Liquid sample processing device

Abstract

The invention relates to the technical field of sample treatment devices, and discloses a liquid sample treatment device, which comprises a bearing structure for bearing a sample bottle containing liquid; the sample injection pin is mounted on the driving mechanism, and the driving mechanism is used for driving the sample injection pin to move; the control unit is communicated with the liquid storage structure; the driving pump structure is communicated with the sample injection inserting needle, the driving pump structure can drive liquid in the sample bottle to be pumped into the sample injection inserting needle, the driving pump structure can drive the liquid in the sample injection inserting needle to flow into the liquid storage structure, the driving pump structure is further communicated with the first connector, and the driving pump structure can drive liquid in the liquid storage structure to flow out from the sample outlet. By arranging the liquid sample treatment device, the treatment efficiency of the liquid sample can be improved, the liquid sample treatment device can meet the development requirements of automation and intelligentization, the risk that the liquid sample is polluted can be reduced, and the pollution rate of the liquid sample can be reduced when the liquid sample with a low boiling point is treated. The risk that the sample concentration is changed due to liquid volatilization is avoided.

Description

Liquid sample processing device Technical Field

[0001] This invention relates to the field of sample processing apparatus, and in particular to a liquid sample processing apparatus. Background Technology

[0002] In current flow chemistry experiments, the injection of liquid samples into the reaction system still relies on syringe pumps. This requires manual pre-preparation of the liquid sample and determination of the required volume, which is inefficient and hinders automation and intelligentization. Furthermore, for some low-boiling-point liquid samples, some evaporation occurs during transfer, altering the sample concentration. Summary of the Invention

[0003] The present invention aims to at least solve one of the technical problems existing in the prior art. Therefore, one object of the present invention is to provide a liquid sample processing device that improves the processing efficiency of liquid samples, makes the liquid sample processing device meet the development needs of automation and intelligence, reduces the risk of liquid sample contamination, and also reduces the risk of changes in sample concentration due to liquid evaporation when processing low-boiling-point liquid samples.

[0004] According to an embodiment of the present invention, a liquid sample processing apparatus includes: a support structure for supporting a sample vial containing liquid; an injection needle and a driving mechanism, the injection needle being mounted on the driving mechanism and the driving mechanism driving the injection needle to move; a control unit and a liquid storage structure, the control unit and the liquid storage structure being connected, the control unit having an inlet, an outlet and a first interface, and the control unit having a first connected state and a second connected state; a driving pump structure, the driving pump structure being connected to the injection needle, the driving pump structure being configured to drive the liquid in the sample vial into the injection needle when the driving mechanism drives the injection needle to be inserted into the sample vial, and the driving pump structure being further configured to drive the liquid in the injection needle to flow into the liquid storage structure when the driving mechanism drives the injection needle to be inserted into the inlet and the control unit is in the first connected state, the driving pump structure being further connected to the first interface, and the driving pump structure being further configured to drive the liquid in the liquid storage structure to flow out from the outlet when the control unit is in the second connected state.

[0005] The liquid sample processing apparatus according to embodiments of the present invention, by setting up the liquid sample processing apparatus, is beneficial to improving the processing efficiency of liquid samples, is beneficial to making the liquid sample processing apparatus meet the development needs of automation and intelligence, is beneficial to reducing the risk of liquid sample contamination, and is also beneficial to reducing the risk of sample concentration changes due to liquid evaporation when processing low-boiling-point liquid samples.

[0006] In some examples of the present invention, when the control unit is in a first connected state, the liquid storage structure is connected to the sample inlet; when the control unit is in a second connected state, the liquid storage structure is connected to the sample outlet and the first interface.

[0007] In some examples of the present invention, the control unit also has a second interface and a third interface, and the liquid storage structure is connected to the second interface and the third interface. When the control unit is in a first connected state, the second interface is connected to the sample inlet and the liquid storage structure. When the control unit is in a second connected state, the second interface is connected to the first interface and the liquid storage structure, and the third interface is connected to the liquid storage structure and the sample outlet.

[0008] In some examples of the present invention, the control unit also has a waste liquid outlet, and when the control unit is in a first connected state, the liquid storage structure connects the sample inlet and the waste liquid outlet.

[0009] In some examples of the present invention, the drive pump structure includes: a first drive pump, which is connected to the injection needle and is configured to drive liquid in the sample vial into the injection needle, and is also configured to drive liquid in the injection needle into the storage structure; and a second drive pump, which is connected to the first interface and is configured to drive liquid in the storage structure to flow out from the sample outlet.

[0010] In some examples of the present invention, the support structure and the control unit are arranged along a first direction, and the injection port is located above the control unit. The driving mechanism is used to drive the injection needle to move along the first direction, the second direction and the vertical direction, which are perpendicular to each other.

[0011] In some examples of the present invention, the driving mechanism includes: a first driving part, a second driving part, and a third driving part, wherein the second driving part is mounted on the first driving part, the third driving part is mounted on the second driving part, and the injection needle is mounted on the third driving part. The first driving part is used to drive the second driving part, the third driving part, and the injection needle to move synchronously along a first direction, the second driving part is used to drive the third driving part and the injection needle to move synchronously along a second direction, and the third driving part is used to drive the injection needle to move along a vertical direction.

[0012] In some examples of the present invention, the injection needle includes: a needle section and a mixing section connected together, wherein a mixing channel is formed in the mixing section, and a liquid channel communicating with the mixing channel is formed in the needle section, wherein the cross-sectional area of ​​the mixing channel is larger than the cross-sectional area of ​​the liquid channel.

[0013] In some examples of the present invention, the drive mechanism has a mounting bracket, the injection pin is mounted on the mounting bracket, and the injection pin is movable relative to the mounting bracket in the axial direction of the injection pin.

[0014] In some examples of the present invention, the drive mechanism further includes an elastic reset member, a mounting bracket forming a mounting cavity, a sample injection needle passing through the mounting cavity, a limiting boss forming on the outer peripheral wall of the sample injection needle within the mounting cavity, a limiting surface forming within the mounting cavity that is opposite to and spaced apart from the limiting boss along the axial direction of the sample injection needle, the limiting surface being located on the side of the limiting boss away from the insertion end of the sample injection needle, the elastic reset member being located within the mounting cavity and between the limiting boss and the limiting surface, and the elastic reset member contacting both the limiting boss and the limiting surface.

