Sample detection apparatus

Abstract

The invention discloses sample detection equipment which comprises a sample detection module, the sample detection module comprises a rack, a rotary driving mechanism and a lifting mechanism, the rack comprises a vertical plate and a mounting seat, and the mounting seat is arranged on one side of the vertical plate and used for supporting a sample detection box; the rotary driving mechanism is arranged on the lower side of the mounting seat and is used for driving the rotary valve of the sample detection box to rotate, so that a liquid relief hole in the rotary valve can be communicated with any liquid storage cavity of the sample detection box; the lifting mechanism comprises a first lifting driving part, a lifting block and a picking rod, the picking rod is arranged on the lifting block, and the first lifting driving part is used for driving the lifting block to ascend and descend, so that the lifting block drives the picking rod to pick the pipetting plunger in the pipetting hole for pipetting. The sample detection module is compact in structure arrangement and high in function integration level, has the advantages of small size and small occupied space, and greatly improves the space utilization rate.

Description

Sample testing equipment Technical Field

[0001] This invention belongs to the field of sample detection technology, and specifically relates to a sample detection device. Background Technology

[0002] PCR (Polymerase Chain Reaction) is a molecular biology technique used to amplify specific nucleic acid fragments. PCR processing allows for the rapid amplification of target nucleic acid fragments in large quantities, improving diagnostic sensitivity and reducing analytical complexity. Therefore, PCR-based sample detection devices have gradually become the mainstream in vitro diagnostic method due to their high sensitivity, accuracy, and short processing time. However, sample pretreatment, such as extraction, transfer, mixing, and reagent addition, is typically required before testing. This necessitates integrating multiple sample processing mechanisms into the detection device, resulting in a large device size and significant space requirements. Furthermore, the large space required makes high-throughput testing difficult in space-constrained environments, leading to low detection efficiency. Summary of the Invention

[0003] In view of the above-mentioned defects or deficiencies, the present invention provides a sample detection device, which aims to solve the technical problems of existing sample detection devices being large in size and occupying a lot of space.

[0004] To achieve the above objectives, the present invention provides a sample detection device, which includes a sample detection module, the sample detection module comprising:

[0005] The frame includes an upright plate and a mounting base, the mounting base being located on one side of the upright plate and used to support the sample detection box;

[0006] A rotary drive mechanism is located on the lower side of the mounting base and is used to drive the rotary valve of the sample detection box to rotate so that the pipetting orifice on the rotary valve can communicate with any liquid storage chamber of the sample detection box.

[0007] The lifting mechanism includes a first lifting drive, a lifting block, and a pickup rod. The pickup rod is mounted on the lifting block. The first lifting drive is used to drive the lifting block to move up and down, so that the lifting block can drive the pickup rod to pick up the pipetting plunger in the pipetting orifice and perform pipetting.

[0008] In this embodiment of the invention, the sample detection module further includes a pushing component, which includes a sliding seat and a pushing chamber door. The sliding seat is slidably disposed on the mounting base and is used for placing the sample detection box. The lower end of the pushing chamber door is rotatably disposed on the mounting base. The pushing chamber door is connected to the sliding seat and is used to push and pull the sliding seat from the loading position to the pretreatment position. When the sliding seat is slid to the pretreatment position, the rotation drive mechanism is connected to the rotary valve drive, and the pickup rod is set with a corresponding pipetting hole (202).

[0009] In this embodiment of the invention, the lifting mechanism further includes a lifting door buckle plate, which is disposed on the lifting block and has a door buckle. The upper end of the pushing door is provided with a connecting buckle. When the sliding seat slides to the pre-processing position, the door buckle is used to engage with the connecting buckle (621).

[0010] In this embodiment of the invention, the sliding seat includes a sliding plate and a transition plate. The sliding plate is slidably disposed on the mounting base and is used for placing the sample detection box. The transition plate is connected to the sliding plate and is bent downward from the sliding plate. The push chamber door includes a door panel and a connecting plate disposed at the lower end of the door panel. The connecting plate is rotatably disposed on the mounting base, and a connecting groove for the transition plate to extend into is formed on the connecting plate.

[0011] In this embodiment of the invention, the mounting base is provided with a mounting post, the connecting plate is provided with a mounting sleeve, the mounting sleeve is rotatably sleeved on the mounting post, and a torsion spring is sleeved on the mounting sleeve, the two torsion arms of the torsion spring are respectively connected to the mounting base and the door panel one by one;

[0012] And / or, a pressing block is provided on the side of the door panel facing the upright panel, the pressing block being used to abut against the sample detection box.

[0013] In this embodiment of the invention, the sample detection module further includes a detection device, which includes a housing, a temperature control mechanism, and a detection mechanism disposed within the housing for detecting the reaction tube of the sample detection box. The housing is disposed on the side of the upright plate facing away from the mounting base and has an insertion port. The temperature control mechanism includes a heating element and two heat-conducting blocks spaced apart within the housing. An insertion gap communicating with the insertion port is formed between the two heat-conducting blocks, and each heat-conducting block has a heating element on the side facing the insertion gap. When the sliding seat slides to the pretreatment position, the reaction tube passes through the insertion port and extends into the insertion gap.

[0014] In this embodiment of the invention, a guide wall is formed on the side of the heat-conducting block facing the insertion gap. The guide wall is inclined from bottom to top towards the insertion gap. The temperature control mechanism also includes a pushing component and a resetting component. The pushing component includes a push block that extends into the insertion gap. The lifting mechanism also includes a lifting push-pull plate disposed on the lifting block. The lifting push-pull plate is connected to the push block and is used to drive the push block to slide along the extension direction of the guide wall, so that the push block pushes the two heat-conducting blocks to move in opposite directions. The resetting component includes a first spring disposed between the housing and the heat-conducting block. The two ends of the first spring respectively abut against the housing and the heat-conducting block.

[0015] In this embodiment of the invention, the pushing component further includes a sliding plate and a push-pull rod. The sliding plate is disposed inside the housing, and the push block and push-pull rod are disposed on both sides of the sliding plate. A sliding groove is provided on the housing, and a locking hole is provided on the lifting push-pull plate. The push-pull rod can slide through the sliding groove and extend into the locking hole. The push block is connected to the lifting push-pull plate through the sliding plate and the push-pull rod.

[0016] In this embodiment of the invention, the reset assembly further includes a first mounting rod, a first mounting groove is provided on the side of the heat-conducting block facing away from the guide wall, the first mounting rod is disposed on the housing and extends into the first mounting groove, and a first spring is sleeved on the first mounting rod.

[0017] In this embodiment of the invention, the temperature control mechanism further includes a heat dissipation component, which includes a heat sink, a heat pipe, and a cooling fan. The heat sink is disposed inside the housing and spaced apart from the heat pipe. The two ends of the heat pipe are respectively embedded in the heat pipe and the heat sink. The cooling fan is disposed on one side of the heat sink and located between the heat pipe and the heat sink.

[0018] In this embodiment of the invention, the rotary drive mechanism includes a rotary drive component and a rotary locking pin. The rotary drive component is located on the lower side of the mounting base, and the mounting base has a mounting hole for the rotary locking pin to pass through. One end of the rotary locking pin is driven to connect with the rotary drive component, and the other end of the rotary locking pin has a locking protrusion. When the sliding seat slides to the pre-processing position, the locking protrusion engages with the locking groove of the rotary valve.

