Detection sensor and detection system for pressure in living body

Abstract

The invention provides an in-vivo pressure detection sensor and detection system, and the sensor comprises an air bag which is used for being implanted into a to-be-detected part; the first air pressure sensor is located in the environment communicated with air in the air bag and used for measuring the air pressure value in the air bag, the air bag and the first air pressure sensor are combined to monitor the pressure in the organism, the size of the detection sensor is effectively reduced, the air bag is used for directly measuring the intracranial pressure, and the accurate intracranial pressure value is obtained. The brain tissue is prevented from being exposed to the injury risk; the first wireless power supply and communication module is used for wirelessly supplying power to internal components of the detection sensor and directly sending measured parameters to an external receiver, so that the structure of the detection sensor has high integration, a battery does not need to be arranged, the volume size of the detection sensor is further reduced, and the cost is reduced. The use experience of an implanter is improved, the processing performance and the communication performance of the detection sensor can be guaranteed, and the operation convenience of the detection sensor is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to an in vivo pressure detection sensor and a detection system. Background Art

[0002] Intracranial pressure (ICP) is the pressure exerted by the components within the brain ventricles. Increased intracranial pressure is a common manifestation of intracranial disease or secondary intracranial disease. Dynamic and continuous monitoring of intracranial pressure plays an important role in determining intracranial disease and injury, guiding medication, and estimating prognosis.

[0003] Invasive intracranial pressure measurement through intracranial catheters and bedside sensing devices is the most commonly used method and is considered the gold standard. However, the above invasive intracranial pressure measurement has a significant risk of infectious complications and is inconvenient for patients. Commercial wireless intracranial pressure monitoring systems are a better choice to solve the above problems compared to intracranial catheters, but these devices have the problem of large size, for example, some devices have an outer diameter of up to 23.8mm×7.7mm.

[0004] Existing intracranial pressure monitoring sensors have the problem of being too large, which reduces the user experience of the intracranial pressure monitoring sensors. Summary of the invention

[0005] The purpose of the present invention is to provide a biological body pressure detection sensor and detection system, including: an airbag, which is used to be implanted in a part to be tested; a first air pressure sensor, which is in an environment connected to the gas in the airbag, and is used to measure the air pressure value in the airbag. The liquid pressure value of the part to be tested can be obtained by combining the airbag with the first air pressure sensor, which provides a data basis for the subsequent determination of the pressure value of the part to be tested. The airbag structure and the air pressure sensor are used in combination to effectively reduce the volume size of the detection sensor. At the same time, the airbag structure can avoid the risk of damage caused by direct contact between the pressure sensor or other electronic components and the tissue in the body; the above-mentioned detection sensor can also include a first wireless power supply and communication module, which realizes wireless power supply to the internal components of the detection sensor and communication with external devices, so that the structure of the detection sensor has a high degree of integration, and does not need to set a battery, further reducing the volume size of the detection sensor, improving the user experience of the implanter, and ensuring the processing performance and communication performance of the detection sensor. At the same time, it solves the disadvantage that the wound needs to be continuously exposed when the wired detection sensor is used. The implanter can suture the wound after implanting the detection sensor, reducing the risk of clinical infection and the postoperative activity restriction of the implanter. The present invention improves the operational convenience of the detection sensor and expands the application scenarios, and can provide real-time and reliable data basis for judging diseases and injuries.

[0006] The present invention is achieved through the following technical solutions:

[0007] A biological body pressure detection sensor, comprising:

[0008] An air bag is used to be implanted in the part to be tested;

[0009] The first air pressure sensor is located in an environment connected to the gas in the airbag and is used to measure the air pressure value in the airbag.

[0010] In one embodiment, the airbag has a first open end;

[0011] The biological body pressure detection sensor also includes:

[0012] a first housing, wherein the first air pressure sensor is disposed inside the first housing;

[0013] The first shell has an open end, and the open end is connected to the first open end of the airbag, so that the interior of the first shell is in gas communication with the airbag.

[0014] In one embodiment, the first shell has an open end, and the open end is connected to the first open end of the airbag, so that the interior of the first shell is in gas communication with the airbag, specifically:

[0015] A conduit is arranged on the surface of the first shell, one opening end of the conduit is communicated with the inner space of the first shell, and the other opening end of the conduit is communicated with the first opening end of the airbag.

[0016] In one embodiment, the first shell and the conduit are integrally formed.

[0017] In one embodiment, a support member, wherein the first housing is fixed to the support member;

[0018] The support component is also provided with a first microprocessor and a first wireless power supply and communication module;

[0019] The first wireless power supply and communication module is used to supply power to the first microprocessor and the first air pressure sensor, and to communicate with an external receiver;

[0020] The first microprocessor is used to control the working state of the first air pressure sensor, obtain the air pressure value measured by the first air pressure sensor, and perform a first preset process on the air pressure value measured by the first air pressure sensor.