[0015] Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0016] The above and / or additional aspects and advantages of the present invention will become apparent and readily understood from the description of the embodiments in conjunction with the following drawings, in which: FIG1 is a structural schematic diagram of a liquid sample processing apparatus according to an embodiment of the present invention; FIG2 is a structural schematic diagram of a liquid sample processing apparatus according to an embodiment of the present invention from another angle; FIG3 is an assembly schematic diagram of a control unit and a liquid storage structure according to an embodiment of the present invention; FIG4 is a structural schematic diagram of a drive pump structure according to an embodiment of the present invention; FIG5 is a structural schematic diagram of a second mounting structure according to an embodiment of the present invention; FIG6 is a structural schematic diagram of a third mounting structure according to an embodiment of the present invention; FIG7 is an assembly schematic diagram of a support structure and a sample vial according to an embodiment of the present invention; FIG8 is a structural schematic diagram of a first mounting structure according to an embodiment of the present invention; FIG9 is a cross-sectional view of a sample inlet pin and a mounting bracket according to an embodiment of the present invention.

[0017] Reference numerals: Liquid sample processing device 100; device base 110; supporting structure 200; first mounting groove 210; placement groove 220; sample bottle 300; sample insertion needle 400; needle section 410; liquid flow channel 411; Teflon tube 412; connector 413; mixing section 420; mixing flow channel 421; limiting boss 430; insertion end 440; drive mechanism 500; first drive part 510; first drive motor 511; first limiting structure 512; first limiting plate 513; first base plate 514; first moving part Part 515; First threaded screw 516; First mounting space 517; Second drive unit 520; Second drive motor 521; Second limiting structure 522; Second limiting plate 523; Second mounting plate 524; Second moving part 525; Second threaded screw 526; Second mounting space 527; Third drive unit 530; Third drive motor 531; Third limiting structure 532; Third limiting plate 533; Third mounting plate 534; Third moving part 535; Third threaded screw 536; Third mounting space 537; Mounting bracket 54 0; Elastic reset component 550; Mounting cavity 560; Limiting surface 561; First contact body 570; First contact plate 571; Second contact plate 572; Second contact body 580; Control unit 600; Sample inlet 610; Sample outlet 620; First interface 630; Second interface 640; Third interface 650; Waste liquid outlet 660; Liquid storage structure 700; Drive pump structure 800; First drive pump 810; First drive pump interface 811; Second drive pump 820; Second drive pump interface 821; First mounting structure 9 10; First main body 911; Second main body 912; First bottom wall 913; Spacing structure 914; Mounting boss 915; Second mounting groove 916; Second mounting structure 920; First mounting part 921; Second mounting part 922; First plate 923; Second plate 924; Third plate 925; Fourth plate 926; Third mounting groove 927; Third mounting structure 930; Third mounting part 931; Fourth mounting part 932; Sixth plate 933; Seventh plate 934; Eighth plate 935; First mounting plate 940. Detailed Implementation

[0018] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0019] The liquid sample processing apparatus 100 according to an embodiment of the present invention will now be described with reference to Figures 1-9.

[0020] As shown in Figure 1, a liquid sample processing device 100 according to an embodiment of the present invention includes: a support structure 200 for supporting a sample bottle 300 containing liquid; an injection needle 400 and a driving mechanism 500, the injection needle 400 being mounted on the driving mechanism 500 and the driving mechanism 500 for driving the injection needle 400 to move; a control unit 600 and a liquid storage structure 700, the control unit 600 and the liquid storage structure 700 being connected, the control unit 600 having an inlet 610, an outlet 620 and a first interface 630, and the control unit 600 having a first connected state and a second connected state; and a driving pump structure 800. The pump structure 800 is connected to the injection needle 400. The pump structure 800 is configured to drive the liquid in the sample vial 300 into the injection needle 400 when the injection needle 400 is inserted into the sample vial 300 by the driving mechanism 500. The pump structure 800 is also configured to drive the liquid in the injection needle 400 into the storage structure 700 when the injection needle 400 is inserted into the injection port 610 by the driving mechanism 500 and the control unit 600 is in the first connected state. The pump structure 800 is also connected to the first interface 630. The pump structure 800 is also configured to drive the liquid in the storage structure 700 to flow out from the sample outlet 620 when the control unit 600 is in the second connected state.

[0021] As shown in Figure 1, the liquid sample processing device 100 may include a device base 110. As shown in Figure 1, the first direction is defined as the X direction, the second direction as the Y direction, and the vertical direction as the Z direction. As shown in Figure 1, two support structures 200 may be provided, and the two support structures 200 may be arranged sequentially along the second direction. As shown in Figures 1 and 7, the support structure 200 may be provided with multiple placement slots 220, and the open ends of the multiple placement slots 220 may be positioned away from the device base 110 along the vertical direction. Sample bottles 300 can be placed in the placement slots 220 so that the support structure 200 can stably support the sample bottles 300. The support structure 200 may be made of materials such as polyethylene tetroxide or polypropylene.

[0022] As shown in Figures 1 and 8, the liquid sample processing device 100 may include a first mounting structure 910, which is located above the device base 110. The first mounting structure 910 may be integrally constructed with the device base 110, or it may be fixed to the device base 110 by fasteners such as bolts or clips. As shown in Figure 8, the first mounting structure 910 may include a first bottom wall 913 and a first side wall. The first bottom wall 913 is fixedly connected to the device base 110, and the first side wall extends along the circumferential edge of the first bottom wall 913, thereby defining a second mounting groove 916. The bearing structure 200 is assembled into the second mounting groove 916. The first side wall may include a first body 911 extending in a first direction and a second body 912 extending in a second direction. In the first direction, the second body 912 may face the sample injection needle 400.

[0023] As shown in Figure 8, the first sidewall may include two first bodies 911 and one second body 912. The two first bodies 911 are opposite to each other and spaced apart along a second direction, and the second body 912 is connected between the two first bodies 911. As shown in Figure 8, the first mounting structure 910 may also include a spacer structure 914. Along the second direction, the spacer structure 914 may be located between the two first bodies 911. The spacer structure 914 may extend along the first direction and may be fixed to at least one of the first bodies 911 and the second body 912. The spacer structure 914 is located in the second mounting groove 916 and can divide the second mounting groove 916 into multiple sub-mounting grooves. Each sub-mounting groove is used to install a load-bearing structure 200.

[0024] As shown in Figures 7 and 8, at least a portion of the supporting structure 200 can be disposed within a corresponding sub-mounting groove. Vertically, the supporting structure 200 can have at least one first mounting groove 210 opening towards the first mounting structure 910. The first mounting structure 910 can be provided with mounting bosses 915, each sub-mounting groove having a mounting boss 915. The mounting bosses 915 can be fixed to at least one of the first bottom wall 913, the spacer structure 914, and the first side wall. The mounting bosses 915 can be assembled within the first mounting groove 210 to position the supporting structure 200 within the first mounting structure 910. The first body 911, the second body 912, the first bottom wall 913, the spacer structure 914, and the mounting bosses 915 can be integrally formed.