[0019] In this embodiment of the invention, the sample detection module further includes a magnetic attraction mechanism, which includes a second lifting drive and a magnetic block. The second lifting drive is disposed on the mounting base and drivenly connected to the magnetic block. The mounting base has a through hole for the magnetic block to pass through.

[0020] In this embodiment of the invention, the sample detection module further includes a heating component, which includes a connecting bracket and a heating block. The connecting bracket is disposed on the frame, and the heating block is disposed on the connecting bracket and is used to fit with the sample detection box.

[0021] In this embodiment of the invention, the sample detection device further includes a housing, and the number of sample detection modules is set to multiple, with the multiple sample detection modules arranged sequentially inside the housing. The housing has placement openings for placing sample detection boxes, and the number of placement openings is consistent with the number of sample detection modules and is set one-to-one.

[0022] Through the above technical solutions, the sample detection device provided in the embodiments of the present invention has the following beneficial effects:

[0023] In the technical solution of this invention, one side of the upright plate is provided with a mounting base for supporting the sample detection box, a rotary drive mechanism for driving the rotary valve to rotate, and a lifting mechanism for picking up and moving the pipette plunger. Through the cooperation of the rotary drive mechanism and the lifting mechanism, the sample in the sample detection box can be pre-treated by extraction, pipetting, and mixing. The sample detection module has a compact structure and high functional integration, with the advantages of small size and small space occupation, which greatly improves the space utilization rate. Moreover, when it is necessary to test the sample, it is only necessary to place the sample detection box in the sample detection equipment so that the sample detection box is supported on the mounting base. The sample in the sample detection box can be processed by the rotary drive mechanism and the lifting mechanism, eliminating manual operation, reducing the risk of impurities and contaminants entering the sample detection box and causing sample contamination, and improving the accuracy of the test results.

[0024] Other features and advantages of the embodiments of the present invention will be described in detail in the following detailed description section. Attached Figure Description

[0025] The accompanying drawings are provided to further illustrate embodiments of the present invention and form part of the specification. They are used together with the following detailed description to explain the embodiments of the present invention, but do not constitute a limitation thereof. Those skilled in the art can obtain other drawings based on the structures shown in these drawings without any inventive effort. In the drawings:

[0026] Figure 1 is a schematic diagram of a sample detection device according to an embodiment of the present invention;

[0027] Figure 2 is a schematic diagram of the closed push chamber door in a sample detection module according to an embodiment of the present invention;

[0028] Figure 3 is a schematic diagram of the opening structure of the push chamber door in a sample detection module according to an embodiment of the present invention;

[0029] Figure 4 is a structural schematic diagram of the push-pull compartment door and the lifting door buckle plate according to an embodiment of the present invention;

[0030] Figure 5 is a structural schematic diagram of the mounting base and the pushing component according to an embodiment of the present invention;

[0031] Figure 6 is a structural schematic diagram of the frame, lifting mechanism, detection device and heating assembly according to an embodiment of the present invention;

[0032] Figure 7 is a schematic diagram of the structure of a detection device according to an embodiment of the present invention;

[0033] Figure 8 is a structural schematic diagram of a temperature control mechanism according to an embodiment of the present invention;

[0034] Figure 9 is a schematic diagram of the structure of the pushing component and the resetting component according to an embodiment of the present invention;

[0035] Figure 10 is a structural schematic diagram of the frame, lifting mechanism and magnetic attraction mechanism according to an embodiment of the present invention;

[0036] Figure 11 is a structural schematic diagram of the side plate and lifting mechanism according to an embodiment of the present invention;

[0037] Figure 12 is a structural schematic diagram of a mounting base and a magnetic attraction mechanism according to an embodiment of the present invention;

[0038] Figure 13 is a schematic diagram of a rotary drive mechanism according to an embodiment of the present invention;

[0039] Figure 14 is a schematic diagram of the assembly structure of a sample detection box according to an embodiment of the present invention;

[0040] Figure 15 is an exploded structural diagram of a sample detection box according to an embodiment of the present invention.

[0041] Explanation of reference numerals in the attached figures

[0042] 10 Sample Detection Module 5511 Second Mounting Slot

[0043] 20 racks 552 sliding plate

[0044] 21. Vertical panel 553. Push-pull rod.

[0045] 22 Mounting base 56 Reset assembly

[0046] 221 Mounting post 561 First spring

[0047] 222 Mounting hole 562 First mounting rod

[0048] 223 Through hole 563 Second spring

[0049] 224 Second guide groove 564 Second mounting rod

[0050] 23 Side Panel 57 Heat Dissipation Components

[0051] 231 First Sensor 571 Heatsink

[0052] 232 Second sensor 5711 Heat sink fins

[0053] 233 Third sensor 572 Heat pipe

[0054] 234 Fourth sensor 573 Cooling fan

[0055] 24 Top Plate 60 Push Components

[0056] 25 Enclosure Panels 61 Sliding Seats

[0057] 251 First guide groove 611 Sliding plate

[0058] 26 Fixing plate 6111 Placement slot

[0059] 30 Rotary drive mechanism 6112 Clearance hole

[0060] 31 Rotary drive component 612 Adapter plate

[0061] 32 Rotating locking pins 62 Pushing door

[0062] 321 Snap-fit ​​protrusion; 621 Connecting buckle

[0063] 40 Lifting mechanism 622 Door panel

[0064] 41 First lifting drive component 6221 Pressing block

[0065] 42 Lifting block 623 Connecting plate

[0066] 421 First baffle plate 6231 Connecting groove

[0067] 43 Pick-up lever 6232 Mounting sleeve

[0068] 44 Lifting door latch plate 6233 Torsion spring

[0069] 441 Door latch 70 Magnetic closure mechanism

[0070] 442 Lifting Unit 71 Second Lifting Drive Component

[0071] 443 Guide section 72 Magnetic block

[0072] 444 Second baffle 73 Mounting bracket

[0073] 45 Lifting and sliding panel; 74 Adapter block

[0074] 451 Slot 741 Third Stop

[0075] 46 Guide rod 80 Heating assembly

[0076] 50 Detection device 81 Connecting bracket

[0077] 51 Housing 82 Heating Block

[0078] 511 Socket 83 Insulation Block

[0079] 512 Slide Groove 84 Elastic Sheet

[0080] 513 Mounting Ear 90 Cover

[0081] 52 Testing institutions 91 Placement port

[0082] 53 Heating element 200 Sample detection kit

[0083] 54 Heat-conducting block 201 Rotary valve

[0084] 541 Insertion gap 2011 Card slot

[0085] 542 Guide Wall 2012 Pipetting Channel

[0086] 543 First mounting slot 202 Pipetting hole

[0087] 55. Actuating component 203. Liquid storage chamber.

[0088] 551 Pusher block 204 Reaction tube Detailed Implementation

[0089] The specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit the present invention.

[0090] The sample testing device of the present invention will now be described with reference to the accompanying drawings.