[0021] In one embodiment, the first preset process includes:

[0022] sending the air pressure value measured by the first air pressure sensor to an external receiver through the first wireless power supply and communication module;

[0023] or,

[0024] The pressure value of the part to be measured is determined according to the air pressure value measured by the first air pressure sensor, and the pressure value of the part to be measured is sent to an external receiver through the first wireless power supply and communication module.

[0025] In one embodiment, the first wireless power supply and communication module includes: a first NFC chip and a receiving coil;

[0026] The first NFC chip is used to receive energy transmitted by an external receiver through the receiving coil and convert it into a preset voltage, thereby powering the first microprocessor and the first air pressure sensor; and to communicate with external devices.

[0027] In one embodiment, the supporting component comprises an integrated circuit board, and the receiving coil is disposed on the integrated circuit board.

[0028] In one embodiment, a support rod, one end of which passes through the first shell and is connected to the support component, and the other end of which extends into the airbag.

[0029] In one embodiment, when the supporting component is an integrated circuit board:

[0030] The airbag also has a second open end, and the second open end is provided with a heat-conducting plug;

[0031] The other end of the support rod extends through the airbag and is connected to the heat-conducting plug;

[0032] A temperature sensor is arranged in the heat-conducting plug.

[0033] In one embodiment, the first microprocessor is further used to obtain the temperature value of the measured part monitored by the temperature sensor, and send the temperature value of the measured part to an external receiver through the first wireless power supply and communication module.

[0034] In one embodiment, the in vivo pressure detection sensor further comprises:

[0035] The second shell is used to cover and protect the supporting component and the components arranged on the supporting component.

[0036] In one embodiment, the present application further provides a biological in vivo pressure detection system, comprising any biological in vivo pressure detection sensor as described above, and a receiver.

[0037] The receiver includes a processor, a second wireless power supply and communication module;

[0038] The second wireless power supply and communication module is used to cooperate with the first wireless power supply and communication module of the in vivo pressure detection sensor to realize power supply to the internal components of the in vivo pressure detection sensor; and communicate with the first wireless power supply and communication module of the in vivo pressure detection sensor to obtain the parameter value measured by the in vivo pressure detection sensor;

[0039] The processor is used to perform a second preset process on the parameter value.

[0040] In one embodiment, the parameter value includes the air pressure value measured by the first air pressure sensor, or the pressure value of the part to be measured;

[0041] The second preset process includes:

[0042] When the parameter value includes the air pressure value measured by the first air pressure sensor, the pressure value of the part to be measured is determined according to the air pressure value measured by the first air pressure sensor.

[0043] In one embodiment, the second wireless power supply and communication module includes a transmitting coil and a second NFC chip.

[0044] In one embodiment, the receiver further comprises a main body bearing portion and a transmitting coil bearing portion;

[0045] Wherein, the processor and the second NFC chip are arranged on the main body bearing part;

[0046] The transmitting coil is arranged on the transmitting coil bearing portion;

[0047] The main body bearing part and the transmitting coil bearing part are arranged separately;

[0048] The components on the main body bearing part are electrically connected and / or signal-connected to the transmitting coil on the transmitting coil bearing part through the connecting component.

[0049] In one embodiment, the connecting component is electrically and / or signal-connected to the components on the main body carrying portion in a detachable manner;

[0050] and / or

[0051] The connecting component is detachably connected to the transmitting coil on the transmitting coil bearing portion for electrical and / or signal connection.

[0052] In one embodiment, the receiver further comprises a second air pressure sensor for measuring the atmospheric pressure;

[0053] When the parameter value includes the air pressure value measured by the first air pressure sensor, determining the pressure value of the part to be measured according to the air pressure value measured by the first air pressure sensor comprises:

[0054] When the parameter value includes the air pressure value measured by the first air pressure sensor, the pressure value of the to-be-measured part is determined according to the atmospheric pressure and the air pressure value measured by the first air pressure sensor.

[0055] In one embodiment, the receiver further includes at least one of a wireless communication module and a display module; wherein,

[0056] The wireless communication module is connected to the processor signal to realize two-way communication between the receiver and the external terminal;

[0057] The display module is used to perform display operations according to the control of the processor.

