Emergency suspended red blood cell rapid heating device
By designing a heating device that is directly in contact with suspended red blood cells and using the cold amount generated by the heating equipment for refrigeration, the problems of uneven heating and energy loss of suspended red blood cells are solved, and rapid, uniform heating and efficient energy utilization are achieved.
Patent Information
- Application Number
- CN202411751313.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-02
- Publication Date
- 2025-03-04
AI Technical Summary
In the prior art, the heating of suspended red blood cells is uneven, resulting in a slow heating rate and the inability to effectively refrigerate using the cold amount generated by the heating equipment.
A rapid heating device for suspended red blood cells for first aid is designed, and the heat exchanger is directly contacted with the flowing suspended red blood cells through the heating tube and the heat conducting rod, and the uninjected suspended red blood cells are refrigerated using the cold amount generated by the heating mechanism.
The rapid and uniform heating of suspended red blood cells is achieved, the heating rate is improved, and the energy consumption is reduced by effectively utilizing the cold volume and the energy utilization rate is improved.
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Figure CN119548714A_ABST
Abstract
Description
Technical Field
[0001] The invention patent relates to the field of medical device technology, specifically, to a device for rapidly heating suspended red blood cells for emergency use. Background Art
[0002] Suspended red blood cells refer to the red blood cell component with an appropriate amount of additives added to concentrated red blood cells. Specifically, it is a red blood cell component blood made by separating most of the plasma from the whole blood collected in a multi-bag under fully closed conditions, and adding red blood cell additives to the remaining part. Suspended red blood cells are the most widely used red blood cell preparation in clinical practice at home and abroad, and are suitable for most patients who need to supplement red blood cells and improve the oxygen-carrying capacity of their blood. Suspended red blood cells are generally prepared using the multi-bag method. The main function of this red blood cell preparation is to enhance the oxygen-carrying capacity of red blood cells, and is suitable for most patients who need to supplement red blood cells and improve the oxygen-carrying capacity of their blood.
[0003] The refrigeration temperature of suspended red blood cells is 2-6°C. When it is necessary to inject suspended red blood cells into the patient, a specified amount of suspended red blood cells must be taken out and heated to about 37°C, and then the heated suspended red blood cells must be injected into the patient. For the heating of suspended red blood cells, a water bath heating method is generally used. For example, a rapid warmer for suspended red blood cells used for emergency treatment is disclosed in a Chinese utility patent (CN214633199U). The warmer is to pass warm water into a water bath, and the suspended red blood cells are placed inside a double-layer tray. The warm water heats the suspended red blood cells through heat conduction until the temperature of the suspended red blood cells is heated to about 37°C. In order to increase the heating rate, a stirring blade is also provided in the water bath of the warmer. The stirring blade rotates to fully exchange heat between the warm water and the tray, thereby increasing the heating rate. However, in this way, due to the limitation of the size of the contact surface between the tray and the warm water, the suspended red blood cells are heated unevenly, and the heating rate of the suspended red blood cells away from the contact surface is slower.
[0004] In order to increase the heating rate, the main method is to increase the heating surface area. Therefore, heating the flowing suspended red blood cells can increase the temperature most quickly. For example, a Chinese invention patent (CN1620319A) discloses a rapid heating device for suspended red blood cells for emergency treatment. The heating device passes the blood into a transparent spiral catheter and then heats it through infrared lamp radiation, so that the blood flowing out of the spiral catheter reaches a specified temperature. Although the heating rate of the blood can be increased by using radiation heat transfer on the basis of increasing the heating area, radiation heat exchange can only make the side of the spiral catheter facing the infrared lamp become the heating surface, and the back side cannot be effectively heated. Therefore, in response to the above technical problems, the applicant invented a heating device that uses a heating device to directly contact the suspended red blood cells. Summary of the invention
[0005] The purpose of the present invention is to provide a device for rapidly heating suspended red blood cells for emergency use. The device can increase the temperature of suspended red blood cells at the fastest speed by directly contacting and exchanging heat with flowing suspended red blood cells through heating tubes and heat-conducting rods. At the same time, the device also makes full use of the cold energy generated by the heating device to refrigerate the uninjected suspended red blood cells, thereby reducing energy loss.
[0006] The present invention is implemented as follows: a device for rapidly heating suspended red blood cells for emergency use comprises a box body, a storage box and a refrigerator box are installed in the box body, a storage box for storing suspended red blood cells is fixedly installed in the refrigerator box, the top opening of the storage box is located at the top of the box body, the refrigerator box is filled with liquid for cooling the storage box, a delivery pipe with an electromagnetic valve is arranged between the storage box and the storage box; two peristaltic pumps are arranged in parallel in the box body, a driving mechanism is arranged between the two peristaltic pumps, and the driving mechanism can simultaneously drive the two peristaltic pumps to rotate in the same direction, wherein The liquid inlet and liquid outlet of a peristaltic pump are both connected to connecting pipes, the other end of the connecting pipe connected to the liquid inlet of the peristaltic pump is connected to the storage box, and the other end of the connecting pipe connected to the liquid outlet of the peristaltic pump is used to output suspended red blood cells to the outside of the box; heating mechanisms are installed on the two connecting pipes, the heating end of the heating mechanism is located on the connecting pipe to directly heat the suspended red blood cells flowing through, and the cooling end of the heating mechanism is used to cool the liquid in the refrigerator; the liquid inlet and liquid outlet of another peristaltic pump are both connected to the heating mechanism, and the peristaltic pump is used for the water circulation system of the heating mechanism.
[0007] Furthermore, the heating mechanism includes a liquid outlet pipe 1, a liquid return pipe 1, two connecting blocks and two heating units; the ends of the liquid outlet pipe 1 and the liquid return pipe 1 are fixedly connected to the side wall of the refrigerator; the ends of the liquid outlet pipe 1 and the liquid return pipe 1 away from the refrigerator are respectively connected to the liquid inlet end and the liquid outlet end of the peristaltic pump; one of the connecting blocks is simultaneously sleeved on the connecting pipe and the liquid outlet pipe 1, and the other connecting block is simultaneously sleeved on the connecting pipe and the liquid return pipe 1; the two heating units are both installed in the two connecting blocks, the heating ends of the two heating units are both located in the connecting pipe, the cooling end of one heating unit is located in the liquid outlet pipe 1, and the cooling end of the other heating unit is located in the liquid return pipe 1.