[0091] As shown in Figures 2 and 3, the present invention provides a sample detection device, which includes a sample detection module 10. The sample detection module 10 includes a frame 20, a rotary drive mechanism 30, a lifting mechanism 40, and a detection device 50. The frame 20 includes a vertical plate 21 and a mounting base 22. The mounting base 22 is located on one side of the vertical plate 21 and is used to support the sample detection box 200. The rotary drive mechanism 30 is located on the lower side of the mounting base 22 and is used to drive the rotary valve 201 of the sample detection box 200 to rotate, so that the pipetting orifice 202 on the rotary valve 201 can communicate with any liquid storage chamber 203 of the sample detection box 200. The lifting mechanism 40 includes a first lifting drive component 41, a lifting block 42, and a pickup rod 43. The pickup rod 43 is located on the lifting block 42. The first lifting drive component 41 is used to drive the lifting block 42 to rise and fall, so that the lifting block 42 drives the pickup rod 43 to pick up the pipetting plunger in the pipetting orifice 202 and perform pipetting.

[0092] It should be noted that the sample detection device of this embodiment can process and detect the sample in the sample detection box 200. As shown in Figures 14 and 15, the sample detection box 200 has multiple liquid storage chambers 203, which are used to hold samples, eluents, reagents, etc. The sample detection box 200 is provided with a rotary valve 201, which has a pipetting orifice 202 and a pipetting channel 2012 communicating with the pipetting orifice 202. A groove 20 is formed on the lower side of the rotary valve 201. 11. By rotating the rotary valve 201, the pipetting channel 2012 can be connected to any one of the liquid storage chambers 203, thereby allowing the pipetting orifice 202 to be connected to any one of the liquid storage chambers 203 through the pipetting channel 2012. A pipetting plunger is placed inside the pipetting orifice 202. A reaction tube 204 is provided on the outside of the sample detection box 200, and the reaction tube 204 is connected to one of the liquid storage chambers 203. By placing the sample detection box 200 inside the sample detection device, the sample can be processed and detected.

[0093] Specifically, a rotary drive mechanism 30, a mounting base 22, and a lifting mechanism 40 are sequentially arranged from bottom to top on one side of the upright plate 21. The mounting base 22 supports the sample detection box 200 so that the rotary drive mechanism 30 can drive the rotary valve 201 of the sample detection box 200 to rotate from the lower side of the mounting base 22, so that the pipetting orifice 202 communicates with any one of the liquid storage chambers 203. The lifting mechanism 40 includes a lifting block 42, a pickup rod 43 connected to the lifting block 42, and a first lifting drive member 41 for driving the lifting block 42 to move up and down. The first lifting drive member 41 drives the lifting block 42 to descend so that the pickup rod 43 moves from the pipetting orifice 202 to the liquid storage chamber 203. The pipette is picked up from the liquid orifice 202. Then, the first lifting drive 41 drives the lifting block 42 to rise so that the pick rod 43 drives the pipette to rise and draw the liquid in the storage chamber 203 into the pipette orifice 202 to realize the pipetting. Then, the rotary drive mechanism 30 drives the rotary valve 201 to rotate so that the pipette orifice 202 is connected to multiple storage chambers 203 respectively. The pick rod 43 drives the pipette to rise and fall to realize sample extraction, pipetting and mixing and other pretreatment. After the sample pretreatment is completed, the pick rod 43 drives the pipette to fall to inject the sample in the pipette orifice 202 into the reaction tube 204.

[0094] In the sample detection module 10 of this embodiment, one side of the upright plate 21 is provided with a mounting base 22 for supporting the sample detection box 200, a rotary drive mechanism 30 for driving the rotary valve 201 to rotate, and a lifting mechanism 40 for picking up the pipette plunger and driving the pipette plunger to rise and fall. Through the cooperation of the rotary drive mechanism 30 and the lifting mechanism 40, the sample in the sample detection box 200 can be pre-treated by extraction, pipetting, and mixing. The sample detection module 10 has a compact structure and high functional integration, and has the advantages of small size and small space occupation, which greatly improves the space utilization rate. Moreover, when it is necessary to test the sample, it is only necessary to place the sample detection box 200 in the sample detection equipment so that the sample detection box 200 is supported on the mounting base 22. The sample in the sample detection box 200 can be processed by the rotary drive mechanism 30 and the lifting mechanism 40, which eliminates manual operation, reduces the risk of impurities and contaminants entering the sample detection box 200 and causing sample contamination, and improves the accuracy of the test results.

[0095] In this embodiment of the invention, as shown in Figures 2, 3, 6, 10, and 11, the frame 20 further includes a side plate 23 and a top plate 24. An upright plate 21 is located on one side of the side plate 23, and the top plate 24 is located at the upper end of the upright plate 21. The first lifting drive component 41 can be a lead screw motor as used in the prior art. The first lifting drive component 41 is mounted on the top plate 24, and the drive screw of the first lifting drive component 41 extends downward through the top plate 24. The lifting block 42 is sleeved on the drive screw of the first lifting drive component 41 and threadedly connected to the drive screw, so that the first lifting drive component 41 can drive the lifting block 42 to rise and fall. A fixing plate 26 is provided on the upright plate 21 on the same side as the mounting base 22. A guide rod 46 is provided on the fixing plate 26. The guide rod 46 extends upward and passes through the lifting block 42. The guide rod 46 guides the lifting block 42 to move up and down, improving the smoothness of the lifting block 42. In addition, the lifting block 42 is provided with a first baffle 421, and the side plate 23 is provided with a first sensor 231 for detecting the position information of the first baffle 421. When the first lifting drive 41 drives the lifting block 42 to rise to the initial position, the first sensor 231 can detect the position information of the first baffle 421. Then, based on the detection result of the first sensor 231, it can be determined that the lifting block 42 drives the pickup rod 43 to rise above the fixed plate 26, which is convenient for placing the sample detection box 200 and effectively prevents interference between the pickup rod 43 and the sample detection box 200.

[0096] In this embodiment of the invention, the sample detection module 10 further includes a pushing component 60, which includes a sliding seat 61 and a pushing chamber door 62. The sliding seat 61 is slidably disposed on the mounting base 22 and is used for placing the sample detection box 200. The lower end of the pushing chamber door 62 is rotatably disposed on the mounting base 22. The pushing chamber door 62 is connected to the sliding seat 61 and is used to push and pull the sliding seat 61 from the loading position to the pretreatment position. When the sliding seat 61 is slid to the pretreatment position, the rotation drive mechanism 30 is driven to connect with the rotary valve 201, and the pickup rod 43 is set corresponding to the pipetting hole 202.

[0097] As shown in Figures 2 to 5, when the sample detection box 200 needs to be placed, the push door 62 rotates away from the mounting base 22 to pull the sliding base 61 away from the upright plate 21 to the loading position, thus facilitating the placement of the sample detection box 200 on the sliding base 61. After the sample detection box 200 is placed stably, the push door 62 is pushed towards the mounting base 22 to push the sliding base 61 to slide above the mounting base 22, so that the sliding base 61 is in the pre-processing position. The mounting base 22 stably supports the sample detection box 200 on the sliding base 61, which facilitates the rotation drive mechanism 30 and the lifting mechanism 40 to perform pre-processing such as extraction, transfer and mixing of the sample in the sample detection box 200. The rotation of the push door 62 pushes and pulls the sliding base 61 to shorten the sliding stroke of the sliding base 61, reduces the lateral space occupied by the sample detection module 10, and further improves the space utilization rate.