[0058] Compared with the prior art, the present invention has the following beneficial effects:

[0059] The use of an airbag structure and an air pressure sensor effectively reduces the size of the detection sensor. At the same time, the use of an airbag structure can avoid the risk of damage caused by direct contact between the pressure sensor or other electronic components and the tissue in the body. The above-mentioned detection sensor may also include a first wireless power supply and communication module, which realizes wireless power supply to the internal components of the detection sensor and communication with external devices, so that the structure of the detection sensor has a high degree of integration, and does not require the provision of batteries, further reducing the size of the detection sensor, improving the user experience of the implanter, and ensuring the processing performance and communication performance of the detection sensor. At the same time, it solves the disadvantage of the wired detection sensor that the wound needs to be continuously exposed when used. The implanter can suture the wound after the detection sensor is implanted, reducing the risk of clinical infection and the postoperative activity restrictions of the implanter. The present invention improves the ease of operation of the detection sensor and expands the application scenarios, and can provide real-time and reliable data basis for judging diseases and injuries. BRIEF DESCRIPTION OF THE DRAWINGS

[0060] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the prior art descriptions. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:

[0061] Figure 1 This is a schematic diagram of the first structure of a biological in vivo pressure detection sensor provided by the present invention.

[0062] Figure 2 This is a second structural schematic diagram of an in vivo pressure detection sensor provided by the present invention.

[0063] Figure 3 This is a third structural schematic diagram of an in vivo pressure detection sensor provided by the present invention.

[0064] Figure 4 This is a fourth structural schematic diagram of an in vivo pressure detection sensor provided by the present invention.

[0065] Figure 5 A schematic diagram of the connection of internal components of a biological in vivo pressure detection sensor provided by the present invention.

[0066] Figure 6 This is a schematic diagram of the principle of a biological body pressure detection sensor provided by the present invention.

[0067] Figure 7 The present invention provides an overall schematic diagram of a biological in vivo pressure detection sensing system.

[0068] Figure 8 A data diagram of a wireless energy transmission test result between a transmitting coil and a receiving coil in a biological body pressure detection sensor system provided by the present invention;

[0069] Fig. 9 A data diagram showing the test results of a biological body pressure detection sensor system provided by the present invention used in a water tank experiment scenario;

[0070] Fig.10 This is a data graph of nonlinear error test results of a biological in vivo pressure detection sensor system provided by the present invention.

[0071] Figure numerals: 1. airbag; 2. first air pressure sensor; 3. first shell; 4. plug; 5. support rod; 6. support component; 7. first microprocessor; 8. first wireless power supply and communication module; 9. second shell; 10. receiving coil; 11. first NFC chip. DETAILED DESCRIPTION

[0072] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. It is to be understood that the specific embodiments described herein are only used to explain the present application, rather than to limit the present application. It should also be noted that, for ease of description, only some structures related to the present application are shown in the accompanying drawings, rather than all structures. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of this application.

[0073] The terms "including" and "having" and any variations thereof in this application are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device comprising a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units not listed, or may optionally include other steps or units inherent to these processes, methods, products or devices.

[0074] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0075] like Figure 1 As shown, the first structure of the in vivo pressure detection sensor provided by the embodiment of the present application is shown. The in vivo pressure detection sensor comprises an airbag 1 and a pressure sensor. The airbag 1 is used to be implanted in the part to be tested, so that the airbag 1 is in direct contact with the inside of the part to be tested; the part to be tested may be, but is not limited to, a cerebral ventricle, a bladder, etc. The first air pressure sensor 2 is in an environment connected to the gas in the airbag 1, and is used to measure the air pressure value in the airbag 1.

[0076] The airbag 1 itself is flexible and deformable, and can be made of flexible materials such as rubber, so that when the airbag 1 is implanted in a part to be tested, such as a cerebral ventricle or a bladder, the airbag 1 can be deformed under the liquid pressure of the liquid substance in the part to be tested, thereby changing the pressure of the gas environment inside the airbag 1. The shape of the airbag can be set as needed.

[0077] When the airbag 1 is in direct contact with the part to be measured (for example, it is in contact with the cerebrospinal fluid in the ventricles, or it is in contact with the liquid in the bladder), the liquid substance in the part to be measured will compress the outer wall of the airbag 1 due to its own liquid pressure, causing the airbag 1 to deform. At this time, the internal air pressure of the airbag 1 is equal to the liquid pressure of the liquid substance in the part to be measured. Because the first air pressure sensor 2 is in a state of being connected to the gas in the airbag 1, the air pressure value measured by the first air pressure sensor 2 is the air pressure value inside the airbag 1, that is, the liquid pressure value of the liquid substance in the part to be measured, which provides a direct data basis for the subsequent determination of the pressure value of the part to be measured.

