Medicinal preparation pharmacological experiment dissolving device
By designing a pharmacological experimental dissolution device for drug preparations that include grinding and stirring functions, the problem of artificial breakage of larger drugs in the prior art is solved, and rapid grinding and dissolution of drugs is achieved, improving work efficiency and avoiding waste of drugs.
Patent Information
- Application Number
- CN202411932157.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-26
- Publication Date
- 2025-03-04
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
When dissolving large solid drugs, existing dissolution devices require manual crushing and processing, resulting in low work efficiency, waste of time and partial waste of medicines.
A pharmacological experimental dissolution device for pharmaceutical preparations was designed, including a workbench, a circular mounting plate, a dissolution barrel, a mounting box and a grinding mechanism. The drug is ground through the first driving motor driving the grinding mechanism, the second driving motor driving the dissolution drum and the stirring rod to rotate, and the servo motor drives the circular mounting plate to rotate, so that the dissolution drum and the stirring rod can rotate, realizing rapid grinding and dissolution of the drug.
There is no need to manually crush drugs, which significantly saves time, improves dissolution efficiency, avoids waste of drugs, and achieves faster dissolution of drugs.
Smart Images

Figure CN119549012A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of pharmacological experiments, in particular to a drug preparation pharmacological experiment dissolving device. Background Art
[0002] Pharmacological experiments are an important process in the process of drug preparation. In the pharmacological experiments of drug preparations, the dissolving device plays a vital role. For example, the dissolving device for pharmaceutical experiments proposed in the patent with application number 201921823607.4 includes a base, a driving motor and a connecting shaft. One side of the connecting shaft is fixedly connected with a fixed disk, and the upper surface of the fixed disk is fixedly connected with a placement shell. A conical flask is arranged inside the placement shell, and the upper surface of the placement shell is movably connected with a connecting cover, and the upper surface of the connecting cover is fixedly connected with a fastening device. The dissolving device for pharmaceutical experiments, through the arrangement of the placement shell and the conical flask, when dissolving the reagent in the conical flask, can place the conical flask containing the reagent in the placement shell, and then use the connecting cover to fix the upper half of the conical flask, and then drive the connecting shaft through the rotation of the driving motor, thereby driving the fixed disk and the conical flask placed on the surface and containing the reagent to be dissolved to rotate, accelerating the dissolution of the drug, improving the work efficiency of the experimenter, and increasing the efficiency of pharmaceutical experiments.
[0003] When dissolving some larger solid medicines, the existing dissolution device needs to be manually crushed in advance, otherwise it will take a longer time to fully dissolve, resulting in low work efficiency. Manual operation will also waste time and cause partial waste of medicines. Therefore, improvements are made to this, and a drug preparation pharmacology experiment dissolution device is proposed. Summary of the invention
[0004] In view of the deficiencies in the prior art, the present invention provides a drug preparation pharmacological experiment dissolution device, which solves the problem that when the dissolution device is used to dissolve some larger solid medicines, it needs to manually crush them in advance, otherwise it will take a longer time to fully dissolve, resulting in low work efficiency. Manual operation will also waste time and cause partial waste of medicines.
[0005] To achieve the above object, the technical solution adopted by the present invention is:
[0006] A drug preparation pharmacological experiment dissolution device comprises a workbench, a circular mounting plate is rotatably mounted on the upper surface of the workbench, a dissolution barrel is movably mounted on the upper surface of the circular mounting plate, side panels are mounted on both sides of the upper surface of the workbench, an installation box is arranged between the two side panels, an adjustment mechanism for controlling the movement of the installation box is arranged on one side of the side panel, and a grinding mechanism is arranged inside the installation box.
[0007] Preferably, a first circular groove is opened on the upper surface of the workbench, a servo motor is installed on the lower surface of the workbench, the output end of the servo motor is arranged inside the first circular groove and the end is fixedly connected to the center of the lower surface of the circular mounting plate.
