Constant-speed sample mixing device with closed-loop control

Abstract

The invention relates to the technical field of medical instruments, in particular to a sample constant-speed uniform mixing device with closed-loop control, which comprises a uniform mixing substrate, a swivel bearing, an eccentric wheel, a driving mechanism, a uniform mixing bearing, a cleaning sleeve, a sampling needle and a reaction cup, a through hole is arranged near one end of the uniform mixing substrate, the swivel bearing is arranged in the through hole, and the eccentric wheel is arranged on the inner ring of the swivel bearing; the driving mechanism is used for driving the eccentric wheel to rotate, an eccentric hole is formed near the center of the eccentric wheel, a blending bearing is arranged in the eccentric hole, a cleaning sleeve is arranged on an inner ring of the blending bearing, an open hole is formed in the center of the cleaning sleeve, and the sampling needle penetrates through the open hole and vertically slides back and forth along the open hole. The mixing device is simple and reliable in structure, small in size, high in efficiency and not easy to produce more tiny bubbles, and the mixing effect can be accurately controlled, so that the accuracy of a detection result is ensured.

Description

Technical Field

[0001] The invention relates to the technical field of medical devices, and in particular to a sample constant speed mixing device with closed-loop control. Background Art

[0002] In the field of in vitro diagnostic medical devices, specific protein analyzers, coagulation analyzers, biochemical analyzers and other instruments often need to fully mix the collected urine, blood and other body fluid samples before mixing them with reagents to achieve detection accuracy.

[0003] At present, mixing is usually achieved through suction and exhalation of the liquid circuit, paddle stirring, high-frequency eccentric vibration and other methods. These technical methods have some shortcomings. The suction and exhalation method of the liquid circuit will bring bubbles to the mixed liquid, thereby affecting the accuracy of the test results; the paddle stirring method requires a special workstation to be implemented, and a paddle cleaning device must be added, which has a complex structure; the high-frequency eccentric vibration method is difficult to quantify the intensity and amplitude of the vibration, and due to processing errors and assembly errors among various instruments, it is difficult to ensure the consistency of the mixing effect. In addition, when the reaction cup is large, it takes a long time to achieve a good mixing effect.

[0004] Some instruments directly use sampling needles for stirring and mixing. With such a structure, the stirring speed has a great influence on the mixing effect. If the speed is a little slow, the desired mixing effect will not be achieved. If the speed is too fast, bubbles will be generated in the liquid, affecting the test results. Summary of the invention

[0005] The purpose of the present invention is to provide a sample constant speed mixing device with closed-loop control, which solves the technical problems that the existing sample constant speed mixing device with closed-loop control has a complex structure and is difficult to ensure the consistency of the mixing effect when using liquid circuit suction and exhalation, paddle stirring, high-frequency eccentric vibration and sampling needle stirring and mixing, resulting in the accuracy of the detection result being affected.

[0006] To achieve the above-mentioned purpose, the present invention provides a sample constant speed mixing device with closed-loop control, comprising a mixing substrate, a rotating bearing, an eccentric wheel, a driving mechanism, a mixing bearing, a cleaning sleeve, a sampling needle and a reaction cup, wherein a through hole is arranged near one end of the mixing substrate, the rotating bearing is installed in the through hole, the inner ring of the rotating bearing is arranged with the eccentric wheel, the driving mechanism is used to drive the eccentric wheel to rotate, an eccentric hole is arranged near the center of the eccentric wheel, the mixing bearing is arranged in the eccentric hole, the inner ring of the mixing bearing is arranged with the cleaning sleeve, an opening is arranged at the center of the cleaning sleeve, the sampling needle passes through the opening and slides back and forth along the opening, the reaction cup is arranged below the sampling needle, and the body fluid sample and reagent collected by the sampling needle are added to the reaction cup.

[0007] Wherein, the driving mechanism includes a motor seat, a motor and a driving wheel. The motor seat is fixedly arranged at the other end of the mixing substrate, the motor is fixedly installed on the motor seat, and the driving wheel is rotatably arranged on the motor shaft of the motor.

[0008] Wherein, a transmission belt is tensioned between the driving wheel and the eccentric wheel, and the driving wheel drives the eccentric wheel to rotate through the transmission belt.

[0009] Wherein, the driving mechanism further includes an induction plate and a rotation speed sensor. The induction plate is fixedly arranged on the driving wheel, and the rotation speed sensor is fixedly installed on the motor seat.