[0078] It can be seen through Figure 1The airbag 1 shown is combined with the first air pressure sensor 2 to form a detection sensor of a corresponding structure, which realizes the measurement of the liquid pressure value of the liquid substance in the measured part while using a smaller number of components, and further realizes the measurement of the pressure value of the measured parts such as the ventricles and bladder, effectively reducing the volume size of the detection sensor, realizing the miniaturization of the detection sensor, and avoiding direct contact between the sensor or other electronic components and human tissue to avoid potential infection risks.

[0079] In order to improve the detection performance of the detection sensor, further improvements are made on the basis of the detection sensor of the first structure mentioned above, as follows:

[0080] In an implementation, if Figure 2 As shown, the airbag 1 has a first opening end. At this time, the in vivo pressure detection sensor also includes:

[0081] A first housing 3, wherein the first air pressure sensor 2 is arranged inside the first housing 3;

[0082] The first shell 3 has an open end 20 , which is connected to the first open end of the airbag 1 , so that the interior of the first shell 3 is in gas communication with the airbag 1 .

[0083] Among them, the first shell 3 completely wraps the first air pressure sensor 3, and a certain size of space is left between the first shell 3 and the outer surface of the first air pressure sensor 2 (so that the first air pressure sensor 2 is in a gas environment connected to the airbag 1), and only one open end 20 is left on the first shell 3, and the open end 20 is connected to the first open end of the airbag 1, so that the inside of the first shell 3 forms a gas connection state with the airbag 1, so that the air pressure value measured by the first air pressure sensor 2 is equal to the air pressure value inside the airbag 1. Preferably, the effective detection surface of the first air pressure sensor 2 is preferably arranged toward the gas containing space formed between the first shell, so that the effective detection surface of the first air pressure sensor can be fully in contact with the gas environment of the airbag 1, thereby improving the accuracy of air pressure detection.

[0084] Specifically, Figure 3 As shown above Figure 2 The phrase “the first shell 3 has an open end 20, which is connected to the first open end of the airbag 1, so that the interior of the first shell 3 is in gas communication with the airbag 1” can be specifically implemented as follows: Figure 3In the form shown, a conduit 30 is provided on the surface of the first shell 3, one opening end of the conduit 30 is connected to the space inside the first shell 3, and the other opening end is connected to the first opening end of the airbag 1. Preferably, the first shell 3 and the conduit 30 are integrally formed, so that the airtightness of the connection between the first shell 3 and the conduit can be ensured. The conduit can be a hollow tubular structure, and the conduit serves as a connecting medium to achieve the connection between the internal space of the first shell 3 and the internal space of the airbag 1.

[0085] The first open end of the airbag 1 is sealed and connected to the other open end of the catheter, which can ensure the airtightness of the connection between the airbag 1 and the catheter, avoid air leakage at the connection between the airbag 1 and the catheter, and disturb the air pressure in the internal space of the detection sensor, thereby affecting the detection accuracy of intracranial pressure.

[0086] In another embodiment, Figure 4 As shown, the in vivo pressure detection sensor may also include:

[0087] A support member 6, on which the first housing 3 is fixed, so as to improve the mechanical stability of the first housing 3;

[0088] The support component 6 is also provided with a first microprocessor 7 and a first wireless power supply and communication module 8;

[0089] The first wireless power supply and communication module 8 is connected to the first microprocessor 7 and the first air pressure sensor 2, and can supply power to the first microprocessor 7 and the first air pressure sensor 2, and communicate with the external receiver 12, that is, the first wireless power supply and communication module 8 can realize the power supply to the internal components of the detection sensor and the communication function with the external device in a wireless manner;

[0090] The first microprocessor 7 is used to control the working states of the first air pressure sensor 2, such as the measurement frequency and the switch action, and obtain the air pressure value measured by the first air pressure sensor 2, and perform a first preset processing on the air pressure value measured by the first air pressure sensor 2.

[0091] In one embodiment, the first preset processing can be implemented as follows: the air pressure value measured by the first air pressure sensor 2 is sent to an external receiver through the first wireless power supply and communication module 8; and the external receiver determines the pressure value of the measured part according to the air pressure value measured by the first air pressure sensor 2.

[0092] Alternatively, the first preset processing can also be implemented as follows: according to the air pressure value measured by the first air pressure sensor 2, determine the pressure value of the part to be measured; and then send the pressure value of the part to be measured to an external receiver through the first wireless power supply and communication module 8. Among them, "determine the pressure value of the part to be measured according to the air pressure value measured by the first air pressure sensor 2" here can be specifically implemented as follows: obtain the atmospheric pressure of the current environment; subtract the air pressure value measured by the first air pressure sensor 2 from the atmospheric pressure, and the difference is the pressure value of the part to be measured. Among them, obtaining the atmospheric pressure of the current environment can be that the detection sensor obtains the atmospheric pressure of the current environment from other external devices through the first wireless power supply and communication module. The other devices here can be an external receiver or any other external device that can measure the atmospheric pressure, which is not limited here.