[0025] As one embodiment, the drive mechanism 500 has a mounting bracket 540, on which the sample insertion needle 400 is mounted. Exemplarily, the liquid storage structure 700 can be configured as a quantitative loop. The liquid sample processing apparatus 100 of this application can replace the liquid storage structure 700 with different volumes. The control unit 600 can be connected to the liquid storage structure 700 via a connecting pipe.

[0026] As shown in Figures 1 and 5, the liquid sample processing device 100 may include a second mounting structure 920. The second mounting structure 920 is located above the device base 110 and is fixed to the device base 110. The second mounting structure 920 can be constructed as an integral unit with the device base 110, or it can be fixed to the device base 110 by fasteners such as bolts or clips. As shown in Figure 5, the second mounting structure 920 may include a first mounting part 921 and a second mounting part 922. The first mounting part 921 may include a first plate 923 and a second plate 924. The first plate 923 can be fixedly connected to the device base 110. In the vertical direction, the second plate 924 can be located above the first plate 923 and can be fixedly connected to the first plate 923. The second plate 924 can be perpendicular to the first plate 923.

[0027] As shown in Figure 5, the second mounting portion 922 may include a fourth plate 926, which may be located above the second plate 924 and fixedly connected to the second plate 924. The fourth plate 926 may be arranged parallel to the first plate 923. As shown in Figure 5, the second mounting portion 922 may also include two third plates 925. Along the second direction, the two third plates 925 may be fixed to both ends of the fourth plate 926, and the two third plates 925 may be arranged parallel to each other. As shown in Figure 5, the two third plates 925 and the fourth plate 926 may together define a third mounting groove 927. At least a portion of the control unit 600 may be assembled within the third mounting groove 927 so that the second mounting structure 920 can stably support the control unit 600.

[0028] As an example, the drive mechanism 500, control unit 600 and drive pump structure 800 of this application can all communicate with the user's terminal device (such as a computer). The user can set the position of the sample bottle 300 to be sampled, the amount of sample to be taken and the order of sampling in the terminal device, and the liquid sample processing device 100 can automatically complete the operation.

[0029] For example, when performing a flow chemistry experiment using the liquid sample processing device 100 of the present invention, the drive mechanism 500 can drive the injection needle 400 to insert into the sample vial 300. At this time, the drive pump structure 800 can draw the liquid sample in the sample vial 300 into the injection needle 400. After sampling, the drive mechanism 500 can drive the injection needle 400 to insert into the injection port 610, and the control unit 600 can automatically switch to the first connected state. The drive pump structure 800 can drive the liquid in the injection needle 400 to flow into the storage structure 700. When the sample needs to enter the reaction system, the control unit 600 can automatically switch to the second connected state. The drive pump structure 800 can drive the liquid sample in the storage structure 700 to flow out of the storage structure 700 from the outlet 620, so that the liquid sample flows into the subsequent reaction system. The entire process does not require manual sampling, injection, or pipetting, which helps to improve the overall efficiency of liquid sample processing and makes the liquid sample processing device 100 meet the development needs of automation and intelligence.

[0030] The aforementioned flow chemistry is a technology that uses continuously flowing pipes or microreactors to carry out chemical reactions, replacing traditional batch reactors. It can improve reaction efficiency, safety, and process control precision, and is widely used in pharmaceuticals, fine chemicals, and other fields.

[0031] Meanwhile, when using the liquid sample processing device 100 of the present invention to conduct flow chemistry experiments, the liquid sample in the sample bottle 300 flows into the liquid storage structure 700 through the injection needle 400 and then flows out of the liquid storage structure 700 from the sample outlet 620. The liquid sample in the sample bottle 300 is directly extracted by the injection needle 400, and the entire experimental process is carried out within the internal structure of the liquid sample processing device 100. The liquid sample does not need to be exposed to the external environment, which helps to reduce the risk of liquid sample contamination and also helps to reduce the risk of liquid sample concentration changes due to liquid evaporation when processing low-boiling-point liquid samples.

[0032] The liquid sample processing apparatus 100 according to the embodiments of the present invention can improve the processing efficiency of liquid samples, make the liquid sample processing apparatus 100 meet the development needs of automation and intelligence, reduce the risk of liquid sample contamination, and reduce the risk of sample concentration change due to liquid evaporation when processing low boiling point liquid samples.

[0033] In some examples of embodiments of the present invention, as shown in FIG3, when the control unit 600 is in the first connected state, the liquid storage structure 700 is connected to the sample inlet 610; when the control unit 600 is in the second connected state, the liquid storage structure 700 is connected to the sample outlet 620 and the first interface 630.

[0034] When the control unit 600 is in the first connected state, the liquid storage structure 700 is connected to the sample inlet 610. At this time, the drive mechanism 500 can drive the sample injection needle 400 to insert into the sample inlet 610, and the drive pump structure 800 can drive the liquid in the sample injection needle 400 to flow into the liquid storage structure 700, thereby completing the automated connection of liquid sample sampling and temporary storage without manual transfer of liquid samples. When the control unit 600 switches to the second connected state, the liquid storage structure 700 is connected to the sample outlet 620 and the first interface 630. The drive pump structure 800 can drive the liquid in the liquid storage structure 700 to flow out from the sample outlet 620, completing the liquid sample transfer operation. The entire process does not require manual intervention for liquid transfer or container switching, which is conducive to further improving the processing efficiency of liquid samples and also helps the liquid sample processing device 100 to meet the development needs of automation and intelligence.

[0035] When the control unit 600 is in the first connected state, the liquid storage structure 700 is connected to the sample inlet 610, and the liquid can only flow into the liquid storage structure 700 from the sample inlet 610. When the control unit 600 is in the second connected state, the liquid storage structure 700 is connected to the sample outlet 620 and the first interface 630, and the liquid can only flow from the liquid storage structure 700 to the sample outlet 620. This is beneficial to make the sampling and sample outlet channels of the liquid sample processing device 100 completely independent.

[0036] The liquid in the liquid sample processing device 100 always flows in a closed flow path composed of the sample injection needle 400, the control unit 600, and the liquid storage structure 700, without any exposure to air. This helps to further reduce the risk of liquid sample contamination and further reduce the risk of sample concentration changes due to liquid evaporation when processing low-boiling-point liquid samples.

[0037] Meanwhile, the present invention realizes the functions of liquid sample temporary storage and sample dispensing only through the control unit 600 and the liquid storage structure 700, without the need for additional switching valves or redundant pipelines. This helps to reduce the number of parts in the liquid sample processing device 100, makes the liquid sample processing device 100 more compact, and also helps to reduce the manufacturing cost of the liquid sample processing device 100.