[0008] Furthermore, the heating unit includes two heat conducting plates, a plurality of refrigeration semiconductors and a plurality of heat exchange rods, the plurality of refrigeration semiconductors are arranged along the length direction of the connecting tube, and the two ends of the refrigeration semiconductors are respectively fixedly connected to the two heat conducting plates, one of the heat conducting plates is embedded in the side wall of the connecting tube, and the other heat conducting plate is embedded in the side wall of the liquid outlet pipe 1 or the liquid return pipe 1.
[0009] Furthermore, the heating mechanism includes two heat exchange sleeves, a connecting pipe and a compressor refrigeration system; the two heat exchange sleeves are fixedly sleeved on the two connecting pipes respectively, the two ends of the connecting pipe are fixedly connected to the ends of the two heat exchange sleeves respectively, and the side walls of the two heat exchange sleeves are fixedly connected to the liquid inlet and liquid outlet of one of the peristaltic pumps respectively; the heating end of the compressor refrigeration system is located in the heat exchange sleeve, and the refrigeration end of the compressor refrigeration system is located in the refrigerator;
[0010] The compressor refrigeration system includes a spiral tube, a coil, a throttling element and a compressor; the exhaust end of the compressor is connected to the spiral tube, the air intake end of the compressor is connected to the coil, and the liquid inlet end and the liquid outlet end of the throttling element are connected to the spiral tube and the coil respectively.
[0011] Furthermore, the end of the connecting tube connected to the liquid outlet end of the peristaltic pump is also connected to a flow direction regulating valve, and the side wall of the flow direction regulating valve is also connected to a return liquid pipe 2 and a liquid outlet pipe 2, the end of the liquid outlet pipe 2 away from the flow direction regulating valve is located outside the box, the end of the return liquid pipe 2 away from the flow direction regulating valve is connected to a spiral heating tube, and the end of the spiral heating tube away from the return liquid pipe 2 is connected to the storage box; the flow direction regulating valve is used to adjust the flow direction of suspended red blood cells in the connecting tube; the box is located directly above the spiral heating tube and is detachably provided with a cover.
[0012] Furthermore, the flow direction regulating valve includes a spherical shell, a rotating sphere and a stepper motor, and the connecting pipe, the second reflux pipe and the second liquid outlet pipe are all fixedly connected to the side wall of the spherical shell; the rotating sphere is located in the spherical shell, the stepper motor is fixedly installed on the outer wall of the spherical shell, and the output end of the stepper motor is fixedly connected to the side wall of the rotating sphere; an L-shaped channel is opened in the rotating sphere, one end of the L-shaped channel is always connected to the connecting pipe, and the other end can be connected to the second reflux pipe and the second liquid outlet pipe respectively under the drive of the stepper motor.
[0013] Furthermore, the driving mechanism includes a driving motor and two transmission units; the output end of the driving motor is connected to one of the transmission units, the power output ends of the two transmission units are respectively fixedly connected to the power input ends of the peristaltic pump, and the two transmission units are meshed;
[0014] The transmission unit includes a transmission shaft, a spur gear, an output shaft and two meshing bevel gears; the two bevel gears are fixedly sleeved on the transmission shaft and the output shaft respectively, and the spur gear is also fixedly sleeved on the transmission shaft; the spur gears of the two transmission units are meshed with each other; the end of the transmission shaft of one of the transmission units is fixedly connected to the power output end of the drive motor; the end of the output shaft is fixedly connected to the rotating axis of the peristaltic pump.
[0015] Furthermore, the peristaltic pump includes a pressurizing shell, a hose, a rotating shaft and a plurality of pressurizing devices, wherein the plurality of pressurizing devices are installed on the rotating side wall of the rotating shaft with equal arc length, and the rotating shaft is sleeved on the output shaft; the interior of the pressurizing shell is a semicircular cavity with an opening on one side, the hose is attached to the inner arc wall surface of the pressurizing shell, and the two ends of the hose are respectively connected to two connecting pipes; the pressurizing device can squeeze the hose;
[0016] The pressurizing device includes an extrusion roller, a connecting rod and an adjusting unit; the two ends of the connecting rod are respectively connected to the rotating shaft and the extrusion roller, the extrusion roller can extrude the hose, and the adjusting unit is installed on the pressurizing shell to adjust the extrusion state between the extrusion roller and the hose.
[0017] Furthermore, the rotating shaft is a hollow rotating shaft, which is fixedly sleeved on the output shaft; the connecting rod is a telescopic connecting rod, and the interior of the connecting rod is connected to the interior of the rotating shaft; the adjusting unit includes a connecting cylinder, a threaded rod, a piston and a servo motor; one end of the connecting cylinder is fixedly connected to the inner wall of the pressurized shell, and the other end of the connecting cylinder is rotatably connected to the axis center of the hollow rotating shaft and is connected to the interior of the rotating shaft; the servo motor is fixedly installed on the outer wall of the pressurized shell, the output end of the servo motor is fixedly connected to the end of the threaded rod, the piston is sleeved on the threaded section of the threaded rod, and the piston is in sealing and sliding contact with the inner wall of the connecting cylinder.
[0018] Furthermore, the rotating shaft is rotatably sleeved on the output shaft, and the adjusting unit includes a transmission disc, a telescopic sleeve, a screw and a second servo motor; the transmission disc is slidably sleeved on the output shaft, and an annular groove is provided on the side wall of the transmission disc, and the transmission disc and the opposite side wall of the rotating shaft can engage; the second servo motor is fixedly installed on the inner wall of the pressurized shell, the end of the screw is fixedly connected to the output end of the second servo motor, the telescopic sleeve is sleeved on the screw, and the top protruding position of the telescopic sleeve is located in the annular groove and in contact with the transmission disc.