[0098] In this embodiment of the invention, the lifting mechanism 40 further includes a lifting door buckle plate 44, which is disposed on the lifting block 42 and is provided with a door buckle 441. The upper end of the pushing door 62 is provided with a connecting buckle 621 that engages with the door buckle 441. When the sliding seat 61 slides to the pre-processing position, the door buckle 441 is used to engage with the connecting buckle 621. As shown in Figures 2 to 5, the lifting block 42 can drive the lifting door buckle plate 44 to rise and fall, and the push chamber door 62 rotates towards the mounting base 22 to push the sliding base 61 to slide to the pre-processing position, so that the mounting base 22 stably supports the sample detection box 200 on the sliding base 61. The first lifting drive component 41 drives the lifting block 42 to fall, so that the lifting block 42 drives the lifting door buckle plate 44 to fall. The chamber door buckle 441 on the lifting door buckle plate 44 falls down to engage with the connecting buckle 621 on the push chamber door 62, so as to restrict the rotation of the push chamber door 62, so that the push chamber door 62 can block one side of the sample detection box 200 to prevent impurities, contaminants, etc. from entering the sample detection box 200 and contaminating the sample. Understandably, the lifting door latch plate 44 is movably supported on the lifting block 42, and the upper end of the lifting door latch plate 44 passes through the top plate 24, so that the lifting block 42 can still descend relative to the lifting door latch plate 44 when the door latch 441 and the connecting latch 621 are engaged, thereby driving the pickup rod 43 to descend. The lifting stroke of the lifting door latch plate 44 and the lifting stroke of the pickup rod 43 do not interfere with each other, and the structural design is reasonable.

[0099] Further, as shown in Figures 3, 4, 10, and 11, the lifting door latch 44 includes a lifting part 442 and a guide part 443. The lifting part 442 is movably supported on the lifting block 42 and its upper end passes through the top plate 24. The guide part 443 is connected to the lower end of the lifting part 442 and extends downward. The door latch 441 is provided on the guide part 443 and is used to engage with the connecting latch 621 to restrict the rotation of the push door 62. The upright plate 21 is also provided with two surrounding plates 25 arranged on the same side as the mounting base 22, and the two surrounding plates 25 are spaced apart in the left-right direction. One of the surrounding plates 25 has a first opening. A guide groove 251 is provided, and the lower end of the guide part 443 extends into the first guide groove 251 and slides in cooperation with the first guide groove 251. The first guide groove 251 plays the role of guiding the lifting door buckle plate 44 to move up and down, thereby improving the smoothness of the lifting door buckle plate 44. In addition, a second baffle 444 is provided on the lifting part 442, and a second sensor 232 for detecting the position information of the second baffle 444 is provided on the side plate 23. According to the detection result of the second sensor 232, it can be determined that the door buckle 441 is engaged with the connecting buckle 621, thereby determining that the push door 62 is protected on one side of the sample detection box 200.

[0100] In this embodiment of the invention, the sliding seat 61 includes a sliding plate 611 and a connecting plate 612. The sliding plate 611 is slidably disposed on the mounting base 22 and is used for placing the sample detection box 200. The connecting plate 612 is connected to the sliding plate 611 and is bent downward from the sliding plate 611. The push chamber door 62 includes a door panel 622 and a connecting plate 623 disposed at the lower end of the door panel 622. The connecting plate 623 is rotatably disposed on the mounting base 22, and a connecting groove 6231 for the connecting plate 612 to extend into is formed on the connecting plate 623.

[0101] As shown in Figures 2 to 5, the door panel 622 can drive the connecting plate 623 to rotate relative to the mounting base 22, so that the connecting plate 623 pushes and pulls the adapter plate 612 through the connecting groove 6231, thereby causing the adapter plate 612 to push and pull the sliding plate 611 to slide relative to the mounting base 22. When the door panel 622 drives the sliding plate 611 to a position away from the upright plate 21, the sample detection box 200 can be placed on the sliding plate 611, which is convenient and quick to install. The sliding plate 611 has a placement groove 6111 for the sample detection box 200 to extend into. The placement groove 6111 plays the role of positioning and installing the sample detection box 200, improving the placement stability. Furthermore, when the door panel 622 drives the sliding plate 611 to slide above the mounting base 22, the door panel 622, the fixing plate 26, and the two surrounding plates 25 cooperate to surround the outside of the sample detection box 200, effectively preventing impurities, contaminants, etc. from entering the sample detection box 200 and contaminating the sample, thus improving the accuracy of the test results.

[0102] In this embodiment of the invention, the mounting base 22 is provided with a mounting post 221, and the connecting plate 623 is provided with a mounting sleeve 6232. The mounting sleeve 6232 is rotatably sleeved on the mounting post 221, and a torsion spring 6233 is sleeved on the mounting sleeve 6232. The two torsion arms of the torsion spring 6233 are respectively connected to the mounting base 22 and the door panel 622. As shown in Figures 2 to 5, the mounting sleeve 6232 is used for the mounting post 221 to extend into, and the mounting sleeve 6232 can rotate relative to the mounting post 221, so that the door panel 622 can drive the connecting plate 623 to rotate relative to the mounting base 22, thereby pushing and pulling. The sliding plate 611 slides, and a torsion spring 6233 is sleeved on the outside of the mounting sleeve 6232. When the door latch 441 is engaged with the connecting latch 621, the door plate 622 and the mounting base 22 cooperate to compress the torsion spring 6233. When the door latch 441 rises and releases the limit on the door plate 622, the elastic restoring force of the torsion spring 6233 acts on the door plate 622, causing the door plate 622 to rotate away from the mounting base 22 and pull the sliding plate 611 to slide away from the upright plate 21, thereby facilitating the placement of the sample detection box 200 on the sliding plate 611 and improving the degree of automation.

[0103] In this embodiment of the invention, the sample detection module 10 further includes a detection device 50, which includes a housing 51, a temperature control mechanism, and a detection mechanism 52 disposed in the housing 51 for detecting the reaction tube 204 of the sample detection box 200. The housing 51 is disposed on the side of the upright plate 21 facing away from the mounting base 22 and has an insertion port 511 for the reaction tube 204 to extend into. The temperature control mechanism includes a heating element 53 and two heat-conducting blocks 54 spaced apart in the housing 51. An insertion gap 541 communicating with the insertion port 511 is formed between the two heat-conducting blocks 54, and each heat-conducting block 54 has a heating element 53 on the side facing the insertion gap 541. When the sliding base 61 slides to the pretreatment position, the reaction tube 204 passes through the insertion port 511 and extends into the insertion gap 541.