[0038] In some examples of embodiments of the present invention, as shown in FIG3, the control unit 600 further has a second interface 640 and a third interface 650. The liquid storage structure 700 is connected to the second interface 640 and the third interface 650. When the control unit 600 is in a first connected state, the second interface 640 is connected to the sample inlet 610 and the liquid storage structure 700. When the control unit 600 is in a second connected state, the second interface 640 is connected to the first interface 630 and the liquid storage structure 700, and the third interface 650 is connected to the liquid storage structure 700 and the sample outlet 620.

[0039] The liquid sample processing device 100 can automatically switch the connection state of the control unit 600. In the first state, the second interface 640 connects the sample inlet 610 and the liquid storage structure 700; in the second state, it connects the first interface 630 and the liquid storage structure 700; and in the third state, the third interface 650 connects the liquid storage structure 700 and the sample outlet 620. This design facilitates controllability of the liquid flow path and allows the liquid sample processing device 100 to meet the demands of automation and intelligence. The control unit 600 can seamlessly switch between the first and second states simply by switching interfaces, without interrupting the process or adjusting the pipeline, further improving the processing efficiency of liquid samples. It should be noted that the control unit 600 may include a two-position six-way valve, with multiple valve interfaces including the sample inlet 610, sample outlet 620, first interface 630, second interface 640, third interface 650, and waste outlet 660.

[0040] In some examples of embodiments of the present invention, as shown in FIG3, the control unit 600 also has a waste liquid outlet 660. When the control unit 600 is in the first connected state, the liquid storage structure 700 connects the sample inlet 610 and the waste liquid outlet 660.

[0041] When the control unit 600 is in the first connected state and the pipeline needs to be cleaned, the liquid storage structure 700 connects the sample inlet 610 and the waste liquid outlet 660. The cleaning solution can flow into the liquid storage structure 700 through the sample inlet 610, and then flow through the liquid storage structure 700 and be discharged from the waste liquid outlet 660. This is beneficial for cleaning the interface of the control unit 600 and the liquid storage structure 700 and for discharging waste liquid, and helps to reduce the risk of cross-contamination between different samples.

[0042] Meanwhile, by providing a waste liquid outlet 660, this invention allows for the cleaning and waste liquid treatment of the internal structure of the liquid storage structure 700 without disassembling the liquid sample processing device 100. This facilitates the integration of the liquid sample processing device 100 with automation design principles and enhances its ease of use. The cleaning solution can be directly discharged through the waste liquid outlet 660, reducing the risk of contamination of subsequent liquid samples flowing into the liquid storage structure 700 by the cleaning solution, thereby helping to maintain the stability of the concentration and composition of the liquid samples within the liquid storage structure 700.

[0043] In some examples of embodiments of the present invention, as shown in Figures 1 and 4, the drive pump structure 800 includes: a first drive pump 810, which is connected to the injection pin 400. The first drive pump 810 is configured to drive the liquid in the sample vial 300 into the injection pin 400, and is also configured to drive the liquid in the injection pin 400 into the liquid storage structure 700; and a second drive pump 820, which is connected to the first interface 630. The second drive pump 820 is configured to drive the liquid in the liquid storage structure 700 to flow out from the sample outlet 620.

[0044] As shown in Figure 4, the first drive pump 810 may be provided with at least one first drive pump interface 811, and the second drive pump 820 may be provided with at least one second drive pump interface 821. The first drive pump interface 811 may be connected to the injection needle 400, and the second drive pump interface 821 may be connected to the first interface 630. The first drive pump 810 can drive the injection needle 400 to draw liquid into the sample vial 300, and the first drive pump 810 can also drive the liquid in the injection needle 400 to flow into the liquid storage structure 700. The second drive pump 820 can also drive the liquid in the liquid storage structure 700 to flow out from the sample outlet 620. The division of labor between the first drive pump 810 and the second drive pump 820 is clear and they do not interfere with each other, which helps to reduce problems such as insufficient power or unstable pressure caused by a single drive pump undertaking multiple steps at the same time.

[0045] In some examples of embodiments of the present invention, as shown in FIG1, the support structure 200 and the control unit 600 are arranged along the first direction, and the sample inlet 610 is located on the upper side of the control unit 600. The driving mechanism 500 is used to drive the sample insertion pin 400 to move along the first direction, the second direction and the vertical direction, which are perpendicular to each other.

[0046] The supporting structure 200 and the control unit 600 are arranged along the first direction, which helps to make the overall structure of the liquid sample processing device 100 more regular. Meanwhile, the sample inlet 610 is located above the control unit 600, which helps to align the sample inlet 610 with the vertical movement direction of the sample insertion pin 400 driven by the drive mechanism 500, facilitating the insertion of the sample insertion pin 400 into the sample inlet 610. The drive mechanism 500 can drive the sample insertion pin 400 to align with each sample bottle 300 on the supporting structure 200, and can also drive the sample insertion pin 400 to align with the sample inlet 610 located above the control unit 600, completing sampling and injection operations without additional adjustment of the liquid sample processing device 100's position.

[0047] In some examples of embodiments of the present invention, as shown in Figures 1 and 2, the driving mechanism 500 includes: a first driving part 510, a second driving part 520, and a third driving part 530. The second driving part 520 is mounted on the first driving part 510, the third driving part 530 is mounted on the second driving part 520, and the injection pin 400 is mounted on the third driving part 530. The first driving part 510 is used to drive the second driving part 520, the third driving part 530, and the injection pin 400 to move synchronously along a first direction. The second driving part 520 is used to drive the third driving part 530 and the injection pin 400 to move synchronously along a second direction. The third driving part 530 is used to drive the injection pin 400 to move along a vertical direction.

[0048] As shown in Figure 1, the first drive unit 510 is mounted on the device base 110. The liquid sample processing device 100 may include a first mounting plate 940. As shown in Figure 2, the first drive unit 510 may include a first drive motor 511, a first limiting structure 512, a first moving part 515, and a first threaded screw 516. The first drive motor 511 may be configured as a stepper motor, and the first limiting structure 512 may include two first limiting plates 513 and a first base plate 514. The first base plate 514 may extend along a first direction and may be fixedly connected to the first mounting plate 940.

[0049] Two first limiting plates 513 can be respectively disposed at both ends of the first base plate 514 along the first direction. The two first limiting plates 513 and the first base plate 514 can define a first installation space 517. In the vertical direction, the first moving part 515 can be located above the first base plate 514, and at least a portion of the first moving part 515 can be disposed within the first installation space 517.

[0050] The first limiting structure 512 can limit the movement distance of the first moving part 515. The first threaded rod 516 can extend along the first direction and can be coaxially arranged with the output shaft of the first drive motor 511. A first threaded hole can be provided in the first moving part 515, which extends through the first moving part 515 along the first direction. The first threaded rod 516 can pass through the first threaded hole. At the same time, the first threaded rod 516 is rotatably arranged on two first limiting plates 513, and the first threaded rod 516 passes through the first limiting plate 513 facing the first drive motor 511.