[0019] Compared with the prior art, the present invention has the following beneficial effects:
[0020] 1. Install the heating end of the heating mechanism on two connecting pipes, and install the cooling end of the heating mechanism in the refrigerator. Both connecting pipes are connected to the inlet and outlet liquid ends of the peristaltic pump. In this way, the heating mechanism can not only quickly heat the flowing suspended red blood cells, but also use the cold energy generated by the heating mechanism to cool the liquid in the refrigerator, so as to refrigerate the uninjected suspended red blood cells;
[0021] 2. The heating method of the heating mechanism is set to refrigeration semiconductor heating, so that the whole heating device is light in weight, which is convenient for medical staff to carry outside, and the heating device can be used in field emergency scenarios; at the same time, the liquid flowing in the liquid outlet pipe 1 and the liquid return pipe 1 is in contact with the refrigeration end of the refrigeration semiconductor for heat exchange, and the suspended red blood cells flowing in the connecting pipe are in contact with the heating end of the refrigeration semiconductor for heat exchange, so that the refrigeration semiconductor can not only achieve rapid heating of the suspended red blood cells, but also achieve refrigeration of the uninjected suspended red blood cells, thereby improving the energy utilization rate;
[0022] 3. The heating mechanism is set to a single-stage compression refrigeration cycle heating mode, which has a higher heating rate and can be used in emergency situations in hospitals; the heat exchange sleeve is directly sleeved on two connecting pipes, and a water circulation system consisting of two heat exchange sleeves, connecting pipes and peristaltic pumps is formed. The heating end of the single-stage compression refrigeration cycle is located in the heat exchange sleeve to heat the circulating water, thereby quickly heating the suspended red blood cells flowing in the connecting pipe. The cooling end of the single-stage compression refrigeration cycle is set in the refrigerator to cool the liquid in the refrigerator, thereby refrigerating the uninjected suspended red blood cells, thereby improving the energy utilization rate;
[0023] 4. A flow direction regulating valve is arranged at the end of the connecting pipe, and the flow direction regulating valve is connected to the return liquid pipe 2 and the outlet liquid pipe 2. The return liquid pipe 2 is connected to the storage box through the spiral heating pipe, so that an internal circulation heating structure is formed between the peristaltic pump, the connecting pipe, the storage box, the spiral heating pipe and the return liquid pipe 2, which can not only make the suspended red blood cells that are not fully heated in the connecting pipe in the initial state of the secondary release flow back to the storage box for reheating, but also can use the heat emitted by the suspended red blood cells flowing through the spiral heating pipe to preheat the infusion bottle / bag, so as to avoid a large temperature change of the suspended red blood cells at about 37°C after flowing out of the outlet liquid pipe 2 into the infusion bottle;
[0024] 5. The connecting rod of the peristaltic pump is set as a retractable railing, the rotating shaft is set as a hollow rotating shaft, and an adjustment unit is set on one side of the rotating shaft. The adjustment unit, the hollow rotating shaft and the telescopic connecting rod form a sealed chamber. The length of the connecting rod can be adjusted by the action of the piston in the adjustment unit, thereby adjusting the state of the squeezing roller squeezing the hose, so as to achieve separate adjustment of the pressurization state of the two peristaltic pumps. In this way, when the suspended red blood cells are not injected, a single peristaltic pump can be used to pressurize the hose so that the suspended red blood cells can be refrigerated normally; in addition, the same technical effect can be achieved by controlling whether the power of the output shaft can be transmitted to the rotating shaft by meshing the transmission disk with the rotating shaft;
[0025] 6. A driving mechanism is arranged between the two peristaltic pumps, and the driving mechanism includes a driving motor and two transmission units. The two transmission units are meshed with each other, and the power output ends of the two transmission units are respectively fixedly connected to the rotating shafts of the two peristaltic pumps. In this way, the two peristaltic pumps can be driven to rotate at the same time by the driving motor, achieving an effect of one machine with multiple uses. In addition, by setting up two transmission units, the two peristaltic pumps can rotate in the same direction. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] Figure 1 This is a schematic structural diagram of a device for rapidly heating suspended red blood cells for emergency use provided in Example 1 of the present invention;
[0027] Figure 2 is a diagram showing the connection relationship between the refrigeration semiconductor, the connecting pipe and the liquid outlet pipe 1 provided in Example 1 of the present invention;
[0028] Figure 3 is a side sectional view of the peristaltic pump provided in Example 1 of the present invention;
[0029] Figure 4 is a front cross-sectional view of two peristaltic pumps arranged side by side at the rotating shaft position in Example 1 of the present invention;
[0030] Figure 5 yes Figure 4 The enlarged view of point A in the middle;
[0031] Figure 6 is a structural schematic diagram of a flow direction regulating valve in Embodiment 1 of the present invention;
[0032] Figure 7 It is a front view of a device for rapidly heating suspended red blood cells for emergency use provided in Example 1 of the present invention;
[0033] Figure 8 This is a schematic diagram of the structure of a device for rapidly heating suspended red blood cells for emergency use provided in Example 2 of the present invention;
[0034] Fig. 9 is a top cross-sectional view of the heat exchange sleeve in Example 2 of the present invention;
[0035] Fig.10 is a front cross-sectional view of two peristaltic pumps arranged side by side at the rotating shaft position in Example 3 of the present invention;
[0036] Fig.11 yes Fig.10 Enlarged view of point A in the middle.
[0037] Reference numerals in the above drawings:
[0038] 1. Box; 2. Pressurized shell; 3. Hose; 4. Connecting block; 5. Connecting pipe; 6. Liquid outlet pipe 2; 7. Spherical shell; 8. Liquid return pipe 2; 9. Storage box; 10. Spiral heating pipe; 11. Infusion bottle; 12. Cover; 13. Partition; 14. Liquid return pipe 1; 15. Storage box; 16. Refrigeration box; 17. Liquid outlet pipe 1; 18. Delivery pipe; 19. Solenoid valve; 20. Output shaft; 21. Refrigeration semiconductor; 22. Heat conduction plate; 23. Heat exchange rod; 24. Connecting rod; 25. Extrusion roller; 26. Rotating shaft; 27. Bevel gear; 28. Transmission shaft; 29, spur gear; 30, servo motor one; 31, U-shaped frame; 32, drive motor; 33, connecting plate; 34, threaded rod; 35, piston; 36, connecting cylinder; 37, L-shaped channel; 38, stepper motor; 39, rotating ball; 40, shoulder strap; 41, control panel; 42, coil; 43, electronic expansion valve; 44, spiral tube; 45, heat exchange sleeve; 46, connecting pipe; 47, compressor; 48, telescopic sleeve; 49, annular groove; 50, transmission plate; 51, screw rod; 52, telescopic rod; 53, servo motor two. DETAILED DESCRIPTION
[0039] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.