[0093] In one embodiment, the first wireless power supply and communication module may include a first NFC chip and a receiving coil. The arrangement and position of these two components in the detection sensor can be adjusted as needed. The first NFC chip is used to receive energy transmitted by an external receiver through the receiving coil and convert it into a preset voltage, thereby powering the first microprocessor and the first air pressure sensor; and communicating with external devices.

[0094] In a specific embodiment, Figure 5 As shown, the support component 6 can also be specifically implemented as an integrated circuit board 40, and a receiving coil 10 is provided on the integrated circuit board 40; the first microprocessor 7 is respectively connected to the first air pressure sensor 2 and the first NFC chip 11 for signal connection; the receiving coil 10 is electrically connected to the first NFC chip 11, and transfers the energy received from the external receiver to the first NFC chip 11; and the first NFC chip 11 is respectively electrically connected to the first microprocessor 7 and the first air pressure sensor 2, so that the first NFC chip 11 converts the received energy into a preset voltage, thereby providing stable power supply to the first microprocessor 7 and the first air pressure sensor 2.

[0095] The structure corresponding to this embodiment avoids the need to provide a battery in the detection sensor, and the wireless power supply and wireless communication modules can be reused, so the number of components of the entire detection sensor is small, thereby further reducing the size of the detection sensor.

[0096] In another embodiment, Figure 4As shown, since the airbag 1 is made of a flexible material, in order to make the airbag 1 have sufficient mechanical strength to be implanted in the part to be tested, the detection sensor may further include a support rod 5, one end of which passes through the first shell 3 and is connected to the support component 6, and the other end of which extends into the airbag 1. The material of the support rod 5 may be a material with sufficient hardness and toughness, such as titanium wire, and the support rod 5 may be, but is not limited to, a slender rod-shaped structure, so that a sufficiently large support effect can be provided for the airbag while minimizing the space volume occupied by the support rod 5 inside the detection sensor.

[0097] Furthermore, when the supporting component is implemented as the above-mentioned integrated circuit board, the airbag 1 may also have a second open end, and the second open end is provided with a thermal plug 4 (the first shell 3, the airbag 1 and the thermal plug 4 form a closed gas environment space; the material of the thermal plug can be metal or any material with high thermal conductivity, which is not limited in this application); at this time, the other end of the support rod extends through the airbag and is connected to the thermal plug, and a temperature sensor may also be provided in the thermal plug. When the detection sensor is implanted in the part to be measured, the thermal plug 4 and the temperature sensor realize the measurement of the temperature value of the part to be measured.

[0098] Furthermore, the first microprocessor can obtain the temperature value of the measured part measured by the temperature sensor, and transmit the temperature value to the first wireless power supply and communication module, thereby sending the measured temperature value of the measured part to an external receiver, thereby realizing synchronous measurement of the pressure value and temperature value of the measured part.

[0099] Preferably, in one embodiment, the support rod 5 can be implemented as a conductive support rod that can conduct electricity (in this case, the material of the support rod can be a conductive material, or a conductive structure can be set inside the support rod made of other materials), one end of the conductive support rod is electrically connected to the circuit on the integrated circuit board, and the other end extends through the airbag and is connected to the thermal plug; the temperature sensor is electrically connected to the conductive support rod, so that the temperature sensor is connected to the first microprocessor on the integrated circuit board; this structure makes the functional components of the detection sensor further highly integrated and reduces the volume size of the detection sensor.

[0100] In addition, the in vivo pressure detection sensor also includes a second shell 9, which is used to cover and protect the support component 6 and the components arranged on the support component 6, so as to prevent the detection sensor from being damaged by the corresponding components due to collision during use, and to prevent the components from directly contacting the in vivo tissue to avoid the risk of infection.

[0101] The working principle of the in vivo pressure detection sensor in this application is explained below:

[0102] like Figure 6As shown, the measuring principle of the in vivo pressure detection sensor of the present application is as follows: when the airbag 1 of the detection sensor is implanted into the part to be measured, the outer wall of the airbag 1 contacts the liquid substance such as cerebrospinal fluid in the part to be measured, and the air pressure P inside the airbag 1 is INT The absolute pressure P of the liquid substance at the measured part CSF Since the first shell 3 and the airbag 1 form a gas communication environment, and the heat conductive plug blocks the other end of the airbag 1, thereby forming a closed gas space, the absolute pressure P measured by the first air pressure sensor 2 inside the first shell 3 is sens Equal to the air pressure P inside the airbag 1 INT , that is, the absolute pressure P measured by the first air pressure sensor 2 sens Equal to the absolute pressure P of the part to be measured CSF .