[0008] Preferably, a limiting block is provided on the outer surface of the circular mounting plate, a limiting groove cooperating with the limiting block is provided on the inner wall of the first circular groove, a second circular groove is provided on the upper surface of the circular mounting plate, a clamping groove is provided on the inner wall of the second circular groove, and a clamping block cooperating with the clamping groove is provided on the bottom of the outer surface of the dissolving barrel.
[0009] Preferably, the grinding mechanism includes a mounting frame, the mounting frame is mounted on one end surface of the mounting box, a first driving motor is mounted on the one end surface of the mounting frame, and two first rotating rods are rotatably mounted on the one end surface of the mounting frame.
[0010] Preferably, one end of each of the first rotating rods is rotatably disposed on an end surface of the mounting box, one end of one of the first rotating rods is fixedly connected to the output end of the first driving motor, and a driving gear is fixedly mounted on the rod body of each of the first rotating rods.
[0011] Preferably, second rotating rods are rotatably installed on both sides of one end surface of the mounting frame, a driven gear is fixedly installed on the rod body of each of the second rotating rods, the two driving gears are meshed with each other, and the two driving gears are also respectively meshed with the driven gears, and a grinding roller is installed at one end of each of the second rotating rods located inside the mounting box, and one end of the grinding roller is rotatably set on the inner wall of one end of the mounting box.
[0012] Preferably, a mounting groove is provided on one side surface of each of the side panels, and the adjustment mechanism includes a second drive motor, which is installed on the top of one of the side panels, and an adjustment screw is installed at the output end of the second drive motor.
[0013] Preferably, one end of the adjusting screw rod is rotatably arranged on the bottom inner wall of the mounting groove at a corresponding position, a screw rod sleeve is movably installed on the rod body of the adjusting screw rod, and a sliding rod is installed inside the mounting groove away from the adjusting screw rod.
[0014] Preferably, a sliding block is slidably provided on the rod body of the sliding rod, and a connecting plate is installed at one end of the sliding block and the screw sleeve, and one end of the two connecting plates is respectively installed on the two end surfaces of the installation box.
[0015] Preferably, through grooves are provided on the upper and lower end surfaces of the installation box, a plurality of first stirring rods are evenly distributed on the inner wall of the dissolving barrel, a mounting rod is rotatably installed on one side of the lower surface of the installation box, and a plurality of second stirring rods are evenly distributed on the rod body of the installation rod.
[0016] Compared with the prior art, the present invention has the following beneficial effects:
[0017] 1. Driven by the first driving motor, under the meshing action between the two driving gears and the driven gear, the two second rotating rods can be driven to rotate in opposite directions, and the two grinding rollers rotate in opposite directions to grind the medicines. When dissolving large volumes of medicines, there is no need for manual crushing, which saves time and can effectively avoid the waste caused by manual crushing of medicines. The ground medicines can also be dissolved faster.
[0018] 2. Driven by the servo motor, the dissolving barrel and the first stirring rod inside can be rotated accordingly. During the rotation of the first stirring rod, the end of the first stirring rod will contact the second stirring rod. The mounting rod is rotated so that the first stirring rod can push the second stirring rod to rotate around the mounting rod as the axis during the rotation, thereby having a larger range, which can effectively speed up the dissolution of the medicine and is more efficient. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;
[0020] Figure 2 is a side view of the present invention;
[0021] Figure 3 It is a front view of the present invention;
[0022] Figure 4 For the present invention Figure 2 Schematic diagram of the three-dimensional structure of the cross section at AA in the middle;
[0023] Figure 5 For the present invention Figure 3 Schematic diagram of the three-dimensional structure of the cross section at BB in the middle;
[0024] Figure 6 For the present invention Figure 1 Enlarged view of center C.