[0040] The implementation of the present invention is described in detail below in conjunction with specific embodiments.
[0041] The same or similar numbers in the drawings of this embodiment correspond to the same or similar parts; in the description of the present invention, it should be understood that if the terms "upper", "lower", "left", "right" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, it is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and cannot be understood as limitations on this patent. For ordinary technicians in this field, the specific meanings of the above terms can be understood according to specific circumstances.
[0042] Reference Figure 1-11 The figure shows a preferred embodiment of the present invention.
[0043] Embodiment 1: A device for rapidly heating suspended red blood cells for emergency use, comprising a housing 1, in which a storage box 9 and a refrigerator 16 are fixedly installed. Figure 1As shown, a preservation box 15 for preserving suspended red blood cells is fixedly installed in the refrigerator 16. The top of the preservation box 15 is open, and the cover 12 is tightened to achieve sealed preservation of the suspended red blood cells. In this embodiment, in order to improve the refrigeration effect of the suspended red blood cells, the bottom surface of the preservation box 15 does not touch the bottom of the refrigerator 16. The heat-conducting medium loaded in the refrigerator 16 is water, so that the water transfers the cold energy to the preservation box 15 through the bottom and side of the preservation box 15, thereby achieving the effect of refrigerating the suspended red blood cells. A delivery pipe 18 is fixedly installed between the preservation box 15 and the storage box 9, and a solenoid valve 19 is installed on the delivery pipe 18. In order to reduce the use of the pump body, one end of the delivery pipe 18 is connected to the side wall of the preservation box 15 near its bottom, and the other end is connected to the side wall of the storage box 9 near its top. The delivery pipe 18 is arranged horizontally. Two peristaltic pumps are fixedly installed in parallel in the box body 1, and a driving mechanism is installed between the two peristaltic pumps. The driving mechanism can simultaneously drive the two peristaltic pumps to rotate in the same direction. The mechanism of peristaltic pump is as follows Figure 3 As shown, it is mainly composed of a pressurized shell 2, a hose 3, a rotating shaft 26 and three groups of pressurizing devices. The three groups of pressurizing devices are installed on the rotating side wall of the rotating shaft 26 with equal arc lengths, and the axis of the rotating shaft 26 is connected to the power output end of the driving mechanism; the interior of the pressurized shell 2 is a semicircular cavity with an opening on one side, the hose 3 is attached to the inner arc wall surface of the pressurized shell 2, and the two ends of the hose 3 are respectively connected to two connecting pipes 5; the pressurizing device can squeeze the hose 3 under the rotation of the rotating shaft 26, thereby realizing pressurized transportation of the fluid in the pipeline.
[0044] The two ends of the hose 3 of one of the peristaltic pumps are respectively connected with connecting pipes 5, the other end of the connecting pipe 5 connected to the liquid inlet end of the hose 3 is connected to the bottom of the storage box 9, and the connecting pipe 5 connected to the liquid outlet end of the hose 3 is installed with a flow direction regulating valve, and the flow direction regulating valve is also fixedly connected with the second liquid outlet pipe 6 and the second liquid return pipe 8, and the end of the second liquid return pipe 8 away from the spherical shell 7 is connected with a spiral heating pipe 10, and the end of the spiral heating pipe 10 away from the second liquid return pipe 8 is fixedly connected to the top of the storage box 9. A heating mechanism is installed on the two connecting pipes 5, and the heating end of the heating mechanism is located on the connecting pipe 5 to directly heat the suspended red blood cells flowing through. In this way, an internal closed-loop circulation heating system for rapidly heating the suspended red blood cells is formed between the storage box 9, the peristaltic pump, the two connecting pipes 5, the second liquid return pipe 8 and the spiral heating pipe 10. In order to prevent the temperature of the cold storage box 16 from affecting the temperature of the spiral heating pipe 10 and the storage box 9, a partition 13 is set between the cold storage box 16 and the storage box 9 in this embodiment. Through the above arrangement, when the suspended red blood cells are released into the infusion bottle 11 for the second time, since the temperature of the suspended red blood cells retained in the connecting tube 5 after the last release is relatively low, especially the suspended red blood cells between the heating mechanism and the flow direction regulating valve, if they are directly released at this time, they cannot be heated by the heating mechanism, so it is necessary to pressurize and return this part of the suspended red blood cells to the storage box 9, and then heat them through the connecting tube 5, so that the suspended red blood cells finally flowing out of the outlet tube 2 6 can be around 37°C. The spiral heating tube 10 is provided, and the infusion bottle 11 / bag can be placed in the middle or around the spiral heating tube 10, so that the heat emitted by the refluxed suspended red blood cells can preheat them, avoiding a large temperature change after the suspended red blood cells are added to the infusion bottle 11. In order to facilitate the removal of the infusion bottle 11, a detachable cover 12 is also installed on the top of the box body 1 by means of threads.