[0104] As shown in Figures 6 to 9, a detection device 50 is provided on the other side of the upright plate 21. The reaction tube 204 can pass through the upright plate 21 and extend into the detection device 50. The detection device 50 is used to perform multiple heating and cooling processes on the reaction tube 204 and to detect the sample after processing in the reaction tube 204. The detection device 50 includes a housing 51 and a temperature control mechanism and a detection mechanism 52 disposed in the housing 51. The temperature control mechanism includes two spaced heat-conducting blocks 54, with an insertion gap 541 formed between the two heat-conducting blocks 54. The temperature control mechanism also includes heating elements 53. The number of heating elements 53 is the same as that of the heat-conducting blocks 54, and they are disposed on the side of the heat-conducting blocks 54 facing the insertion gap 541. An insertion port 511 is provided on the housing 51, which communicates with the insertion gap 541. The detection mechanism 52 is disposed on the side of the heat-conducting block 54 away from the insertion port 511. The push-pull door 62 slides the sliding seat 61 to the pre-processing position, allowing the reaction tube 204 on the sample detection box 200 to be inserted from the insertion port 511 into the insertion gap 541. This allows the two heating plates 53 to be attached to both sides of the reaction tube 204 to heat the reaction tube 204. The heat generated by the heating plates 53 can be quickly conducted to the heat-conducting block 54 after heating to cool the reaction tube 204. This achieves cyclic heating and cooling of the sample to be tested in the reaction tube 204. The detection mechanism 52 can detect the sample in the reaction tube 204 after the sample heating and cooling process is completed to quickly obtain the detection results. It has a high degree of functional integration and occupies little space. The sample detection module 10 can process and detect the samples in the sample detection box 200 through the rotary drive mechanism 30, the lifting mechanism 40 and the detection device 50, realizing a rapid detection mode of sample entry and result exit. The detection time is short, the detection efficiency is improved, and the detection automation degree is high, eliminating manual operation, reducing the risk of impurities and contaminants entering the sample detection box 200 and causing sample contamination, and improving the accuracy of the detection results.

[0105] In this embodiment of the invention, a guide wall 542 is formed on the side of the heat-conducting block 54 facing the insertion gap 541. The guide wall 542 is inclined from bottom to top towards the insertion gap 541. The temperature control mechanism also includes a pushing component 55 and a resetting component 56. The pushing component 55 includes a push block 551 extending into the insertion gap 541. The lifting mechanism 40 also includes a lifting push-pull plate 45 disposed on the lifting block 42. The lifting push-pull plate 45 is connected to the push block 551 and is used to drive the push block 551 to slide along the extension direction of the guide wall 542, so that the push block 551 pushes the two heat-conducting blocks 54 to move in opposite directions. The resetting component 56 includes a first spring 561 disposed between the housing 51 and the heat-conducting block 54. The two ends of the first spring 561 respectively abut against the housing 51 and the heat-conducting block 54.

[0106] As shown in Figures 6 to 9, the lifting block 42 can drive the lifting push-pull plate 45 to rise and fall. Two heat-conducting blocks 54 are spaced apart in the housing 51 in the left and right direction. A guide wall 542 extending in the up and down direction is formed on the side of the heat-conducting block 541 facing the insertion gap 541. The guide wall 542 is inclined in the insertion gap 541 from bottom to top. The push block 551 is installed in the insertion gap 541 and can slide along the extension direction of the guide wall 542. The lifting push-pull plate 45 is connected to the push block 551 and is used to drive the push block 551 to slide. When the reaction tube 204 containing the sample to be tested is inserted from the insertion port 511 into the insertion gap 541, the first lifting drive 41 drives the lifting block 42 to rise, so that the lifting block 42 drives the lifting push-pull plate 45 to pull the push block 551 upward. The push block 551 slides from the lower end to the upper end of the guide wall 542, so that the push block 551 pushes the two heat conducting blocks 54 to move in opposite directions through the guide wall 542. The insertion gap 541 between the two heat conducting blocks 54 increases, so that the reaction tube 204 will not rub against the heating element 53 during the process of extending into the insertion gap 541, thus extending the service life of the heating element 53 and greatly reducing the frequency of maintenance and replacement of the heating element 53.

[0107] Furthermore, the heating element 53 is positioned corresponding to the insertion port 511, and the guide wall 542 is spaced apart from the heating element 53 in the vertical direction. One end of the first spring 561 abuts against the housing 51, and the other end of the first spring 561 abuts against the heat-conducting block 54. When the reaction tube 204 is inserted into place, the heat-conducting block 54 and the housing 51 cooperate to compress the first spring 561. The first lifting drive 41 drives the lifting block 42 to descend, so that the lifting block 42 pushes the push block 551 downward through the lifting push-pull plate 45. When the first spring 561 moves, the elastic restoring force acts on the heat-conducting block 54, causing the two heat-conducting blocks 54 to move towards each other, reducing the insertion gap 541 between the two heat-conducting blocks 54. This causes the two heating elements 53 to respectively adhere to both sides of the reaction tube 204 to heat the reaction tube 204. The heat generated by the heating elements 53 can be quickly conducted to the heat-conducting block 54 after heating to cool the reaction tube 204, thus realizing the cyclic heating and cooling process of the sample to be tested in the reaction tube 204.

[0108] Understandably, the lifting and sliding plate 45 is movably supported on the lifting block 42, and the upper end of the lifting and sliding plate 45 passes through the top plate 24, so that the lifting block 42 can still descend relative to the lifting and sliding plate 45 when the heating element 53 is in contact with the reaction tube 204, thereby driving the pickup rod 43 to descend. The lifting stroke of the lifting and sliding plate 45 and the lifting stroke of the pickup rod 43 do not interfere with each other, and the structural design is reasonable.

[0109] In this embodiment of the invention, the pushing component 55 further includes a sliding plate 552 and a push-pull rod 553. The sliding plate 552 is disposed inside the housing 51. The push block 551 and the push-pull rod 553 are disposed on both sides of the sliding plate 552. A sliding groove 512 is provided on the housing 51. A locking hole 451 is provided on the lifting push-pull plate 45. The push-pull rod 553 can slide through the sliding groove 512 and extend into the locking hole 451. The push block 551 is connected to the lifting push-pull plate 45 through the sliding plate 552 and the push-pull rod 553.

[0110] As shown in Figures 6 to 11, a push block 551 is provided on one side of the sliding plate 552. The push block 551 extends into the insertion gap 541 and slides in cooperation with the guide wall 542. A push-pull rod 553 is provided on the other side of the sliding plate 552 and extends out of the housing 51 through the sliding groove 512 on the housing 51. The sliding groove 512 extends in the vertical direction, and the push-pull rod 553 extends into the locking hole 451 of the lifting push-pull plate 45 to connect with the lifting push-pull plate 45. The lifting push-pull plate 45 drives the push-pull rod 553 to slide upward along the sliding groove 512, so that the push-pull rod 553 drives the push block 551 to self-guide through the sliding plate 552. The lower end of the guide wall 542 slides upward, thereby causing the pusher block 551 to push the two heat-conducting blocks 54 to move in opposite directions to prevent wear on the heating element 53 when the reaction tube 204 is inserted; and, the pusher block 553 is driven to slide downward along the slide groove 512 by the lifting pusher plate 45, so that the pusher block 551 is driven to slide from the upper end to the lower end of the guide wall 542 by the sliding plate 552, thereby causing the two heat-conducting blocks 54 to move towards each other to the contact position under the elastic restoring force of the corresponding first spring 561, so that the heating element 53 is in contact with and presses the reaction tube 204 to improve the uniformity of heating and improve the heating effect.