[0051] As shown in Figure 2, the second driving unit 520 may include a second driving motor 521, a second limiting structure 522, a second moving part 525, and a second threaded screw 526. The second driving motor 521 may be configured as a stepper motor, and the second limiting structure 522 may include two second limiting plates 523 and a second mounting plate 524. The second mounting plate 524 may extend along a second direction.

[0052] Two second limiting plates 523 can be respectively disposed at both ends of the second mounting plate 524 along the second direction. The two second limiting plates 523 and the second mounting plate 524 can define a second mounting space 527. Along the first direction, the second moving part 525 can be located on the side of the second mounting plate 524 facing the sample insertion pin 400, and at least a portion of the second moving part 525 can be located within the second mounting space 527.

[0053] The second limiting structure 522 can limit the movement distance of the second moving part 525. The second threaded rod 526 can extend along the second direction and can be coaxially arranged with the output shaft of the second drive motor 521. A second threaded hole can be provided in the second moving part 525, which extends through the second moving part 525 along the second direction. The second threaded rod 526 can pass through the second threaded hole. At the same time, the second threaded rod 526 is rotatably arranged on two second limiting plates 523. The second threaded rod 526 passes through the second limiting plate 523 facing the second drive motor 521, and the second threaded rod 526 can be rotatably fixed to the second limiting plate 523 facing away from the second drive motor 521.

[0054] As shown in Figure 2, the liquid sample processing device 100 may include a first contact body 570. The first contact body 570 may include a first contact plate 571 and a second contact plate 572, which may be integrally formed. Vertically, the second contact plate 572 may be disposed above the first moving part 515, and the second contact plate 572 may be fixedly connected to the first moving part 515. The second contact plate 572 may be connected to the first contact plate 571, and the first contact plate 571 may be fixed to the side of the second mounting plate 524 opposite to the sample insertion needle 400 along the first direction. Simultaneously, the second contact plate 572 may be perpendicular to the first contact plate 571.

[0055] As shown in Figure 2, the third drive unit 530 may include a third drive motor 531, a third limiting structure 532, a third moving part 535, and a third threaded screw 536. The third drive motor 531 may be configured as a stepper motor, and the third limiting structure 532 may include two third limiting plates 533 and a third mounting plate 534. The third mounting plate 534 may extend in the vertical direction.

[0056] Two third limiting plates 533 can be respectively disposed at both ends of the third mounting plate 534 in a vertical direction. The two third limiting plates 533 and the third mounting plate 534 can define a third mounting space 537. In the first direction, the third moving part 535 can be located on the side of the third mounting plate 534 facing the sample insertion pin 400, and at least a portion of the third moving part 535 can be located within the third mounting space 537.

[0057] The third limiting structure 532 can limit the length of the movement path of the third moving part 535. The third threaded rod 536 can extend vertically and can be coaxially arranged with the output shaft of the third drive motor 531. A third threaded hole can be provided in the third moving part 535, penetrating the third moving part 535 in a vertical direction. The third threaded rod 536 can pass through the third threaded hole. At the same time, the third threaded rod 536 is rotatably mounted on two third limiting plates 533. The third threaded rod 536 can pass through the third limiting plate 533 facing the third drive motor 531, and the second threaded rod 526 can be rotatably fixed to the third limiting plate 533 facing away from the third drive motor 531.

[0058] As shown in Figure 2, the liquid sample processing device 100 may include a second contact body 580. Along the first direction, the second contact body 580 may be disposed between the second moving part 525 and the third mounting plate 534, and the second contact body 580 may be fixedly connected to both the second moving part 525 and the third mounting plate 534.

[0059] As shown in Figures 2 and 6, the liquid sample processing device 100 may include multiple third mounting structures 930. These multiple third mounting structures 930 may be arranged sequentially at intervals along a first direction. Each third mounting structure 930 may include a third mounting portion 931 and a fourth mounting portion 932. All of the multiple third mounting structures 930 may be fixedly connected to the device base 110. As shown in Figure 2, this application uses an example where the liquid sample processing device 100 includes two third mounting structures 930 for illustration. The fourth mounting portion 932 may include a sixth plate 933 fixedly connected to the device base 110, a seventh plate 934 fixedly connected to the third mounting portion 931, and two eighth plates 935.

[0060] Both eighth plates 935 can be fixedly connected to the sixth plate 933 and the seventh plate 934. The sixth plate 933 and the seventh plate 934 can both be constructed as rectangular plates, and both eighth plates 935 can both be constructed as triangular plates, with the hypotenuse of the triangular plate inclined from the seventh plate 934 towards the sixth plate 933 along a first direction. Vertically, the third mounting part 931 can be fixedly connected to the first mounting plate 940, and vertically, the first mounting plate 940 can be located between the third mounting part 931 and the first base plate 514.

[0061] As an example, when the first drive motor 511 of the first drive unit 510 is started, the output shaft of the first drive motor 511 can drive the coaxially arranged first threaded screw 516 to rotate. The first threaded screw 516 passes through the first threaded hole of the first moving part 515. With the first threaded screw 516 threadedly engaged with the first threaded hole, the first moving part 515 can move along the extension direction (i.e., the first direction) of the first base plate 514. The first contact body 570 fixed above the first moving part 515 can move synchronously with the first moving part 515, thereby driving the second contact plate 572 fixedly connected to the first contact body 570 to move synchronously, thereby driving the second drive unit 520, the third drive unit 530 and the sample insertion needle 400 to move synchronously along the first direction.

[0062] When the second drive motor 521 of the second drive unit 520 is started, the output shaft of the second drive motor 521 can drive the coaxial second threaded screw 526 to rotate. The second threaded screw 526 is threadedly engaged with the second threaded hole of the second moving part 525, which can drive the second moving part 525 to move along the extension direction (i.e., the second direction) of the second mounting plate 524. The second moving part 525 can drive the third drive unit 530 and the sample insertion needle 400 to move synchronously along the second direction through the second contact body 580.

[0063] When the third drive motor 531 of the third drive unit 530 is started, the output shaft of the third drive motor 531 drives the coaxial third threaded screw 536 to rotate. The third threaded screw 536 is threadedly engaged with the third threaded hole of the third moving part 535, which can drive the third moving part 535 to move along the extension direction (i.e., the vertical direction) of the third mounting plate 534. In turn, the third moving part 535 can drive the sample insertion needle 400 to move in the vertical direction.