[0045] In this embodiment, Figure 1 As shown, a liquid outlet pipe 17 and a liquid return pipe 14 are installed at the top and bottom of the cold storage box 16, respectively. The other end of the liquid outlet pipe 17 is connected to the liquid inlet end of the hose 3 of another peristaltic pump, and the other end of the liquid return pipe 14 is connected to the liquid outlet end of the hose 3. In this way, a water circulation system is formed between the cold storage box 16, the liquid outlet pipe 17, the peristaltic pump and the liquid return pipe 14. At the same time, a connecting block 4 is sleeved on the connecting pipe 5 and the liquid outlet pipe 17, and a connecting block 4 is also sleeved on another connecting pipe 5 and the liquid return pipe 14. A heating unit is arranged in the connecting block 4, and the heating end of the heating unit is connected to the connecting pipe 5, and the cooling end of the heating unit is connected to the liquid outlet pipe 17 or the liquid return pipe 14. The liquid outlet pipe 17, the liquid return pipe 14, the two connecting blocks 4 and the two heating units constitute the above-mentioned heating mechanism. Figure 2As shown, the heating unit is mainly composed of two heat conducting plates 22 and multiple groups of NP refrigeration semiconductors 21. Multiple refrigeration semiconductors 21 are arranged along the length direction of the connecting tube 5. The two ends of the refrigeration semiconductors 21 are fixedly connected to the two heat conducting plates 22 respectively. One heat conducting plate 22 is embedded in the side wall of the connecting tube 5, and the other heat conducting plate 22 is embedded in the side wall of the liquid outlet pipe 17 or the liquid return pipe 14. In order to fully exchange heat with the flowing suspended red blood cells, multiple heat exchange rods 23 connected to the heat conducting plates 22 are arranged in the connecting tube 5, the liquid outlet pipe 17 and the liquid return pipe 14. The refrigeration semiconductor 21 generates heat at one end close to the connecting tube 5 and generates cold at the other end. The generated heat is used to heat the flowing suspended red blood cells, and the generated cold is used to cool the circulating water, so as to achieve the effect of refrigerating the uninjected suspended red blood cells.
[0046] In this embodiment, Figure 6 As shown, the flow direction regulating valve is mainly composed of a spherical shell 7, a rotating sphere 39 and a stepper motor 38. The connecting pipe 5, the reflux pipe 2 and the liquid outlet pipe 2 6 are all fixedly connected to the side wall of the spherical shell 7. The connecting pipe 5 and the reflux pipe 2 and the liquid outlet pipe 2 6 are arranged at an angle of 90°. The rotating sphere 39 is located in the spherical shell 7. The stepper motor 38 is fixedly installed on the outer side wall of the spherical shell 7. The output end of the stepper motor 38 is fixedly connected to the side wall of the rotating sphere 39. The stepper motor 38 can drive the rotating sphere 39 to rotate in the spherical shell 7. An L-shaped channel 37 is opened in the rotating sphere 39. One end of the L-shaped channel 37 is always connected to the connecting pipe 5, and the other end can be connected to the reflux pipe 2 and the liquid outlet pipe 2 6 respectively under the drive of the stepper motor 38. By designing the flow direction regulating valve, the outflowing suspended red blood cells can be kept at around 37°C. When it is not necessary to release the suspended red blood cells, it is only necessary to adjust the L-shaped channel 37 to be disconnected from the return pipe 2 and the liquid outlet pipe 2 6, so the flow direction regulating valve also plays the role of a conventional valve.
[0047] like Figure 4 As shown, the driving mechanism mainly consists of a driving motor 32 and two transmission units; in order to improve the stability of the driving mechanism, a connecting plate 33 is fixedly installed between the two pressurized shells 2, the driving motor 32 is installed on the connecting plate 33, the output end of the driving motor 32 is connected to one of the transmission units, the power output ends of the two transmission units are respectively fixedly connected to the power input ends of the peristaltic pump, and the two transmission units are meshed;
[0048] Combination Figure 4As shown, the transmission unit is mainly composed of a transmission shaft 28, a spur gear 29, an output shaft 20 and two meshing bevel gears 27; the two bevel gears 27 are fixedly sleeved on the transmission shaft 28 and the output shaft 20 respectively, and the spur gear 29 is also fixedly sleeved on the transmission shaft 28; the spur gears 29 of the two transmission units are meshed with each other; the end of the transmission shaft 28 of one of the transmission units is fixedly connected to the power output end of the drive motor 32, and the end of the transmission shaft 28 of the other transmission unit is connected to the bottom of the connecting plate 33 by means of a bearing; the end of the output shaft 20 is fixedly connected to the rotating axis of the peristaltic pump.
[0049] In this embodiment, the pressure device is mainly composed of a squeezing roller 25, a connecting rod 24 and an adjusting unit; Figure 3 and Figure 4 As shown, one end of the connecting rod 24 is fixedly connected to the rotating side wall of the rotating shaft 26, and the other end of the connecting rod 24 is connected to the squeezing roller 25 through the U-shaped frame 31, and the squeezing roller 25 is rotatably sleeved on the U-shaped frame 31. The connecting rod 24 of this embodiment is a telescopic connecting rod 24, and the rotating shaft 26 is a hollow rotating shaft 26. The rotating shaft 26 is fixedly sleeved on the output shaft 20 of the driving mechanism, and the rotating shaft 26 is connected to the inside of the connecting rod 24.
[0050] In order to be able to independently control the pressurization states of the two peristaltic pumps, the regulating unit of this embodiment is as follows Figure 5 As shown, it is mainly composed of a connecting cylinder 36, a threaded rod 34, a piston 35 and a servo motor 30; one end of the connecting cylinder 36 is fixedly connected to the inner wall of the pressurized shell 2, and the other end of the connecting cylinder 36 is rotatably connected to the axis of the hollow rotating shaft 26 by a rotating ring, and the connecting cylinder 36 is connected to the inside of the rotating shaft 26; the servo motor 30 is fixedly installed on the outer wall of the pressurized shell 2, the output end of the servo motor 30 is fixedly connected to the end of the threaded rod 34, the piston 35 is sleeved on the threaded section of the threaded rod 34, and the piston 35 is in sealing and sliding contact with the inner wall of the connecting cylinder 36; a sealed space is formed inside the piston 35, the connecting rod 24 and the rotating shaft 26. When the peristaltic pump is required to pressurize, the threaded rod 34 rotates forward, driving the piston 35 to move toward the rotating shaft 26. Under the action of gas pressure, the three connecting rods 24 are pushed to extend, so that the squeezing roller 25 squeezes the hose 3. In this way, under the rotation of the rotating shaft 26, the peristaltic pump can pressurize the fluid inside the pipeline. When the patient is not injected with suspended red blood cells, the entire heating device only needs to refrigerate the suspended red blood cells. At this time, the heating mechanism works normally, and the servo motor 30 corresponding to the peristaltic pump connected to the connecting tube 5 will rotate in the opposite direction, driving the threaded rod 34 to rotate in the opposite direction, so that the piston 35 moves toward the pressurized shell 2. At this time, under the action of negative pressure, the connecting rod 24 shrinks, and the squeezing roller 25 separates from the hose 3. In this way, the peristaltic pump cannot pressurize the suspended red blood cells in the connecting tube 5, and the suspended red blood cells can be refrigerated and stored separately.
