Traditional Chinese medicine preparation for treating gynecological inflammation and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine preparation for treating gynecological inflammation and a preparation method thereof.The traditional Chinese medicine preparation comprises a component A and a component B. The component A is prepared from cockscomb, motherwort, radix scrophulariae, radix rehmanniae recen, deer glue, turtle glue, processed ginger, bamboo charcoal powder, cortex phellodendri extract, lotus root extract, sodium alginate, honey and sesame oil; the component B comprises the following raw materials: fistular onion stalk, pepper, processed coptis chinensis, radix sophorae flavescentis and sargentgloryvine stem; the invention relates to the technical field of traditional Chinese medicine preparations. According to the traditional Chinese medicine preparation for treating gynecological inflammation and the preparation method thereof, through cooperation of the component A and the component B, the traditional Chinese medicine preparation not only has the advantages of sterilization and inflammation diminishing, but also is free of irritation through compatibility of pure traditional Chinese medicines, can nourish the vagina and provide effective support for recovery of vaginal flora, can effectively adsorb secretions in the vagina, and can effectively treat gynecological inflammation. Convenience is provided for vagina cleaning, and peculiar smell and pruritus at the vagina are effectively eliminated.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for gynecological inflammation and a preparation method thereof. Background Art

[0002] Gynecological diseases refer to diseases of the female reproductive system. They are common and frequently occurring diseases in women, including vulvar diseases, vaginal diseases, uterine diseases, fallopian tube diseases, ovarian diseases, etc. Leucorrhea is vaginal discharge, which is a mixture of vaginal mucosal exudates, cervical glands and endometrial gland secretions. Abnormal leucorrhea, as a common gynecological inflammation, refers to an abnormal increase in the amount of vaginal secretions in women, and is often accompanied by odor, itching, etc., which brings great discomfort and distress to patients.

[0003] At present, the treatment of gynecological inflammation is generally based on external use of Western medicine. Most of these drugs contain antibiotics or chemical disinfectants such as metronidazole and clotrimazole. Long-term use will cause certain damage to organs such as the liver and kidneys, and it is easy for pathogens to develop drug resistance, destroy the mutual restraint relationship between vaginal flora and cause dysbacteriosis, destroy the self-cleaning and defense ability of the vagina, cause repeated illness, and cannot be completely eradicated. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a traditional Chinese medicine preparation for gynecological inflammation and a preparation method thereof, which solves the problems raised in the above-mentioned background technology.

[0005] To achieve the above objectives, the present invention is implemented through the following technical solutions:

[0006] In one aspect, a traditional Chinese medicine preparation for gynecological inflammation comprises:

[0007] Component A, wherein the raw materials of component A include, by weight: 15-32 parts of cockscomb, 10-25 parts of motherwort, 3-5 parts of Scrophularia, 15-25 parts of Rehmannia root, 3-8 parts of deer glue, 3-8 parts of tortoise glue, 10-18 parts of processed ginger, 5-12 parts of bamboo charcoal powder, 8-18 parts of Phellodendron chinense extract, 7-16 parts of lotus root extract, 15-25 parts of sodium alginate, 20-35 parts of honey and 3-5 parts of sesame oil;

[0008] Component B, the raw materials of component B include 5-15 parts of green onion, 5-10 parts of prickly ash, 20-50 parts of processed coptis root, 3-10 parts of sophora flavescens and 3-5 parts of red safflower by weight.

[0009] The present invention is further configured as follows: the ginger processed product comprises peeled old ginger paste and ginger juice, wherein the peeled old ginger paste and ginger juice comprise 3:5 in weight ratio;

[0010] The peeled old ginger paste is prepared by peeling old ginger and then crushing and squeezing it to obtain ginger juice. The filtered solid ginger powder is immersed in water for 15-30 minutes, and then taken out and dried to obtain the peeled old ginger paste.

[0011] The present invention is further configured as follows: the lotus root extract comprises lotus root silk, lotus root powder and lotus leaf, wherein the lotus root silk, lotus root powder and lotus leaf are in a weight ratio of 1:25:65;

[0012] The lotus leaf is obtained by grinding the naturally dried lotus leaf into powder and sifting through a 200-mesh sieve.