[0025] In the figure: 1. workbench; 101. servo motor; 102. first circular groove; 1021. limit groove; 2. circular mounting plate; 201. second circular groove; 202. slot; 203. limit block; 3. dissolving barrel; 301. block; 302. first stirring rod; 4. side plate; 401. mounting groove; 5. mounting box; 501. through groove; 502. mounting rod; 503. second stirring rod; 6. grinding mechanism; 601. mounting frame; 602. first driving motor; 603. first rotating rod; 604. driving gear; 605. second rotating rod; 606. driven gear; 607. grinding roller; 7. adjusting mechanism; 701. second driving motor; 702. adjusting screw rod; 703. screw rod sleeve; 704. sliding rod; 705. sliding block; 706. connecting plate. DETAILED DESCRIPTION
[0026] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.
[0027] like Figure 1 As shown, a drug preparation pharmacological experiment dissolution device includes a workbench 1, a circular mounting plate 2 is rotatably mounted on the upper surface of the workbench 1, a dissolution barrel 3 is movably mounted on the upper surface of the circular mounting plate 2, side panels 4 are mounted on both sides of the upper surface of the workbench 1, an installation box 5 is arranged between the two side panels 4, an adjustment mechanism 7 for controlling the movement of the installation box 5 is arranged on one side of the side panel 4, and a grinding mechanism 6 is arranged inside the installation box 5.
[0028] like Figure 2 , Figure 4 As shown, a first circular groove 102 is provided on the upper surface of the workbench 1, a servo motor 101 is installed on the lower surface of the workbench 1, the output end of the servo motor 101 is arranged inside the first circular groove 102 and the end is fixedly connected to the center of the lower surface of the circular mounting plate 2, a limiting block 203 is provided on the outer surface of the circular mounting plate 2, a limiting groove 1021 cooperating with the limiting block 203 is provided on the inner wall of the first circular groove 102, a second circular groove 201 is provided on the upper surface of the circular mounting plate 2, a card slot 202 is provided on the inner wall of the second circular groove 201, and a card block 301 cooperating with the card slot 202 is provided on the bottom of the outer surface of the dissolving barrel 3.
[0029] Through the cooperation between the card block 301 and the card slot 202, the dissolving barrel 3 can be installed, making the taking and placing operation more convenient, and the dissolving barrel 3 can also be rotated following the circular mounting plate 2. Through the cooperation between the limit block 203 and the limit slot 1021, the circular mounting plate 2 is rotatably set inside the first circular groove 102.
[0030] like Figure 3 , Figure 4 , Figure 5 , Figure 6 As shown, the grinding mechanism 6 includes a mounting frame 601, which is mounted on one end surface of the mounting box 5, a first driving motor 602 is mounted on one end surface of the mounting frame 601, two first rotating rods 603 are rotatably mounted on one end surface of the mounting box 5, one end of each first rotating rod 603 is rotatably set on one end surface of the mounting box 5, one end of one of the first rotating rods 603 is fixedly connected to the output end of the first driving motor 602, a driving gear 604 is fixedly mounted on the rod body of each first rotating rod 603, second rotating rods 605 are rotatably mounted on both sides of one end surface of the mounting frame 601, a driven gear 606 is fixedly mounted on the rod body of each second rotating rod 605, the two driving gears 604 are meshed with each other, and the two driving gears 604 are also respectively meshed with the driven gear 606, and a grinding roller 607 is mounted on one end of each second rotating rod 605 located inside the mounting box 5, and one end of the grinding roller 607 is rotatably set on the inner wall of one end of the mounting box 5.
[0031] Through the meshing between the driving gear 604 and the driven gear 606, when the first driving motor 602 is driven, the rotation direction of the two grinding rollers 607 can be controlled, so that the medicine can be ground. There is no need to manually crush large volumes of medicines. The medicines ground into powder can also be dissolved faster, which can effectively shorten the time and improve the dissolution efficiency.
[0032] like Figure 4 As shown, a mounting groove 401 is provided on one side surface of each side plate 4, and the adjusting mechanism 7 includes a second driving motor 701, and the second driving motor 701 is installed on the top of one of the side plates 4, and an adjusting screw rod 702 is installed at the output end of the second driving motor 701, and one end of the adjusting screw rod 702 is rotatably set on the bottom inner wall of the mounting groove 401 at the corresponding position, and a screw rod sleeve 703 is movably installed on the rod body of the adjusting screw rod 702, and a sliding rod 704 is installed inside the mounting groove 401 away from the adjusting screw rod 702, and a sliding block 705 is slidably set on the rod body of the sliding rod 704, and one end of the sliding block 705 and the screw rod sleeve 703 are both installed with connecting plates 706, and one end of the two connecting plates 706 are respectively installed on the two end surfaces of the mounting box 5.