[0051] In this embodiment, a control panel 41 is installed on the outer wall of the box 1. Since the refrigeration semiconductor 21 is used to quickly heat and refrigerate the suspended red blood cells, it is light in weight and can be used in field emergency scenarios. At the same time, a battery is used to power each electronic control component. In order to facilitate medical personnel to carry, such as Figure 7 As shown, a shoulder strap 40 is installed on the outer wall of the box body 1, so that in wartime, medical staff can carry the heating device to perform emergency blood transfusion on injured soldiers.
[0052] Working principle: When it is necessary to use the heating device to heat the suspended red blood cells, after adjusting the temperature on the control panel 41, the control processor (not marked in the figure) will open the solenoid valve 19 to allow the suspended red blood cells in the preservation box 15 to flow into the storage box 9 through the delivery tube 18. At this time, the two peristaltic pumps are working normally for pressurization. The control processor controls the battery to energize the refrigeration semiconductor 21 in the forward direction. The refrigeration semiconductor 21 generates heat at one end close to the connecting tube 5 and generates cold at the other end. The heating end heats the suspended red blood cells flowing through the connecting tube 5. At the end of the connecting tube 5, a temperature sensor (not marked in the figure) is provided. When the temperature sensor senses that the temperature of the outflowing suspended red blood cells reaches the specified temperature (37°C), the control processor will control the stepper motor 38 to rotate, so that the L-shaped channel 37 connects the connecting tube 5 and the liquid outlet tube 26, and the infusion bottle 11 / bag is placed at the position of the liquid outlet tube 26, and the red blood cells of the specified temperature can be filled. In addition, the liquid outlet tube 2 6 of this embodiment can also be directly connected to the infusion tube, so that the suspended red blood cells flowing out of the connecting tube 5 can be directly injected into the patient's body.
[0053] At the same time, the refrigeration end of the refrigeration semiconductor 21 will cool the water in the liquid outlet pipe 17, so that the water in the refrigerator 16 is always maintained in the range of 4-6°C.
[0054] If the injection is completed, the stepper motor 38 drives the rotating ball 39 to rotate, so that the connecting tube 5 is not connected with the return tube 2 and the outlet tube 2 6. If another injection is needed, the stepper motor 38 rotates to make the L-shaped channel 37 connect the connecting tube 5 with the return tube 2, so that the suspended red blood cells in the connecting tube 5 first return to the storage box 9, and then enter the connecting tube 5 for a complete heating process, so that the outflowing suspended red blood cells can be guaranteed to be around 37°C. In this process, when the suspended red blood cells pass through the spiral heating tube 10, the heat emitted can preheat the infusion bottle 11 / bag to avoid a large temperature change when the infusion bottle 11 or the infusion bag is loaded.
[0055] Example 2: A rapid heating device for suspended red blood cells for emergency use. The difference between this example and example 1 is that the heating mechanism has a different heating method. This example uses a single-stage compression refrigeration method to heat and refrigerate the suspended red blood cells. Figure 8As shown, the heating mechanism is mainly composed of two heat exchange sleeves 45, a connecting pipe 46 and a compressor 47 refrigeration system; the two heat exchange sleeves 45 are fixedly sleeved on the two connecting pipes 5, respectively, the two ends of the connecting pipe 46 are fixedly connected to the ends of the two heat exchange sleeves 45, and the side walls of the two heat exchange sleeves 45 are fixedly connected to the liquid inlet and liquid outlet of one of the peristaltic pumps, respectively; the heating end of the compressor 47 refrigeration system is located in the heat exchange sleeve 45, and the refrigeration end of the compressor 47 refrigeration system is located in the refrigerator 16;
[0056] The compressor 47 refrigeration system is mainly composed of a spiral tube 44, a coil 42, a throttling element and a compressor 47; the exhaust end of the compressor 47 is connected to the spiral tube 44, the air intake end of the compressor 47 is connected to the coil 42, and the liquid inlet end and the liquid outlet end of the throttling element are respectively connected to the spiral tube 44 and the coil 42; the throttling element adopts an electronic expansion valve 43, and the number of spiral tubes 44 is one or two. If there are two spiral tubes 44, a venturi liquid distributor is required to be set at the liquid inlet end of the spiral tube 44 so that the refrigerant can evenly enter the two spiral tubes 44. The refrigeration compression cycle of this embodiment adopts R32 refrigerant. The refrigerant of the refrigeration system absorbs heat in the coil 42, and then enters the compressor 47. The compressor 47 pressurizes the refrigerant into a high-temperature and high-pressure gas, and then enters the spiral tube 44, releasing this part of the heat into the water cycle, and then throttles through the electronic expansion valve 43 to become a low-temperature and low-pressure liquid refrigerant, and finally returns to the coil 42 to repeat the above functions.
[0057] The connection relationship between the peristaltic pump and the heat exchange sleeve 45 is as follows: Fig. 9 As shown, the peristaltic pump allows the water in the heat exchange sleeve 45 to flow so that it contacts with the spiral tube 44 for heat exchange, and the water then transfers the heat to the connecting tube 5 by heat conduction and heat convection, thereby achieving rapid heating of the flowing suspended red blood cells.
[0058] It should be emphasized that the heating mechanism has both heating and cooling ends. The heating end heats the inside of the connecting pipe 5, and the cooling end cools the inside of the refrigerator 16. Such heating mechanisms are all within the protection scope of this patent.