[0013] The present invention is further configured as follows: the processed Rhizoma Coptidis comprises Rhizoma Coptidis and yellow wine, wherein the weight ratio of the Rhizoma Coptidis to the yellow wine is 1:8;

[0014] The coptis root is soaked in rice wine for at least 24 hours.

[0015] Among them, cockscomb has the properties of clearing wind and reducing fever, motherwort has the properties of eliminating water, promoting blood circulation, regulating menstruation and detoxifying, and Scrophularia has the effects of clearing heat, cooling blood and detoxifying. Combined with the effects of Rehmannia root on clearing heat, promoting fluid production and nourishing yin, it can achieve the effects of vaginal detoxification and nourishing.

[0016] Among them, bamboo charcoal powder has good adsorption and bactericidal effects. It is combined with ginger preparations to reduce the coldness of component A and provide a variety of trace elements to provide support for the self-healing of vaginal flora.

[0017] In addition, the advantages of deer glue in reducing swelling and warding off evil spirits combined with tortoise glue in nourishing yin and moistening dryness provide convenience for the preparation of pills and can further enhance the nourishing effect on the vagina.

[0018] Among them, lotus root powder increases the viscosity of the medicine, lotus root silk can delay aging, improve skin firmness, and further improve the stability of the pills. Combined with the antibacterial, anti-inflammatory and antioxidant properties of lotus leaves, it provides a maintenance effect for the vagina.

[0019] On the other hand, the present invention also discloses a method for preparing a Chinese medicine preparation for gynecological inflammation, which specifically comprises the following steps:

[0020] Step 1, weighing raw materials: according to the weight ratio of component A, weigh cockscomb, motherwort, Scrophularia, raw rehmannia, deer glue, tortoise glue, ginger processing, bamboo charcoal powder, phellodendron extract, lotus root extract, sodium alginate, honey and sesame oil as the raw materials of component A;

[0021] Weigh scallion, Zanthoxylum bungeanum, processed Coptis chinensis, Sophora flavescens and Caulis Scutellariae in accordance with the weight ratio of component B as raw materials of component B;

[0022] Step 2, preparation of component A: put cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue and tortoise glue in a medicine pot, add ten times the amount of water and boil for 3-5 hours;

[0023] When the amount of water is reduced to three times, add the processed ginger and Phellodendron amurense extract, keep the temperature at 45°C for 30 minutes, remove the residue, add bamboo charcoal powder and lotus root extract, and stir at 400r / min for 10-15 minutes. During the process, keep the temperature of the medicine tank at 30°C.

[0024] Add sodium alginate, honey and sesame oil, stir at 600 r / min for 15-20 min at a constant temperature of 25°C to obtain an ointment;

[0025] After rolling into pills, the preparation of component A is completed;

[0026] Step 3, preparation of component B: add scallion, pepper, processed coptis root, sophora flavescens and red safflower into a medicine pot, add five times the amount of water and soak for 30 minutes, bring to a boil over high heat, then simmer for 15-20 minutes over low heat, pour out the liquid medicine to obtain the second lotion;

[0027] Add three times the amount of water again, bring to a boil over high heat, then simmer for 15-20 minutes over low heat, pour out the liquid, and obtain the first lotion;

[0028] After the first lotion and the second lotion are cooled to room temperature, they are sealed and packed in bags for storage, thereby completing the preparation of component B.