[0103] like Figure 7 As shown, the present application also provides an in vivo pressure detection system, including the above-mentioned in vivo pressure detection sensor, and a receiver 50; the receiver 50 includes a processor, a second wireless power supply and communication module; the second wireless power supply and communication module is used to cooperate with the first wireless power supply and communication module of the in vivo pressure detection sensor to realize power supply to internal components of the in vivo pressure detection sensor; and communicate with the first wireless power supply and communication module of the in vivo pressure detection sensor to obtain parameter values ​​measured by the in vivo pressure detection sensor; the processor is used to perform a second preset processing on the parameter value.

[0104] In one embodiment, the second wireless power supply and communication module may include a transmitting coil and a second NFC chip; correspondingly, the first wireless power supply and communication module may be implemented as a receiving coil and a first NFC chip. Of course, the receiver is provided with a power supply module such as a battery for powering itself, and the processor controls the power supply module to provide energy to the transmitting coil, and the transmitting coil and the receiving coil transmit energy by electromagnetic induction, and then the first NFC chip is used to realize wireless power supply of the components in the detection sensor.

[0105] In one embodiment, the parameter value measured by the in-vivo pressure detection sensor acquired by the receiver may include the air pressure value measured by the first air pressure sensor or the pressure value of the part to be measured.

[0106] Among them, when the parameter value includes the air pressure value measured by the first air pressure sensor, the above-mentioned second preset processing can be specifically implemented as: obtaining the atmospheric pressure of the current environment; subtracting the air pressure value measured by the first air pressure sensor from the atmospheric pressure of the current environment, and the difference is the pressure value of the measured part.

[0107] Preferably, the above-mentioned acquisition of the atmospheric pressure of the current environment can be implemented as follows: the atmospheric pressure of the current environment is acquired from other external devices through the second wireless power supply and communication module. Alternatively, the above-mentioned receiver measures the atmospheric pressure of the current environment by itself, and in this case, the receiver may also include a second air pressure sensor for measuring the atmospheric pressure.

[0108] In one embodiment, in order to facilitate wireless power supply to the detection sensor implanted in the body, such as Figure 7 As shown, the receiver 50 also includes a main body bearing part 12 (for example, a shell) and a transmitting coil bearing part 13 (for example, a circuit board with an integrated transmitting coil); wherein the processor and the second NFC chip are arranged on the main body bearing part, the transmitting coil is arranged on the transmitting coil bearing part, and the main body bearing part and the transmitting coil bearing part are arranged separately; the components on the main body bearing part are electrically connected and / or signal-connected with the transmitting coil on the transmitting coil bearing part through the connecting part. Wherein, the connecting part can be electrically connected and / or signal-connected with the components on the main body bearing part in a detachable manner; it can also be electrically connected and / or signal-connected with the transmitting coil on the transmitting coil bearing part in a detachable manner, so as to be more convenient to use and store. The connecting part can be a detachable connecting part, for example, a transmission line with pluggable connectors or interfaces at both ends, and accordingly, one end connector (or interface) on the transmission line connected to the components on the main body bearing part of the receiver is adapted to the interface (or connector) arranged on the main body bearing part; the other end connector (or interface) on the transmission line connected to the transmitting coil on the transmitting coil bearing part is adapted to the interface (or connector) arranged on the transmitting coil bearing part. In addition, the connecting component may be connected to the transmitting coil on the transmitting coil bearing part in a fixed connection manner, and a pluggable interface (or connector) is provided at one end connected to the components on the main body bearing part of the receiver, and correspondingly, a correspondingly adapted pluggable connector (or interface) is provided on the main body bearing part of the receiver. The length of the transmission line can be set as needed.

[0109] The following examples illustrate the use of the above receiver and detection sensor: Figure 7 As shown, the upper part of the in-vivo pressure detection sensor (i.e., the supporting part provided with the first microprocessor, the first wireless power supply and the communication module and other components) is placed between the outer side of the skull and the subcutaneous part of the organism, and the lower part (the airbag part) is inserted into the brain substance or ventricle of the organism through the skull opening (the airbag of appropriate length is selected as needed). After implantation, the scalp on the skull is sutured, and the transmitting coil bearing part of the receiver is fixed to the outer side of the scalp layer by a bandage or other means, and the transmitting coil of the receiver is placed in a concentric position with the receiving coil of the detection sensor, and the total percutaneous spacing does not exceed the specified distance to ensure the energy transmission efficiency between the transmitting coil and the receiving coil.