[0111] In this embodiment of the invention, multiple push blocks 551 are provided, and these push blocks 551 are spaced apart on the sliding plate 552. A guide wall 542 is formed on each heat-conducting block 54 corresponding to the position of each push block 551. As shown in Figures 8 and 9, the sliding plate 552 has two push blocks 551 spaced apart in the vertical direction on the side facing the inside of the housing 51. Each heat-conducting block 54 has a guide wall 542 corresponding to the position of each push block 551, so that by pushing and pulling the sliding plate 552, the two push blocks 551 can be driven to slide synchronously along the corresponding guide wall 542, thereby improving the smoothness and stability of the two heat-conducting blocks 54 moving towards or away from each other. Furthermore, the push blocks 551 are wedge-shaped, and the two heat-conducting blocks 54... Each position corresponding to the pusher 551 has a guide wall 542 for sliding engagement with the pusher 551. The wedge-shaped pusher 551 can slide along the guide wall 542 to any position and fit with the guide wall 542 to stably support the heat conduction block 54, which improves the smoothness of the movement of the heat conduction block 54. Furthermore, by pushing the two heat conduction blocks 54 with the wedge-shaped pusher 551, the insertion gap 541 between the two heat conduction blocks 54 can be stably increased, which effectively prevents the reaction tube 204 from wearing the heating plate 53.

[0112] In this embodiment of the invention, the reset assembly 56 further includes a first mounting rod 562. A first mounting groove 543 is formed on the side of the heat-conducting block 54 facing away from the guide wall 542. The first mounting rod 562 is disposed on the housing 51 and extends into the first mounting groove 543. A first spring 561 is sleeved on the first mounting rod 562. As shown in FIG8, one end of the first mounting rod 562 is connected to the housing 51, and the other end of the first mounting rod 562 extends into the first mounting groove 543. The first spring 561 is sleeved on the first mounting rod 562, one end of the first spring 561 abuts against the housing 51, and the other end of the first spring 561 abuts against the heat-conducting block 54. When the lifting and pulling plate 45 drives the push block 551 to push the two heat-conducting blocks 54 to move in opposite directions, the heat-conducting blocks 54 cooperate with the housing 51 to compress the first spring 561. When the reaction tube 204 extends between the two heating plates 53, the lifting and pulling plate 45 drives the push block 551 to slide downward. The elastic restoring force of the first spring 561 acts on the heat-conducting blocks 54, causing the two heat-conducting blocks 54 to move towards each other to a fitting position to heat the reaction tube 204. The elastic restoring force of the first spring 561 can also act on the heating plates 53 through the heat-conducting blocks 54, causing the heating plates 53 to move toward the insertion gap 541 to press the reaction tube 204, improving the heating uniformity of the reaction tube 204 and accelerating the heating rate. Furthermore, the first mounting rod 562 can use fasteners such as screws and pins in the prior art, which is convenient for installation and reduces costs.

[0113] Furthermore, the reset assembly 56 also includes a second mounting rod 564 and a second spring 563. The housing 51 is provided with a mounting ear 513, and the push block 551 is provided with a second mounting groove 5511 along the vertical direction. The second mounting rod 564 is provided on the mounting ear 513 and extends into the second mounting groove 5511. The second spring 563 is sleeved on the second mounting rod 564, and the two ends of the second spring 563 respectively abut against the mounting ear 513 and the push block 551.

[0114] As shown in Figure 9, the housing 51 is provided with a mounting ear 513 extending into the housing 51, and the mounting ear 513 and the heat-conducting block 54 are arranged at intervals in the vertical direction. The push block 551 is provided with a second mounting groove 5511 extending in the vertical direction at the position corresponding to the mounting ear 513. One end of the second mounting rod 564 is connected to the mounting ear 513, and the other end of the second mounting rod 564 extends into the second mounting groove 5511. The second spring 563 is sleeved on the second mounting rod 564, one end of the second spring 563 abuts against the mounting ear 513, and the other end of the second spring 563 abuts against the bottom wall of the second mounting groove 5511. When the lifting and pulling plate 45 drives the push block 551 to push the two heat-conducting blocks 54 to move in opposite directions, the push block 551 cooperates with the mounting ear 513 to squeeze the second spring 563. When the reaction tube 204 extends between the two heating plates 53, the lifting and pulling plate 45 drives the push block 551 to slide downward. The elastic restoring force of the second spring 563 acts on the push block 551, so that the push block 551 can quickly return to its original position, improving the smoothness of the push block 551's return and sliding.

[0115] In this embodiment of the invention, the temperature control mechanism further includes a heat dissipation component 57, which includes a heat sink 571, a heat pipe 572, and a cooling fan 573. The heat sink 571 is disposed inside the housing 51 and spaced apart from the heat conduction block 54. The two ends of the heat conduction pipe 572 are respectively embedded in the heat conduction block 54 and the heat sink 571. The cooling fan 573 is disposed on one side of the heat sink 571 and located between the heat conduction block 54 and the heat sink 571. As shown in Figures 7 and 8, the heating element 53 is located on the side of the heat-conducting block 54 facing the insertion gap 541. The heating element 53 can be a thermoelectric semiconductor heating patch or a Peltier, which can generate heat. After the heating element 53 heats the reaction tube 204, the heat can be conducted through the heat-conducting block 54 to the heat-conducting pipe 572, and then through the heat-conducting pipe 572 to the heat sink 571 to achieve rapid cooling. The heat sink 571 and the heat-conducting block 54 are spaced apart in the housing 51, which saves space and allows the heat to dissipate quickly during the conduction process, thus improving the cooling rate.

[0116] Furthermore, the heat sink 571 includes multiple spaced heat dissipation fins 5711, and heat pipes 572 pass through the multiple heat dissipation fins 5711 respectively. The heat pipes 572 have high heat transfer efficiency, and the multiple heat dissipation fins 5711 increase the heat dissipation area, significantly improving the cooling rate. In addition, the cooling fan 573 is located between the heat conduction block 54 and the heat sink 571 and is used to blow air towards the heat sink 571, so that the heat on the heat dissipation fins 5711 can be quickly dissipated, further accelerating the cooling rate. In addition, the heat conduction block 54 and the heat sink 571 are located on both sides of the cooling fan 573. The heat conduction pipe 572 extends from the heat conduction block 54 towards the heat sink 571 and bypasses the cooling fan 573. The installation position of the cooling fan 573 increases the length of the heat conduction pipe 572, thereby increasing the distance between the heating element 53 and the heat sink 571, so that the heat can be gradually dissipated during the conduction process, improving the cooling effect.

[0117] In this embodiment of the invention, the rotary drive mechanism 30 includes a rotary drive member 31 and a rotary locking pin 32. The rotary drive member 31 is disposed on the lower side of the mounting base 22, and the mounting base 22 is provided with a mounting hole 222 for the rotary locking pin 32 to pass through. One end of the rotary locking pin 32 is drivenly connected to the rotary drive member 31, and the other end of the rotary locking pin 32 is formed with a locking protrusion 321. When the sliding seat 61 slides to the pre-processing position, the locking protrusion 321 engages with the locking groove 2011 of the rotary valve 201.