[0010] Wherein, a retaining ring is arranged near the upper end surface of the cleaning sleeve, and the retaining ring is used to limit the position of the cleaning sleeve on the axis.

[0011] Wherein, the sample constant speed mixing device with closed-loop control further comprises a mixing cover plate, and the mixing cover plate is arranged on the mixing base plate and is located above the transmission belt and the driving wheel.

[0012] Wherein, the sample constant speed mixing device with closed-loop control also includes a control system, which is electrically connected to the speed sensor and the motor respectively and is located on a side of the reaction cup away from the sampling needle.

[0013] The present invention provides a sample constant speed mixing device with closed-loop control, wherein a through hole is provided near one end of the mixing substrate, the rotating bearing is installed in the through hole, the inner ring of the rotating bearing is provided with the eccentric wheel, the driving mechanism is used to drive the eccentric wheel to rotate, an eccentric hole is provided near the center of the eccentric wheel, the mixing bearing is provided in the eccentric hole, the inner ring of the mixing bearing is provided with the cleaning sleeve, an opening is provided at the center of the cleaning sleeve, the sampling needle passes through the opening and slides back and forth along the opening, the reaction cup is provided below the sampling needle, the body fluid sample and reagent collected by the sampling needle are added into the reaction cup, the mixing device has a simple and reliable structure, a small size, high efficiency, is not easy to produce a large number of tiny bubbles, and the mixing effect can be accurately controlled, thereby ensuring the accuracy of the detection result. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art are briefly introduced below.

[0015] Figure 1 It is a schematic diagram of the overall structure of a sample constant speed mixing device with closed-loop control according to the first embodiment of the present invention.

[0016] Figure 2 1 is a top view of a sample constant speed mixing device with closed-loop control according to a first embodiment of the present invention.

[0017] Figure 3 The first embodiment of the present invention Figure 2 A-section view.

[0018] Figure 4 It is a schematic structural diagram of an eccentric wheel according to the first embodiment of the present invention.

[0019] In the figure: 1-mixing substrate, 2-rotating bearing, 3-eccentric wheel, 4-mixing bearing, 5-cleaning sleeve, 6-retaining ring, 7-transmission belt, 8-motor seat, 9-motor, 10-driving wheel, 11-speed sensor, 12-sensing sheet, 13-mixing cover, 14-sampling needle, 15-reaction cup, 16-control system, 31-eccentric hole, 51-opening. DETAILED DESCRIPTION

[0020] Embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, but should not be construed as limiting the present invention.

[0021] First embodiment:

[0022] See also Figures 1 to 4 The present invention provides a sample constant speed mixing device with closed-loop control, comprising a mixing substrate 1, a rotating bearing 2, an eccentric wheel 3, a driving mechanism, a mixing bearing 4, a cleaning sleeve 5, a sampling needle 14 and a reaction cup 15, a mixing cover 13 and a control system 16, wherein the driving mechanism comprises a motor base 8, a motor 9, a driving wheel 10, a sensor sheet 12 and a speed sensor 11.

[0023] In this embodiment, the eccentric wheel 3 is driven to rotate by the driving mechanism, so that the sampling needle 14 swings around the axis of the eccentric wheel 3, so as to achieve stirring and mixing of the liquid in the reaction cup 15. While stirring and mixing, the speed of the motor 9 is detected by the speed sensor 11, so that the speed of the motor 9 can be accurately, real-time and constantly controlled according to the volume of the reaction cup 15, the viscosity of the reagent, etc., to achieve accurate and constant control of the speed of mixing and stirring, so that the liquid can be evenly mixed, and closed-loop control can be achieved, and the structure is simple and reliable, the volume is small, the efficiency is high, and it is not easy to produce a large number of tiny bubbles. The mixing effect can be accurately controlled, thereby ensuring the accuracy of the test results, and there is no need to add a special paddle for stirring, which solves the technical problem that the existing sample constant speed mixing device with closed-loop control has a complex structure and is difficult to ensure the consistency of the mixing effect when using liquid path suction and exhalation, paddle stirring, high-frequency eccentric vibration and stirring and mixing of the sampling needle 14, resulting in the accuracy of the test results being affected.