[0064] The drive mechanism 500 composed of the first drive unit 510, the second drive unit 520 and the third drive unit 530 in this invention can be replaced by other three-axis drive structures that can drive the sample injection pin 400 to move along the first direction, the second direction and the vertical direction. Alternatively, the movable range of the sample injection pin 400 along the first direction, the second direction and the vertical direction can be expanded by optimizing the structural design of the first drive unit 510, the second drive unit 520 and the third drive unit 530.

[0065] The first drive unit 510 can drive the injection pin 400 to switch positions between the support structure 200 and the control unit 600 along the first direction. The second drive unit 520 can adjust the position of the injection pin 400 in the second direction so that the injection pin 400 can be adapted to the arrangement of multiple sample bottles 300 and the precise alignment of the injection pin 400 and the injection port 610. The third drive unit 530 can drive the injection pin 400 to move in the vertical direction to realize the action of the injection pin 400 inserting or detaching from the sample bottle 300 and the injection port 610. This is beneficial to enable the injection pin 400 to stop accurately at the preset coordinates, and to enable the liquid sample processing device 100 to adapt to sample bottles 300 or injection ports 610 of different diameters and heights, thereby improving the versatility of the liquid sample processing device 100. Meanwhile, by setting up the drive mechanism 500, the liquid sample processing device 100 can automatically complete the sampling of liquid samples. Compared with traditional manual sampling, it is more conducive to improving the processing efficiency of liquid samples and making the liquid sample processing device 100 more in line with the development needs of automation and intelligence.

[0066] In some examples of embodiments of the present invention, as shown in FIG9, the injection needle 400 includes: a needle section 410 and a mixing section 420 connected together. A mixing channel 421 is formed in the mixing section 420, and a liquid channel 411 communicating with the mixing channel 421 is formed in the needle section 410. The cross-sectional area of ​​the mixing channel 421 is larger than the cross-sectional area of ​​the liquid channel 411.

[0067] As shown in Figure 9, the insertion section 410 may be equipped with a Teflon tube 412 and a connector 413, and the Teflon tube 412 may be connected to the first drive pump 810. As an example, a static mixer may be installed within the mixing channel 421 to enhance the mixing effect of the solute with the solvent or multiple liquid samples.

[0068] The insertion section 410 forms a liquid flow channel 411, and the mixing section 420 forms a mixing flow channel 421, with the cross-sectional area of ​​the mixing flow channel 421 being larger than that of the liquid flow channel 411. When multiple liquid samples sequentially enter the mixing flow channel 421 through the liquid flow channel 411, the liquid flow space increases, forming turbulence. The turbulence intensifies the irregular movement of liquid molecules, allowing different components of the multiple liquids to collide and diffuse fully, which is beneficial for improving the mixing effect of solute and solvent or multiple liquids.

[0069] Meanwhile, the mixing of solute with solvent or multiple liquids takes place within the mixing channel 421 without the need for manual intervention in the mixing process. This further helps the liquid sample processing device 100 meet the development needs of automation and intelligence, reduces the risk of liquid contamination due to contact with air, and also reduces the risk of changes in sample concentration due to liquid evaporation when processing low-boiling-point liquid samples.

[0070] The mixing channel 421 and the liquid channel 411 are designed as an integral structure, which is beneficial to complete the sampling of liquid and the mixing of multiple liquids within the injection needle 400. This helps to shorten the processing time of a single sample, improve experimental efficiency, reduce the number of parts in the liquid sample processing device 100, and make the structure of the liquid sample processing device 100 more compact.

[0071] In some examples of embodiments of the present invention, as shown in FIG9, the drive mechanism 500 has a mounting bracket 540, the injection pin 400 is mounted on the mounting bracket 540, and the injection pin 400 is movable relative to the mounting bracket 540 along the axial direction of the injection pin 400.

[0072] The mounting bracket 540 can be fixedly connected to the third moving part 535. The injection pin 400 is movable relative to the mounting bracket 540 along the axial direction of the injection pin 400, which allows the injection pin 400 to adaptively adjust the insertion depth of the insertion end 440 of the injection pin 400 according to the height of the sample bottle 300, the bottle mouth depth, or the axial length of the injection port 610, thereby further improving the versatility of the liquid sample processing device 100.

[0073] When the drive mechanism 500 drives the sample injection needle 400 to move through the first drive unit 510, the second drive unit 520, and the third drive unit 530, there may be a slight positioning error. The sample injection needle 400 is movable relative to the mounting bracket 540 along the axial direction of the sample injection needle 400. This allows the sample injection needle 400 to adaptively adjust its position in the vertical direction through axial movement, reducing the risk of hard contact between the sample injection needle 400 and other structural components, reducing the risk of damage to the sample injection needle 400, and helping to ensure the reliability of the sampling process of the liquid sample processing device 100.

[0074] In some examples of embodiments of the present invention, as shown in FIG9, the drive mechanism 500 further includes an elastic reset member 550, the mounting bracket 540 forms a mounting cavity 560, the sample injection needle 400 passes through the mounting cavity 560, the outer peripheral wall of the sample injection needle 400 forms a limiting boss 430 located in the mounting cavity 560, the mounting cavity 560 forms a limiting surface 561 that is opposite to and spaced apart from the limiting boss 430 along the axial direction of the sample injection needle 400, the limiting surface 561 is located on the side of the limiting boss 430 away from the insertion end 440 of the sample injection needle 400, the elastic reset member 550 is located in the mounting cavity 560 and between the limiting boss 430 and the limiting surface 561, and the elastic reset member 550 is in contact with both the limiting boss 430 and the limiting surface 561.

[0075] As shown in Figure 9, the elastic reset member 550 can be constructed as a spring. When the injection needle 400 is inserted into the sample vial 300 and contacts the bottom wall of the sample vial 300, the bottom wall of the sample vial 300 will exert an upward vertical reaction force on the injection needle 400. This reaction force can cause the injection needle 400 to move towards the limiting surface 561, compressing the elastic reset member 550. The elastic reset member 550 absorbs stress through elastic deformation, thereby reducing the risk of breakage of the injection needle 400 and damage to the mouth of the sample vial 300, and improving the safety of the liquid sample processing device 100. At the same time, after being compressed by the reaction force, the elastic reset member 550 will generate a spring force in the opposite direction to the reaction force, which can keep the insertion end 440 in contact with the bottom wall of the sample vial 300. This helps the injection needle 400 to completely extract the liquid in the sample vial 300, reducing the amount of liquid remaining in the sample vial 300.

[0076] After the injection needle 400 completes sampling, the drive mechanism 500 can drive the injection needle 400 to move upward, so that the injection needle 400 is no longer in contact with the bottom wall of the sample vial 300. At this time, the elastic reset member 550 is no longer squeezed, and releases elastic potential energy to generate an elastic force in the opposite direction to the reaction force. The elastic force can push the limiting boss 430 to move toward the insertion end 440, and then the limiting boss 430 drives the injection needle 400 to reset synchronously until the injection needle 400 returns to the initial position.