[0118] As shown in Figures 13 and 14, the rotary drive 31 is located on the lower side of the mounting base 22, and the rotary locking pin 32 passes through the mounting hole 222. The lower end of the rotary locking pin 32 is driven to connect with the rotary drive 31 so that the rotary drive 31 can drive the rotary locking pin 32 to rotate. The upper end of the rotary locking pin 32 has a locking protrusion 321 that can extend into the locking groove 2011. The push door 62 pushes and pulls the sliding seat 61 to slide to the pre-processing position so that the rotary drive 31 is driven to connect with the rotary valve 201 through the rotary locking pin 32. The rotary drive 31 drives the rotary locking pin 32 to rotate so that... The snap-fit ​​protrusion 321 drives the rotary valve 201 to rotate through the snap-fit ​​groove 2011, thereby enabling the pipetting orifice 202 to connect with any one of the liquid storage chambers 203 through the pipetting channel 2012, realizing sample extraction, pipetting and mixing, with high structural integration; in addition, the size of the snap-fit ​​protrusion 321 is gradually reduced along the radial direction of the rotating snap-fit ​​post 32, and the size of the snap-fit ​​groove 2011 matches the size of the snap-fit ​​protrusion 321 to effectively prevent the sample detection box 200 from being placed in reverse, ensuring that the reaction tube 204 can be inserted from the insertion port 511 into the insertion gap 541, with a reasonable structural design.

[0119] In this embodiment of the invention, the sample detection module 10 further includes a magnetic attraction mechanism 70, which includes a second lifting drive component 71 and a magnetic attraction block 72. The second lifting drive component 71 is mounted on the mounting base 22 and is drivenly connected to the magnetic attraction block 72. The mounting base 22 has a through hole 223 for the magnetic attraction block 72 to pass through. As shown in Figures 10 and 12, the second lifting drive component 71 is used to drive the magnetic attraction block 72 to rise and fall. The magnetic attraction block 72 can pass through the through hole 223 on the mounting base 22 and fit against the sample detection box 200 to perform magnetic attraction processing on the sample in the sample detection box 200. The magnetic attraction mechanism 70 is integrated and mounted on the mounting base 22, saving space and eliminating the need for additional instruments for magnetic attraction processing, simplifying the sample extraction process and improving detection efficiency.

[0120] Furthermore, as shown in Figures 5, 11, and 12, the sliding plate 611 has a clearance hole 6112. When the sliding plate 611 slides above the mounting base 22, the clearance hole 6112 communicates with the through hole 223 so that the magnetic block 72 can pass through the clearance hole 6112 and the through hole 223 to fit against the sample detection box 200. In addition, the magnetic attraction mechanism 70 also includes a mounting bracket 73 and an adapter block 74. The mounting bracket 73 is disposed on the mounting base 22, and the second lifting drive member 71 can be a lead screw motor as in the prior art. The second lifting drive member 71 is mounted on the mounting bracket 73. The adapter block 74 is sleeved on the drive screw of the second lifting drive component 71 and threadedly connected to the drive screw. The magnetic block 72 is disposed on the adapter block 74 so that the second lifting drive component 71 can drive the magnetic block 72 to rise and fall through the adapter block 74, thereby facilitating the magnetic attraction of the sample in the sample detection box 200. The mounting base 22 is provided with a second guide groove 224 for the magnetic block 72 to extend into. The magnetic block 72 can slide up and down along the second guide groove 224. The second guide groove 224 plays the role of guiding the magnetic block 72 to rise and fall, improving the smoothness of the magnetic block 72's rise and fall.

[0121] Furthermore, the adapter block 74 is provided with a third baffle 741, and the side plate 23 is provided with a third sensor 233 and a fourth sensor 234 for detecting the position information of the third baffle 741. The third sensor 233 and the fourth sensor 234 are arranged at intervals in the vertical direction, and the third sensor 233 is located above the fourth sensor 234. When the second lifting drive 71 drives the magnetic block 72 to descend to the initial position, the fourth sensor 234 can detect the position information of the third baffle 741, and then determine the position of the magnetic block 72 below the sliding plate 611 based on the detection result of the fourth sensor 234, so that the sliding plate 611 can move away from the sliding plate 611. The upright plate 21 slides in a direction to place the sample detection box 200, effectively preventing interference between the magnetic block 72 and the sliding plate 611; when the second lifting drive 71 drives the magnetic block 72 to rise to the magnetic position, the third sensor 233 can detect the position information of the third baffle 741, and then determine the magnetic block 72 to rise to fit with the sample detection box 200 based on the detection result of the third sensor 233, so that the magnetic block 72 can perform magnetic attraction processing on the sample; in addition, the first sensor 231, the second sensor 232, the third sensor 233 and the third sensor 233 can all adopt photoelectric switches in the prior art, which are sensitive and reliable.

[0122] In this embodiment of the invention, the sample detection module 10 further includes a heating assembly 80, which includes a connecting bracket 81 and a heating block 82. The connecting bracket 81 is disposed on the frame 20, and the heating block 82 is disposed on the connecting bracket 81 and is used to fit against the sample detection box 200. The connecting bracket 81 is disposed on the side plate 23 and extends above the mounting base 22. The heating block 82 is disposed on the connecting bracket 81 and can fit against the sample detection box 200 to heat the sample inside the sample detection box 200. The structure has high integration and improves space utilization.

[0123] Further, as shown in Figures 2 to 6, the heating assembly 80 also includes a heat insulation block 83 and an elastic sheet 84. The heat insulation block 83 is disposed on the connecting bracket 81, and the heating block 82 is disposed on the side of the heat insulation block 83 facing away from the upright plate 21. The heat insulation block 83 is used to isolate the heat generated by the heating block 82 and prevent the heat from being conducted to the upright plate 21, thereby improving the heating efficiency. The elastic sheet 84 is L-shaped. One end of the elastic sheet 84 is connected to one of the surrounding plates 25, and the other end of the elastic sheet 84 is connected to the side of the heat insulation block 83 facing the upright plate 21. A pressing block 6221 is provided on the side of the door panel 622 facing the upright plate 21. The pressing block 6221 is used to abut against the sample detection box 200 so that the pressing block 6221 can cooperate with the elastic sheet 84 to press the heating block 82 tightly and adhere it to the sample detection box 200, thereby further improving the heating rate.

[0124] In this embodiment of the invention, as shown in FIG1, the sample detection device further includes a housing 90, and the number of sample detection modules 10 is set to multiple, with multiple sample detection modules 10 arranged sequentially inside the housing 90. The housing 90 is provided with placement openings 91 for placing sample detection boxes 200, and the number of placement openings 91 is consistent with the number of sample detection modules 10 and is set one-to-one. Specifically, the sample detection equipment is suitable for processing and detecting samples within multiple sample detection boxes 200. Multiple sample detection modules 10 are housed within the casing 90, arranged sequentially in a left-right direction. Each sample detection module 10 has a placement opening 91 on the casing 90, allowing the sample detection box 200 to be placed onto the sliding seat 61 from the placement opening 91. Each sample detection module 10 can automatically detect the samples within the sample detection box 200, and each module does not interfere with the others, significantly improving detection efficiency and space utilization. This achieves fully automated sample detection, effectively preventing sample contamination caused by contact with the environment during detection. Multiple sample detection modules 10 can simultaneously detect multiple samples, resulting in high detection efficiency. Each sample detection module 10 has a compact structure, high functional integration, and small footprint, improving space utilization. Furthermore, multiple sample detection modules 10 can achieve multi-throughput sample detection within limited space, further enhancing detection efficiency.