[0033] By adjusting the meshing transmission between the screw rod 702 and the screw rod sleeve 703, the installation box 5 can be controlled to move under the drive of the second drive motor 701, which is convenient for taking and placing the dissolving barrel 3. Through the sliding cooperation between the sliding block 705 and the sliding rod 704, the moving trajectory of the installation box 5 can be limited, making it more stable during the movement.
[0034] like Figure 4 As shown, through grooves 501 are provided on the upper and lower end surfaces of the installation box 5, a plurality of first stirring rods 302 are evenly distributed on the inner wall of the dissolving barrel 3, a mounting rod 502 is rotatably installed on one side of the lower surface of the installation box 5, and a plurality of second stirring rods 503 are evenly distributed on the rod body of the installation rod 502.
[0035] When the first stirring rod 302 rotates with the dissolving barrel 3, its end will push the second stirring rod 503 to rotate, so that it can stir over a larger range, fully stir the medicine and make it dissolve faster. The installation rod 502 is rotatably set at the bottom of the installation box 5 and can move with the installation box 5.
[0036] The working principle of this drug preparation pharmacology experiment dissolution device:
[0037] When in use, the dissolving barrel 3 is installed into the inside of the second circular groove 201 through the cooperation of the block 301 and the slot 202, and the solvent is introduced into the inside of the dissolving barrel 3, and then the adjusting screw rod 702 is driven to rotate by the second driving motor 701. Under the meshing action between the adjusting screw rod 702 and the screw rod sleeve 703, the installation box 5 can be controlled to move up and down, and the installation box 5 is moved down to a position closer to the top of the dissolving barrel 3, so that the installation rod 502 and the second stirring rod 503 are located inside the dissolving barrel 3, and one of the first rotating rods 603 is driven to rotate by the first driving motor 602. Under the meshing action between the two driving gears 604 and the driven gear 606, the two second rotating rods 605 can be driven to rotate in the opposite direction, and the medicine can be put into between the two grinding rollers 607 through the upper through slot 501. The two grinding rollers 607 rotate in opposite directions to grind the medicine. The powder will fall into the interior of the dissolving barrel 3 through the through groove 501 on the lower side. When dissolving a large volume of medicine, there is no need for manual crushing, which saves time and can effectively avoid the waste caused by manual crushing of medicine. The servo motor 101 drives the circular mounting plate 2 to rotate, so that the dissolving barrel 3 and the first stirring rod 302 inside rotate accordingly. During the rotation of the first stirring rod 302, the end portion will contact the second stirring rod 503. The mounting rod 502 is rotated so that the first stirring rod 302 can push the second stirring rod 503 to rotate around the mounting rod 502 as the axis during the rotation, thereby having a larger range, which can effectively speed up the dissolution speed of the medicine and is more efficient. After the dissolution is completed, the mounting box 5 is moved up by the drive of the second drive motor 701, so that the mounting rod 502 is moved out of the dissolving barrel 3, making it convenient to remove the dissolving barrel 3.
[0038] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not limitations on the implementation methods of the present invention. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made on the basis of the above description. It is impossible to list all the implementation methods here. All obvious changes or modifications derived from the technical solution of the present invention are still within the protection scope of the present invention.
Claims
1. A drug preparation pharmacological experiment dissolution device, comprising a workbench (1), characterized in that: A circular mounting plate (2) is rotatably mounted on the upper surface of the workbench (1), a dissolving barrel (3) is movably mounted on the upper surface of the circular mounting plate (2), side plates (4) are mounted on both sides of the upper surface of the workbench (1), an installation box (5) is arranged between the two side plates (4), an adjustment mechanism (7) for controlling the movement of the installation box (5) is arranged on one side of the side plate (4), and a grinding mechanism (6) is arranged inside the installation box (5).