[0029] The present invention provides a Chinese medicine preparation for gynecological inflammation and a preparation method thereof. It has the following beneficial effects:

[0030] The present invention not only has the advantages of sterilization and anti-inflammation through the combination of component A and component B, but also achieves nourishment to the vagina through the compatibility of pure Chinese medicine, is non-irritating, provides effective support for the recovery of vaginal flora, can effectively absorb secretions in the vagina, facilitate vaginal cleaning, and effectively eliminate odor and itching in the vagina. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 It is a schematic diagram of the structure of the present invention. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0033] See also Figure 1 , the embodiment of the present invention provides the following technical solutions:

[0034] A Chinese medicine preparation for gynecological inflammation, comprising component A for internal administration, wherein the raw materials of component A include: cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue, tortoise glue, processed ginger, bamboo charcoal powder, Phellodendron amurense extract, lotus root extract, sodium alginate, honey and sesame oil, wherein the processed ginger includes peeled ginger paste and ginger juice, wherein the peeled ginger paste and ginger juice are in a weight ratio of 3:5;

[0035] Peeled ginger paste is made by peeling the ginger, crushing and squeezing it, and soaking the filtered solid ginger in water for 15-30 minutes, then taking it out and drying it to obtain peeled ginger paste.

[0036] Ginger juice is the juice squeezed from fresh ginger after peeling it.

[0037] The lotus root extract comprises lotus root silk, lotus root powder and lotus leaf, wherein the lotus root silk, lotus root powder and lotus leaf are in a weight ratio of 1:25:65;

[0038] The lotus leaf is obtained by grinding the naturally dried lotus leaf into powder and sifting through a 200-mesh sieve;

[0039] Lotus root silk is short silk of 1-2mm.

[0040] It also includes a cleaning liquid component B, the raw materials of component B include scallion, pepper, processed coptis root, sophora flavescens and red safflower, among which the processed coptis root includes coptis root and rice wine, the weight ratio of coptis root and rice wine is 1:8, and the coptis root is soaked in the rice wine for at least 24 hours.

[0041] Embodiment 1: A method for preparing a Chinese medicine preparation for gynecological inflammation, comprising the following steps:

[0042] Step 1, weighing raw materials: according to the weight ratio of component A, cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue, tortoise glue, ginger preparation, bamboo charcoal powder, Phellodendron extract, lotus root extract, sodium alginate, honey and sesame oil are weighed as raw materials of component A, wherein the weight ratio of component A includes: 32:25:5:25:8:8:18:12:18:16:25:35:5;

[0043] Weigh scallion, Zanthoxylum bungeanum, processed coptis root, sophora flavescens and red safflower according to the weight ratio of component B as raw materials of component B, wherein the weight ratio of component B includes: 15:10:50:10:5;

[0044] Step 2, preparation of component A: put cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue and tortoise glue in a medicine pot, add ten times the amount of water and boil for 3-5 hours;

[0045] When the amount of water is reduced to three times, add the processed ginger and Phellodendron amurense extract, keep the temperature at 45°C for 30 minutes, remove the residue, add bamboo charcoal powder and lotus root extract, and stir at 400r / min for 15 minutes. During the process, keep the temperature of the medicine tank at 30°C.

[0046] Sodium alginate, honey and sesame oil were added, and stirred at 600 r / min for 20 min at a constant temperature of 25°C to obtain an ointment;

[0047] After rolling into pills, the preparation of component A is completed;

[0048] Step 3, preparation of component B: add scallion, pepper, processed coptis root, sophora flavescens and red safflower into a medicine pot, add five times the amount of water and soak for 30 minutes, bring to a boil over high heat, then simmer for 20 minutes over low heat, pour out the liquid medicine to obtain a second lotion;

[0049] Add three times the amount of water again, bring to a boil over high heat, then simmer for 20 minutes over low heat, pour out the liquid, and obtain the first lotion;

[0050] After the first lotion and the second lotion are cooled to room temperature, they are sealed and packed in bags for storage, thereby completing the preparation of component B.