[0024] Among them, a through hole is provided near one end of the mixing substrate 1, and the rotating bearing 2 is installed in the through hole. The inner ring of the rotating bearing 2 is provided with the eccentric wheel 3, and the driving mechanism is used to drive the eccentric wheel 3 to rotate. An eccentric hole 31 is provided near the center of the eccentric wheel 3, and the mixing bearing 4 is provided in the eccentric hole 31. The inner ring of the mixing bearing 4 is provided with the cleaning sleeve 5, and an opening 51 is provided at the center of the cleaning sleeve 5. The sampling needle 14 passes through the opening 51 and slides back and forth along the opening 51. The reaction cup 15 is provided below the sampling needle 14. The body fluid sample and reagent taken by the sampling needle 14 are added to the reaction cup 15. The cleaning sleeve 5 has a liquid inlet and a liquid outlet. When the liquid flows from the liquid inlet of the cleaning sleeve 5 to the liquid outlet of the cleaning sleeve 5 under the action of the pump valve, the cleaning sleeve 5 can realize the cleaning of the outer wall and inner cavity of the sampling needle 14 to prevent cross contamination between samples.

[0025] Secondly, the motor base 8 is fixedly provided at the other end of the mixing substrate 1, the motor base 8 is fixedly mounted with the motor 9, the driving wheel 10 is rotatably provided on the motor shaft of the motor 9, a transmission belt 7 is tensioned between the driving wheel 10 and the eccentric wheel 3, and the driving wheel 10 drives the eccentric wheel 3 to rotate through the transmission belt 7.

[0026] Again, the induction sheet 12 is fixedly provided on the driving wheel 10, and the speed sensor 11 is fixedly installed on the motor seat 8. The speed sensor 11 determines the speed of the motor 9 according to the number of times the induction sheet 12 passes. When the output shaft of the motor 9 rotates, the driving wheel 10 is driven to rotate along the axis of the output shaft of the motor 9, thereby driving the induction sheet 12 to rotate accordingly. When the induction sheet 12 rotates, the speed sensor 11 will sense the number of times the induction sheet 12 passes through it, thereby being able to detect the mixing speed of the motor 9. Afterwards, the speed sensor 11 will feed back the speed signal to the control system 16, so that the control system 16 will compare this speed with the preset speed, and adjust the actual speed of the motor 9 to make it equivalent to the preset speed, thereby realizing closed-loop control of the speed of the motor 9, so that the mixing device can constantly mix according to the preset speed, ensuring that the mixing effect of the sample and the reagent is optimally controlled.

[0027] At the same time, a retaining ring 6 is arranged near the upper end surface of the cleaning sleeve 5, and the retaining ring 6 is used to limit the position of the cleaning sleeve 5 on the axis.

[0028] In addition, the mixing cover plate 13 is arranged on the mixing base plate 1 and is located above the transmission belt 7 and the driving wheel 10 .

[0029] Finally, the control system 16 is electrically connected to the rotation speed sensor 11 and the motor 9 respectively, and is located on a side of the reaction cup 15 away from the sampling needle 14 .

[0030] When using the sample constant speed mixing device with closed-loop control of the present embodiment, after the sampling needle 14 adds the body fluid sample and the reagent into the reaction cup 15, the sampling needle 14 is kept in the reaction cup 15. At this time, the motor 9 starts to run, so that the axis of the output shaft of the motor 9 gradually starts to rotate, thereby driving the driving wheel 10 to rotate along the axis of the output shaft of the motor 9, and then the driving wheel 10 drives the eccentric wheel 3 to rotate through the transmission belt 7. At this time, the cleaning sleeve 5 will swing around the axis of the eccentric wheel 3 due to the eccentric hole 31, and the circumferential shaking radius is the eccentric distance S. When the cleaning sleeve 5 swings in a circle, it will drive the sampling needle 14 to swing in a circle, so that the liquid in the reaction cup 15 can be stirred and mixed. Since the mixing cover plate 13 is arranged above the driving wheel 10, the mixing cover plate 13 can cover the transmission components, thereby achieving a protective and aesthetic effect.