2. A drug preparation pharmacological experiment dissolution device according to claim 1, characterized in that: The upper surface of the workbench (1) is provided with a first circular groove (102), and a servo motor (101) is installed on the lower surface of the workbench (1). The output end of the servo motor (101) is arranged inside the first circular groove (102) and the end is fixedly connected to the center of the lower surface of the circular mounting plate (2).
3. A drug preparation pharmacological experiment dissolution device according to claim 2, characterized in that: A limiting block (203) is arranged on the outer surface of the circular mounting plate (2); a limiting groove (1021) cooperating with the limiting block (203) is provided on the inner wall of the first circular groove (102); a second circular groove (201) is provided on the upper surface of the circular mounting plate (2); a clamping groove (202) is provided on the inner wall of the second circular groove (201); and a clamping block (301) cooperating with the clamping groove (202) is provided on the bottom of the outer surface of the dissolving barrel (3).
4. A drug preparation pharmacological experiment dissolution device according to claim 1, characterized in that: The grinding mechanism (6) comprises a mounting frame (601), the mounting frame (601) being mounted on one end surface of the mounting box (5), a first driving motor (602) being mounted on one end surface of the mounting frame (601), and two first rotating rods (603) being rotatably mounted on one end surface of the mounting frame (601).
5. A drug preparation pharmacological experiment dissolution device according to claim 4, characterized in that: One end of each of the first rotating rods (603) is rotatably mounted on an end surface of the mounting box (5), one end of one of the first rotating rods (603) is fixedly connected to the output end of the first driving motor (602), and a driving gear (604) is fixedly mounted on the rod body of each of the first rotating rods (603).
6. A drug preparation pharmacological experiment dissolution device according to claim 5, characterized in that: Second rotating rods (605) are rotatably mounted on both sides of the surface of one end of the mounting frame (601); a driven gear (606) is fixedly mounted on the rod body of each of the second rotating rods (605); the two driving gears (604) are meshed with each other; the two driving gears (604) are also respectively meshed with the driven gears (606); a grinding roller (607) is mounted on one end of each of the second rotating rods (605) located inside the mounting box (5); one end of the grinding roller (607) is rotatably mounted on the inner wall of one end of the mounting box (5).
7. A drug preparation pharmacological experiment dissolution device according to claim 1, characterized in that: A mounting groove (401) is provided on one side surface of each of the side panels (4), and the adjustment mechanism (7) comprises a second drive motor (701), the second drive motor (701) is installed on the top of one of the side panels (4), and an adjustment screw rod (702) is installed at the output end of the second drive motor (701).
8. A drug preparation pharmacological experiment dissolution device according to claim 7, characterized in that: One end of the adjusting screw rod (702) is rotatably arranged on the bottom inner wall of the mounting groove (401) at a corresponding position, a screw rod sleeve (703) is movably installed on the rod body of the adjusting screw rod (702), and a sliding rod (704) is installed inside the mounting groove (401) away from the adjusting screw rod (702).
9. A drug preparation pharmacological experiment dissolution device according to claim 8, characterized in that: A sliding block (705) is slidably provided on the rod body of the sliding rod (704), and one end of the sliding block (705) and the screw rod sleeve (703) are both installed with a connecting plate (706), and one end of the two connecting plates (706) are respectively installed on the two end surfaces of the installation box (5).
10. A drug preparation pharmacological experiment dissolution device according to claim 1, characterized in that: The upper and lower surfaces of the installation box (5) are penetrated by through grooves (501), the inner wall of the dissolving barrel (3) is evenly distributed with a plurality of first stirring rods (302), a mounting rod (502) is rotatably mounted on one side of the lower surface of the installation box (5), and a plurality of second stirring rods (503) are evenly distributed on the rod body of the installation rod (502).
Citation Information
Patent Citations
Dissolving device for pharmaceutical experiments
CN210874872U
Cited By
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