[0110] In one embodiment, the receiver also includes at least one of a wireless communication module and a display module; wherein the wireless communication module is connected to the processor signal to realize two-way communication between the receiver and an external terminal; the display module is used to perform display operations according to the control of the processor, thereby realizing a visual display of the pressure value of the measured part.

[0111] like Figure 8 The figure shows the test results of wireless energy transmission between the transmitting coil and the receiving coil in the in vivo pressure detection sensor system of the present invention. In the wireless energy transmission test, the receiving coil was implanted between 3mm pig skin and 5mm pork tenderloin to simulate the human body implantation environment, and the wireless energy transmission efficiency (PTE) between the transmitting coil and the receiving coil was tested. Figure 8 It can be seen that the maximum working distance between the transmitting coil and the receiving coil reaches 17 mm, that is, within a distance range less than or equal to 17 mm, stable and efficient wireless energy transmission can be achieved between the transmitting coil and the receiving coil.

[0112] like Fig. 9 Shown is a data graph of the test results of the in vivo pressure detection sensor system of the present invention used in a water tank experimental scenario. In the water tank experimental scenario, a water tank experimental device is built to provide a controllable in vitro experimental environment for the in vivo pressure detection sensor system, thereby verifying the feasibility of using the in vivo pressure detection sensor system for liquid pressure measurement. Specifically, the in vivo pressure detection sensor of the in vivo pressure detection sensor system is placed in a water tank, and the underwater depth of the in vivo pressure detection sensor inside the water tank is adjusted, and a ruler or other tools are used to measure the underwater depth of the in vivo pressure detection sensor. According to the measured underwater depth, the water pressure intensity at the location of the in vivo pressure detection sensor is calculated, and the water pressure intensity measured by the in vivo pressure detection sensor system itself is obtained. The test results are shown in the figure below. Fig. 9 As shown, within the range of 0 to 18 mmHg, the difference between the measured water pressure intensity and the calculated water pressure intensity is less than ±0.1 mmHg.

[0113] like Fig.10 The figure shows the full-scale nonlinear error test result data of the in vivo pressure detection sensor system of the present invention. Fig.10 It can be seen that the test range is -20 to 150 mmHg, and in the entire test range, the measurement nonlinear error is less than ±0.3 mmHg.

[0114] In general, the in vivo pressure detection sensor and detection system include: an airbag, which is used to be implanted in the part to be tested; a first air pressure sensor, which is in an environment connected to the gas in the airbag and is used to measure the air pressure value in the airbag. The liquid pressure value of the part to be tested can be obtained by combining the airbag and the first air pressure sensor, which provides a data basis for the subsequent determination of the pressure value of the part to be tested. The airbag structure and the air pressure sensor are used in combination to effectively reduce the volume size of the detection sensor. At the same time, the airbag structure can avoid the risk of damage caused by direct contact between the pressure sensor or other electronic components and the tissue in the body; the above-mentioned detection sensor may also include a first wireless power supply and communication module, which realizes wireless power supply to the internal components of the detection sensor and communication with external equipment, so that the structure of the detection sensor has a high degree of integration, and no battery is required, which further reduces the volume size of the detection sensor, improves the user experience of the implanter, and can also ensure the processing performance and communication performance of the detection sensor, improve the ease of operation of the detection sensor, and provide real-time and reliable data basis for judging diseases and injuries.

[0115] The above is only a specific implementation of the present invention, and any other improvements made based on the concept of the present invention are considered to be within the protection scope of the present invention.

Claims

1. A biological body pressure detection sensor, characterized in that: include: An air bag is used to be implanted in the part to be tested; The first air pressure sensor is located in an environment connected to the gas in the airbag and is used to measure the air pressure value in the airbag.

2. The bio-based in vivo pressure detection sensor according to claim 1, characterized in that: The airbag has a first open end; The biological body pressure detection sensor also includes: a first housing, wherein the first air pressure sensor is disposed inside the first housing; The first shell has an open end, and the open end is connected to the first open end of the airbag, so that the interior of the first shell is in gas communication with the airbag.

3. The in vivo pressure detection sensor according to claim 2, wherein: The first shell has an open end, which is connected to the first open end of the airbag, so that the interior of the first shell and the airbag are in a gas communication state. Specifically, a conduit is provided on the surface of the first shell, one open end of the conduit is communicated with the space inside the first shell, and the other open end of the conduit is communicated with the first open end of the airbag.

4. The in vivo pressure detection sensor according to claim 3, wherein: The first shell and the conduit are integrally formed.