[0059] Embodiment 3: A rapid heating device for suspended red blood cells for emergency use. The difference between this embodiment and embodiment 1 is that the structure of the regulating unit is different. The regulating unit of this embodiment is as follows: Fig.10 and Fig.11As shown, the rotating shaft 26 is rotatably sleeved on the output shaft 20, and the adjustment unit is mainly composed of a transmission disc 50, a telescopic sleeve 48, a screw rod 51 and a servo motor 2 53; the transmission disc 50 is sleeved on the output shaft 20, and the transmission disc 50 and the output shaft 20 are connected in a spline manner, but the transmission disc 50 can translate along the length direction of the output shaft 20. An annular groove 49 is opened on the side wall of the transmission disc 50, and the transmission disc 50 can mesh with the opposite side wall of the rotating shaft 26; the servo motor 2 53 is fixedly installed on the inner side wall of the pressurized housing 2, the end of the screw rod 51 is fixedly connected to the output end of the servo motor 2 53, the telescopic sleeve 48 is sleeved on the screw rod 51, and the top protruding position of the telescopic sleeve 48 is located in the annular groove 49 and contacts with the transmission disc 50. When the transmission disc 50 is meshed with the side of the rotating shaft 26 , the rotational power of the output shaft 20 can be transmitted to the rotating shaft 26 . When the transmission disc 50 is separated from the rotating shaft 26 , the rotational power of the output shaft 20 will not be transmitted to the rotating shaft 26 .
[0060] When only the suspended red blood cells need to be refrigerated, the servo motor 2 53 drives the screw rod 51 to rotate, and the telescopic sleeve 48 drives the transmission plate 50 to move in a direction away from the rotating shaft 26 , so that the rotational power of the output shaft 20 cannot be transmitted to the rotating shaft 26 .
[0061] In this embodiment, in order to allow the adjustment unit to translate stably, a telescopic rod 52 is further installed on the side wall of the pressurized shell 2 , and the protruding position of the side wall of the telescopic rod 52 is also located in the annular groove 49 .
[0062] It should be noted that as long as the adjustment unit can control whether the squeezing roller 25 is squeezed with the hose 3, the structure of such an adjustment unit is within the protection scope of this patent.
[0063] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A device for rapidly heating suspended red blood cells for emergency use, comprising a housing (1), characterized in that: A storage box (9) and a refrigerator (16) are installed in the box body (1), a storage box (15) for storing suspended red blood cells is fixedly installed in the refrigerator (16), the top opening of the storage box (15) is located at the top of the box body (1), the refrigerator (16) is filled with liquid for cooling the storage box (15), and a delivery pipe (18) equipped with a solenoid valve (19) is arranged between the storage box (15) and the storage box (9); two peristaltic pumps are arranged in parallel in the box body (1), a driving mechanism is arranged between the two peristaltic pumps, and the driving mechanism can simultaneously drive the two peristaltic pumps to rotate in the same direction, and one of the peristaltic pumps can rotate in the same direction. The liquid inlet and liquid outlet of the peristaltic pump are both connected to a connecting pipe (5); the other end of the connecting pipe (5) connected to the liquid inlet of the peristaltic pump is connected to a storage box (9); the other end of the connecting pipe (5) connected to the liquid outlet of the peristaltic pump is used to output the suspended red blood cells to the outside of the box (1); heating mechanisms are installed on the two connecting pipes (5); the heating end of the heating mechanism is located on the connecting pipe (5) to directly heat the suspended red blood cells flowing through, and the cooling end of the heating mechanism is used to cool the liquid in the refrigerator (16); the liquid inlet and liquid outlet of another peristaltic pump are both connected to the heating mechanism, and the peristaltic pump is used to circulate the water of the heating mechanism.
2. The device for rapidly heating suspended red blood cells for emergency use according to claim 1, characterized in that: The heating mechanism comprises a liquid outlet pipe (17), a liquid return pipe (14), two connecting blocks (4) and two heating units; the ends of the liquid outlet pipe (17) and the liquid return pipe (14) are fixedly connected to the side wall of the refrigerator (16); the ends of the liquid outlet pipe (17) and the liquid return pipe (14) away from the refrigerator (16) are respectively connected to the liquid inlet end and the liquid outlet end of the peristaltic pump; one of the connecting blocks (4) is simultaneously sleeved on the connecting pipe (5) and the liquid outlet pipe (17), and the other connecting block (4) is simultaneously sleeved on the connecting pipe (5) and the liquid return pipe (14); the two heating units are both installed in the two connecting blocks (4), the heating ends of the two heating units are both located in the connecting pipe (5), the cooling end of one heating unit is located in the liquid outlet pipe (17), and the cooling end of the other heating unit is located in the liquid return pipe (14).
3. The device for rapidly heating suspended red blood cells for emergency use according to claim 2, characterized in that: The heating unit comprises two heat conducting plates (22), a plurality of refrigeration semiconductors (21) and a plurality of heat exchange rods (23). The plurality of refrigeration semiconductors (21) are arranged along the length direction of the connecting pipe (5). The two ends of the refrigeration semiconductors (21) are respectively fixedly connected to the two heat conducting plates (22). One of the heat conducting plates (22) is embedded in the side wall of the connecting pipe (5), and the other heat conducting plate (22) is embedded in the side wall of the liquid outlet pipe (17) or the liquid return pipe (14).
4. The device for rapidly heating suspended red blood cells for emergency use according to claim 1, characterized in that: The heating mechanism comprises two heat exchange sleeves (45), a connecting pipe (46) and a compressor (47) refrigeration system; the two heat exchange sleeves (45) are respectively fixedly sleeved on the two connecting pipes (5), the two ends of the connecting pipe (46) are respectively fixedly connected to the ends of the two heat exchange sleeves (45), and the side walls of the two heat exchange sleeves (45) are respectively fixedly connected to the liquid inlet end and the liquid outlet end of one of the peristaltic pumps; the heating end of the compressor (47) refrigeration system is located in the heat exchange sleeves (45), and the refrigeration end of the compressor (47) refrigeration system is located in the refrigerator (16); The compressor (47) refrigeration system comprises a spiral tube (44), a coil (42), a throttling element and a compressor (47); the exhaust end of the compressor (47) is connected to the spiral tube (44), the intake end of the compressor (47) is connected to the coil (42), and the liquid inlet end and the liquid outlet end of the throttling element are respectively connected to the spiral tube (44) and the coil (42).