[0077] As an example, users can preset parameters such as the position of the target sample vial 300 in the first direction and the second direction, the sampling volume, and the injection sequence through the terminal device.

[0078] When using the liquid sample processing device 100 to extract a single solution (i.e., liquid), the user starts the liquid sample processing device 100.

[0079] Step 1: The drive mechanism 500 is activated. The first drive motor 511 of the first drive unit 510 drives the first threaded screw 516 to rotate. The rotation of the first threaded screw 516 drives the first moving part 515, the first contact body 570, the second drive unit 520, the third drive unit 530, and the sample injection needle 400 to move along the first direction until the sample injection needle 400 moves to the preset position of the sample vial 300 in the first direction. Then, the second drive motor 521 of the second drive unit 520 drives the second threaded screw 526 to rotate. The rotation of the second threaded screw 526 drives the second moving part 525, the third drive unit 530, and the sample injection needle 400 to move along the second direction until the sample injection needle 400 moves directly above the target sample vial 300. Subsequently, the third drive motor 531 of the third drive unit 530 can drive the third threaded screw 536 to rotate, causing the third moving part 535 and the injection pin 400 to move downwards in the vertical direction, so that the insertion end 440 of the injection pin 400 passes through the mouth of the sample bottle 300 and extends below the liquid surface inside the sample bottle 300. If there is a positioning error or a height deviation of the sample bottle 300, the injection pin 400 can adaptively move relative to the mounting bracket 540 along the axial direction of the injection pin 400, squeezing the elastic reset member 550 to avoid hard contact between the injection pin 400 and the sample bottle 300.

[0080] As an example, before the insertion end 440 of the injection pin 400 extends below the liquid surface in the sample vial 300, the terminal device can control the drive pump structure 800 to drive the injection pin 400 to draw in a pre-set length of air column. This helps to reduce the risk of sample contamination caused by contact between the liquid and residual cleaning fluid or previous sample in the injection pin 400 during subsequent sampling.

[0081] Step 2: The first drive pump 810 is started, drawing the solution in the sample vial 300 into the injection needle 400. The solution flows sequentially through the liquid flow channel 411 of the needle section 410 and into the mixing flow channel 421 of the mixing section 420 until the solvent in the mixing flow channel 421 reaches the preset volume, at which point the first drive pump 810 stops.

[0082] Step 3: Next, the third drive unit 530 drives the injection pin 400 upward until the injection pin 400 disengages from the sample vial 300. The elastic reset member 550 releases its elastic potential energy, causing the injection pin 400 to return to the preset position. The first drive unit 510 and the second drive unit 520 work together to drive the injection pin 400 to move along the first direction and the second direction to directly above the injection port 610. The third drive unit 530 then drives the injection pin 400 downward to insert into the injection port 610.

[0083] Step 4: The terminal device automatically switches the control unit 600 to the first connected state. The liquid storage structure 700 is connected to the sample inlet 610 through the second interface 640. The first drive pump 810 is started, and the solution flows into the liquid storage structure 700 through the sample inlet 610 and the second interface 640. When it is necessary to output the solution to the target container or reaction system, the control unit 600 can automatically switch to the second connected state. The second drive pump 820 is started, and the solution flows through the third interface 650 and flows out of the liquid storage structure 700 from the sample outlet 620.

[0084] Step 5: After all the solution in the storage structure 700 has flowed out, the second drive pump 820 stops working. The third drive unit 530 drives the injection needle 400 upward until the injection needle 400 disengages from the injection port 610. Then, the operation of Step 1 is repeated, and the drive pump structure 800 drives the injection needle 400 to draw in the cleaning solution. With the cooperation of the first drive pump 810 and the second drive pump 820, the cleaning solution flows through the inside of the injection needle 400, the inside of the control unit 600, and the inside of the storage structure 700, and is discharged from the waste liquid outlet 660.

[0085] When using the liquid sample processing device 100 to extract and mix multiple solutions, the user starts the liquid sample processing device 100.

[0086] Step 1: This is exactly the same as Step 1 in the above embodiment when preparing a single solution using the liquid sample processing device 100.

[0087] Step Two: The first drive pump 810 starts, drawing the first solution into the mixing channel 421 of the injection needle 400 until the first solution reaches the preset sampling volume, at which point the first drive pump 810 stops. Next, the third drive unit 530 drives the injection needle 400 upwards until the insertion end 440 of the injection needle 400 disengages from the sample vial 300 containing the first solution. The elastic reset member 550 releases its elastic potential energy, and the injection needle 400 returns to the preset position. Subsequently, the first drive unit 510 and the second drive unit 520 work together to move the injection needle 400 along the first and second directions to directly above the wash bottle. The third drive unit 530 then drives the injection needle 400 downwards, causing the insertion end 440 to be inserted below the surface of the cleaning solution in the wash bottle containing the cleaning solution. The cleaning solution cleans the insertion end 440, reducing the risk of cross-contamination between different solutions.

[0088] After the insertion end 440 is cleaned, the third drive unit 530 drives the injection needle 400 to move upward and disengage from the wash bottle. The elastic reset member 550 releases its elastic potential energy, and the injection needle 400 returns to the preset position. Then, the liquid sample processing device 100 repeats the process of step one, with the insertion end 440 of the injection needle 400 inserted below the liquid surface in the sample bottle 300 containing the second solution. The first drive pump 810 starts, drawing the second solution into the mixing section 420 of the injection needle 400 until the second solution reaches the preset sampling volume. Because the cross-sectional area of ​​the mixing channel 421 is larger than that of the liquid channel 411, the flow velocity of the second solution changes abruptly when it flows into the mixing section 420, creating turbulence and ensuring thorough mixing of the first and second solutions.

[0089] If more solutions need to be mixed, repeat the process from cleaning the insertion end 440 in the above embodiment until all preset solutions have been extracted and mixed evenly. The mixed solution is temporarily stored in the mixing section 420 of the injection needle 400.

[0090] Step 3: After the last solution is extracted and mixed, the first drive pump 810 stops working. The third drive unit 530 drives the injection needle 400 to move upward and disengage from the last sample vial 300. The elastic reset member 550 releases its elastic potential energy, and the injection needle 400 returns to the preset position. The first drive unit 510 and the second drive unit 520 work together to drive the injection needle 400 to move along the first direction and the second direction until the insertion end 440 moves directly above the injection port 610. The third drive unit 530 then drives the injection needle 400 downward, so that the insertion end 440 is inserted into the injection port 610.