[0031] When the driving wheel 10 rotates along the axis of the output shaft of the motor 9, the rotation of the driving wheel 10 will drive the induction plate 12 to rotate. During the rotation of the induction plate 12, the induction plate 12 will pass through the sensing area of ​​the speed sensor 11. At this time, the speed sensor 11 can determine the speed of the motor 9 according to the number of times the induction plate 12 passes. After that, the speed sensor 11 will feed back the speed signal to the control system 16, so that the control system 16 will compare the speed with the preset speed and adjust the actual speed of the motor 9 to make it equivalent to the preset speed, thereby realizing closed-loop control of the speed of the motor 9, so that the mixing device can constantly mix according to the preset speed, ensuring that the mixing effect of the sample and the reagent is optimally controlled.

[0032] In summary, the eccentric wheel 3 is driven to rotate by the driving mechanism, so that the sampling needle 14 swings around the axis of the eccentric wheel 3, so as to achieve stirring and mixing of the liquid in the reaction cup 15. While stirring and mixing, the speed of the motor 9 is detected by the speed sensor 11, so that the speed of the motor 9 can be accurately, real-time and constantly controlled according to the volume of the reaction cup 15, the viscosity of the reagent, etc., to achieve accurate and constant control of the speed of mixing and stirring, so that the liquid can be evenly mixed, and closed-loop control can be achieved, and the structure is simple and reliable, the volume is small, the efficiency is high, and it is not easy to produce a large number of tiny bubbles. The mixing effect can be accurately controlled, thereby ensuring the accuracy of the test results, and there is no need to add a special paddle for stirring, which solves the technical problem that the existing sample constant speed mixing device with closed-loop control has a complex structure and is difficult to ensure the consistency of the mixing effect when using liquid path suction and exhalation, paddle stirring, high-frequency eccentric vibration and stirring and mixing of the sampling needle 14, resulting in the accuracy of the test results being affected.

[0033] What is disclosed above is only one or more preferred embodiments of the present application, and cannot be used to limit the scope of rights of the present application. Ordinary technicians in this field can understand that all or part of the processes of implementing the above embodiments and equivalent changes made according to the claims of the present application are still within the scope covered by the present application.

Claims

1. A sample constant speed mixing device with closed-loop control, comprising a mixing substrate, characterized in that: It also includes a rotating bearing, an eccentric wheel, a driving mechanism, a mixing bearing, a cleaning sleeve, a sampling needle and a reaction cup. A through hole is arranged near one end of the mixing substrate, the rotating bearing is installed in the through hole, the inner ring of the rotating bearing is arranged with the eccentric wheel, the driving mechanism is used to drive the eccentric wheel to rotate, an eccentric hole is arranged near the center of the eccentric wheel, the mixing bearing is arranged in the eccentric hole, the inner ring of the mixing bearing is arranged with the cleaning sleeve, an opening is arranged at the center of the cleaning sleeve, the sampling needle passes through the opening and slides back and forth along the opening, the reaction cup is arranged below the sampling needle, and the body fluid sample and reagent collected by the sampling needle are added into the reaction cup.

2. The sample constant speed mixing device with closed-loop control as claimed in claim 1, characterized in that: The driving mechanism comprises a motor seat, a motor and a driving wheel. The motor seat is fixedly arranged at the other end of the mixing substrate, the motor is fixedly mounted on the motor seat, and the driving wheel is rotatably arranged on the motor shaft of the motor.

3. The sample constant speed mixing device with closed-loop control as claimed in claim 2, characterized in that: A transmission belt is tensioned between the driving wheel and the eccentric wheel, and the driving wheel drives the eccentric wheel to rotate through the transmission belt.

4. The sample constant speed mixing device with closed-loop control as claimed in claim 3, characterized in that: The driving mechanism further comprises an induction sheet and a rotation speed sensor. The induction sheet is fixedly arranged on the driving wheel, and the rotation speed sensor is fixedly installed on the motor seat.

5. The sample constant speed mixing device with closed-loop control as claimed in claim 1, characterized in that: A retaining ring is arranged near the upper end surface of the cleaning sleeve, and the retaining ring is used for limiting the position of the cleaning sleeve on the axis.

6. The sample constant speed mixing device with closed-loop control as claimed in claim 3, characterized in that: The sample constant speed mixing device with closed-loop control further comprises a mixing cover plate, which is arranged on the mixing base plate and is located above the transmission belt and the driving wheel.

7. The sample constant speed mixing device with closed-loop control as claimed in claim 4, characterized in that: The sample constant speed mixing device with closed-loop control also includes a control system, which is electrically connected to the speed sensor and the motor respectively and is located on a side of the reaction cup away from the sampling needle.

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