5. The in vivo pressure detection sensor according to any one of claims 2 to 4, characterized in that: Also includes: A supporting component, wherein the first shell is fixed on the supporting component; The support component is also provided with a first microprocessor and a first wireless power supply and communication module; The first wireless power supply and communication module is used to supply power to the first microprocessor and the first air pressure sensor, and to communicate with an external receiver; The first microprocessor is used to control the working state of the first air pressure sensor, obtain the air pressure value measured by the first air pressure sensor, and perform a first preset process on the air pressure value measured by the first air pressure sensor.

6. The in vivo pressure detection sensor according to claim 5, characterized in that: The first preset process includes: sending the air pressure value measured by the first air pressure sensor to an external receiver through the first wireless power supply and communication module; or, The pressure value of the part to be measured is determined according to the air pressure value measured by the first air pressure sensor, and the pressure value of the part to be measured is sent to an external receiver through the first wireless power supply and communication module.

7. The in vivo pressure detection sensor according to claim 5, characterized in that: The first wireless power supply and communication module includes: a first NFC chip and a receiving coil; The first NFC chip is used to receive energy transmitted by an external receiver through the receiving coil and convert it into a preset voltage, thereby powering the first microprocessor and the first air pressure sensor; and to communicate with external devices.

8. The in vivo pressure detection sensor according to claim 7, characterized in that: The supporting component includes an integrated circuit board, and the receiving coil is arranged on the integrated circuit board.

9. The in vivo pressure detection sensor according to claim 5, wherein: Also includes: A support rod, one end of which passes through the first shell and is connected to the support component, and the other end of which extends into the airbag.

10. The in vivo pressure detection sensor according to claim 9, wherein: When the supporting component is an integrated circuit board: The airbag also has a second open end, and the second open end is provided with a heat-conducting plug; The other end of the support rod extends through the airbag and is connected to the heat-conducting plug; A temperature sensor is arranged in the heat-conducting plug.

11. The in vivo pressure detection sensor according to claim 10, wherein: The first microprocessor is also used to obtain the temperature value of the measured part monitored by the temperature sensor, and send the temperature value of the measured part to an external receiver through the first wireless power supply and communication module.

12. The in vivo pressure detection sensor according to any one of claims 5 to 11, characterized in that: Also includes: The second shell is used to cover and protect the supporting component and the components arranged on the supporting component.

13. A biological body pressure detection system, comprising the biological body pressure detection sensor according to any one of claims 5 to 11, and a receiver, characterized in that: The receiver includes a processor, a second wireless power supply and communication module; The second wireless power supply and communication module is used to cooperate with the first wireless power supply and communication module of the in vivo pressure detection sensor to realize power supply to the internal components of the in vivo pressure detection sensor; and communicate with the first wireless power supply and communication module of the in vivo pressure detection sensor to obtain the parameter value measured by the in vivo pressure detection sensor; The processor is used to perform a second preset process on the parameter value.

14. The in vivo pressure detection system according to claim 13, wherein: The parameter value includes the air pressure value measured by the first air pressure sensor, or the pressure value of the part to be measured; The second preset process includes: When the parameter value includes the air pressure value measured by the first air pressure sensor, the pressure value of the part to be measured is determined according to the air pressure value measured by the first air pressure sensor.

15. The in vivo pressure detection system according to claim 13, wherein: The second wireless power supply and communication module includes a transmitting coil and a second NFC chip.

16. The in vivo pressure detection system according to claim 15, wherein: The receiver also includes a main body bearing part and a transmitting coil bearing part; Wherein, the processor and the second NFC chip are arranged on the main body bearing part; The transmitting coil is arranged on the transmitting coil bearing portion; The main body bearing part and the transmitting coil bearing part are arranged separately; The components on the main body bearing part are electrically connected and / or signal-connected to the transmitting coil on the transmitting coil bearing part through the connecting component.

17. The in vivo pressure detection system according to claim 16, wherein: The connecting component is electrically and / or signal-connected to the components on the main body bearing part in a detachable manner; and / or The connecting component is detachably connected to the transmitting coil on the transmitting coil bearing portion for electrical and / or signal connection.

18. The in vivo pressure detection system according to claim 14, wherein: The receiver also includes a second air pressure sensor for measuring atmospheric pressure; When the parameter value includes the air pressure value measured by the first air pressure sensor, determining the pressure value of the part to be measured according to the air pressure value measured by the first air pressure sensor comprises: When the parameter value includes the air pressure value measured by the first air pressure sensor, the pressure value of the to-be-measured part is determined according to the atmospheric pressure and the air pressure value measured by the first air pressure sensor.

19. The in vivo pressure detection system according to any one of claims 13 to 18, characterized in that: The receiver further includes at least one of a wireless communication module and a display module; wherein the wireless communication module is connected to the processor signal to realize two-way communication between the receiver and an external terminal; The display module is used to perform display operations according to the control of the processor.

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