[0091] Step 4: The terminal device switches the control unit 600 to the first connected state. The liquid storage structure 700 is connected to the sample inlet 610 through the second interface 640. The first drive pump 810 drives the mixture in the mixing section 420 to flow into the liquid storage structure 700. When it is necessary to output the mixture, the control unit 600 automatically switches to the second connected state, and the mixture can flow out of the liquid storage structure 700 from the sample outlet 620.

[0092] Step 5: After all the mixed liquid in the storage structure 700 has flowed out, the second drive pump 820 stops working, and the third drive unit 530 drives the injection needle 400 to move upward until the injection needle 400 disengages from the injection port 610. Then, the first drive unit 510, the second drive unit 520, and the third drive unit 530 work together to drive the injection needle 400 to the cleaning bottle containing the cleaning solution. The operation of Step 1 is repeated so that the injection needle 400 is inserted below the surface of the cleaning solution. The drive mechanism 500 drives the injection needle 400 to draw in the cleaning solution. The first drive pump 810 and the second drive pump 820 cooperate to make the cleaning solution flow through the inside of the injection needle 400, the inside of the control unit 600, and the inside of the storage structure 700, and finally discharge it from the waste liquid outlet 660 from the storage structure 700, completing the cleaning of the liquid flow path inside the entire liquid sample processing device 100.

[0093] Other configurations and operations of the liquid sample processing apparatus 100 according to embodiments of the present invention are known to those skilled in the art and will not be described in detail here.

[0094] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0095] Although embodiments of the invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A liquid sample processing device, characterized in that, include: A support structure (200) for supporting a sample vial (300) containing liquid; an injection needle (400) and a drive mechanism (500), the injection needle (400) being mounted on the drive mechanism (500) for driving the injection needle (400) to move; a control unit (600) and a liquid storage structure (700), the control unit (600) and the liquid storage structure (700) being connected, the control unit (600) having an inlet (610), an outlet (620) and a first interface (630), and the control unit (600) having a first connected state and a second connected state; a drive pump structure (800), the drive pump structure (800) being connected to the injection needle (400), the drive pump structure (800) being configured to... When the driving mechanism (500) drives the injection needle (400) to be inserted into the sample vial (300), it can drive the liquid in the sample vial (300) to be drawn into the injection needle (400). The driving pump structure (800) is also configured to drive the liquid in the injection needle (400) to flow into the liquid storage structure (700) when the driving mechanism (500) drives the injection needle (400) to be inserted into the injection port (610) and the control unit (600) is in the first communication state. The driving pump structure (800) is also connected to the first interface (630). The driving pump structure (800) is also configured to drive the liquid in the liquid storage structure (700) to flow out from the sample outlet (620) when the control unit (600) is in the second communication state.

2. The liquid sample processing device according to claim 1, characterized in that, When the control unit (600) is in the first connected state, the liquid storage structure (700) is connected to the sample inlet (610); when the control unit (600) is in the second connected state, the liquid storage structure (700) is connected to the sample outlet (620) and the first interface (630).

3. The liquid sample processing apparatus according to claim 2, characterized in that, The control unit (600) also has a second interface (640) and a third interface (650). The liquid storage structure (700) is connected to the second interface (640) and the third interface (650). When the control unit (600) is in the first connected state, the second interface (640) is connected to the sample inlet (610) and the liquid storage structure (700). When the control unit (600) is in the second connected state, the second interface (640) is connected to the first interface (630) and the liquid storage structure (700), and the third interface (650) is connected to the liquid storage structure (700) and the sample outlet (620).

4. The liquid sample processing apparatus according to claim 2, characterized in that, The control unit (600) also has a waste liquid outlet (660), and when the control unit (600) is in the first connected state, the liquid storage structure (700) connects the sample inlet (610) and the waste liquid outlet (660).

5. The liquid sample processing apparatus according to claim 1, characterized in that, The drive pump structure (800) includes: a first drive pump (810) connected to the injection needle (400), the first drive pump (810) being configured to drive the liquid in the sample vial (300) into the injection needle (400), and also configured to drive the liquid in the injection needle (400) into the liquid storage structure (700); and a second drive pump (820) connected to the first interface (630), the second drive pump (820) being configured to drive the liquid in the liquid storage structure (700) to flow out from the sample outlet (620).

6. The liquid sample processing apparatus according to claim 1, characterized in that, The supporting structure (200) and the control unit (600) are arranged along a first direction, and the injection port (610) is located on the upper side of the control unit (600). The driving mechanism (500) is used to drive the injection needle (400) to move along the first direction, the second direction and the vertical direction, wherein the first direction, the second direction and the vertical direction are perpendicular to each other.

7. The liquid sample processing apparatus according to claim 6, characterized in that, The driving mechanism (500) includes: a first driving part (510), a second driving part (520), and a third driving part (530). The second driving part (520) is mounted on the first driving part (510), the third driving part (530) is mounted on the second driving part (520), and the injection pin (400) is mounted on the third driving part (530). The first driving part (510) is used to drive the second driving part (520), the third driving part (530), and the injection pin (400) to move synchronously along the first direction. The second driving part (520) is used to drive the third driving part (530) and the injection pin (400) to move synchronously along the second direction. The third driving part (530) is used to drive the injection pin (400) to move along the vertical direction.

8. The liquid sample processing apparatus according to any one of claims 1-7, characterized in that, The injection needle (400) includes a needle section (410) and a mixing section (420) connected together. A mixing channel (421) is formed in the mixing section (420), and a liquid channel (411) communicating with the mixing channel (421) is formed in the needle section (410). The cross-sectional area of ​​the mixing channel (421) is larger than the cross-sectional area of ​​the liquid channel (411).

9. The liquid sample processing apparatus according to any one of claims 1-7, characterized in that, The drive mechanism (500) has a mounting bracket (540), the injection pin (400) is mounted on the mounting bracket (540), and the injection pin (400) is movable relative to the mounting bracket (540) along the axial direction of the injection pin (400).

10. The liquid sample processing apparatus according to claim 9, characterized in that, The drive mechanism (500) also has an elastic reset member (550), the mounting bracket (540) forms a mounting cavity (560), the injection pin (400) passes through the mounting cavity (560), the outer peripheral wall of the injection pin (400) forms a limiting boss (430) located in the mounting cavity (560), and the mounting cavity (560) forms a axial direction of the injection pin (400) along with the limiting boss (430). The limiting surfaces (561) are opposite and spaced apart. The limiting surfaces (561) are located on the side of the limiting boss (430) away from the insertion end (440) of the injection pin (400). The elastic reset member (550) is located in the mounting cavity (560) and between the limiting boss (430) and the limiting surface (561). The elastic reset member (550) is in contact with both the limiting boss (430) and the limiting surface (561).

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