5. The device for rapidly heating suspended red blood cells for emergency use according to claim 1, characterized in that: The end of the connecting pipe (5) connected to the liquid outlet of the peristaltic pump is also connected to a flow direction regulating valve, and the side wall of the flow direction regulating valve is also connected to a second liquid return pipe (8) and a second liquid outlet pipe (6), the end of the second liquid outlet pipe (6) away from the flow direction regulating valve is located outside the box (1), the end of the second liquid return pipe (8) away from the flow direction regulating valve is connected to a spiral heating pipe (10), and the end of the spiral heating pipe (10) away from the second liquid return pipe (8) is connected to a storage box (9); the flow direction regulating valve is used to adjust the flow direction of the suspended red blood cells in the connecting pipe (5); the box (1) is detachably provided with a cover (12) located directly above the spiral heating pipe (10).
6. The device for rapidly heating suspended red blood cells for emergency use according to claim 5, characterized in that: The flow direction regulating valve comprises a spherical shell (7), a rotating sphere (39) and a stepping motor (38); a connecting pipe (5), a second return pipe and a second liquid outlet pipe (6) are all fixedly connected to the side wall of the spherical shell (7); the rotating sphere (39) is located in the spherical shell (7); the stepping motor (38) is fixedly installed on the outer side wall of the spherical shell (7); the output end of the stepping motor (38) is fixedly connected to the side wall of the rotating sphere (39); an L-shaped channel (37) is opened in the rotating sphere (39); one end of the L-shaped channel (37) is always connected to the connecting pipe (5), and the other end can be connected to the second return pipe and the second liquid outlet pipe (6) respectively under the drive of the stepping motor (38).
7. The device for rapidly heating suspended red blood cells for emergency use according to claim 1, characterized in that: The driving mechanism comprises a driving motor (32) and two transmission units; the output end of the driving motor (32) is connected to one of the transmission units, the power output ends of the two transmission units are respectively fixedly connected to the power input ends of the peristaltic pump, and the two transmission units are meshed; The transmission unit comprises a transmission shaft (28), a spur gear (29), an output shaft (20) and two meshing bevel gears (27); the two bevel gears (27) are respectively fixedly sleeved on the transmission shaft (28) and the output shaft (20), and the spur gear (29) is also fixedly sleeved on the transmission shaft (28); the spur gears (29) of the two transmission units are meshed with each other; the end of the transmission shaft (28) of one of the transmission units is fixedly connected to the power output end of the driving motor (32); and the end of the output shaft (20) is fixedly connected to the rotation axis of the peristaltic pump.
8. The device for rapidly heating suspended red blood cells for emergency use according to claim 7, characterized in that: The peristaltic pump comprises a pressurizing shell (2), a hose (3), a rotating shaft (26) and a plurality of pressurizing devices, wherein the plurality of pressurizing devices are installed on the rotating side wall of the rotating shaft (26) with equal arc length, and the rotating shaft (26) is sleeved on the output shaft (20); the interior of the pressurizing shell (2) is a semicircular cavity with an opening on one side, the hose (3) is attached to the inner arc wall surface of the pressurizing shell (2), and the two ends of the hose (3) are respectively connected to two connecting pipes (5); the pressurizing device can squeeze the hose (3); The pressurizing device comprises an extrusion roller (25), a connecting rod (24) and an adjusting unit; the two ends of the connecting rod (24) are respectively connected to the rotating shaft (26) and the extrusion roller (25); the extrusion roller (25) can extrude the hose (3); the adjusting unit is installed on the pressurizing housing (2) and is used to adjust the extrusion state between the extrusion roller (25) and the hose (3).
9. The device for rapidly heating suspended red blood cells for emergency use according to claim 8, characterized in that: The rotating shaft (26) is a hollow rotating shaft (26), and the rotating shaft (26) is fixedly sleeved on the output shaft (20); the connecting rod (24) is a telescopic connecting rod (24), and the interior of the connecting rod (24) is connected to the interior of the rotating shaft (26); the adjusting unit comprises a connecting cylinder (36), a threaded rod (34), a piston (35) and a servo motor (30); one end of the connecting cylinder (36) is fixedly connected to the inner wall of the pressurized shell (2), and the other end of the connecting cylinder (36) is rotatably connected to the axis center of the hollow rotating shaft (26) and is connected to the interior of the rotating shaft (26); the servo motor (30) is fixedly installed on the outer wall of the pressurized shell (2), the output end of the servo motor (30) is fixedly connected to the end of the threaded rod (34), the piston (35) is sleeved on the threaded section of the threaded rod (34), and the piston (35) is in sealing and sliding contact with the inner wall of the connecting cylinder (36).
10. The device for rapidly heating suspended red blood cells for emergency use according to claim 9, characterized in that: The rotating shaft (26) is rotatably sleeved on the output shaft (20), and the adjustment unit comprises a transmission disc (50), a telescopic sleeve (48), a screw rod (51) and a second servo motor (53); the transmission disc (50) is slidably sleeved on the output shaft (20), an annular groove (49) is provided on the side wall of the transmission disc (50), and the transmission disc (50) and the opposite side wall of the rotating shaft (26) can be meshed; the second servo motor (53) is fixedly installed on the inner side wall of the pressurized housing (2), the end of the screw rod (51) is fixedly connected to the output end of the second servo motor (53), the telescopic sleeve (48) is sleeved on the screw rod (51), and the top protruding position of the telescopic sleeve (48) is located in the annular groove (49) and contacts with the transmission disc (50).
Citation Information
Patent Citations
Apparatus for heating blood or another physiological fluid
CN1620319A
Rapid heater applied to first-aid suspended red blood cells
CN214633199U