[0051] Embodiment 2: A Chinese medicine preparation for gynecological inflammation and a preparation method thereof, specifically comprising the following steps:

[0052] Step 1, weighing raw materials: according to the weight ratio of component A, cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue, tortoise glue, ginger preparation, bamboo charcoal powder, Phellodendron extract, lotus root extract, sodium alginate, honey and sesame oil are weighed as raw materials of component A, wherein the weight ratio of component A includes: 26:18:4:20:6:6:14:9:12:13:20:15:4;

[0053] Weigh scallion, Zanthoxylum bungeanum, processed coptis root, sophora flavescens and red safflower according to the weight ratio of component B as raw materials of component B, wherein the weight ratio of component B includes: 10:9:35:8:4;

[0054] Step 2, preparation of component A: put cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue and tortoise glue in a medicine pot, add ten times the amount of water and boil for 3-5 hours;

[0055] When the amount of water is reduced to three times, add the processed ginger and Phellodendron amurense extract, keep the temperature at 45°C for 30 minutes, remove the residue, add bamboo charcoal powder and lotus root extract, and stir at 400r / min for 12 minutes. During the process, keep the temperature of the medicine tank at 30°C.

[0056] Sodium alginate, honey and sesame oil were added, and stirred at 600 r / min for 20 min at a constant temperature of 25°C to obtain an ointment;

[0057] After rolling into pills, the preparation of component A is completed;

[0058] Step 3, preparation of component B: add scallion, pepper, processed coptis root, sophora flavescens and red safflower into a medicine pot, add five times the amount of water and soak for 30 minutes, bring to a boil over high heat, then simmer for 20 minutes over low heat, pour out the liquid medicine to obtain a second lotion;

[0059] Add three times the amount of water again, bring to a boil over high heat, then simmer for 20 minutes over low heat, pour out the liquid, and obtain the first lotion;

[0060] After the first lotion and the second lotion are cooled to room temperature, they are sealed and packed in bags for storage, thereby completing the preparation of component B.

[0061] Embodiment 3: A Chinese medicine preparation for gynecological inflammation and a preparation method thereof, specifically comprising the following steps:

[0062] Step 1, weighing raw materials: according to the weight ratio of component A, cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue, tortoise glue, ginger preparation, bamboo charcoal powder, Phellodendron extract, lotus root extract, sodium alginate, honey and sesame oil are weighed as raw materials of component A, wherein the weight ratio of component A includes: 15:10:3:15:3:3:10:5:8:7:15:20:3;

[0063] Weigh scallion, Zanthoxylum bungeanum, processed coptis root, sophora flavescens and red safflower according to the weight ratio of component B as raw materials of component B, wherein the weight ratio of component B includes: 5:5:20:3:3;

[0064] Step 2, preparation of component A: put cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue and tortoise glue in a medicine pot, add ten times the amount of water and boil for 3-5 hours;

[0065] When the amount of water is reduced to three times, add the processed ginger and Phellodendron amurense extract, keep the temperature at 45°C for 30 minutes, remove the residue, add bamboo charcoal powder and lotus root extract, and stir at 400r / min for 10 minutes. During the process, keep the temperature of the medicine tank at 30°C.

[0066] Sodium alginate, honey and sesame oil were added, and stirred at 600 r / min for 15 min at a constant temperature of 25°C to obtain an ointment;

[0067] After rolling into pills, the preparation of component A is completed;

[0068] Step 3, preparation of component B: add scallion, pepper, processed coptis root, sophora flavescens and red safflower into a medicine pot, add five times the amount of water and soak for 30 minutes, bring to a boil over high heat, then simmer for 15 minutes over low heat, pour out the liquid medicine to obtain a second lotion;

[0069] Add three times the amount of water again, bring to a boil over high heat, then simmer for 15 minutes over low heat, pour out the liquid, and obtain the first lotion;

[0070] After the first lotion and the second lotion are cooled to room temperature, they are sealed and packed in bags for storage, thereby completing the preparation of component B.

[0071] The method of using the Chinese medicine preparation obtained according to the above-mentioned Example 1, Example 2 and Example 3 includes: adding the first lotion to warm water for a sitz bath for 3-5 minutes, after the affected area is dried, placing the pills prepared from component A into the vagina 5-10 cm deep for 6-12 hours, taking out the pills, and adding the second lotion to warm water for a sitz bath for 5-8 minutes.

