony root, 6-15g of plantain seed with salt, 6-12g of stir-fried Atractylodes lancea with bran, 10-20g of dried tangerine peel, 10-20g of schizonepeta charcoal, 10-20g of bupleurum, 10-20g of cuttlebone, 10-30g of agrimony, 10-30g of sophora flavescens, 5-15g of cnidium monnieri, 5-15g of kochia scoparia, 0.6-1.5g of alum, 15-25g of wild yam, and 2-10g of licorice.

2. A method for preparing a Chinese medicine composition for treating leukorrhea, which is used to prepare the aforementioned Chinese medicine composition for treating leukorrhea, characterized in that: The method comprises: Step 1: weighing the raw materials for preparing the traditional Chinese medicine composition according to a preset formula, wherein the raw materials include fried atractylodes macrocephala with bran, fried yam with bran, ginseng, fried white peony root, salt plantain seed, fried atractylodes lancea with bran, tangerine peel, schizonepeta charcoal, bupleurum, cuttlebone, agrimony, sophora flavescens, cnidium monnieri, kochia scoparia, alum, smilax glabra, and licorice; Step 2: Evenly mix the raw materials in step 1 to obtain a first mixed drug and a first total drug amount; Step 3: adding cold water to the first mixed medicine according to a first multiple of the first total medicine amount, and soaking for a first preset time; Step 4: After heating and boiling the first mixed medicine soaked in step 3, decocting for a second preset time and filtering to obtain a first medicinal residue and a first decoction; Step 5: adding a second amount of water to the first medicinal residue, and continuing to boil for a third preset time, filtering to obtain a second decoction; Step 6: Mix the first decoction and the second decoction, and concentrate them to a first concentrated amount to obtain a Chinese medicine decoction.

3. The method for preparing the Chinese medicine composition for treating leukorrhea as claimed in claim 2, characterized in that: In the step 1, the salt plantain seeds are individually packed in a gauze bag.

4. The method for preparing the Chinese medicine composition for treating leukorrhea as claimed in claim 2, characterized in that: In step 3, the first preset time is 2 hours.

5. The method for preparing the Chinese medicine composition for treating leukorrhea as claimed in claim 2, characterized in that: The first amount is 4 to 5 times, and the second amount is 2 to 3 times, or the first amount is 8 to 10 times, and the second amount is 4 to 5 times.

6. The method for preparing the Chinese medicine composition for treating leukorrhea according to claim 2, characterized in that: In step 4, the second preset time is 30 minutes.

7. The method for preparing the Chinese medicine composition for treating leukorrhea according to claim 2, characterized in that: In step 5, the third preset time is 20 minutes.

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