[0125] In the description of this invention, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0126] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0127] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0128] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A sample testing device, characterized in that, The sample detection device includes a sample detection module (10), which includes: a frame (20) including a stand (21) and a mounting base (22), the mounting base (22) being disposed on one side of the stand (21) and used to support the sample detection box (200); and a rotary drive mechanism (30) disposed on the lower side of the mounting base (22) and used to drive the rotary valve (201) of the sample detection box (200) to rotate, so that the pipetting orifice on the rotary valve (201) ( 202) can communicate with any of the liquid storage chambers (203) of the sample detection box (200); the lifting mechanism (40) includes a first lifting drive (41), a lifting block (42) and a pickup rod (43), the pickup rod (43) is disposed on the lifting block (42), the first lifting drive (41) is used to drive the lifting block (42) to lift and lower, so that the lifting block (42) drives the pickup rod (43) to pick up the pipette plunger in the pipette hole (202) and perform pipetting.

2. The sample detection device according to claim 1, characterized in that, The sample detection module (10) further includes a push assembly (60), which includes a sliding seat (61) and a push chamber door (62). The sliding seat (61) is slidably disposed on the mounting base (22) and is used for placing the sample detection box (200). The lower end of the push chamber door (62) is rotatably disposed on the mounting base (22). The push chamber door (62) is connected to the sliding seat (61) and is used to push and pull the sliding seat (61) from the loading position to the pretreatment position. When the sliding seat (61) is slid to the pretreatment position, the rotary drive mechanism (30) is driven to connect with the rotary valve (201), and the pickup rod (43) is set corresponding to the pipetting hole (202).

3. The sample detection device according to claim 2, characterized in that, The lifting mechanism (40) also includes a lifting door buckle plate (44), which is disposed on the lifting block (42) and has a door buckle (441). The upper end of the push door (62) is provided with a connecting buckle (621). When the sliding seat (61) slides to the pre-processing position, the door buckle (441) is used to engage with the connecting buckle (621).

4. The sample detection device according to claim 2, characterized in that, The sliding seat (61) includes a sliding plate (611) and a transition plate (612). The sliding plate (611) is slidably disposed on the mounting base (22) and is used for placing the sample detection box (200). The transition plate (612) is connected to the sliding plate (611) and is bent downward from the sliding plate (611). The push chamber door (62) includes a door panel (622) and a connecting plate (623) disposed at the lower end of the door panel (622). The connecting plate (623) is rotatably disposed on the mounting base (22), and a connecting groove (6231) is formed on the connecting plate (623) for the transition plate (612) to extend into.

5. The sample detection device according to claim 4, characterized in that, The mounting base (22) is provided with a mounting post (221), and the connecting plate (623) is provided with a mounting sleeve (6232). The mounting sleeve (6232) is rotatably fitted onto the mounting post (221), and a torsion spring (6233) is fitted onto the mounting sleeve (6232). The two torsion arms of the torsion spring (6233) are respectively connected to the mounting base (22) and the door panel (622); and / or, a pressing block (6221) is provided on the side of the door panel (622) facing the upright plate (21), and the pressing block (6221) is used to abut against the sample detection box (200).

6. The sample detection device according to claim 2, characterized in that, The sample detection module (10) further includes a detection device (50), which includes a housing (51), a temperature control mechanism, and a detection mechanism (52) disposed within the housing (51) for detecting the reaction tube (204) of the sample detection box (200). The housing (51) is disposed on the side of the upright plate (21) facing away from the mounting base (22) and has an insertion port (511). The temperature control mechanism includes a heating element (53) and spaced elements. Two heat-conducting blocks (54) are located inside the housing (51), and an insertion gap (541) communicating with the socket (511) is formed between the two heat-conducting blocks (54). Each heat-conducting block (54) is provided with a heating element (53) on the side facing the insertion gap (541). When the sliding seat (61) slides to the pretreatment position, the reaction tube (204) passes through the socket (511) and extends into the insertion gap (541).

7. The sample detection device according to claim 6, characterized in that, The heat-conducting block (54) has a guide wall (542) formed on the side facing the insertion gap (541). The guide wall (542) is inclined from bottom to top towards the insertion gap (541). The temperature control mechanism also includes a pushing component (55) and a resetting component (56). The pushing component (55) includes a push block (551) extending into the insertion gap (541). The lifting mechanism (40) also includes a lifting push-pull plate (45) disposed on the lifting block (42). The lifting push-pull plate (45) is connected to the push block (551) and is used to drive the push block (551) to slide along the extension direction of the guide wall (542), so that the push block (551) pushes the two heat-conducting blocks (54) to move in opposite directions. The resetting component (56) includes a push block (551) disposed on the side facing the insertion gap (541). A first spring (561) is located between the housing (51) and the heat-conducting block (54), with its two ends respectively abutting against the housing (51) and the heat-conducting block (54); and / or, the temperature control mechanism further includes a heat dissipation assembly (57), which includes a heat sink (571), a heat-conducting pipe (572), and a heat dissipation fan (573). The heat sink (571) is located inside the housing (51) and spaced apart from the heat-conducting block (54). The two ends of the heat-conducting pipe (572) are respectively embedded in the heat-conducting block (54) and the heat sink (571). The heat dissipation fan (573) is located on one side of the heat sink (571) and between the heat-conducting block (54) and the heat sink (571).

8. The sample detection device according to claim 2, characterized in that, The rotary drive mechanism (30) includes a rotary drive component (31) and a rotary locking pin (32). The rotary drive component (31) is located on the lower side of the mounting base (22), and the mounting base (22) has a mounting hole (222) through which the rotary locking pin (32) passes. One end of the rotary locking pin (32) is driven to connect with the rotary drive component (31), and the other end of the rotary locking pin (32) has a locking protrusion (321). When the sliding seat (61) slides to the pre-processing position, the locking protrusion (321) engages with the slot (2011) of the rotary valve (201).

9. The sample detection device according to any one of claims 1 to 8, characterized in that, The sample detection module (10) further includes a magnetic suction mechanism (70), which includes a second lifting drive (71) and a magnetic block (72). The second lifting drive (71) is disposed on the mounting base (22) and drivenly connected to the magnetic block (72). The mounting base (22) has a through hole (223) for the magnetic block (72) to pass through.

10. The sample detection device according to any one of claims 1 to 8, characterized in that, The sample detection device also includes a cover (90), and the number of sample detection modules (10) is set to multiple. The multiple sample detection modules (10) are arranged sequentially inside the cover (90), and the cover (90) has a placement port (91) for the sample detection box (200) to be placed in. The number of placement ports (91) is consistent with the number of sample detection modules (10) and is set one-to-one.

Images