[0072] There are differences in the efficacy of the Chinese medicine preparations obtained according to the above-mentioned Example 1, Example 2 and Example 3, as shown in the following table:

[0073] Abnormal vaginal discharge Odor Itching Duration of medication / day Embodiment 1 yes none none 3-5 Embodiment 2 yes slight slight 5-7 Embodiment 3 yes strong strong 10-18

[0074] Efficacy Example

[0075] The Chinese medicinal preparation for gynecological inflammation of the present invention was used to treat gynecological diseases. 150 clinical patients with gynecological diseases were treated. Among them, patients with abnormal leucorrhea could observe a significant reduction in leucorrhea in 3-5 days; moderate patients with abnormal leucorrhea accompanied by slight odor and itching could eliminate the odor and itching in 5-7 days; severe patients with abnormal leucorrhea accompanied by pungent odor and strong itching could fully recover in 10-18 days; and in subsequent follow-up examinations at one week, one month and three months, no odor or itching occurred.

[0076] Ms. Gao, 26 years old, had abnormal leucorrhea. After using the first lotion, pills and second lotion prepared in Example 3 of the present invention on the affected area, she found that the leucorrhea was significantly reduced in three days and returned to normal on the fourth day.

[0077] Ms. Tao, 35 years old, had abnormal leucorrhea with a slight odor. After using the first lotion, pills and second lotion prepared in Example 2 of the present invention to treat the affected area, she found that the leucorrhea was significantly reduced and the odor was significantly eliminated in three days. She continued to use the medicine until the sixth day, and the odor was completely eliminated and she returned to normal.

[0078] Ms. Lu, 42 years old, had abnormal leucorrhea, accompanied by a strong pungent odor and intense itching, and the affected area was loose, which brought great trouble to her life. After using the first lotion, pills and second lotion prepared in Example 1 of the present invention on the affected area, the itching was relieved after three days, and the odor was significantly reduced after seven days. She continued to use the medicine until the 17th day, and her normal state was restored, and the looseness of the affected area was improved.

[0079] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine preparation for gynecological inflammation, characterized in that: include: Component A, wherein the raw materials of component A include, by weight: 15-32 parts of cockscomb, 10-25 parts of motherwort, 3-5 parts of Scrophularia, 15-25 parts of Rehmannia root, 3-8 parts of deer glue, 3-8 parts of tortoise glue, 10-18 parts of processed ginger, 5-12 parts of bamboo charcoal powder, 8-18 parts of Phellodendron chinense extract, 7-16 parts of lotus root extract, 15-25 parts of sodium alginate, 20-35 parts of honey and 3-5 parts of sesame oil; Component B, the raw materials of component B include 5-15 parts of green onion, 5-10 parts of prickly ash, 20-50 parts of processed coptis root, 3-10 parts of sophora flavescens and 3-5 parts of red safflower by weight.

2. The Chinese medicine preparation for gynecological inflammation according to claim 1, characterized in that: include: Component A, wherein the raw materials of component A include, by weight: 32 parts of cockscomb, 25 parts of motherwort, 5 parts of Scrophularia, 25 parts of Rehmannia root, 8 parts of deer glue, 8 parts of tortoise glue, 18 parts of ginger preparation, 12 parts of bamboo charcoal powder, 18 parts of Phellodendron chinense extract, 16 parts of lotus root extract, 25 parts of sodium alginate, 35 parts of honey and 5 parts of sesame oil; Component B, the raw materials of component B include 15 parts of scallion, 10 parts of prickly ash, 50 parts of processed coptis root, 10 parts of sophora flavescens and 5 parts of red sedge by weight.

3. The Chinese medicine preparation for gynecological inflammation according to claim 1, characterized in that: include: Component A, wherein the raw materials of component A include, by weight: 26 parts of cockscomb, 18 parts of motherwort, 4 parts of Scrophularia, 20 parts of Rehmannia root, 6 parts of deer glue, 6 parts of tortoise glue, 14 parts of processed ginger, 9 parts of bamboo charcoal powder, 12 parts of Phellodendron chinense extract, 13 parts of lotus root extract, 20 parts of sodium alginate, 15 parts of honey and 4 parts of sesame oil; Component B, the raw materials of component B include 10 parts of green onion, 9 parts of prickly ash, 35 parts of processed coptis root, 8 parts of sophora flavescens and 4 parts of red safflower by weight.

4. The Chinese medicine preparation for gynecological inflammation according to claim 1, characterized in that: include: Component A, wherein the raw materials of component A include, by weight: 15 parts of cockscomb, 10 parts of motherwort, 3 parts of Scrophularia, 15 parts of Rehmannia root, 3 parts of deer glue, 3 parts of tortoise glue, 10 parts of processed ginger, 5 parts of bamboo charcoal powder, 8 parts of Phellodendron chinense extract, 7 parts of lotus root extract, 15 parts of sodium alginate, 20 parts of honey and 3 parts of sesame oil; Component B, the raw materials of component B include 5 parts of scallion, 5 parts of prickly ash, 20 parts of processed coptis root, 3 parts of sophora flavescens and 3 parts of red safflower by weight.

5. A Chinese medicine preparation for gynecological inflammation according to any one of claims 1 to 4, characterized in that: The ginger processed product comprises peeled ginger paste and ginger juice, wherein the peeled ginger paste and ginger juice are in a weight ratio of 3:5; The peeled ginger paste is prepared by peeling the ginger, crushing and squeezing it, and soaking the filtered solid ginger in water for 15-30 minutes, then taking it out and drying it to obtain the peeled ginger paste; The ginger juice is the juice squeezed from fresh young ginger after peeling.

6. A Chinese medicine preparation for gynecological inflammation according to any one of claims 1 to 4, characterized in that: The lotus root extract comprises lotus root silk, lotus root powder and lotus leaf, wherein the weight ratio of lotus root silk, lotus root powder and lotus leaf is 1:25:65; The lotus leaf is naturally dried and ground into powder, and then sieved through a 200-mesh sieve; The lotus root silk is short silk of 1-2 mm.

7. A Chinese medicine preparation for gynecological inflammation according to any one of claims 1 to 4, characterized in that: The processed Rhizoma Coptidis comprises Rhizoma Coptidis and yellow wine, wherein the weight ratio of Rhizoma Coptidis to yellow wine is 1:8; The coptis root is soaked in rice wine for at least 24 hours.

8. A method for preparing a Chinese medicine preparation for gynecological inflammation, characterized in that: The specific steps include: Step 1, weighing raw materials: according to the weight ratio of component A, weigh cockscomb, motherwort, Scrophularia, raw rehmannia, deer glue, tortoise glue, ginger processing, bamboo charcoal powder, phellodendron extract, lotus root extract, sodium alginate, honey and sesame oil as the raw materials of component A; Weigh scallion, Zanthoxylum bungeanum, processed Coptis chinensis, Sophora flavescens and Caulis Scutellariae in accordance with the weight ratio of component B as raw materials of component B; Step 2, preparation of component A: put cockscomb, motherwort, Scrophularia, Rehmannia root, deer glue and tortoise glue in a medicine pot, add ten times the amount of water and boil for 3-5 hours; When the amount of water is reduced to three times, add the processed ginger and Phellodendron amurense extract, keep the temperature at 45°C for 30 minutes, remove the residue, add bamboo charcoal powder and lotus root extract, and stir at 400r / min for 10-15 minutes. During the process, keep the temperature of the medicine tank at 30°C. Add sodium alginate, honey and sesame oil, stir at 600 r / min for 15-20 min at a constant temperature of 25°C to obtain an ointment; After rolling into pills, the preparation of component A is completed; Step 3, preparation of component B: add scallion, pepper, processed coptis root, sophora flavescens and red safflower into a medicine pot, add five times the amount of water and soak for 30 minutes, bring to a boil over high heat, then simmer for 15-20 minutes over low heat, pour out the liquid medicine to obtain the second lotion; Add three times the amount of water again, bring to a boil over high heat, then simmer for 15-20 minutes over low heat, pour out the liquid, and obtain the first lotion; After the first lotion and the second lotion are cooled to room temperature, they are sealed and packed in bags for storage, thereby completing the preparation of component B.

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